AU2002213485A1 - Inhibitors of protein kinases - Google Patents
Inhibitors of protein kinasesInfo
- Publication number
- AU2002213485A1 AU2002213485A1 AU2002213485A AU1348502A AU2002213485A1 AU 2002213485 A1 AU2002213485 A1 AU 2002213485A1 AU 2002213485 A AU2002213485 A AU 2002213485A AU 1348502 A AU1348502 A AU 1348502A AU 2002213485 A1 AU2002213485 A1 AU 2002213485A1
- Authority
- AU
- Australia
- Prior art keywords
- inhibitors
- protein kinases
- kinases
- protein
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 102000001253 Protein Kinase Human genes 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
- 108060006633 protein kinase Proteins 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P13/12—Drugs for disorders of the urinary system of the kidneys
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/689,943 US6297238B1 (en) | 1999-04-06 | 2000-10-12 | Therapeutic agents |
US09689943 | 2000-10-12 | ||
PCT/US2001/042715 WO2002030908A1 (en) | 2000-10-12 | 2001-10-12 | Inhibitors of protein kinases |
Publications (1)
Publication Number | Publication Date |
---|---|
AU2002213485A1 true AU2002213485A1 (en) | 2002-04-22 |
Family
ID=24770473
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU2002213485A Abandoned AU2002213485A1 (en) | 2000-10-12 | 2001-10-12 | Inhibitors of protein kinases |
Country Status (9)
Country | Link |
---|---|
US (1) | US6297238B1 (en) |
EP (1) | EP1268437A1 (en) |
JP (1) | JP2004511470A (en) |
AU (1) | AU2002213485A1 (en) |
CA (1) | CA2394084A1 (en) |
HK (1) | HK1053832A1 (en) |
MX (1) | MXPA02005844A (en) |
UY (1) | UY26968A1 (en) |
WO (1) | WO2002030908A1 (en) |
Families Citing this family (47)
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WO1999037751A1 (en) * | 1998-01-23 | 1999-07-29 | Imclone Systems Incorporated | Purified populations of stem cells |
US7223724B1 (en) | 1999-02-08 | 2007-05-29 | Human Genome Sciences, Inc. | Use of vascular endothelial growth factor to treat photoreceptor cells |
GB0005345D0 (en) * | 2000-03-06 | 2000-04-26 | Mathilda & Terence Kennedy Ins | Methods of treating sepsis septic shock and inflammation |
MXPA02003434A (en) * | 2000-08-04 | 2002-09-02 | Human Genome Sciences Inc | Vascular endothelial growth factor 2. |
US20050232921A1 (en) * | 2001-04-13 | 2005-10-20 | Rosen Craig A | Vascular endothelial growth factor 2 |
ATE330956T1 (en) * | 2001-04-13 | 2006-07-15 | Pfizer Prod Inc | BIZYCLIC SUBSTITUTED 4-AMINOPYRIDOPYRIMIDINE DERIVATIVES |
US20030176674A1 (en) * | 2001-04-13 | 2003-09-18 | Rosen Craig A. | Vascular endothelial growth factor 2 |
WO2002083704A1 (en) * | 2001-04-13 | 2002-10-24 | Human Genome Sciences, Inc. | Vascular endothelial growth factor 2 |
JP2005508298A (en) * | 2001-06-20 | 2005-03-31 | イムクローン システムズ インコーポレイティド | Methods for treating atherosclerosis and other inflammatory diseases |
EP1423012B1 (en) * | 2001-08-10 | 2007-11-14 | Imclone Systems, Inc. | Medical use of stem cells expressing vegfr-1 |
US7202066B2 (en) * | 2002-01-29 | 2007-04-10 | Carrington Laboratories, Inc. | Combination of a growth factor and a protease enzyme |
DK1916001T3 (en) * | 2002-03-04 | 2011-07-18 | Imclone Llc | KDR-specific human antibodies and uses thereof |
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US7232842B2 (en) | 2003-01-10 | 2007-06-19 | Board Of Trustees Of The Leland Stanford Junior University | Kinase inhibitors and associated pharmaceutical compositions and methods of use |
US20040254159A1 (en) * | 2003-02-27 | 2004-12-16 | Hasvold Lisa A. | Heterocyclic kinase inhibitors |
US7456169B2 (en) | 2003-02-27 | 2008-11-25 | Abbott Laboratories Inc. | Heterocyclic kinase inhibitors |
US7320986B2 (en) * | 2003-03-07 | 2008-01-22 | Abbott Labortories | Fused tri and tetra-cyclic pyrazole kinase inhibitors |
CA2517885A1 (en) * | 2003-03-07 | 2004-09-23 | Abbott Laboratories | Fused tri and tetra-cyclic pyrazole kinase inhibitors |
DE602004027288D1 (en) * | 2003-09-08 | 2010-07-01 | Aventis Pharma Inc | Thienopyrazole |
JP4716873B2 (en) * | 2003-10-14 | 2011-07-06 | 聰 竹尾 | Agent for improving intellectual disability |
US7468371B2 (en) * | 2004-03-24 | 2008-12-23 | Abbott Laboratories Inc. | Tricyclic pyrazole kinase inhibitors |
EP1819358B1 (en) | 2004-11-18 | 2014-09-17 | ImClone LLC | Antibodies against vascular endothelial growth factor receptor-1 |
US20070060589A1 (en) * | 2004-12-21 | 2007-03-15 | Purandare Ashok V | Inhibitors of protein arginine methyl transferases |
CA2645137A1 (en) | 2006-03-07 | 2007-09-13 | James F. Blake | Heterobicyclic pyrazole compounds and methods of use |
EP2032538A2 (en) * | 2006-06-08 | 2009-03-11 | Array Biopharma, Inc. | Quinoline compounds and methods of use |
WO2008079972A2 (en) | 2006-12-20 | 2008-07-03 | Bayer Healthcare Llc | 4-{4- [ ({3-tert-butyl-1- [3- (hydroxymethyl) phenyl] - 1h- pyrazol- 5 -yl } carbamoyl) -amin o] -3-chlorophenoxy} -n-methylpyridine-2-carboxamide as an inhibitor of the vegfr kinase for the treatment of cancer |
US20110020326A1 (en) * | 2008-03-04 | 2011-01-27 | Children's Medical Center Corporation | Method of treating polycystic kidney disease |
CA2734172A1 (en) * | 2008-08-29 | 2010-03-04 | Genentech, Inc. | Diagnostics and treatments for vegf-independent tumors |
EP2483407A2 (en) | 2009-09-30 | 2012-08-08 | President and Fellows of Harvard College | Methods for modulation of autophagy through the modulation of autophagy-enhancing gene products |
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TW201728592A (en) | 2012-01-10 | 2017-08-16 | 林伯士艾瑞斯公司 | IRAK inhibitors and uses thereof |
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US8853207B2 (en) | 2012-04-12 | 2014-10-07 | Development Center For Biotechnology | Heterocyclic pyrazole compounds, method for preparing the same and use thereof |
WO2014011902A1 (en) | 2012-07-11 | 2014-01-16 | Nimbus Iris, Inc. | Irak inhibitors and uses thereof |
US20140018361A1 (en) * | 2012-07-11 | 2014-01-16 | Nimbus Iris, Inc. | Irak inhibitors and uses thereof |
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CN105142639A (en) | 2013-01-10 | 2015-12-09 | 林伯士艾瑞斯公司 | IRAK inhibitors and uses thereof |
US8778365B1 (en) | 2013-01-31 | 2014-07-15 | Merz Pharmaceuticals, Llc | Topical compositions and methods for making and using same |
BR112015021423A2 (en) | 2013-03-06 | 2017-07-18 | Genentech Inc | cancer treatment methods, egfr antagonist-resistant cancer cells, cancer cells, methods of increasing the sensitivity and effectiveness of cancer treatment, and methods of delaying, treating cancer patients and extending |
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US6462036B1 (en) * | 1998-11-06 | 2002-10-08 | Basf Aktiengesellschaft | Tricyclic pyrazole derivatives |
NZ514269A (en) * | 1999-04-06 | 2003-10-31 | Abbott Gmbh & Co | Substituted 1,4-dihydroindeno[1,2-c]pyrazoles useful as inhibitors of tyrosine kinase |
-
2000
- 2000-10-12 US US09/689,943 patent/US6297238B1/en not_active Expired - Lifetime
-
2001
- 2001-10-12 CA CA002394084A patent/CA2394084A1/en not_active Abandoned
- 2001-10-12 MX MXPA02005844A patent/MXPA02005844A/en unknown
- 2001-10-12 WO PCT/US2001/042715 patent/WO2002030908A1/en not_active Application Discontinuation
- 2001-10-12 JP JP2002534294A patent/JP2004511470A/en not_active Withdrawn
- 2001-10-12 UY UY26968A patent/UY26968A1/en not_active Application Discontinuation
- 2001-10-12 AU AU2002213485A patent/AU2002213485A1/en not_active Abandoned
- 2001-10-12 EP EP01981870A patent/EP1268437A1/en not_active Withdrawn
-
2003
- 2003-06-20 HK HK03104465.5A patent/HK1053832A1/en unknown
Also Published As
Publication number | Publication date |
---|---|
UY26968A1 (en) | 2002-06-20 |
US6297238B1 (en) | 2001-10-02 |
HK1053832A1 (en) | 2003-11-07 |
JP2004511470A (en) | 2004-04-15 |
CA2394084A1 (en) | 2002-04-18 |
MXPA02005844A (en) | 2004-08-12 |
WO2002030908A1 (en) | 2002-04-18 |
EP1268437A1 (en) | 2003-01-02 |
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