JP2010504957A5 - - Google Patents

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Publication number
JP2010504957A5
JP2010504957A5 JP2009529841A JP2009529841A JP2010504957A5 JP 2010504957 A5 JP2010504957 A5 JP 2010504957A5 JP 2009529841 A JP2009529841 A JP 2009529841A JP 2009529841 A JP2009529841 A JP 2009529841A JP 2010504957 A5 JP2010504957 A5 JP 2010504957A5
Authority
JP
Japan
Prior art keywords
aza
bicyclo
hex
thiazole
ylmethyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
JP2009529841A
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English (en)
Japanese (ja)
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JP2010504957A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/IB2007/053947 external-priority patent/WO2008038251A2/en
Publication of JP2010504957A publication Critical patent/JP2010504957A/ja
Publication of JP2010504957A5 publication Critical patent/JP2010504957A5/ja
Ceased legal-status Critical Current

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JP2009529841A 2006-09-29 2007-09-28 ３−アザ−ビシクロ［３．１．０］ヘキサン誘導体 Ceased JP2010504957A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IB2006053570 2006-09-29
PCT/IB2007/053947 WO2008038251A2 (en) 2006-09-29 2007-09-28 3-aza-bicyclo[3.1.0]hexane derivatives

Publications (2)

Publication Number Publication Date
JP2010504957A JP2010504957A (ja) 2010-02-18
JP2010504957A5 true JP2010504957A5 (enExample) 2013-03-28

Family

ID=39106344

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2009529841A Ceased JP2010504957A (ja) 2006-09-29 2007-09-28 ３−アザ−ビシクロ［３．１．０］ヘキサン誘導体

Country Status (13)

Country Link
US (1) US20100016401A1 (enExample)
EP (1) EP2079690B1 (enExample)
JP (1) JP2010504957A (enExample)
KR (1) KR20090077051A (enExample)
CN (1) CN101522618A (enExample)
AR (1) AR063081A1 (enExample)
AT (1) ATE481383T1 (enExample)
CA (1) CA2662612A1 (enExample)
CL (1) CL2007002809A1 (enExample)
DE (1) DE602007009284D1 (enExample)
ES (1) ES2350460T3 (enExample)
TW (1) TW200823227A (enExample)
WO (1) WO2008038251A2 (enExample)

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UA119151C2 (uk) 2013-12-03 2019-05-10 Ідорсія Фармасьютікалз Лтд КРИСТАЛІЧНА СОЛЬОВА ФОРМА (S)-(2-(6-ХЛОР-7-МЕТИЛ-1H-БЕНЗО[d]ІМІДАЗОЛ-2-ІЛ)-2-МЕТИЛПІРОЛІДИН-1-ІЛ)(5-МЕТОКСИ-2-(2H-1,2,3-ТРИАЗОЛ-2-ІЛ)ФЕНІЛ)МЕТАНОНУ ЯК АНТАГОНІСТ ОРЕКСИНОВОГО РЕЦЕПТОРА
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KR102738491B1 (ko) 2016-02-12 2024-12-03 아스트라제네카 아베 오렉신 수용체 조정제로서의 할로-치환된 피페리딘
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US20190151304A1 (en) 2016-05-10 2019-05-23 Inserm (Institut National De La Santé Et De La Rechercjae Médicale Methods and pharmaceutical compositions for the treatment of autoimmune inflammatory
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WO2020007964A1 (en) 2018-07-05 2020-01-09 Idorsia Pharmaceuticals Ltd 2-(2-azabicyclo[3.1.0]hexan-1-yl)-1h-benzimidazole derivatives
WO2020007977A1 (en) 2018-07-06 2020-01-09 Idorsia Pharmaceuticals Ltd 7-trifluoromethyl-[1,4]diazepan derivatives
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TW202400149A (zh) 2022-05-13 2024-01-01 瑞士商愛杜西亞製藥有限公司 經噻唑并芳基-甲基取代之環狀肼-n-甲醯胺衍生物
CN117126101A (zh) * 2023-08-28 2023-11-28 瑞博(杭州)医药科技有限公司 一种脯氨酸结构的盐酸盐中间体的高效制备方法
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DE602008002934D1 (de) * 2007-05-14 2010-11-18 Actelion Pharmaceuticals Ltd 2-cyclopropylthiazolderivate
NZ580887A (en) * 2007-05-23 2012-03-30 Merck Sharp & Dohme Pyridyl piperidine orexin receptor antagonists
ES2371514T3 (es) * 2007-07-03 2012-01-04 Actelion Pharmaceuticals Ltd. Compuestos de 3-aza-biciclo[3.3.0]octano.
ATE493386T1 (de) * 2007-07-27 2011-01-15 Actelion Pharmaceuticals Ltd Trans-3-aza-bicyclo-ä3.1.0ü-hexan-derivate
AR067665A1 (es) * 2007-07-27 2009-10-21 Actelion Pharmaceuticals Ltd Derivados de trans-3- aza-biciclo ( 3.1.0) hexano
CN101874028B (zh) * 2007-07-27 2012-11-14 埃科特莱茵药品有限公司 2-氮杂-二环[3.3.0]辛烷衍生物
US8288411B2 (en) * 2007-09-24 2012-10-16 Actelion Pharmaceuticals Ltd. Pyrrolidines and piperidines as orexin receptor antagonists
CN101965343A (zh) * 2008-02-21 2011-02-02 埃科特莱茵药品有限公司 2-氮杂-双环[2.2.1]庚烷衍生物
WO2009133522A1 (en) * 2008-04-30 2009-11-05 Actelion Pharmaceuticals Ltd Piperidine and pyrrolidine compounds

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