JP2009542681A5 - - Google Patents

Download PDF

Info

Publication number
JP2009542681A5
JP2009542681A5 JP2009518331A JP2009518331A JP2009542681A5 JP 2009542681 A5 JP2009542681 A5 JP 2009542681A5 JP 2009518331 A JP2009518331 A JP 2009518331A JP 2009518331 A JP2009518331 A JP 2009518331A JP 2009542681 A5 JP2009542681 A5 JP 2009542681A5
Authority
JP
Japan
Prior art keywords
composition
pdgf
tendon
composition according
biocompatible matrix
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2009518331A
Other languages
English (en)
Japanese (ja)
Other versions
JP5484047B2 (ja
JP2009542681A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2007/015345 external-priority patent/WO2008005427A2/en
Publication of JP2009542681A publication Critical patent/JP2009542681A/ja
Publication of JP2009542681A5 publication Critical patent/JP2009542681A5/ja
Application granted granted Critical
Publication of JP5484047B2 publication Critical patent/JP5484047B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2009518331A 2006-06-30 2007-07-02 回旋筋腱板傷害を処置するためのpdgf−生体マトリックス組成物および方法 Expired - Fee Related JP5484047B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US81787406P 2006-06-30 2006-06-30
US60/817,874 2006-06-30
PCT/US2007/015345 WO2008005427A2 (en) 2006-06-30 2007-07-02 Pdgf-biomatrix compositions and methods for treating rotator cuff injuries

Publications (3)

Publication Number Publication Date
JP2009542681A JP2009542681A (ja) 2009-12-03
JP2009542681A5 true JP2009542681A5 (enExample) 2010-08-12
JP5484047B2 JP5484047B2 (ja) 2014-05-07

Family

ID=38821246

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2009518331A Expired - Fee Related JP5484047B2 (ja) 2006-06-30 2007-07-02 回旋筋腱板傷害を処置するためのpdgf−生体マトリックス組成物および方法

Country Status (7)

Country Link
US (5) US9642891B2 (enExample)
EP (2) EP2049145B1 (enExample)
JP (1) JP5484047B2 (enExample)
AU (1) AU2007269712B2 (enExample)
CA (1) CA2656278C (enExample)
ES (1) ES2664229T3 (enExample)
WO (1) WO2008005427A2 (enExample)

Families Citing this family (80)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7473678B2 (en) * 2004-10-14 2009-01-06 Biomimetic Therapeutics, Inc. Platelet-derived growth factor compositions and methods of use thereof
WO2007061889A2 (en) 2005-11-17 2007-05-31 Biomimetic Therapeutics, Inc. Maxillofacial bone augmentation using rhpdgf-bb and a biocompatible matrix
EP1991282B1 (en) * 2006-02-09 2013-06-19 BioMimetic Therapeutics, LLC Compositions and methods for treating bone
CA2656278C (en) 2006-06-30 2016-02-09 Biomimetic Therapeutics, Inc. Compositions and methods for treating rotator cuff injuries
US9161967B2 (en) 2006-06-30 2015-10-20 Biomimetic Therapeutics, Llc Compositions and methods for treating the vertebral column
US8444758B2 (en) 2006-10-19 2013-05-21 Eastman Chemical Company Low voc additives for extending the wet edge and open time of aqueous coatings
US8106008B2 (en) 2006-11-03 2012-01-31 Biomimetic Therapeutics, Inc. Compositions and methods for arthrodetic procedures
WO2008103690A2 (en) * 2007-02-20 2008-08-28 Biomimetic Therapeutics, Inc. Prevention and treatment for osteonecrosis and osteoradionecrosis of the jaw using pdgf and a bone matrix
EP2124831B1 (en) 2007-03-15 2016-07-06 Ortho-Space Ltd. Prosthetic devices
ES2422259T3 (es) * 2008-02-07 2013-09-10 Biomimetic Therapeutics Inc Composiciones para la osteogénesis por distracción
CN102098984B (zh) 2008-05-14 2017-06-23 史密夫和内修有限公司 关节镜下二头肌腱固定术修复装置
KR20110067035A (ko) * 2008-09-09 2011-06-20 바이오미메틱 세라퓨틱스, 인크. 건 및 인대 손상의 치료를 위한 혈소판-유래 성장 인자 조성물 및 방법
EP2385807A2 (en) 2008-12-09 2011-11-16 Smith & Nephew, Inc. Tissue repair assembly
US8858606B2 (en) 2008-12-09 2014-10-14 Smith & Nephew, Inc. Tissue repair assembly
WO2010081029A1 (en) 2009-01-08 2010-07-15 Rotation Medical, Inc. Implantable tendon protection systems and related kits and methods
US20100211174A1 (en) * 2009-02-19 2010-08-19 Tyco Healthcare Group Lp Method For Repairing A Rotator Cuff
AU2010221089A1 (en) * 2009-03-05 2011-09-15 Biomimetic Therapeutics, Inc. Platelet-derived growth factor compositions and methods for the treatment of osteochondral defects
US9179910B2 (en) 2009-03-20 2015-11-10 Rotation Medical, Inc. Medical device delivery system and method
US8231653B2 (en) * 2009-03-31 2012-07-31 Arthrex, Inc. Method of forming knotless double row construct with graft or patch fixed under repair site
US12471975B2 (en) 2009-06-04 2025-11-18 Rotation Medical, Inc. Methods and apparatus for deploying sheet-like materials
JP5718912B2 (ja) 2009-06-04 2015-05-13 ローテーション メディカル インコーポレイテッドRotation Medical,Inc. 移植物搬送システム及び搬送システムを準備する方法
JP5662427B2 (ja) 2009-06-04 2015-01-28 ローテーション メディカル インコーポレイテッドRotation Medical,Inc. 目的の組織にシート状材料を固定するための装置
US20120282235A1 (en) * 2009-09-25 2012-11-08 Ohashi Kevin L Implantable patch and surgical kit for preparation thereof
US8690960B2 (en) * 2009-11-24 2014-04-08 Covidien Lp Reinforced tissue patch
CN107080834A (zh) * 2010-02-22 2017-08-22 生物模拟治疗有限责任公司 用于治疗腱病的血小板衍生生长因子组合物和方法
US9198750B2 (en) 2010-03-11 2015-12-01 Rotation Medical, Inc. Tendon repair implant and method of arthroscopic implantation
WO2012105224A1 (ja) * 2011-01-31 2012-08-09 オリンパス株式会社 ワクチン・アジュバント
CA2825918C (en) 2011-02-15 2018-08-07 Rotation Medical, Inc. Methods and apparatus for delivering and positioning sheet-like materials
WO2012145059A1 (en) 2011-02-15 2012-10-26 Rotation Medical, Inc. Methods and apparatus for fixing sheet-like materials to a target tissue
US9289307B2 (en) 2011-10-18 2016-03-22 Ortho-Space Ltd. Prosthetic devices and methods for using same
WO2013062994A1 (en) 2011-10-25 2013-05-02 Biomimetic Therapeutics, Inc. Compositions and methods for treating full thickness burn injuries
US20130108683A1 (en) * 2011-10-25 2013-05-02 Biomimetic Therapeutics, Inc. Compositions and methods for treating partial and full thickness wounds and injuries
US9107661B2 (en) 2011-12-19 2015-08-18 Rotation Medical, Inc. Fasteners and fastener delivery devices for affixing sheet-like materials to bone or tissue
WO2013096224A1 (en) 2011-12-19 2013-06-27 Rotation Medical, Inc. Fasteners for affixing sheet -like materials to bone or tissue
AU2012355433B2 (en) 2011-12-19 2016-10-20 Rotation Medical, Inc. Apparatus and method for forming pilot holes in bone and delivering fasteners therein for retaining an implant
US9370356B2 (en) 2011-12-19 2016-06-21 Rotation Medical, Inc. Fasteners and fastener delivery devices for affixing sheet-like materials to bone or tissue
EP2797532B1 (en) 2011-12-29 2016-04-06 Rotation Medical, Inc. Apparatus for delivering and positioning sheet-like materials in surgery
WO2013101641A2 (en) 2011-12-29 2013-07-04 Rotation Medical, Inc. Anatomical location markers and methods of use in positioning sheet-like materials during surgery
WO2013101640A1 (en) 2011-12-29 2013-07-04 Rotation Medical, Inc. Guidewire having a distal fixation member for delivering and positioning sheet-like materials in surgery
US9345577B2 (en) * 2013-03-14 2016-05-24 Microaire Surgical Instruments Llc Balloon implant device
CA2945821C (en) 2014-05-09 2018-09-04 Rotation Medical, Inc. Medical implant delivery system for sheet-like implant
EP3166624B1 (en) 2014-07-09 2020-06-03 Mayo Foundation for Medical Education and Research Treating rotator cuff conditions
MX2017004520A (es) * 2014-10-14 2018-03-15 Lynch Samuel Composiciones para tratar heridas.
EP3215025B1 (en) 2014-11-04 2020-12-23 Rotation Medical, Inc. Medical implant delivery system
US10675019B2 (en) 2014-11-04 2020-06-09 Rotation Medical, Inc. Medical implant delivery system and related methods
EP4275620A3 (en) 2014-11-04 2024-01-17 Rotation Medical, Inc. Medical implant delivery system
WO2016175967A1 (en) * 2015-04-30 2016-11-03 Encore Medical, L.P. Soft tissue repair using a porous coating implant
US10898228B2 (en) 2015-05-06 2021-01-26 Rotation Medical, Inc. Medical implant delivery system and related methods
WO2016205186A1 (en) 2015-06-15 2016-12-22 Rotation Medical, Inc. Tendon repair implant and method of implantation
WO2017011762A1 (en) 2015-07-16 2017-01-19 Mayo Foundation For Medical Education And Research Treating rotator cuff conditions
WO2017046647A1 (en) 2015-09-18 2017-03-23 Ortho-Space Ltd. Intramedullary fixated subacromial spacers
US10172703B2 (en) 2015-10-01 2019-01-08 Arthrex, Inc. Joint kinematic reconstruction techniques
US10813742B2 (en) 2015-10-01 2020-10-27 Arthrex, Inc. Joint kinematic reconstruction techniques
AU2016344019B2 (en) 2015-10-30 2021-07-15 New York Society For The Relief Of The Ruptured And Crippled, Maintaining The Hospital For Special Surgery Suture sleeve patch and methods of delivery within an existing arthroscopic workflow
EP3370698B1 (en) 2015-11-03 2022-01-26 Zoetis Services LLC Sol-gel polymer composites and uses thereof
CA3008670A1 (en) 2015-12-31 2017-07-06 Rotation Medical, Inc. Fastener delivery system and related methods
US10314689B2 (en) 2015-12-31 2019-06-11 Rotation Medical, Inc. Medical implant delivery system and related methods
US11484401B2 (en) 2016-02-01 2022-11-01 Medos International Sarl Tissue augmentation scaffolds for use in soft tissue fixation repair
US20170273680A1 (en) 2016-02-01 2017-09-28 DePuy Synthes Products, Inc. Tissue augmentation tacks for use with soft tissue fixation repair systems and methods
US11357495B2 (en) 2016-02-01 2022-06-14 Medos International Sarl Tissue augmentation scaffolds for use with soft tissue fixation repair systems and methods
US9861410B2 (en) 2016-05-06 2018-01-09 Medos International Sarl Methods, devices, and systems for blood flow
US10568733B2 (en) 2017-01-24 2020-02-25 Arthrex, Inc. Anterior cable region superior capsule reconstructions
US11045981B2 (en) 2017-01-30 2021-06-29 Ortho-Space Ltd. Processing machine and methods for processing dip-molded articles
WO2018144858A1 (en) * 2017-02-02 2018-08-09 Nanofiber Solutions, Inc. Methods of improving bone-soft tissue healing using electrospun fibers
WO2019033082A1 (en) * 2017-08-11 2019-02-14 Theracell, Inc. DEMINERALIZED BONE FIBER COMPOSITION FOR INCREASED FASTENING
USD904615S1 (en) * 2017-10-31 2020-12-08 Sicage Llc Bone screw
EP3720385B1 (en) 2017-12-07 2023-09-27 Rotation Medical, Inc. Medical implant delivery system
US20200179573A1 (en) * 2018-12-06 2020-06-11 National Cheng Kung University Biodegradable metal alloy for anchoring detached tissue to hard tissue, method of making the same, and process for using the same
CN113677395A (zh) 2019-02-13 2021-11-19 帕萨尔美德他克有限公司 用于骨科治疗的植入式电磁场产生器
CN111068116B (zh) * 2019-12-28 2022-03-22 河北柯瑞生物医药有限公司 一种注射用软骨修复温敏凝胶及其制备方法
US11559330B2 (en) 2020-02-11 2023-01-24 Embody, Inc. Surgical cannula with removable pressure seal
EP4103106B1 (en) 2020-02-11 2026-03-11 Embody, Inc. Implant delivery device
AU2021220864B2 (en) 2020-02-11 2024-03-07 Embody, Inc. Surgical anchoring device, deployment device, and method of use
US11957566B2 (en) * 2020-02-14 2024-04-16 B/G Ortho Innovations, LLC Implants and methods for shoulder joint reconstruction
CN111346262B (zh) * 2020-03-17 2022-02-01 四川大学 一种用于促进腱骨愈合的可注射钙磷陶瓷及其制备方法与应用
US12310928B2 (en) 2020-11-16 2025-05-27 University Of Utah Research Foundation Enthesis healing
CN113633821A (zh) * 2021-08-18 2021-11-12 上海交通大学医学院附属第九人民医院 一种温敏型可注射型胶原/壳聚糖/掺锌生物玻璃纳米颗粒水凝胶材料及其制备方法
CA3238654A1 (en) * 2021-11-16 2023-05-25 Mayo Foundation For Medical Education And Research Methods and compositions for repair of tendon-bone interface
US20240261086A1 (en) * 2023-02-07 2024-08-08 Cannuflow, Inc. Biological Patch and Fixation Device for Tendon Repair
CN121398834A (zh) * 2023-06-23 2026-01-23 塞缪尔·E·林奇 用于皮肤修复、恢复活性和舒适的方法和组合物

Family Cites Families (264)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3943072A (en) 1971-12-15 1976-03-09 United Kingdom Atomic Energy Authority Separation of molecules
USRE33161E (en) 1982-04-29 1990-02-06 American Dental Association Health Foundation Combinations of sparingly soluble calcium phosphates in slurries and pastes as mineralizers and cements
NL8402158A (nl) 1983-07-09 1985-02-01 Sumitomo Cement Co Poreus keramisch materiaal en werkwijze voor de bereiding daarvan.
US4837285A (en) * 1984-03-27 1989-06-06 Medimatrix Collagen matrix beads for soft tissue repair
US4889919A (en) 1986-08-13 1989-12-26 Zymogenetics, Inc. Biologically active PDGF derived A-chain homodimers
US5187263A (en) 1984-10-12 1993-02-16 Zymogenetics, Inc. Expression of biologically active PDGE analogs in eucaryotic cells
US4766073A (en) 1985-02-25 1988-08-23 Zymogenetics Inc. Expression of biologically active PDGF analogs in eucaryotic cells
US5165938A (en) 1984-11-29 1992-11-24 Regents Of The University Of Minnesota Wound healing agents derived from platelets
US5629191A (en) 1985-01-03 1997-05-13 Integra Lifesciences Corporation Method of making a porous matrix particle
US5045633A (en) 1985-02-25 1991-09-03 Zymogenetics, Inc. Expression of biologically active PDGF analogs in eucaryotic cells
US5516896A (en) 1985-02-25 1996-05-14 Zymogenetics, Inc. Biologically active B-chain homodimers
US5106748A (en) 1986-07-01 1992-04-21 Genetics Institute, Inc. Dna sequences encoding 5 proteins
US5108922A (en) 1986-07-01 1992-04-28 Genetics Institute, Inc. DNA sequences encoding BMP-1 products
US5187076A (en) 1986-07-01 1993-02-16 Genetics Institute, Inc. DNA sequences encoding BMP-6 proteins
ZA874681B (en) 1986-07-01 1988-04-27 Genetics Inst Novel osteoinductive factors
US5013649A (en) 1986-07-01 1991-05-07 Genetics Institute, Inc. DNA sequences encoding osteoinductive products
CA1322714C (en) 1986-11-14 1993-10-05 Harry N. Antoniades Wound healing and bone regeneration
US5019559A (en) 1986-11-14 1991-05-28 President And Fellows Of Harvard College Wound healing using PDGF and IGF-II
US5124316A (en) 1986-11-14 1992-06-23 President And Fellows Of Harvard College Method for periodontal regeneration
DE3785758T2 (de) 1986-11-14 1993-08-05 Harvard College Wundheilung und knochenregeneration.
US5219759A (en) 1987-04-22 1993-06-15 Chiron Corporation Recombinant DNA encoding PDGF A-chain polypeptide and expression vectors
US5457093A (en) * 1987-09-18 1995-10-10 Ethicon, Inc. Gel formulations containing growth factors
US4874746A (en) 1987-12-22 1989-10-17 Institute Of Molecular Biology, Inc. Wound headling composition of TGF-alpha and PDGF
US5759815A (en) 1988-02-11 1998-06-02 Creative Biomolecules, Inc. Production of platelet derived growth factor (PDGF) an muteins thereof
US6586388B2 (en) 1988-04-08 2003-07-01 Stryker Corporation Method of using recombinant osteogenic protein to repair bone or cartilage defects
US4975526A (en) 1989-02-23 1990-12-04 Creative Biomolecules, Inc. Bone collagen matrix for zenogenic implants
US5962028A (en) 1988-04-20 1999-10-05 Norian Corporation Carbonated hydroxyapatite compositions and uses
US5129905A (en) 1988-04-20 1992-07-14 Norian Corporation Methods for in situ prepared calcium phosphate minerals
US5053212A (en) 1988-04-20 1991-10-01 Norian Corporation Intimate mixture of calcium and phosphate sources as precursor to hydroxyapatite
US4904259A (en) 1988-04-29 1990-02-27 Samuel Itay Compositions and methods for repair of cartilage and bone
US5110604A (en) * 1988-06-30 1992-05-05 Collagen Corporation Processes for producing collagen matrixes and methods of using same
US5219576A (en) 1988-06-30 1993-06-15 Collagen Corporation Collagen wound healing matrices and process for their production
US5034375A (en) 1988-08-10 1991-07-23 Institute Of Molecular Biology, Inc. Process of wound healing using PDGF and EGF
US5035887A (en) 1989-09-07 1991-07-30 Institute Of Moelcular Biology, Inc. Wound healing composition of IL-1 and PDGF or IGF-1
US5599558A (en) 1989-09-15 1997-02-04 Curative Technologies, Inc. Selecting amounts of platelet releasate for efficacious treatment of tissue
US5112354A (en) 1989-11-16 1992-05-12 Northwestern University Bone allograft material and method
US5011910A (en) 1989-12-28 1991-04-30 Washington University Reagent and method for determining activity of retroviral protease
US5071655A (en) 1990-01-12 1991-12-10 Baylink David J Pharmaceutical combination for treatment of bone-wasting diseases
JP3159216B2 (ja) * 1990-02-01 2001-04-23 ユニバーシティ オブ サウス フロリダ 白血球由来の成長因子
TW199858B (enExample) 1990-03-30 1993-02-11 Fujirebio Kk
ATE156363T1 (de) 1990-04-10 1997-08-15 Inst Molecular Biology Inc Wundheilung
DE69132823T2 (de) 1990-05-16 2002-07-18 Genetics Institute, Inc. Knochen- und knorpel-bildung hervorrufende proteine
EP0564502B1 (en) 1990-11-27 2002-01-30 The American National Red Cross Tissue sealant and growth factor containing compositions that promote accelerated wound healing
US5853746A (en) 1991-01-31 1998-12-29 Robert Francis Shaw Methods and compositions for the treatment and repair of defects or lesions in cartilage or bone using functional barrier
US5149691A (en) 1991-03-12 1992-09-22 Creative Biomolecules, Inc. Issue repair and regeneration through the use of platelet derived growth factor (pdgf) in combination with dexamethasone
JPH06500802A (ja) * 1991-06-14 1994-01-27 アムジエン・インコーポレーテツド コラーゲンフィルムによるタンパクのドラッグ・デリバリー
KR100255415B1 (ko) 1991-06-25 2000-05-01 브루스 엠. 에이센 비엠피-9 조성물
US5837258A (en) 1991-08-30 1998-11-17 University Of South Florida Induction of tissue, bone or cartilage formation using connective tissue growth factor
US5270300A (en) 1991-09-06 1993-12-14 Robert Francis Shaw Methods and compositions for the treatment and repair of defects or lesions in cartilage or bone
DE69233022T2 (de) 1991-11-04 2004-02-12 Genetics Institute, LLC, Cambridge Rekombinante knochenmorphogenetische protein heterodimere, zusammensetzungen und verfahren zur verwendung
AU3062392A (en) 1991-11-04 1993-06-07 Novo Nordisk A/S Pdgf gel formulation
HU218845B (hu) 1992-02-12 2000-12-28 Biopharm Gesellschaft Zur Biotechnologischen Entwicklung Von Pharmaka Mbh. Új növekedési/differenciáló faktorokat kódoló DNS-szekvenciák, e faktorokat tartalmazó gyógyszerkészítmények, DNS-molekulák, gazdaszervezetek, antitestek, diagnosztikai eljárások
WO1993020859A1 (en) 1992-04-20 1993-10-28 Board Of Regents Of The University Of Washington Sustained release compositions for delivery of growth factors
IL106278A0 (en) 1992-07-13 1993-11-15 Sumitomo Metal Ind Bone formation-inducing protein
DK0662146T3 (da) 1992-09-03 2000-11-13 Univ California Dorsalvævpåvirkende faktor og præparat
EP0690871A4 (en) 1993-01-12 1999-10-20 Univ Johns Hopkins Med GROWTH DIFFERENTIATION FACTOR-5
CA2153653C (en) 1993-01-12 2010-12-07 Se-Jin Lee Growth differentiation factor-9
EP1475440A3 (en) 1993-01-12 2004-11-17 The Johns Hopkins University School Of Medicine Growth differentiation factor-3
ES2201076T3 (es) 1993-03-19 2004-03-16 The Johns Hopkins University School Of Medicine Factor-8 de diferenciacion del crecimiento.
CN1104257C (zh) 1993-03-29 2003-04-02 津莫吉尼蒂克斯公司 含pdgf和维生素d的刺激成骨细胞生长的组合物
DK0698094T3 (da) 1993-05-12 2004-05-03 Inst Genetics Llc BMP-11-sammensætninger
DE69433742T2 (de) 1993-05-12 2005-07-07 Genetics Institute, LLC, Cambridge Bmp-10 zusammensetzungen
AU7205894A (en) 1993-06-08 1995-01-03 Neogenix, Inc. Purified natural and synthetic compounds for the treatment of osteoarthritis
EP0717633A4 (en) 1993-07-09 1998-05-20 Univ Johns Hopkins Med GROWTH DIFFERENTIATION FACTOR-7
CA2165776A1 (en) 1993-07-09 1995-01-19 The Johns Hopkins University School Of Medicine Growth differentiation factor-6
US5531794A (en) 1993-09-13 1996-07-02 Asahi Kogaku Kogyo Kabushiki Kaisha Ceramic device providing an environment for the promotion and formation of new bone
US6291206B1 (en) 1993-09-17 2001-09-18 Genetics Institute, Inc. BMP receptor proteins
CA2171546A1 (en) 1993-10-08 1995-04-20 The Johns Hopkins University School Of Medicine Growth differentiation factor-10
US5518680A (en) 1993-10-18 1996-05-21 Massachusetts Institute Of Technology Tissue regeneration matrices by solid free form fabrication techniques
DE69434651T2 (de) 1993-12-07 2007-03-08 Genetics Institute, Inc., Cambridge Bmp-12, bmp-13 und diese enthaltende sehne-induzierende zusammensetzungen
JP3362267B2 (ja) 1993-12-29 2003-01-07 日本特殊陶業株式会社 生体インプラント材料及びその製造方法
AU704178B2 (en) 1993-12-30 1999-04-15 Imperial Cancer Research Technology Ltd Vertebrate embryonic pattern-inducing hedgehog-like proteins
US5460962A (en) 1994-01-04 1995-10-24 Organogenesis Inc. Peracetic acid sterilization of collagen or collagenous tissue
JPH07250688A (ja) 1994-01-28 1995-10-03 Sagami Chem Res Center TGF−βスーパーファミリー蛋白質をコードするヒト新規cDNA
WO1995020967A1 (en) 1994-02-04 1995-08-10 Cell Therapeutics, Inc. Composition for wound healing, neuron growth and vascularization
US5942496A (en) 1994-02-18 1999-08-24 The Regent Of The University Of Michigan Methods and compositions for multiple gene transfer into bone cells
AU1999995A (en) 1994-04-08 1995-11-10 Atrix Laboratories, Inc. An adjunctive polymer system for use with medical device
AU2297395A (en) 1994-04-20 1995-11-16 Institute Of Molecular Biology, Inc. Administration of platelet-derived growth factor and bone seeking drugs for osteoporosis and bone regeneration
US7963997B2 (en) 2002-07-19 2011-06-21 Kensey Nash Corporation Device for regeneration of articular cartilage and other tissue
WO1996001845A1 (en) 1994-07-08 1996-01-25 The Johns Hopkins University School Of Medicine Growth differentiation factor-11
CA2195246A1 (en) 1994-07-13 1996-02-01 Se-Jin Lee Growth differentiation factor-12
US6180606B1 (en) 1994-09-28 2001-01-30 Gensci Orthobiologics, Inc. Compositions with enhanced osteogenic potential, methods for making the same and uses thereof
US5651766A (en) 1995-06-07 1997-07-29 Transfusion Technologies Corporation Blood collection and separation system
AU4137596A (en) 1994-10-31 1996-05-23 Sepracor, Inc. Method for the treatment of periodontal disease and a pharmaceutical composition useful in said method
US6281332B1 (en) 1994-12-02 2001-08-28 The Johns Hopkins University School Of Medicine Hedgehog-derived polypeptides
US5635372A (en) 1995-05-18 1997-06-03 Genetics Institute, Inc. BMP-15 compositions
US6541037B1 (en) 1995-05-19 2003-04-01 Etex Corporation Delivery vehicle
US6287341B1 (en) 1995-05-19 2001-09-11 Etex Corporation Orthopedic and dental ceramic implants
US6027742A (en) 1995-05-19 2000-02-22 Etex Corporation Bioresorbable ceramic composites
US5676976A (en) 1995-05-19 1997-10-14 Etex Corporation Synthesis of reactive amorphous calcium phosphates
ES2293137T3 (es) 1995-10-11 2008-03-16 Novartis Vaccines And Diagnostics, Inc. Combinacion de pdgf, kgf,igf e igfbp para curacion de heridas.
US5783217A (en) 1995-11-07 1998-07-21 Etex Corporation Low temperature calcium phosphate apatite and a method of its manufacture
US5747273A (en) 1996-05-07 1998-05-05 Diagnostic Systems Laboratories, Inc. Immunoassay of total insulin-like growth factor binding protein-1
AU2759397A (en) 1996-05-28 1998-01-05 1218122 Ontario Inc. Resorbable implant biomaterial made of condensed calcium phosphate particles
FR2749756B1 (fr) 1996-06-14 1998-09-11 Bioland Procede de preparation d'un materiau composite implantable, materiau obtenu, implant comprenant ce materiau et kit de mise en oeuvre
US5965403A (en) 1996-09-18 1999-10-12 Genetics Institute, Inc. Nucleic acids encoding bone morphogenic protein-16 (BMP-16)
CA2268156C (en) 1996-10-16 2007-05-29 Etex Corporation Bioceramic compositions
US6037519A (en) 1997-10-20 2000-03-14 Sdgi Holdings, Inc. Ceramic fusion implants and compositions
DE19646782C2 (de) 1996-11-13 2000-05-25 Merck Patent Gmbh Bioresorbierbare Polymerisationsprodukte aus strahlungshärtbaren Bindemittelsystemen
WO1998026080A1 (en) 1996-12-13 1998-06-18 Chiron Corporation Method for expression of heterologous proteins in yeast
US5866165A (en) 1997-01-15 1999-02-02 Orquest, Inc. Collagen-polysaccharide matrix for bone and cartilage repair
FR2758988B1 (fr) 1997-02-05 2000-01-21 S H Ind Procede d'elaboration de substituts osseux synthetiques d'architecture poreuse parfaitement maitrisee
EP1350525A3 (en) 1997-02-07 2003-12-10 Stryker Corporation Matrix-free osteogenic devices, implants and methods thereof
DE69823955T2 (de) 1997-03-04 2005-06-16 Technology Finance Corp. (Pty.) Ltd., Sandton Als knochenimplantat geeignetes erzeugnis
US20020098222A1 (en) 1997-03-13 2002-07-25 John F. Wironen Bone paste
US20010016646A1 (en) 1998-03-20 2001-08-23 David C. Rueger Osteogenic devices and methods of use thereof for repair of endochondral bone, osteochondral and chondral defects
US7041641B2 (en) 1997-03-20 2006-05-09 Stryker Corporation Osteogenic devices and methods of use thereof for repair of endochondral bone and osteochondral defects
JP3334558B2 (ja) * 1997-04-23 2002-10-15 富士レビオ株式会社 酵素免疫測定方法及び試験片
US20030032586A1 (en) 1997-05-15 2003-02-13 David C. Rueger Compositions for morphogen-induced osteogenesis
GB2325934A (en) 1997-06-03 1998-12-09 Polybiomed Ltd Treating metal surfaces to enhance bio-compatibility and/or physical characteristics
US6063624A (en) 1997-06-09 2000-05-16 Baxter International Inc. Platelet suspensions and methods for resuspending platelets
EP0896825B1 (en) 1997-08-14 2002-07-17 Sulzer Innotec Ag Composition and device for in vivo cartilage repair comprising nanocapsules with osteoinductive and/or chondroinductive factors
US6136029A (en) 1997-10-01 2000-10-24 Phillips-Origen Ceramic Technology, Llc Bone substitute materials
US6090998A (en) 1997-10-27 2000-07-18 University Of Florida Segmentally demineralized bone implant
WO1999030726A1 (en) 1997-12-15 1999-06-24 Page Roy C Improved method for attaching dental and orthopedic implants, ligaments, and tendons to bone
US20020018796A1 (en) 1998-01-28 2002-02-14 John F. Wironen Thermally sterilized bone paste
JP2000004875A (ja) 1998-06-23 2000-01-11 Teijin Ltd 増殖因子の産生誘導方法
SE514908C2 (sv) 1998-07-13 2001-05-14 Gs Dev Ab Medel för benrekonstruktion
PT1100488E (pt) 1998-07-28 2003-09-30 Synthes Ag Utilizacao de compostos de creatina para tratamento das celulas e tecidos do osso ou cartilagem
US20030114936A1 (en) 1998-10-12 2003-06-19 Therics, Inc. Complex three-dimensional composite scaffold resistant to delimination
US6224635B1 (en) 1998-11-06 2001-05-01 Hospital For Joint Diseases Implantation of surgical implants with calcium sulfate
US6663870B2 (en) * 1998-12-07 2003-12-16 Zymogenetics, Inc. Methods for promoting growth of bone using zvegf3
US6231528B1 (en) 1999-01-15 2001-05-15 Jonathan J. Kaufman Ultrasonic and growth factor bone-therapy: apparatus and method
EP1025871A1 (en) 1999-01-28 2000-08-09 F. Hoffmann-La Roche Ag Use of a melanoma inhibiting activity factor (MIA) for cartilage and bone repair
ES2209820T3 (es) 1999-02-04 2004-07-01 Sdgi Holdings, Inc. Composiciones esponjosas osteogenicas altamente mineralizadas, y usos de las mismas.
US6294187B1 (en) 1999-02-23 2001-09-25 Osteotech, Inc. Load-bearing osteoimplant, method for its manufacture and method of repairing bone using same
US7615373B2 (en) 1999-02-25 2009-11-10 Virginia Commonwealth University Intellectual Property Foundation Electroprocessed collagen and tissue engineering
KR20010043639A (ko) 1999-03-15 2001-05-25 키이스 디 혈소판 수거 시스템
US6296602B1 (en) 1999-03-17 2001-10-02 Transfusion Technologies Corporation Method for collecting platelets and other blood components from whole blood
ES2199815T3 (es) 1999-03-19 2004-03-01 The Regents Of The University Of Michigan Mineralizacion y desarrollo celular supeerficial sobre biomateriales.
JP4892133B2 (ja) 1999-04-12 2012-03-07 ハーベスト・テクノロジーズ・コーポレイション 血小板富有血漿及び/又は血小板濃縮物を製造する方法
SE515227C2 (sv) 1999-04-28 2001-07-02 Bruce Medical Ab Kropp för åstadkommande av in- och tillväxt av benvävnad och/ eller bindväv och sätt för framställning av kroppen
US6468543B1 (en) * 1999-05-03 2002-10-22 Zymogenetics, Inc. Methods for promoting growth of bone using ZVEGF4
US6710025B1 (en) * 1999-05-26 2004-03-23 The Brigham And Women's Hospital, Inc. Treatment of damaged tissue using agents that modulate the activity of alpha-smooth muscle actin
AU5444800A (en) 1999-05-27 2000-12-18 Research Foundation Of State University Of New York, The LTiGTin vitroLT/iGT cell culture device including cartilage and methods of usingthe same
DE19926083A1 (de) 1999-06-08 2000-12-14 Universitaetsklinikum Freiburg Biologisches Gelenkkonstrukt
US20040059416A1 (en) * 1999-06-22 2004-03-25 Murray Martha M. Biologic replacement for fibrin clot
US6964685B2 (en) * 1999-06-22 2005-11-15 The Brigham And Women's Hospital, Inc. Biologic replacement for fibrin clot
US6429013B1 (en) 1999-08-19 2002-08-06 Artecel Science, Inc. Use of adipose tissue-derived stromal cells for chondrocyte differentiation and cartilage repair
DE19940717A1 (de) 1999-08-26 2001-03-01 Gerontocare Gmbh Resorblerbares Knochenersatz- und Knochenaufbaumaterial
US6280191B1 (en) * 1999-09-03 2001-08-28 Christopher B. Gordon Distractor suitable for permanent implantation into bone
WO2001032197A2 (en) 1999-11-02 2001-05-10 Eli Lilly And Company Methods of using lp8, a pdgf-related protein, to treat musculoskeletal disorders
US6451059B1 (en) 1999-11-12 2002-09-17 Ethicon, Inc. Viscous suspension spinning process for producing resorbable ceramic fibers and scaffolds
AU1622801A (en) 1999-11-18 2001-05-30 Regents Of The University Of Michigan, The Sustained drug delivery from structural matrices
US7887551B2 (en) 1999-12-02 2011-02-15 Smith & Nephew, Inc. Soft tissue attachment and repair
WO2001041822A1 (en) 1999-12-09 2001-06-14 Biosyntech Canada Inc. Mineral-polymer hybrid composition
US6479418B2 (en) 1999-12-16 2002-11-12 Isotis N.V. Porous ceramic body
US20030103960A1 (en) 1999-12-22 2003-06-05 Pierre Philippart Sealant and bone generating product
CA2396016A1 (en) 1999-12-29 2001-07-05 Andy Bernhardt System for reconstituting pastes and methods of using same
AU4234901A (en) 2000-01-28 2001-08-07 Dot Dunnschicht Und Oberflache Inorganic resorbable bone substitute material and production method
WO2001057083A1 (en) 2000-02-04 2001-08-09 Zymogenetics, Inc. Methods for promoting growth of bone, ligament, and cartilage using zvegf4
JP2001217440A (ja) * 2000-02-04 2001-08-10 Kanegafuchi Chem Ind Co Ltd ハイブリッド型薄膜光電変換装置とそれに用いられる透光性積層体
AU2001241594A1 (en) 2000-02-18 2001-08-27 Regeneration Technologies, Inc. Implantable tissues infused with growth factors and other additives
IT1316769B1 (it) 2000-02-18 2003-05-12 Getters Spa Pannello evacuato per isolamento termico con ridotta conduzione dicalore ai bordi
US7022506B2 (en) 2000-02-23 2006-04-04 The Trustees Of The University Of Pennsylvania Method and device for treating osteoarthritis, cartilage disease, defects and injuries in the human knee
CA2401421A1 (en) 2000-03-03 2001-09-13 Smith & Nephew, Inc. Shaped particle and composition for bone deficiency and method of making the particle
US20030055511A1 (en) 2000-03-03 2003-03-20 Schryver Jeffrey E. Shaped particle comprised of bone material and method of making the particle
ES2272452T3 (es) * 2000-03-09 2007-05-01 Zimmer Orthobiologics, Inc. Producto de anclaje biologico de tejido conectivo al hueso.
AU784377B2 (en) 2000-03-14 2006-03-23 Arthur V. Sampaio Compositions and methods for affecting osteogenesis
US20020006437A1 (en) 2000-05-01 2002-01-17 Grooms Jamie M. Non-migration tissue capsule
US20020022885A1 (en) 2000-05-19 2002-02-21 Takahiro Ochi Biomaterial
AU2001262605A1 (en) 2000-05-19 2001-11-26 Europrint Holdings Limited Method and system for implementing a game
US7081240B1 (en) 2000-06-28 2006-07-25 Zimmer Orthobiologics, Inc. Protein mixtures for wound healing
CN1471412B8 (zh) 2000-06-29 2016-06-15 生物合成技术加拿大公司 用于修复和再生软骨和其它组织的组合物以及该组合物的用途
DK177997B1 (da) 2000-07-19 2015-02-23 Ed Geistlich Söhne Ag Für Chemische Ind Knoglemateriale og collagenkombination til opheling af beskadigede led
US6877735B2 (en) * 2000-07-19 2005-04-12 F&F Limited Paper sheet managing device and recording system
US6739112B1 (en) 2000-08-21 2004-05-25 Nu Vasive, Inc. Bone allograft packaging system
GB0020610D0 (en) 2000-08-21 2000-10-11 Dytech Corp Ltd Uses of porous carriers
US6585730B1 (en) 2000-08-30 2003-07-01 Opus Medical, Inc. Method and apparatus for attaching connective tissues to bone using a knotless suture anchoring device
US6773723B1 (en) * 2000-08-30 2004-08-10 Depuy Acromed, Inc. Collagen/polysaccharide bilayer matrix
JP2004512145A (ja) 2000-10-31 2004-04-22 デピュイ・アクロメッド・インコーポレイテッド 骨および軟骨の修復用の鉱物質化したコラーゲン−多糖類型基質
US20020127265A1 (en) * 2000-12-21 2002-09-12 Bowman Steven M. Use of reinforced foam implants with enhanced integrity for soft tissue repair and regeneration
CA2365376C (en) * 2000-12-21 2006-03-28 Ethicon, Inc. Use of reinforced foam implants with enhanced integrity for soft tissue repair and regeneration
US7192604B2 (en) 2000-12-22 2007-03-20 Ethicon, Inc. Implantable biodegradable devices for musculoskeletal repair or regeneration
JP2004533276A (ja) 2001-01-25 2004-11-04 リジェネレーション テクノロジーズ インク. 注射可能な多孔性骨グラフト材料
US7005135B2 (en) 2001-01-30 2006-02-28 Ethicon Inc. Glass scaffolds with controlled resorption rates and methods for making same
US20020169122A1 (en) 2001-02-23 2002-11-14 Wyeth Chondrogenic potential of human bone marrow-derived CD105+ cells by BMP
US6743232B2 (en) 2001-02-26 2004-06-01 David W. Overaker Tissue scaffold anchor for cartilage repair
US6575986B2 (en) 2001-02-26 2003-06-10 Ethicon, Inc. Scaffold fixation device for use in articular cartilage repair
US6949251B2 (en) 2001-03-02 2005-09-27 Stryker Corporation Porous β-tricalcium phosphate granules for regeneration of bone tissue
US20030049328A1 (en) 2001-03-02 2003-03-13 Dalal Paresh S. Porous beta-tricalcium phosphate granules and methods for producing same
WO2002102783A1 (en) 2001-06-19 2002-12-27 Merck & Co., Inc. Tyrosine kinase inhibitors
US20030109537A1 (en) 2001-07-09 2003-06-12 Turner Russell T. Methods and materials for treating bone conditions
AU2002316694B2 (en) * 2001-07-16 2007-09-06 Depuy Products, Inc. Hybrid biologic/synthetic porous extracellular matrix scaffolds
CA2460026C (en) 2001-09-24 2011-06-28 Millenium Biologix Inc. Porous ceramic composite bone grafts
DE60224822T2 (de) * 2001-10-19 2009-01-22 Zymogenetics, Inc., Seattle Dimerisierter wachstumsfaktor sowie materialien und verfahren zu seiner herstellung
US6649072B2 (en) 2001-11-16 2003-11-18 Robert Brandt Method for producing autologous platelet-rich plasma
AU2002365969A1 (en) 2001-11-20 2003-06-10 Scott Bruder Flowable osteogenic and chondrogenic compositions
US7045105B2 (en) 2001-12-21 2006-05-16 Lagow Richard J Calcium phosphate bone replacement materials and methods of use thereof
US20030180344A1 (en) 2002-02-05 2003-09-25 Cambridge Scientific, Inc. Bioresorbable osteoconductive compositions for bone regeneration
AU2003210996A1 (en) 2002-02-11 2003-09-04 Zymogenetics, Inc. Materials and methods for preparing dimeric growth factors
US7879107B2 (en) 2002-02-20 2011-02-01 The Cleveland Clinic Foundation Composition and method for inducing bone growth and healing
DK175356B1 (da) 2002-02-28 2004-09-06 Coloplast As Stomiindretning
JP3739715B2 (ja) 2002-03-19 2006-01-25 オリンパス株式会社 人工骨および組織工学用担体
KR100460685B1 (ko) 2002-04-10 2004-12-09 재단법인서울대학교산학협력재단 인산칼슘계 화합물을 이용한 인공 골 충진재 및 그 제조방법
AU2003228587A1 (en) * 2002-04-18 2003-11-03 University Of Florida Biomimetic organic/inorganic composites, processes for their production, and methods of use
CA2485090A1 (en) * 2002-05-02 2003-12-24 Osteoscreen, Inc. Methods and compositions for stimulating bone growth using nitric oxide releasing bisphosphonate conjugates (no-bisphosphonate)
US20040033949A1 (en) 2002-05-06 2004-02-19 Genentech, Inc. Use of VEGF for treating bone defects
US7368125B2 (en) 2002-06-05 2008-05-06 Ethicon, Inc. Amphiphilic polymers for medical applications
US7041309B2 (en) 2002-06-13 2006-05-09 Neuropro Technologies, Inc. Spinal fusion using an HMG-CoA reductase inhibitor
CA2432583A1 (en) 2002-06-20 2003-12-20 Merck Patent Gesellschaft Mit Beschraenkter Haftung Method of preparing alpha- and beta-tricalcium phosphate powders
US20040002770A1 (en) 2002-06-28 2004-01-01 King Richard S. Polymer-bioceramic composite for orthopaedic applications and method of manufacture thereof
ES2242916T3 (es) 2002-07-11 2005-11-16 Biomet Deutschland Gmbh Metodos de preparacion de segmentos y granulos de fosfato de calcio poroso mediante procesamiento con gelatina.
US7744651B2 (en) 2002-09-18 2010-06-29 Warsaw Orthopedic, Inc Compositions and methods for treating intervertebral discs with collagen-based materials
EP1563846B1 (en) 2002-10-10 2012-08-29 Ono Pharmaceutical Co., Ltd. Endogenous repair factor production promoters
US20040078090A1 (en) 2002-10-18 2004-04-22 Francois Binette Biocompatible scaffolds with tissue fragments
US7824701B2 (en) * 2002-10-18 2010-11-02 Ethicon, Inc. Biocompatible scaffold for ligament or tendon repair
AU2003203316B2 (en) 2003-02-13 2007-01-11 Synthes Gmbh Injectable bone-replacement mixture
US20040230309A1 (en) 2003-02-14 2004-11-18 Depuy Spine, Inc. In-situ formed intervertebral fusion device and method
WO2004078069A2 (en) 2003-03-05 2004-09-16 Therics, Inc. Process for manufacturing biomedical articles by infiltrating biocompatible metal alloys in porous matrices
US20040193270A1 (en) 2003-03-31 2004-09-30 Depuyacromed, Inc. Implantable bone graft
US7901457B2 (en) 2003-05-16 2011-03-08 Musculoskeletal Transplant Foundation Cartilage allograft plug
KR20060031808A (ko) 2003-06-11 2006-04-13 오스테오테크, 인코포레이티드 뼈 임플란트 및 그의 제조 방법
US6974862B2 (en) 2003-06-20 2005-12-13 Kensey Nash Corporation High density fibrous polymers suitable for implant
ATE396669T1 (de) 2003-06-24 2008-06-15 Robert Mathys Foundation Dr H Prothesenvorrichtung zur wiederherstellung von knorpel
DE10328892A1 (de) 2003-06-26 2005-05-12 Curasan Ag Knochenaufbaumittel und Herstellungsverfahren
ES2564044T3 (es) 2003-06-27 2016-03-17 DePuy Synthes Products, Inc. Células posparto derivadas de tejido del cordón umbilical y métodos de preparación y uso de las mismas
FI20031120A0 (fi) 2003-07-31 2003-07-31 Bci Bioabsorbable Concepts Ltd Monifunktionaalinen implanttilaite
US7163920B2 (en) 2003-09-30 2007-01-16 Ethicon, Inc. Peptide with osteogenic activity
CU23352A1 (es) 2003-10-16 2009-03-16 Centro Nacional De Investigaciones Cientificas Biomateriales compuestos para implantes óseos
NZ547140A (en) * 2003-10-22 2009-09-25 Encelle Inc Bioactive hydrogel compositions in dehydrated form for regenerating connective tissue
US20050098915A1 (en) * 2003-11-07 2005-05-12 Smith & Nephew Inc. Manufacture of bone graft substitutes
WO2005065079A2 (en) 2003-11-10 2005-07-21 Angiotech International Ag Medical implants and fibrosis-inducing agents
MXPA06005358A (es) 2003-11-14 2006-07-10 Univ Pennsylvania Metodo y aparato para el tratamiento de la osteoartritis, enfermedades de los cartilagos, defectos y lesiones en la cadena humana.
DE10355559A1 (de) 2003-11-21 2005-06-23 Orthogen Ag Transskin
EP1537839A1 (en) 2003-12-02 2005-06-08 Dr. h. c. Robert Mathys Foundation Prosthetic device for cartilage repair
WO2005072656A1 (en) 2004-01-27 2005-08-11 Osteotech, Inc. Stabilized bone graft
US7189263B2 (en) * 2004-02-03 2007-03-13 Vita Special Purpose Corporation Biocompatible bone graft material
US11395865B2 (en) 2004-02-09 2022-07-26 DePuy Synthes Products, Inc. Scaffolds with viable tissue
US7671012B2 (en) 2004-02-10 2010-03-02 Biosurface Engineering Technologies, Inc. Formulations and methods for delivery of growth factor analogs
US7928059B2 (en) 2004-02-24 2011-04-19 Wisconsin Alumni Research Foundation Use of neuropeptides for traumatic cartilage injury
KR101013999B1 (ko) 2004-03-19 2011-02-14 재단법인서울대학교산학협력재단 표면에 골조직 형성 증진 펩타이드가 고정된 차폐막 및임플란트
US20070190101A1 (en) 2004-03-31 2007-08-16 Chunlin Yang Flowable bone grafts
WO2006031388A2 (en) 2004-08-20 2006-03-23 Hyperbranch Medical Technology, Inc. Dentritic polymers, crosslinked gels, and their uses in orthopedic applications
CN101084025A (zh) 2004-09-14 2007-12-05 新加坡科技研究局 多孔生物材料-填充物复合物及其制造方法
CN101060821A (zh) 2004-09-21 2007-10-24 麻省理工学院 梯度支架及其制备方法
US7473678B2 (en) * 2004-10-14 2009-01-06 Biomimetic Therapeutics, Inc. Platelet-derived growth factor compositions and methods of use thereof
US7250550B2 (en) 2004-10-22 2007-07-31 Wright Medical Technology, Inc. Synthetic bone substitute material
WO2006050493A2 (en) 2004-11-03 2006-05-11 The Regents Of The University Of Michigan Biodegradable implant for intertransverse process fusion
WO2007008250A2 (en) 2004-12-07 2007-01-18 Gelwell Biotech Corporation Biomaterials for guided tissue regeneration and target drug delivery
US20060151383A1 (en) 2005-01-12 2006-07-13 Aaf-Mcquay Inc. Pleated corrugated media and method of making
US7621963B2 (en) 2005-04-13 2009-11-24 Ebi, Llc Composite bone graft material
US8268344B2 (en) * 2005-04-27 2012-09-18 The Regents Of The University Of Michigan Particle-containing complex porous materials
EP1909810B2 (en) 2005-06-07 2017-08-23 The Regents of the University of Colorado Inhibitors of serine protease activity and their use in methods and compositions for treatment of graft rejection and promotion of graft survival
US20060287676A1 (en) * 2005-06-15 2006-12-21 Rita Prajapati Method of intra-operative coating therapeutic agents onto sutures, composite sutures and methods of use
WO2007061889A2 (en) 2005-11-17 2007-05-31 Biomimetic Therapeutics, Inc. Maxillofacial bone augmentation using rhpdgf-bb and a biocompatible matrix
US7749555B2 (en) 2006-01-25 2010-07-06 Medtronic, Inc Modification of chemical forces of bone constructs
WO2007090102A2 (en) 2006-01-27 2007-08-09 The Regents Of The University Of California Biomimetic scaffolds
US20070178159A1 (en) 2006-01-30 2007-08-02 Alza Corporation In-Situ Forming Porous Scaffold
EP1991282B1 (en) * 2006-02-09 2013-06-19 BioMimetic Therapeutics, LLC Compositions and methods for treating bone
US7833270B2 (en) 2006-05-05 2010-11-16 Warsaw Orthopedic, Inc Implant depots to deliver growth factors to treat osteoporotic bone
WO2007133451A1 (en) 2006-05-08 2007-11-22 Nuvasive, Inc. Cancellous bone treated with collegenase and essentially free of blood cells
US9161967B2 (en) * 2006-06-30 2015-10-20 Biomimetic Therapeutics, Llc Compositions and methods for treating the vertebral column
CA2656278C (en) 2006-06-30 2016-02-09 Biomimetic Therapeutics, Inc. Compositions and methods for treating rotator cuff injuries
US8106008B2 (en) * 2006-11-03 2012-01-31 Biomimetic Therapeutics, Inc. Compositions and methods for arthrodetic procedures
WO2008086486A1 (en) 2007-01-10 2008-07-17 The Regents Of The University Of Michigan Porous objects having immobilized encapsulated biomolecules
WO2008103690A2 (en) 2007-02-20 2008-08-28 Biomimetic Therapeutics, Inc. Prevention and treatment for osteonecrosis and osteoradionecrosis of the jaw using pdgf and a bone matrix
CN101820895A (zh) 2007-06-04 2010-09-01 生物模拟治疗公司 用于治疗脊柱的组合物和方法
CA2690457C (en) 2007-06-15 2018-02-20 Osteotech, Inc. Bone matrix compositions and methods
WO2009042514A1 (en) 2007-09-25 2009-04-02 Integra Lifesciences Corporation Flowable wound matrix and its preparation and use
KR20110067035A (ko) 2008-09-09 2011-06-20 바이오미메틱 세라퓨틱스, 인크. 건 및 인대 손상의 치료를 위한 혈소판-유래 성장 인자 조성물 및 방법
BRPI0923015A2 (pt) 2008-12-19 2015-12-15 Biomimetic Therapeutics Inc enxertos ósseos com atividade de protease reduzida e métodos de seleção e uso
AU2010221089A1 (en) * 2009-03-05 2011-09-15 Biomimetic Therapeutics, Inc. Platelet-derived growth factor compositions and methods for the treatment of osteochondral defects
MX2017004520A (es) 2014-10-14 2018-03-15 Lynch Samuel Composiciones para tratar heridas.

Similar Documents

Publication Publication Date Title
AU2007320018B2 (en) Methods and collagen products for tissue repair
Lin et al. Biomechanics of tendon injury and repair
JP5484047B2 (ja) 回旋筋腱板傷害を処置するためのpdgf−生体マトリックス組成物および方法
CN105169483B (zh) 一种脱细胞基质凝胶的制备方法及其脱细胞基质凝胶
JP2022065124A (ja) 組織修復のための間葉細胞結合複合材料
JP2012502066A5 (enExample)
KR20110067035A (ko) 건 및 인대 손상의 치료를 위한 혈소판-유래 성장 인자 조성물 및 방법
US10729534B2 (en) Methods of treating a musculoskeletal tissue interface injury using decellularized composite tissue bioscaffolds
ATE288767T1 (de) Penisrekonstruktion mit hilfe von körpergewebe
CN107073174B (zh) 软组织修复用基质及其制造方法
Jetbumpenkul et al. Balanced electrostatic blending approach–An alternative to chemical crosslinking of Thai silk fibroin/gelatin scaffold
CN111346262B (zh) 一种用于促进腱骨愈合的可注射钙磷陶瓷及其制备方法与应用
HUE027146T2 (en) Conjugated polymer material and its uses
Farber et al. Type III acromioclavicular separation: rationale for anatomical reconstruction
Kawai et al. Anterior cruciate ligament reconstruction using chitin‐coated fabrics in a rabbit model
Sawadkar et al. Bioengineering of tendon grafts for tendon defect treatment
KR20260028637A (ko) 회전근 개 및 유도만능줄기세포 유래 건세포를 유효성분으로 포함하는 회전근 개 파열 예방 또는 치료용 약학적 조성물
Cardona-Ramirez Biologic Responses of Ligament and Tendon Graft-Derived Fibroblasts to Clinical Levels of Cyclic Strain
Acker-James et al. Development of a synthetic graft for the purpose of promoting anterior cruciate ligament repair
IT201900013311A1 (it) Nuova composizione riempitiva tissutale
Coleman et al. Tendons and ligaments around the knee: The biology of injury and repair
Sandmann et al. Tissue engineering of the anterior cruciate ligament and meniscus using acellularized scaffolds
宋娜 Multipotent Mesenchymal Stem Cells from Human Subacromial Bursa: Potential for Cell Based Tendon Tissue Engineering
AU2013203295B2 (en) PDGF-biomatrix compositions and methods for treating rotator cuff injuries