JP2009533059A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2009533059A5 JP2009533059A5 JP2009505494A JP2009505494A JP2009533059A5 JP 2009533059 A5 JP2009533059 A5 JP 2009533059A5 JP 2009505494 A JP2009505494 A JP 2009505494A JP 2009505494 A JP2009505494 A JP 2009505494A JP 2009533059 A5 JP2009533059 A5 JP 2009533059A5
- Authority
- JP
- Japan
- Prior art keywords
- hemangio
- cell
- colony forming
- cells
- human
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 210000004027 cell Anatomy 0.000 claims 254
- 238000000034 method Methods 0.000 claims 80
- 210000003958 hematopoietic stem cell Anatomy 0.000 claims 59
- 238000004113 cell culture Methods 0.000 claims 48
- 102100031785 Endothelial transcription factor GATA-2 Human genes 0.000 claims 37
- 101001066265 Homo sapiens Endothelial transcription factor GATA-2 Proteins 0.000 claims 37
- 101001111742 Homo sapiens Rhombotin-2 Proteins 0.000 claims 37
- 102100023876 Rhombotin-2 Human genes 0.000 claims 37
- 210000002889 endothelial cell Anatomy 0.000 claims 30
- 210000001161 mammalian embryo Anatomy 0.000 claims 27
- 102100031573 Hematopoietic progenitor cell antigen CD34 Human genes 0.000 claims 26
- 101000777663 Homo sapiens Hematopoietic progenitor cell antigen CD34 Proteins 0.000 claims 26
- 108090000623 proteins and genes Proteins 0.000 claims 24
- 102000004169 proteins and genes Human genes 0.000 claims 24
- 239000003102 growth factor Substances 0.000 claims 23
- 101000839788 Homo sapiens Homeobox protein Hox-B4 Proteins 0.000 claims 22
- 102100024616 Platelet endothelial cell adhesion molecule Human genes 0.000 claims 21
- 102100040120 Prominin-1 Human genes 0.000 claims 21
- 102100033177 Vascular endothelial growth factor receptor 2 Human genes 0.000 claims 21
- 210000000130 stem cell Anatomy 0.000 claims 20
- 238000011282 treatment Methods 0.000 claims 19
- 102100028404 Homeobox protein Hox-B4 Human genes 0.000 claims 18
- 239000003814 drug Substances 0.000 claims 18
- 210000002242 embryoid body Anatomy 0.000 claims 18
- -1 CD31 Proteins 0.000 claims 17
- 230000003394 haemopoietic effect Effects 0.000 claims 17
- 239000000825 pharmaceutical preparation Substances 0.000 claims 16
- 238000012258 culturing Methods 0.000 claims 15
- 229940079593 drug Drugs 0.000 claims 14
- 239000008194 pharmaceutical composition Substances 0.000 claims 13
- 201000010099 disease Diseases 0.000 claims 12
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 12
- 239000012679 serum free medium Substances 0.000 claims 11
- 230000004069 differentiation Effects 0.000 claims 9
- 210000001671 embryonic stem cell Anatomy 0.000 claims 9
- 102000003951 Erythropoietin Human genes 0.000 claims 8
- 108090000394 Erythropoietin Proteins 0.000 claims 8
- 108010048671 Homeodomain Proteins Proteins 0.000 claims 8
- 102000009331 Homeodomain Proteins Human genes 0.000 claims 8
- 210000003743 erythrocyte Anatomy 0.000 claims 8
- 229940105423 erythropoietin Drugs 0.000 claims 8
- 238000000338 in vitro Methods 0.000 claims 8
- OXCMYAYHXIHQOA-UHFFFAOYSA-N potassium;[2-butyl-5-chloro-3-[[4-[2-(1,2,4-triaza-3-azanidacyclopenta-1,4-dien-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]methanol Chemical compound [K+].CCCCC1=NC(Cl)=C(CO)N1CC1=CC=C(C=2C(=CC=CC=2)C2=N[N-]N=N2)C=C1 OXCMYAYHXIHQOA-UHFFFAOYSA-N 0.000 claims 8
- 238000002360 preparation method Methods 0.000 claims 8
- 230000001332 colony forming effect Effects 0.000 claims 7
- 239000012634 fragment Substances 0.000 claims 7
- 108700028369 Alleles Proteins 0.000 claims 6
- 230000001464 adherent effect Effects 0.000 claims 6
- 125000003275 alpha amino acid group Chemical group 0.000 claims 6
- 210000004369 blood Anatomy 0.000 claims 5
- 239000008280 blood Substances 0.000 claims 5
- 239000003795 chemical substances by application Substances 0.000 claims 5
- 230000001939 inductive effect Effects 0.000 claims 5
- 230000002992 thymic effect Effects 0.000 claims 5
- 102000007350 Bone Morphogenetic Proteins Human genes 0.000 claims 4
- 108010007726 Bone Morphogenetic Proteins Proteins 0.000 claims 4
- 101710149951 Protein Tat Proteins 0.000 claims 4
- 210000001744 T-lymphocyte Anatomy 0.000 claims 4
- 102000036693 Thrombopoietin Human genes 0.000 claims 4
- 108010041111 Thrombopoietin Proteins 0.000 claims 4
- 108010073929 Vascular Endothelial Growth Factor A Proteins 0.000 claims 4
- 102000005789 Vascular Endothelial Growth Factors Human genes 0.000 claims 4
- 108010019530 Vascular Endothelial Growth Factors Proteins 0.000 claims 4
- 210000001772 blood platelet Anatomy 0.000 claims 4
- 229940112869 bone morphogenetic protein Drugs 0.000 claims 4
- 210000003979 eosinophil Anatomy 0.000 claims 4
- 102000054609 human HOXB4 Human genes 0.000 claims 4
- 238000004519 manufacturing process Methods 0.000 claims 4
- 210000001539 phagocyte Anatomy 0.000 claims 4
- 230000026683 transduction Effects 0.000 claims 4
- 238000010361 transduction Methods 0.000 claims 4
- 230000002792 vascular Effects 0.000 claims 4
- 238000005138 cryopreservation Methods 0.000 claims 3
- 230000002062 proliferating effect Effects 0.000 claims 3
- 108091005880 Hemoglobin F Proteins 0.000 claims 2
- 101100018264 Mus musculus Hoxb4 gene Proteins 0.000 claims 2
- 230000020385 T cell costimulation Effects 0.000 claims 2
- 210000001109 blastomere Anatomy 0.000 claims 2
- 210000000625 blastula Anatomy 0.000 claims 2
- 108020001507 fusion proteins Proteins 0.000 claims 2
- 102000037865 fusion proteins Human genes 0.000 claims 2
- 210000003714 granulocyte Anatomy 0.000 claims 2
- 230000001506 immunosuppresive effect Effects 0.000 claims 2
- 230000003993 interaction Effects 0.000 claims 2
- 208000028867 ischemia Diseases 0.000 claims 2
- 210000004698 lymphocyte Anatomy 0.000 claims 2
- 210000005087 mononuclear cell Anatomy 0.000 claims 2
- 210000000440 neutrophil Anatomy 0.000 claims 2
- 229920001184 polypeptide Polymers 0.000 claims 2
- 102000004196 processed proteins & peptides Human genes 0.000 claims 2
- 108090000765 processed proteins & peptides Proteins 0.000 claims 2
- 230000005855 radiation Effects 0.000 claims 2
- 239000000126 substance Substances 0.000 claims 2
- 201000001320 Atherosclerosis Diseases 0.000 claims 1
- 101150013553 CD40 gene Proteins 0.000 claims 1
- PMATZTZNYRCHOR-CGLBZJNRSA-N Cyclosporin A Chemical compound CC[C@@H]1NC(=O)[C@H]([C@H](O)[C@H](C)C\C=C\C)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C1=O PMATZTZNYRCHOR-CGLBZJNRSA-N 0.000 claims 1
- 108010036949 Cyclosporine Proteins 0.000 claims 1
- 102100037362 Fibronectin Human genes 0.000 claims 1
- 108010067306 Fibronectins Proteins 0.000 claims 1
- 208000006011 Stroke Diseases 0.000 claims 1
- 102100040245 Tumor necrosis factor receptor superfamily member 5 Human genes 0.000 claims 1
- 239000000427 antigen Substances 0.000 claims 1
- 108091007433 antigens Proteins 0.000 claims 1
- 102000036639 antigens Human genes 0.000 claims 1
- 210000004204 blood vessel Anatomy 0.000 claims 1
- 210000001185 bone marrow Anatomy 0.000 claims 1
- 210000004556 brain Anatomy 0.000 claims 1
- 210000004413 cardiac myocyte Anatomy 0.000 claims 1
- 229960001265 ciclosporin Drugs 0.000 claims 1
- 238000004440 column chromatography Methods 0.000 claims 1
- 239000003246 corticosteroid Substances 0.000 claims 1
- 229960001334 corticosteroids Drugs 0.000 claims 1
- 229930182912 cyclosporin Natural products 0.000 claims 1
- 210000003414 extremity Anatomy 0.000 claims 1
- 210000001508 eye Anatomy 0.000 claims 1
- 210000004700 fetal blood Anatomy 0.000 claims 1
- 238000007710 freezing Methods 0.000 claims 1
- 230000008014 freezing Effects 0.000 claims 1
- 210000002216 heart Anatomy 0.000 claims 1
- 230000002779 inactivation Effects 0.000 claims 1
- 210000004072 lung Anatomy 0.000 claims 1
- 208000010125 myocardial infarction Diseases 0.000 claims 1
- 230000000242 pagocytic effect Effects 0.000 claims 1
- 210000005259 peripheral blood Anatomy 0.000 claims 1
- 239000011886 peripheral blood Substances 0.000 claims 1
- 230000035755 proliferation Effects 0.000 claims 1
- 210000003491 skin Anatomy 0.000 claims 1
- 210000000329 smooth muscle myocyte Anatomy 0.000 claims 1
- 150000003431 steroids Chemical class 0.000 claims 1
Applications Claiming Priority (13)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US79222406P | 2006-04-14 | 2006-04-14 | |
| US60/792,224 | 2006-04-14 | ||
| US80199306P | 2006-05-19 | 2006-05-19 | |
| US60/801,993 | 2006-05-19 | ||
| US84616306P | 2006-09-20 | 2006-09-20 | |
| US60/846,163 | 2006-09-20 | ||
| US85214206P | 2006-10-16 | 2006-10-16 | |
| US60/852,142 | 2006-10-16 | ||
| US86067606P | 2006-11-22 | 2006-11-22 | |
| US60/860,676 | 2006-11-22 | ||
| US91883207P | 2007-03-19 | 2007-03-19 | |
| US60/918,832 | 2007-03-19 | ||
| PCT/US2007/009106 WO2007120811A2 (en) | 2006-04-14 | 2007-04-13 | Hemangio-colony forming cells |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013061471A Division JP2013126423A (ja) | 2006-04-14 | 2013-03-25 | 血管コロニー形成細胞 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2009533059A JP2009533059A (ja) | 2009-09-17 |
| JP2009533059A5 true JP2009533059A5 (enExample) | 2010-05-27 |
| JP5630781B2 JP5630781B2 (ja) | 2014-11-26 |
Family
ID=38461853
Family Applications (6)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009505494A Active JP5630781B2 (ja) | 2006-04-14 | 2007-04-13 | 血管コロニー形成細胞 |
| JP2013061471A Withdrawn JP2013126423A (ja) | 2006-04-14 | 2013-03-25 | 血管コロニー形成細胞 |
| JP2016015304A Active JP6525899B2 (ja) | 2006-04-14 | 2016-01-29 | 血管コロニー形成細胞 |
| JP2019087461A Pending JP2019165732A (ja) | 2006-04-14 | 2019-05-07 | 血管コロニー形成細胞 |
| JP2022097159A Pending JP2022141641A (ja) | 2006-04-14 | 2022-06-16 | 血管コロニー形成細胞 |
| JP2024122128A Pending JP2024170392A (ja) | 2006-04-14 | 2024-07-29 | 血管コロニー形成細胞 |
Family Applications After (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013061471A Withdrawn JP2013126423A (ja) | 2006-04-14 | 2013-03-25 | 血管コロニー形成細胞 |
| JP2016015304A Active JP6525899B2 (ja) | 2006-04-14 | 2016-01-29 | 血管コロニー形成細胞 |
| JP2019087461A Pending JP2019165732A (ja) | 2006-04-14 | 2019-05-07 | 血管コロニー形成細胞 |
| JP2022097159A Pending JP2022141641A (ja) | 2006-04-14 | 2022-06-16 | 血管コロニー形成細胞 |
| JP2024122128A Pending JP2024170392A (ja) | 2006-04-14 | 2024-07-29 | 血管コロニー形成細胞 |
Country Status (7)
| Country | Link |
|---|---|
| US (5) | US8017393B2 (enExample) |
| EP (6) | EP3712258B1 (enExample) |
| JP (6) | JP5630781B2 (enExample) |
| KR (8) | KR20170102040A (enExample) |
| CN (3) | CN102660495A (enExample) |
| AU (1) | AU2007238660C1 (enExample) |
| WO (1) | WO2007120811A2 (enExample) |
Families Citing this family (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3712258B1 (en) | 2006-04-14 | 2025-01-01 | Astellas Institute for Regenerative Medicine | Hemangio-colony forming cells |
| WO2008067142A2 (en) * | 2006-11-08 | 2008-06-05 | Wisconsin Alumni Research Foundation | In vitro differentiation of hematopoietic cells from primate embryonic stem cells |
| CN101688177A (zh) | 2007-02-12 | 2010-03-31 | 人类起源公司 | 来自贴壁胎盘干细胞的肝细胞和软骨细胞；以及cd34+、cd45-胎盘干细胞富集的细胞群 |
| US9200253B1 (en) * | 2007-08-06 | 2015-12-01 | Anthrogenesis Corporation | Method of producing erythrocytes |
| US8222206B2 (en) * | 2008-03-04 | 2012-07-17 | Taiwan Advance Bio-Pharm Inc. | Method of enhancing the mobilization of hematopoietic stem cells using TAT-HOXB4H |
| CN112280739A (zh) | 2008-05-06 | 2021-01-29 | 安斯泰来再生医药协会 | 用于制备衍生自多能干细胞的去核类红细胞的方法 |
| EP3441462A1 (en) * | 2008-05-06 | 2019-02-13 | Astellas Institute for Regenerative Medicine | Hemangio colony forming cells and non-engrafting hemangio cells |
| US8523851B2 (en) * | 2009-04-17 | 2013-09-03 | Domain Surgical, Inc. | Inductively heated multi-mode ultrasonic surgical tool |
| GB0911060D0 (en) * | 2009-06-26 | 2009-08-12 | Ge Healthcare Uk Ltd | Methods for predicting the toxicity of a chemical |
| CN102725400A (zh) * | 2009-06-29 | 2012-10-10 | 麻省理工学院 | 制造人源化的非人类哺乳动物的方法 |
| MX353489B (es) * | 2009-07-02 | 2018-01-16 | Anthrogenesis Corp | Metodo para producir eritrocitos sin celulas alimentadoras. |
| RU2012127811A (ru) * | 2009-12-04 | 2014-01-10 | Стем Селл Энд Ридженерэйтив Медсин Интернэшнл, Инк. | Способ получения клеток-натуральных киллеров и дендритных клеток из человеческих эмбриональных гемангиобластов, полученных из стволовых клеток |
| KR20190142424A (ko) * | 2009-12-04 | 2019-12-26 | 스템 셀 앤드 리제너러티브 메디신 인터내셔날, 인크. | 기질 없는 조건 하에서 인간 배아줄기세포로부터 기능적 거핵구 및 혈소판의 대규모 생성 |
| US20130078721A1 (en) * | 2010-02-22 | 2013-03-28 | Luc Douay | Cell Culture Medium for the Growth and Differentiation of Cells of the Hematopoietic Lineage |
| EP2547764B1 (en) * | 2010-03-18 | 2019-01-23 | Kyoto University | Method for inducing differentiation of pluripotent stem cells into mesodermal cells |
| WO2012103098A2 (en) * | 2011-01-24 | 2012-08-02 | Immunepath, Inc. | Compositions and methods for treating hematological cytopenias |
| CN102239821B (zh) * | 2011-05-10 | 2013-08-14 | 郑家伟 | 一种人血管瘤动物模型及其构建方法和应用 |
| US8961956B2 (en) | 2011-11-30 | 2015-02-24 | Ocata Therapeutics, Inc. | Mesenchymal stromal cells and uses related thereto |
| KR102108245B1 (ko) | 2011-11-30 | 2020-05-08 | 아스텔라스 인스티튜트 포 리제너러티브 메디슨 | 중간엽 간질 세포 및 이에 관련된 용도 |
| CN104471059B (zh) | 2012-07-12 | 2018-04-17 | 珠海横琴爱姆斯坦生物科技有限公司 | 人胚胎干细胞衍生的间充质样干细胞、方法及其应用 |
| EP3973967A1 (en) | 2012-12-21 | 2022-03-30 | Astellas Institute for Regenerative Medicine | Methods for production of platelets from pluripotent stem cells and compositions thereof |
| WO2014120714A1 (en) | 2013-01-30 | 2014-08-07 | Cornell University | Compositions and methods for the expansion of stem cells |
| DE102013105217A1 (de) * | 2013-05-22 | 2014-11-27 | Illinois Tool Works Inc. | Kompressor zum Erzeugen eines Druckmediums |
| RU2018105986A (ru) * | 2015-07-20 | 2019-08-20 | Анджиокрин Биосайенс, Инк. | Сконструированные эндотелиальные клетки, экспрессирующие фактор транскрипции ets |
| AU2016308818B2 (en) | 2015-08-18 | 2022-04-21 | Astellas Institute For Regenerative Medicine | Clinical formulations |
| EP4520828A3 (en) | 2016-11-15 | 2025-07-09 | The Schepens Eye Research Institute, Inc. | Compositions and methods for the treatment of aberrant angiogenesis |
| EP3824906A1 (en) | 2016-12-21 | 2021-05-26 | Amgen Inc. | Anti-tnf alpha antibody formulations |
| CN109402047A (zh) * | 2017-09-18 | 2019-03-01 | 武汉原生原代生物医药科技有限公司 | 促组织粘附和生长生物粘合剂及其制备方法和用途 |
| JP7416700B2 (ja) * | 2017-11-14 | 2024-01-17 | ザ スキーペンズ アイ リサーチ インスティチュート インコーポレイテッド | 増殖性硝子体網膜症および上皮間葉転換と関連付けられる状態の治療のためのｒｕｎｘ１阻害の方法 |
| KR102167641B1 (ko) * | 2018-08-27 | 2020-10-19 | 주식회사 사이루스 | 에리스로포이에틴 유래 펩티드를 함유하는 세포증식 촉진용 조성물 |
| AU2020266117A1 (en) * | 2019-04-27 | 2021-12-16 | Figene, Llc | Selection of fibroblast donors for optimization of allogeneic fibroblast-mediated regeneration |
| US20220280572A1 (en) * | 2019-08-28 | 2022-09-08 | Astellas Institute For Regenerative Medicine | Methods of treating vascular diseases |
| MX2022002418A (es) | 2019-08-28 | 2022-03-22 | Astellas Inst For Regenerative Medicine | Composiciones y metodos de tratamiento de enfermedades vasculares. |
| US20210192477A1 (en) * | 2019-12-24 | 2021-06-24 | Up N' Go | App-less restaurant processing system using mobile devices and offering check splitting |
| CN112940097A (zh) * | 2021-02-08 | 2021-06-11 | 华东理工大学 | Survivin多点突变体重组蛋白及其应用 |
| EP4558154A1 (en) | 2022-07-18 | 2025-05-28 | Astellas Institute for Regenerative Medicine | Methods of treating brain injury |
Family Cites Families (138)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5399346A (en) | 1989-06-14 | 1995-03-21 | The United States Of America As Represented By The Department Of Health And Human Services | Gene therapy |
| US5128259A (en) * | 1989-10-27 | 1992-07-07 | Hahnemann University | Factor-dependent hematopoietic cell line exhibiting epo-induced erythrocyte maturation |
| US5635387A (en) | 1990-04-23 | 1997-06-03 | Cellpro, Inc. | Methods and device for culturing human hematopoietic cells and their precursors |
| US7153684B1 (en) | 1992-10-08 | 2006-12-26 | Vanderbilt University | Pluripotential embryonic stem cells and methods of making same |
| CA2169292C (en) | 1993-08-12 | 2010-11-23 | E. Edward Baetge | Improved compositions and methods for the delivery of biologically active molecules using genetically altered cells contained in biocompatible immunoisolatory capsules |
| US5599705A (en) * | 1993-11-16 | 1997-02-04 | Cameron; Robert B. | In vitro method for producing differentiated universally compatible mature human blood cells |
| EP0739412B1 (en) | 1993-12-23 | 2002-02-27 | Infigen, Inc. | ungulate EMBRYONIC STEM CELLS AS NUCLEAR DONORS AND NUCLEAR TRANSFER TECHNIQUES TO PRODUCE CHIMERIC AND TRANSGENIC ANIMALS |
| US5914268A (en) * | 1994-11-21 | 1999-06-22 | National Jewish Center For Immunology & Respiratory Medicine | Embryonic cell populations and methods to isolate such populations |
| US5874301A (en) * | 1994-11-21 | 1999-02-23 | National Jewish Center For Immunology And Respiratory Medicine | Embryonic cell populations and methods to isolate such populations |
| US6063593A (en) | 1996-11-12 | 2000-05-16 | University Of Southern California University Park Campus | TGFβ1 responsive bone marrow derived cells to express a recombinant protein |
| WO1998033891A1 (en) | 1997-01-31 | 1998-08-06 | Hemosol Inc. | Method for the production of selected lymphocytes |
| WO1998053048A1 (en) | 1997-05-21 | 1998-11-26 | The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Methods and compositions for making dendritic cells from expanded populations of monocytes and for activating t cells |
| US6429012B1 (en) | 1997-10-06 | 2002-08-06 | Viacell, Inc. | Cell population containing non-fetal hemangioblasts and method for producing same |
| US6361998B1 (en) | 1998-06-25 | 2002-03-26 | Hemosol Inc. | Efficient culture of stem cells for the production of hemoglobin |
| EP1270719A3 (en) | 1998-08-24 | 2003-06-25 | Viacell, Inc. | Cell population containing non-fetal hemangioblasts and method for producing same |
| IL129966A (en) | 1999-05-14 | 2009-12-24 | Technion Res & Dev Foundation | ISOLATED HUMAN EMBRYOID BODIES (hEB) DERIVED FROM HUMAN EMBRYONIC STEM CELLS |
| BR0014864A (pt) | 1999-10-15 | 2002-11-19 | Advanced Cell Tech Inc | Métodos de produzir células progenitoras diferenciadas e células tronco embriÈnicas defeituosas em linhagem |
| WO2001036589A2 (en) | 1999-11-17 | 2001-05-25 | University Of Rochester | Human ex vivo immune system |
| WO2001050848A2 (en) * | 2000-01-07 | 2001-07-19 | Oregon Health And Science University | Clonal propagation of primate offspring by embryo splitting |
| EP1248834A4 (en) * | 2000-01-21 | 2004-03-17 | Univ Johns Hopkins | CELLS FROM HUMAN EMBRYOID BODIES |
| US6602711B1 (en) * | 2000-02-21 | 2003-08-05 | Wisconsin Alumni Research Foundation | Method of making embryoid bodies from primate embryonic stem cells |
| AU8617301A (en) * | 2000-08-01 | 2002-02-13 | Yissum Res Dev Co | Directed differentiation of embryonic cells |
| EP1364197B1 (en) | 2001-01-29 | 2010-04-14 | Ivan N. Rich | ATP-based assay for the determination of the proliferation status of hematopoietic stem and progenitor cells |
| JP3660601B2 (ja) | 2001-03-30 | 2005-06-15 | 独立行政法人科学技術振興機構 | 胚性幹細胞からの神経幹細胞、運動ニューロン及びｇａｂａ作動性ニューロンの製造法 |
| WO2002078449A2 (en) | 2001-04-02 | 2002-10-10 | Advanced Cell Technology, Inc. | Method for facilitating the production of differentiated cell types and tissues from embryonic and adult pluripotent and multipotent cells |
| KR20020083634A (ko) | 2001-04-27 | 2002-11-04 | 크레아젠 주식회사 | 수지상 세포를 포함하는 자가면역 질환의 치료용 약제학적조성물 및 이를 이용한 치료방법 |
| US6861504B2 (en) | 2001-05-03 | 2005-03-01 | Cbr, Inc. | Compounds and methods for the modulation of CD154 |
| EP1393066A4 (en) * | 2001-05-15 | 2006-01-25 | Rappaport Family Inst For Res | INSULIN-PRODUCING CELLS DERIVED FROM HUMAN EMBRYONIC STEM CELLS |
| WO2003038072A1 (en) | 2001-10-31 | 2003-05-08 | Universite Libre De Bruxelles | Generation and use of new types of dendritic cells |
| CA2465173C (en) | 2001-11-02 | 2010-04-20 | Wisconsin Alumni Research Foundation | Endothelial cells derived from primate embryonic stem cells |
| WO2003046141A2 (en) * | 2001-11-26 | 2003-06-05 | Advanced Cell Technology, Inc. | Methods for making and using reprogrammed human somatic cell nuclei and autologous and isogenic human stem cells |
| EP1463803B1 (en) * | 2001-12-07 | 2018-02-14 | Asterias Biotherapeutics, Inc. | Hematopoietic cells from human embryonic stem cells |
| WO2003060083A2 (en) | 2002-01-15 | 2003-07-24 | Advanced Cell Technology, Inc. | Cloning b and t lymphocytes |
| US20040091936A1 (en) | 2002-05-24 | 2004-05-13 | Michael West | Bank of stem cells for producing cells for transplantation having HLA antigens matching those of transplant recipients, and methods for making and using such a stem cell bank |
| US20040052771A1 (en) | 2002-07-12 | 2004-03-18 | Lim Sai Kiang | Hemangioblast progenitor cells |
| AU2003248609A1 (en) | 2002-07-12 | 2004-02-02 | Agency For Science, Technology And Research | Hemangioblast progenitor cells |
| WO2004024875A2 (en) | 2002-09-13 | 2004-03-25 | The Board Of Trustees Of The Leland Stanford Junior University | Mammalian megakaryocyte progenitor cell |
| WO2004029200A2 (en) * | 2002-09-26 | 2004-04-08 | Children's Medical Center Corporation | Method of enhancing proliferation and/or hematopoietic differentiation of stem cells |
| WO2004029231A1 (en) * | 2002-09-26 | 2004-04-08 | Institut National De La Sante Et De La Recherche Medicale | Compositions and methods for amplification of human stem cells |
| AU2003269379A1 (en) | 2002-10-31 | 2004-05-25 | Pfizer Products Inc. | Suspension method for producing embryoid bodies, and compositions and methods related thereto |
| AU2003287521A1 (en) | 2002-11-06 | 2004-06-03 | Carlos J. Piniella | Pluripotent cells from monocytes, and methods of making and using pluripotent cells |
| WO2004050826A2 (en) | 2002-11-29 | 2004-06-17 | Technion Research & Development Foundation Ltd. | Method of dynamically culturing embryonic stem cells |
| US20050032210A1 (en) | 2003-03-18 | 2005-02-10 | Kirin Beer Kabushiki Kaisha | Method of preparing immuno-regulatory dendritic cells and the use thereof |
| US20040229350A1 (en) * | 2003-05-12 | 2004-11-18 | Nikolai Strelchenko | Morula derived embryonic stem cells |
| EP1627913A4 (en) | 2003-05-28 | 2007-08-22 | Riken | MESENCHYMAL STEM CELLS |
| WO2005005621A2 (en) | 2003-07-08 | 2005-01-20 | Axiogenesis Ag | NOVEL METHOD FOR THE PREPARATION OF EMBRYOID BODIES (EBs) AND USES THEREOF |
| US20050054100A1 (en) | 2003-09-08 | 2005-03-10 | Rennard Stephen I. | Methods for fibroblast differentiation |
| WO2005040391A1 (en) | 2003-10-27 | 2005-05-06 | Murdoch Childrens Research Institute | Compositions and methods for differentiating stem cells |
| US20070141703A1 (en) * | 2003-11-19 | 2007-06-21 | Stanley Edouard G | Methods for producing blood products from pluripotent cells in cell culture |
| US20080026460A1 (en) | 2006-06-20 | 2008-01-31 | Palecek Sean P | Method for culturing stem cells |
| CN1286970C (zh) | 2003-12-30 | 2006-11-29 | 上海伯瑞生物技术发展有限公司 | 由脐血cd34+细胞体外诱导生成巨核细胞的方法 |
| KR100535326B1 (ko) | 2004-01-20 | 2005-12-09 | 한국생명공학연구원 | 줄기 세포로부터 자연살해 세포로의 분화 조절용 유전자를유효성분으로 포함하는 분화 조절제 |
| CA2554094A1 (en) * | 2004-02-09 | 2005-08-25 | Indiana University Research And Technology Corporation | Isolation, expansion and use of clonogenic endothelial progenitor cells |
| EP1735429A4 (en) | 2004-03-31 | 2008-06-11 | Newlink Genetics Corp | METHOD AND COMPOSITIONS FOR OBTAINING EMBRYONAL STEM CELLS OF ABSTINENT HEMATOPOETIC STEM CELLS AND USES THEREOF |
| EP1743023A1 (en) | 2004-05-07 | 2007-01-17 | Wisconsin Alumni Research Foundation | Method of forming mesenchymal stem cells from embryonic stem cells |
| WO2006001954A2 (en) | 2004-05-20 | 2006-01-05 | Puget Sound Blood Center And Program | Methods for promoting the formation of platelets and for treating blood and bone marrow disorders |
| EP1753859B1 (en) | 2004-06-04 | 2014-07-30 | Université Pierre et Marie Curie (Paris 6) | A method for producing red blood cells |
| CA2571849A1 (en) | 2004-06-24 | 2006-01-05 | Dnavec Research Inc. | Anticancer agent containing dendritic cell having rna virus transferred thereinto |
| EP1784481A1 (en) | 2004-08-25 | 2007-05-16 | Technion Research And Development Foundation, Ltd. | Methods of generating embryoid bodies using three dimensional scaffolds |
| EP1799810A2 (en) | 2004-10-12 | 2007-06-27 | Technion Research & Development Foundation Ltd. | Isolated primate embryonic cells and methods of generating and using same |
| CN101052710A (zh) | 2004-11-01 | 2007-10-10 | 威斯康星校友研究基金会 | 来自干细胞的血小板 |
| WO2006050330A2 (en) | 2004-11-01 | 2006-05-11 | Wisconsin Alumni Research Foundation | Platelets from stem cells |
| US7893315B2 (en) * | 2004-11-04 | 2011-02-22 | Advanced Cell Technology, Inc. | Derivation of embryonic stem cells and embryo-derived cells |
| US7558394B2 (en) | 2005-02-14 | 2009-07-07 | Insound Medical, Inc. | Systems and methods for in situ cerumen removal from hearing devices |
| US20080166751A1 (en) | 2005-02-23 | 2008-07-10 | Takayuki Asahara | Method of Analyzing Dynamics in the Differentiation of Vascular Endothelial Progenitor Cells |
| WO2006090882A1 (ja) | 2005-02-23 | 2006-08-31 | Foundation For Biomedical Research And Innovation | 血管内皮前駆細胞の生体外増幅方法 |
| CA2601197C (en) | 2005-03-17 | 2017-06-06 | Ucl Biomedica Plc | Method |
| JP5020935B2 (ja) | 2005-04-08 | 2012-09-05 | アルゴス セラピューティクス，インコーポレイティド | 樹状細胞組成物および方法 |
| CA2610243C (en) * | 2005-06-01 | 2016-11-15 | Wisconsin Alumni Research Foundation | Method of forming dendritic cells from embryonic stem cells |
| WO2007005595A1 (en) | 2005-07-05 | 2007-01-11 | The New England Medical Center Hospitals, Inc. | Pregnancy-associated progenitor cells |
| US9121008B2 (en) | 2005-08-31 | 2015-09-01 | University Of Utah Research Foundation | Development of natural killer cells and functional natural killer cell lines |
| BRPI0617084A2 (pt) | 2005-09-02 | 2011-07-12 | Agency Science Tech & Res | método, linhagem de célula progenitora, célula diferenciada e método para gerar uma célula diferenciada de uma célula-tronco (es) embrionária |
| EP1789435B1 (en) | 2005-09-12 | 2010-02-24 | Industry Foundation of Chonnam National University | A method for production of mature natural killer cell |
| JP2007089432A (ja) | 2005-09-27 | 2007-04-12 | Reprocell Inc | 幹細胞由来血小板産生増加法 |
| PT1941027E (pt) | 2005-09-28 | 2014-10-09 | Ipd Therapeutics B V | Métodos e meios para proliferação de células estaminais e subsequente geração e expansão de células progenitoras, bem como produção de células efectoras como produtos terapêuticos clínicos |
| US20070128727A1 (en) | 2005-11-08 | 2007-06-07 | Kraemer Fredric B | Methods for differentiation of embryonic stem cells |
| EP1981970A4 (en) | 2006-01-11 | 2009-10-21 | Technion Res & Dev Foundation | TISSUE CONSTRUCTION TISSUE TREATMENT DERIVED FROM A HUMAN EMBRYONIC STEM CELL |
| WO2007095064A2 (en) * | 2006-02-09 | 2007-08-23 | Wisconsin Alumni Research Foundation | ERYTHROID CELLS PRODUCING ADULT-TYPE β-HEMOGLOBIN GENERATED FROM HUMAN EMBRYONIC STEM CELLS |
| CN101045915A (zh) | 2006-03-29 | 2007-10-03 | 旭日干 | 一种卵母细胞生发泡移植技术 |
| CN101045914A (zh) | 2006-03-29 | 2007-10-03 | 中国人民解放军军事医学科学院野战输血研究所 | 体外诱导造血干/祖细胞分化为成熟红细胞的方法与应用 |
| EP3712258B1 (en) | 2006-04-14 | 2025-01-01 | Astellas Institute for Regenerative Medicine | Hemangio-colony forming cells |
| AU2013201444B2 (en) | 2006-04-14 | 2015-01-22 | Astellas Institute For Regenerative Medicine | Hemangio-colony forming cells |
| NZ572842A (en) | 2006-04-14 | 2012-01-12 | Advanced Cell Tech Inc | Hemangio-colony forming cells |
| WO2007122233A1 (en) | 2006-04-25 | 2007-11-01 | Vrije Universiteit Brussel | Preparation of mesenchymal progenitor cells, particularly osteogenic progenitor cells |
| US20070298496A1 (en) * | 2006-06-23 | 2007-12-27 | Hung-Chih Kuo | Method of deriving pluripotent stem cells from a single blastomere |
| EP2054506A1 (en) | 2006-08-15 | 2009-05-06 | Agency for Science, Technology and Research | Mesenchymal stem cell conditioned medium |
| WO2008021475A2 (en) | 2006-08-16 | 2008-02-21 | The General Hospital Corporation | Compositions and methods for hematopoietic stem cell expansion or for modulating angiogenesis |
| US20080081370A1 (en) | 2006-09-28 | 2008-04-03 | Peiman Hematti | Directed differentiation of human embryonic stem cells into mesenchymal/stromal cells |
| WO2008067142A2 (en) * | 2006-11-08 | 2008-06-05 | Wisconsin Alumni Research Foundation | In vitro differentiation of hematopoietic cells from primate embryonic stem cells |
| EP2088190A4 (en) | 2006-11-09 | 2011-01-05 | Japan Government | METHOD FOR THE CULTURE AND PASSING OF AN EMBRYONAL PRIMATIVE STEM CELL AND METHOD FOR INDUCING THE DIFFERENTIATION OF THE EMBRYONAL STEM CELL |
| DE102006054041B3 (de) | 2006-11-16 | 2008-05-08 | Pierburg Gmbh | Regelvorrichtung für eine Verbrennungskraftmaschine |
| US20100184212A1 (en) | 2007-05-30 | 2010-07-22 | Steven Stice | Human embryonic stem cell derived mesoderm-like epithelium transitions to mesenchymal progenitor cells |
| JP2008307007A (ja) | 2007-06-15 | 2008-12-25 | Bayer Schering Pharma Ag | 出生後のヒト組織由来未分化幹細胞から誘導したヒト多能性幹細胞 |
| WO2008151386A1 (en) | 2007-06-15 | 2008-12-18 | Australian Stem Cell Centre Ltd | Megakaryocyte differentiation |
| WO2008151390A1 (en) | 2007-06-15 | 2008-12-18 | Australian Stem Cell Centre Ltd | Differentiation of human embryonic stem cells |
| US7615374B2 (en) | 2007-09-25 | 2009-11-10 | Wisconsin Alumni Research Foundation | Generation of clonal mesenchymal progenitors and mesenchymal stem cell lines under serum-free conditions |
| AU2008307633C1 (en) | 2007-09-28 | 2015-04-30 | Celularity Inc. | Tumor suppression using human placental perfusate and human placenta-derived intermediate natural killer cells |
| US20120003738A1 (en) | 2007-10-04 | 2012-01-05 | University Hospitals Of Cleveland | Method For Amplification And Functional Enhancment Of Blood Derived Progenitor Cells Using A Closed Culture System |
| US8501474B2 (en) | 2007-10-15 | 2013-08-06 | Technion Research & Development Foundation Limited | Methods of generating embryoid bodies and uses of same |
| US20100304480A1 (en) | 2007-10-19 | 2010-12-02 | Goodell Margaret A | Hematopoietic Fingerprints: Methods of Use |
| US9683232B2 (en) | 2007-12-10 | 2017-06-20 | Kyoto University | Efficient method for nuclear reprogramming |
| WO2009104825A1 (en) | 2008-02-18 | 2009-08-27 | Kaist | Method for inducing the defferentiation of embryonic stem cells into hemangioblast |
| WO2009119105A1 (ja) | 2008-03-28 | 2009-10-01 | 国立大学法人東京大学 | ＧＰＩｂα＋ＧＰＶ＋ＧＰＶＩ＋血小板のインビトロ調製法 |
| EP2277995B1 (en) | 2008-04-01 | 2017-09-27 | The University of Tokyo | Method for preparation of platelet from ips cell |
| EP3441462A1 (en) | 2008-05-06 | 2019-02-13 | Astellas Institute for Regenerative Medicine | Hemangio colony forming cells and non-engrafting hemangio cells |
| CN112280739A (zh) | 2008-05-06 | 2021-01-29 | 安斯泰来再生医药协会 | 用于制备衍生自多能干细胞的去核类红细胞的方法 |
| WO2009136283A2 (en) | 2008-05-08 | 2009-11-12 | Coretherapix Slu | Multipotent adult stem cell population |
| CN102144028B (zh) | 2008-09-03 | 2017-12-26 | 中胚有限公司 | 造血前体的扩增 |
| US8956867B2 (en) | 2008-11-07 | 2015-02-17 | Wisconsin Alumni Research Foundation | Method for culturing stem cells |
| KR101720961B1 (ko) | 2009-02-27 | 2017-03-29 | 셀룰러 다이내믹스 인터내셔널, 인코포레이티드 | 다능성 세포의 분화 |
| US20120148546A1 (en) | 2009-08-17 | 2012-06-14 | Technion Research & Development Foundation Ltd. | Pericyte progenitor cells and methods of generating and using same |
| KR101193541B1 (ko) | 2009-08-24 | 2012-10-22 | 한국과학기술원 | 인간 배아줄기세포에서 중간엽 줄기세포로 분화시키는 방법 |
| WO2011026221A1 (en) | 2009-09-01 | 2011-03-10 | Mcmaster University | Methods of culturing embryoid bodies |
| KR101135636B1 (ko) | 2009-10-27 | 2012-04-17 | 서울대학교산학협력단 | 인간 만능줄기세포로부터 중배엽 줄기세포를 생산하는 방법 및 이에 의해 생성된 중배엽 줄기세포 |
| RU2012127811A (ru) | 2009-12-04 | 2014-01-10 | Стем Селл Энд Ридженерэйтив Медсин Интернэшнл, Инк. | Способ получения клеток-натуральных киллеров и дендритных клеток из человеческих эмбриональных гемангиобластов, полученных из стволовых клеток |
| KR20190142424A (ko) | 2009-12-04 | 2019-12-26 | 스템 셀 앤드 리제너러티브 메디신 인터내셔날, 인크. | 기질 없는 조건 하에서 인간 배아줄기세포로부터 기능적 거핵구 및 혈소판의 대규모 생성 |
| EP2529009A4 (en) | 2010-01-28 | 2013-11-13 | Univ Queensland | METHOD OF STEM CELL DIFFERENTIATION |
| KR101330327B1 (ko) | 2010-05-07 | 2013-11-14 | 한국생명공학연구원 | 줄기세포로부터 생성된 배아체를 대량 증식 및 유지하는 방법 |
| US10214722B2 (en) | 2010-09-07 | 2019-02-26 | Technion Research & Development Foundation Limited | Methods for expanding and maintaining human pluripotent stem cells (PSCs) in an undifferentiated state in a single cell suspension culture |
| WO2012129109A2 (en) | 2011-03-18 | 2012-09-27 | New York Blood Center, Inc. | Megakaryocyte and platelet production from stem cells |
| WO2013055297A1 (en) | 2011-10-13 | 2013-04-18 | Singapore Health Services Pte Ltd | Method for preparing mesenchymal stem cell-like cells and cardiomyocyte-like cells |
| KR102108245B1 (ko) * | 2011-11-30 | 2020-05-08 | 아스텔라스 인스티튜트 포 리제너러티브 메디슨 | 중간엽 간질 세포 및 이에 관련된 용도 |
| KR101477016B1 (ko) | 2012-01-19 | 2014-12-29 | (주)차바이오텍 | 인간 배아줄기세포 유래 혈관주위 전구세포의 제조방법 및 이를 포함하는 세포치료 조성물 |
| EP2872619B1 (en) | 2012-07-11 | 2018-02-14 | Imstem Biotechnology Inc. | Mesenchymal-like stem cells derived from human embryonic stem cells, methods and uses thereof |
| CN104471059B (zh) | 2012-07-12 | 2018-04-17 | 珠海横琴爱姆斯坦生物科技有限公司 | 人胚胎干细胞衍生的间充质样干细胞、方法及其应用 |
| WO2014138485A1 (en) | 2013-03-08 | 2014-09-12 | Irm Llc | Ex vivo production of platelets from hematopoietic stem cells and the product thereof |
| CA3141731A1 (en) | 2013-03-13 | 2014-10-09 | Wisconsin Alumni Research Foundation | Methods and materials for hematoendothelial differentiation of human pluripotent stem cells under defined conditions |
| WO2014146057A2 (en) | 2013-03-15 | 2014-09-18 | Cmr Technologies, Llc | Mesenchymal stem cells |
| US20140271616A1 (en) | 2013-03-15 | 2014-09-18 | The Board Of Trustees Of The Leland Stanford Junior University | Compositions And Methods For Mesenchymal And/Or Chondrogenic Differentiation Of Stem Cells |
| KR101669124B1 (ko) | 2013-07-11 | 2016-10-25 | 서울대학교병원 | 인간 배아줄기세포에서 유래된 중간엽 줄기세포를 유효성분으로 함유하는 간섬유화 또는 간경화 예방 및 치료용 조성물 |
| WO2015179301A1 (en) | 2014-05-19 | 2015-11-26 | Eleftherios Papoutsakis | Megakaryocytic particles and microparticles for cell therapy & fate modification of stem and progenitor cells |
| EP3942931A1 (en) | 2014-06-10 | 2022-01-26 | Biomatrica, INC. | Stabilization of thrombocytes at ambient temperatures |
| JP6459257B2 (ja) | 2014-07-08 | 2019-01-30 | 富士ゼロックス株式会社 | 画像形成装置 |
| AU2016242823A1 (en) | 2015-03-30 | 2017-09-21 | Jeffrey Thomas Loh | Methods for producing modified red blood cell compositions, compositions and uses thereof |
| CA3017772C (en) | 2016-03-16 | 2023-02-21 | Cynata Therapeutics Limited | Colony forming medium and use thereof |
| US20190161726A1 (en) | 2016-07-29 | 2019-05-30 | Daikin Industries, Ltd. | Differentiated cell production method and culture bag used therefor |
| CN109666630A (zh) | 2017-10-17 | 2019-04-23 | 澳门大学 | 多能干细胞分化为间充质干细胞的方法及其培养基和应用 |
| EP3813852B1 (en) | 2018-05-02 | 2025-07-30 | The Trustees of Columbia University in the City of New York | Methods to induce terminal differentiation in stem cells by interfering with dna replication, methods of inducing pancreatic differentiation, and differentiated cells obtained thereof |
-
2007
- 2007-04-13 EP EP20169139.1A patent/EP3712258B1/en active Active
- 2007-04-13 CN CN2012101320883A patent/CN102660495A/zh active Pending
- 2007-04-13 EP EP11155495A patent/EP2377924A1/en not_active Withdrawn
- 2007-04-13 EP EP11155482A patent/EP2426197A1/en not_active Withdrawn
- 2007-04-13 KR KR1020177023744A patent/KR20170102040A/ko not_active Ceased
- 2007-04-13 KR KR1020227014323A patent/KR102651433B1/ko active Active
- 2007-04-13 AU AU2007238660A patent/AU2007238660C1/en active Active
- 2007-04-13 CN CNA2007800218226A patent/CN101528915A/zh active Pending
- 2007-04-13 WO PCT/US2007/009106 patent/WO2007120811A2/en not_active Ceased
- 2007-04-13 KR KR1020247043162A patent/KR20250008978A/ko active Pending
- 2007-04-13 KR KR1020237033022A patent/KR20230145494A/ko not_active Ceased
- 2007-04-13 CN CN201610328018.3A patent/CN106434527A/zh active Pending
- 2007-04-13 KR KR1020087027950A patent/KR20090045886A/ko not_active Ceased
- 2007-04-13 KR KR1020147033315A patent/KR20140146224A/ko not_active Ceased
- 2007-04-13 US US11/787,262 patent/US8017393B2/en active Active
- 2007-04-13 EP EP07755391A patent/EP2013331A2/en not_active Ceased
- 2007-04-13 EP EP11155500A patent/EP2377925A1/en not_active Withdrawn
- 2007-04-13 EP EP11155399A patent/EP2377923A1/en not_active Withdrawn
- 2007-04-13 KR KR1020217007639A patent/KR102510368B1/ko active Active
- 2007-04-13 KR KR1020197035159A patent/KR102230288B1/ko active Active
- 2007-04-13 JP JP2009505494A patent/JP5630781B2/ja active Active
-
2011
- 2011-07-26 US US13/190,988 patent/US20120027731A1/en not_active Abandoned
-
2013
- 2013-03-25 JP JP2013061471A patent/JP2013126423A/ja not_active Withdrawn
-
2015
- 2015-09-29 US US14/869,561 patent/US9938500B2/en active Active
-
2016
- 2016-01-29 JP JP2016015304A patent/JP6525899B2/ja active Active
-
2018
- 2018-02-22 US US15/902,817 patent/US11566228B2/en active Active
-
2019
- 2019-05-07 JP JP2019087461A patent/JP2019165732A/ja active Pending
-
2022
- 2022-06-16 JP JP2022097159A patent/JP2022141641A/ja active Pending
- 2022-12-13 US US18/080,134 patent/US20230313141A1/en active Pending
-
2024
- 2024-07-29 JP JP2024122128A patent/JP2024170392A/ja active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2009533059A5 (enExample) | ||
| EP2086556B1 (en) | Mixed cell populations for tissue repair and separation technique for cell processing | |
| KR102505009B1 (ko) | 치료 용도를 위한 푸코실화된 세포의 제조 및 동결보존 | |
| RU2691062C2 (ru) | Перепрограммирование эндотелия человека в гемопоэтических предшественников множественных линий дифференцировки с использованием определенных факторов | |
| JP2019165732A5 (enExample) | ||
| US10463698B2 (en) | Compositions and methods for expansion of embryonic hematopoietic stem cells | |
| JP6643999B2 (ja) | 細胞培養方法 | |
| JP2010508818A5 (enExample) | ||
| JP2021052774A (ja) | 新しい免疫調節細胞およびその製造方法 | |
| AU2018346818B2 (en) | Expansion and use of expanded NK cell fractions | |
| JP2017531448A (ja) | Ｔ細胞前駆細胞を生成するための方法 | |
| CN112135901A (zh) | 获得源自胸腺组织的调节性t细胞的方法及所述细胞作为细胞免疫疗法在免疫系统失调中的用途 | |
| US20170224736A1 (en) | Method and apparatus for recovery of umbilical cord tissue derived regenerative cells and uses thereof | |
| JP2010533486A (ja) | 幹細胞の生体外増殖培地 | |
| JP7757295B2 (ja) | 血小板由来ミトコンドリア治療及び多能性細胞の生成方法 | |
| US20230383257A1 (en) | Production of megakaryocytes and platelets in a co-culture system | |
| US20250127816A1 (en) | Systems and methods for growing mitochondria and coating thereof | |
| AU2013206071B2 (en) | Mixed Cell Populations for Tissue Repair and Separation Technique for Cell Processing | |
| AU2016216704A1 (en) | Mixed Cell Populations for Tissue Repair and Separation Technique for Cell Processing | |
| HK40005831A (en) | Expansion and use of expanded nk cell fractions | |
| Mukonoweshuro | Immunogenicity of allogeneic mouse mesenchymal stem cells (MSC) |