JP2009530410A5 - - Google Patents
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- Publication number
- JP2009530410A5 JP2009530410A5 JP2009501610A JP2009501610A JP2009530410A5 JP 2009530410 A5 JP2009530410 A5 JP 2009530410A5 JP 2009501610 A JP2009501610 A JP 2009501610A JP 2009501610 A JP2009501610 A JP 2009501610A JP 2009530410 A5 JP2009530410 A5 JP 2009530410A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- heteroaryl
- saturated
- aryl
- heterocyclyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 0 C*1nn*c(N)c1I* Chemical compound C*1nn*c(N)c1I* 0.000 description 2
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US78546006P | 2006-03-24 | 2006-03-24 | |
| US60/785,460 | 2006-03-24 | ||
| PCT/US2007/007444 WO2007117381A2 (en) | 2006-03-24 | 2007-03-23 | 2 -aminopyridine analogs as glucokinase activators |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013171956A Division JP2013245220A (ja) | 2006-03-24 | 2013-08-22 | グルコキナーゼアクチベーターとしての２−アミノピリジンアナログ |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2009530410A JP2009530410A (ja) | 2009-08-27 |
| JP2009530410A5 true JP2009530410A5 (enExample) | 2011-04-28 |
| JP5377284B2 JP5377284B2 (ja) | 2013-12-25 |
Family
ID=38542984
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009501610A Expired - Fee Related JP5377284B2 (ja) | 2006-03-24 | 2007-03-23 | グルコキナーゼアクチベーターとしての２−アミノピリジンアナログ |
| JP2013171956A Withdrawn JP2013245220A (ja) | 2006-03-24 | 2013-08-22 | グルコキナーゼアクチベーターとしての２−アミノピリジンアナログ |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013171956A Withdrawn JP2013245220A (ja) | 2006-03-24 | 2013-08-22 | グルコキナーゼアクチベーターとしての２−アミノピリジンアナログ |
Country Status (25)
| Country | Link |
|---|---|
| US (3) | US8022223B2 (enExample) |
| EP (2) | EP2543667B1 (enExample) |
| JP (2) | JP5377284B2 (enExample) |
| KR (1) | KR101440634B1 (enExample) |
| CN (1) | CN101437816B (enExample) |
| AU (1) | AU2007235558B2 (enExample) |
| BR (1) | BRPI0709171A2 (enExample) |
| CA (1) | CA2647208C (enExample) |
| DK (1) | DK2013204T3 (enExample) |
| ES (1) | ES2536547T3 (enExample) |
| HR (1) | HRP20150347T1 (enExample) |
| IL (1) | IL194160A (enExample) |
| MX (1) | MX2008012168A (enExample) |
| MY (1) | MY148985A (enExample) |
| NZ (1) | NZ571997A (enExample) |
| PL (1) | PL2013204T3 (enExample) |
| PT (1) | PT2013204E (enExample) |
| RS (1) | RS53981B1 (enExample) |
| RU (1) | RU2457207C2 (enExample) |
| SG (1) | SG170775A1 (enExample) |
| SI (1) | SI2013204T1 (enExample) |
| TW (1) | TWI393718B (enExample) |
| UA (1) | UA103746C2 (enExample) |
| WO (1) | WO2007117381A2 (enExample) |
| ZA (1) | ZA200809017B (enExample) |
Families Citing this family (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RS53981B1 (sr) | 2006-03-24 | 2015-10-30 | Array Biopharma Inc. | Analozi 2-aminopiridina kao aktivatori glukokinaze |
| US8431713B2 (en) * | 2007-01-24 | 2013-04-30 | Array Biopharma, Inc. | 2-aminopyridine derivatives as glucokinase activators |
| JP5450108B2 (ja) * | 2007-03-23 | 2014-03-26 | アレイ バイオファーマ、インコーポレイテッド | グルコキナーゼ活性化剤としての２−アミノピリジン類似体 |
| EP2025674A1 (de) | 2007-08-15 | 2009-02-18 | sanofi-aventis | Substituierte Tetrahydronaphthaline, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
| EA019104B1 (ru) * | 2007-09-21 | 2014-01-30 | Эррей Биофарма Инк. | Активаторы глюкокиназы |
| KR20100090250A (ko) | 2007-10-09 | 2010-08-13 | 메르크 파텐트 게엠베하 | 글루코키나제 활성체로서 유용한 피리딘 유도체 |
| CN102015637B (zh) * | 2008-02-06 | 2014-05-21 | 第一三共株式会社 | 苯基吡咯衍生物 |
| US7741327B2 (en) | 2008-04-16 | 2010-06-22 | Hoffmann-La Roche Inc. | Pyrrolidinone glucokinase activators |
| WO2011107494A1 (de) | 2010-03-03 | 2011-09-09 | Sanofi | Neue aromatische glykosidderivate, diese verbindungen enthaltende arzneimittel und deren verwendung |
| CA2800498C (en) | 2010-03-31 | 2021-11-16 | The Scripps Research Institute | Reprogramming cells |
| US8178689B2 (en) | 2010-06-17 | 2012-05-15 | Hoffman-La Roche Inc. | Tricyclic compounds |
| EP2582709B1 (de) | 2010-06-18 | 2018-01-24 | Sanofi | Azolopyridin-3-on-derivate als inhibitoren von lipasen und phospholipasen |
| US8530413B2 (en) | 2010-06-21 | 2013-09-10 | Sanofi | Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments |
| TW201221505A (en) | 2010-07-05 | 2012-06-01 | Sanofi Sa | Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament |
| TW201215387A (en) | 2010-07-05 | 2012-04-16 | Sanofi Aventis | Spirocyclically substituted 1,3-propane dioxide derivatives, processes for preparation thereof and use thereof as a medicament |
| TW201215388A (en) | 2010-07-05 | 2012-04-16 | Sanofi Sa | (2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments |
| WO2012120054A1 (de) | 2011-03-08 | 2012-09-13 | Sanofi | Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung |
| EP2766349B1 (de) | 2011-03-08 | 2016-06-01 | Sanofi | Mit carbozyklen oder heterozyklen substituierte oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung |
| EP2683704B1 (de) | 2011-03-08 | 2014-12-17 | Sanofi | Verzweigte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung |
| WO2012120056A1 (de) | 2011-03-08 | 2012-09-13 | Sanofi | Tetrasubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung |
| WO2012120055A1 (de) | 2011-03-08 | 2012-09-13 | Sanofi | Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung |
| KR20140051834A (ko) | 2011-03-09 | 2014-05-02 | 다이이찌 산쿄 가부시키가이샤 | 디피리딜아민 유도체 |
| WO2013037390A1 (en) | 2011-09-12 | 2013-03-21 | Sanofi | 6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors |
| EP2760862B1 (en) | 2011-09-27 | 2015-10-21 | Sanofi | 6-(4-hydroxy-phenyl)-3-alkyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors |
| EP2850057A4 (en) | 2012-05-18 | 2016-01-27 | Amgen Inc | PROCESS FOR THE PREPARATION OF THIADIAZOLENE |
| US20150299182A1 (en) * | 2012-11-09 | 2015-10-22 | Amgen Inc. | Crystalline forms of (1s)-1-[5-(amino)-1,2,4-thiadiazol-3-yl]ethane-1,2-diol |
| HUE038820T2 (hu) | 2013-11-13 | 2018-11-28 | Vertex Pharma | Eljárás influenzavírusok replikációjának inhibitorai elõállítására |
| EP3383848B1 (en) | 2015-12-01 | 2020-01-08 | Basf Se | Pyridine compounds as fungicides |
| BR112018010316A2 (pt) | 2015-12-01 | 2018-12-04 | Basf Se | compostos de fórmula, composição, utilização de um composto de fórmula, método para o combate de fungos fitopatogênicos e semente |
| CN108329330B (zh) * | 2017-01-20 | 2021-05-04 | 复旦大学 | 2-苄氧苯基噁唑并吡啶类化合物及其药物用途 |
| UA126679C2 (uk) | 2017-05-30 | 2023-01-11 | Басф Се | Піридинові та піразинові сполуки |
| GB201714777D0 (en) | 2017-09-14 | 2017-11-01 | Univ London Queen Mary | Agent |
| BR112020008727A2 (pt) | 2017-10-30 | 2020-10-20 | Neuropore Therapies, Inc. | fenil sulfonil fenil triazol tionas substituídas e usos destas |
| EP3846793B1 (en) | 2018-09-07 | 2024-01-24 | PIC Therapeutics, Inc. | Eif4e inhibitors and uses thereof |
| BR112022012153A2 (pt) | 2019-12-19 | 2022-08-30 | Curia Spain S A U | Processo para preparar um composto e composto |
| AR121506A1 (es) | 2020-03-03 | 2022-06-08 | Pic Therapeutics Inc | Inhibidores del eif4e y sus usos |
| US12157732B2 (en) | 2021-08-25 | 2024-12-03 | PIC Therapeutics, Inc. | eIF4E inhibitors and uses thereof |
| IL310924A (en) | 2021-08-25 | 2024-04-01 | Pic Therapeutics Inc | Eif4e inhibitors and uses thereof |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3773919A (en) | 1969-10-23 | 1973-11-20 | Du Pont | Polylactide-drug mixtures |
| NZ225999A (en) | 1987-09-10 | 1992-04-28 | Merck Sharp & Dohme | Azacyclic- or azabicyclic-substituted thiadiazole derivatives and pharmaceutical compositions |
| AU7193394A (en) | 1993-08-13 | 1995-03-14 | Zeneca Limited | Thia- and oxadiazole derivatives and their use as fungicides or insecticides |
| IL113112A (en) * | 1994-03-28 | 2000-06-01 | Nissan Chemical Ind Ltd | Pyridine substituted thiazolidinediones and pharmaceutical compositions comprising them |
| US5543523A (en) | 1994-11-15 | 1996-08-06 | Regents Of The University Of Minnesota | Method and intermediates for the synthesis of korupensamines |
| MXPA02002559A (es) | 1999-09-10 | 2002-07-30 | Merck & Co Inc | Inhibidores de tirosina cinasa. |
| US20050043545A1 (en) | 2001-11-02 | 2005-02-24 | Gianpalol Bravi | 4-(5-Membered)-heteroaryl acyl pyrrolidine derivatives as hcv inhibitors |
| WO2003062224A1 (en) | 2002-01-17 | 2003-07-31 | Eli Lilly And Company | Aza-cyclic compounds as modulators of acetylcholine receptors |
| US6846928B2 (en) | 2002-03-15 | 2005-01-25 | Vertex Pharmaceuticals Incorporated | Compositions useful as inhibitors of protein kinases |
| BRPI0407283A (pt) * | 2003-02-13 | 2006-01-31 | Banyu Pharma Co Ltd | Composto, composição farmacêutica, e, agente ativador de glucoquinase, agentes terapêuticos e/ou agentes preventivos para diabetes melito e obesidade |
| AR049418A1 (es) | 2004-02-27 | 2006-08-02 | Bayer Pharmaceuticals Corp | Derivados de heteroarilaminopirazol y composiciones farmaceuticas para el tratamiento de la diabetes. |
| AU2005223610B2 (en) * | 2004-03-23 | 2008-05-29 | Banyu Pharmaceutical Co., Ltd. | Substituted quinazoline or pyridopyrimidine derivative |
| KR20070052207A (ko) * | 2005-11-16 | 2007-05-21 | 주식회사 엘지생명과학 | 신규한 ｋｄｒ 억제제 |
| RS53981B1 (sr) | 2006-03-24 | 2015-10-30 | Array Biopharma Inc. | Analozi 2-aminopiridina kao aktivatori glukokinaze |
-
2007
- 2007-03-23 RS RS20150314A patent/RS53981B1/sr unknown
- 2007-03-23 AU AU2007235558A patent/AU2007235558B2/en not_active Ceased
- 2007-03-23 EP EP12170853.1A patent/EP2543667B1/en not_active Not-in-force
- 2007-03-23 US US12/282,600 patent/US8022223B2/en not_active Expired - Fee Related
- 2007-03-23 BR BRPI0709171-0A patent/BRPI0709171A2/pt not_active Application Discontinuation
- 2007-03-23 RU RU2008141999/04A patent/RU2457207C2/ru not_active IP Right Cessation
- 2007-03-23 ES ES07754021.9T patent/ES2536547T3/es active Active
- 2007-03-23 TW TW096110176A patent/TWI393718B/zh not_active IP Right Cessation
- 2007-03-23 PL PL07754021T patent/PL2013204T3/pl unknown
- 2007-03-23 DK DK07754021T patent/DK2013204T3/en active
- 2007-03-23 NZ NZ571997A patent/NZ571997A/en not_active IP Right Cessation
- 2007-03-23 JP JP2009501610A patent/JP5377284B2/ja not_active Expired - Fee Related
- 2007-03-23 PT PT77540219T patent/PT2013204E/pt unknown
- 2007-03-23 MY MYPI20083729A patent/MY148985A/en unknown
- 2007-03-23 WO PCT/US2007/007444 patent/WO2007117381A2/en not_active Ceased
- 2007-03-23 UA UAA200812528A patent/UA103746C2/ru unknown
- 2007-03-23 MX MX2008012168A patent/MX2008012168A/es active IP Right Grant
- 2007-03-23 KR KR1020087026141A patent/KR101440634B1/ko not_active Expired - Fee Related
- 2007-03-23 CN CN2007800155903A patent/CN101437816B/zh not_active Expired - Fee Related
- 2007-03-23 HR HRP20150347TT patent/HRP20150347T1/hr unknown
- 2007-03-23 EP EP07754021.9A patent/EP2013204B1/en active Active
- 2007-03-23 SG SG201102157-3A patent/SG170775A1/en unknown
- 2007-03-23 SI SI200731636T patent/SI2013204T1/sl unknown
- 2007-03-23 CA CA2647208A patent/CA2647208C/en not_active Expired - Fee Related
-
2008
- 2008-09-17 IL IL194160A patent/IL194160A/en not_active IP Right Cessation
- 2008-10-21 ZA ZA2008/09017A patent/ZA200809017B/en unknown
-
2011
- 2011-07-27 US US13/191,994 patent/US8354540B2/en not_active Expired - Fee Related
-
2012
- 2012-11-05 US US13/669,083 patent/US8883828B2/en not_active Expired - Fee Related
-
2013
- 2013-08-22 JP JP2013171956A patent/JP2013245220A/ja not_active Withdrawn
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