PT2013204E - Análogos de 2-aminopiridina como activadores da glucoquinase - Google Patents

Análogos de 2-aminopiridina como activadores da glucoquinase Download PDF

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Publication number
PT2013204E
PT2013204E PT77540219T PT07754021T PT2013204E PT 2013204 E PT2013204 E PT 2013204E PT 77540219 T PT77540219 T PT 77540219T PT 07754021 T PT07754021 T PT 07754021T PT 2013204 E PT2013204 E PT 2013204E
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PT
Portugal
Prior art keywords
glucokinase activators
aminopyridine
analogs
aminopyridine analogs
glucokinase
Prior art date
Application number
PT77540219T
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English (en)
Inventor
Thomas Daniel Aicher
Steven Armen Boyd
Ronald Jay Hinklin
Ajay Singh
Mark Joseph Chicarelli
Kevin Ronald Condroski
Original Assignee
Array Biopharma Inc
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Publication of PT2013204E publication Critical patent/PT2013204E/pt

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    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
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  • Diabetes (AREA)
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  • Neurology (AREA)
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  • Pain & Pain Management (AREA)
  • Ophthalmology & Optometry (AREA)
  • Immunology (AREA)
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PT77540219T 2006-03-24 2007-03-23 Análogos de 2-aminopiridina como activadores da glucoquinase PT2013204E (pt)

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US78546006P 2006-03-24 2006-03-24

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PT2013204E true PT2013204E (pt) 2015-06-09

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US (3) US8022223B2 (pt)
EP (2) EP2543667B1 (pt)
JP (2) JP5377284B2 (pt)
KR (1) KR101440634B1 (pt)
CN (1) CN101437816B (pt)
AU (1) AU2007235558B2 (pt)
BR (1) BRPI0709171A2 (pt)
CA (1) CA2647208C (pt)
DK (1) DK2013204T3 (pt)
ES (1) ES2536547T3 (pt)
HK (1) HK1128130A1 (pt)
HR (1) HRP20150347T1 (pt)
IL (1) IL194160A (pt)
MX (1) MX2008012168A (pt)
MY (1) MY148985A (pt)
NZ (1) NZ571997A (pt)
PL (1) PL2013204T3 (pt)
PT (1) PT2013204E (pt)
RS (1) RS53981B1 (pt)
RU (1) RU2457207C2 (pt)
SG (1) SG170775A1 (pt)
SI (1) SI2013204T1 (pt)
TW (1) TWI393718B (pt)
UA (1) UA103746C2 (pt)
WO (1) WO2007117381A2 (pt)
ZA (1) ZA200809017B (pt)

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RU2457207C2 (ru) 2006-03-24 2012-07-27 Эррэй Биофарма Инк. Активаторы глюкокиназы
US8431713B2 (en) * 2007-01-24 2013-04-30 Array Biopharma, Inc. 2-aminopyridine derivatives as glucokinase activators
WO2008118718A2 (en) * 2007-03-23 2008-10-02 Array Biopharma Inc. 2-aminopyridine analogs as glucokinase activators
EP2025674A1 (de) 2007-08-15 2009-02-18 sanofi-aventis Substituierte Tetrahydronaphthaline, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
EP2727910B1 (en) 2007-09-21 2016-03-16 Array Biopharma, Inc. Pyridin-2-yl-thiourea and Pyridin-2-yl-amine derivatives as intermediates for the preparation of Pyridin-2yl-amino-1,2,4-thiadiazole glucokinase activators
BRPI0818658A2 (pt) * 2007-10-09 2015-04-14 Merck Patent Ges Mit Beschränkter Haftung Derivados de piridina úteis como ativadores de glicoquinase
DK2239253T3 (da) * 2008-02-06 2013-09-23 Daiichi Sankyo Co Ltd Hidtil ukendt phenylpyrrolderivat
US7741327B2 (en) 2008-04-16 2010-06-22 Hoffmann-La Roche Inc. Pyrrolidinone glucokinase activators
WO2011107494A1 (de) 2010-03-03 2011-09-09 Sanofi Neue aromatische glykosidderivate, diese verbindungen enthaltende arzneimittel und deren verwendung
CN105176930B (zh) 2010-03-31 2021-05-04 斯克里普斯研究所 重编程细胞
US8178689B2 (en) 2010-06-17 2012-05-15 Hoffman-La Roche Inc. Tricyclic compounds
WO2011157827A1 (de) 2010-06-18 2011-12-22 Sanofi Azolopyridin-3-on-derivate als inhibitoren von lipasen und phospholipasen
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