TWI393718B - 葡萄糖激酶活化劑 - Google Patents

葡萄糖激酶活化劑 Download PDF

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Publication number
TWI393718B
TWI393718B TW096110176A TW96110176A TWI393718B TW I393718 B TWI393718 B TW I393718B TW 096110176 A TW096110176 A TW 096110176A TW 96110176 A TW96110176 A TW 96110176A TW I393718 B TWI393718 B TW I393718B
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Taiwan
Prior art keywords
pyridin
amine
ylamino
ylthio
alkyl
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TW096110176A
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English (en)
Chinese (zh)
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TW200806661A (en
Inventor
Thomas Daniel Aicher
Steven Armen Boyd
Mark Joseph Chicarelli
Kevin Ronald Condroski
Ronald Jay Hinklin
Ajay Singh
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Array Biopharma Inc
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    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
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  • Diabetes (AREA)
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  • Hematology (AREA)
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  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Obesity (AREA)
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  • Urology & Nephrology (AREA)
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  • Ophthalmology & Optometry (AREA)
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TW096110176A 2006-03-24 2007-03-23 葡萄糖激酶活化劑 TWI393718B (zh)

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TWI393718B true TWI393718B (zh) 2013-04-21

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EP (2) EP2013204B1 (enExample)
JP (2) JP5377284B2 (enExample)
KR (1) KR101440634B1 (enExample)
CN (1) CN101437816B (enExample)
AU (1) AU2007235558B2 (enExample)
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WO2008091770A1 (en) * 2007-01-24 2008-07-31 Array Biopharma Inc. 2-aminopyridine derivatives as glucokinase activators
CA2681695A1 (en) * 2007-03-23 2008-10-02 Array Biopharma Inc. 2-aminopyridine analogs as glucokinase activators
EP2025674A1 (de) 2007-08-15 2009-02-18 sanofi-aventis Substituierte Tetrahydronaphthaline, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
SI2209778T1 (sl) * 2007-09-21 2012-12-31 Array Biopharma, Inc. Piridin-2-il-amino-I, 2,4-tiadiazol derivati kot aktivatorji glukokinaze za zdravljenje sladkorne bolezni
AU2008310097B2 (en) 2007-10-09 2013-05-16 Merck Patent Gmbh Pyridine derivatives useful as glucokinase activators
BRPI0908124A2 (pt) 2008-02-06 2015-08-04 Daiichi Sankyo Co Ltd Composto, ativador de glucoquinase, composição farmacêutica, uso de um composto ou sal farmacologicamente aceitavél do mesmo, e, métodos de ativação da glucoquinase, e para tratar e/ou prevenir uma doença
US7741327B2 (en) 2008-04-16 2010-06-22 Hoffmann-La Roche Inc. Pyrrolidinone glucokinase activators
WO2011107494A1 (de) 2010-03-03 2011-09-09 Sanofi Neue aromatische glykosidderivate, diese verbindungen enthaltende arzneimittel und deren verwendung
CA2800498C (en) 2010-03-31 2021-11-16 The Scripps Research Institute Reprogramming cells
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