JP2009507110A - 相互侵入ネットワーク、およびそれに関連する方法および組成物 - Google Patents

相互侵入ネットワーク、およびそれに関連する方法および組成物 Download PDF

Info

Publication number
JP2009507110A
JP2009507110A JP2008529440A JP2008529440A JP2009507110A JP 2009507110 A JP2009507110 A JP 2009507110A JP 2008529440 A JP2008529440 A JP 2008529440A JP 2008529440 A JP2008529440 A JP 2008529440A JP 2009507110 A JP2009507110 A JP 2009507110A
Authority
JP
Japan
Prior art keywords
collagen
hydrogel
hydrogel material
ipn
polymer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2008529440A
Other languages
English (en)
Japanese (ja)
Other versions
JP2009507110A5 (https=
Inventor
メイ グリフィス
フェンフ リー
ウェングァン リュウ
メルダッド ラファト
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Ottawa
Ottawa Health Research Institute
Original Assignee
University of Ottawa
Ottawa Health Research Institute
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Ottawa, Ottawa Health Research Institute filed Critical University of Ottawa
Publication of JP2009507110A publication Critical patent/JP2009507110A/ja
Publication of JP2009507110A5 publication Critical patent/JP2009507110A5/ja
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/52—Hydrogels or hydrocolloids
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L101/00—Compositions of unspecified macromolecular compounds
    • C08L101/12—Compositions of unspecified macromolecular compounds characterised by physical features, e.g. anisotropy, viscosity or electrical conductivity
    • C08L101/14—Compositions of unspecified macromolecular compounds characterised by physical features, e.g. anisotropy, viscosity or electrical conductivity the macromolecular compounds being water soluble or water swellable, e.g. aqueous gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A61K9/0051—Ocular inserts or implants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F283/00—Macromolecular compounds obtained by polymerising monomers on to polymers provided for in subclass C08G
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F283/00—Macromolecular compounds obtained by polymerising monomers on to polymers provided for in subclass C08G
    • C08F283/06—Macromolecular compounds obtained by polymerising monomers on to polymers provided for in subclass C08G on to polyethers, polyoxymethylenes or polyacetals
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08H—DERIVATIVES OF NATURAL MACROMOLECULAR COMPOUNDS
    • C08H1/00—Macromolecular products derived from proteins
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J3/00—Processes of treating or compounding macromolecular substances
    • C08J3/24—Crosslinking, e.g. vulcanising, of macromolecules
    • C08J3/246—Intercrosslinking of at least two polymers
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L33/00—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
    • C08L33/04—Homopolymers or copolymers of esters
    • C08L33/14—Homopolymers or copolymers of esters of esters containing halogen, nitrogen, sulfur, or oxygen atoms in addition to the carboxy oxygen
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
    • C08L5/04—Alginic acid; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
    • C08L5/08—Chitin; Chondroitin sulfate; Hyaluronic acid; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L89/00—Compositions of proteins; Compositions of derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L89/00—Compositions of proteins; Compositions of derivatives thereof
    • C08L89/04—Products derived from waste materials, e.g. horn, hoof or hair
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L89/00—Compositions of proteins; Compositions of derivatives thereof
    • C08L89/04—Products derived from waste materials, e.g. horn, hoof or hair
    • C08L89/06—Products derived from waste materials, e.g. horn, hoof or hair derived from leather or skin, e.g. gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J2300/00—Characterised by the use of unspecified polymers
    • C08J2300/16—Biodegradable polymers
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L2205/00—Polymer mixtures characterised by other features
    • C08L2205/04—Polymer mixtures characterised by other features containing interpenetrating networks

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dermatology (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Dispersion Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Ophthalmology & Optometry (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Materials Engineering (AREA)
  • Inorganic Chemistry (AREA)
  • Materials For Medical Uses (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Prostheses (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
  • Graft Or Block Polymers (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Medicinal Preparation (AREA)
JP2008529440A 2005-09-09 2006-09-11 相互侵入ネットワーク、およびそれに関連する方法および組成物 Pending JP2009507110A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US71541105P 2005-09-09 2005-09-09
PCT/CA2006/001520 WO2007028258A2 (en) 2005-09-09 2006-09-11 Interpenetrating networks, and related methods and compositions

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2012242985A Division JP5661722B2 (ja) 2005-09-09 2012-11-02 眼用デバイス及びその製造方法

Publications (2)

Publication Number Publication Date
JP2009507110A true JP2009507110A (ja) 2009-02-19
JP2009507110A5 JP2009507110A5 (https=) 2009-11-05

Family

ID=37836182

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2008529440A Pending JP2009507110A (ja) 2005-09-09 2006-09-11 相互侵入ネットワーク、およびそれに関連する方法および組成物
JP2012242985A Expired - Fee Related JP5661722B2 (ja) 2005-09-09 2012-11-02 眼用デバイス及びその製造方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2012242985A Expired - Fee Related JP5661722B2 (ja) 2005-09-09 2012-11-02 眼用デバイス及びその製造方法

Country Status (9)

Country Link
US (1) US20080317818A1 (https=)
EP (2) EP1934289A4 (https=)
JP (2) JP2009507110A (https=)
KR (1) KR101382083B1 (https=)
CN (1) CN101305052B (https=)
AU (1) AU2006289625B2 (https=)
CA (1) CA2621824C (https=)
SG (2) SG165337A1 (https=)
WO (1) WO2007028258A2 (https=)

Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010037316A (ja) * 2008-08-08 2010-02-18 Kanazawa Univ 神経細胞死抑制作用をもつｖｉ型コラーゲン
JP2012514231A (ja) * 2008-12-31 2012-06-21 コリア リサーチ インスティテュート オブ ケミカル テクノロジー 湿潤性の向上したハイドロゲルコンタクトレンズ
JP2013136699A (ja) * 2011-12-28 2013-07-11 Kansai Univ キチンまたはキトサンと合成高分子との複合体およびその製造方法
JP2017500113A (ja) * 2013-12-13 2017-01-05 ユタ−イナ ディーディーエス アンド アドバンスト セラピューティクス リサーチ センター 生分解性医療用接着剤又はシーラント組成物
JP2019509138A (ja) * 2016-03-22 2019-04-04 プレジデント アンド フェローズ オブ ハーバード カレッジ 生体適合性接着剤およびその使用の方法
JP2020055916A (ja) * 2018-09-28 2020-04-09 Ｓｐｉｂｅｒ株式会社 モールド成形体、モールド成形体の製造方法、およびモールド成形体の柔軟性調整方法
KR20210010246A (ko) * 2019-07-19 2021-01-27 주식회사 엘지화학 상호 침투형 구조 비드 및 그 제조 방법
KR20210010247A (ko) * 2019-07-19 2021-01-27 주식회사 엘지화학 상호 침투형 구조 비드 및 그 제조 방법
JP2022533544A (ja) * 2019-05-07 2022-07-25 ロケット フレール 創傷治療のための新規な多糖類をベースとしたヒドロゲルスキャフォールド
JP2024531725A (ja) * 2021-09-13 2024-08-29 熹微（▲蘇▼州）生物医▲薬▼科技有限公司 ポリエチレングリコール化コラーゲン様タンパク質の製造方法及びその使用
WO2024219027A1 (ja) * 2023-04-21 2024-10-24 学校法人東京理科大学 ハイドロゲル、及びハイドロゲルを形成するための組成物
US12605480B2 (en) 2019-09-20 2026-04-21 President And Fellows Of Harvard College Tough gel-based drug delivery compositions and methods thereof

Families Citing this family (184)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6302875B1 (en) 1996-10-11 2001-10-16 Transvascular, Inc. Catheters and related devices for forming passageways between blood vessels or other anatomical structures
US20070129761A1 (en) 2002-04-08 2007-06-07 Ardian, Inc. Methods for treating heart arrhythmia
US8150519B2 (en) 2002-04-08 2012-04-03 Ardian, Inc. Methods and apparatus for bilateral renal neuromodulation
US7617005B2 (en) 2002-04-08 2009-11-10 Ardian, Inc. Methods and apparatus for thermally-induced renal neuromodulation
US20080213331A1 (en) 2002-04-08 2008-09-04 Ardian, Inc. Methods and devices for renal nerve blocking
US20070135875A1 (en) 2002-04-08 2007-06-14 Ardian, Inc. Methods and apparatus for thermally-induced renal neuromodulation
US9636174B2 (en) 2002-04-08 2017-05-02 Medtronic Ardian Luxembourg S.A.R.L. Methods for therapeutic renal neuromodulation
EP1549255A4 (en) 2002-09-13 2007-12-19 Coopervision Inc DEVICES AND METHOD FOR IMPROVING THE SEA THICKNESS
ES2564694T3 (es) 2003-09-12 2016-03-28 Vessix Vascular, Inc. Sistema de remodelación y / o ablación excéntrica seleccionable de material ateroesclerótico
US20050259221A1 (en) 2004-05-20 2005-11-24 Coopervision, Inc Corneal onlays and wavefront aberration correction to enhance vision
US8396548B2 (en) 2008-11-14 2013-03-12 Vessix Vascular, Inc. Selective drug delivery in a lumen
US9713730B2 (en) 2004-09-10 2017-07-25 Boston Scientific Scimed, Inc. Apparatus and method for treatment of in-stent restenosis
US8920414B2 (en) 2004-09-10 2014-12-30 Vessix Vascular, Inc. Tuned RF energy and electrical tissue characterization for selective treatment of target tissues
US20090088846A1 (en) 2007-04-17 2009-04-02 David Myung Hydrogel arthroplasty device
US7857447B2 (en) * 2004-10-05 2010-12-28 The Board Of Trustees Of The Leland Stanford Junior University Interpenetrating polymer network hydrogel contact lenses
US7857849B2 (en) * 2004-10-05 2010-12-28 The Board Of Trustees Of The Leland Stanford Junior Iniversity Artificial corneal implant
US7909867B2 (en) * 2004-10-05 2011-03-22 The Board Of Trustees Of The Leland Stanford Junior University Interpenetrating polymer network hydrogel corneal prosthesis
JP5219518B2 (ja) 2004-12-09 2013-06-26 ザ ファウンドリー， エルエルシー 大動脈弁修復
US8019435B2 (en) 2006-05-02 2011-09-13 Boston Scientific Scimed, Inc. Control of arterial smooth muscle tone
EP2068828A2 (en) 2006-09-29 2009-06-17 SurModics, Inc. Biodegradable ocular implants and methods for treating ocular conditions
EP2076198A4 (en) 2006-10-18 2009-12-09 Minnow Medical Inc Inducing Desired Temperatreating Effects on Body Weave
EP2076194B1 (en) 2006-10-18 2013-04-24 Vessix Vascular, Inc. System for inducing desirable temperature effects on body tissue
JP5497653B2 (ja) * 2007-11-14 2014-05-21 エムアー．イ．アー ワウンドケアー 成分の制御送達のための生体材料
FR2924615B1 (fr) 2007-12-07 2010-01-22 Vivacy Lab Hydrogel cohesif biodegradable.
WO2009091733A2 (en) * 2008-01-14 2009-07-23 Coopervision International Holding Company, Lp Polymerizable contact lens formulations and contact lenses obtained therefrom
US20120209396A1 (en) 2008-07-07 2012-08-16 David Myung Orthopedic implants having gradient polymer alloys
KR20110040969A (ko) 2008-08-05 2011-04-20 바이오미메디카, 인코포레이티드 폴리우레탄-그라프트된 하이드로겔
JP5307900B2 (ja) 2008-11-17 2013-10-02 べシックス・バスキュラー・インコーポレイテッド 組織トポグラフィの知識によらないエネルギーの選択的な蓄積
FR2938544B1 (fr) * 2008-11-20 2011-01-21 Univ Cergy Pontoise Materiaux sous forme de reseaux interpenetres de polymeres associant un gel de fibrine et un reseau de polyethylene glycol
EP2398577A2 (en) * 2009-02-19 2011-12-28 Bonner, Alex Garfield Porous interpenetrating polymer network
CA2761909A1 (en) * 2009-05-14 2010-11-18 Central Michigan University Composition and method of preparation of polysaccharide gel-based artificial, biodegradable skin scaffolds
US20120142069A1 (en) * 2009-07-08 2012-06-07 Northwestern University Interpenetrating biomaterial matrices and uses thereof
EP2481399B1 (en) * 2009-08-18 2015-11-25 Tohoku University Sustained drug delivery system
US9987225B2 (en) 2009-09-30 2018-06-05 Ottawa Hospital Research Institute Crosslinked hydrogels and related method of preparation
CN103068330B (zh) 2010-04-09 2016-06-29 Vessix血管股份有限公司 用于治疗组织的功率发生和控制装置
US9192790B2 (en) 2010-04-14 2015-11-24 Boston Scientific Scimed, Inc. Focused ultrasonic renal denervation
US8473067B2 (en) 2010-06-11 2013-06-25 Boston Scientific Scimed, Inc. Renal denervation and stimulation employing wireless vascular energy transfer arrangement
CN101891946B (zh) * 2010-07-17 2012-07-04 厦门大学 一种具有dn-l结构的增强生物水凝胶及其制备方法
US9084609B2 (en) 2010-07-30 2015-07-21 Boston Scientific Scime, Inc. Spiral balloon catheter for renal nerve ablation
US9463062B2 (en) 2010-07-30 2016-10-11 Boston Scientific Scimed, Inc. Cooled conductive balloon RF catheter for renal nerve ablation
US9358365B2 (en) 2010-07-30 2016-06-07 Boston Scientific Scimed, Inc. Precision electrode movement control for renal nerve ablation
US9408661B2 (en) 2010-07-30 2016-08-09 Patrick A. Haverkost RF electrodes on multiple flexible wires for renal nerve ablation
US9155589B2 (en) 2010-07-30 2015-10-13 Boston Scientific Scimed, Inc. Sequential activation RF electrode set for renal nerve ablation
AU2011293169A1 (en) 2010-08-27 2013-03-21 Biomimedica, Inc. Hydrophobic and hydrophilic interpenetrating polymer networks derived from hydrophobic polymers and methods of preparing the same
CN101942198B (zh) * 2010-09-03 2012-05-23 东华大学 多孔硅水凝胶互穿网络（ipn）膜的制备方法
CA2811235C (en) 2010-10-01 2020-03-10 Applied Medical Resources Corporation Portable laparoscopic trainer
US8974451B2 (en) 2010-10-25 2015-03-10 Boston Scientific Scimed, Inc. Renal nerve ablation using conductive fluid jet and RF energy
US9220558B2 (en) 2010-10-27 2015-12-29 Boston Scientific Scimed, Inc. RF renal denervation catheter with multiple independent electrodes
US9028485B2 (en) 2010-11-15 2015-05-12 Boston Scientific Scimed, Inc. Self-expanding cooling electrode for renal nerve ablation
US9668811B2 (en) 2010-11-16 2017-06-06 Boston Scientific Scimed, Inc. Minimally invasive access for renal nerve ablation
US9089350B2 (en) 2010-11-16 2015-07-28 Boston Scientific Scimed, Inc. Renal denervation catheter with RF electrode and integral contrast dye injection arrangement
US9326751B2 (en) 2010-11-17 2016-05-03 Boston Scientific Scimed, Inc. Catheter guidance of external energy for renal denervation
US9060761B2 (en) 2010-11-18 2015-06-23 Boston Scientific Scime, Inc. Catheter-focused magnetic field induced renal nerve ablation
US9023034B2 (en) 2010-11-22 2015-05-05 Boston Scientific Scimed, Inc. Renal ablation electrode with force-activatable conduction apparatus
US9192435B2 (en) 2010-11-22 2015-11-24 Boston Scientific Scimed, Inc. Renal denervation catheter with cooled RF electrode
US20120157993A1 (en) 2010-12-15 2012-06-21 Jenson Mark L Bipolar Off-Wall Electrode Device for Renal Nerve Ablation
US9220561B2 (en) 2011-01-19 2015-12-29 Boston Scientific Scimed, Inc. Guide-compatible large-electrode catheter for renal nerve ablation with reduced arterial injury
KR101240133B1 (ko) 2011-01-27 2013-03-11 서울대학교산학협력단 히알루론산과 알지네이트를 포함하는 상호관입고분자망목 구조의 세포전달용 지지체의 제조방법
US9175153B2 (en) 2011-03-08 2015-11-03 The Johns Hopkins University Cellulose hydrogel compositions and contact lenses for corneal applications
US9211256B2 (en) 2011-03-08 2015-12-15 The Johns Hopkins University Wound healing compositions comprising biocompatible cellulose hydrogel membranes and methods of use thereof
US8871016B2 (en) 2011-08-03 2014-10-28 The Johns Hopkins University Cellulose-based hydrogels and methods of making thereof
JP5759615B2 (ja) 2011-04-08 2015-08-05 コヴィディエン リミテッド パートナーシップ 腎交感神経の除神経およびイオン導入薬物送達のためのイオン導入カテーテルシステムならびに方法
CN102229732B (zh) * 2011-05-11 2013-04-03 东华大学 基于半互穿网络结构的pH刺激响应性纳米水凝胶的制备
AU2012283908B2 (en) 2011-07-20 2017-02-16 Boston Scientific Scimed, Inc. Percutaneous devices and methods to visualize, target and ablate nerves
CN103813829B (zh) 2011-07-22 2016-05-18 波士顿科学西美德公司 具有可定位于螺旋引导件中的神经调制元件的神经调制系统
WO2013040559A1 (en) * 2011-09-16 2013-03-21 Wake Forest University Health Sciences Fabrication of gelatin hydrogel sheet for the transplantation of corneal endothelium
EP3357518B1 (en) 2011-10-03 2020-12-02 Hyalex Orthopaedics, Inc. Polymeric adhesive for anchoring compliant materials to another surface
EP2765942B1 (en) 2011-10-10 2016-02-24 Boston Scientific Scimed, Inc. Medical devices including ablation electrodes
WO2013055815A1 (en) 2011-10-11 2013-04-18 Boston Scientific Scimed, Inc. Off -wall electrode device for nerve modulation
US9420955B2 (en) 2011-10-11 2016-08-23 Boston Scientific Scimed, Inc. Intravascular temperature monitoring system and method
US9364284B2 (en) 2011-10-12 2016-06-14 Boston Scientific Scimed, Inc. Method of making an off-wall spacer cage
US9079000B2 (en) 2011-10-18 2015-07-14 Boston Scientific Scimed, Inc. Integrated crossing balloon catheter
US9162046B2 (en) 2011-10-18 2015-10-20 Boston Scientific Scimed, Inc. Deflectable medical devices
EP2769375B1 (en) 2011-10-21 2017-07-19 Applied Medical Resources Corporation Simulated tissue structure for surgical training
CN108095821B (zh) 2011-11-08 2021-05-25 波士顿科学西美德公司 孔部肾神经消融
US9119600B2 (en) 2011-11-15 2015-09-01 Boston Scientific Scimed, Inc. Device and methods for renal nerve modulation monitoring
WO2013078284A1 (en) 2011-11-21 2013-05-30 Biomimedica, Inc. Systems, devices, and methods for anchoring orthopaedic implants to bone
US9119632B2 (en) 2011-11-21 2015-09-01 Boston Scientific Scimed, Inc. Deflectable renal nerve ablation catheter
AU2012358851B2 (en) 2011-12-20 2016-08-11 Applied Medical Resources Corporation Advanced surgical simulation
CN102532566B (zh) * 2011-12-21 2013-09-25 四川大学 互穿网络复合水凝胶的制备方法
US9265969B2 (en) 2011-12-21 2016-02-23 Cardiac Pacemakers, Inc. Methods for modulating cell function
JP6158830B2 (ja) 2011-12-23 2017-07-05 べシックス・バスキュラー・インコーポレイテッド 身体通路の組織又は身体通路に隣接する組織をリモデリングするためのシステム、方法及び装置
WO2013101452A1 (en) 2011-12-28 2013-07-04 Boston Scientific Scimed, Inc. Device and methods for nerve modulation using a novel ablation catheter with polymeric ablative elements
US9050106B2 (en) 2011-12-29 2015-06-09 Boston Scientific Scimed, Inc. Off-wall electrode device and methods for nerve modulation
US9387276B2 (en) 2012-01-05 2016-07-12 President And Fellows Of Harvard College Interpenetrating networks with covalent and Ionic Crosslinks
CN102688525B (zh) * 2012-05-07 2013-11-27 东南大学 一种生物大分子水凝胶及其制备方法
WO2013169927A1 (en) 2012-05-08 2013-11-14 Boston Scientific Scimed, Inc. Renal nerve modulation devices
CN102631711B (zh) * 2012-05-16 2014-03-26 金陵科技学院 一种水凝胶角膜接触镜药物载体
WO2014032016A1 (en) 2012-08-24 2014-02-27 Boston Scientific Scimed, Inc. Intravascular catheter with a balloon comprising separate microporous regions
WO2014043687A2 (en) 2012-09-17 2014-03-20 Boston Scientific Scimed, Inc. Self-positioning electrode system and method for renal nerve modulation
WO2014047411A1 (en) 2012-09-21 2014-03-27 Boston Scientific Scimed, Inc. System for nerve modulation and innocuous thermal gradient nerve block
WO2014047454A2 (en) 2012-09-21 2014-03-27 Boston Scientific Scimed, Inc. Self-cooling ultrasound ablation catheter
JP2015532450A (ja) 2012-09-26 2015-11-09 アプライド メディカル リソーシーズ コーポレイション 腹腔鏡処置のための外科訓練モデル
CA3159450A1 (en) 2012-09-27 2014-04-03 Applied Medical Resources Corporation Surgical training model for laparoscopic procedures
US10679520B2 (en) 2012-09-27 2020-06-09 Applied Medical Resources Corporation Surgical training model for laparoscopic procedures
JP6074051B2 (ja) 2012-10-10 2017-02-01 ボストン サイエンティフィック サイムド，インコーポレイテッドＢｏｓｔｏｎ Ｓｃｉｅｎｔｉｆｉｃ Ｓｃｉｍｅｄ，Ｉｎｃ． 血管内神経変調システム及び医療用デバイス
CN102895699A (zh) * 2012-11-19 2013-01-30 江南大学 一种用于皮肤创伤修复的复合水凝胶敷料的制备方法
JP6482478B2 (ja) 2013-03-01 2019-03-13 アプライド メディカル リソーシーズ コーポレイション 手術シミュレーションシステム及び方法
US9956033B2 (en) 2013-03-11 2018-05-01 Boston Scientific Scimed, Inc. Medical devices for modulating nerves
US9693821B2 (en) 2013-03-11 2017-07-04 Boston Scientific Scimed, Inc. Medical devices for modulating nerves
CN103131054B (zh) * 2013-03-12 2015-05-13 武汉大学 一种高强度水凝胶
US9808311B2 (en) 2013-03-13 2017-11-07 Boston Scientific Scimed, Inc. Deflectable medical devices
JP6220044B2 (ja) 2013-03-15 2017-10-25 ボストン サイエンティフィック サイムド，インコーポレイテッドＢｏｓｔｏｎ Ｓｃｉｅｎｔｉｆｉｃ Ｓｃｉｍｅｄ，Ｉｎｃ． 腎神経アブレーションのための医療用デバイス
US10265122B2 (en) 2013-03-15 2019-04-23 Boston Scientific Scimed, Inc. Nerve ablation devices and related methods of use
EP2967725B1 (en) 2013-03-15 2019-12-11 Boston Scientific Scimed, Inc. Control unit for detecting electrical leakage between electrode pads and system comprising such a control unit
US10336896B2 (en) * 2013-04-25 2019-07-02 The University Of Akron One-pot synthesis of highly mechanical and recoverable double-network hydrogels
CN103272268B (zh) * 2013-05-16 2015-04-22 华南理工大学 一种抗菌角膜修复材料及其制备方法
EP3011550B1 (en) 2013-06-18 2018-01-03 Applied Medical Resources Corporation Gallbladder model
EP3010437A1 (en) 2013-06-21 2016-04-27 Boston Scientific Scimed, Inc. Renal denervation balloon catheter with ride along electrode support
WO2014205399A1 (en) 2013-06-21 2014-12-24 Boston Scientific Scimed, Inc. Medical devices for renal nerve ablation having rotatable shafts
US9707036B2 (en) 2013-06-25 2017-07-18 Boston Scientific Scimed, Inc. Devices and methods for nerve modulation using localized indifferent electrodes
JP6204579B2 (ja) 2013-07-01 2017-09-27 ボストン サイエンティフィック サイムド，インコーポレイテッドＢｏｓｔｏｎ Ｓｃｉｅｎｔｉｆｉｃ Ｓｃｉｍｅｄ，Ｉｎｃ． 腎神経アブレーション用医療器具
US10413357B2 (en) 2013-07-11 2019-09-17 Boston Scientific Scimed, Inc. Medical device with stretchable electrode assemblies
WO2015006480A1 (en) 2013-07-11 2015-01-15 Boston Scientific Scimed, Inc. Devices and methods for nerve modulation
US9925001B2 (en) 2013-07-19 2018-03-27 Boston Scientific Scimed, Inc. Spiral bipolar electrode renal denervation balloon
US10342609B2 (en) 2013-07-22 2019-07-09 Boston Scientific Scimed, Inc. Medical devices for renal nerve ablation
CN105392435B (zh) 2013-07-22 2018-11-09 波士顿科学国际有限公司 具有扭绞球囊的肾神经消融导管
US10198966B2 (en) 2013-07-24 2019-02-05 Applied Medical Resources Corporation Advanced first entry model for surgical simulation
AU2014293036B2 (en) 2013-07-24 2017-12-21 Applied Medical Resources Corporation First entry model
US10722300B2 (en) 2013-08-22 2020-07-28 Boston Scientific Scimed, Inc. Flexible circuit having improved adhesion to a renal nerve modulation balloon
WO2015035047A1 (en) 2013-09-04 2015-03-12 Boston Scientific Scimed, Inc. Radio frequency (rf) balloon catheter having flushing and cooling capability
WO2015032985A1 (en) * 2013-09-09 2015-03-12 Uab Ferentis Transparent hydrogel and method of making the same from functionalized natural polymers
WO2015038947A1 (en) 2013-09-13 2015-03-19 Boston Scientific Scimed, Inc. Ablation balloon with vapor deposited cover layer
US11246654B2 (en) 2013-10-14 2022-02-15 Boston Scientific Scimed, Inc. Flexible renal nerve ablation devices and related methods of use and manufacture
EP3057488B1 (en) 2013-10-14 2018-05-16 Boston Scientific Scimed, Inc. High resolution cardiac mapping electrode array catheter
US10166314B2 (en) 2013-10-14 2019-01-01 Uab Ferentis Regenerative prostheses as alternatives to donor corneas for transplantation
US9962223B2 (en) 2013-10-15 2018-05-08 Boston Scientific Scimed, Inc. Medical device balloon
US9770606B2 (en) 2013-10-15 2017-09-26 Boston Scientific Scimed, Inc. Ultrasound ablation catheter with cooling infusion and centering basket
US10945786B2 (en) 2013-10-18 2021-03-16 Boston Scientific Scimed, Inc. Balloon catheters with flexible conducting wires and related methods of use and manufacture
US10271898B2 (en) 2013-10-25 2019-04-30 Boston Scientific Scimed, Inc. Embedded thermocouple in denervation flex circuit
EP3071236A4 (en) 2013-11-20 2017-05-24 Trustees of Boston University Injectable tissue supplement
CN103655002A (zh) * 2013-12-13 2014-03-26 无锡合众信息科技有限公司 一种水凝胶人工晶体及其制备方法
US9512279B2 (en) * 2013-12-18 2016-12-06 Universite Cegy-Pontoise Interpenetrating polymer network
EP3091922B1 (en) 2014-01-06 2018-10-17 Boston Scientific Scimed, Inc. Tear resistant flex circuit assembly
EP3424453B1 (en) 2014-02-04 2026-04-01 Boston Scientific Scimed, Inc. Alternative placement of thermal sensors on bipolar electrode
US11000679B2 (en) 2014-02-04 2021-05-11 Boston Scientific Scimed, Inc. Balloon protection and rewrapping devices and related methods of use
ES3048176T3 (en) 2014-03-26 2025-12-09 Applied Med Resources Simulated dissectible tissue
AU2015347077B2 (en) 2014-11-13 2021-08-12 Applied Medical Resources Corporation Simulated tissue models and methods
WO2016100355A1 (en) * 2014-12-15 2016-06-23 The Regents Of The University Of Colorado, A Body Corporate Biocompatible hydrogels, systems including the hydrogels, and methods of using and forming same
KR102776500B1 (ko) 2015-02-19 2025-03-06 어플라이드 메디컬 리소시스 코포레이션 시뮬레이션된 조직 구조체들 및 방법들
CA2980776A1 (en) 2015-05-14 2016-11-17 Applied Medical Resources Corporation Synthetic tissue structures for electrosurgical training and simulation
US12512017B2 (en) 2015-05-27 2025-12-30 Applied Medical Resources Corporation Surgical training model for laparoscopic procedures
KR20250165689A (ko) 2015-06-09 2025-11-26 어플라이드 메디컬 리소시스 코포레이션 자궁 절제술 모델
CA3249585A1 (en) 2015-07-16 2025-02-24 Applied Medical Resources Corporation Simulated dissectable tissue
JP6862413B2 (ja) 2015-07-22 2021-04-21 アプライド メディカル リソーシーズ コーポレイション 虫垂切除術用モデル
US11077228B2 (en) 2015-08-10 2021-08-03 Hyalex Orthopaedics, Inc. Interpenetrating polymer networks
JP6916781B2 (ja) 2015-10-02 2021-08-11 アプライド メディカル リソーシーズ コーポレイション 子宮摘出術用モデル
AU2016358076A1 (en) 2015-11-20 2018-04-12 Applied Medical Resources Corporation Simulated dissectible tissue
CN105833344B (zh) * 2016-04-26 2019-04-26 青岛慧生惠众生物科技有限公司 一种可注射水凝胶在制备眼内填充物中的应用
CN106220793B (zh) * 2016-06-03 2017-10-24 深圳市前海金卓生物技术有限公司 超压缩导电性和磁性响应凝胶机器人
WO2018005301A1 (en) 2016-06-27 2018-01-04 Applied Medical Resources Corporation Simulated abdominal wall
CN113456889B (zh) * 2016-07-27 2022-06-28 珐博进(中国)医药技术开发有限公司 生物合成角膜
EP3291208B1 (en) * 2016-08-31 2020-09-30 Ricoh Company, Ltd. Hydrogel structure, blood vessel, internal organ model, practice tool for medical procedure, and method of manufacturing the hydrogel structure
US11426492B2 (en) 2016-10-13 2022-08-30 Eosvision (Suzhou) Biomedical Technology Co., Ltd Collagen and collagen like peptide based hyrdogels, corneal implants, filler glue and uses thereof
WO2018144966A1 (en) * 2017-02-06 2018-08-09 The Board Of Trustees Of The Leland Stanford Junior University Bioconjugation methods for targeted in situ therapeutic delivery
ES3004046T3 (en) 2017-02-14 2025-03-11 Applied Med Resources Laparoscopic training system
US10847057B2 (en) 2017-02-23 2020-11-24 Applied Medical Resources Corporation Synthetic tissue structures for electrosurgical training and simulation
JP7402152B2 (ja) * 2017-07-27 2023-12-20 ユニバーシティー ヘルス ネットワーク イン・ビトロおよびイン・ビボにおける組織伝導の増強のための導電性安息香酸系ポリマー含有生体材料
CN107469139B (zh) * 2017-07-31 2021-01-22 河南工程学院 一种兼具有抗菌和消炎效果的高强度创伤敷料的制备方法
KR101944008B1 (ko) 2017-09-18 2019-01-30 (주) 제이씨바이오 히알루론산을 포함하는 투명 하이드로겔 막 및 이를 이용한 콘택트렌즈
CN108144109A (zh) * 2017-12-28 2018-06-12 浙江海创医疗器械有限公司 一种含蜂蜜的互穿网络交联结构的水凝胶敷料
WO2019132604A2 (ko) * 2017-12-29 2019-07-04 (주) 비이에프메디컬 인간 섬유연골 또는 탄성연골 재생용 조성물
US11116561B2 (en) 2018-01-24 2021-09-14 Medtronic Ardian Luxembourg S.A.R.L. Devices, agents, and associated methods for selective modulation of renal nerves
CN109021166A (zh) * 2018-07-03 2018-12-18 北京理工大学 一种简易快速制备高粘附作用力水凝胶双层膜的方法
US10869950B2 (en) 2018-07-17 2020-12-22 Hyalex Orthopaedics, Inc. Ionic polymer compositions
CN109589455B (zh) * 2018-11-07 2022-02-15 山东大学第二医院 一种热变性胶原蛋白或热变性真皮支架替代物及制备方法
CN109481730B (zh) * 2018-11-27 2021-10-26 五邑大学 海藻酸钙/聚乙二醇(二醇)二丙烯酸酯三维纤维网络凝胶及其制备方法和应用
EP3888708B1 (en) * 2018-11-30 2024-01-03 Nextbiomedical Co., Ltd. Hydrogel particles for chemoembolization comprising biodegradable polymer
CN111481735A (zh) * 2019-01-25 2020-08-04 华中科技大学同济医学院附属协和医院 一种医用抗菌护创水凝胶敷料及其制备方法
CN110448727B (zh) * 2019-09-17 2021-10-19 南通大学 一种粘性水凝胶材料、免缝合人工神经导管及其制备方法
CN110760076B (zh) * 2019-11-06 2022-04-08 大连理工大学 一种基于胶体颗粒-iPRF双网络结构的可注射、高强度复合水凝胶及其制备方法和应用
CN110743038B (zh) * 2019-11-06 2021-09-10 大连理工大学 一种双网络结构复合水凝胶及其制备方法和应用
CN112108083A (zh) * 2020-09-09 2020-12-22 江南大学 一种n-烷基乳糖胺表面活性剂小分子水凝胶及其制备方法
WO2022104457A1 (en) * 2020-11-18 2022-05-27 The University Of British Columbia Protein hydrogels and methods for their preparation
CN113134113B (zh) * 2021-04-07 2022-07-01 赛克赛斯生物科技股份有限公司 可吸收止血流体明胶的制备方法及可吸收止血流体明胶
WO2022272090A1 (en) * 2021-06-24 2022-12-29 Rvo 2.0, Inc, D/B/A Optics Medical Hydrogel composition and methods of use
WO2022272107A1 (en) * 2021-06-24 2022-12-29 Rvo 2.0, Inc, D/B/A Optics Medical Corneal inlay implant
CN114381083B (zh) * 2021-12-17 2023-03-24 浙江理工大学上虞工业技术研究院有限公司 一种角膜接触镜用抗菌抗氧化水凝胶及其制备方法
CN114716724B (zh) * 2022-03-16 2023-08-22 华南理工大学 一种基于墨鱼骨的仿生智能水凝胶及其制备方法
CN114796620B (zh) * 2022-04-24 2023-09-29 广东顺德工业设计研究院(广东顺德创新设计研究院) 一种用作医用植入材料的互穿网络水凝胶及其制备方法和应用
CN114773692B (zh) * 2022-06-20 2022-09-27 北京智枢生物科技有限公司 一种可长期控制ngf释放的活性生物凝胶及其应用
CN116392397B (zh) * 2023-04-13 2024-05-31 四川大学 一种光响应排龈材料及制备方法和应用
CN116985489B (zh) * 2023-07-18 2025-05-30 郑州大学 一种智能响应的双层水凝胶及其制备方法和应用
CN117467074B (zh) * 2023-10-23 2024-07-12 苏州健雄职业技术学院 一种基于两性离子聚合物凝胶的生物降解纳米酶的制备与应用

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6145765A (ja) * 1984-08-07 1986-03-05 宇部興産株式会社 血管補綴物及びその製造方法
JPH08504841A (ja) * 1992-07-03 1996-05-28 ミニステーロ・デル・ウニベルシタ・エ・デルラ・リシェルカ・シエンティフィカ・エ・テクノロジカ 相互貫入ポリマー網（ｉｐｎ）におけるヒアルロン酸およびその誘導体
WO2004014969A1 (en) * 2002-08-09 2004-02-19 Ottawa Health Research Institute Bio-synthetic matrix and uses thereof
WO2004101018A1 (en) * 2003-05-08 2004-11-25 Advanced Cardiovascular Systems, Inc. Stent coatings comprising hydrophilic additives

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4388428A (en) * 1981-07-20 1983-06-14 National Patent Development Corporation Biologically stabilized compositions comprising collagen as the major component with ethylenically unsaturated compounds used as contact lenses
US4452929A (en) 1983-09-09 1984-06-05 Celanese Corporation Water reducible epoxy based coating compositions
US4731078A (en) * 1985-08-21 1988-03-15 Kingston Technologies Limited Partnership Intraocular lens
US5112350A (en) * 1986-10-16 1992-05-12 Cbs Lens, A California General Partnership Method for locating on a cornea an artificial lens fabricated from a collagen-hydrogel for promoting epithelial cell growth and regeneration of the stroma
US5114627A (en) * 1986-10-16 1992-05-19 Cbs Lens Method for producing a collagen hydrogel
CA2066660C (en) * 1989-09-15 2002-07-30 Cary Reich Method for achieving epithelialization of synthetic lenses
US5112250A (en) * 1991-05-31 1992-05-12 Wang Tsan Chi T-type coaxial cable connector
US5632773A (en) * 1994-05-03 1997-05-27 Allergan, Inc. Biostable corneal implants
US5518732A (en) * 1995-02-14 1996-05-21 Chiron Vision, Inc. Bio-erodible ophthalmic shield
WO1997022371A1 (en) * 1995-12-18 1997-06-26 Collagen Corporation Crosslinked polymer compositions and methods for their use
US5746633A (en) * 1996-01-22 1998-05-05 Jeffrey; Lawrence W. Personal flotation device
US5718012A (en) * 1996-05-28 1998-02-17 Organogenesis, Inc. Method of strength enhancement of collagen constructs
CN1176272A (zh) * 1996-09-12 1998-03-18 翟光远 蓖麻油型互穿网络聚合物的制备方法
CN1102614C (zh) * 1996-12-20 2003-03-05 香港中文大学 新型高分子凝胶体及其应用
US6030634A (en) * 1996-12-20 2000-02-29 The Chinese University Of Hong Kong Polymer gel composition and uses therefor
US6224893B1 (en) * 1997-04-11 2001-05-01 Massachusetts Institute Of Technology Semi-interpenetrating or interpenetrating polymer networks for drug delivery and tissue engineering
US6113629A (en) * 1998-05-01 2000-09-05 Micrus Corporation Hydrogel for the therapeutic treatment of aneurysms
US6899889B1 (en) * 1998-11-06 2005-05-31 Neomend, Inc. Biocompatible material composition adaptable to diverse therapeutic indications
US20030020870A1 (en) * 2001-06-27 2003-01-30 Zms, Llc Biomedical molding materials from semi-solid precursors
TW574302B (en) * 2001-08-10 2004-02-01 Ind Tech Res Inst A method for producing cross-linked hyaluronic acid-protein bio-composites
US6552172B2 (en) * 2001-08-30 2003-04-22 Habto Biotech, Inc. Fibrin nanoparticles and uses thereof
WO2003089506A1 (en) * 2002-04-22 2003-10-30 Purdue Research Foundation Hydrogels having enhanced elasticity and mechanical strength properties
CN1662192A (zh) * 2002-06-18 2005-08-31 利兰·斯坦福初级大学董事会 人造角膜
US7476398B1 (en) * 2002-06-28 2009-01-13 Universite Laval Corneal implant and uses thereof
US20040147016A1 (en) * 2002-09-30 2004-07-29 Rowley Jonathan A. Programmable scaffold and methods for making and using the same
CA2430185A1 (en) * 2003-05-28 2004-11-28 Heather D. Sheardown Ophthalmic biomaterials and preparation thereof
ES2609105T3 (es) * 2004-05-20 2017-04-18 Mentor Worldwide Llc Método de enlance covalente de ácido hialurónico y quitosano
KR20070053217A (ko) * 2004-08-13 2007-05-23 오타와 헬쓰 리서치 인스티튜트 시력 향상 안과용 장치 및 이와 관련된 방법 및 조성물
US7857849B2 (en) * 2004-10-05 2010-12-28 The Board Of Trustees Of The Leland Stanford Junior Iniversity Artificial corneal implant
US20060287721A1 (en) * 2004-10-05 2006-12-21 David Myung Artificial cornea

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6145765A (ja) * 1984-08-07 1986-03-05 宇部興産株式会社 血管補綴物及びその製造方法
JPH08504841A (ja) * 1992-07-03 1996-05-28 ミニステーロ・デル・ウニベルシタ・エ・デルラ・リシェルカ・シエンティフィカ・エ・テクノロジカ 相互貫入ポリマー網（ｉｐｎ）におけるヒアルロン酸およびその誘導体
WO2004014969A1 (en) * 2002-08-09 2004-02-19 Ottawa Health Research Institute Bio-synthetic matrix and uses thereof
WO2004101018A1 (en) * 2003-05-08 2004-11-25 Advanced Cardiovascular Systems, Inc. Stent coatings comprising hydrophilic additives
JP2007515199A (ja) * 2003-05-08 2007-06-14 アドヴァンスド カーディオヴァスキュラー システムズ， インコーポレイテッド 親水性添加剤を含むステント用コーティング

Cited By (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010037316A (ja) * 2008-08-08 2010-02-18 Kanazawa Univ 神経細胞死抑制作用をもつｖｉ型コラーゲン
JP2012514231A (ja) * 2008-12-31 2012-06-21 コリア リサーチ インスティテュート オブ ケミカル テクノロジー 湿潤性の向上したハイドロゲルコンタクトレンズ
JP2013136699A (ja) * 2011-12-28 2013-07-11 Kansai Univ キチンまたはキトサンと合成高分子との複合体およびその製造方法
JP2017500113A (ja) * 2013-12-13 2017-01-05 ユタ−イナ ディーディーエス アンド アドバンスト セラピューティクス リサーチ センター 生分解性医療用接着剤又はシーラント組成物
US10105465B2 (en) 2013-12-13 2018-10-23 Utah-Inha Dds & Advanced Therapeutics Research Center Biodegradable medical adhesive or sealant composition
US12029829B2 (en) 2016-03-22 2024-07-09 President And Fellows Of Harvard College Biocompatible adhesives and methods of use thereof
JP2019509138A (ja) * 2016-03-22 2019-04-04 プレジデント アンド フェローズ オブ ハーバード カレッジ 生体適合性接着剤およびその使用の方法
JP7137213B2 (ja) 2016-03-22 2022-09-14 プレジデント アンド フェローズ オブ ハーバード カレッジ 生体適合性接着剤およびその使用の方法
JP2020055916A (ja) * 2018-09-28 2020-04-09 Ｓｐｉｂｅｒ株式会社 モールド成形体、モールド成形体の製造方法、およびモールド成形体の柔軟性調整方法
JP7543311B2 (ja) 2019-05-07 2024-09-02 ロケット フレール 創傷治療のための新規な多糖類をベースとしたヒドロゲルスキャフォールド
JP2022533544A (ja) * 2019-05-07 2022-07-25 ロケット フレール 創傷治療のための新規な多糖類をベースとしたヒドロゲルスキャフォールド
KR20210010247A (ko) * 2019-07-19 2021-01-27 주식회사 엘지화학 상호 침투형 구조 비드 및 그 제조 방법
KR20210010246A (ko) * 2019-07-19 2021-01-27 주식회사 엘지화학 상호 침투형 구조 비드 및 그 제조 방법
KR102740475B1 (ko) * 2019-07-19 2024-12-06 주식회사 엘지화학 상호 침투형 구조 비드 및 그 제조 방법
KR102786565B1 (ko) * 2019-07-19 2025-03-24 주식회사 엘지화학 상호 침투형 구조 비드 및 그 제조 방법
US12605480B2 (en) 2019-09-20 2026-04-21 President And Fellows Of Harvard College Tough gel-based drug delivery compositions and methods thereof
JP2024531725A (ja) * 2021-09-13 2024-08-29 熹微（▲蘇▼州）生物医▲薬▼科技有限公司 ポリエチレングリコール化コラーゲン様タンパク質の製造方法及びその使用
JP7787610B2 (ja) 2021-09-13 2025-12-17 熹微（▲蘇▼州）生物医▲薬▼科技有限公司 ポリエチレングリコール化コラーゲン様タンパク質の製造方法及びその使用
WO2024219027A1 (ja) * 2023-04-21 2024-10-24 学校法人東京理科大学 ハイドロゲル、及びハイドロゲルを形成するための組成物

Also Published As

Publication number Publication date
CN101305052B (zh) 2012-10-10
CA2621824A1 (en) 2007-03-15
AU2006289625A1 (en) 2007-03-15
AU2006289625B2 (en) 2013-08-29
CA2621824C (en) 2014-10-07
KR101382083B1 (ko) 2014-04-10
EP2535041A1 (en) 2012-12-19
SG10201807556TA (en) 2018-10-30
SG165337A1 (en) 2010-10-28
JP2013039425A (ja) 2013-02-28
WO2007028258A2 (en) 2007-03-15
HK1125395A1 (en) 2009-08-07
EP1934289A4 (en) 2011-07-20
US20080317818A1 (en) 2008-12-25
KR20080065973A (ko) 2008-07-15
EP1934289A2 (en) 2008-06-25
WO2007028258A3 (en) 2007-11-08
JP5661722B2 (ja) 2015-01-28
CN101305052A (zh) 2008-11-12

Similar Documents

Publication Publication Date Title
JP5661722B2 (ja) 眼用デバイス及びその製造方法
Shen et al. Dual-crosslinked regenerative hydrogel for sutureless long-term repair of corneal defect
KR101053792B1 (ko) 생체 합성 매트릭스 및 그의 용도
CN108601861B (zh) 复合胶原水凝胶材料、包含该材料的植入式眼科装置和制造该材料和该装置的方法
Wang et al. Injectable double-network hydrogel for corneal repair
US20030232746A1 (en) Cross-linked bioactive hydrogel matrices
US20120071580A1 (en) Suturable Hybrid Superporous Hydrogel Keratoprosthesis for Cornea
EP3283510B1 (en) Collagen mimetic peptide
JP2013039425A5 (https=)
Liu et al. Sutureless transplantation using a semi-interpenetrating polymer network bioadhesive for ocular surface reconstruction
US20160144069A1 (en) Suturable hybrid superporous hydrogel keratoprosthesis for cornea
Oelker et al. Ophthalmic adhesives: a materials chemistry perspective
KR102194155B1 (ko) 온도 감응성 폴리머가 접합된 홍합 접착 단백질을 포함하는 온도 감응성 생체 소재
CN110384822B (zh) 眼用粘合封闭胶及其制备方法
JP2013048643A (ja) 透明化羊膜の作製方法及び透明化羊膜
CN117085183B (zh) 一种原位固化、无缝合移植材料及其制备方法和应用
HK1125395B (en) Interpenetrating networks, and related methods and compositions
US20230355844A1 (en) Electrospun Reinforced Suturable Artificial Cornea and Uses Thereof
Pires Moedas De Almeida Barroso Development of photosensitive biopolymers for ocular tissue engineering
WO2025044735A1 (zh) 一种低溶胀脱细胞角膜及其制备方法和应用
HK1078886B (en) Bio-synthetic matrix and uses thereof

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20090910

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20090910

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20120703

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20121002

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20121017

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20130507

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20130806

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20130813

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20131105