|
US4920132A
(en)
*
|
1987-11-03 |
1990-04-24 |
Rorer Pharmaceutical Corp. |
Quinoline derivatives and use thereof as antagonists of leukotriene D4
|
|
US5324743A
(en)
*
|
1992-12-10 |
1994-06-28 |
Eli Lilly And Company |
Leukotriene B4 antagonists
|
|
GB2279659B
(en)
|
1993-07-05 |
1998-04-22 |
Merck Patent Gmbh |
Liquid crystalline material
|
|
EP0876379A1
(en)
|
1996-01-17 |
1998-11-11 |
Novo Nordisk A/S |
Fused 1,2,4-thiadiazine and fused 1,4-thiazine derivatives, their preparation and use
|
|
WO1997028149A1
(en)
|
1996-02-02 |
1997-08-07 |
Merck & Co., Inc. |
Method for raising hdl cholesterol levels
|
|
AU721452B2
(en)
|
1996-02-02 |
2000-07-06 |
Merck & Co., Inc. |
Antidiabetic agents
|
|
ATE293963T1
(de)
|
1996-02-02 |
2005-05-15 |
Merck & Co Inc |
Verfahren zur behandlung von diabetes und verwandter krankheitszustände.
|
|
JP2002515865A
(ja)
|
1996-02-02 |
2002-05-28 |
メルク エンド カンパニー インコーポレーテッド |
抗糖尿病薬
|
|
WO1997028137A1
(en)
|
1996-02-02 |
1997-08-07 |
Merck & Co., Inc. |
Heterocyclic derivatives as antidiabetic and antiobesity agents
|
|
IL128332A0
(en)
|
1996-08-30 |
2000-01-31 |
Novo Nordisk As |
GLP-1 derivatives
|
|
EP0948327B1
(en)
|
1996-12-23 |
2006-03-08 |
Merck & Co., Inc. |
Antidiabetic agents
|
|
BR9810378A
(pt)
|
1997-07-01 |
2000-08-29 |
Novo Nordisk As |
Composto,uso do mesmo, composição farmacêutica, e, processos de tratar a diabete do tipo i ou do tipo ii, de tratar a hiperglicemia, e de diminuir a glicose do sangue em um mamìfero
|
|
RU2215004C2
(ru)
|
1997-07-16 |
2003-10-27 |
Ново Нордиск А/С |
Конденсированное производное 1,2,4-тиадиазина, фармацевтическая композиция и способ получения лекарственного препарата
|
|
CA2295930C
(en)
|
1997-07-24 |
2010-12-14 |
Yamanouchi Pharmaceutical Co., Ltd. |
Pharmaceutical compositions having cholesterol-lowering effect
|
|
AU9696198A
(en)
|
1997-10-17 |
1999-05-10 |
Aventis Pharmaceuticals Products Inc. |
Therapeutic uses of quinoline derivatives
|
|
JP2003500432A
(ja)
*
|
1999-06-01 |
2003-01-07 |
ザ・ユニバーシティ・オブ・テキサス・サウスウエスタン・メディカル・センター |
ジフェニルエーテル誘導体を用いて脱毛症を処置する方法
|
|
GB9914977D0
(en)
|
1999-06-25 |
1999-08-25 |
Glaxo Group Ltd |
Chemical compounds
|
|
TWI262185B
(en)
|
1999-10-01 |
2006-09-21 |
Eisai Co Ltd |
Carboxylic acid derivatives having anti-hyperglycemia and anti-hyperlipemia action, and pharmaceutical composition containing the derivatives
|
|
WO2001025226A1
(en)
|
1999-10-05 |
2001-04-12 |
Bethesda Pharmaceuticals, Inc. |
Dithiolane derivatives
|
|
AU1303301A
(en)
|
1999-11-10 |
2001-06-06 |
Takeda Chemical Industries Ltd. |
Body weight gain inhibitors
|
|
WO2001034137A2
(en)
|
1999-11-11 |
2001-05-17 |
Eli Lilly And Company |
Oncolytic combinations for the treatment of cancer
|
|
JP2003523336A
(ja)
|
2000-02-18 |
2003-08-05 |
メルク エンド カムパニー インコーポレーテッド |
糖尿病及び脂質障害のためのアリールオキシ酢酸
|
|
IL151517A0
(en)
|
2000-03-09 |
2003-04-10 |
Aventis Pharma Gmbh |
Therapeutic uses of ppar mediators
|
|
US6448293B1
(en)
*
|
2000-03-31 |
2002-09-10 |
Pfizer Inc. |
Diphenyl ether compounds useful in therapy
|
|
JP2001354671A
(ja)
|
2000-04-14 |
2001-12-25 |
Nippon Chemiphar Co Ltd |
ペルオキシソーム増殖剤応答性受容体δの活性化剤
|
|
FR2812876B1
(fr)
*
|
2000-08-08 |
2002-09-27 |
Galderma Res & Dev |
Nouveaux composes bi-aromatiques activateurs des recepteurs de type ppar-gamma et leur utilisation dans des compositions cosmetiques ou pharmaceutiques
|
|
EP1310494B1
(en)
|
2000-08-11 |
2012-01-25 |
Nippon Chemiphar Co., Ltd. |
PPAR (delta) ACTIVATORS
|
|
US6630504B2
(en)
*
|
2000-08-31 |
2003-10-07 |
Pfizer Inc. |
Phenoxyphenylheterocyclyl derivatives as SSRIs
|
|
GB0024361D0
(en)
|
2000-10-05 |
2000-11-22 |
Glaxo Group Ltd |
Medicaments
|
|
AU2002224138A1
(en)
|
2000-12-05 |
2002-06-18 |
Nippon Chemiphar Co. Ltd. |
Peroxisome proliferator activated receptor d activators
|
|
GB0031103D0
(en)
|
2000-12-20 |
2001-01-31 |
Glaxo Group Ltd |
Chemical compounds
|
|
GB0031107D0
(en)
|
2000-12-20 |
2001-01-31 |
Glaxo Group Ltd |
Chemical compounds
|
|
GB0031109D0
(en)
|
2000-12-20 |
2001-01-31 |
Glaxo Group Ltd |
Chemical compounds
|
|
WO2002053547A1
(en)
|
2000-12-28 |
2002-07-11 |
Takeda Chemical Industries, Ltd. |
Alkanoic acid derivatives, process for their production and use thereof
|
|
WO2002070011A2
(en)
|
2001-02-02 |
2002-09-12 |
Smithkline Beecham Corporation |
Treatment of ppar mediated diseases
|
|
US7078422B2
(en)
|
2001-03-23 |
2006-07-18 |
Nippon Chemiphar Co., Ltd. |
Activator for peroxisome proliferator-activated receptor
|
|
JP4256166B2
(ja)
|
2001-03-28 |
2009-04-22 |
エーザイ・アール・アンド・ディー・マネジメント株式会社 |
カルボン酸化合物
|
|
WO2002080899A1
(fr)
|
2001-03-30 |
2002-10-17 |
Eisai Co., Ltd. |
Agent de traitement de maladie digestive
|
|
TWI311133B
(en)
|
2001-04-20 |
2009-06-21 |
Eisai R&D Man Co Ltd |
Carboxylic acid derivativeand the salt thereof
|
|
WO2002098840A1
(en)
|
2001-06-04 |
2002-12-12 |
Eisai Co., Ltd. |
Carboxylic acid derivative and medicine comprising salt or ester of the same
|
|
FR2826574B1
(fr)
|
2001-06-29 |
2005-08-26 |
Oreal |
Compositions contenant un derive d'hydroxydiphenyl ether inhibant le developpement des odeurs corporelles
|
|
RU2004105956A
(ru)
*
|
2001-07-30 |
2005-03-27 |
Ново Нордиск А/С (DK) |
Новые производные винилкарбоновых кислот и их применение в качестве антидиабетических средств и т.п.
|
|
BRPI0211844B8
(pt)
|
2001-08-10 |
2021-05-25 |
Nippon Chemiphar Co |
composto de ácido fenóxi-acético ou um de seus sais farmaceuticamente aceitáveis, e, composição farmacêutica
|
|
US7371777B2
(en)
|
2001-08-17 |
2008-05-13 |
Eisai Co., Ltd. |
Cyclic compound and PPAR agonist
|
|
BR0212512A
(pt)
*
|
2001-09-14 |
2004-10-26 |
Tularik Inc |
Composto, composição farmacêutica e métodos para tratar um distúrbio, condição ou doença, elevar os nìveis do colesterol hdl, reduzir os nìveis de triglicerìdeo, tratar diabete, diminuir a resistência à insulina ou diminuir a pressão arterial e modular a ppardelta
|
|
PT1445258E
(pt)
|
2001-10-12 |
2009-07-02 |
Nippon Chemiphar Co |
Activador para o receptor delta activado por proliferador de peroxissoma
|
|
CN1571766A
(zh)
|
2001-10-17 |
2005-01-26 |
诺沃挪第克公司 |
二羧酸衍生物、其制备和治疗应用
|
|
DE10151390A1
(de)
|
2001-10-18 |
2003-05-08 |
Bayer Ag |
Essigsäurederivate
|
|
JP2003171275A
(ja)
|
2001-12-11 |
2003-06-17 |
Sumitomo Pharmaceut Co Ltd |
ＰＰＡＲδアゴニスト
|
|
US6648293B1
(en)
*
|
2001-12-20 |
2003-11-18 |
Braeside Plastics Corporation |
Foldable display container and method for assembling the same
|
|
AU2003217274A1
(en)
|
2002-02-25 |
2003-09-09 |
Eli Lilly And Company |
Peroxisome proliferator activated receptor modulators
|
|
EP1480957A1
(en)
|
2002-03-01 |
2004-12-01 |
Smithkline Beecham Corporation |
Hppars activators
|
|
US6867224B2
(en)
|
2002-03-07 |
2005-03-15 |
Warner-Lambert Company |
Compounds that modulate PPAR activity and methods of preparation
|
|
US20030207924A1
(en)
|
2002-03-07 |
2003-11-06 |
Xue-Min Cheng |
Compounds that modulate PPAR activity and methods of preparation
|
|
US6833380B2
(en)
|
2002-03-07 |
2004-12-21 |
Warner-Lambert Company, Llc |
Compounds that modulate PPAR activity and methods of preparation
|
|
US6875780B2
(en)
|
2002-04-05 |
2005-04-05 |
Warner-Lambert Company |
Compounds that modulate PPAR activity and methods for their preparation
|
|
DE10222034A1
(de)
|
2002-05-17 |
2003-11-27 |
Bayer Ag |
Tetrahydroisochinolin-Derivate
|
|
GB0214149D0
(en)
|
2002-06-19 |
2002-07-31 |
Glaxo Group Ltd |
Chemical compounds
|
|
GB0214254D0
(en)
|
2002-06-20 |
2002-07-31 |
Glaxo Group Ltd |
Chemical compounds
|
|
DE10229777A1
(de)
|
2002-07-03 |
2004-01-29 |
Bayer Ag |
Indolin-Phenylsulfonamid-Derivate
|
|
JPWO2004007439A1
(ja)
*
|
2002-07-10 |
2005-11-10 |
住友製薬株式会社 |
ビアリール誘導体
|
|
WO2004056740A1
(en)
|
2002-12-20 |
2004-07-08 |
Novo Nordisk A/S |
Dicarboxylic acid derivatives as ppar-agonists
|
|
US7816385B2
(en)
*
|
2002-12-20 |
2010-10-19 |
High Point Pharmaceuticals, Llc |
Dimeric dicarboxylic acid derivatives, their preparation and use
|
|
US7396850B2
(en)
|
2003-01-06 |
2008-07-08 |
Eli Lilly And Company |
Pyrazole derivative as PPAR modulator
|
|
DE10300099A1
(de)
|
2003-01-07 |
2004-07-15 |
Bayer Healthcare Ag |
Indol-Phenylsulfonamid-Derivate
|
|
CA2514363A1
(en)
|
2003-02-12 |
2004-08-26 |
Transtech Pharma, Inc. |
Substituted azole derivatives as therapeutic agents
|
|
ES2297382T3
(es)
|
2003-02-14 |
2008-05-01 |
Eli Lilly And Company |
Derivados de sulfonamida como moduladores de ppar.
|
|
JPWO2004080943A1
(ja)
|
2003-03-11 |
2006-06-08 |
小野薬品工業株式会社 |
シンナミルアルコール誘導体化合物およびその化合物を有効成分として含有する薬剤
|
|
JPWO2004080947A1
(ja)
|
2003-03-13 |
2006-06-08 |
小野薬品工業株式会社 |
イミノエーテル誘導体化合物およびその化合物を有効成分として含有する薬剤
|
|
US20060258683A1
(en)
|
2003-04-07 |
2006-11-16 |
Liu Kevin |
Para-sulfonyl substituted phenyl compounds as modulators of ppars
|
|
US7244763B2
(en)
|
2003-04-17 |
2007-07-17 |
Warner Lambert Company Llc |
Compounds that modulate PPAR activity and methods of preparation
|
|
DE602004002394T2
(de)
|
2003-04-17 |
2007-09-13 |
Kalypsys, Inc., San Diego |
(3-{3-'(2,4-bis-trifluormethyl-benzyl)-(5-ethyl-pyrimidin-2-yl)-amino]-propoxy}-phenyl)-essigsäure und verwandte verbindungen als modulatoren von ppars und verfahren zur behandlung von stoffwechselstörungen
|
|
KR20060006954A
(ko)
|
2003-04-30 |
2006-01-20 |
디 인스티튜트스 포 파마슈티컬 디스커버리, 엘엘씨 |
단백질 티로신 포스파타제-１ｂ 억제제로서의 페닐 치환된카르복실산
|
|
ATE386715T1
(de)
*
|
2003-11-25 |
2008-03-15 |
Lilly Co Eli |
Modulatoren des peroxisomproliferatoraktivierten rezeptors
|
|
RU2375358C2
(ru)
|
2004-04-01 |
2009-12-10 |
Авентис Фармасьютикалз, Инк. |
1,3,4-оксадиазол-2-оны в качестве модуляторов ppar-дельта и их применение
|
|
BRPI0508180A
(pt)
|
2004-04-01 |
2007-08-07 |
Aventis Pharma Inc |
1,3,4-oxadiazol-2-onas como moduladores de ppar delta e seu uso deste
|
|
JP2007530703A
(ja)
|
2004-04-01 |
2007-11-01 |
アベンティス・ファーマスーティカルズ・インコーポレイテツド |
Ｍｓおよびその他の脱髄疾患を治療するためのペルオキシソーム増殖因子活性化受容体デルタアゴニストの使用
|
|
ES2352085T3
(es)
|
2004-05-05 |
2011-02-15 |
High Point Pharmaceuticals, Llc |
Nuevos compuestos, su preparación y uso.
|
|
CA2564365A1
(en)
|
2004-05-14 |
2005-12-01 |
Irm Llc |
Compounds and compositions as ppar modulators
|
|
WO2007101864A2
(en)
|
2006-03-09 |
2007-09-13 |
High Point Pharmaceuticals, Llc |
Compounds that modulate ppar activity, their preparation and use
|