BRPI0211844B8 - composto de ácido fenóxi-acético ou um de seus sais farmaceuticamente aceitáveis, e, composição farmacêutica - Google Patents
composto de ácido fenóxi-acético ou um de seus sais farmaceuticamente aceitáveis, e, composição farmacêuticaInfo
- Publication number
- BRPI0211844B8 BRPI0211844B8 BR0211844A BR0211844A BRPI0211844B8 BR PI0211844 B8 BRPI0211844 B8 BR PI0211844B8 BR 0211844 A BR0211844 A BR 0211844A BR 0211844 A BR0211844 A BR 0211844A BR PI0211844 B8 BRPI0211844 B8 BR PI0211844B8
- Authority
- BR
- Brazil
- Prior art keywords
- compound
- alkyl
- phenoxy
- pharmaceutically acceptable
- pharmaceutical composition
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
- C07D263/62—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems having two or more ring systems containing condensed 1,3-oxazole rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D263/32—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D277/24—Radicals substituted by oxygen atoms
Abstract
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2001243734 | 2001-08-10 | ||
PCT/JP2002/007897 WO2003016291A1 (fr) | 2001-08-10 | 2002-08-02 | Activateur du recepteur $g(d) sensible au proliferateur de peroxysome |
Publications (3)
Publication Number | Publication Date |
---|---|
BR0211844A BR0211844A (pt) | 2004-08-31 |
BRPI0211844B1 BRPI0211844B1 (pt) | 2019-08-27 |
BRPI0211844B8 true BRPI0211844B8 (pt) | 2021-05-25 |
Family
ID=19073779
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0211844A BRPI0211844B8 (pt) | 2001-08-10 | 2002-08-02 | composto de ácido fenóxi-acético ou um de seus sais farmaceuticamente aceitáveis, e, composição farmacêutica |
Country Status (16)
Country | Link |
---|---|
US (3) | US7265137B2 (pt) |
EP (1) | EP1424330B1 (pt) |
JP (3) | JP4421895B2 (pt) |
KR (1) | KR100901683B1 (pt) |
CN (1) | CN1330641C (pt) |
AT (1) | ATE526319T1 (pt) |
AU (1) | AU2002323776B2 (pt) |
BR (1) | BRPI0211844B8 (pt) |
CA (1) | CA2457054C (pt) |
CY (1) | CY1112130T1 (pt) |
DK (1) | DK1424330T3 (pt) |
ES (1) | ES2372813T3 (pt) |
IL (2) | IL160304A0 (pt) |
MX (1) | MXPA04001258A (pt) |
PT (1) | PT1424330E (pt) |
WO (1) | WO2003016291A1 (pt) |
Families Citing this family (53)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7105551B2 (en) * | 2000-12-20 | 2006-09-12 | Smithkline Beecham Corporation | Thiazole derivatives for treating PPAR related disorders |
EP1424330B1 (en) | 2001-08-10 | 2011-09-28 | Nippon Chemiphar Co., Ltd. | Activator for peroxisome proliferator-responsive receptor delta |
DE60232739D1 (de) * | 2001-10-12 | 2009-08-06 | Nippon Chemiphar Co | Aktivator des peroxisomproliferator-aktivierten rezeptors delta |
EP1637161A4 (en) * | 2003-04-22 | 2007-06-27 | Astellas Pharma Inc | MEANS FOR THE TREATMENT OF NEURODEGENERATIVE ILLNESSES OF THE BRAIN WITH PPAR [delta] AGONIST |
NZ545943A (en) | 2003-09-19 | 2009-09-25 | Janssen Pharmaceutica Nv | 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs |
US20050203151A1 (en) * | 2003-12-19 | 2005-09-15 | Kalypsys, Inc. | Novel compounds, compositions and uses thereof for treatment of metabolic disorders and related conditions |
US7554974B2 (en) * | 2004-03-09 | 2009-06-30 | Tekelec | Systems and methods of performing stateful signaling transactions in a distributed processing environment |
EP2305352A1 (en) | 2004-04-02 | 2011-04-06 | Merck Sharp & Dohme Corp. | 5-alpha-reductase inhibitors for use in the treatment of men with metabolic and anthropometric disorders |
ATE515494T1 (de) | 2004-05-05 | 2011-07-15 | High Point Pharmaceuticals Llc | Neue verbindungen, deren herstellung und verwendung |
WO2005105726A1 (en) | 2004-05-05 | 2005-11-10 | Novo Nordisk A/S | Novel compounds, their preparation and use |
WO2006041197A1 (ja) * | 2004-10-14 | 2006-04-20 | Nippon Chemiphar Co., Ltd. | ペルオキシソーム増殖剤活性化受容体δの活性化剤 |
RU2007135745A (ru) * | 2005-02-28 | 2009-04-10 | Ниппон Кемифар Ко., Лтд. (JP) | АКТИВАТОР δ- РЕЦЕПТОРА, АКТИВИРУЕМОГО ПРОЛИФЕРАТОРОМ ПЕРОКСИСОМЫ |
US20090203908A1 (en) * | 2005-05-25 | 2009-08-13 | Nippon Chemiphar Co., Ltd. | Activator for Peroxisome Proliferator-Activated Receptor |
MX2007016374A (es) | 2005-06-30 | 2008-03-05 | Novo Nordisk As | Acidos fenoxiaceticos como activadores ppar delta. |
AU2006287521A1 (en) * | 2005-09-07 | 2007-03-15 | Plexxikon, Inc. | PPARactive compounds |
JO3006B1 (ar) | 2005-09-14 | 2016-09-05 | Janssen Pharmaceutica Nv | املاح ليسين مبتكرة من مشتقات حامض 4-((فينوكسي الكيل)ثيو) فينوكسي الخليك |
CN101272784A (zh) | 2005-09-29 | 2008-09-24 | 塞诺菲-安万特股份有限公司 | 苯基-和吡啶基-1,2,4-噁二唑酮衍生物、它们的制备方法和它们作为药物的用途 |
BRPI0616465A2 (pt) * | 2005-09-29 | 2011-06-21 | Sanofi Aventis | derivados de fenil-[1,2,4]-oxadiazol-5-ona com grupo fenila, bem como seu uso, composição farmacêutica compreendo os mesmos e processo de preparação da referida composição farmacêutica |
CN103224477A (zh) | 2005-12-22 | 2013-07-31 | 高点制药有限责任公司 | 作为PPAR-δ活化剂的苯氧基乙酸 |
US7649098B2 (en) * | 2006-02-24 | 2010-01-19 | Lexicon Pharmaceuticals, Inc. | Imidazole-based compounds, compositions comprising them and methods of their use |
JP2009529512A (ja) | 2006-03-09 | 2009-08-20 | ハイ ポイント ファーマシューティカルズ,リミティド ライアビリティ カンパニー | 新規な化合物、それらの製造法、及び使用法 |
PE20080188A1 (es) * | 2006-04-18 | 2008-03-10 | Janssen Pharmaceutica Nv | Derivados del acido benzoazepin-oxi-acetico como agonistas de ppar-delta usados para aumentar hdl-c, reducir ldl-c y reducir colesterol |
AU2013202514B2 (en) * | 2006-04-18 | 2015-09-17 | Nippon Chemiphar Co., Ltd. | Activating agent for peroxisome proliferator activated receptor delta |
RU2435764C2 (ru) * | 2006-04-18 | 2011-12-10 | Ниппон Кемифар Ко., Лтд. | АГЕНТ, АКТИВИРУЮЩИЙ РЕЦЕПТОР, АКТИВИРУЕМЫЙ ПРОЛИФЕРАТОРАМИ ПЕРОКСИСОМ δ |
WO2007122970A1 (ja) * | 2006-04-20 | 2007-11-01 | Osaka University | 核内受容体に結合するリガンド |
AU2007309570B2 (en) | 2006-10-20 | 2012-07-12 | Merck Sharp & Dohme Corp. | Substituted imidazoles as bombesin receptor subtype-3 modulators |
JP2010506916A (ja) | 2006-10-20 | 2010-03-04 | メルク エンド カムパニー インコーポレーテッド | ボンベシンレセプターサブタイプ3モジュレーターとしての置換イミダゾール |
CA2667003A1 (en) | 2006-10-20 | 2008-05-02 | Merck & Co., Inc. | Substituted imidazoles as bombesin receptor subtype-3 modulators |
FR2910893A1 (fr) * | 2006-12-29 | 2008-07-04 | Genfit Sa | Derives de (phenylthiazolyl)-phenyl-propan-1-one et de (phenyloxazolyl)-phenyl-propan-1-one substitues, preparations et utilisations. |
BRPI0811612A2 (pt) * | 2007-05-21 | 2014-11-11 | Senju Pharma Co | Composições farmacêuticas que contêm agonista ppardelta |
TW200920355A (en) * | 2007-09-06 | 2009-05-16 | Lexicon Pharmaceuticals Inc | Compositions and methods for treating immunological and inflammatory diseases and disorders |
CA2708391A1 (en) * | 2007-12-13 | 2009-06-25 | Sri International | Ppar-delta ligands and methods of their use |
US8648208B2 (en) * | 2008-04-15 | 2014-02-11 | Nippon Chemiphar Co. Ltd. | Activating agent for peroxisome proliferator activated receptor |
US8410284B2 (en) | 2008-10-22 | 2013-04-02 | Merck Sharp & Dohme Corp | Cyclic benzimidazole derivatives useful as anti-diabetic agents |
CA2741672A1 (en) | 2008-10-31 | 2010-05-06 | Merck Sharp & Dohme Corp. | Novel cyclic benzimidazole derivatives useful anti-diabetic agents |
JP5357894B2 (ja) * | 2008-12-01 | 2013-12-04 | 田辺三菱製薬株式会社 | チアゾール環を含むカルボン酸誘導体およびその医薬用途 |
JP2012116753A (ja) * | 2009-03-26 | 2012-06-21 | Nippon Chemiphar Co Ltd | ペルオキシソーム増殖剤活性化受容体の活性化剤 |
AU2010282399A1 (en) | 2009-08-14 | 2012-03-01 | Cerenis Therapeutics Holding S.A. | Use of PPAR delta ligands for the treatment or prevention of inflammation or energy metabolism/production related diseases |
EP2538784B1 (en) | 2010-02-25 | 2015-09-09 | Merck Sharp & Dohme Corp. | Benzimidazole derivatives useful anti-diabetic agents |
WO2012027331A1 (en) | 2010-08-27 | 2012-03-01 | Ironwood Pharmaceuticals, Inc. | Compositions and methods for treating or preventing metabolic syndrome and related diseases and disorders |
EP2677869B1 (en) | 2011-02-25 | 2017-11-08 | Merck Sharp & Dohme Corp. | Novel cyclic azabenzimidazole derivatives useful as anti-diabetic agents |
JP2015525782A (ja) | 2012-08-02 | 2015-09-07 | メルク・シャープ・アンド・ドーム・コーポレーションMerck Sharp & Dohme Corp. | 抗糖尿病性三環式化合物 |
CN104994848A (zh) | 2013-02-22 | 2015-10-21 | 默沙东公司 | 抗糖尿病二环化合物 |
WO2014139388A1 (en) | 2013-03-14 | 2014-09-18 | Merck Sharp & Dohme Corp. | Novel indole derivatives useful as anti-diabetic agents |
EP3043789B1 (en) | 2013-09-09 | 2020-07-08 | vTv Therapeutics LLC | Use of a ppar-delta agonists for treating muscle atrophy |
WO2015051496A1 (en) | 2013-10-08 | 2015-04-16 | Merck Sharp & Dohme Corp. | Antidiabetic tricyclic compounds |
CN105237487B (zh) * | 2015-10-19 | 2017-10-10 | 安徽中医药大学 | 含川芎嗪基查尔酮芳氧烷酸类化合物、制备方法及其应用 |
JPWO2017195875A1 (ja) * | 2016-05-12 | 2019-03-22 | 日本ケミファ株式会社 | 創傷治療剤 |
WO2018106518A1 (en) | 2016-12-06 | 2018-06-14 | Merck Sharp & Dohme Corp. | Antidiabetic heterocyclic compounds |
US10968232B2 (en) | 2016-12-20 | 2021-04-06 | Merck Sharp & Dohme Corp. | Antidiabetic spirochroman compounds |
US11634387B2 (en) | 2019-09-26 | 2023-04-25 | Abionyx Pharma Sa | Compounds useful for treating liver diseases |
WO2022189856A1 (en) * | 2021-03-08 | 2022-09-15 | Abionyx Pharma Sa | Compounds useful for treating liver diseases |
WO2023147309A1 (en) | 2022-01-25 | 2023-08-03 | Reneo Pharmaceuticals, Inc. | Use of ppar-delta agonists in the treatment of disease |
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US5089514A (en) * | 1990-06-14 | 1992-02-18 | Pfizer Inc. | 3-coxazolyl [phenyl, chromanyl or benzofuranyl]-2-hydroxypropionic acid derivatives and analogs as hypoglycemic agents |
GB9027023D0 (en) | 1990-12-12 | 1991-01-30 | Wellcome Found | Anti-atherosclerotic aryl compounds |
HUT64023A (en) | 1991-03-22 | 1993-11-29 | Sandoz Ag | Process for producing aminoguanidine derivatives and pharmaceutical compositions comprising such compounds |
CA2090283A1 (en) * | 1992-02-28 | 1993-08-29 | Nobuyuki Hamanaka | Phenoxyacetic acid derivatives |
JP3722855B2 (ja) * | 1993-09-14 | 2005-11-30 | 武田薬品工業株式会社 | 2,4−オキサゾリジンジオン誘導体およびそれを含んでなる医薬 |
GB9426448D0 (en) | 1994-12-30 | 1995-03-01 | Wellcome Found | Process |
KR100436812B1 (ko) * | 1995-01-06 | 2004-08-31 | 도레이 가부시끼가이샤 | 벤젠축합헤테로환유도체및그유도체를유효성분으로함유하는의약조성물 |
CA2171702A1 (en) * | 1995-03-14 | 1996-09-15 | Takashi Sohda | Benzofuran compounds and their use |
WO1996035688A1 (fr) | 1995-05-08 | 1996-11-14 | Nippon Chemiphar Co., Ltd. | Derives de 2,4-thiazolidinedione ou d'oxazolidinedione et agent hypoglycemique |
CN1209809A (zh) | 1996-01-22 | 1999-03-03 | 藤泽药品工业株式会社 | 新化合物 |
WO1997028115A1 (en) | 1996-02-02 | 1997-08-07 | Merck & Co., Inc. | Antidiabetic agents |
US20020032330A1 (en) * | 1996-12-24 | 2002-03-14 | Yutaka Nomura | Propionic acid derivatives |
ES2320181T3 (es) * | 1997-07-24 | 2009-05-19 | Astellas Pharma Inc. | Composiciones farmaceuticas que tienen un efecto reductor del colesterol. |
US6589969B1 (en) * | 1998-10-16 | 2003-07-08 | Ono Pharmaceutical Co., Ltd. | Carboxylic acid derivatives and drugs containing the same as the active ingredient |
GB9914977D0 (en) * | 1999-06-25 | 1999-08-25 | Glaxo Group Ltd | Chemical compounds |
ES2204684T3 (es) * | 1999-08-27 | 2004-05-01 | Eli Lilly And Company | Derivados de biaril-oxa(tia)zol y su uso como modulares de ppar. |
TW200514783A (en) * | 1999-09-22 | 2005-05-01 | Bristol Myers Squibb Co | Substituted acid derivatives useful as antiodiabetic and antiobesity agents and method |
PE20011010A1 (es) | 1999-12-02 | 2001-10-18 | Glaxo Group Ltd | Oxazoles y tiazoles sustituidos como agonista del receptor activado por el proliferador de peroxisomas humano |
JP2001354671A (ja) | 2000-04-14 | 2001-12-25 | Nippon Chemiphar Co Ltd | ペルオキシソーム増殖剤応答性受容体δの活性化剤 |
WO2002014291A1 (en) * | 2000-08-11 | 2002-02-21 | Nippon Chemiphar Co.,Ltd. | PPARδ ACTIVATORS |
GB0031109D0 (en) * | 2000-12-20 | 2001-01-31 | Glaxo Group Ltd | Chemical compounds |
JP4157381B2 (ja) * | 2001-03-23 | 2008-10-01 | 日本ケミファ株式会社 | ペルオキシソーム増殖剤応答性受容体の活性化剤 |
GB0111523D0 (en) | 2001-05-11 | 2001-07-04 | Glaxo Group Ltd | Chemical compounds |
EP1424330B1 (en) | 2001-08-10 | 2011-09-28 | Nippon Chemiphar Co., Ltd. | Activator for peroxisome proliferator-responsive receptor delta |
-
2002
- 2002-08-02 EP EP02755779A patent/EP1424330B1/en not_active Expired - Lifetime
- 2002-08-02 MX MXPA04001258A patent/MXPA04001258A/es active IP Right Grant
- 2002-08-02 AT AT02755779T patent/ATE526319T1/de active
- 2002-08-02 PT PT02755779T patent/PT1424330E/pt unknown
- 2002-08-02 ES ES02755779T patent/ES2372813T3/es not_active Expired - Lifetime
- 2002-08-02 DK DK02755779.2T patent/DK1424330T3/da active
- 2002-08-02 CN CNB028201892A patent/CN1330641C/zh not_active Expired - Lifetime
- 2002-08-02 WO PCT/JP2002/007897 patent/WO2003016291A1/ja active Application Filing
- 2002-08-02 JP JP2003521216A patent/JP4421895B2/ja not_active Expired - Fee Related
- 2002-08-02 CA CA2457054A patent/CA2457054C/en not_active Expired - Lifetime
- 2002-08-02 KR KR1020047002008A patent/KR100901683B1/ko active IP Right Grant
- 2002-08-02 AU AU2002323776A patent/AU2002323776B2/en not_active Expired
- 2002-08-02 IL IL16030402A patent/IL160304A0/xx unknown
- 2002-08-02 BR BR0211844A patent/BRPI0211844B8/pt not_active IP Right Cessation
- 2002-08-02 US US10/486,783 patent/US7265137B2/en not_active Expired - Lifetime
-
2004
- 2004-02-10 IL IL160304A patent/IL160304A/en unknown
-
2007
- 2007-07-31 US US11/888,493 patent/US7652045B2/en active Active
- 2007-07-31 US US11/888,492 patent/US7648999B2/en not_active Expired - Lifetime
-
2009
- 2009-02-16 JP JP2009032919A patent/JP2009102442A/ja active Pending
- 2009-09-03 JP JP2009203393A patent/JP5097180B2/ja not_active Expired - Fee Related
-
2011
- 2011-12-02 CY CY20111101199T patent/CY1112130T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
KR20040023741A (ko) | 2004-03-18 |
DK1424330T3 (da) | 2012-01-16 |
JP2009102442A (ja) | 2009-05-14 |
WO2003016291A1 (fr) | 2003-02-27 |
CY1112130T1 (el) | 2015-11-04 |
US7648999B2 (en) | 2010-01-19 |
BR0211844A (pt) | 2004-08-31 |
JPWO2003016291A1 (ja) | 2004-12-02 |
MXPA04001258A (es) | 2005-06-06 |
US20080009631A1 (en) | 2008-01-10 |
US7265137B2 (en) | 2007-09-04 |
BRPI0211844B1 (pt) | 2019-08-27 |
JP4421895B2 (ja) | 2010-02-24 |
US20050054674A1 (en) | 2005-03-10 |
US7652045B2 (en) | 2010-01-26 |
ES2372813T3 (es) | 2012-01-26 |
CN1330641C (zh) | 2007-08-08 |
CA2457054A1 (en) | 2003-02-27 |
JP2009280622A (ja) | 2009-12-03 |
JP5097180B2 (ja) | 2012-12-12 |
EP1424330A4 (en) | 2004-10-27 |
US20080009525A1 (en) | 2008-01-10 |
AU2002323776B2 (en) | 2008-07-31 |
KR100901683B1 (ko) | 2009-06-08 |
EP1424330A1 (en) | 2004-06-02 |
CA2457054C (en) | 2011-10-11 |
IL160304A0 (en) | 2004-07-25 |
CN1568316A (zh) | 2005-01-19 |
IL160304A (en) | 2010-12-30 |
EP1424330B1 (en) | 2011-09-28 |
ATE526319T1 (de) | 2011-10-15 |
PT1424330E (pt) | 2011-12-22 |
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