BR0109573A - Composto ou uma pró-droga ou um sal farmacologicamente aceitável do mesmo, agente, composição farmacêutica, e, uso de um composto ou uma pró-droga ou um sal farmacologicamente aceitável do mesmo - Google Patents
Composto ou uma pró-droga ou um sal farmacologicamente aceitável do mesmo, agente, composição farmacêutica, e, uso de um composto ou uma pró-droga ou um sal farmacologicamente aceitável do mesmoInfo
- Publication number
- BR0109573A BR0109573A BR0109573-0A BR0109573A BR0109573A BR 0109573 A BR0109573 A BR 0109573A BR 0109573 A BR0109573 A BR 0109573A BR 0109573 A BR0109573 A BR 0109573A
- Authority
- BR
- Brazil
- Prior art keywords
- pharmacologically acceptable
- compound
- acceptable salt
- prodrug
- agent
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 5
- 150000003839 salts Chemical class 0.000 title abstract 5
- 239000000651 prodrug Substances 0.000 title abstract 3
- 229940002612 prodrug Drugs 0.000 title abstract 3
- 239000003795 chemical substances by application Substances 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 125000006273 (C1-C3) alkyl group Chemical group 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical group [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
- 230000001857 anti-mycotic effect Effects 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 230000001747 exhibiting effect Effects 0.000 abstract 1
- 125000000325 methylidene group Chemical group [H]C([H])=* 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 125000000843 phenylene group Chemical group C1(=C(C=CC=C1)*)* 0.000 abstract 1
- 229910052717 sulfur Inorganic materials 0.000 abstract 1
- 239000011593 sulfur Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Medicinal Preparation (AREA)
Abstract
"COMPOSTO OU UMA PRó-DROGA OU UM SAL FARMACOLOGICAMENTE ACEITáVEL DO MESMO, AGENTE, COMPOSIçãO FARMACêUTICA, E, USO DE UM COMPOSTO OU UMA PRó-DROGA OU UM SAL FARMACOLOGICAMENTE ACEITáVEL DO MESMO". Compostos de fórmula geral (1) ou suas pró-drogas ou seus sais farmacologicamente aceitáveis, exibindo excelente atividade antimicótica: (I) na qual Ar^ 1^ é fenila ou semelhante; Ar^ 2^ é fenileno ou semelhante; X é enxofre ou metileno; R^ 1^ é hidrogênio OU C~ 1-3~-alquila; R^ 2^ é hidrogênio ou C~ 1-3~-alquila; e R^ 3^ é C~ 6-10~-arila opcionalmente substituída ou semelhante.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2000086943 | 2000-03-27 | ||
| PCT/JP2001/002443 WO2001072743A1 (fr) | 2000-03-27 | 2001-03-27 | Composes triazoles possedant une liaison amide |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR0109573A true BR0109573A (pt) | 2003-01-28 |
Family
ID=18603035
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR0109573-0A BR0109573A (pt) | 2000-03-27 | 2001-03-27 | Composto ou uma pró-droga ou um sal farmacologicamente aceitável do mesmo, agente, composição farmacêutica, e, uso de um composto ou uma pró-droga ou um sal farmacologicamente aceitável do mesmo |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US6653330B2 (pt) |
| EP (1) | EP1284267B1 (pt) |
| KR (1) | KR20020083530A (pt) |
| CN (1) | CN1432014A (pt) |
| AT (1) | ATE284884T1 (pt) |
| AU (2) | AU2001242798B2 (pt) |
| BR (1) | BR0109573A (pt) |
| CA (1) | CA2404701A1 (pt) |
| CZ (1) | CZ20023209A3 (pt) |
| DE (1) | DE60107836D1 (pt) |
| DK (1) | DK1284267T3 (pt) |
| HU (1) | HUP0300573A2 (pt) |
| IL (1) | IL151880A0 (pt) |
| MX (1) | MXPA02009673A (pt) |
| NO (1) | NO20024615L (pt) |
| NZ (1) | NZ521603A (pt) |
| PL (1) | PL357306A1 (pt) |
| PT (1) | PT1284267E (pt) |
| RU (1) | RU2232761C2 (pt) |
| TW (1) | TW591024B (pt) |
| WO (1) | WO2001072743A1 (pt) |
| ZA (1) | ZA200207710B (pt) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2002215213A1 (en) * | 2000-11-16 | 2002-05-27 | Sankyo Company Limited | Carbamoyl-bearing triazole fungicides |
| HUP0303249A3 (en) | 2001-02-22 | 2007-03-28 | Sankyo Co | Water-soluble triazole fungicide compounds and pharmaceutical compositions containing them |
| WO2003068142A2 (en) * | 2002-02-12 | 2003-08-21 | Fdc Limited | 1,2,4-triazol-1-yl-propan-2-ol derivatives as anti-fungal agents |
| WO2004026862A1 (ja) * | 2002-09-20 | 2004-04-01 | Sankyo Company, Limited | 水溶性トリアゾール化合物 |
| CA2528493C (en) * | 2003-06-06 | 2009-01-20 | Sankyo Company Limited | Medicinal composition containing triazole compound |
| DE102006039589A1 (de) * | 2006-08-24 | 2008-03-06 | Bayer Healthcare Ag | Aminoacyl-Prodrugs II |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1151138C (zh) * | 1995-04-06 | 2004-05-26 | 三共株式会社 | 三唑抗真菌剂 |
| JP3622882B2 (ja) * | 1996-10-04 | 2005-02-23 | 三共株式会社 | トリアゾール誘導体を含有する医薬 |
| JPH10279567A (ja) | 1997-02-04 | 1998-10-20 | Sankyo Co Ltd | トリアゾール誘導体 |
| JPH1180135A (ja) | 1997-07-08 | 1999-03-26 | Sankyo Co Ltd | 抗真菌トリアゾール化合物 |
| AU7937998A (en) * | 1997-07-08 | 1999-02-08 | Sankyo Company Limited | Antifungal triazole compounds |
-
2001
- 2001-03-23 TW TW090106942A patent/TW591024B/zh not_active IP Right Cessation
- 2001-03-27 EP EP01915807A patent/EP1284267B1/en not_active Expired - Lifetime
- 2001-03-27 WO PCT/JP2001/002443 patent/WO2001072743A1/ja active IP Right Grant
- 2001-03-27 DE DE60107836T patent/DE60107836D1/de not_active Expired - Lifetime
- 2001-03-27 AT AT01915807T patent/ATE284884T1/de not_active IP Right Cessation
- 2001-03-27 HU HU0300573A patent/HUP0300573A2/hu unknown
- 2001-03-27 DK DK01915807T patent/DK1284267T3/da active
- 2001-03-27 AU AU2001242798A patent/AU2001242798B2/en not_active Ceased
- 2001-03-27 MX MXPA02009673A patent/MXPA02009673A/es not_active Application Discontinuation
- 2001-03-27 AU AU4279801A patent/AU4279801A/xx active Pending
- 2001-03-27 RU RU2002125872/04A patent/RU2232761C2/ru not_active IP Right Cessation
- 2001-03-27 BR BR0109573-0A patent/BR0109573A/pt not_active IP Right Cessation
- 2001-03-27 KR KR1020027012730A patent/KR20020083530A/ko not_active Application Discontinuation
- 2001-03-27 CA CA002404701A patent/CA2404701A1/en not_active Abandoned
- 2001-03-27 PL PL01357306A patent/PL357306A1/xx not_active Application Discontinuation
- 2001-03-27 CZ CZ20023209A patent/CZ20023209A3/cs unknown
- 2001-03-27 NZ NZ521603A patent/NZ521603A/en unknown
- 2001-03-27 CN CN01810246A patent/CN1432014A/zh active Pending
- 2001-03-27 IL IL15188001A patent/IL151880A0/xx unknown
- 2001-03-27 PT PT01915807T patent/PT1284267E/pt unknown
-
2002
- 2002-09-25 ZA ZA200207710A patent/ZA200207710B/en unknown
- 2002-09-26 NO NO20024615A patent/NO20024615L/no not_active Application Discontinuation
- 2002-09-27 US US10/259,944 patent/US6653330B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| DK1284267T3 (da) | 2005-01-24 |
| NZ521603A (en) | 2003-10-31 |
| EP1284267A1 (en) | 2003-02-19 |
| DE60107836D1 (de) | 2005-01-20 |
| US6653330B2 (en) | 2003-11-25 |
| CA2404701A1 (en) | 2002-09-26 |
| AU4279801A (en) | 2001-10-08 |
| ATE284884T1 (de) | 2005-01-15 |
| TW591024B (en) | 2004-06-11 |
| AU2001242798B2 (en) | 2004-02-26 |
| RU2232761C2 (ru) | 2004-07-20 |
| NO20024615D0 (no) | 2002-09-26 |
| PL357306A1 (en) | 2004-07-26 |
| HUP0300573A2 (hu) | 2003-08-28 |
| KR20020083530A (ko) | 2002-11-02 |
| EP1284267B1 (en) | 2004-12-15 |
| ZA200207710B (en) | 2004-01-02 |
| IL151880A0 (en) | 2003-04-10 |
| WO2001072743A1 (fr) | 2001-10-04 |
| US20030176480A1 (en) | 2003-09-18 |
| MXPA02009673A (es) | 2003-03-10 |
| CN1432014A (zh) | 2003-07-23 |
| CZ20023209A3 (cs) | 2003-01-15 |
| PT1284267E (pt) | 2005-02-28 |
| EP1284267A4 (en) | 2004-02-11 |
| RU2002125872A (ru) | 2004-01-10 |
| NO20024615L (no) | 2002-11-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B25A | Requested transfer of rights approved |
Owner name: SANKYO COMPANY, LIMITED (JP) , SANKYO LIFETECH COM Free format text: TRANSFERIDO DE: SANKYO COMPANY, LIMITED |
|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 5A, 6A E 7A ANUIDADES. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO PUBLICADO NA RPI 1963 DE 19.08.2008. |