JP2009040767A5 - - Google Patents
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- Publication number
- JP2009040767A5 JP2009040767A5 JP2008173198A JP2008173198A JP2009040767A5 JP 2009040767 A5 JP2009040767 A5 JP 2009040767A5 JP 2008173198 A JP2008173198 A JP 2008173198A JP 2008173198 A JP2008173198 A JP 2008173198A JP 2009040767 A5 JP2009040767 A5 JP 2009040767A5
- Authority
- JP
- Japan
- Prior art keywords
- compound
- formula
- pharmaceutically acceptable
- solvate
- acceptable salt
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- 150000001875 compounds Chemical class 0.000 claims 11
- 150000003839 salts Chemical class 0.000 claims 9
- 239000012453 solvate Substances 0.000 claims 9
- -1 4-methylpent-1-yl Chemical group 0.000 claims 7
- 125000000217 alkyl group Chemical group 0.000 claims 3
- 125000006552 (C3-C8) cycloalkyl group Chemical group 0.000 claims 2
- 125000004210 cyclohexylmethyl group Chemical group [H]C([H])(*)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H] 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims 2
- PNYZSYOQKIXTEL-QMMMGPOBSA-N (2s)-2-amino-3-cyclobutyl-2-methylpropanoic acid Chemical compound OC(=O)[C@](N)(C)CC1CCC1 PNYZSYOQKIXTEL-QMMMGPOBSA-N 0.000 claims 1
- ASDHRKWLZHKRQV-VIFPVBQESA-N (2s)-2-amino-3-cyclopentyl-2-methylpropanoic acid Chemical compound OC(=O)[C@](N)(C)CC1CCCC1 ASDHRKWLZHKRQV-VIFPVBQESA-N 0.000 claims 1
- ZIMXPVDWRPAZJL-JTQLQIEISA-N (2s)-2-amino-5-ethyl-2-methylheptanoic acid Chemical compound CCC(CC)CC[C@](C)(N)C(O)=O ZIMXPVDWRPAZJL-JTQLQIEISA-N 0.000 claims 1
- VHWJJTKKTVOZNB-APPZFPTMSA-N (2s,5r)-2-amino-2,5-dimethylheptanoic acid Chemical compound CC[C@@H](C)CC[C@](C)(N)C(O)=O VHWJJTKKTVOZNB-APPZFPTMSA-N 0.000 claims 1
- 125000004493 2-methylbut-1-yl group Chemical group CC(C*)CC 0.000 claims 1
- 125000004850 cyclobutylmethyl group Chemical group C1(CCC1)C* 0.000 claims 1
- 125000004851 cyclopentylmethyl group Chemical group C1(CCCC1)C* 0.000 claims 1
- 125000001153 fluoro group Chemical group F* 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 229940124597 therapeutic agent Drugs 0.000 claims 1
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US67602505P | 2005-04-28 | 2005-04-28 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008508341A Division JP4173909B1 (ja) | 2005-04-28 | 2006-04-19 | アミノ酸誘導体 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009040767A JP2009040767A (ja) | 2009-02-26 |
| JP2009040767A5 true JP2009040767A5 (https=) | 2009-05-28 |
Family
ID=36677128
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008508341A Expired - Fee Related JP4173909B1 (ja) | 2005-04-28 | 2006-04-19 | アミノ酸誘導体 |
| JP2008173198A Ceased JP2009040767A (ja) | 2005-04-28 | 2008-07-02 | アミノ酸誘導体 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008508341A Expired - Fee Related JP4173909B1 (ja) | 2005-04-28 | 2006-04-19 | アミノ酸誘導体 |
Country Status (26)
| Country | Link |
|---|---|
| US (1) | US7612226B2 (https=) |
| EP (1) | EP1879567A1 (https=) |
| JP (2) | JP4173909B1 (https=) |
| KR (1) | KR100925900B1 (https=) |
| CN (1) | CN101166524B (https=) |
| AP (1) | AP2007004161A0 (https=) |
| AR (1) | AR054441A1 (https=) |
| AU (1) | AU2006238933B2 (https=) |
| BR (1) | BRPI0609879A2 (https=) |
| CA (1) | CA2606353C (https=) |
| CR (1) | CR9472A (https=) |
| DO (1) | DOP2006000095A (https=) |
| EA (1) | EA200701852A1 (https=) |
| GT (1) | GT200600178A (https=) |
| IL (1) | IL185790A0 (https=) |
| MA (1) | MA29408B1 (https=) |
| MX (1) | MX2007010978A (https=) |
| NL (1) | NL1031705C2 (https=) |
| NO (1) | NO20076000L (https=) |
| PE (1) | PE20061435A1 (https=) |
| SV (1) | SV2008002512A (https=) |
| TN (1) | TNSN07400A1 (https=) |
| TW (1) | TW200719889A (https=) |
| UY (1) | UY29498A1 (https=) |
| WO (1) | WO2006114707A1 (https=) |
| ZA (1) | ZA200707678B (https=) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL126999A (en) | 1996-07-24 | 2002-03-10 | Warner Lambert Co | Pharmaceutical preparations containing isobutylgaba and its history for use in the treatment of pain |
| JP4173909B1 (ja) * | 2005-04-28 | 2008-10-29 | ファイザー・リミテッド | アミノ酸誘導体 |
| WO2007057767A2 (en) * | 2005-11-17 | 2007-05-24 | Pfizer Limited | Amino acid derivatives |
| WO2008031221A1 (en) * | 2006-09-12 | 2008-03-20 | Cephalin Pharmaceuticals Inc. | Isovaline for treatment of pain |
| CN101195583B (zh) * | 2006-12-04 | 2012-07-04 | 四川抗菌素工业研究所有限公司 | 一种光学纯米那普仑及其盐的制备方法 |
| CA3003213C (en) * | 2008-09-09 | 2021-07-20 | F. Hoffmann-La Roche Ag | Polymorphs of acyl sulfonamides |
| JP2012176902A (ja) * | 2011-02-25 | 2012-09-13 | Tosoh F-Tech Inc | 新規な光学活性含フッ素化合物、その製造方法及びそれを用いた光学活性３，３，３−トリフルオロアラニンの製造方法 |
| AT514349B1 (de) * | 2013-06-12 | 2018-05-15 | Red Bull Gmbh | Alpha-alkylierte Aminosäuren (AAAAs) |
Family Cites Families (60)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB504209A (en) | 1937-12-14 | 1939-04-21 | Pirelli General Cable Works | Improvements in or relating to electric cables |
| BR6239521D0 (pt) * | 1961-08-09 | 1973-06-14 | Merck & Co Inc | Processo de preparacao de novos amino acidos |
| FR2586562B1 (fr) | 1985-09-02 | 1989-03-10 | Inst Nat Sante Rech Med | Composition pharmaceutique contenant de l'a-methylhistamine |
| DE3811256A1 (de) | 1988-04-02 | 1989-10-19 | Hoechst Ag | (alpha)-trifluormethylaminosaeure-derivate, verfahren zur herstellung von (alpha)-trifluormethylaminosaeure-derivaten und ihre verwendung als arzneimittel |
| EP0484437A4 (en) | 1989-07-27 | 1994-06-01 | Searle & Co | Renal-selective prodrugs for the treatment of hypertension |
| FR2681067B1 (fr) * | 1991-09-10 | 1993-12-17 | Elf Sanofi | Derives heterocycliques n-substitues, leur preparation, les compositions pharmaceutiques en contenant. |
| JPH042899A (ja) | 1990-04-16 | 1992-01-07 | Arakawa Chem Ind Co Ltd | 紙用サイズ剤および該サイズ剤を用いる紙サイジング方法 |
| FR2661909B1 (fr) | 1990-05-09 | 1997-08-14 | Inst Nat Sante Rech Med | Nouveaux composes agonistes du recepteur h3 de l'histamine a usage therapeutique, compositions pharmaceutiques agissant comme agonistes dudit recepteur et procede de preparation. |
| JPH051002A (ja) | 1991-02-15 | 1993-01-08 | Nikko Kyodo Co Ltd | α−アミノ酸の製造方法 |
| CA2068038A1 (en) | 1991-05-08 | 1992-11-09 | Christopher Yee | Enzymatic resolution of .alpha.-tertiary carboxylic acid esters |
| US5993775A (en) | 1991-11-27 | 1999-11-30 | Diatide, Inc. | Radioactively labeled peptides comprising a single thiol moiety |
| GB9200210D0 (en) | 1992-01-07 | 1992-02-26 | British Bio Technology | Compounds |
| AU674553B2 (en) | 1992-10-14 | 1997-01-02 | Merck & Co., Inc. | Fibrinogen receptor antagonists |
| US5362747A (en) | 1992-11-25 | 1994-11-08 | Abbott Laboratories | 2-nitroaryl and 2-cyanoaryl compounds as regulators of nitric oxide synthase |
| GB9325360D0 (en) | 1993-12-10 | 1994-02-16 | Univ Bristol | Organic compounds |
| GB9325368D0 (en) | 1993-12-10 | 1994-02-16 | Univ Bristol | Organic compounds |
| IS4261A (is) | 1994-02-21 | 1995-08-22 | Astra Aktiebolag | Nýir peptíð-ópíóíðar til meðhöndlunar á verkjum og notkun þeirra |
| DE19533617A1 (de) | 1995-09-11 | 1997-03-13 | Degussa | Neues Verfahren zur Herstellung von optisch aktiven alpha-Aminosäuren und alpha-Aminosäure-Derivaten |
| DE69624081T2 (de) | 1995-12-20 | 2003-06-12 | Agouron Pharmaceuticals, Inc. | Matrix-metalloprotease Inhibitoren |
| WO1998014208A1 (en) | 1996-09-30 | 1998-04-09 | President And Fellows Of Harvard College | Reactive ligands and covalent ligand-protein complexes |
| US5962523A (en) | 1996-10-25 | 1999-10-05 | Discovery Laboratories, Inc. | Methods of using butyric acid derivatives to protect against hair loss |
| JPH10333511A (ja) | 1997-05-30 | 1998-12-18 | Ricoh Co Ltd | 画像除去促進液、該画像除去促進液を用いた被記録材の再生方法及び再生装置 |
| JP4205191B2 (ja) | 1997-12-26 | 2009-01-07 | ダイセル化学工業株式会社 | α−アミノニトリル誘導体及びα−アミノ酸の製造方法 |
| JP4522580B2 (ja) | 1998-03-11 | 2010-08-11 | 株式会社創研 | 皮膚健全化剤 |
| WO1999054280A1 (en) * | 1998-04-17 | 1999-10-28 | Kenneth Curry | Cubane derivatives as metabotropic glutamate receptor antagonists and process for their preparation |
| PT1140945E (pt) | 1998-12-18 | 2003-10-31 | Novo Nordisk As | Derivados 1 2 4 tiadiazina fundidos a sua preparacao e a sua utilizacao |
| JP2002533318A (ja) | 1998-12-22 | 2002-10-08 | ニューロサーチ、アクティーゼルスカブ | イオンチャネル調節剤 |
| FR2788271B1 (fr) | 1999-01-07 | 2001-02-09 | Rhone Poulenc Agrochimie | Nouveau procede de preparation d'aminoacides chiraux |
| JP2002535302A (ja) | 1999-01-22 | 2002-10-22 | ファーマコア，インコーポレイテッド | 化学式１の化合物およびその誘導体の合成方法 |
| KR100440643B1 (ko) | 1999-01-28 | 2004-07-21 | 쥬가이 세이야쿠 가부시키가이샤 | 치환 페네틸아민 유도체 |
| FR2791982B1 (fr) | 1999-04-06 | 2002-12-27 | Inst Nat Sante Rech Med | Inhibiteurs de lta4 hydrolase et leurs applications therapeutiques. |
| WO2001009117A1 (en) | 1999-07-29 | 2001-02-08 | Allellix Neuroscience Inc. | Tricyclic compounds as glycine transport inhibitors |
| FR2796943A1 (fr) | 1999-07-30 | 2001-02-02 | Aventis Pharma Sa | Derives de benzoxazinnes, leur procede de preparation et leur utilisation en therapeutique |
| CA2384080C (en) | 1999-09-07 | 2012-03-20 | Kabushiki Kaisha Soken | Skin conditioner |
| JP4728548B2 (ja) | 1999-09-07 | 2011-07-20 | 三菱レイヨン株式会社 | 光学活性アミノアルコールの製造方法 |
| JP2001081013A (ja) | 1999-09-10 | 2001-03-27 | Soken Kk | 毛髪健全化剤 |
| US7300775B2 (en) | 1999-12-29 | 2007-11-27 | Verenium Corporation | Methods for producing α-substituted carboxylic acids using nitrilases and strecker reagents |
| US6656958B2 (en) | 2000-02-02 | 2003-12-02 | Abbott Laboratories | Substituted pyridine compounds useful for controlling chemical synaptic transmission |
| DE10121028A1 (de) | 2000-05-05 | 2002-01-31 | Basf Ag | Verfahren zur Herstellung von Aldehyden |
| DE10121026A1 (de) | 2000-05-05 | 2002-02-07 | Basf Ag | Verfahren zur Herstellung von Aldehyden |
| US6949658B2 (en) | 2000-05-18 | 2005-09-27 | Mitsubishi Rayon Co., Ltd. | Process for producing optically active α-amino acid and optically active α-amino acid amide |
| WO2003011799A1 (en) | 2000-07-31 | 2003-02-13 | Brandeis University | Kinetic resolutions of chirat 3- and 3-substituted carboxylic acids |
| DE10048715A1 (de) | 2000-09-30 | 2004-05-19 | Grünenthal GmbH | Verwendung von Aminosäure zur Behandlung von Schmerz |
| AUPR406901A0 (en) | 2001-03-29 | 2001-04-26 | La Trobe University | Insecticide and method of controlling insects |
| JP4715058B2 (ja) | 2001-08-02 | 2011-07-06 | Ｊｓｒ株式会社 | 感放射性樹脂組成物 |
| JP2003221328A (ja) | 2002-01-29 | 2003-08-05 | Soken Kk | 皮膚健全化剤 |
| US7038073B2 (en) | 2002-05-15 | 2006-05-02 | Genzyme Corporation | Synthesis of 2-alkyl amino acids |
| WO2004013112A1 (en) | 2002-08-01 | 2004-02-12 | Basf Aktiengesellschaft | Pesticidal fluoroalkene derivatives |
| WO2004024709A2 (en) * | 2002-09-13 | 2004-03-25 | Prescient Neuropharma Inc. | Xanthenyl cubane analogs with activity at the metabotropic glutamate receptors |
| AU2003289242A1 (en) | 2003-01-10 | 2004-08-10 | Kaneka Corporation | PROCESS FOR PRODUCING OPTICALLY ACTIVE Alpha-METHYLCYSTEINE DERIVATIVE |
| JP2005060311A (ja) * | 2003-08-13 | 2005-03-10 | Mochida Pharmaceut Co Ltd | Ｎ−（ベンゾイル）アミノ酸誘導体を有効成分とするニューロパシー性疼痛治療剤 |
| GB0322140D0 (en) * | 2003-09-22 | 2003-10-22 | Pfizer Ltd | Combinations |
| WO2005044780A1 (ja) | 2003-11-10 | 2005-05-19 | Kyorin Pharmaceutical Co., Ltd. | アミノカルボン酸誘導体とその付加塩及びｓ１ｐ受容体調節剤 |
| CA2554735A1 (en) * | 2004-01-30 | 2005-08-11 | Peplin Biolipids Pty Ltd | Therapeutic and carrier molecules |
| GB0405289D0 (en) | 2004-03-09 | 2004-04-21 | Novartis Ag | Organic compounds |
| EP1855686A1 (en) | 2005-03-01 | 2007-11-21 | Pfizer Limited | Use of pde7 inhibitors for the treatment of neuropathic pain |
| TW200642687A (en) * | 2005-03-01 | 2006-12-16 | Pfizer Ltd | Combinations comprising α-2-δ ligands |
| JP4521463B2 (ja) * | 2005-03-17 | 2010-08-11 | ファイザー株式会社 | 疼痛の治療に有用なｎ−（ｎ−スルホニルアミノメチル）シクロプロパンカルボキサミド誘導体 |
| JP4173909B1 (ja) * | 2005-04-28 | 2008-10-29 | ファイザー・リミテッド | アミノ酸誘導体 |
| BRPI0619126A2 (pt) * | 2005-12-02 | 2011-09-13 | Pfizer Ltd | derivados espirocìclicos, composição farmacêutica e usos dos mesmos |
-
2006
- 2006-04-19 JP JP2008508341A patent/JP4173909B1/ja not_active Expired - Fee Related
- 2006-04-19 KR KR1020077024860A patent/KR100925900B1/ko not_active Expired - Fee Related
- 2006-04-19 MX MX2007010978A patent/MX2007010978A/es active IP Right Grant
- 2006-04-19 BR BRPI0609879-7A patent/BRPI0609879A2/pt not_active Application Discontinuation
- 2006-04-19 AP AP2007004161A patent/AP2007004161A0/xx unknown
- 2006-04-19 EP EP06727559A patent/EP1879567A1/en not_active Withdrawn
- 2006-04-19 CA CA2606353A patent/CA2606353C/en not_active Expired - Fee Related
- 2006-04-19 CN CN2006800141982A patent/CN101166524B/zh not_active Expired - Fee Related
- 2006-04-19 EA EA200701852A patent/EA200701852A1/ru unknown
- 2006-04-19 WO PCT/IB2006/001086 patent/WO2006114707A1/en not_active Ceased
- 2006-04-19 AU AU2006238933A patent/AU2006238933B2/en not_active Ceased
- 2006-04-25 PE PE2006000431A patent/PE20061435A1/es not_active Application Discontinuation
- 2006-04-26 UY UY29498A patent/UY29498A1/es not_active Application Discontinuation
- 2006-04-26 AR ARP060101665A patent/AR054441A1/es not_active Application Discontinuation
- 2006-04-26 DO DO2006000095A patent/DOP2006000095A/es unknown
- 2006-04-27 NL NL1031705A patent/NL1031705C2/nl not_active IP Right Cessation
- 2006-04-27 GT GT200600178A patent/GT200600178A/es unknown
- 2006-04-27 TW TW095115092A patent/TW200719889A/zh unknown
- 2006-04-28 SV SV2006002512A patent/SV2008002512A/es not_active Application Discontinuation
- 2006-04-28 US US11/414,422 patent/US7612226B2/en not_active Expired - Fee Related
-
2007
- 2007-09-06 IL IL185790A patent/IL185790A0/en unknown
- 2007-09-06 ZA ZA200707678A patent/ZA200707678B/xx unknown
- 2007-10-25 CR CR9472A patent/CR9472A/es unknown
- 2007-10-26 TN TNP2007000400A patent/TNSN07400A1/fr unknown
- 2007-10-26 MA MA30323A patent/MA29408B1/fr unknown
- 2007-11-21 NO NO20076000A patent/NO20076000L/no not_active Application Discontinuation
-
2008
- 2008-07-02 JP JP2008173198A patent/JP2009040767A/ja not_active Ceased
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