EA200701852A1 - Производные аминокислот - Google Patents
Производные аминокислотInfo
- Publication number
- EA200701852A1 EA200701852A1 EA200701852A EA200701852A EA200701852A1 EA 200701852 A1 EA200701852 A1 EA 200701852A1 EA 200701852 A EA200701852 A EA 200701852A EA 200701852 A EA200701852 A EA 200701852A EA 200701852 A1 EA200701852 A1 EA 200701852A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- derivatives
- amino acids
- formula
- relates
- compound
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid, pantothenic acid
- A61K31/198—Alpha-aminoacids, e.g. alanine, edetic acids [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/325—Carbamic acids; Thiocarbamic acids; Anhydrides or salts thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/401—Proline; Derivatives thereof, e.g. captopril
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
- A61K31/405—Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4172—Imidazole-alkanecarboxylic acids, e.g. histidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
- A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C229/06—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton
- C07C229/08—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to hydrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/28—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and containing rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/04—Systems containing only non-condensed rings with a four-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
- C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
Abstract
Настоящее изобретение относится к способу лечения боли с использованием соединения формулы (I), где R, R, Rи Rтакие, как определено в описании изобретения. Данное изобретение также относится к некоторым новым производным формулы (I).
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US67602505P | 2005-04-28 | 2005-04-28 | |
PCT/IB2006/001086 WO2006114707A1 (en) | 2005-04-28 | 2006-04-19 | Amino acid derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
EA200701852A1 true EA200701852A1 (ru) | 2008-04-28 |
Family
ID=36677128
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EA200701852A EA200701852A1 (ru) | 2005-04-28 | 2006-04-19 | Производные аминокислот |
Country Status (27)
Country | Link |
---|---|
US (1) | US7612226B2 (ru) |
EP (1) | EP1879567A1 (ru) |
JP (2) | JP4173909B1 (ru) |
KR (1) | KR100925900B1 (ru) |
CN (1) | CN101166524B (ru) |
AP (1) | AP2007004161A0 (ru) |
AR (1) | AR054441A1 (ru) |
AU (1) | AU2006238933B2 (ru) |
BR (1) | BRPI0609879A2 (ru) |
CA (1) | CA2606353C (ru) |
CR (1) | CR9472A (ru) |
DO (1) | DOP2006000095A (ru) |
EA (1) | EA200701852A1 (ru) |
GT (1) | GT200600178A (ru) |
HK (1) | HK1116417A1 (ru) |
IL (1) | IL185790A0 (ru) |
MA (1) | MA29408B1 (ru) |
MX (1) | MX2007010978A (ru) |
NL (1) | NL1031705C2 (ru) |
NO (1) | NO20076000L (ru) |
PE (1) | PE20061435A1 (ru) |
SV (1) | SV2008002512A (ru) |
TN (1) | TNSN07400A1 (ru) |
TW (1) | TW200719889A (ru) |
UY (1) | UY29498A1 (ru) |
WO (1) | WO2006114707A1 (ru) |
ZA (1) | ZA200707678B (ru) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SI0934061T1 (en) | 1996-07-24 | 2003-10-31 | Warner-Lambert Company Llc | Isobutylgaba and its derivatives for the treatment of pain |
AP2007004161A0 (en) * | 2005-04-28 | 2007-10-31 | Pfizer Ltd | Amino acid derivatives |
EP1951655A2 (en) * | 2005-11-17 | 2008-08-06 | Pfizer Limited | Amino acid derivatives |
CA2664251A1 (en) * | 2006-09-12 | 2008-03-20 | Cephalin Pharmaceuticals Inc. | Isovaline for treatment of pain |
CN101195583B (zh) * | 2006-12-04 | 2012-07-04 | 四川抗菌素工业研究所有限公司 | 一种光学纯米那普仑及其盐的制备方法 |
BR122021020475B1 (pt) * | 2008-09-09 | 2022-06-07 | F. Hoffmann-La Roche Ag | Polimorfos de acil sulfonamidas, seu uso, seu processo de preparação e composição farmacêutica que os compreende |
JP2012176902A (ja) * | 2011-02-25 | 2012-09-13 | Tosoh F-Tech Inc | 新規な光学活性含フッ素化合物、その製造方法及びそれを用いた光学活性3,3,3−トリフルオロアラニンの製造方法 |
AT514349B1 (de) * | 2013-06-12 | 2018-05-15 | Red Bull Gmbh | Alpha-alkylierte Aminosäuren (AAAAs) |
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-
2006
- 2006-04-19 AP AP2007004161A patent/AP2007004161A0/xx unknown
- 2006-04-19 WO PCT/IB2006/001086 patent/WO2006114707A1/en active Application Filing
- 2006-04-19 CA CA2606353A patent/CA2606353C/en not_active Expired - Fee Related
- 2006-04-19 KR KR1020077024860A patent/KR100925900B1/ko not_active IP Right Cessation
- 2006-04-19 CN CN2006800141982A patent/CN101166524B/zh not_active Expired - Fee Related
- 2006-04-19 JP JP2008508341A patent/JP4173909B1/ja not_active Expired - Fee Related
- 2006-04-19 BR BRPI0609879-7A patent/BRPI0609879A2/pt not_active Application Discontinuation
- 2006-04-19 EP EP06727559A patent/EP1879567A1/en not_active Withdrawn
- 2006-04-19 AU AU2006238933A patent/AU2006238933B2/en not_active Ceased
- 2006-04-19 MX MX2007010978A patent/MX2007010978A/es active IP Right Grant
- 2006-04-19 EA EA200701852A patent/EA200701852A1/ru unknown
- 2006-04-25 PE PE2006000431A patent/PE20061435A1/es not_active Application Discontinuation
- 2006-04-26 AR ARP060101665A patent/AR054441A1/es not_active Application Discontinuation
- 2006-04-26 DO DO2006000095A patent/DOP2006000095A/es unknown
- 2006-04-26 UY UY29498A patent/UY29498A1/es not_active Application Discontinuation
- 2006-04-27 TW TW095115092A patent/TW200719889A/zh unknown
- 2006-04-27 NL NL1031705A patent/NL1031705C2/nl not_active IP Right Cessation
- 2006-04-27 GT GT200600178A patent/GT200600178A/es unknown
- 2006-04-28 SV SV2006002512A patent/SV2008002512A/es not_active Application Discontinuation
- 2006-04-28 US US11/414,422 patent/US7612226B2/en not_active Expired - Fee Related
-
2007
- 2007-09-06 IL IL185790A patent/IL185790A0/en unknown
- 2007-09-06 ZA ZA200707678A patent/ZA200707678B/xx unknown
- 2007-10-25 CR CR9472A patent/CR9472A/es unknown
- 2007-10-26 MA MA30323A patent/MA29408B1/fr unknown
- 2007-10-26 TN TNP2007000400A patent/TNSN07400A1/fr unknown
- 2007-11-21 NO NO20076000A patent/NO20076000L/no not_active Application Discontinuation
-
2008
- 2008-06-18 HK HK08106675.1A patent/HK1116417A1/xx not_active IP Right Cessation
- 2008-07-02 JP JP2008173198A patent/JP2009040767A/ja not_active Ceased
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