|
US20050054048A1
(en)
*
|
2003-07-29 |
2005-03-10 |
Luigi Grasso |
Antibodies and methods for generating genetically altered antibodies with enhanced effector function
|
|
CA2556027C
(en)
|
2004-02-12 |
2015-11-24 |
Morphotek, Inc. |
Monoclonal antibodies that specifically block biological activity of a tumor antigen
|
|
EP2322560B1
(en)
*
|
2005-03-10 |
2013-09-04 |
Morphotek, Inc. |
Anti-mesothelin antibodies
|
|
EP2172487A1
(en)
*
|
2005-04-22 |
2010-04-07 |
Morphotek Inc. |
Antibodies with Immune Effector Activity that Internalize in Folate Receptor Alpha-Positive Cells
|
|
KR100694508B1
(ko)
*
|
2005-05-24 |
2007-03-13 |
울산대학교 산학협력단 |
Ｈｂｂｋ４항체를 포함하는 암 질환 치료용 약학조성물및 이를 이용한 암의 면역치료 방법
|
|
US7943133B2
(en)
|
2006-02-02 |
2011-05-17 |
Boston Biocom Llc |
Mesothelin antibody protein fusions and methods of use
|
|
US7795411B2
(en)
*
|
2006-10-05 |
2010-09-14 |
Fred Hutchinson Cancer Research Center |
Vectors for expressing in vivo biotinylated recombinant proteins
|
|
KR20170012582A
(ko)
*
|
2006-11-02 |
2017-02-02 |
악셀레론 파마 인코포레이티드 |
Ａｌｋ１ 수용체 및 리간드 길항제 및 그의 용도
|
|
HRP20150074T1
(hr)
|
2007-10-01 |
2015-03-13 |
Bristol-Myers Squibb Company |
Humana antitijela koja se vežu za mezotelin i njihove uporabe
|
|
KR101559599B1
(ko)
*
|
2007-11-26 |
2015-10-12 |
바이엘 인텔렉쳐 프로퍼티 게엠베하 |
항-메소텔린 항체 및 이의 용도
|
|
EP2257572A1
(en)
*
|
2008-03-27 |
2010-12-08 |
The Government of the United States of America as represented by The Secretary of the Department of Health and Human Services |
Human anti-mesothelin monoclonal antibodies
|
|
JP2010014691A
(ja)
*
|
2008-06-20 |
2010-01-21 |
Igaku Seibutsugaku Kenkyusho:Kk |
腹水中のメソテリン及び／又は巨核球増強因子を検出するための方法、キット、試薬及び装置
|
|
CA2756393C
(en)
*
|
2009-03-24 |
2017-06-20 |
The Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services |
Anti-mesothelin antibodies
|
|
AR076284A1
(es)
*
|
2009-04-29 |
2011-06-01 |
Bayer Schering Pharma Ag |
Inmunoconjugados de antimesotelina y usos de los mismos
|
|
PL2552961T3
(pl)
*
|
2010-03-30 |
2018-04-30 |
Janssen Biotech, Inc. |
Humanizowane przeciwciała il-25
|
|
AU2011349443B2
(en)
*
|
2010-12-20 |
2015-12-24 |
Genentech, Inc. |
Anti-mesothelin antibodies and immunoconjugates
|
|
US10233240B1
(en)
*
|
2011-04-18 |
2019-03-19 |
The Regents Of The University Of California |
Methods for treating cholestatic liver fibrosis
|
|
EP2704739B1
(en)
|
2011-05-06 |
2017-07-12 |
The Government of the United States of America, as represented by the Secretary of the Department of Health and Human Services |
Recombinant immunotoxin targeting mesothelin
|
|
CN105017420B
(zh)
|
2012-02-17 |
2019-05-28 |
西雅图基因公司 |
针对整联蛋白αvβ6的抗体和使用该抗体治疗癌症
|
|
EP3575311A1
(en)
|
2012-03-20 |
2019-12-04 |
Biogen MA Inc. |
Jcv neutralizing antibodies
|
|
DK2828292T3
(da)
|
2012-03-20 |
2019-01-02 |
Biogen Ma Inc |
Jcv-neutraliserende antistoffer
|
|
CA2868121C
(en)
|
2012-03-23 |
2021-06-01 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Anti-mesothelin chimeric antigen receptors
|
|
WO2014004549A2
(en)
|
2012-06-27 |
2014-01-03 |
Amgen Inc. |
Anti-mesothelin binding proteins
|
|
WO2014031476A1
(en)
*
|
2012-08-21 |
2014-02-27 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Mesothelin domain-specific monoclonal antibodies and use thereof
|
|
RS61010B1
(sr)
|
2014-11-20 |
2020-11-30 |
Hoffmann La Roche |
Bispecifični antigen vezujući molekuli koji aktiviraju t ćelije protiv folr1 i cd3
|
|
ES2808853T3
(es)
|
2014-11-20 |
2021-03-02 |
Hoffmann La Roche |
Cadenas ligeras comunes y procedimientos de uso
|
|
WO2016126608A1
(en)
|
2015-02-02 |
2016-08-11 |
Novartis Ag |
Car-expressing cells against multiple tumor antigens and uses thereof
|
|
EP3770168A1
(en)
|
2015-05-18 |
2021-01-27 |
TCR2 Therapeutics Inc. |
Compositions and methods for tcr reprogramming using fusion proteins
|
|
CN106467573B
(zh)
*
|
2015-08-21 |
2021-05-25 |
佧珐药业有限公司 |
抗间皮素全人抗体以及靶向间皮素的免疫效应细胞
|
|
KR101782487B1
(ko)
|
2015-09-24 |
2017-09-27 |
재단법인 목암생명과학연구소 |
신규 항-메소텔린 항체 및 이를 포함하는 조성물
|
|
US20170096485A1
(en)
*
|
2015-10-02 |
2017-04-06 |
Hoffmann-La Roche Inc. |
Bispecific t cell activating antigen binding molecules
|
|
JP7461620B2
(ja)
|
2015-10-06 |
2024-04-04 |
リージェンツ オブ ザ ユニバーシティ オブ ミネソタ |
治療用化合物及び方法
|
|
KR20180099768A
(ko)
|
2015-12-30 |
2018-09-05 |
노파르티스 아게 |
증진된 효능을 갖는 면역 이펙터 세포 요법
|
|
SG11201807489PA
(en)
|
2016-03-04 |
2018-09-27 |
Novartis Ag |
Cells expressing multiple chimeric antigen receptor (car) molecules and uses therefore
|
|
JP7015244B2
(ja)
|
2016-03-22 |
2022-02-02 |
エフ・ホフマン－ラ・ロシュ・アクチェンゲゼルシャフト |
プロテアーゼ活性化ｔ細胞二重特異性分子
|
|
WO2017162587A1
(en)
*
|
2016-03-22 |
2017-09-28 |
F. Hoffmann-La Roche Ag |
Protease-activated t cell bispecific molecules
|
|
EP3432924A1
(en)
|
2016-03-23 |
2019-01-30 |
Novartis AG |
Cell secreted minibodies and uses thereof
|
|
US20230071283A1
(en)
|
2016-04-15 |
2023-03-09 |
Aimee S. Payne |
Compositions and methods for selective protein expression
|
|
PT3448421T
(pt)
*
|
2016-04-29 |
2022-01-14 |
Univ Leland Stanford Junior |
Métodos e composições para a prevenção e tratamento de aderências cirúrgicas
|
|
KR20190014525A
(ko)
*
|
2016-05-27 |
2019-02-12 |
애브비 바이오테라퓨틱스 인크. |
면역 조절 단백질과 종양 항원을 결합하는 이중특이적 결합 단백질
|
|
SG11201811184UA
(en)
|
2016-06-20 |
2019-01-30 |
F Star Beta Ltd |
Lag -3 binding members
|
|
GB201612520D0
(en)
|
2016-07-19 |
2016-08-31 |
F-Star Beta Ltd |
Binding molecules
|
|
SG11201900885VA
(en)
|
2016-08-01 |
2019-02-27 |
Novartis Ag |
Treatment of cancer using a chimeric antigen receptor in combination with an inhibitor of a pro-m2 macrophage molecule
|
|
WO2018026953A1
(en)
|
2016-08-02 |
2018-02-08 |
TCR2 Therapeutics Inc. |
Compositions and methods for tcr reprogramming using fusion proteins
|
|
BR112019007100A2
(pt)
|
2016-10-07 |
2019-06-25 |
Tcr2 Therapeutics Inc |
composições e métodos para reprogramação de receptores de célula t com o uso de proteínas de fusão
|
|
CN110177803A
(zh)
|
2016-11-22 |
2019-08-27 |
T细胞受体治疗公司 |
用于使用融合蛋白进行tcr重新编程的组合物和方法
|
|
RS67792B1
(sr)
|
2016-12-01 |
2026-03-31 |
Regeneron Pharma |
Radio-obeležena anti-pd-l1 antitela za imuno-pet snimanje
|
|
US11535662B2
(en)
|
2017-01-26 |
2022-12-27 |
Novartis Ag |
CD28 compositions and methods for chimeric antigen receptor therapy
|
|
WO2018232020A1
(en)
|
2017-06-13 |
2018-12-20 |
TCR2 Therapeutics Inc. |
Compositions and methods for tcr reprogramming using fusion proteins
|
|
CA3086098A1
(en)
|
2017-12-19 |
2019-06-27 |
F-Star Beta Limited |
Fc binding fragments comprising a pd-l1 antigen-binding site
|
|
US20210047405A1
(en)
|
2018-04-27 |
2021-02-18 |
Novartis Ag |
Car t cell therapies with enhanced efficacy
|
|
US20210396739A1
(en)
|
2018-05-01 |
2021-12-23 |
Novartis Ag |
Biomarkers for evaluating car-t cells to predict clinical outcome
|
|
US20210213063A1
(en)
|
2018-05-25 |
2021-07-15 |
Novartis Ag |
Combination therapy with chimeric antigen receptor (car) therapies
|
|
WO2019237035A1
(en)
|
2018-06-08 |
2019-12-12 |
Intellia Therapeutics, Inc. |
Compositions and methods for immunooncology
|
|
CA3102036A1
(en)
*
|
2018-06-18 |
2019-12-26 |
Anwita Biosciences, Inc. |
Cytokine fusion proteins and uses thereof
|
|
AR116109A1
(es)
|
2018-07-10 |
2021-03-31 |
Novartis Ag |
Derivados de 3-(5-amino-1-oxoisoindolin-2-il)piperidina-2,6-diona y usos de los mismos
|
|
GB201811415D0
(en)
|
2018-07-12 |
2018-08-29 |
F Star Beta Ltd |
Anti-Mesothelin Anti bodies
|
|
GB201811404D0
(en)
|
2018-07-12 |
2018-08-29 |
F Star Beta Ltd |
Anti-CD137 Antibodies
|
|
AU2019301206B2
(en)
|
2018-07-12 |
2025-10-30 |
Invox Pharma Limited |
Antibody molecules that bind CD137 and OX40
|
|
BR112021000394A2
(pt)
|
2018-07-12 |
2021-04-06 |
F-Star Beta Limited |
Moléculas de anticorpo que se ligam a pd-l1 e cd137
|
|
GB201811410D0
(en)
|
2018-07-12 |
2018-08-29 |
F Star Beta Ltd |
OX40 Binding molecules
|
|
GB201811403D0
(en)
|
2018-07-12 |
2018-08-29 |
F Star Beta Ltd |
Antibody molecules
|
|
GB201811450D0
(en)
|
2018-07-12 |
2018-08-29 |
F Star Delta Ltd |
Mesothelin and CD137 binding molecules
|
|
GB201811408D0
(en)
|
2018-07-12 |
2018-08-29 |
F Star Beta Ltd |
CD137 Binding Molecules
|
|
SG11202101811VA
(en)
|
2018-08-30 |
2021-03-30 |
Tcr2 Therapeutics Inc |
Compositions and methods for tcr reprogramming using fusion proteins
|
|
US12331320B2
(en)
|
2018-10-10 |
2025-06-17 |
The Research Foundation For The State University Of New York |
Genome edited cancer cell vaccines
|
|
CN112912400B
(zh)
|
2018-10-19 |
2025-05-30 |
明尼苏达大学董事会 |
Nk接合子分子及其使用方法
|
|
WO2020092631A1
(en)
*
|
2018-10-31 |
2020-05-07 |
Fred Hutchinson Cancer Research Center |
Compositions and methods for detecting and treating cancers characterized by expression of mesothelin
|
|
AU2019402189B2
(en)
|
2018-12-20 |
2023-04-13 |
Novartis Ag |
Dosing regimen and pharmaceutical combination comprising 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives
|
|
CN112321714B
(zh)
*
|
2019-01-08 |
2022-06-28 |
上海霖科生物科技有限公司 |
与间皮素结合的单克隆抗体及其核酸分子
|
|
CA3123519A1
(en)
|
2019-02-15 |
2020-08-20 |
Novartis Ag |
Substituted 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives and uses thereof
|
|
EP3924054B1
(en)
|
2019-02-15 |
2025-04-02 |
Novartis AG |
3-(1-oxo-5-(piperidin-4-yl)isoindolin-2-yl)piperidine-2,6-dione derivatives and uses thereof
|
|
MX2021015533A
(es)
*
|
2019-06-19 |
2022-02-10 |
Silverback Therapeutics Inc |
Anticuerpos anti-mesotelina e inmunoconjugados de los mismos.
|
|
TWI884192B
(zh)
|
2019-12-05 |
2025-05-21 |
美商西健公司 |
抗αＶβ６抗體及抗體-藥物結合物
|
|
IL293640A
(en)
|
2019-12-20 |
2022-08-01 |
Amgen Inc |
CD40 antagonistic mesothelin-targeted multispecific antibody constructs for the treatment of solid tumors
|
|
US20230057071A1
(en)
|
2019-12-20 |
2023-02-23 |
Novartis Ag |
Combination of anti tim-3 antibody mbg453 and anti tgf-beta antibody nis793, with or without decitabine or the anti pd-1 antibody spartalizumab, for treating myelofibrosis and myelodysplastic syndrome
|
|
US20230332104A1
(en)
|
2020-06-11 |
2023-10-19 |
Novartis Ag |
Zbtb32 inhibitors and uses thereof
|
|
EP4168007A1
(en)
|
2020-06-23 |
2023-04-26 |
Novartis AG |
Dosing regimen comprising 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives
|
|
EP4188549A1
(en)
|
2020-08-03 |
2023-06-07 |
Novartis AG |
Heteroaryl substituted 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives and uses thereof
|
|
TW202304979A
(zh)
|
2021-04-07 |
2023-02-01 |
瑞士商諾華公司 |
抗ＴＧＦβ抗體及其他治療劑用於治療增殖性疾病之用途
|
|
TW202321296A
(zh)
|
2021-10-06 |
2023-06-01 |
美商鏈接免疫療法公司 |
抗間皮素抗原結合分子及其用途
|
|
WO2023214325A1
(en)
|
2022-05-05 |
2023-11-09 |
Novartis Ag |
Pyrazolopyrimidine derivatives and uses thereof as tet2 inhibitors
|
|
WO2024102954A1
(en)
|
2022-11-10 |
2024-05-16 |
Massachusetts Institute Of Technology |
Activation induced clipping system (aics)
|
|
EP4701654A2
(en)
|
2023-04-25 |
2026-03-04 |
Arsenal Biosciences, Inc. |
Novel receptors for transcription regulation
|
|
WO2024243441A1
(en)
|
2023-05-24 |
2024-11-28 |
Kumquat Biosciences Inc. |
Heterocyclic compounds and uses thereof
|
|
WO2025235862A1
(en)
|
2024-05-10 |
2025-11-13 |
Inndura Therapeutics Inc. |
A modified immune cell receptor comprising a target-binding domain and the extracellular domain of cd16a
|
|
WO2026037400A1
(en)
*
|
2024-08-16 |
2026-02-19 |
Wuxi Biologics (Shanghai) Co., Ltd. |
Anti-msln antibodies and uses thereof
|
|
WO2026152120A2
(en)
|
2025-01-13 |
2026-07-16 |
HCW Biologics, Inc. |
Chimeric polypeptides and uses thereof
|