JP2007504280A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2007504280A5 JP2007504280A5 JP2006532897A JP2006532897A JP2007504280A5 JP 2007504280 A5 JP2007504280 A5 JP 2007504280A5 JP 2006532897 A JP2006532897 A JP 2006532897A JP 2006532897 A JP2006532897 A JP 2006532897A JP 2007504280 A5 JP2007504280 A5 JP 2007504280A5
- Authority
- JP
- Japan
- Prior art keywords
- antibody
- ovr110
- cells
- cancer
- pta
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US46955503P | 2003-05-09 | 2003-05-09 | |
| US60/469,555 | 2003-05-09 | ||
| US55295904P | 2004-03-12 | 2004-03-12 | |
| US60/552,959 | 2004-03-12 | ||
| US55646404P | 2004-03-25 | 2004-03-25 | |
| US60/556,464 | 2004-03-25 | ||
| PCT/US2004/014490 WO2004101756A2 (en) | 2003-05-09 | 2004-05-10 | Ovr110 antibody compositions and methods of use |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2007504280A JP2007504280A (ja) | 2007-03-01 |
| JP2007504280A5 true JP2007504280A5 (enExample) | 2007-11-22 |
| JP4884224B2 JP4884224B2 (ja) | 2012-02-29 |
Family
ID=33458763
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006532897A Expired - Fee Related JP4884224B2 (ja) | 2003-05-09 | 2004-05-10 | Ｏｖｒ１１０抗体組成物および使用方法 |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US7619068B2 (enExample) |
| EP (1) | EP1633784B1 (enExample) |
| JP (1) | JP4884224B2 (enExample) |
| AT (1) | ATE516047T1 (enExample) |
| AU (1) | AU2004239301B2 (enExample) |
| CA (1) | CA2525899C (enExample) |
| DK (1) | DK1633784T3 (enExample) |
| IL (1) | IL171797A (enExample) |
| WO (1) | WO2004101756A2 (enExample) |
Families Citing this family (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000012758A1 (en) * | 1998-09-02 | 2000-03-09 | Diadexus Llc | A novel method of diagnosing, monitoring, staging, imaging and treating various cancers |
| EP1539218A4 (en) * | 2002-06-20 | 2007-08-22 | Univ California | COMPOSITIONS AND METHODS FOR MODULATING LYMPHOCYTE ACTIVITY |
| EP1560593B1 (en) | 2002-10-25 | 2016-04-20 | Genentech, Inc. | Novel composition and methods for the treatment of immune related diseases |
| WO2004101756A2 (en) * | 2003-05-09 | 2004-11-25 | Diadexus, Inc. | Ovr110 antibody compositions and methods of use |
| JP5173428B2 (ja) * | 2004-11-10 | 2013-04-03 | ディアデクサス インコーポレーテッド | Ｏｖｒ１１０抗体組成物および使用方法 |
| WO2006054961A2 (en) * | 2004-11-12 | 2006-05-26 | Genentech, Inc. | Novel composition and methods for the treatment of immune related diseases |
| EP2230517A1 (en) | 2005-01-07 | 2010-09-22 | Diadexus, Inc. | OVR110 antibody compositions and methods of use |
| US8759490B2 (en) | 2005-03-24 | 2014-06-24 | Millennium Pharamaceuticals, Inc. | Antibodies that bind OV064 and methods of use therefor |
| US8323645B2 (en) | 2005-03-24 | 2012-12-04 | Millennium Pharmaceuticals, Inc. | Antibodies that bind OV064 and methods of use therefor |
| WO2007067991A2 (en) * | 2005-12-08 | 2007-06-14 | Medarex, Inc. | Human monoclonal antibodies to o8e |
| JP5164855B2 (ja) * | 2006-01-04 | 2013-03-21 | フジレビオ アメリカ、インク． | 子宮内膜または子宮癌を評価するためのｈｅ４及びそのほかの生化学的マーカーの使用 |
| JP5391073B2 (ja) | 2006-11-27 | 2014-01-15 | ディアデクサス インコーポレーテッド | Ｏｖｒ１１０抗体組成物および使用方法 |
| WO2012019061A2 (en) | 2010-08-05 | 2012-02-09 | Stem Centrx, Inc. | Novel effectors and methods of use |
| SG10201506782XA (en) | 2010-08-27 | 2015-10-29 | Stem Centrx Inc | Notum protein modulators and methods of use |
| AU2011295715B9 (en) | 2010-09-03 | 2017-02-23 | Abbvie Stemcentrx Llc | Novel modulators and methods of use |
| NZ611428A (en) | 2010-12-08 | 2015-07-31 | Stemcentrx Inc | Novel modulators and methods of use |
| SA112330278B1 (ar) | 2011-02-18 | 2015-10-09 | ستيم سينتركس، انك. | مواد ضابطة جديدة وطرق للاستخدام |
| US9676854B2 (en) | 2011-08-15 | 2017-06-13 | Medimmune, Llc | Anti-B7-H4 antibodies and their uses |
| US20130058947A1 (en) | 2011-09-02 | 2013-03-07 | Stem Centrx, Inc | Novel Modulators and Methods of Use |
| EP3539985A1 (en) | 2012-02-24 | 2019-09-18 | AbbVie Stemcentrx LLC | Anti sez6 antibodies and methods of use |
| BR112014020826A8 (pt) | 2012-02-24 | 2017-09-19 | Stem Centrx Inc | Anticorpo que se liga especificamente a um epítopo, ácido nucleico, vetor ou célula hospedeira, conjugado de fármaco anticorpo, composição farmacêutica compreendendo o referido anticorpo, uso do mesmo, kit e método de preparação do conjugado |
| KR20150029017A (ko) | 2012-07-10 | 2015-03-17 | 박스터 헬쓰케어 에스에이 | 항-mif 면역조직화학 |
| CA2894879A1 (en) | 2012-12-19 | 2014-06-26 | Amplimmune, Inc. | B7-h4 specific antibodies, and compositions and methods of use thereof |
| ES2731681T3 (es) | 2013-02-22 | 2019-11-18 | Abbvie Stemcentrx Llc | Conjugados de anticuerpo anti-DLL3 y PBD y usos de los mismos |
| JP6436965B2 (ja) * | 2013-03-14 | 2018-12-12 | ジェネンテック， インコーポレイテッド | 抗ｂ７−ｈ４抗体及びイムノコンジュゲート |
| US9562099B2 (en) | 2013-03-14 | 2017-02-07 | Genentech, Inc. | Anti-B7-H4 antibodies and immunoconjugates |
| SG11201601424PA (en) | 2013-08-28 | 2016-03-30 | Stemcentrx Inc | Site-specific antibody conjugation methods and compositions |
| CN105792836A (zh) | 2013-08-28 | 2016-07-20 | 施特姆森特克斯股份有限公司 | 新型sez6调节剂以及应用方法 |
| RU2016122041A (ru) | 2013-11-06 | 2017-12-11 | ЭББВИ СТЕМСЕНТРКС ЭлЭлСи | Новые анти-клаудин антитела и способы их применения |
| CA2939941A1 (en) | 2014-02-21 | 2015-08-27 | Abbvie Stemcentrx Llc | Anti-dll3 antibodies and drug conjugates for use in melanoma |
| RU2708075C2 (ru) | 2014-04-30 | 2019-12-04 | Пфайзер Инк. | Конъюгаты анти-ртк7 антитело-лекарственное средство |
| TW201617368A (zh) | 2014-09-05 | 2016-05-16 | 史坦森特瑞斯公司 | 新穎抗ｍｆｉ２抗體及使用方法 |
| WO2016040724A1 (en) | 2014-09-12 | 2016-03-17 | Genentech, Inc. | Anti-b7-h4 antibodies and immunoconjugates |
| JP2019522960A (ja) | 2016-04-21 | 2019-08-22 | アッヴィ・ステムセントルクス・エル・エル・シー | 新規の抗ｂｍｐｒ１ｂ抗体及び使用方法 |
| EP4649966A3 (en) | 2016-12-01 | 2026-02-18 | Regeneron Pharmaceuticals, Inc. | Radiolabeled anti-pd-l1 antibodies for immuno-pet imaging |
| US11306144B2 (en) | 2017-08-25 | 2022-04-19 | Five Prime Therapeutics, Inc. | B7-H4 antibodies and methods of use thereof |
| CN112566934B (zh) | 2018-01-23 | 2024-09-17 | 奈斯科尔公司 | B7-h4抗体及其使用方法 |
| BR112020016986A2 (pt) | 2018-02-21 | 2021-03-02 | Five Prime Therapeutics, Inc. | formulações de anticorpo contra b7-h4 |
| KR20200144094A (ko) | 2018-03-02 | 2020-12-28 | 파이브 프라임 테라퓨틱스, 인크. | B7-h4 항체 및 이의 사용 방법 |
| CN116172059A (zh) * | 2021-11-29 | 2023-05-30 | 内蒙古伊利实业集团股份有限公司 | 青苹果微胶囊、包含其的发酵乳及发酵乳饮料和制备方法 |
Family Cites Families (53)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3773919A (en) | 1969-10-23 | 1973-11-20 | Du Pont | Polylactide-drug mixtures |
| US3896111A (en) | 1973-02-20 | 1975-07-22 | Research Corp | Ansa macrolides |
| US4151042A (en) | 1977-03-31 | 1979-04-24 | Takeda Chemical Industries, Ltd. | Method for producing maytansinol and its derivatives |
| US4137230A (en) | 1977-11-14 | 1979-01-30 | Takeda Chemical Industries, Ltd. | Method for the production of maytansinoids |
| US4307016A (en) | 1978-03-24 | 1981-12-22 | Takeda Chemical Industries, Ltd. | Demethyl maytansinoids |
| US4265814A (en) | 1978-03-24 | 1981-05-05 | Takeda Chemical Industries | Matansinol 3-n-hexadecanoate |
| JPS5562090A (en) | 1978-10-27 | 1980-05-10 | Takeda Chem Ind Ltd | Novel maytansinoid compound and its preparation |
| US4256746A (en) | 1978-11-14 | 1981-03-17 | Takeda Chemical Industries | Dechloromaytansinoids, their pharmaceutical compositions and method of use |
| JPS55164687A (en) | 1979-06-11 | 1980-12-22 | Takeda Chem Ind Ltd | Novel maytansinoid compound and its preparation |
| JPS55102583A (en) | 1979-01-31 | 1980-08-05 | Takeda Chem Ind Ltd | 20-acyloxy-20-demethylmaytansinoid compound |
| JPS55162791A (en) | 1979-06-05 | 1980-12-18 | Takeda Chem Ind Ltd | Antibiotic c-15003pnd and its preparation |
| JPS55164685A (en) | 1979-06-08 | 1980-12-22 | Takeda Chem Ind Ltd | Novel maytansinoid compound and its preparation |
| JPS55164686A (en) | 1979-06-11 | 1980-12-22 | Takeda Chem Ind Ltd | Novel maytansinoid compound and its preparation |
| US4309428A (en) | 1979-07-30 | 1982-01-05 | Takeda Chemical Industries, Ltd. | Maytansinoids |
| JPS5645483A (en) | 1979-09-19 | 1981-04-25 | Takeda Chem Ind Ltd | C-15003phm and its preparation |
| EP0028683A1 (en) | 1979-09-21 | 1981-05-20 | Takeda Chemical Industries, Ltd. | Antibiotic C-15003 PHO and production thereof |
| JPS5645485A (en) | 1979-09-21 | 1981-04-25 | Takeda Chem Ind Ltd | Production of c-15003pnd |
| WO1982001188A1 (en) | 1980-10-08 | 1982-04-15 | Takeda Chemical Industries Ltd | 4,5-deoxymaytansinoide compounds and process for preparing same |
| US4450254A (en) | 1980-11-03 | 1984-05-22 | Standard Oil Company | Impact improvement of high nitrile resins |
| US4315929A (en) | 1981-01-27 | 1982-02-16 | The United States Of America As Represented By The Secretary Of Agriculture | Method of controlling the European corn borer with trewiasine |
| US4313946A (en) | 1981-01-27 | 1982-02-02 | The United States Of America As Represented By The Secretary Of Agriculture | Chemotherapeutically active maytansinoids from Trewia nudiflora |
| JPS57192389A (en) | 1981-05-20 | 1982-11-26 | Takeda Chem Ind Ltd | Novel maytansinoid |
| DD266710A3 (de) | 1983-06-06 | 1989-04-12 | Ve Forschungszentrum Biotechnologie | Verfahren zur biotechnischen Herstellung van alkalischer Phosphatase |
| US4892538A (en) | 1987-11-17 | 1990-01-09 | Brown University Research Foundation | In vivo delivery of neurotransmitters by implanted, encapsulated cells |
| US5283187A (en) | 1987-11-17 | 1994-02-01 | Brown University Research Foundation | Cell culture-containing tubular capsule produced by co-extrusion |
| US5208020A (en) | 1989-10-25 | 1993-05-04 | Immunogen Inc. | Cytotoxic agents comprising maytansinoids and their therapeutic use |
| CA2026147C (en) | 1989-10-25 | 2006-02-07 | Ravi J. Chari | Cytotoxic agents comprising maytansinoids and their therapeutic use |
| US7018809B1 (en) | 1991-09-19 | 2006-03-28 | Genentech, Inc. | Expression of functional antibody fragments |
| EP0646178A1 (en) | 1992-06-04 | 1995-04-05 | The Regents Of The University Of California | expression cassette with regularoty regions functional in the mammmlian host |
| DK0752248T3 (da) | 1992-11-13 | 2000-11-13 | Idec Pharma Corp | Terapeutisk anvendelse af kimæriske og radioaktivt mærkede antistoffer mod humant B-lymfocytbegrænset differentieringsantig |
| PT616812E (pt) | 1993-03-24 | 2000-04-28 | Berlex Biosciences | Combinacao de compostos anti-hormonais e moleculas de ligacao no tratamento do cancro |
| US5910486A (en) | 1994-09-06 | 1999-06-08 | Uab Research Foundation | Methods for modulating protein function in cells using, intracellular antibody homologues |
| US5789199A (en) | 1994-11-03 | 1998-08-04 | Genentech, Inc. | Process for bacterial production of polypeptides |
| US5840523A (en) | 1995-03-01 | 1998-11-24 | Genetech, Inc. | Methods and compositions for secretion of heterologous polypeptides |
| AR013269A1 (es) | 1997-08-04 | 2000-12-13 | Scras | Producto que contiene por lo menos un rna de doble filamento combinado con por lo menos un agente anti-viral, para la utilizacion terapeutica en eltratamiento de una enfermedad viral, en especial de la hepatitis viral |
| US6506559B1 (en) | 1997-12-23 | 2003-01-14 | Carnegie Institute Of Washington | Genetic inhibition by double-stranded RNA |
| CA2328895A1 (en) | 1998-06-02 | 1999-12-09 | Genentech, Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
| GB9827152D0 (en) | 1998-07-03 | 1999-02-03 | Devgen Nv | Characterisation of gene function using double stranded rna inhibition |
| WO2000012758A1 (en) * | 1998-09-02 | 2000-03-09 | Diadexus Llc | A novel method of diagnosing, monitoring, staging, imaging and treating various cancers |
| US6468546B1 (en) * | 1998-12-17 | 2002-10-22 | Corixa Corporation | Compositions and methods for therapy and diagnosis of ovarian cancer |
| US20020119158A1 (en) * | 1998-12-17 | 2002-08-29 | Corixa Corporation | Compositions and methods for the therapy and diagnosis of ovarian cancer |
| CA2361201A1 (en) | 1999-01-28 | 2000-08-03 | Medical College Of Georgia Research Institute, Inc. | Composition and method for in vivo and in vitro attenuation of gene expression using double stranded rna |
| HK1047109A1 (zh) | 1999-10-15 | 2003-02-07 | University Of Massachusetts | 作为指定基因干预工具的rna干预轨迹基因 |
| GB9927444D0 (en) | 1999-11-19 | 2000-01-19 | Cancer Res Campaign Tech | Inhibiting gene expression |
| AU2625501A (en) | 1999-12-30 | 2001-07-16 | Rutgers, The State University Of New Jersey | Compositions and methods for gene silencing |
| EP1272630A2 (en) | 2000-03-16 | 2003-01-08 | Genetica, Inc. | Methods and compositions for rna interference |
| ES2336887T5 (es) | 2000-03-30 | 2019-03-06 | Whitehead Inst Biomedical Res | Mediadores de interferencia por ARN específicos de secuencias de ARN |
| JP2003531588A (ja) | 2000-04-11 | 2003-10-28 | ジェネンテック・インコーポレーテッド | 多価抗体とその用途 |
| WO2002002624A2 (en) | 2000-06-30 | 2002-01-10 | Amgen, Inc. | B7-like molecules and uses thereof |
| CA2429814C (en) | 2000-12-01 | 2014-02-18 | Thomas Tuschl | Rna interference mediating small rna molecules |
| AU2002258518A1 (en) * | 2001-03-14 | 2002-09-24 | Millennium Pharmaceuticals, Inc. | Nucleic acid molecules and proteins for the identification, assessment, prevention, and therapy of ovarian cancer |
| WO2004101756A2 (en) * | 2003-05-09 | 2004-11-25 | Diadexus, Inc. | Ovr110 antibody compositions and methods of use |
| JP5391073B2 (ja) * | 2006-11-27 | 2014-01-15 | ディアデクサス インコーポレーテッド | Ｏｖｒ１１０抗体組成物および使用方法 |
-
2004
- 2004-05-10 WO PCT/US2004/014490 patent/WO2004101756A2/en not_active Ceased
- 2004-05-10 JP JP2006532897A patent/JP4884224B2/ja not_active Expired - Fee Related
- 2004-05-10 US US10/557,331 patent/US7619068B2/en not_active Expired - Lifetime
- 2004-05-10 EP EP04760956A patent/EP1633784B1/en not_active Expired - Lifetime
- 2004-05-10 DK DK04760956.5T patent/DK1633784T3/da active
- 2004-05-10 AT AT04760956T patent/ATE516047T1/de active
- 2004-05-10 CA CA2525899A patent/CA2525899C/en not_active Expired - Lifetime
- 2004-05-10 AU AU2004239301A patent/AU2004239301B2/en not_active Ceased
-
2005
- 2005-11-06 IL IL171797A patent/IL171797A/en active IP Right Grant
-
2009
- 2009-10-09 US US12/576,313 patent/US20100209438A1/en not_active Abandoned
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2007504280A5 (enExample) | ||
| Sun et al. | CD44+/CD24− breast cancer cells isolated from MCF-7 cultures exhibit enhanced angiogenic properties | |
| Cheng et al. | MORAb-202, an antibody–drug conjugate utilizing humanized anti-human FRα farletuzumab and the microtubule-targeting agent eribulin, has potent antitumor activity | |
| JP6491701B2 (ja) | 新規モジュレーターと使用の方法 | |
| CA2185043C (en) | Monoclonal antibodies recognizing tie-receptor and their use | |
| JP2021151263A (ja) | シアリル−Ｌｅｗｉｓ ａに対するヒト抗体をコードする核酸 | |
| JP2010510809A5 (enExample) | ||
| RU2007133108A (ru) | АНТИТЕЛА, СВЯЗЫВАЮЩИЕСЯ С EphA2, И МЕТОДЫ ИХ ИСПОЛЬЗОВАНИЯ | |
| JP2005538701A5 (enExample) | ||
| CN111183156A (zh) | 用于用抗cd19/cd20免疫治疗来治疗癌症的组合物和方法 | |
| JP2008546780A5 (enExample) | ||
| JP2012100677A5 (enExample) | ||
| JP2017500028A (ja) | 新規の抗ｄｐｅｐ３抗体および使用方法 | |
| RU2015108348A (ru) | Антитела, связывающиеся с лизилоксидазоподобным ферментом-2 (loxl2), и способы их применения | |
| JP2006507013A5 (enExample) | ||
| CA2595610A1 (en) | Antibodies directed to angiopoietin-2 and uses thereof | |
| KR20140027051A (ko) | 인간 프로스타글란딘 e2 수용체 ep4 에 대한 항체 | |
| JP2008537673A5 (enExample) | ||
| JP2021528047A5 (enExample) | ||
| JP2014515600A5 (enExample) | ||
| JP2011509246A5 (enExample) | ||
| CN119421897A (zh) | 抗ror1抗体 | |
| JP2007516226A5 (enExample) | ||
| JP2008500833A5 (enExample) | ||
| De Santis et al. | Low and high tenascin-expressing tumors are efficiently targeted by ST2146 monoclonal antibody |