JP2008538289A5 - - Google Patents

Info

Publication number

JP2008538289A5

JP2008538289A5 JP2008506789A JP2008506789A JP2008538289A5 JP 2008538289 A5 JP2008538289 A5 JP 2008538289A5 JP 2008506789 A JP2008506789 A JP 2008506789A JP 2008506789 A JP2008506789 A JP 2008506789A JP 2008538289 A5 JP2008538289 A5 JP 2008538289A5

Authority

JP

Japan

Prior art keywords

antibody

seq

acid sequence

cancer

amino acid

Prior art date

2006-04-14

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Granted

Links

• Espacenet
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• 102000036639 antigens Human genes 0.000 claims 12
• 108091007433 antigens Proteins 0.000 claims 12
• 206010028980 Neoplasm Diseases 0.000 claims 10
• 125000003275 alpha amino acid group Chemical group 0.000 claims 10
• 201000011510 cancer Diseases 0.000 claims 10
• 239000000427 antigen Substances 0.000 claims 8
• 150000007523 nucleic acids Chemical group 0.000 claims 6
• 206010009944 Colon cancer Diseases 0.000 claims 5
• 208000001333 Colorectal Neoplasms Diseases 0.000 claims 5
• 206010061902 Pancreatic neoplasm Diseases 0.000 claims 5
• 208000015486 malignant pancreatic neoplasm Diseases 0.000 claims 5
• 201000002528 pancreatic cancer Diseases 0.000 claims 5
• 208000008443 pancreatic carcinoma Diseases 0.000 claims 5
• 108091028043 Nucleic acid sequence Proteins 0.000 claims 4
• 239000012634 fragment Substances 0.000 claims 4
• 239000000463 material Substances 0.000 claims 3
• 239000002773 nucleotide Substances 0.000 claims 3
• 125000003729 nucleotide group Chemical group 0.000 claims 3
• 101100080277 Caenorhabditis elegans ncr-1 gene Proteins 0.000 claims 2
• 101100459404 Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) npc-1 gene Proteins 0.000 claims 2
• 229940127089 cytotoxic agent Drugs 0.000 claims 2
• 239000002254 cytotoxic agent Substances 0.000 claims 2
• 231100000599 cytotoxic agent Toxicity 0.000 claims 2
• 239000013604 expression vector Substances 0.000 claims 2
• 238000000034 method Methods 0.000 claims 2
• 108020004707 nucleic acids Proteins 0.000 claims 2
• 102000039446 nucleic acids Human genes 0.000 claims 2
• FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 1
• 230000003302 anti-idiotype Effects 0.000 claims 1
• 230000000259 anti-tumor effect Effects 0.000 claims 1
• 239000002184 metal Substances 0.000 claims 1
• 239000008194 pharmaceutical composition Substances 0.000 claims 1
• 230000002285 radioactive effect Effects 0.000 claims 1