PL3894012T4 - Postacie krystaliczne i postacie soli inhibitora kinazy - Google Patents
Postacie krystaliczne i postacie soli inhibitora kinazyInfo
- Publication number
- PL3894012T4 PL3894012T4 PL19836338.4T PL19836338T PL3894012T4 PL 3894012 T4 PL3894012 T4 PL 3894012T4 PL 19836338 T PL19836338 T PL 19836338T PL 3894012 T4 PL3894012 T4 PL 3894012T4
- Authority
- PL
- Poland
- Prior art keywords
- forms
- kinase inhibitor
- salt
- crystalline
- crystalline forms
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862779430P | 2018-12-13 | 2018-12-13 | |
| US201962856469P | 2019-06-03 | 2019-06-03 | |
| PCT/US2019/065972 WO2020123800A1 (en) | 2018-12-13 | 2019-12-12 | Crystalline forms and salt forms of a kinase inhibitor |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PL3894012T4 true PL3894012T4 (pl) | 2026-01-05 |
| PL3894012T3 PL3894012T3 (pl) | 2026-01-05 |
Family
ID=69160358
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL19836338.4T PL3894012T3 (pl) | 2018-12-13 | 2019-12-12 | Postacie krystaliczne i postacie soli inhibitora kinazy |
Country Status (33)
| Country | Link |
|---|---|
| US (2) | US12017995B2 (pl) |
| EP (2) | EP3894012B1 (pl) |
| JP (3) | JP7509779B2 (pl) |
| KR (2) | KR102828472B1 (pl) |
| CN (1) | CN113329790A (pl) |
| AU (2) | AU2019395419B2 (pl) |
| BR (1) | BR112021011333A2 (pl) |
| CA (1) | CA3122840A1 (pl) |
| CL (1) | CL2021001537A1 (pl) |
| CO (1) | CO2021007613A2 (pl) |
| CR (1) | CR20210375A (pl) |
| DK (1) | DK3894012T3 (pl) |
| ES (1) | ES3052838T3 (pl) |
| FI (1) | FI3894012T3 (pl) |
| GE (1) | GEP20247596B (pl) |
| HR (1) | HRP20251122T1 (pl) |
| HU (1) | HUE072868T2 (pl) |
| IL (2) | IL320433A (pl) |
| LT (1) | LT3894012T (pl) |
| MA (1) | MA54458B1 (pl) |
| MD (1) | MD3894012T2 (pl) |
| MX (1) | MX2021006951A (pl) |
| PE (1) | PE20211757A1 (pl) |
| PH (1) | PH12021551356A1 (pl) |
| PL (1) | PL3894012T3 (pl) |
| PT (1) | PT3894012T (pl) |
| RS (1) | RS67216B1 (pl) |
| SG (1) | SG11202105949RA (pl) |
| SI (1) | SI3894012T1 (pl) |
| SM (1) | SMT202500346T1 (pl) |
| TW (1) | TWI852963B (pl) |
| WO (1) | WO2020123800A1 (pl) |
| ZA (1) | ZA202103844B (pl) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MY210421A (en) * | 2018-01-26 | 2025-09-22 | Exelixis Inc | Compounds for the treatment of kinase-dependent disorders |
| GEAP202415849A (en) * | 2019-06-03 | 2024-03-11 | Exelixis Inc | Crystalline salt forms of kinase inhibitor |
| KR20230005190A (ko) * | 2020-04-30 | 2023-01-09 | 엑셀리시스, 인코포레이티드 | 키나제억제제의 제조 공정 |
| AU2021318134A1 (en) | 2020-07-31 | 2023-03-02 | Exelixis, Inc. | Combinations for the treatment of cancer |
| PE20240223A1 (es) * | 2020-11-05 | 2024-02-16 | Exelixis Inc | Composiciones farmaceuticas de un inhibidor de cinasa |
| CN112650176B (zh) * | 2020-12-22 | 2022-08-30 | 天能化工有限公司 | 一种盐酸解析开停车工序的dcs控制方法 |
| TW202334090A (zh) * | 2021-11-03 | 2023-09-01 | 美商艾克塞里克斯公司 | 用於治療激酶依賴性病症之化合物 |
| WO2023122739A1 (en) | 2021-12-22 | 2023-06-29 | Exelixis, Inc. | Crystalline forms and salt forms of a kinase inhibitor |
| CN116751161A (zh) * | 2023-06-28 | 2023-09-15 | 中国人民解放军军事科学院军事医学研究院 | 喹啉类化合物及其制备方法、药物组合物及医药用途 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2392565B1 (en) * | 2003-09-26 | 2014-03-19 | Exelixis, Inc. | c-Met modulators and methods of use |
| CA2604238C (en) | 2005-04-15 | 2015-07-07 | Neogenix Oncology, Inc. | Recombinant monoclonal antibodies and corresponding antigens for colon and pancreatic cancers |
| AU2009303602B2 (en) | 2008-10-14 | 2012-06-14 | Sunshine Lake Pharma Co., Ltd. | Compounds and methods of use |
| RS52754B2 (sr) | 2009-01-16 | 2022-08-31 | Exelixis Inc | Malat so n-(4- {[6,7-bis(metiloksi)hinolin-4-il]oksi}fenil-n'- (4-fluorofenil) ciklopropan-1,1-dikarboksamid-a, i njeni kristalni oblici za lečenje karcinoma |
| CN102408411B (zh) | 2011-09-19 | 2014-10-22 | 北京康辰药业股份有限公司 | 一种含喹啉基的羟肟酸类化合物及其制备方法、以及含有该化合物的药物组合物及其应用 |
| CA2886433C (en) | 2012-10-04 | 2022-01-04 | Dana-Farber Cancer Institute, Inc. | Human monoclonal anti-pd-l1 antibodies and methods of use |
| KR102243062B1 (ko) | 2013-05-02 | 2021-04-21 | 아납티스바이오, 아이엔씨. | 예정된 사멸-1에 대한 항체 |
| EP3738952A1 (en) | 2014-02-14 | 2020-11-18 | Exelixis, Inc. | Crystalline solid forms of n-{4-[(6,7-dimethoxyquinolin-4-yl)oxy]phenyl}-n'-(4-fluorophenyl) cyclopropane-1,1-dicarboxamide, processes for making, and methods of use |
| CN104817497B (zh) | 2015-03-20 | 2017-03-08 | 南京众睿缘生物科技有限公司 | 一种炔代喹啉衍生物及其制备方法和用途 |
| CA3060370A1 (en) * | 2017-05-26 | 2018-11-29 | Exelixis, Inc. | Crystalline solid forms of salts of n-{4-[(6,7-dimethoxyquinolin-4-yl)oxy]phenyl}-n'-(4-fluorophenyl) cyclopropane-1,1-dicarboxamide, processes for making, and methods of use |
| MY210421A (en) * | 2018-01-26 | 2025-09-22 | Exelixis Inc | Compounds for the treatment of kinase-dependent disorders |
| GEAP202415849A (en) * | 2019-06-03 | 2024-03-11 | Exelixis Inc | Crystalline salt forms of kinase inhibitor |
-
2019
- 2019-12-12 PL PL19836338.4T patent/PL3894012T3/pl unknown
- 2019-12-12 LT LTEPPCT/US2019/065972T patent/LT3894012T/lt unknown
- 2019-12-12 AU AU2019395419A patent/AU2019395419B2/en active Active
- 2019-12-12 KR KR1020217021734A patent/KR102828472B1/ko active Active
- 2019-12-12 CR CR20210375A patent/CR20210375A/es unknown
- 2019-12-12 CN CN201980090041.5A patent/CN113329790A/zh active Pending
- 2019-12-12 MA MA54458A patent/MA54458B1/fr unknown
- 2019-12-12 WO PCT/US2019/065972 patent/WO2020123800A1/en not_active Ceased
- 2019-12-12 DK DK19836338.4T patent/DK3894012T3/da active
- 2019-12-12 IL IL320433A patent/IL320433A/en unknown
- 2019-12-12 CA CA3122840A patent/CA3122840A1/en active Pending
- 2019-12-12 US US17/312,658 patent/US12017995B2/en active Active
- 2019-12-12 ES ES19836338T patent/ES3052838T3/es active Active
- 2019-12-12 KR KR1020257021669A patent/KR20250103803A/ko active Pending
- 2019-12-12 EP EP19836338.4A patent/EP3894012B1/en active Active
- 2019-12-12 JP JP2021533537A patent/JP7509779B2/ja active Active
- 2019-12-12 RS RS20250909A patent/RS67216B1/sr unknown
- 2019-12-12 IL IL283860A patent/IL283860B2/en unknown
- 2019-12-12 HR HRP20251122TT patent/HRP20251122T1/hr unknown
- 2019-12-12 HU HUE19836338A patent/HUE072868T2/hu unknown
- 2019-12-12 SM SM20250346T patent/SMT202500346T1/it unknown
- 2019-12-12 SG SG11202105949RA patent/SG11202105949RA/en unknown
- 2019-12-12 PT PT198363384T patent/PT3894012T/pt unknown
- 2019-12-12 PE PE2021000862A patent/PE20211757A1/es unknown
- 2019-12-12 EP EP25183289.5A patent/EP4631505A3/en active Pending
- 2019-12-12 GE GEAP201915695A patent/GEP20247596B/en unknown
- 2019-12-12 BR BR112021011333-9A patent/BR112021011333A2/pt unknown
- 2019-12-12 FI FIEP19836338.4T patent/FI3894012T3/fi active
- 2019-12-12 MX MX2021006951A patent/MX2021006951A/es unknown
- 2019-12-12 SI SI201930963T patent/SI3894012T1/sl unknown
- 2019-12-12 MD MDE20211022T patent/MD3894012T2/ro unknown
- 2019-12-13 TW TW108145868A patent/TWI852963B/zh active
-
2021
- 2021-06-04 ZA ZA2021/03844A patent/ZA202103844B/en unknown
- 2021-06-09 PH PH12021551356A patent/PH12021551356A1/en unknown
- 2021-06-10 CO CONC2021/0007613A patent/CO2021007613A2/es unknown
- 2021-06-11 CL CL2021001537A patent/CL2021001537A1/es unknown
-
2023
- 2023-12-27 JP JP2023221085A patent/JP7783870B2/ja active Active
-
2024
- 2024-05-07 US US18/657,052 patent/US20240300897A1/en active Pending
-
2025
- 2025-09-22 AU AU2025234277A patent/AU2025234277A1/en active Pending
- 2025-11-28 JP JP2025208367A patent/JP2026031599A/ja active Pending
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