SG11202105949RA - Crystalline forms and salt forms of a kinase inhibitor - Google Patents

Crystalline forms and salt forms of a kinase inhibitor

Info

Publication number
SG11202105949RA
SG11202105949RA SG11202105949RA SG11202105949RA SG11202105949RA SG 11202105949R A SG11202105949R A SG 11202105949RA SG 11202105949R A SG11202105949R A SG 11202105949RA SG 11202105949R A SG11202105949R A SG 11202105949RA SG 11202105949R A SG11202105949R A SG 11202105949RA
Authority
SG
Singapore
Prior art keywords
forms
kinase inhibitor
salt
crystalline
crystalline forms
Prior art date
Application number
SG11202105949RA
Inventor
Frenel Demorin
Khalid Shah
Sagar Shakya
Peter Wong
Courtney Johnson
Melanie Bevill
Stephan Parent
Original Assignee
Exelixis Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Exelixis Inc filed Critical Exelixis Inc
Publication of SG11202105949RA publication Critical patent/SG11202105949RA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13Crystalline forms, e.g. polymorphs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
SG11202105949RA 2018-12-13 2019-12-12 Crystalline forms and salt forms of a kinase inhibitor SG11202105949RA (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862779430P 2018-12-13 2018-12-13
US201962856469P 2019-06-03 2019-06-03
PCT/US2019/065972 WO2020123800A1 (en) 2018-12-13 2019-12-12 Crystalline forms and salt forms of a kinase inhibitor

Publications (1)

Publication Number Publication Date
SG11202105949RA true SG11202105949RA (en) 2021-07-29

Family

ID=69160358

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202105949RA SG11202105949RA (en) 2018-12-13 2019-12-12 Crystalline forms and salt forms of a kinase inhibitor

Country Status (19)

Country Link
EP (1) EP3894012A1 (en)
JP (2) JP2022512399A (en)
KR (1) KR20210102381A (en)
CN (1) CN113329790A (en)
AU (1) AU2019395419A1 (en)
BR (1) BR112021011333A2 (en)
CA (1) CA3122840A1 (en)
CL (1) CL2021001537A1 (en)
CO (1) CO2021007613A2 (en)
CR (1) CR20210375A (en)
GE (1) GEP20247596B (en)
IL (1) IL283860A (en)
MA (1) MA54458A (en)
MX (1) MX2021006951A (en)
PE (1) PE20211757A1 (en)
PH (1) PH12021551356A1 (en)
SG (1) SG11202105949RA (en)
TW (1) TW202039440A (en)
WO (1) WO2020123800A1 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CR20200358A (en) * 2018-01-26 2021-02-22 Exelixis Inc Compounds for the treatment of kinase-dependent disorders
WO2021222673A1 (en) * 2020-04-30 2021-11-04 Exelixis, Inc. Processes for the preparation of a kinase inhibitor
CN116437954A (en) 2020-07-31 2023-07-14 埃克塞里艾克西斯公司 Combination for the treatment of cancer
CA3196001A1 (en) 2020-11-05 2022-05-12 Exelixis, Inc. Pharmaceutical compositions of a kinase inhibitor
CN112650176B (en) * 2020-12-22 2022-08-30 天能化工有限公司 DCS control method for hydrochloric acid analysis start-stop process
TW202334090A (en) * 2021-11-03 2023-09-01 美商艾克塞里克斯公司 Compounds for the treatment of kinase-dependent disorders
CA3240202A1 (en) 2021-12-22 2023-06-29 Kirsten Phizackerley Crystalline forms and salt forms of a kinase inhibitor

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4638436B2 (en) * 2003-09-26 2011-02-23 エグゼリクシス, インコーポレイテッド c-Met modulators and uses thereof
WO2006113546A2 (en) 2005-04-15 2006-10-26 Neogenix Oncology, Inc. Recombinant monoclonal antibodies and corresponding antigens for colon and pancreatic cancers
CN107892719B (en) 2012-10-04 2022-01-14 达纳-法伯癌症研究所公司 Human monoclonal anti-PD-L1 antibodies and methods of use
CN105339389B (en) 2013-05-02 2021-04-27 安奈普泰斯生物有限公司 Antibodies against programmed death-1 (PD-1)
CR20200358A (en) * 2018-01-26 2021-02-22 Exelixis Inc Compounds for the treatment of kinase-dependent disorders

Also Published As

Publication number Publication date
CO2021007613A2 (en) 2021-06-21
CL2021001537A1 (en) 2022-02-04
CA3122840A1 (en) 2020-06-18
BR112021011333A2 (en) 2021-08-31
MX2021006951A (en) 2021-07-15
EP3894012A1 (en) 2021-10-20
US20230029213A1 (en) 2023-01-26
KR20210102381A (en) 2021-08-19
JP2022512399A (en) 2022-02-03
CR20210375A (en) 2021-08-18
GEP20247596B (en) 2024-02-26
JP2024038167A (en) 2024-03-19
PE20211757A1 (en) 2021-09-07
CN113329790A (en) 2021-08-31
AU2019395419A1 (en) 2021-07-01
WO2020123800A1 (en) 2020-06-18
MA54458A (en) 2021-10-20
TW202039440A (en) 2020-11-01
IL283860A (en) 2021-07-29
PH12021551356A1 (en) 2021-12-06

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