|
US5292668A
(en)
|
1981-12-21 |
1994-03-08 |
Boston Biomedical Research Institute, Inc. |
Bispecific antibody determinants
|
|
US5869620A
(en)
|
1986-09-02 |
1999-02-09 |
Enzon, Inc. |
Multivalent antigen-binding proteins
|
|
US5260203A
(en)
|
1986-09-02 |
1993-11-09 |
Enzon, Inc. |
Single polypeptide chain binding molecules
|
|
FR2604092B1
(fr)
|
1986-09-19 |
1990-04-13 |
Immunotech Sa |
Immunoreactifs destines a cibler les cellules animales pour leur visualisation ou leur destruction in vivo
|
|
DE3852036T2
(de)
|
1987-07-27 |
1995-03-09 |
Commonwealth Scientific And Industrial Research Organization, Campbell |
Rezeptormembranen.
|
|
US4943525A
(en)
|
1987-11-02 |
1990-07-24 |
Bioventures, Inc. |
Simultaneous immunoassay for the determination of antigens and antibodies
|
|
US5869053A
(en)
|
1988-03-04 |
1999-02-09 |
Cancer Research Campaign Technology, Ltd. |
5T4 antigen from human trophoblasts
|
|
US4892824A
(en)
|
1988-03-15 |
1990-01-09 |
Synbiotics Corporation |
Fast track method for producing monoclonal bi-specific immunoglobulins
|
|
US6010902A
(en)
|
1988-04-04 |
2000-01-04 |
Bristol-Meyers Squibb Company |
Antibody heteroconjugates and bispecific antibodies for use in regulation of lymphocyte activity
|
|
US5851527A
(en)
|
1988-04-18 |
1998-12-22 |
Immunomedics, Inc. |
Method for antibody targeting of therapeutic agents
|
|
FI903489A0
(fi)
|
1988-11-11 |
1990-07-10 |
Medical Res Council |
Ligander med en enda sektion, receptorer innehaollande naemnda ligander, foerfaranden foer deras framstaellning samt anvaendning av liganderna och receptorerna.
|
|
DE3920358A1
(de)
|
1989-06-22 |
1991-01-17 |
Behringwerke Ag |
Bispezifische und oligospezifische, mono- und oligovalente antikoerperkonstrukte, ihre herstellung und verwendung
|
|
US5980896A
(en)
|
1989-06-30 |
1999-11-09 |
Bristol-Myers Squibb Company |
Antibodies reactive with human carcinomas
|
|
US5332567A
(en)
|
1989-08-24 |
1994-07-26 |
Immunomedics |
Detection and treatment of infections with immunoconjugates
|
|
US5582996A
(en)
|
1990-12-04 |
1996-12-10 |
The Wistar Institute Of Anatomy & Biology |
Bifunctional antibodies and method of preparing same
|
|
US6197298B1
(en)
|
1991-04-19 |
2001-03-06 |
Tanox, Inc. |
Modified binding molecules specific for T lymphocytes and their use as in vivo immune modulators in animals
|
|
DE4118120A1
(de)
|
1991-06-03 |
1992-12-10 |
Behringwerke Ag |
Tetravalente bispezifische rezeptoren, ihre herstellung und verwendung
|
|
US5637481A
(en)
|
1993-02-01 |
1997-06-10 |
Bristol-Myers Squibb Company |
Expression vectors encoding bispecific fusion proteins and methods of producing biologically active bispecific fusion proteins in a mammalian cell
|
|
DE4134982A1
(de)
|
1991-10-23 |
1993-04-29 |
Kernforschungsz Karlsruhe |
Verwendung von antikoerper enthaltenden praeparationen zur immunsuppression
|
|
US5932448A
(en)
|
1991-11-29 |
1999-08-03 |
Protein Design Labs., Inc. |
Bispecific antibody heterodimers
|
|
DE4140142A1
(de)
|
1991-12-05 |
1993-06-09 |
Boehringer Mannheim Gmbh, 6800 Mannheim, De |
Multivalentes dextranreagenz zum einsatz in praezipitationstests
|
|
CA2125396A1
(en)
|
1991-12-10 |
1993-06-24 |
Wayne A. Marasco |
Reactive neutralizing human anti-gp 120 recombinant antibody, dna coding the same and use thereof
|
|
EP1291360A1
(en)
|
1991-12-13 |
2003-03-12 |
Xoma Corporation |
Methods and materials for preparation of modified antibody variable domains and therapeutic uses thereof
|
|
FR2686899B1
(fr)
|
1992-01-31 |
1995-09-01 |
Rhone Poulenc Rorer Sa |
Nouveaux polypeptides biologiquement actifs, leur preparation et compositions pharmaceutiques les contenant.
|
|
DE69333807T2
(de)
|
1992-02-06 |
2006-02-02 |
Chiron Corp., Emeryville |
Marker für krebs und biosynthetisches bindeprotein dafür
|
|
US5965132A
(en)
|
1992-03-05 |
1999-10-12 |
Board Of Regents, The University Of Texas System |
Methods and compositions for targeting the vasculature of solid tumors
|
|
US6096289A
(en)
|
1992-05-06 |
2000-08-01 |
Immunomedics, Inc. |
Intraoperative, intravascular, and endoscopic tumor and lesion detection, biopsy and therapy
|
|
US20080152586A1
(en)
|
1992-09-25 |
2008-06-26 |
Avipep Pty Limited |
High avidity polyvalent and polyspecific reagents
|
|
CA2145278C
(en)
|
1992-09-25 |
2009-03-10 |
Commonwealth Scientific And Industrial Research Organisation |
Target binding polypeptide
|
|
WO1994008038A1
(en)
|
1992-10-02 |
1994-04-14 |
Trustees Of Dartmouth College |
Bispecific reagents for redirected targeting of low density lipoprotein
|
|
US5837821A
(en)
|
1992-11-04 |
1998-11-17 |
City Of Hope |
Antibody construct
|
|
US6953668B1
(en)
|
1992-11-05 |
2005-10-11 |
Sloan-Kettering Institute For Cancer Research |
Prostate-specific membrane antigen
|
|
US7105159B1
(en)
|
1992-11-05 |
2006-09-12 |
Sloan-Kettering Institute For Cancer Research |
Antibodies to prostate-specific membrane antigen
|
|
JP4204642B2
(ja)
|
1992-11-05 |
2009-01-07 |
スローン − ケタリング・インスティテュート・フォー・キャンサー・リサーチ |
前立腺に特異的な膜抗原
|
|
US7070782B1
(en)
|
1992-11-05 |
2006-07-04 |
Sloan-Kettering Institute For Cancer Research |
Prostate-specific membrane antigen
|
|
AU5670194A
(en)
|
1992-11-20 |
1994-06-22 |
Enzon, Inc. |
Linker for linked fusion polypeptides
|
|
US5376249A
(en)
|
1992-11-25 |
1994-12-27 |
Perseptive Biosystems, Inc. |
Analysis utilizing isoelectric focusing
|
|
DK0672142T3
(da)
|
1992-12-04 |
2001-06-18 |
Medical Res Council |
Multivalente og multispecifikke bindingsproteiner samt fremstilling og anvendelse af disse
|
|
GB9225453D0
(en)
|
1992-12-04 |
1993-01-27 |
Medical Res Council |
Binding proteins
|
|
SG55079A1
(en)
|
1992-12-11 |
1998-12-21 |
Dow Chemical Co |
Multivalent single chain antibodies
|
|
US5861156A
(en)
|
1993-01-08 |
1999-01-19 |
Creative Biomolecules |
Methods of delivering agents to target cells
|
|
US5705614A
(en)
|
1993-04-09 |
1998-01-06 |
Chiron Corporation |
Methods of producing antigen forks
|
|
US6491916B1
(en)
|
1994-06-01 |
2002-12-10 |
Tolerance Therapeutics, Inc. |
Methods and materials for modulation of the immunosuppresive activity and toxicity of monoclonal antibodies
|
|
UA40577C2
(uk)
*
|
1993-08-02 |
2001-08-15 |
Мерк Патент Гмбх |
Біспецифічна молекула, що використовується для лізису пухлинних клітин, спосіб її одержання, моноклональне антитіло (варіанти), фармацевтичний препарат, фармацевтичний набір (варіанти), спосіб видалення пухлинних клітин
|
|
US5869049A
(en)
|
1993-09-02 |
1999-02-09 |
Trustees Of Dartmouth College |
Methods of inducing T cell unresponsiveness to bone marrow with gp39 antagonists
|
|
KR100398819B1
(ko)
|
1993-09-02 |
2004-02-05 |
트러스티스 오브 다트마우스 칼리지 |
gp39길항제를포함하는약제조성물
|
|
US5935818A
(en)
|
1995-02-24 |
1999-08-10 |
Sloan-Kettering Institute For Cancer Research |
Isolated nucleic acid molecule encoding alternatively spliced prostate-specific membrane antigen and uses thereof
|
|
US6569432B1
(en)
|
1995-02-24 |
2003-05-27 |
Sloan-Kettering Institute For Cancer Research |
Prostate-specific membrane antigen and uses thereof
|
|
GB9324807D0
(en)
|
1993-12-03 |
1994-01-19 |
Cancer Res Campaign Tech |
Tumour antibody
|
|
DE4421391C1
(de)
|
1994-06-18 |
1995-11-30 |
Gsf Forschungszentrum Umwelt |
Verwendung von Antikörpern gegen T-Zellen zur verlängerten Immunsuppression
|
|
US5559099A
(en)
|
1994-09-08 |
1996-09-24 |
Genvec, Inc. |
Penton base protein and methods of using same
|
|
US5541087A
(en)
|
1994-09-14 |
1996-07-30 |
Fuji Immunopharmaceuticals Corporation |
Expression and export technology of proteins as immunofusins
|
|
US5688690A
(en)
|
1994-09-16 |
1997-11-18 |
The Wistar Institute Of Anatomy And Biology |
Human cytotoxic lymphocyte signal transduction surface protein (P38) and monoclonal antibodies thereto
|
|
EP0812356B1
(en)
|
1995-02-24 |
2006-02-08 |
Sloan-Kettering Institute For Cancer Research |
Prostate-specific membrane antigen and uses thereof
|
|
US5731168A
(en)
|
1995-03-01 |
1998-03-24 |
Genentech, Inc. |
Method for making heteromultimeric polypeptides
|
|
GB9504344D0
(en)
|
1995-03-03 |
1995-04-19 |
Unilever Plc |
Antibody fragment production
|
|
US5747035A
(en)
|
1995-04-14 |
1998-05-05 |
Genentech, Inc. |
Polypeptides with increased half-life for use in treating disorders involving the LFA-1 receptor
|
|
US6096871A
(en)
|
1995-04-14 |
2000-08-01 |
Genentech, Inc. |
Polypeptides altered to contain an epitope from the Fc region of an IgG molecule for increased half-life
|
|
US6121022A
(en)
|
1995-04-14 |
2000-09-19 |
Genentech, Inc. |
Altered polypeptides with increased half-life
|
|
AUPO591797A0
(en)
|
1997-03-27 |
1997-04-24 |
Commonwealth Scientific And Industrial Research Organisation |
High avidity polyvalent and polyspecific reagents
|
|
US5773292A
(en)
|
1995-06-05 |
1998-06-30 |
Cornell University |
Antibodies binding portions, and probes recognizing an antigen of prostate epithelial cells but not antigens circulating in the blood
|
|
US5830478A
(en)
|
1995-06-07 |
1998-11-03 |
Boston Biomedical Research Institute |
Method for delivering functional domains of diphtheria toxin to a cellular target
|
|
US5989830A
(en)
|
1995-10-16 |
1999-11-23 |
Unilever Patent Holdings Bv |
Bifunctional or bivalent antibody fragment analogue
|
|
JP2001501801A
(ja)
|
1995-10-19 |
2001-02-13 |
ブリストル−マイヤーズ スクイッブ カンパニー |
モノクローナル抗体ｂｒ１１０およびその使用
|
|
US20040253246A1
(en)
|
1996-02-23 |
2004-12-16 |
Israeli Ron S. |
Prostate-specific membrane antigen and uses thereof
|
|
ATE318147T1
(de)
|
1996-03-25 |
2006-03-15 |
Medarex Inc |
Spezifische monoklonale antikörperfür die extrazelluläre domäne von protasta-spezifischem membranantigen
|
|
US6150508A
(en)
|
1996-03-25 |
2000-11-21 |
Northwest Biotherapeutics, Inc. |
Monoclonal antibodies specific for the extracellular domain of prostate-specific membrane antigen
|
|
US6136311A
(en)
|
1996-05-06 |
2000-10-24 |
Cornell Research Foundation, Inc. |
Treatment and diagnosis of cancer
|
|
US6107090A
(en)
|
1996-05-06 |
2000-08-22 |
Cornell Research Foundation, Inc. |
Treatment and diagnosis of prostate cancer with antibodies to extracellur PSMA domains
|
|
ATE247830T1
(de)
|
1996-05-23 |
2003-09-15 |
Inverness Medical Switzerland |
Verbesserungen in oder in bezug auf spezifische bindungsassays
|
|
JP2000515735A
(ja)
|
1996-07-03 |
2000-11-28 |
ジェネンテック インコーポレーテッド |
肝細胞成長因子レセプターアゴニスト
|
|
GB9712818D0
(en)
|
1996-07-08 |
1997-08-20 |
Cambridge Antibody Tech |
Labelling and selection of specific binding molecules
|
|
US5922845A
(en)
|
1996-07-11 |
1999-07-13 |
Medarex, Inc. |
Therapeutic multispecific compounds comprised of anti-Fcα receptor antibodies
|
|
EP0932417B1
(en)
|
1996-10-17 |
2003-03-05 |
Immunomedics, Inc. |
Non-antigenic toxin-conjugate and fusion protein of internalizing receptor system
|
|
CA2389358C
(en)
|
1996-12-31 |
2008-07-15 |
Genometrix Incorporated |
Multiplexed molecular analysis apparatus and method
|
|
US6541212B2
(en)
|
1997-03-10 |
2003-04-01 |
The Regents Of The University Of California |
Methods for detecting prostate stem cell antigen protein
|
|
EP0977837A1
(en)
|
1997-04-03 |
2000-02-09 |
Universite Laval |
Transgenic expression in genital tract and sexual accessory glands
|
|
US6368596B1
(en)
|
1997-07-08 |
2002-04-09 |
Board Of Regents, The University Of Texas System |
Compositions and methods for homoconjugates of antibodies which induce growth arrest or apoptosis of tumor cells
|
|
US6977074B2
(en)
|
1997-07-10 |
2005-12-20 |
Mannkind Corporation |
Method of inducing a CTL response
|
|
US6994851B1
(en)
|
1997-07-10 |
2006-02-07 |
Mannkind Corporation |
Method of inducing a CTL response
|
|
ATE353864T1
(de)
|
1997-09-03 |
2007-03-15 |
Immunomedics Inc |
Fluorierung von proteinen und peptiden für positronemissionstomographie
|
|
US6030792A
(en)
|
1997-11-13 |
2000-02-29 |
Pfizer Inc |
Assays for measurement of protein fragments in biological media
|
|
US6709844B1
(en)
|
2000-11-16 |
2004-03-23 |
Mannkind Corporation |
Avoidance of undesirable replication intermediates in plasmid propagation
|
|
DE19911329A1
(de)
|
1998-03-27 |
2000-09-21 |
Benes Ivan Friedrich |
Humantherapeutisch anwendbares Radioimmunkonjugat und Verfahren zu seiner Herstellung
|
|
CZ121599A3
(cs)
|
1998-04-09 |
1999-10-13 |
Aventis Pharma Deutschland Gmbh |
Jednořetězcová molekula vázající několik antigenů, způsob její přípravy a léčivo obsahující tuto molekulu
|
|
ES2434961T5
(es)
|
1998-04-20 |
2018-01-18 |
Roche Glycart Ag |
Ingeniería de glicosilación de anticuerpos para mejorar la citotoxicidad celular dependiente del anticuerpo
|
|
US6200765B1
(en)
|
1998-05-04 |
2001-03-13 |
Pacific Northwest Cancer Foundation |
Non-invasive methods to detect prostate cancer
|
|
US6071490A
(en)
|
1998-05-07 |
2000-06-06 |
Immunomedics, Inc. |
Position emission tomography using gallium-68 chelates
|
|
US6458933B1
(en)
|
1998-05-20 |
2002-10-01 |
Immunomedics, Inc. |
Therapeutic using a bispecific antibody
|
|
US20030149531A1
(en)
|
2000-12-06 |
2003-08-07 |
Hubert Rene S. |
Serpentine transmembrane antigens expressed in human cancers and uses thereof
|
|
US20040141975A1
(en)
|
1998-06-01 |
2004-07-22 |
Raitano Arthur B. |
Nucleic acid and corresponding protein entitled 98P4B6 useful in treatment and detection of cancer
|
|
EP2080802B1
(en)
|
1998-06-01 |
2017-03-29 |
Agensys, Inc. |
Novel serpentine transmembrane antigens expressed in human cancers and uses thereof
|
|
US6833438B1
(en)
|
1999-06-01 |
2004-12-21 |
Agensys, Inc. |
Serpentine transmembrane antigens expressed in human cancers and uses thereof
|
|
US20060052321A1
(en)
|
2002-04-05 |
2006-03-09 |
Raitano Arthur B |
Nucleic acid and corresponding protein entitled 98P4B6 useful in treatment and detection of cancer
|
|
EP1098665B9
(en)
|
1998-07-13 |
2003-08-13 |
The Board Of Regents, The University Of Texas System |
Cancer treatment methods using therapeutic conjugates that bind to aminophospholipids
|
|
AU5815699A
(en)
|
1998-09-08 |
2000-03-27 |
Urocor, Inc. |
Prostate specific promoter and regulation of gene expression
|
|
US6361774B1
(en)
|
1999-09-17 |
2002-03-26 |
Immunomedics, Inc. |
Methods and compositions for increasing the target-specific toxicity of a chemotherapy drug
|
|
DE69928556T2
(de)
|
1998-09-29 |
2006-08-10 |
The Uab Research Foundation, Birmingham |
Immunmodulation mittels genetischer modifikation von dendritischen zellen und b-zellen
|
|
US6835866B1
(en)
|
1998-12-10 |
2004-12-28 |
Board Of Regents, The University Of Texas Systems |
Compositions and methods of modulating cholesterol metabolism
|
|
CA2370237A1
(en)
|
1999-04-13 |
2000-10-19 |
Northwest Biotherapeutics, Inc. |
Methods for the diagnosis and treatment of metastatic prostate tumors
|
|
ES2223705T3
(es)
|
1999-04-28 |
2005-03-01 |
Board Of Regents, The University Of Texas System |
Composiciones y metodos para el tratamiento de cancer mediante inhibi cion selectiva del vegf.
|
|
WO2001009303A2
(en)
|
1999-07-30 |
2001-02-08 |
Vical Inc. |
Flt-3 LIGAND-ENCODING POLYNUCLEOTIDE AS A POLYNUCLEOTIDE-BASED VACCINE ENHANCER
|
|
NZ523206A
(en)
|
1999-08-31 |
2004-12-24 |
Genentech Inc |
Antibodies that bind to tumor gene sequences
|
|
US6342587B1
(en)
|
1999-10-22 |
2002-01-29 |
Ludwig Institute For Cancer Research |
A33 antigen specific immunoglobulin products and uses thereof
|
|
US6824780B1
(en)
|
1999-10-29 |
2004-11-30 |
Genentech, Inc. |
Anti-tumor antibody compositions and methods of use
|
|
EP1268550A2
(en)
|
2000-03-17 |
2003-01-02 |
Boehringer Ingelheim Pharma KG |
Human fap-alpha-specific antibodies
|
|
US20040038339A1
(en)
|
2000-03-24 |
2004-02-26 |
Peter Kufer |
Multifunctional polypeptides comprising a binding site to an epitope of the nkg2d receptor complex
|
|
US6573096B1
(en)
|
2000-04-01 |
2003-06-03 |
The Research Foundation At State University Of New York |
Compositions and methods for inhibition of cancer invasion and angiogenesis
|
|
ES2637801T3
(es)
|
2000-04-11 |
2017-10-17 |
Genentech, Inc. |
Anticuerpos multivalentes y usos de los mismos
|
|
US6861234B1
(en)
|
2000-04-28 |
2005-03-01 |
Mannkind Corporation |
Method of epitope discovery
|
|
CA2405363A1
(en)
|
2000-04-28 |
2001-11-08 |
Ctl Immunotherapies Corp. |
Epitope synchronization in antigen presenting cells
|
|
US6375991B1
(en)
|
2000-09-08 |
2002-04-23 |
Albemarle Corporation |
Production of concentrated biocidal solutions
|
|
DE10045591A1
(de)
|
2000-09-15 |
2002-04-04 |
Klaus Pfizenmaier |
Ortsspezifische, antikörpervermittelte Aktivierung proapoptotischer Zytokine - AMAIZe (Antibody-Mediated Apoptosis Inducing Zytokine)
|
|
ATE535258T1
(de)
|
2001-06-01 |
2011-12-15 |
Cornell Res Foundation Inc |
Modifizierte antikörper gegen prostata- spezifisches membranantigen und ihre verwendungen
|
|
US7666414B2
(en)
|
2001-06-01 |
2010-02-23 |
Cornell Research Foundation, Inc. |
Methods for treating prostate cancer using modified antibodies to prostate-specific membrane antigen
|
|
US7514078B2
(en)
|
2001-06-01 |
2009-04-07 |
Cornell Research Foundation, Inc. |
Methods of treating prostate cancer with anti-prostate specific membrane antigen antibodies
|
|
RU2321630C2
(ru)
|
2001-08-03 |
2008-04-10 |
Гликарт Биотекнолоджи АГ |
Гликозилированные антитела (варианты), обладающие повышенной антителозависимой клеточной цитотоксичностью
|
|
CN1142183C
(zh)
*
|
2001-08-23 |
2004-03-17 |
北京大学人民医院 |
抗独特型微抗体及其制备方法和应用
|
|
EP2287186B1
(en)
|
2001-09-06 |
2014-12-31 |
Agensys, Inc. |
Nucleic acid and corresponding protein entitled STEAP-1 useful in treatment and detection of cancer
|
|
US7494646B2
(en)
|
2001-09-06 |
2009-02-24 |
Agensys, Inc. |
Antibodies and molecules derived therefrom that bind to STEAP-1 proteins
|
|
JP2005527474A
(ja)
|
2001-09-20 |
2005-09-15 |
コーネル リサーチ ファンデーション インコーポレーテッド |
前立腺特異的膜抗原に特異的な結合剤を用いて、皮膚障害を治療するかまたは防止するための方法および組成物
|
|
US20030157108A1
(en)
|
2001-10-25 |
2003-08-21 |
Genentech, Inc. |
Glycoprotein compositions
|
|
GB0126378D0
(en)
|
2001-11-02 |
2002-01-02 |
Oxford Biomedica Ltd |
Antigen
|
|
DE60238864D1
(de)
|
2001-11-07 |
2011-02-17 |
Mankind Corp |
Für epitope von antigenen kodierende expressionsvektoren und verfahren zu deren konzeption
|
|
US20040018519A1
(en)
|
2001-11-16 |
2004-01-29 |
Wright ,Jr. George L |
Methods and devices for quantitative detection of prostate specific membrane antigen and other prostatic markers
|
|
WO2003062375A2
(en)
|
2001-12-19 |
2003-07-31 |
Genentech, Inc. |
Stabilizing polypeptides which have been exposed to urea
|
|
ATE417858T1
(de)
|
2002-02-05 |
2009-01-15 |
Genentech Inc |
Proteinaufreinigung
|
|
AU2003234706A1
(en)
|
2002-04-15 |
2003-11-03 |
Human Genome Sciences, Inc. |
Antibodies that specifically bind to tl5
|
|
AU2003265235A1
(en)
|
2002-04-26 |
2003-12-19 |
Genetech, Inc. |
Non-affinity purification of proteins
|
|
US20050276812A1
(en)
|
2004-06-01 |
2005-12-15 |
Genentech, Inc. |
Antibody-drug conjugates and methods
|
|
AU2003278161A1
(en)
|
2002-06-21 |
2004-01-06 |
Johns Hopkins University School Of Medicine |
Membrane associated tumor endothelium markers
|
|
US9809654B2
(en)
|
2002-09-27 |
2017-11-07 |
Vaccinex, Inc. |
Targeted CD1d molecules
|
|
US7820166B2
(en)
|
2002-10-11 |
2010-10-26 |
Micromet Ag |
Potent T cell modulating molecules
|
|
US9701754B1
(en)
|
2002-10-23 |
2017-07-11 |
City Of Hope |
Covalent disulfide-linked diabodies and uses thereof
|
|
PL222222B1
(pl)
|
2003-01-22 |
2016-07-29 |
Glycart Biotechnology Ag |
Sposób wytwarzania polipeptydu
|
|
US20050026178A1
(en)
|
2003-03-28 |
2005-02-03 |
Marit Nilsen-Hamilton |
Allosteric probes and methods
|
|
GB0308988D0
(en)
|
2003-04-17 |
2003-05-28 |
Univ Singapore |
Molecule
|
|
US7541442B2
(en)
|
2003-05-30 |
2009-06-02 |
Agensys, Inc. |
Antibodies and related molecules that bind to PSCA proteins
|
|
CA2526274C
(en)
|
2003-05-30 |
2015-12-01 |
Agensys, Inc. |
Prostate stem cell antigen (psca) variants and subsequences thereof
|
|
US7595379B2
(en)
|
2003-05-30 |
2009-09-29 |
Agensys, Inc. |
Antibodies and related molecules that bind to PSCA proteins
|
|
CA2523716C
(en)
|
2003-05-31 |
2014-11-25 |
Micromet Ag |
Human anti-human cd3 binding molecules
|
|
US20050163782A1
(en)
|
2003-06-27 |
2005-07-28 |
Biogen Idec Ma Inc. |
Modified binding molecules comprising connecting peptides
|
|
PT3095793T
(pt)
|
2003-07-28 |
2020-05-04 |
Genentech Inc |
Redução da lixiviação de proteína a durante a cromatografia por afinidade com proteína a
|
|
GB0321805D0
(en)
|
2003-09-18 |
2003-10-15 |
Univ Wales Medicine |
Human tumour growth patterns
|
|
US7524813B2
(en)
|
2003-10-10 |
2009-04-28 |
Novo Nordisk Health Care Ag |
Selectively conjugated peptides and methods of making the same
|
|
JP4948174B2
(ja)
|
2003-10-16 |
2012-06-06 |
マイクロメット アクツィエン ゲゼルシャフト |
多重特異的脱免疫ｃｄ３−結合物質
|
|
ES2428358T3
(es)
|
2003-10-17 |
2013-11-07 |
Novo Nordisk A/S |
Terapia de combinación
|
|
ITPD20030264A1
(it)
|
2003-10-30 |
2005-04-30 |
Xeptagen Spa |
Metodo di diagnosi altamente specifico per neoplasie
|
|
CN107213469A
(zh)
|
2003-11-06 |
2017-09-29 |
西雅图基因公司 |
能够与配体偶联的单甲基缬氨酸化合物
|
|
US7235641B2
(en)
|
2003-12-22 |
2007-06-26 |
Micromet Ag |
Bispecific antibodies
|
|
EP1704228B1
(en)
|
2004-01-16 |
2012-04-11 |
Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. |
Immunokinases
|
|
ZA200606410B
(en)
|
2004-02-16 |
2007-12-27 |
Micromet Ag |
Less immunogenic binding molecules
|
|
EP1718667B1
(en)
|
2004-02-23 |
2013-01-09 |
Genentech, Inc. |
Heterocyclic self-immolative linkers and conjugates
|
|
EP1610818A4
(en)
|
2004-03-03 |
2007-09-19 |
Millennium Pharm Inc |
MODIFIED ANTIBODIES AGAINST A PROSTATE-SPECIFIC MEMBRANE-ANTIGEN AND USE THEREOF
|
|
EP1740954B1
(en)
|
2004-04-07 |
2015-08-19 |
Genentech, Inc. |
Mass spectrometry of antibody conjugates
|
|
CA2563735C
(en)
|
2004-04-22 |
2020-07-14 |
Agensys, Inc. |
Antibodies and molecules derived therefrom that bind to steap-1 proteins
|
|
US20080227736A1
(en)
|
2004-06-03 |
2008-09-18 |
Regents Of The University Of California, |
Targeting Pseudotyped Retroviral Vectors
|
|
US20060159689A1
(en)
|
2004-06-17 |
2006-07-20 |
Chih-Sheng Chiang |
Combinations of tumor-associated antigens in diagnostics for various types of cancers
|
|
EA010374B1
(ru)
|
2004-07-16 |
2008-08-29 |
Микромет Аг |
Полипептиды с повышенной экспрессией
|
|
US20100111856A1
(en)
|
2004-09-23 |
2010-05-06 |
Herman Gill |
Zirconium-radiolabeled, cysteine engineered antibody conjugates
|
|
KR101270829B1
(ko)
|
2004-09-23 |
2013-06-07 |
제넨테크, 인크. |
시스테인 유전자조작 항체 및 접합체
|
|
US20070134243A1
(en)
|
2004-12-01 |
2007-06-14 |
Gazzard Lewis J |
Antibody drug conjugates and methods
|
|
US7947839B2
(en)
|
2004-12-01 |
2011-05-24 |
Genentech, Inc. |
Heterocyclic-substituted bis-1,8 naphthalimide compounds, antibody drug conjugates, and methods of use
|
|
CA2491067A1
(en)
|
2004-12-24 |
2006-06-24 |
Stichting Katholieke Universiteit |
Mrna rations in urinary sediments and/or urine as a prognostic marker for prostate cancer
|
|
JP2008528668A
(ja)
*
|
2005-02-03 |
2008-07-31 |
アンチトープ リミテッド |
ヒト抗体及びタンパク質
|
|
EP1869084A2
(en)
*
|
2005-03-04 |
2007-12-26 |
Biogen Idec MA Inc. |
Methods of humanizing immunoglobulin variable regions through rational modification of complementarity determining residues
|
|
CN1854295A
(zh)
*
|
2005-04-25 |
2006-11-01 |
上海新生源医药研究有限公司 |
卵巢癌抗独特型微抗体的生产方法
|
|
GB2426581A
(en)
|
2005-05-27 |
2006-11-29 |
Univ Nottingham |
Immunoassay methods
|
|
EP1726650A1
(en)
*
|
2005-05-27 |
2006-11-29 |
Universitätsklinikum Freiburg |
Monoclonal antibodies and single chain antibody fragments against cell-surface prostate specific membrane antigen
|
|
JP2007014267A
(ja)
|
2005-07-07 |
2007-01-25 |
Toyama Univ |
Ｂ型肝炎ウイルスのＨＢｓ抗原に対するモノクローナル抗体、それに関連する遺伝子およびペプチド、並びにＢ型肝炎ウイルスの検定方法、Ｂ型肝炎の診断方法、治療方法
|
|
US20080279850A1
(en)
|
2005-07-25 |
2008-11-13 |
Trubion Pharmaceuticals, Inc. |
B-Cell Reduction Using CD37-Specific and CD20-Specific Binding Molecules
|
|
ES2460517T3
(es)
|
2005-07-25 |
2014-05-13 |
Emergent Product Development Seattle, Llc |
Reducción de células b mediante el uso de moléculas de unión específica a cd37 y de unión específica a cd20
|
|
US7612181B2
(en)
|
2005-08-19 |
2009-11-03 |
Abbott Laboratories |
Dual variable domain immunoglobulin and uses thereof
|
|
US20090226465A1
(en)
|
2005-10-31 |
2009-09-10 |
Jackson David Y |
Macrocyclic depsipeptide antibody-drug conjugates and methods
|
|
US20070212331A1
(en)
|
2006-03-07 |
2007-09-13 |
Baldassare Joseph J |
Methods and compositions for selectively killing cells
|
|
JP2009531324A
(ja)
*
|
2006-03-20 |
2009-09-03 |
ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア |
癌標的化のための操作された抗前立腺幹細胞抗原（ｐｓｃａ）抗体
|
|
WO2007109747A2
(en)
|
2006-03-21 |
2007-09-27 |
Wyeth |
Methods and compositions for antagonism of rage
|
|
EP2007435B1
(en)
|
2006-03-31 |
2019-12-18 |
Massachusetts Institute Of Technology |
System for targeted delivery of therapeutic agents
|
|
US7566276B2
(en)
|
2006-04-14 |
2009-07-28 |
Dogleg Right Corporation |
Multi-piece putter head having an insert
|
|
US20110052697A1
(en)
|
2006-05-17 |
2011-03-03 |
Gwangju Institute Of Science & Technology |
Aptamer-Directed Drug Delivery
|
|
CN101632020B
(zh)
|
2006-09-13 |
2013-11-27 |
昂西免疫有限公司 |
改进的免疫测定方法
|
|
EP2076292A2
(en)
|
2006-10-25 |
2009-07-08 |
Koninklijke Philips Electronics N.V. |
Contrast agents for detecting prostate cancer
|
|
US8163886B2
(en)
|
2006-12-21 |
2012-04-24 |
Emd Millipore Corporation |
Purification of proteins
|
|
US8362217B2
(en)
|
2006-12-21 |
2013-01-29 |
Emd Millipore Corporation |
Purification of proteins
|
|
EP2144930A1
(en)
|
2007-04-18 |
2010-01-20 |
ZymoGenetics, Inc. |
Single chain fc, methods of making and methods of treatment
|
|
KR20100021601A
(ko)
*
|
2007-05-14 |
2010-02-25 |
바이오겐 아이덱 엠에이 인코포레이티드 |
단일-쇄 Ｆｃ(ＳｃＦｃ) 부분, 이를 포함하는 결합 폴리펩타이드, 및 이에 관련된 방법
|
|
WO2009017823A2
(en)
*
|
2007-08-01 |
2009-02-05 |
The Government Of The United States Of America, As Represented By The Secretary, Department Of Health Of Human Services, National Institutes Of Health |
A fold-back diabody diphtheria toxin immunotoxin and methods of use
|
|
WO2009032949A2
(en)
*
|
2007-09-04 |
2009-03-12 |
The Regents Of The University Of California |
High affinity anti-prostate stem cell antigen (psca) antibodies for cancer targeting and detection
|
|
US7867483B2
(en)
|
2007-10-18 |
2011-01-11 |
Bn Immunotherapeutics, Inc. |
Use of MVA to treat prostate cancer
|
|
AU2008316224A1
(en)
|
2007-10-25 |
2009-04-30 |
Viventia Biotechnologies Inc. |
Antibodies against a cancer-associated epitope of variant HnRNPG and uses thereof
|
|
US9107858B2
(en)
|
2007-12-05 |
2015-08-18 |
Wisconsin Alumni Research Foundation |
Dendritic cell targeting compositions and uses thereof
|
|
EP2250201B1
(en)
|
2008-01-29 |
2014-04-30 |
Ludwig Institute for Cancer Research Ltd. |
Membrane transporter napi2b (slc34a2) epitope for antibody therapy, antibodies directed thereto, and target for cancer therapy
|
|
ES2547552T3
(es)
|
2008-02-01 |
2015-10-07 |
Genentech, Inc. |
Metabolito de nemorrubicina y reactivos análogos, conjugados anticuerpo-fármaco y métodos
|
|
US8043830B2
(en)
|
2008-02-01 |
2011-10-25 |
The Regents Of The University Of California |
Biotin-ligase system for secretion of biotinylated protein
|
|
ITTO20080313A1
(it)
*
|
2008-04-22 |
2009-10-23 |
Marco Colombatti |
Anticorpo monoclonale isolato o suo frammento legante l'antigene specifico di membrana della prostata, suoi coniugati e suoi usi
|
|
TW200947474A
(en)
|
2008-05-05 |
2009-11-16 |
Ren-Huan Pan |
Manufacturing equipment and method of quadratic arc alignment dua-turret formation center, and miniature milliohm current sensors manufactured thereof
|
|
WO2009140242A1
(en)
|
2008-05-13 |
2009-11-19 |
Genentech, Inc. |
Analysis of antibody drug conjugates by bead-based affinity capture and mass spectrometry
|
|
JP6067222B2
(ja)
|
2008-07-15 |
2017-01-25 |
ジェネンテック， インコーポレイテッド |
アントラサイクリン誘導体コンジュゲート、その調製方法及び抗腫瘍化合物としてのその用途
|
|
US20100069616A1
(en)
|
2008-08-06 |
2010-03-18 |
The Regents Of The University Of California |
Engineered antibody-nanoparticle conjugates
|
|
BRPI0918587B1
(pt)
|
2008-09-08 |
2020-10-13 |
Conocophillips Company |
processo e instalação para liquefazer um fluxo de gás natural
|
|
WO2010037397A1
(en)
|
2008-10-01 |
2010-04-08 |
Dako Denmark A/S |
Mhc multimers in cmv immune monitoring
|
|
EA032828B1
(ru)
|
2008-10-10 |
2019-07-31 |
Аптево Рисёрч Энд Девелопмент Ллс |
Иммунотерапевтические средства против комплекса tcr
|
|
US20110207155A1
(en)
|
2008-10-13 |
2011-08-25 |
Xeptagen Spa |
Method for the preparation of immunoconjugates and use thereof
|
|
BRPI0919882A8
(pt)
|
2008-10-30 |
2017-09-19 |
Caris Life Sciences Luxembourg Holdings |
Métodos para avaliar padrões de rna
|
|
CN107254538A
(zh)
|
2008-11-12 |
2017-10-17 |
卡里斯生命科学瑞士控股有限责任公司 |
使用外来体来确定表现型的方法和系统
|
|
EP2358390A1
(en)
|
2008-11-13 |
2011-08-24 |
Emergent Product Development Seattle, LLC |
Cd37 immunotherapeutic combination therapies and uses thereof
|
|
US20110020327A1
(en)
|
2008-12-16 |
2011-01-27 |
Millipore Corporation |
Purification of proteins
|
|
JP5432132B2
(ja)
|
2008-12-25 |
2014-03-05 |
東海ゴム工業株式会社 |
流体封入式防振装置
|
|
EP3543256A1
(en)
|
2009-01-12 |
2019-09-25 |
Cytomx Therapeutics Inc. |
Modified antibody compositions, methods of making and using thereof
|
|
WO2010096486A1
(en)
*
|
2009-02-17 |
2010-08-26 |
Cornell Research Foundation, Inc. |
Methods and kits for diagnosis of cancer and prediction of therapeutic value
|
|
WO2010102195A2
(en)
|
2009-03-06 |
2010-09-10 |
The Johns Hopkins University |
Annexin a11 and associated genes as biomarkers for cancer
|
|
EP2995953B1
(en)
|
2009-03-24 |
2017-11-29 |
Biocept, Inc. |
Devices and methods of cell capture and analysis
|
|
CN102458442B
(zh)
*
|
2009-04-08 |
2016-06-29 |
加利福尼亚大学董事会 |
具有受控血清药代动力学的人蛋白支架
|
|
CN102459346B
(zh)
|
2009-04-27 |
2016-10-26 |
昂考梅德药品有限公司 |
制造异源多聚体分子的方法
|
|
WO2010136481A1
(en)
|
2009-05-28 |
2010-12-02 |
Glaxo Group Limited |
Il-13 binding protein
|
|
SG176947A1
(en)
|
2009-07-03 |
2012-01-30 |
Avipep Pty Ltd |
Immuno-conjugates and methods for producing them
|
|
WO2011003171A1
(en)
|
2009-07-08 |
2011-01-13 |
Smart Technologies Ulc |
Three-dimensional widget manipulation on a multi-touch panel
|
|
TWM383852U
(en)
|
2009-07-13 |
2010-07-01 |
Speedtech Corp |
An improvement of the universal serial bus connector
|
|
JPWO2011043061A1
(ja)
|
2009-10-05 |
2013-03-04 |
キヤノン株式会社 |
光音響イメージング用造影剤、及び、それを用いた光音響イメージング方法
|
|
EP2506876B1
(en)
|
2009-12-02 |
2016-10-12 |
Imaginab, Inc. |
J591 minibodies and cys-diabodies for targeting human prostate specific membrane antigen (psma) and methods for their use
|
|
EP2516462B1
(en)
|
2009-12-23 |
2015-05-06 |
Avipep Pty Ltd |
Immuno-conjugates and methods for producing them
|
|
SG181952A1
(en)
|
2009-12-29 |
2012-07-30 |
Emergent Product Dev Seattle |
Heterodimer binding proteins and uses thereof
|
|
KR20130056855A
(ko)
|
2010-03-01 |
2013-05-30 |
카리스 라이프 사이언스 룩셈부르크 홀딩스 |
치료진단용 생물학적 지표들
|
|
UA108227C2
(xx)
*
|
2010-03-03 |
2015-04-10 |
|
Антигензв'язуючий білок
|
|
US9812638B2
(en)
|
2010-03-19 |
2017-11-07 |
Globalfoundries Inc. |
Backend of line (BEOL) compatible high current density access device for high density arrays of electronic components
|
|
US20120144110A1
(en)
|
2010-12-02 |
2012-06-07 |
Lsi Corporation |
Methods and structure for storage migration using storage array managed server agents
|