JP2008528678A5 - - Google Patents
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- JP2008528678A5 JP2008528678A5 JP2007553747A JP2007553747A JP2008528678A5 JP 2008528678 A5 JP2008528678 A5 JP 2008528678A5 JP 2007553747 A JP2007553747 A JP 2007553747A JP 2007553747 A JP2007553747 A JP 2007553747A JP 2008528678 A5 JP2008528678 A5 JP 2008528678A5
- Authority
- JP
- Japan
- Prior art keywords
- formulation
- connexin
- subject
- administered
- vascular
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US65007505P | 2005-02-03 | 2005-02-03 | |
| US60/650,075 | 2005-02-03 | ||
| PCT/IB2006/001961 WO2006134494A2 (en) | 2005-02-03 | 2006-02-03 | Anti-connexin compounds and therapeutic uses thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012047133A Division JP2012107065A (ja) | 2005-02-03 | 2012-03-02 | 抗コネキシン化合物およびそれらの使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2008528678A JP2008528678A (ja) | 2008-07-31 |
| JP2008528678A5 true JP2008528678A5 (https=) | 2009-03-12 |
| JP5964538B2 JP5964538B2 (ja) | 2016-08-03 |
Family
ID=37532679
Family Applications (6)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007553747A Expired - Fee Related JP5964538B2 (ja) | 2005-02-03 | 2006-02-03 | 抗コネキシン化合物およびそれらの使用 |
| JP2012047133A Withdrawn JP2012107065A (ja) | 2005-02-03 | 2012-03-02 | 抗コネキシン化合物およびそれらの使用 |
| JP2014121150A Withdrawn JP2014169325A (ja) | 2005-02-03 | 2014-06-12 | 抗コネキシン化合物およびそれらの使用 |
| JP2016159323A Withdrawn JP2016193942A (ja) | 2005-02-03 | 2016-08-15 | 抗コネキシン化合物およびそれらの使用 |
| JP2018077563A Pending JP2018111724A (ja) | 2005-02-03 | 2018-04-13 | 抗コネキシン化合物およびそれらの使用 |
| JP2019149110A Withdrawn JP2019194268A (ja) | 2005-02-03 | 2019-08-15 | 抗コネキシン化合物およびそれらの使用 |
Family Applications After (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012047133A Withdrawn JP2012107065A (ja) | 2005-02-03 | 2012-03-02 | 抗コネキシン化合物およびそれらの使用 |
| JP2014121150A Withdrawn JP2014169325A (ja) | 2005-02-03 | 2014-06-12 | 抗コネキシン化合物およびそれらの使用 |
| JP2016159323A Withdrawn JP2016193942A (ja) | 2005-02-03 | 2016-08-15 | 抗コネキシン化合物およびそれらの使用 |
| JP2018077563A Pending JP2018111724A (ja) | 2005-02-03 | 2018-04-13 | 抗コネキシン化合物およびそれらの使用 |
| JP2019149110A Withdrawn JP2019194268A (ja) | 2005-02-03 | 2019-08-15 | 抗コネキシン化合物およびそれらの使用 |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US9248141B2 (https=) |
| EP (5) | EP2510937A1 (https=) |
| JP (6) | JP5964538B2 (https=) |
| KR (4) | KR101840445B1 (https=) |
| CN (2) | CN101573131B (https=) |
| AU (2) | AU2006257283A1 (https=) |
| CA (1) | CA2596412A1 (https=) |
| DK (1) | DK1959981T3 (https=) |
| ES (1) | ES2766549T3 (https=) |
| HK (1) | HK1258903A1 (https=) |
| HU (1) | HUE047335T2 (https=) |
| WO (1) | WO2006134494A2 (https=) |
Families Citing this family (58)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9408381B2 (en) | 2004-12-21 | 2016-08-09 | Musc Foundation For Research Development | Alpha Connexin c-Terminal (ACT) peptides for use in transplant |
| SG158153A1 (en) | 2004-12-21 | 2010-01-29 | Musc Found For Res Dev | Compositions and methods for promoting wound healing and tissue regeneration |
| DK1959981T3 (da) | 2005-02-03 | 2020-01-27 | Coda Therapeutics Ltd | Anti-connexin 43 forbindelser til behandling af kroniske sår |
| EP2091557A2 (en) | 2006-11-15 | 2009-08-26 | Coda Therapeutics, INC. | Improved methods and compositions for wound healing |
| AU2014204482B2 (en) * | 2006-12-11 | 2016-07-07 | Coda Therapeutics, Inc. | Anticonnexin polynucleotides as impaired wound healing compositions |
| CN101835476B (zh) | 2006-12-11 | 2016-08-17 | 科达治疗公司 | 作为受损伤口愈合组合物的抗连接蛋白多核苷酸 |
| DK2166845T3 (en) * | 2007-06-21 | 2016-02-01 | Musc Found For Res Dev | ALFA-connexin C-terminal (ACT) peptides FOR THE TREATMENT OF AGE-related macular degeneration |
| NZ583803A (en) | 2007-09-07 | 2012-12-21 | Ind Res Ltd | Agents with angiogenic and wound healing activity |
| EP2245158A2 (en) * | 2007-12-11 | 2010-11-03 | Coda Therapeutics, Inc. | Impaired wound healing compositions and treatments |
| US20110300130A1 (en) * | 2007-12-11 | 2011-12-08 | Becker David L | Impaired wound healing compositions and treatments |
| US20110144182A1 (en) * | 2007-12-21 | 2011-06-16 | David Lawrence Becker | Treatment of surgical adhesions |
| JP2011507861A (ja) * | 2007-12-21 | 2011-03-10 | コーダ セラピューティクス, インコーポレイテッド | 線維症性の状態の治療のための抗コネキシンポリヌクレオチド剤と組み合わせた抗コネキシンポリペプチド剤の使用 |
| US8975237B2 (en) | 2007-12-21 | 2015-03-10 | Coda Therapeutics, Inc. | Treatment of fibrotic conditions |
| JP2011507599A (ja) | 2007-12-21 | 2011-03-10 | コーダ セラピューティクス, インコーポレイテッド | 改良医療デバイス |
| CA2710375A1 (en) * | 2007-12-21 | 2009-07-09 | Coda Therapeutics, Inc. | Treatment of orthopedic conditions |
| US20110243964A1 (en) * | 2007-12-21 | 2011-10-06 | Bradford James Duft | Treatment of orthopedic conditions |
| AU2008343839A1 (en) * | 2007-12-21 | 2009-07-09 | Coda Therapeutics, Inc. | Use of anti-connexin peptides, alone or in combination with anti-connexin polynucleotides, for the treatment of surgical adhesions |
| TW200950824A (en) | 2008-04-30 | 2009-12-16 | Kci Licensing Inc | Use of nucleic acids with reduced pressure therapy |
| WO2009148552A2 (en) * | 2008-06-02 | 2009-12-10 | Kansas State University Research Foundation | Methods and compositions for treating disease |
| US20110223204A1 (en) * | 2008-06-04 | 2011-09-15 | Bradford J Duft | Treatment of pain with gap junction modulation compounds |
| ITCH20080021A1 (it) * | 2008-09-25 | 2010-03-26 | Saverio Alberti | Usi in diagnosi e terapia dei tumori di un rna di fusione tra ciclina d1 e trop2 |
| WO2013073968A2 (en) * | 2011-09-12 | 2013-05-23 | Industrial Research Limited | Agents for modulation of cell signalling |
| CA2866115C (en) | 2012-03-01 | 2020-03-24 | Firststring Research, Inc. | Topical gels containing alpha connexin c-terminal (act) peptides |
| US9345744B2 (en) | 2012-04-25 | 2016-05-24 | Musc Foundation For Research Development | Peptide-based collagen modulators for wound healing and tissue repair |
| WO2013168642A1 (ja) | 2012-05-08 | 2013-11-14 | 石原産業株式会社 | 置換安息香酸化合物の製造方法 |
| WO2013179264A2 (en) | 2012-05-30 | 2013-12-05 | Universidad Andres Bello | Use of compounds that selectively modulate astrocytic release of substances through hemichannels of connexins and pannexins, without influencing gap junctions, for the treatment of psychiatric disorders |
| US9156896B2 (en) | 2013-03-15 | 2015-10-13 | Coda Therapeutics, Inc. | Wound healing compositions and treatments |
| CA2921652A1 (en) | 2013-08-21 | 2015-02-26 | Manuel A. Riquelme | Compositions and methods for targeting connexin hemichannels |
| WO2015191795A1 (en) * | 2014-06-12 | 2015-12-17 | The Research Foundation For The State University Of New York | Methods of using gap junctions as therapeutic targets for the treatment of degenerative disorders of the retina |
| US10465188B2 (en) | 2014-08-22 | 2019-11-05 | Auckland Uniservices Limited | Channel modulators |
| JP7185655B2 (ja) * | 2014-08-22 | 2022-12-07 | オークランド ユニサービシーズ リミティド | チャネル調節剤 |
| JP6898848B2 (ja) | 2014-09-19 | 2021-07-07 | メモリアル スローン ケタリング キャンサー センター | 脳転移を治療するための方法 |
| CN108024976A (zh) | 2015-07-15 | 2018-05-11 | 特兰埃克斯公司 | 阿米替林用于阻断大脑半通道的用途和用于增强其体内作用的方法 |
| EP3331545B1 (en) * | 2015-08-06 | 2021-03-10 | The Feinstein Institute for Medical Research | Hemichannel extracellular-domain specific agents for treating sepsis |
| CA3033909A1 (en) * | 2015-08-14 | 2017-02-23 | The University Of Sydney | Connexin 45 inhibition for therapy |
| CN105566495B (zh) * | 2016-01-27 | 2019-10-22 | 上海科技大学 | 一种特异性抑制连接蛋白26的全人抗体 |
| EP3419998A4 (en) | 2016-02-26 | 2019-09-25 | The Board of Regents of The University of Texas System | CONNEXIN (CX) 43 HEMICANAL BINDING ANTIBODIES AND USES THEREOF |
| US11433116B2 (en) * | 2016-04-14 | 2022-09-06 | Cedars-Sinai Medical Center | GJA1 isoforms protect against metabolic stress |
| CA3022763A1 (en) * | 2016-05-03 | 2017-11-09 | University Of Auckland | Novel peptides and peptidomimetics |
| US11136368B2 (en) | 2016-08-23 | 2021-10-05 | The Cleveland Clinic Foundation | Cancer treatment using CX26 blocking peptides |
| EP3521377A4 (en) | 2016-09-30 | 2019-10-02 | FUJIFILM Corporation | AQUEOUS SOLUTION, COLOR COMPOSITION, INK IRRIGATION INK INK, INK IRRIGATION METHOD AND INK CARTRIDGE |
| CN111201247A (zh) | 2017-04-28 | 2020-05-26 | 奥克兰联合服务有限公司 | 治疗方法和新颖构建体 |
| CA3070089A1 (en) | 2017-07-19 | 2019-01-24 | Auckland Uniservices Limited | Cytokine modulation |
| ES2976559T3 (es) * | 2017-09-20 | 2024-08-05 | Univ California | Terapia génica con conexina 43 para restaurar la función eléctrica y cardíaca y la estructura cardíaca, en la miocardiopatía arritmogénica del ventrículo derecho |
| US12098385B2 (en) | 2017-09-20 | 2024-09-24 | The Regents Of The University Of California | Gene therapy strategy to restore cardiac electrical and structural function in arrhythmogenic right ventricular cardiomyopathy |
| CN107469071B (zh) * | 2017-09-29 | 2021-01-26 | 河南大学 | Connexin模拟肽在制备预防或治疗急性肺损伤药物中的应用 |
| CN108066744A (zh) * | 2017-12-29 | 2018-05-25 | 于海龙 | 细胞连接蛋白43模拟肽Gap19在制备治疗脑出血药物中的用途 |
| US12227561B2 (en) | 2018-04-02 | 2025-02-18 | Alamab Therapeutics, Inc. | Connexin 43 antibodies and use thereof |
| CN108588075A (zh) * | 2018-05-03 | 2018-09-28 | 天德悦(北京)生物科技有限责任公司 | 人Cx43基因干扰序列、shRNA-Cx43病毒及低表达Cx43蛋白的细胞系 |
| WO2019222800A1 (en) * | 2018-05-21 | 2019-11-28 | Hudson Institute of Medical Research | Methods for the treatment or prevention of autoimmune or autoinflammatory diseases |
| IL285369B2 (en) * | 2019-02-04 | 2025-10-01 | Alamab Therapeutics Inc | Connexin 43 antibodies and their use |
| CN111484981B (zh) * | 2020-04-26 | 2021-02-02 | 四川省人民医院 | 一种用于构建视网膜新生血管疾病模型的方法和应用 |
| JP7036158B2 (ja) * | 2020-07-08 | 2022-03-15 | 株式会社リコー | 表示画像作成装置および画像表示装置 |
| JP2023537316A (ja) | 2020-07-31 | 2023-08-31 | アラマブ セラピューティクス, インコーポレイテッド | 抗コネキシン抗体製剤 |
| JP2023546757A (ja) | 2020-10-22 | 2023-11-07 | シークエル・バイオ・インコーポレイテッド | ペプチド製剤および眼科におけるその使用 |
| CN114859057A (zh) * | 2022-04-13 | 2022-08-05 | 江苏省中医院 | 人结直肠癌或人结直肠癌转移的预测性生物标志物及其应用 |
| US20240327488A1 (en) | 2023-03-28 | 2024-10-03 | Universidad Del Desarrollo | Connexin-46 peptide modulator |
| US20250059264A1 (en) * | 2023-08-14 | 2025-02-20 | Alamab Therapeutics, Inc. | Method of treating stroke |
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| US3687808A (en) | 1969-08-14 | 1972-08-29 | Univ Leland Stanford Junior | Synthetic polynucleotides |
| US5034506A (en) | 1985-03-15 | 1991-07-23 | Anti-Gene Development Group | Uncharged morpholino-based polymers having achiral intersubunit linkages |
| US4861757A (en) | 1986-11-14 | 1989-08-29 | Institute Of Molecular Biology | Wound healing and bone regeneration using PDGF and IGF-I |
| JPH0539594Y2 (https=) | 1988-08-05 | 1993-10-07 | ||
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| AU9016898A (en) | 1997-08-07 | 1999-03-01 | United States Of America, Represented By The Secretary, Department Of Health And Human Services, The | Methods and compositions for treatment of restenosis |
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| RU2420537C2 (ru) | 2001-01-17 | 2011-06-10 | Трабьон Фармасьютикалз Инк. | Слитые белки связывающий домен-иммуноглобулин |
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| PT1606318E (pt) * | 2003-03-26 | 2009-11-10 | Deutsches Krebsforsch | Proteínas de fusão de fc melhoradas |
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| CA3059497A1 (en) | 2003-12-03 | 2005-06-16 | Ocunexus Therapeutics, Inc. | Antisense compounds targeted to connexins and methods of use thereof |
| DE102004027422A1 (de) | 2004-06-04 | 2005-12-29 | Boehringer Ingelheim Microparts Gmbh | Vorrichtung zur Aufnahme von Blut und Abtrennung von Blutbestandteilen |
| SG158153A1 (en) * | 2004-12-21 | 2010-01-29 | Musc Found For Res Dev | Compositions and methods for promoting wound healing and tissue regeneration |
| DK1959981T3 (da) | 2005-02-03 | 2020-01-27 | Coda Therapeutics Ltd | Anti-connexin 43 forbindelser til behandling af kroniske sår |
| EA200870058A1 (ru) | 2005-12-16 | 2008-12-30 | Арла Фудс Амба | Композиции, содержащие остеопонтин крупного рогатого скота, для улучшения процесса заживления ран |
| EP2091557A2 (en) | 2006-11-15 | 2009-08-26 | Coda Therapeutics, INC. | Improved methods and compositions for wound healing |
| CN101835476B (zh) | 2006-12-11 | 2016-08-17 | 科达治疗公司 | 作为受损伤口愈合组合物的抗连接蛋白多核苷酸 |
| EP2114422A1 (en) | 2007-03-02 | 2009-11-11 | National University of Ireland, Galway | Osteopontin for the prediction and treatment of cardiovascular diseases |
| CN101765423B (zh) | 2007-05-31 | 2014-08-06 | 安特里奥公司 | 核酸纳米粒子和其用途 |
| EP2245158A2 (en) | 2007-12-11 | 2010-11-03 | Coda Therapeutics, Inc. | Impaired wound healing compositions and treatments |
| US20110300130A1 (en) | 2007-12-11 | 2011-12-08 | Becker David L | Impaired wound healing compositions and treatments |
| CA2710375A1 (en) | 2007-12-21 | 2009-07-09 | Coda Therapeutics, Inc. | Treatment of orthopedic conditions |
| CA2710232A1 (en) | 2007-12-21 | 2009-07-09 | Coda Therapeutics, Inc. | Treatment of abnormal or excessive scars |
| US20110144182A1 (en) | 2007-12-21 | 2011-06-16 | David Lawrence Becker | Treatment of surgical adhesions |
| US20110243964A1 (en) | 2007-12-21 | 2011-10-06 | Bradford James Duft | Treatment of orthopedic conditions |
| US8975237B2 (en) | 2007-12-21 | 2015-03-10 | Coda Therapeutics, Inc. | Treatment of fibrotic conditions |
| AU2008343758A1 (en) | 2007-12-21 | 2009-07-09 | Coda Therapeutics, Inc. | Use of anti-connexin 43 polynucleotides for the treatment of abnormal or excessive scars |
| AU2008343839A1 (en) | 2007-12-21 | 2009-07-09 | Coda Therapeutics, Inc. | Use of anti-connexin peptides, alone or in combination with anti-connexin polynucleotides, for the treatment of surgical adhesions |
| JP2011507599A (ja) | 2007-12-21 | 2011-03-10 | コーダ セラピューティクス, インコーポレイテッド | 改良医療デバイス |
| JP2011507861A (ja) | 2007-12-21 | 2011-03-10 | コーダ セラピューティクス, インコーポレイテッド | 線維症性の状態の治療のための抗コネキシンポリヌクレオチド剤と組み合わせた抗コネキシンポリペプチド剤の使用 |
| US20110038920A1 (en) | 2008-01-07 | 2011-02-17 | Ryoichi Mori | Wound healing compositions and treatments |
| US20110223204A1 (en) | 2008-06-04 | 2011-09-15 | Bradford J Duft | Treatment of pain with gap junction modulation compounds |
-
2006
- 2006-02-03 DK DK06795121.0T patent/DK1959981T3/da active
- 2006-02-03 WO PCT/IB2006/001961 patent/WO2006134494A2/en not_active Ceased
- 2006-02-03 EP EP12172476A patent/EP2510937A1/en not_active Withdrawn
- 2006-02-03 AU AU2006257283A patent/AU2006257283A1/en not_active Abandoned
- 2006-02-03 ES ES06795121T patent/ES2766549T3/es not_active Expired - Lifetime
- 2006-02-03 KR KR1020167013933A patent/KR101840445B1/ko not_active Expired - Fee Related
- 2006-02-03 EP EP12172477A patent/EP2510938A1/en not_active Withdrawn
- 2006-02-03 KR KR1020077020138A patent/KR20080031154A/ko not_active Ceased
- 2006-02-03 KR KR1020147033485A patent/KR20150004906A/ko not_active Ceased
- 2006-02-03 EP EP06795121.0A patent/EP1959981B1/en not_active Expired - Lifetime
- 2006-02-03 KR KR1020187007409A patent/KR102073629B1/ko not_active Expired - Fee Related
- 2006-02-03 CA CA002596412A patent/CA2596412A1/en not_active Abandoned
- 2006-02-03 CN CN200680010590.XA patent/CN101573131B/zh not_active Expired - Fee Related
- 2006-02-03 CN CN201711202710.2A patent/CN108324923A/zh active Pending
- 2006-02-03 EP EP12172475.1A patent/EP2662088A3/en not_active Withdrawn
- 2006-02-03 JP JP2007553747A patent/JP5964538B2/ja not_active Expired - Fee Related
- 2006-02-03 EP EP12172478A patent/EP2510939A1/en not_active Withdrawn
- 2006-02-03 HU HUE06795121A patent/HUE047335T2/hu unknown
- 2006-02-03 US US11/883,739 patent/US9248141B2/en not_active Expired - Fee Related
-
2011
- 2011-03-02 AU AU2011200924A patent/AU2011200924A1/en not_active Abandoned
-
2012
- 2012-03-02 JP JP2012047133A patent/JP2012107065A/ja not_active Withdrawn
-
2014
- 2014-06-12 JP JP2014121150A patent/JP2014169325A/ja not_active Withdrawn
-
2016
- 2016-02-01 US US15/012,732 patent/US10201590B2/en not_active Expired - Fee Related
- 2016-08-15 JP JP2016159323A patent/JP2016193942A/ja not_active Withdrawn
-
2018
- 2018-04-13 JP JP2018077563A patent/JP2018111724A/ja active Pending
-
2019
- 2019-01-25 HK HK19101379.8A patent/HK1258903A1/zh unknown
- 2019-08-15 JP JP2019149110A patent/JP2019194268A/ja not_active Withdrawn
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