JP2008508859A5 - - Google Patents

Download PDF

Info

Publication number
JP2008508859A5
JP2008508859A5 JP2007513935A JP2007513935A JP2008508859A5 JP 2008508859 A5 JP2008508859 A5 JP 2008508859A5 JP 2007513935 A JP2007513935 A JP 2007513935A JP 2007513935 A JP2007513935 A JP 2007513935A JP 2008508859 A5 JP2008508859 A5 JP 2008508859A5
Authority
JP
Japan
Prior art keywords
binding molecule
seq
pharmaceutical composition
rabies virus
chain variable
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2007513935A
Other languages
English (en)
Japanese (ja)
Other versions
JP4768730B2 (ja
JP2008508859A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/EP2005/052410 external-priority patent/WO2005118644A2/en
Publication of JP2008508859A publication Critical patent/JP2008508859A/ja
Publication of JP2008508859A5 publication Critical patent/JP2008508859A5/ja
Application granted granted Critical
Publication of JP4768730B2 publication Critical patent/JP4768730B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

JP2007513935A 2004-05-27 2005-05-26 狂犬病ウイルスを中和することができる結合分子およびそれらの用途 Expired - Fee Related JP4768730B2 (ja)

Applications Claiming Priority (15)

Application Number Priority Date Filing Date Title
US57502304P 2004-05-27 2004-05-27
EPPCT/EP2004/050943 2004-05-27
US60/575,023 2004-05-27
EP2004050943 2004-05-27
EP2004051661 2004-07-29
EPPCT/EP2004/051661 2004-07-29
EP2004052286 2004-09-23
EPPCT/EP2004/052286 2004-09-23
EP2004052772 2004-11-03
EPPCT/EP2004/052772 2004-11-03
EPPCT/EP2005/050310 2005-01-25
EP2005050310 2005-01-25
EP2005050953 2005-03-03
EPPCT/EP2005/050953 2005-03-03
PCT/EP2005/052410 WO2005118644A2 (en) 2004-05-27 2005-05-26 Binding molecules capable of neutralizing rabies virus and uses thereof

Publications (3)

Publication Number Publication Date
JP2008508859A JP2008508859A (ja) 2008-03-27
JP2008508859A5 true JP2008508859A5 (OSRAM) 2008-07-10
JP4768730B2 JP4768730B2 (ja) 2011-09-07

Family

ID=34968690

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2007513935A Expired - Fee Related JP4768730B2 (ja) 2004-05-27 2005-05-26 狂犬病ウイルスを中和することができる結合分子およびそれらの用途

Country Status (22)

Country Link
US (5) US7579446B2 (OSRAM)
EP (3) EP2314621B1 (OSRAM)
JP (1) JP4768730B2 (OSRAM)
KR (2) KR101228157B1 (OSRAM)
CN (5) CN102139106B (OSRAM)
AT (1) ATE501171T1 (OSRAM)
AU (1) AU2005250163B2 (OSRAM)
BR (1) BRPI0511479C1 (OSRAM)
CA (1) CA2568162C (OSRAM)
CU (1) CU23719A3 (OSRAM)
CY (1) CY1111550T1 (OSRAM)
DK (1) DK1749029T3 (OSRAM)
EA (1) EA010785B1 (OSRAM)
ES (2) ES2426725T3 (OSRAM)
HR (3) HRP20110320T1 (OSRAM)
IL (3) IL179586A (OSRAM)
MX (1) MXPA06013482A (OSRAM)
NZ (2) NZ550366A (OSRAM)
PL (3) PL2314621T3 (OSRAM)
PT (3) PT2314620E (OSRAM)
RS (2) RS51847B (OSRAM)
WO (1) WO2005118644A2 (OSRAM)

Families Citing this family (52)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7658924B2 (en) 2001-10-11 2010-02-09 Amgen Inc. Angiopoietin-2 specific binding agents
WO2003106498A2 (en) * 2002-06-13 2003-12-24 Crucell Holland, B.V. Agonistic binding molecules to the human ox40 receptor
EP1539235A2 (en) 2002-07-01 2005-06-15 Human Genome Sciences, Inc. Antibodies that specifically bind to reg iv
CN105884893A (zh) 2002-07-18 2016-08-24 莫鲁斯有限公司 抗体混合物的重组生产
USRE47770E1 (en) 2002-07-18 2019-12-17 Merus N.V. Recombinant production of mixtures of antibodies
US20100069614A1 (en) 2008-06-27 2010-03-18 Merus B.V. Antibody producing non-human mammals
WO2004106375A1 (en) 2003-05-30 2004-12-09 Merus Biopharmaceuticals B.V. I.O. Fab library for the preparation of anti vegf and anti rabies virus fabs
EP1636265A2 (en) 2003-06-25 2006-03-22 Crucell Holland B.V. Binding molecules for the treatment of myeloid cell malignancies
CA2531684C (en) * 2003-07-22 2014-03-11 Crucell Holland B.V. Binding molecules against sars-coronavirus and uses thereof
CN102139106B (zh) 2004-05-27 2014-10-08 克鲁塞尔荷兰公司 能中和狂犬病病毒的结合分子及其应用
EP1799259B1 (en) * 2004-10-12 2012-12-05 Crucell Holland B.V. Binding molecules for the detection of cancer
US8052974B2 (en) 2005-05-12 2011-11-08 Crucell Holland B.V. Host cell specific binding molecules capable of neutralizing viruses and uses thereof
WO2007031550A2 (en) * 2005-09-15 2007-03-22 Crucell Holland B.V. Method for preparing immunoglobulin libraries
WO2007038407A2 (en) 2005-09-23 2007-04-05 The Regents Of The University Of California Compositions and methods for treating nervous system disorders
JP5574706B2 (ja) 2006-06-06 2014-08-20 クルセル ホランド ベー ヴェー ブドウ球菌に対する殺活性を有するヒトの結合分子及びその使用方法
KR20200058579A (ko) 2006-06-06 2020-05-27 얀센 백신스 앤드 프리벤션 비.브이. 장내구균에 대한 사멸활성을 갖는 인간결합분자 및 그것의 용도
EA017203B1 (ru) 2006-09-07 2012-10-30 Круселл Холланд Б.В. Связывающие молекулы человека, способные нейтрализовать вирус гриппа h5n1, и их применение
US7959922B2 (en) * 2006-12-05 2011-06-14 Crucell Holland B.V. Liquid anti-rabies antibody formulations
WO2009000099A2 (en) 2007-06-25 2008-12-31 Esbatech Ag Methods of modifying antibodies, and modified antibodies with improved functional properties
JO2913B1 (en) 2008-02-20 2015-09-15 امجين إنك, Antibodies directed towards angiopoietin-1 and angiopoietin-2 proteins and their uses
WO2010132532A1 (en) 2009-05-15 2010-11-18 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services B cell surface reactive antibodies
WO2011028961A2 (en) 2009-09-04 2011-03-10 Xoma Technology Ltd. Anti-botulism antibody coformulations
MX2012003811A (es) * 2009-10-02 2012-05-08 Univ California Anticuerpos monoclonales.
CN101696242B (zh) * 2009-10-26 2011-12-28 中国人民解放军南京军区军事医学研究所 人源抗狂犬病毒中和抗体Fab及其制备方法和应用
CN103596975A (zh) * 2010-01-04 2014-02-19 印度免疫有限公司 针对狂犬病病毒的重组人二价双链抗体及其用途
WO2011102517A1 (ja) * 2010-02-19 2011-08-25 独立行政法人科学技術振興機構 抗ウイルス剤、抗体酵素、プライマーセット、ポリヌクレオチドの製造方法、および、ポリペプチドの製造方法
AU2011223710B2 (en) 2010-03-01 2016-04-14 Bayer Healthcare Llc Optimized monoclonal antibodies against tissue factor pathway inhibitor (TFPI)
KR101814571B1 (ko) 2010-03-10 2018-01-04 젠맵 에이/에스 Ｃ―ｍｅｔ에 대한 모노클로날 항체
EP2582727B8 (en) * 2010-06-16 2017-04-19 University of Pittsburgh- Of the Commonwealth System of Higher Education Antibodies to endoplasmin and their use
KR101388680B1 (ko) * 2011-03-18 2014-04-28 (주)셀트리온 광견병 바이러스를 중화시킬 수 있는 결합 분자
CA2791109C (en) 2011-09-26 2021-02-16 Merus B.V. Generation of binding molecules
KR101495019B1 (ko) 2011-09-30 2015-02-24 (주)셀트리온 광견병 바이러스를 중화시킬 수 있는 결합 분자
PT2838917T (pt) 2012-04-20 2019-09-12 Merus Nv Métodos e meios para a produção de moléculas similares a ig heterodiméricas
CN102924571A (zh) * 2012-10-29 2013-02-13 复旦大学 狂犬病毒糖蛋白与核蛋白的抗原表位多肽及其筛选、鉴定方法与应用
KR101739313B1 (ko) * 2013-12-12 2017-05-24 (주)셀트리온 광견병 바이러스를 중화시킬 수 있는 결합 분자
CN103954777A (zh) * 2014-05-20 2014-07-30 北京凯思百奥科技发展有限公司 一种狂犬病病毒单克隆抗体及其应用
RU2549971C1 (ru) * 2014-07-01 2015-05-10 Федеральное казённое учреждение здравоохранения Ставропольский научно-исследовательский противочумный институт Федеральной службы по надзору в сфере защиты прав потребителей и благополучия человека Способ консервации иммунопероксидазного конъюгата
CN104761640A (zh) * 2015-02-03 2015-07-08 中国食品药品检定研究院 具有中和活性的抗狂犬病病毒单克隆抗体的制备及应用
JP6917902B2 (ja) * 2015-02-13 2021-08-11 ソレント・セラピューティクス・インコーポレイテッド Ｃｔｌａ４に結合する抗体医薬
WO2016200189A1 (ko) * 2015-06-10 2016-12-15 (주)셀트리온 광견병 바이러스 g 단백질의 에피토프 및 이에 특이적으로 결합하는 광견병 바이러스 중화 결합 분자
US11505599B2 (en) 2016-01-14 2022-11-22 Memorial Sloan-Kettering Cancer Center T cell receptor-like antibodies specific for Foxp3-derived peptides
JOP20190248A1 (ar) 2017-04-21 2019-10-20 Amgen Inc بروتينات ربط مولد ضد trem2 واستخداماته
RU2718835C2 (ru) * 2017-12-29 2020-04-15 Федеральное государственное бюджетное образовательное учреждение высшего образования "Московский государственный университет имени М.В. Ломоносова" (МГУ) Нейтрализующее моноклональное антитело, связывающееся с гликопротеином g вируса бешенства, фрагменты днк, кодирующие указанное антитело, и антигенсвязывающий фрагмент
WO2019227039A1 (en) * 2018-05-24 2019-11-28 Lankenau Institute For Medical Research Compositions comprising antibodies to rabies virus and the uses thereof
CN110317267B (zh) * 2018-08-09 2020-11-20 北京智仁美博生物科技有限公司 针对狂犬病病毒的双特异性抗体及其用途
AU2020281380B2 (en) * 2019-05-30 2024-04-11 Shandong Boan Biotechnology Co., Ltd. Antibody or chimeric antigen receptor which targets claudin 18.2
CN111171145B (zh) * 2020-01-21 2021-11-05 兰州生物制品研究所有限责任公司 一种抗狂犬病病毒单克隆抗体、制备方法及用途
US20240043504A1 (en) * 2020-05-26 2024-02-08 Regeneron Pharmaceuticals, Inc. Anti-SARS-CoV-2-Spike Glycoprotein Antibodies and Antigen-Binding Fragments
US20250084163A1 (en) * 2021-04-09 2025-03-13 Sorrento Therapeutics, Inc. Antigen Binding Proteins That Bind ROR1
CN114397453B (zh) * 2022-03-25 2022-06-07 江苏美克医学技术有限公司 新型冠状病毒突变株的检测试剂盒及其应用
CN119930826A (zh) * 2023-11-02 2025-05-06 重庆精准生物产业技术研究院有限公司 针对psca的全人源单链抗体及其应用
CN117777282B (zh) * 2023-12-07 2025-03-04 兰州生物制品研究所有限责任公司 一种抗狂犬病病毒中和抗体及其制备和应用

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ207394A (en) 1983-03-08 1987-03-06 Commw Serum Lab Commission Detecting or determining sequence of amino acids
EP0402029B1 (en) * 1989-06-08 1994-01-12 The Wistar Institute Monoclonal antibodies for post exposure treatment of rabies
DE4006630A1 (de) * 1990-03-03 1991-09-12 Behringwerke Ag Humane monoklonale antikoerper gegen tollwutviren, ihre herstellung und verwendung
NL9101953A (nl) 1991-11-21 1993-06-16 Seed Capital Investments Testinrichting omvattende een plaat met een veelvoud van putjes met een bijbehorende doseerinrichting, alsmede een kit die deze inrichtingen omvat en toepassing van de inrichtingen.
US5624949A (en) 1993-12-07 1997-04-29 Eli Lilly And Company Protein kinase C inhibitors
US6265150B1 (en) 1995-06-07 2001-07-24 Becton Dickinson & Company Phage antibodies
ATE230850T1 (de) 1996-10-08 2003-01-15 Bisys B V U Verfahren und mittel zur auswahl von peptiden und proteinen mit spezifischer affinität zu einem zielmolekül
CA2370477C (en) 1999-04-15 2010-06-29 Crucell Holland B.V. Recombinant protein production in a human cell using sequences encoding adenovirus e1 protein
US7071319B2 (en) * 2000-05-16 2006-07-04 Thomas Jefferson University Recombinant antibodies, and compositions and methods for making and using the same
US20040013672A1 (en) * 2000-05-16 2004-01-22 Thomas Jefferson University Recombinant antibodies, and compositions and methods for making and using the same
CA2449071C (en) 2001-06-15 2008-12-16 Crucell Holland B.V. Chimaeric phages
AU2002332600B2 (en) * 2001-08-21 2007-03-22 Thomas Jefferson University Recombinant antibodies, and compositions and methods for making and using the same
WO2003106498A2 (en) 2002-06-13 2003-12-24 Crucell Holland, B.V. Agonistic binding molecules to the human ox40 receptor
CN105884893A (zh) * 2002-07-18 2016-08-24 莫鲁斯有限公司 抗体混合物的重组生产
US20100069614A1 (en) * 2008-06-27 2010-03-18 Merus B.V. Antibody producing non-human mammals
EP1636265A2 (en) 2003-06-25 2006-03-22 Crucell Holland B.V. Binding molecules for the treatment of myeloid cell malignancies
CA2531684C (en) * 2003-07-22 2014-03-11 Crucell Holland B.V. Binding molecules against sars-coronavirus and uses thereof
ATE516305T1 (de) 2004-02-27 2011-07-15 Inst Nat Sante Rech Med Il-15-bindungsstelle für il-15-ralpha und spezifische il-15-mutanten mit wirkung als agonisten/antagonisten
CN102139106B (zh) * 2004-05-27 2014-10-08 克鲁塞尔荷兰公司 能中和狂犬病病毒的结合分子及其应用
NZ553701A (en) 2004-11-11 2009-12-24 Crucell Holland Bv Composition comprising SC03-014 and SC03-022 antibodies against SARS-CoV
CA2591665C (en) 2004-12-20 2015-05-05 Crucell Holland B.V. Binding molecules capable of neutralizing west nile virus and uses thereof
KR101280273B1 (ko) 2005-04-18 2013-07-15 예다 리서치 앤드 디벨럽먼트 캄파니 리미티드 안정화된 항-ｂ형 간염 바이러스 (ｈｂｖ) 항체 제형
US8052974B2 (en) 2005-05-12 2011-11-08 Crucell Holland B.V. Host cell specific binding molecules capable of neutralizing viruses and uses thereof
US20090130652A1 (en) 2005-06-23 2009-05-21 Crucell Holland B.V. Optimization of West Nile Virus Antibodies
TWI389904B (zh) * 2006-02-27 2013-03-21 Elan Pharm Inc 抑制由ｖｌａ-４所調節的白血球黏附之嘧啶磺醯胺化合物
JP5574706B2 (ja) * 2006-06-06 2014-08-20 クルセル ホランド ベー ヴェー ブドウ球菌に対する殺活性を有するヒトの結合分子及びその使用方法
KR20200058579A (ko) * 2006-06-06 2020-05-27 얀센 백신스 앤드 프리벤션 비.브이. 장내구균에 대한 사멸활성을 갖는 인간결합분자 및 그것의 용도
EA017203B1 (ru) * 2006-09-07 2012-10-30 Круселл Холланд Б.В. Связывающие молекулы человека, способные нейтрализовать вирус гриппа h5n1, и их применение
US7959922B2 (en) 2006-12-05 2011-06-14 Crucell Holland B.V. Liquid anti-rabies antibody formulations

Similar Documents

Publication Publication Date Title
JP2008508859A5 (OSRAM)
JP2010502207A5 (OSRAM)
WO2008079372A3 (en) Novel immunogenic compositions for the prevention and treatment of meningococcal disease
JP2006526414A5 (OSRAM)
JP2005511076A5 (OSRAM)
JP2008529558A5 (OSRAM)
JP2019511222A5 (OSRAM)
JP2011250797A5 (OSRAM)
JP2005503789A5 (OSRAM)
WO2011020783A3 (en) Targeted immunoconjugates
JP2010516290A5 (OSRAM)
WO2003063766A3 (en) Novel immunogenic compositions for the prevention and treatment of meningococcal disease
NZ595387A (en) Peptides for treatment and diagnosis of autoimmune disease
RU2007139915A (ru) Haemophilus influenzae типа в
JP2010166916A5 (OSRAM)
MXPA05011110A (es) Composiciones inmunogenicas novedosas para la prevencion y tratamiento de un padecimiento originado por meningococos.
ATE535252T1 (de) Peptid-konjugat-zusammensetzungen und -verfahren zur prävention und behandlung von alzheimer- krankheit
HRP20110320T1 (hr) Molekule za vezanje koje mogu neutralizirati virus bjesnoće i njihova uporaba
JP2008538183A5 (OSRAM)
WO2010044889A3 (en) Torque teno virus (ttv) isolates and compositions
IL187321A (en) Molecules that have a specific link to a surrogate cell that encode monoclonal antibodies capable of neutralizing viruses, medicinal preparations containing them, and their uses in drug preparation
JP2008536483A5 (OSRAM)
JP2008525033A5 (OSRAM)
JP2009520758A5 (OSRAM)
WO2009079481A3 (en) Methods to diagnose and immunize against the virus causing human merkel cell carcinoma