JP2008044952A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2008044952A5 JP2008044952A5 JP2007241012A JP2007241012A JP2008044952A5 JP 2008044952 A5 JP2008044952 A5 JP 2008044952A5 JP 2007241012 A JP2007241012 A JP 2007241012A JP 2007241012 A JP2007241012 A JP 2007241012A JP 2008044952 A5 JP2008044952 A5 JP 2008044952A5
- Authority
- JP
- Japan
- Prior art keywords
- group
- mono
- substituted
- halogen atom
- lower alkoxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 125000003545 alkoxy group Chemical group 0.000 claims 6
- 125000000217 alkyl group Chemical group 0.000 claims 6
- 125000003277 amino group Chemical group 0.000 claims 4
- 125000005843 halogen group Chemical group 0.000 claims 4
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 4
- 125000004453 alkoxycarbonyl group Chemical group 0.000 claims 3
- 125000004390 alkyl sulfonyl group Chemical group 0.000 claims 3
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 claims 3
- 125000005236 alkanoylamino group Chemical group 0.000 claims 2
- 125000005153 alkyl sulfamoyl group Chemical group 0.000 claims 2
- 125000004644 alkyl sulfinyl group Chemical group 0.000 claims 2
- 125000004414 alkyl thio group Chemical group 0.000 claims 2
- 125000004397 aminosulfonyl group Chemical group NS(=O)(=O)* 0.000 claims 2
- 125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 claims 2
- 125000004093 cyano group Chemical group *C#N 0.000 claims 2
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 claims 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims 2
- 150000003839 salts Chemical class 0.000 claims 2
- 125000003282 alkyl amino group Chemical group 0.000 claims 1
- 125000003118 aryl group Chemical group 0.000 claims 1
- 125000002057 carboxymethyl group Chemical group [H]OC(=O)C([H])([H])[*] 0.000 claims 1
- 125000002485 formyl group Chemical group [H]C(*)=O 0.000 claims 1
- 125000000623 heterocyclic group Chemical group 0.000 claims 1
- -1 nitrogen-containing 5-membered heterocyclic compound Chemical class 0.000 claims 1
- 229910052760 oxygen Inorganic materials 0.000 claims 1
- 229910052717 sulfur Inorganic materials 0.000 claims 1
- 125000001544 thienyl group Chemical group 0.000 claims 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2007241012A JP2008044952A (ja) | 2001-04-16 | 2007-09-18 | 高コンダクタンス型カルシウム感受性kチャネル開口薬 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2001116436 | 2001-04-16 | ||
| JP2001249671 | 2001-08-20 | ||
| JP2007241012A JP2008044952A (ja) | 2001-04-16 | 2007-09-18 | 高コンダクタンス型カルシウム感受性kチャネル開口薬 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002580915A Division JP4073786B2 (ja) | 2001-04-16 | 2002-04-15 | 高コンダクタンス型カルシウム感受性kチャネル開口薬 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008044952A JP2008044952A (ja) | 2008-02-28 |
| JP2008044952A5 true JP2008044952A5 (enExample) | 2008-06-26 |
Family
ID=26613619
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002580915A Expired - Fee Related JP4073786B2 (ja) | 2001-04-16 | 2002-04-15 | 高コンダクタンス型カルシウム感受性kチャネル開口薬 |
| JP2007241012A Pending JP2008044952A (ja) | 2001-04-16 | 2007-09-18 | 高コンダクタンス型カルシウム感受性kチャネル開口薬 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002580915A Expired - Fee Related JP4073786B2 (ja) | 2001-04-16 | 2002-04-15 | 高コンダクタンス型カルシウム感受性kチャネル開口薬 |
Country Status (17)
| Country | Link |
|---|---|
| US (2) | US7759373B2 (enExample) |
| EP (1) | EP1432690A2 (enExample) |
| JP (2) | JP4073786B2 (enExample) |
| KR (1) | KR100863659B1 (enExample) |
| CN (2) | CN101519386A (enExample) |
| AR (1) | AR035828A1 (enExample) |
| AU (1) | AU2002246397B2 (enExample) |
| BR (1) | BR0208956A (enExample) |
| CA (1) | CA2444596A1 (enExample) |
| CZ (1) | CZ20032829A3 (enExample) |
| HU (1) | HUP0303829A3 (enExample) |
| IL (1) | IL158168A0 (enExample) |
| MX (1) | MXPA03009440A (enExample) |
| NZ (1) | NZ529043A (enExample) |
| PL (1) | PL367325A1 (enExample) |
| TW (2) | TW201006831A (enExample) |
| WO (1) | WO2002083111A2 (enExample) |
Families Citing this family (94)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4484439B2 (ja) * | 2002-03-14 | 2010-06-16 | 国立大学法人東京工業大学 | Vdac調節剤 |
| JP4570955B2 (ja) * | 2002-07-09 | 2010-10-27 | バーテクス ファーマスーティカルズ インコーポレイテッド | プロテインキナーゼ阻害活性を持つイミダゾール類 |
| ES2497116T3 (es) | 2002-08-19 | 2014-09-22 | Lorus Therapeutics Inc. | Imidazoles 2,4,5-trisustituidos y su uso como agentes antimicrobianos |
| TWI271402B (en) | 2002-10-15 | 2007-01-21 | Tanabe Seiyaku Co | Large conductance calcium-activated K channel opener |
| GB0315950D0 (en) * | 2003-06-11 | 2003-08-13 | Xention Discovery Ltd | Compounds |
| WO2005047266A1 (en) | 2003-11-14 | 2005-05-26 | Lorus Therapeutics Inc. | Aryl imidazoles and their use as anti-cancer agents |
| MXPA06005989A (es) | 2003-12-19 | 2006-08-23 | Basf Ag | Fenilalanina-amidas sustituidas por benzoilo. |
| TWI332003B (en) | 2004-01-30 | 2010-10-21 | Lilly Co Eli | Kinase inhibitors |
| US7179827B2 (en) | 2004-03-31 | 2007-02-20 | Lexicon Genetics Incorporated | Thiazoles and methods of their use |
| JP2005325103A (ja) * | 2004-04-13 | 2005-11-24 | Tanabe Seiyaku Co Ltd | 医薬組成物 |
| BRPI0511916B1 (pt) | 2004-06-10 | 2014-10-14 | Shikoku Chem | Fenilnaftilimidazóis para uso em superfícies de cobre durante soldagem |
| WO2005121132A1 (ja) * | 2004-06-11 | 2005-12-22 | Shionogi & Co., Ltd. | 抗hcv作用を有する縮合ヘテロ環化合物 |
| TW200616969A (en) * | 2004-09-17 | 2006-06-01 | Tanabe Seiyaku Co | Imidazole compound |
| CN101228133A (zh) | 2005-05-25 | 2008-07-23 | 巴斯福股份公司 | 杂芳酰基取代的丝氨酸酰胺 |
| EP1915374B1 (en) * | 2005-05-25 | 2014-04-02 | Lorus Therapeutics Inc. | 2-indolyl imidazo[4,5-d]phenanthroline derivatives and their use in the treatment of cancer |
| JPWO2006137527A1 (ja) | 2005-06-23 | 2009-01-22 | 協和発酵キリン株式会社 | チアゾール誘導体 |
| TWI387592B (zh) | 2005-08-30 | 2013-03-01 | Novartis Ag | 經取代之苯并咪唑及其作為與腫瘤形成相關激酶之抑制劑之方法 |
| AR056720A1 (es) * | 2005-10-26 | 2007-10-17 | Smithkline Beecham Corp | Compuesto de tiazol substtuido composicion farmaceuticamente que lo comprende y su uso para preparar un medicamento |
| JP5328640B2 (ja) | 2006-04-19 | 2013-10-30 | ノバルティス アーゲー | 6−o−置換ベンゾオキサゾールおよびベンゾチアゾール化合物ならびにcsf−1rシグナル伝達を阻害する方法 |
| WO2009125870A1 (en) | 2008-04-09 | 2009-10-15 | Mitsubishi Tanabe Pharma Corporation | Pyrimidine, pyridine and triazine derivatives as maxi-k channel openers. |
| UA103319C2 (en) | 2008-05-06 | 2013-10-10 | Глаксосмитклайн Ллк | Thiazole- and oxazole-benzene sulfonamide compounds |
| ES2526966T3 (es) | 2008-06-05 | 2015-01-19 | Glaxo Group Limited | Compuestos novedosos |
| ATE552255T1 (de) | 2008-06-05 | 2012-04-15 | Glaxo Group Ltd | 4-aminoindazole |
| ES2445199T3 (es) | 2008-06-05 | 2014-02-28 | Glaxo Group Limited | Derivados de benzpirazol como inhibidores de PI3-quinasas |
| EP3725775A1 (en) * | 2009-02-17 | 2020-10-21 | Syntrix Biosystems, Inc. | Pyridine- and pyrimidinecarboxamides as cxcr2 modulators |
| WO2010102958A1 (en) | 2009-03-09 | 2010-09-16 | Glaxo Group Limited | 4-oxadiazol-2 -yl- indazoles as inhibitors of p13 kinases |
| CA2759476C (en) | 2009-04-30 | 2018-10-09 | Julie Nicole Hamblin | Novel compounds |
| US8779149B2 (en) | 2010-08-23 | 2014-07-15 | Syntrix Biosystems, Inc. | Aminopyridine- and aminopyrimidinecarboxamides as CXCR2 modulators |
| EP2630682A4 (en) | 2010-10-22 | 2014-10-01 | Commw Scient Ind Res Org | ORGANIC ELECTROLUMINESCENCE ELEMENT |
| GB201018124D0 (en) | 2010-10-27 | 2010-12-08 | Glaxo Group Ltd | Polymorphs and salts |
| MX355782B (es) | 2010-11-03 | 2018-04-30 | Dow Agrosciences Llc | Composiciones pesticidas y procesos relacionados a las mismas. |
| EP2655362A1 (en) | 2010-12-22 | 2013-10-30 | Abbvie Inc. | Hepatitis c inhibitors and uses thereof |
| WO2012099785A2 (en) * | 2011-01-20 | 2012-07-26 | The Regents Of The University Of Colorado, A Body Corporate | Modulators of tlr3/dsrna complex and uses thereof |
| CN104010505B (zh) | 2011-10-26 | 2017-03-15 | 陶氏益农公司 | 杀虫组合物和与其相关的方法 |
| US9708288B2 (en) | 2012-04-27 | 2017-07-18 | Dow Agrosciences Llc | Pesticidal compositions and processes related thereto |
| US9282739B2 (en) | 2012-04-27 | 2016-03-15 | Dow Agrosciences Llc | Pesticidal compositions and processes related thereto |
| BR122014028247A2 (pt) | 2012-04-27 | 2019-05-07 | Dow Agrosciences Llc | composições pesticidas, processo para controlar praga, uso de uma molécula, processo para aumentar a saúde, rendimento, vigor, qualidade ou tolerância de uma planta e processos para produção de compostos |
| BR112015001769A2 (pt) * | 2012-07-27 | 2017-08-22 | Bial Portela & Ca Sa | Processo para a síntese de compostos de ureia substituída |
| JP5858884B2 (ja) * | 2012-08-16 | 2016-02-10 | 四国化成工業株式会社 | チオフェン環を有するイミダゾール化合物 |
| JP5892605B2 (ja) * | 2012-08-17 | 2016-03-23 | 四国化成工業株式会社 | 4−(2−チエニル)イミダゾール化合物 |
| JP5885620B2 (ja) * | 2012-08-22 | 2016-03-15 | 四国化成工業株式会社 | 2−(2−フリル)イミダゾール化合物及び酸化防止剤 |
| RU2632192C2 (ru) * | 2013-03-08 | 2017-10-03 | Вокхардт Лимитед | Способ получения натриевой соли (2s,5r)-2-карбоксамидо-7-оксо-6-сульфоокси-1,6-диазабицикло[3.2.1]октана |
| EP2976342A4 (en) | 2013-03-20 | 2016-08-10 | Aptose Biosciences Inc | 2-SUBSTITUTED IMIDAZO [4,5-D] PHENANTHROLINE DERIVATIVES AND THEIR USE IN THE TREATMENT OF CANCER |
| US10046002B2 (en) | 2013-08-02 | 2018-08-14 | Syntrix Biosystems Inc. | Method for treating cancer using chemokine antagonists |
| US8969365B2 (en) | 2013-08-02 | 2015-03-03 | Syntrix Biosystems, Inc. | Thiopyrimidinecarboxamides as CXCR1/2 modulators |
| US10561676B2 (en) | 2013-08-02 | 2020-02-18 | Syntrix Biosystems Inc. | Method for treating cancer using dual antagonists of CXCR1 and CXCR2 |
| US20150104392A1 (en) | 2013-10-04 | 2015-04-16 | Aptose Biosciences Inc. | Compositions, biomarkers and their use in the treatment of cancer |
| US9102655B2 (en) | 2013-10-17 | 2015-08-11 | Dow Agrosciences Llc | Processes for the preparation of pesticidal compounds |
| EP3057430A4 (en) | 2013-10-17 | 2017-09-13 | Dow AgroSciences LLC | Processes for the preparation of pesticidal compounds |
| BR112016007518A2 (pt) | 2013-10-17 | 2017-08-01 | Dow Agrosciences Llc | processos para a preparação de compostos pesticidas |
| JP2016536295A (ja) | 2013-10-17 | 2016-11-24 | ダウ アグロサイエンシィズ エルエルシー | 有害生物防除性化合物の製造方法 |
| KR20160072155A (ko) | 2013-10-17 | 2016-06-22 | 다우 아그로사이언시즈 엘엘씨 | 살충성 화합물의 제조 방법 |
| MX2016004941A (es) | 2013-10-17 | 2016-06-28 | Dow Agrosciences Llc | Proceso para la preparacion de compuestos plaguicidas. |
| MX2016004946A (es) | 2013-10-17 | 2016-06-28 | Dow Agrosciences Llc | Procesos para la preparacion de compuestos plaguicidas. |
| CN105828611A (zh) | 2013-10-22 | 2016-08-03 | 美国陶氏益农公司 | 协同杀虫组合物和相关方法 |
| WO2015061145A1 (en) | 2013-10-22 | 2015-04-30 | Dow Agrosciences Llc | Synergistic pesticidal compositions and related methods |
| MX2016005319A (es) | 2013-10-22 | 2016-08-12 | Dow Agrosciences Llc | Composiciones pesticidas y metodos relacionados. |
| TW201519775A (zh) | 2013-10-22 | 2015-06-01 | Dow Agrosciences Llc | 協同性殺蟲組成物及相關方法(七) |
| AR098092A1 (es) | 2013-10-22 | 2016-05-04 | Dow Agrosciences Llc | Composiciones plaguicidas sinérgicas y los métodos relacionados |
| MX2016005308A (es) | 2013-10-22 | 2016-08-08 | Dow Agrosciences Llc | Composiciones pesticidas sinergicas y metodos relacionados. |
| WO2015061149A1 (en) | 2013-10-22 | 2015-04-30 | Dow Agrosciences Llc | Synergistic pesticidal compositions and related methods |
| NZ720113A (en) | 2013-10-22 | 2017-06-30 | Dow Agrosciences Llc | Synergistic pesticidal compositions and related methods |
| AR098094A1 (es) | 2013-10-22 | 2016-05-04 | Dow Agrosciences Llc | Composiciones plaguicidas sinérgicas y métodos relacionados |
| US9497966B2 (en) | 2013-10-22 | 2016-11-22 | Dow Agrosciences Llc | Pesticidal compositions and related methods |
| BR112016008045B1 (pt) | 2013-10-22 | 2019-12-24 | Dow Agrosciences Llc | composição pesticida |
| US9282740B2 (en) | 2013-10-22 | 2016-03-15 | Dow Agrosciences Llc | Synergistic pesticidal compositions and related methods |
| MX2016005335A (es) | 2013-10-22 | 2017-01-05 | Dow Agrosciences Llc | Composiciones pesticidas y metodos relacionados. |
| NZ719776A (en) | 2013-10-22 | 2017-06-30 | Dow Agrosciences Llc | Synergistic pesticidal compositions and related methods |
| CA2926345A1 (en) | 2013-10-22 | 2015-04-30 | Dow Agrosciences Llc | Synergistic pesticidal compositions and related methods |
| KR20160075624A (ko) | 2013-10-22 | 2016-06-29 | 다우 아그로사이언시즈 엘엘씨 | 살충 조성물 및 관련 방법 |
| RU2667777C2 (ru) | 2013-10-22 | 2018-09-24 | ДАУ АГРОСАЙЕНСИЗ ЭлЭлСи | Пестицидные композиции и связанные с ними способы |
| WO2016018443A1 (en) | 2014-07-31 | 2016-02-04 | Dow Agrosciences Llc | Process for the preparation of 3-(3-chloro-1h-pyrazol-1-yl)pyridine |
| EP3174856A4 (en) | 2014-07-31 | 2018-01-10 | Dow AgroSciences LLC | Process for the preparation of 3-(3-chloro-1h-pyrazol-1-yl)pyridine |
| CN106470976A (zh) | 2014-07-31 | 2017-03-01 | 美国陶氏益农公司 | 制备3‑(3‑氯‑1h‑吡唑‑1‑基)吡啶的方法 |
| WO2016028328A1 (en) | 2014-08-19 | 2016-02-25 | Dow Agrosciences Llc | Process for the preparation of 3-(3-chloro-1h-pyrazol-1-yl)pyridine |
| CN107074775A (zh) | 2014-09-12 | 2017-08-18 | 美国陶氏益农公司 | 3‑(3‑氯‑1h‑吡唑‑1‑基)吡啶的制备方法 |
| JOP20200117A1 (ar) | 2014-10-30 | 2017-06-16 | Janssen Pharmaceutica Nv | كحولات ثلاثي فلوروميثيل كمُعدلات للمستقبل النووي جاما تي المرتبط بحمض الريتيونَويك ROR?t |
| SMT201900706T1 (it) | 2014-10-30 | 2020-01-14 | Janssen Pharmaceutica Nv | Tiazoli sostituiti con ammide come modulatori di rorgammat |
| RS58250B1 (sr) | 2014-10-30 | 2019-03-29 | Janssen Pharmaceutica Nv | Tiazoli kao modulatori roryt |
| JP2018531924A (ja) | 2015-09-24 | 2018-11-01 | ファイザー・インク | テトラヒドロピラノ[3,4−d][1,3]オキサジン誘導体、およびbace阻害剤としてのその使用 |
| TW201803869A (zh) | 2016-04-27 | 2018-02-01 | 健生藥品公司 | 作為RORγT調節劑之6-胺基吡啶-3-基噻唑 |
| US10233155B2 (en) | 2016-12-29 | 2019-03-19 | Dow Agrosciences Llc | Processes for the preparation of pesticide compounds |
| JP2020503336A (ja) | 2016-12-29 | 2020-01-30 | ダウ アグロサイエンシィズ エルエルシー | 殺有害生物化合物の調製方法 |
| BR112019014814B1 (pt) * | 2017-01-23 | 2024-03-12 | Novartis Ag | Compostos, composições farmacêuticas dos mesmos e seus usos no tratamento de doenças associadas à disfunção de canais iônicos de potássio |
| EP3573957B1 (en) * | 2017-01-24 | 2023-04-26 | Rivara, Mirko | Compositions and methods for blocking sodium channels |
| CA3081261A1 (en) | 2017-10-30 | 2019-05-09 | Aptose Biosciences Inc. | Aryl imidazoles for the treatment of cancer |
| ES2928246T3 (es) | 2018-06-18 | 2022-11-16 | Janssen Pharmaceutica Nv | 6-aminopiridin-3-il pirazoles como moduladores de RORyt |
| JP2021527660A (ja) | 2018-06-18 | 2021-10-14 | ヤンセン ファーマシューティカ エヌ.ベー. | RORγtのモジュレータとしてのフェニル及びピリジニル置換イミダゾール |
| US10975037B2 (en) | 2018-06-18 | 2021-04-13 | Janssen Pharmaceutica Nv | Phenyl substituted pyrazoles as modulators of RORγt |
| CN112292373A (zh) | 2018-06-18 | 2021-01-29 | 詹森药业有限公司 | 作为RORγt的调节剂的吡啶基吡唑类 |
| CA3116339A1 (en) | 2018-10-22 | 2020-04-30 | Cadent Therapeutics, Inc. | Crystalline forms of potassium channel modulators |
| US12378203B2 (en) * | 2018-11-01 | 2025-08-05 | Ahammune Biosciences Private Limited | Imidazole compounds, process for the synthesis and uses thereof |
| KR102253652B1 (ko) * | 2019-08-19 | 2021-05-18 | 주식회사 셀젠텍 | 신규한 암전이 억제 활성을 갖는 화합물, 이의 제조방법 및 상기 화합물을 포함하는 암 전이 및 침윤 억제, 또는 암 치료용 약학적 조성물 |
| CN115043779B (zh) * | 2022-06-14 | 2024-06-25 | 广东金柏化学有限公司 | 一种2,4-二苯基咪唑化合物及其制备方法与应用 |
Family Cites Families (46)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL130759C (enExample) * | 1965-10-07 | |||
| NL151519B (nl) | 1966-07-15 | 1976-11-15 | Oce Van Der Grinten Nv | Lichtgevoelig diazotypmateriaal, alsmede de daarin te gebruiken diazoverbindingen. |
| US3546342A (en) | 1966-11-18 | 1970-12-08 | Wyeth John & Brother Ltd | Method of relieving inflammation by administration of 2,4 - diarylthiazole- 5 - alkanoic acids and derivatives thereof |
| GB1145884A (en) | 1966-11-18 | 1969-03-19 | Wyeth John & Brother Ltd | Thiazole derivatives |
| FI53314C (fi) | 1967-06-14 | 1978-04-10 | Wyeth John & Brother Ltd | Foerfarande foer framstaellning av farmaceutiskt anvaendbar 2-(fenyleller p-klorfenyl) oxazol-4-yl (aettiksyra -acetatsalt eller -acetamid) |
| GB1245087A (en) * | 1967-10-26 | 1971-09-02 | Wyeth John & Brother Ltd | Heterocyclic compounds |
| US3528107A (en) * | 1968-07-15 | 1970-09-15 | Harold Rosenbaum | Baseball glove |
| US3575991A (en) | 1969-03-11 | 1971-04-20 | American Home Prod | 1-(4-aryl - 5 - carboxymethyl-2-thiazolyl)-1,6-dihydro -6 - oxonicotinic acids and esters thereof |
| FR2096994A1 (en) | 1970-07-24 | 1972-03-03 | Roussel Uclaf | 2-para-cyclopropyl phenyl-4-(halo)phenyl-5-thiazolyl - alkanoic acids -antiinflammatory analgesic, antipyretic agents |
| FR2146575A5 (enExample) | 1971-07-20 | 1973-03-02 | Labo Braglia Spa | |
| US4127863A (en) * | 1975-10-01 | 1978-11-28 | Tokyo Shibaura Electric Co., Ltd. | Gate turn-off type thyristor with separate semiconductor resistive wafer providing emitter ballast |
| GB1539450A (en) | 1976-06-08 | 1979-01-31 | Wyeth John & Brother Ltd | Thiazole derivatives |
| GB1574583A (en) * | 1978-02-09 | 1980-09-10 | Wyeth John & Brother Ltd | Process for preparing thiazoles |
| GR74148B (enExample) | 1980-04-03 | 1984-06-06 | Wyeth John & Brother Ltd | |
| ZA811691B (en) | 1980-04-03 | 1982-10-27 | Wyeth John & Brother Ltd | Thiazoles |
| JPS57188587A (en) * | 1981-05-15 | 1982-11-19 | Tanabe Seiyaku Co Ltd | Thienyloxazolylacetic acid derivative and its preparation |
| DE3128492A1 (de) | 1981-07-18 | 1983-02-03 | A. Nattermann & Cie GmbH, 5000 Köln | 4-chlorthienyl-5-thiazolalkancarbonsaeure-derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate |
| DE3128453A1 (de) | 1981-07-18 | 1983-02-03 | A. Nattermann & Cie GmbH, 5000 Köln | 4-chlorthienyl-2-thienyl-4-thiazolalkancarbonsaeure-derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate |
| JPS58148882A (ja) * | 1982-02-26 | 1983-09-05 | Tanabe Seiyaku Co Ltd | フリルオキサゾリル酢酸誘導体及びその製法 |
| JPS58183676A (ja) | 1982-04-19 | 1983-10-26 | Takeda Chem Ind Ltd | オキサゾ−ル誘導体 |
| US4486436A (en) * | 1982-07-22 | 1984-12-04 | Analgesic Associates | Analgesic and anti-inflammatory compositions comprising caffeine and methods of using same |
| JPS5936614A (ja) * | 1982-08-25 | 1984-02-28 | Tanabe Seiyaku Co Ltd | 抗脂血剤 |
| JPS59152382A (ja) * | 1983-02-18 | 1984-08-31 | Tanabe Seiyaku Co Ltd | フリルオキサゾリル酢酸誘導体 |
| JPS59172488A (ja) * | 1983-03-18 | 1984-09-29 | Tanabe Seiyaku Co Ltd | 抗脂血剤 |
| JPS60188371A (ja) | 1984-03-07 | 1985-09-25 | Tanabe Seiyaku Co Ltd | イミダゾール誘導体 |
| JPS60202820A (ja) * | 1984-03-27 | 1985-10-14 | Tanabe Seiyaku Co Ltd | 抗脂血剤 |
| DE3425118A1 (de) * | 1984-07-07 | 1986-01-16 | Boehringer Mannheim Gmbh, 6800 Mannheim | Neue redox-indikatoren |
| JPS61167676A (ja) * | 1985-01-21 | 1986-07-29 | Tanabe Seiyaku Co Ltd | アゾ−ル類化合物及びその製法 |
| JPS61167685A (ja) | 1985-01-21 | 1986-07-29 | Tanabe Seiyaku Co Ltd | テトラゾ−ル誘導体およびその製法 |
| GB8531608D0 (en) | 1985-12-23 | 1986-02-05 | Beecham Group Plc | Treatment |
| JPH03258770A (ja) * | 1990-03-08 | 1991-11-19 | Tanabe Seiyaku Co Ltd | ベンズアゾール誘導体、その製法及びその合成中間体 |
| JPH04117371A (ja) * | 1990-09-05 | 1992-04-17 | Otsuka Pharmaceut Factory Inc | チアゾール誘導体 |
| DE69104961T2 (de) | 1990-12-06 | 1995-03-16 | Roussel Uclaf | Anwendung von Thiazolylalkoxyacrylaten in der Herstellung von Insektiziden und/oder Akanizide-Zusammensetzungen. |
| EP0548680B1 (en) | 1991-12-26 | 1998-02-25 | Mitsubishi Chemical Corporation | Beta-oxo-beta-benzenepropanethioamide derivatives |
| US5340826A (en) | 1993-02-04 | 1994-08-23 | Pfizer Inc. | Pharmaceutical agents for treatment of urinary incontinence |
| JPH07173141A (ja) | 1993-08-10 | 1995-07-11 | Nissan Chem Ind Ltd | 新規ピリミジン誘導体及び除草、植調剤 |
| JPH07291936A (ja) * | 1994-03-01 | 1995-11-07 | Kyorin Pharmaceut Co Ltd | 新規イミダゾール誘導体及びその製造法 |
| JP3160910B2 (ja) | 1995-06-07 | 2001-04-25 | 日本新薬株式会社 | ピロール誘導体及び医薬組成物 |
| DE69728581D1 (de) | 1996-01-22 | 2004-05-13 | Fujisawa Pharmaceutical Co | Thiazolylbenzofuranderivate und ihre Verwendung als SRS-A- und Leukotrien-Antagonisten |
| US5677321A (en) * | 1996-02-29 | 1997-10-14 | Synaptic Pharmaceutical Corporation | 5- and 6-(2-imidazolin-2-ylamino) and -(2-thiazolin-2-ylamino)-benzothiazoles as alpha-2 adrenergic ligands |
| DK0891340T3 (da) | 1996-04-03 | 2003-03-10 | Takeda Chemical Industries Ltd | Oxazolderivater samt fremstilling og anvendelse deraf |
| TW467902B (en) | 1996-07-31 | 2001-12-11 | Bristol Myers Squibb Co | Diphenyl heterocycles as potassium channel modulators |
| CA2294898A1 (en) | 1997-07-03 | 1999-01-14 | Neurogen Corporation | Certain diarylimidazole derivatives; a new class of npy specific ligands |
| GB9726989D0 (en) | 1997-12-22 | 1998-02-18 | Ciba Geigy Ag | Organic compounds |
| UA58579C2 (uk) | 1998-01-29 | 2003-08-15 | Брістол-Майерс Сквібб Компані | Похідні 1,3,4-оксадіазолону та фармацевтична композиція на їх основі |
| AU738200B2 (en) | 1998-03-30 | 2001-09-13 | Japan Tobacco Inc. | Production method of isoxazolidinedione compound |
-
2002
- 2002-04-15 EP EP02714577A patent/EP1432690A2/en not_active Withdrawn
- 2002-04-15 PL PL02367325A patent/PL367325A1/xx unknown
- 2002-04-15 BR BR0208956-4A patent/BR0208956A/pt not_active IP Right Cessation
- 2002-04-15 WO PCT/JP2002/003723 patent/WO2002083111A2/en not_active Ceased
- 2002-04-15 AU AU2002246397A patent/AU2002246397B2/en not_active Ceased
- 2002-04-15 HU HU0303829A patent/HUP0303829A3/hu unknown
- 2002-04-15 CN CNA200910004656XA patent/CN101519386A/zh active Pending
- 2002-04-15 US US10/474,850 patent/US7759373B2/en not_active Expired - Fee Related
- 2002-04-15 CN CNB028083709A patent/CN100540538C/zh not_active Expired - Fee Related
- 2002-04-15 KR KR1020037013493A patent/KR100863659B1/ko not_active Expired - Fee Related
- 2002-04-15 CA CA002444596A patent/CA2444596A1/en not_active Abandoned
- 2002-04-15 JP JP2002580915A patent/JP4073786B2/ja not_active Expired - Fee Related
- 2002-04-15 CZ CZ20032829A patent/CZ20032829A3/cs unknown
- 2002-04-15 IL IL15816802A patent/IL158168A0/xx unknown
- 2002-04-15 NZ NZ529043A patent/NZ529043A/en unknown
- 2002-04-16 TW TW098138199A patent/TW201006831A/zh unknown
- 2002-04-16 AR ARP020101381A patent/AR035828A1/es unknown
- 2002-04-16 TW TW091107687A patent/TWI322686B/zh not_active IP Right Cessation
-
2003
- 2003-10-15 MX MXPA03009440A patent/MXPA03009440A/es active IP Right Grant
-
2007
- 2007-09-18 JP JP2007241012A patent/JP2008044952A/ja active Pending
-
2010
- 2010-06-07 US US12/795,323 patent/US20100256165A1/en not_active Abandoned
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2008044952A5 (enExample) | ||
| JP2007522220A5 (enExample) | ||
| WO2005046589A3 (en) | Pharmaceutically acceptable salts of quinolinone compounds having improved pharmaceutical properties | |
| EP2592070A3 (en) | Tetrazole-substituted arylamides | |
| JP2007269812A5 (enExample) | ||
| JP2006515626A5 (enExample) | ||
| JP2007077157A5 (enExample) | ||
| JP2011502958A5 (enExample) | ||
| JP2005526081A5 (ja) | 代謝型グルタメート受容体−5の二アリール置換テトラゾールモジュレータ | |
| JP2010526814A5 (enExample) | ||
| JP2005518413A5 (enExample) | ||
| JP2008510828A5 (enExample) | ||
| IL205974A (en) | 2- (5-Bromo-4- (4-Cyclopropylphenaphthalene-1-ram) -4 h-4,2,1- Triazole-3-Ilthio) Acetic acid or salt is acceptable in its pharmacy for use as a drug and a pharmaceutical preparation containing this compound | |
| MX2009009492A (es) | Compuestos organicos biciclicos adecuados para el tratamiento de condiciones inflamatorias o alergicas. | |
| WO2008075068A3 (en) | Acylaminopyrazoles as fgfr inhibitors | |
| WO2007048064A3 (en) | Amino-pyrimidines as casein kinase ii (ck2) modulators | |
| JP2011513410A5 (enExample) | ||
| EP2620432A3 (en) | Diarylhydantoin compounds | |
| JP2009513564A5 (enExample) | ||
| JP2011527666A5 (enExample) | ||
| JP2012512863A5 (enExample) | ||
| EA201270099A1 (ru) | Транс-4-[[(5s)-5-[[[3,5-бис(трифторметил)фенил]метил](2-метил-2h-тетразол-5-ил)амино]-2,3,4,5-тетрагидро-7,9-диметил-1h-1-бензазепин-1-ил]метил]циклогексанкарбоновая кислота | |
| JP2009184932A5 (enExample) | ||
| JP2007502817A5 (enExample) | ||
| JP2013544854A5 (enExample) |