JP2012512863A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2012512863A5 JP2012512863A5 JP2011541665A JP2011541665A JP2012512863A5 JP 2012512863 A5 JP2012512863 A5 JP 2012512863A5 JP 2011541665 A JP2011541665 A JP 2011541665A JP 2011541665 A JP2011541665 A JP 2011541665A JP 2012512863 A5 JP2012512863 A5 JP 2012512863A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutically acceptable
- acceptable salt
- compound according
- hydrogen
- methyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 150000001875 compounds Chemical class 0.000 claims 12
- 150000003839 salts Chemical class 0.000 claims 11
- 229910052739 hydrogen Inorganic materials 0.000 claims 7
- 239000001257 hydrogen Substances 0.000 claims 7
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims 6
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 5
- 125000001424 substituent group Chemical group 0.000 claims 4
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 claims 2
- YZCKVEUIGOORGS-OUBTZVSYSA-N Deuterium Chemical group [2H] YZCKVEUIGOORGS-OUBTZVSYSA-N 0.000 claims 2
- 229910052805 deuterium Inorganic materials 0.000 claims 2
- 125000005843 halogen group Chemical group 0.000 claims 2
- 125000005842 heteroatom Chemical group 0.000 claims 2
- 125000000623 heterocyclic group Chemical group 0.000 claims 2
- 150000002431 hydrogen Chemical group 0.000 claims 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 2
- 229910052757 nitrogen Inorganic materials 0.000 claims 2
- 229910052717 sulfur Inorganic materials 0.000 claims 2
- 125000004191 (C1-C6) alkoxy group Chemical group 0.000 claims 1
- 125000003341 7 membered heterocyclic group Chemical group 0.000 claims 1
- 239000003242 anti bacterial agent Substances 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 229910052760 oxygen Inorganic materials 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US13915908P | 2008-12-19 | 2008-12-19 | |
| US61/139,159 | 2008-12-19 | ||
| PCT/IB2009/055544 WO2010070523A1 (en) | 2008-12-19 | 2009-12-07 | Monocarbams |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2012512863A JP2012512863A (ja) | 2012-06-07 |
| JP2012512863A5 true JP2012512863A5 (enExample) | 2012-12-06 |
Family
ID=41727494
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011541665A Pending JP2012512863A (ja) | 2008-12-19 | 2009-12-07 | モノカルバム |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US8252782B2 (enExample) |
| EP (1) | EP2379546A1 (enExample) |
| JP (1) | JP2012512863A (enExample) |
| KR (1) | KR20110086742A (enExample) |
| CN (1) | CN102325769A (enExample) |
| AR (1) | AR074801A1 (enExample) |
| AU (1) | AU2009329169B2 (enExample) |
| CA (1) | CA2744756C (enExample) |
| IL (1) | IL213216A0 (enExample) |
| MX (1) | MX2011006541A (enExample) |
| PA (1) | PA8855001A1 (enExample) |
| SG (1) | SG171781A1 (enExample) |
| TW (1) | TW201026696A (enExample) |
| UY (1) | UY32336A (enExample) |
| WO (1) | WO2010070523A1 (enExample) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2744756C (en) * | 2008-12-19 | 2013-05-28 | Pfizer Inc. | Monocarbams and their use as antibacterial agent |
| JP5777725B2 (ja) | 2010-11-29 | 2015-09-09 | ファイザー・インク | モノバクタム |
| UY34585A (es) * | 2012-01-24 | 2013-09-02 | Aicuris Gmbh & Co Kg | Compuestos b-lactámicos sustituidos con amidina, su preparación y uso |
| AU2016327264B2 (en) | 2015-09-23 | 2019-06-27 | Novartis Ag | Salts and solid forms of monobactam antibiotic |
| CN105481812B (zh) * | 2015-11-30 | 2020-04-21 | 重庆天奕恒化科技有限公司 | 一种5-苄氧基-4-氧代-4h-吡喃-2-羧酸的制备方法 |
| CN110312715A (zh) | 2016-12-21 | 2019-10-08 | 艾库里斯有限及两合公司 | 用于抗生素耐药性细菌菌株感染的使用脒取代的β-内酰胺化合物和β-内酰胺酶抑制剂的组合疗法 |
| ES2912656T3 (es) | 2017-08-02 | 2022-05-26 | Novartis Ag | Proceso para preparar ácido 1-(((Z)-(1-(2-aminotiazol-4-il)-2-oxo-2-(((3S,4R)-2-oxo-4-((2-oxooxazolidin-3-il)metil)-1-sulfoacetidin-3-il)amino)etiliden)amino)oxi)ciclopropano carboxílico |
| US11034648B2 (en) | 2017-08-23 | 2021-06-15 | Helmholtz-Zentrum Für | Cystobactamide derivatives |
| WO2019045085A1 (ja) | 2017-08-31 | 2019-03-07 | 北興化学工業株式会社 | １－（ｎ，ｎ－ジ置換カルバモイル）４－（置換スルホニル）トリアゾリン－５－オン誘導体、４－（ｎ，ｎ－ジ置換カルバモイル）１－（置換スルホニル）トリアゾリン－５－オン誘導体、およびそれらを有効成分として含有する除草剤 |
| EP3747883A4 (en) | 2018-01-29 | 2020-12-16 | Medshine Discovery Inc. | MONOCYCLIC B-LACTAM COMPOUND FOR TREATING BACTERIAL INFECTION |
| WO2020125670A1 (zh) | 2018-12-18 | 2020-06-25 | 南京明德新药研发有限公司 | 单环β-内酰胺化合物在制药中的应用 |
| US12491180B2 (en) | 2019-12-19 | 2025-12-09 | Shenzhen Optimum Biological Technology Co., Ltd | Application of compound in treating pneumonia |
| JP2025513455A (ja) | 2022-04-22 | 2025-04-24 | バーテックス ファーマシューティカルズ インコーポレイテッド | 疼痛の治療のためのヘテロアリール化合物 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ199981A (en) | 1981-04-09 | 1985-08-16 | Squibb & Sons Inc | 2-oxo-1-(((substituted sulphonyl)amino)carbonyl)azetidines |
| US4587047A (en) * | 1981-04-09 | 1986-05-06 | E. R. Squibb & Sons, Inc. | 2-oxo-1-[[(substituted sulfonyl)amino]-carbonyl]azetidines |
| US5006650A (en) * | 1987-02-11 | 1991-04-09 | The Upjohn Company | Novel N-1 substituted beta-lactams as antibiotics |
| DE3864257D1 (de) | 1987-02-11 | 1991-09-19 | Upjohn Co | Neue n-1 substituierte beta-lactame als antibiotika. |
| US5001235A (en) * | 1987-02-27 | 1991-03-19 | The Upjohn Company | Antibiotic beta-lactams containing a pyridone carboxylic acid or acid derivative |
| CA1317298C (en) * | 1987-03-03 | 1993-05-04 | Upjohn Company (The) | Antibiotic sulfonylaminocarbonyl activated .beta.-lactams |
| US4762922A (en) * | 1987-07-01 | 1988-08-09 | Squibb Corporation | 2-oxo-1-[[(substituted sulfonyl)amino]-carbonyl]azetidines |
| US5015737A (en) * | 1987-07-22 | 1991-05-14 | The Upjohn Company | Therapeutically useful beta-lactams |
| US4777252A (en) * | 1987-08-13 | 1988-10-11 | E. R. Squibb & Sons, Inc. | 2-oxo-1-[[(substituted sulfonyl)amino]-carbonyl]azetidines |
| US4889930A (en) | 1987-12-21 | 1989-12-26 | E. R. Squibb & Sons, Inc. | Process for making 2-oxo-1-((substituted sulfonyl)amino)carbonzyl)azetidines and intermediates used therein |
| JPH01305081A (ja) | 1988-04-04 | 1989-12-08 | E R Squibb & Sons Inc | ３―アシルアミノ―１―［［［（置換スルホニル）アミノ〕カルボニル〕アミノ〕―２―アゼチジノン類 |
| EP0344707A3 (en) | 1988-06-02 | 1990-04-18 | E.R. Squibb & Sons, Inc. | 2-Oxo-1-[[(substituted sulfonyl)-amino]carbonyl]-azetidine derivatives |
| US4959470A (en) * | 1988-08-17 | 1990-09-25 | E. R. Squibb & Sons, Inc. | 2-oxo-[[(substituted sulfonyl)-amino]carbonyl]-azetidines |
| EP0436568A1 (en) | 1988-09-27 | 1991-07-17 | The Upjohn Company | Dihydroxyaryl 4-substituted monocarbams as antibiotics |
| CA2210787A1 (en) | 1997-07-17 | 1999-01-17 | William R. Collier | Self-contained work station |
| BRPI0809147A2 (pt) | 2007-03-23 | 2014-08-26 | Basilea Pharmaceutica Ag | Medicamentos combinados para tratamento de infecções bacterianas |
| CA2744756C (en) * | 2008-12-19 | 2013-05-28 | Pfizer Inc. | Monocarbams and their use as antibacterial agent |
-
2009
- 2009-12-07 CA CA2744756A patent/CA2744756C/en not_active Expired - Fee Related
- 2009-12-07 CN CN2009801569587A patent/CN102325769A/zh active Pending
- 2009-12-07 AU AU2009329169A patent/AU2009329169B2/en not_active Ceased
- 2009-12-07 JP JP2011541665A patent/JP2012512863A/ja active Pending
- 2009-12-07 MX MX2011006541A patent/MX2011006541A/es active IP Right Grant
- 2009-12-07 KR KR1020117013944A patent/KR20110086742A/ko not_active Abandoned
- 2009-12-07 SG SG2011036704A patent/SG171781A1/en unknown
- 2009-12-07 WO PCT/IB2009/055544 patent/WO2010070523A1/en not_active Ceased
- 2009-12-07 EP EP09795553A patent/EP2379546A1/en not_active Withdrawn
- 2009-12-17 UY UY0001032336A patent/UY32336A/es not_active Application Discontinuation
- 2009-12-18 TW TW098143723A patent/TW201026696A/zh unknown
- 2009-12-18 US US12/641,343 patent/US8252782B2/en not_active Expired - Fee Related
- 2009-12-18 PA PA20098855001A patent/PA8855001A1/es unknown
- 2009-12-18 AR ARP090104977A patent/AR074801A1/es not_active Application Discontinuation
-
2011
- 2011-05-30 IL IL213216A patent/IL213216A0/en unknown
-
2012
- 2012-07-26 US US13/558,989 patent/US8324198B1/en not_active Expired - Fee Related
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2013507423A5 (enExample) | ||
| JP2011518833A5 (enExample) | ||
| MY162940A (en) | Quinoline derivative-containing pharmaceutical composition | |
| JP2013512277A5 (enExample) | ||
| JP2013537203A5 (enExample) | ||
| JP2010529147A5 (enExample) | ||
| PH12017501192B1 (en) | Certain amino-pyridazines, compositions thereof, and methods of their use | |
| JP2011037901A5 (enExample) | ||
| CA2744756A1 (en) | Monocarbams and their use as antibacterial agent | |
| JP2007302689A5 (enExample) | ||
| ME02558B (me) | Inhibitori replikacije virusa gripa | |
| JP2015500843A5 (enExample) | ||
| JP2010504286A5 (enExample) | ||
| PH12016502037B1 (en) | Certain amino-pyrimidines, compositions thereof, and methods for their use | |
| JP2009535307A5 (enExample) | ||
| JP2011500658A5 (enExample) | ||
| JP2011105738A5 (enExample) | ||
| WO2009156861A3 (en) | Substituted pyrimidone derivatives | |
| JP2013544276A5 (enExample) | ||
| GB201201744D0 (en) | Novel compounds | |
| JP2014508804A5 (enExample) | ||
| JP2014507477A5 (enExample) | ||
| NZ596820A (en) | Trans-4-[[(5s)-5-[[[3,5-bis(trifluoromethyl)phenyl]methyl] (2-methyl-2h-tetrazol-5-yl)amino]-2,3,4,5-tetrahydro-7,9-dimethyl-1h-1-benzazepin-1-yl]methyl]-cyclohexanecarboxylic acid | |
| JP2014516033A5 (enExample) | ||
| JP2013544854A5 (enExample) |