PA8855001A1 - Monocarbamas - Google Patents

Monocarbamas

Info

Publication number
PA8855001A1
PA8855001A1 PA20098855001A PA8855001A PA8855001A1 PA 8855001 A1 PA8855001 A1 PA 8855001A1 PA 20098855001 A PA20098855001 A PA 20098855001A PA 8855001 A PA8855001 A PA 8855001A PA 8855001 A1 PA8855001 A1 PA 8855001A1
Authority
PA
Panama
Prior art keywords
monocarbamas
compounds
formula
refers
memory
Prior art date
Application number
PA20098855001A
Other languages
English (en)
Inventor
Singh Lall Manjinder
Edward Flanagan Mark
Joseph Brickner Steven
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of PA8855001A1 publication Critical patent/PA8855001A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Abstract

LA INVENCIÓN SE REFIERE A COMPUESTOS DE LA FÓRMULA (1): EN LA QUE R1, R2, R3, R4, R5, Y R6 SON COMO SE DEFINEN EN LA PRESENTE MEMORIA. LA INVENCIÓN TAMBIÉN SE REFIERE A COMPOSICIONES FARMACÉUTICAS Y A MÉTODOS PARA TRATAR INFECCIONES BACTERIANAS USANDO LOS COMPUESTOS DE LA FÓRMULA (1).
PA20098855001A 2008-12-19 2009-12-18 Monocarbamas PA8855001A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US13915908P 2008-12-19 2008-12-19

Publications (1)

Publication Number Publication Date
PA8855001A1 true PA8855001A1 (es) 2010-07-27

Family

ID=41727494

Family Applications (1)

Application Number Title Priority Date Filing Date
PA20098855001A PA8855001A1 (es) 2008-12-19 2009-12-18 Monocarbamas

Country Status (15)

Country Link
US (2) US8252782B2 (es)
EP (1) EP2379546A1 (es)
JP (1) JP2012512863A (es)
KR (1) KR20110086742A (es)
CN (1) CN102325769A (es)
AR (1) AR074801A1 (es)
AU (1) AU2009329169B2 (es)
CA (1) CA2744756C (es)
IL (1) IL213216A0 (es)
MX (1) MX2011006541A (es)
PA (1) PA8855001A1 (es)
SG (1) SG171781A1 (es)
TW (1) TW201026696A (es)
UY (1) UY32336A (es)
WO (1) WO2010070523A1 (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2009329169B2 (en) * 2008-12-19 2012-06-28 Pfizer Inc. Monocarbams
SG190007A1 (en) * 2010-11-29 2013-06-28 Pfizer Monobactams
UY34585A (es) 2012-01-24 2013-09-02 Aicuris Gmbh & Co Kg Compuestos b-lactámicos sustituidos con amidina, su preparación y uso
US10919887B2 (en) * 2015-09-23 2021-02-16 Novartis Ag Salts and solid forms of a monobactam antibiotic
CN105481812B (zh) * 2015-11-30 2020-04-21 重庆天奕恒化科技有限公司 一种5-苄氧基-4-氧代-4h-吡喃-2-羧酸的制备方法
BR112019012994A2 (pt) 2016-12-21 2019-12-03 Aicuris Gmbh & Co Kg terapia de combinação com compostos de b-lactama de amidina substituída e inibidores de b-lactamase para infecções com cepas bacterianas resistentes a antibiótico
ES2912656T3 (es) 2017-08-02 2022-05-26 Novartis Ag Proceso para preparar ácido 1-(((Z)-(1-(2-aminotiazol-4-il)-2-oxo-2-(((3S,4R)-2-oxo-4-((2-oxooxazolidin-3-il)metil)-1-sulfoacetidin-3-il)amino)etiliden)amino)oxi)ciclopropano carboxílico
AU2018321152B2 (en) 2017-08-23 2023-07-06 Helmholtz-Zentrum für Infektionsforschung GmbH Novel cystobactamide derivatives
CN111328327A (zh) 2017-08-31 2020-06-23 北兴化学工业株式会社 1-(n,n-二取代的氨基甲酰基)4-(取代的磺酰基)三唑啉-5-酮衍生物、4-(n,n-二取代的氨基甲酰基)1-(取代的磺酰基)三唑啉-5-酮衍生物和包含这些衍生物作为有效成分的除草剂
CN111511737B (zh) 2018-01-29 2022-10-18 南京明德新药研发有限公司 用于治疗细菌感染的单环β-内酰胺化合物
US20230022708A1 (en) 2019-12-19 2023-01-26 Medshine Discovery Inc. Application of compound in drug preparation

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4587047A (en) * 1981-04-09 1986-05-06 E. R. Squibb & Sons, Inc. 2-oxo-1-[[(substituted sulfonyl)amino]-carbonyl]azetidines
NZ199981A (en) 1981-04-09 1985-08-16 Squibb & Sons Inc 2-oxo-1-(((substituted sulphonyl)amino)carbonyl)azetidines
US5006650A (en) * 1987-02-11 1991-04-09 The Upjohn Company Novel N-1 substituted beta-lactams as antibiotics
AU602067B2 (en) 1987-02-11 1990-09-27 Upjohn Company, The Novel n-1 substituted beta-lactams as antibiotics
EP0357604A1 (en) * 1987-02-27 1990-03-14 The Upjohn Company Antibiotic beta-lactams containing a pyridone carboxylic acid or acid derivative
CA1317298C (en) 1987-03-03 1993-05-04 Upjohn Company (The) Antibiotic sulfonylaminocarbonyl activated .beta.-lactams
US4762922A (en) * 1987-07-01 1988-08-09 Squibb Corporation 2-oxo-1-[[(substituted sulfonyl)amino]-carbonyl]azetidines
US5015737A (en) * 1987-07-22 1991-05-14 The Upjohn Company Therapeutically useful beta-lactams
US4777252A (en) 1987-08-13 1988-10-11 E. R. Squibb & Sons, Inc. 2-oxo-1-[[(substituted sulfonyl)amino]-carbonyl]azetidines
US4889930A (en) 1987-12-21 1989-12-26 E. R. Squibb & Sons, Inc. Process for making 2-oxo-1-((substituted sulfonyl)amino)carbonzyl)azetidines and intermediates used therein
JPH01305081A (ja) 1988-04-04 1989-12-08 E R Squibb & Sons Inc ３―アシルアミノ―１―［［［（置換スルホニル）アミノ〕カルボニル〕アミノ〕―２―アゼチジノン類
EP0344707A3 (en) 1988-06-02 1990-04-18 E.R. Squibb & Sons, Inc. 2-Oxo-1-[[(substituted sulfonyl)-amino]carbonyl]-azetidine derivatives
US4959470A (en) 1988-08-17 1990-09-25 E. R. Squibb & Sons, Inc. 2-oxo-[[(substituted sulfonyl)-amino]carbonyl]-azetidines
EP0436568A1 (en) 1988-09-27 1991-07-17 The Upjohn Company Dihydroxyaryl 4-substituted monocarbams as antibiotics
CA2210787A1 (en) 1997-07-17 1999-01-17 William R. Collier Self-contained work station
BRPI0809147A2 (pt) 2007-03-23 2014-08-26 Basilea Pharmaceutica Ag Medicamentos combinados para tratamento de infecções bacterianas
AU2009329169B2 (en) * 2008-12-19 2012-06-28 Pfizer Inc. Monocarbams

Also Published As

Publication number Publication date
AR074801A1 (es) 2011-02-16
WO2010070523A1 (en) 2010-06-24
JP2012512863A (ja) 2012-06-07
CA2744756A1 (en) 2010-06-24
CN102325769A (zh) 2012-01-18
IL213216A0 (en) 2011-07-31
SG171781A1 (en) 2011-07-28
AU2009329169A1 (en) 2010-06-24
US8324198B1 (en) 2012-12-04
US8252782B2 (en) 2012-08-28
TW201026696A (en) 2010-07-16
UY32336A (es) 2010-07-30
KR20110086742A (ko) 2011-07-29
MX2011006541A (es) 2011-07-20
EP2379546A1 (en) 2011-10-26
US20100160281A1 (en) 2010-06-24
CA2744756C (en) 2013-05-28
AU2009329169B2 (en) 2012-06-28
US20120289455A1 (en) 2012-11-15

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