JP2013544854A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2013544854A5 JP2013544854A5 JP2013542356A JP2013542356A JP2013544854A5 JP 2013544854 A5 JP2013544854 A5 JP 2013544854A5 JP 2013542356 A JP2013542356 A JP 2013542356A JP 2013542356 A JP2013542356 A JP 2013542356A JP 2013544854 A5 JP2013544854 A5 JP 2013544854A5
- Authority
- JP
- Japan
- Prior art keywords
- heteroaryl
- group
- independently selected
- compound
- substituents
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 0 CC(C)(*)CC(C)(C)*C(C(*)=C*1N)=NC1=O Chemical compound CC(C)(*)CC(C)(C)*C(C(*)=C*1N)=NC1=O 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2010079463 | 2010-12-06 | ||
| CNPCT/CN2010/079463 | 2010-12-06 | ||
| PCT/CN2011/083465 WO2012075917A1 (en) | 2010-12-06 | 2011-12-05 | Compounds |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2013544854A JP2013544854A (ja) | 2013-12-19 |
| JP2013544854A5 true JP2013544854A5 (enExample) | 2015-01-29 |
Family
ID=46206620
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013542356A Withdrawn JP2013544854A (ja) | 2010-12-06 | 2011-12-05 | 化合物 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US8859573B2 (enExample) |
| EP (1) | EP2649050A4 (enExample) |
| JP (1) | JP2013544854A (enExample) |
| WO (1) | WO2012075917A1 (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101861883B1 (ko) * | 2010-12-06 | 2018-05-28 | 글락소 그룹 리미티드 | Lp-PLA₂에 의해 매개되는 질환 또는 상태의 치료에 사용하기 위한 피리미디논 화합물 |
| LT2751094T (lt) | 2011-09-01 | 2018-11-12 | Glaxo Group Limited | Naujoji kristalinė forma |
| AR092742A1 (es) | 2012-10-02 | 2015-04-29 | Intermune Inc | Piridinonas antifibroticas |
| CN104684900B (zh) | 2012-10-25 | 2017-04-12 | 沈阳中化农药化工研发有限公司 | 取代嘧啶类化合物及其用途 |
| MX2015009633A (es) * | 2013-01-25 | 2015-11-30 | Glaxosmithkline Ip Dev Ltd | Inhibidores de fosfolipasa a2 asociada con lipoproteinas basados en 2,3-dihidroimidazol[1,2-c] pirimidin-5(1h)-ona. |
| EP2948456A4 (en) * | 2013-01-25 | 2016-09-14 | Glaxosmithkline Ip Dev Ltd | BICYCLIC PYRIMIDONE COMPOUNDS AS LP-PLA2 INHIBITORS |
| EP2764866A1 (en) | 2013-02-07 | 2014-08-13 | IP Gesellschaft für Management mbH | Inhibitors of nedd8-activating enzyme |
| US10233195B2 (en) | 2014-04-02 | 2019-03-19 | Intermune, Inc. | Anti-fibrotic pyridinones |
| CN105777653A (zh) * | 2014-12-26 | 2016-07-20 | 中国科学院上海药物研究所 | 用作Lp-PLA2抑制剂的嘧啶酮类化合物及其药物组合物 |
| WO2025015951A1 (zh) | 2023-07-17 | 2025-01-23 | 上海枢境生物科技有限公司 | 双环[5,6]咪唑嘧啶酮类衍生物、其制备方法和应用 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2203988T3 (es) * | 1997-11-06 | 2004-04-16 | Smithkline Beecham Plc | Compuestos de pirimidinona y composiciones farmaceuticas que los contienen. |
| WO2000010980A1 (en) | 1998-08-21 | 2000-03-02 | Smithkline Beecham Plc | Pyrimidinone derivatives for the treatment of atherosclerosis |
| DK1263740T3 (da) * | 2000-02-16 | 2006-11-13 | Smithkline Beecham Plc | Pyrimidin-4-on-derivat som LDL-PLA2-inhibitor |
| GB0024808D0 (en) * | 2000-10-10 | 2000-11-22 | Smithkline Beecham Plc | Novel compounds |
| AU2002228922A1 (en) * | 2000-12-12 | 2002-06-24 | Cytovia, Inc. | Substituted 2-aryl-4-arylaminopyrimidines and analogs as activators of caspases and inducers of apoptosis and the use thereof |
| US7973060B2 (en) * | 2005-10-13 | 2011-07-05 | Crystalgenomics, Inc. | Fab I inhibitor and process for preparing same |
| KR101861883B1 (ko) * | 2010-12-06 | 2018-05-28 | 글락소 그룹 리미티드 | Lp-PLA₂에 의해 매개되는 질환 또는 상태의 치료에 사용하기 위한 피리미디논 화합물 |
-
2011
- 2011-12-05 JP JP2013542356A patent/JP2013544854A/ja not_active Withdrawn
- 2011-12-05 US US13/991,953 patent/US8859573B2/en not_active Expired - Fee Related
- 2011-12-05 EP EP11847368.5A patent/EP2649050A4/en not_active Withdrawn
- 2011-12-05 WO PCT/CN2011/083465 patent/WO2012075917A1/en not_active Ceased