JP2013544854A5 - - Google Patents
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- Publication number
- JP2013544854A5 JP2013544854A5 JP2013542356A JP2013542356A JP2013544854A5 JP 2013544854 A5 JP2013544854 A5 JP 2013544854A5 JP 2013542356 A JP2013542356 A JP 2013542356A JP 2013542356 A JP2013542356 A JP 2013542356A JP 2013544854 A5 JP2013544854 A5 JP 2013544854A5
- Authority
- JP
- Japan
- Prior art keywords
- heteroaryl
- group
- independently selected
- compound
- substituents
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 0 CC(C)(*)CC(C)(C)*C(C(*)=C*1N)=NC1=O Chemical compound CC(C)(*)CC(C)(C)*C(C(*)=C*1N)=NC1=O 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2010079463 | 2010-12-06 | ||
| CNPCT/CN2010/079463 | 2010-12-06 | ||
| PCT/CN2011/083465 WO2012075917A1 (en) | 2010-12-06 | 2011-12-05 | Compounds |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2013544854A JP2013544854A (ja) | 2013-12-19 |
| JP2013544854A5 true JP2013544854A5 (enExample) | 2015-01-29 |
Family
ID=46206620
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013542356A Withdrawn JP2013544854A (ja) | 2010-12-06 | 2011-12-05 | 化合物 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US8859573B2 (enExample) |
| EP (1) | EP2649050A4 (enExample) |
| JP (1) | JP2013544854A (enExample) |
| WO (1) | WO2012075917A1 (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2011340690C1 (en) * | 2010-12-06 | 2016-03-10 | Glaxo Group Limited | Pyrimidinone compounds for use in the treatment of diseases or conditions mediated by Lp - PLA2 |
| SG2014011886A (en) | 2011-09-01 | 2014-05-29 | Glaxo Group Ltd | Novel crystal form |
| AR092742A1 (es) | 2012-10-02 | 2015-04-29 | Intermune Inc | Piridinonas antifibroticas |
| US9770026B2 (en) | 2012-10-25 | 2017-09-26 | Shenyang Sinochem Agrochemicals R&D Co., Ltd. | Substituted pyrimidine compound and uses thereof |
| AU2014210260B2 (en) * | 2013-01-25 | 2016-08-04 | Glaxosmithkline Intellectual Property Development Limited | Bicyclic pyrimidone compounds as inhibitors of Lp-PLA2 |
| KR20150108897A (ko) * | 2013-01-25 | 2015-09-30 | 글락소스미스클라인 인털렉츄얼 프로퍼티 디벨로프먼트 리미티드 | 2,3-디히드로이미다졸[1,2-c]피리미딘-5(1h)-온계의 지단백질-연관 포스포리파제 a2 (lp-pla2) 억제제 |
| EP2764866A1 (en) | 2013-02-07 | 2014-08-13 | IP Gesellschaft für Management mbH | Inhibitors of nedd8-activating enzyme |
| JP6525437B2 (ja) | 2014-04-02 | 2019-06-05 | インターミューン， インコーポレイテッド | 抗線維性ピリジノン |
| CN105777653A (zh) * | 2014-12-26 | 2016-07-20 | 中国科学院上海药物研究所 | 用作Lp-PLA2抑制剂的嘧啶酮类化合物及其药物组合物 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69816471T2 (de) * | 1997-11-06 | 2004-05-27 | Smithkline Beecham P.L.C., Brentford | Pyrimidinon verbindungen und diese enthaltende pharmazeutische zusammenstellungen |
| JP2002523402A (ja) * | 1998-08-21 | 2002-07-30 | スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー | アテローム性動脈硬化症の治療用ピリミジノン |
| HU229479B1 (en) | 2000-02-16 | 2014-01-28 | Glaxo Group Ltd | Pyrimidine-4-one derivatives |
| GB0024808D0 (en) * | 2000-10-10 | 2000-11-22 | Smithkline Beecham Plc | Novel compounds |
| WO2002047690A1 (en) * | 2000-12-12 | 2002-06-20 | Cytovia, Inc. | Substituted 2-aryl-4-arylaminopyrimidines and analogs as activators of caspases and inducers of apoptosis and the use thereof |
| US7973060B2 (en) | 2005-10-13 | 2011-07-05 | Crystalgenomics, Inc. | Fab I inhibitor and process for preparing same |
| AU2011340690C1 (en) * | 2010-12-06 | 2016-03-10 | Glaxo Group Limited | Pyrimidinone compounds for use in the treatment of diseases or conditions mediated by Lp - PLA2 |
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2011
- 2011-12-05 EP EP11847368.5A patent/EP2649050A4/en not_active Withdrawn
- 2011-12-05 WO PCT/CN2011/083465 patent/WO2012075917A1/en not_active Ceased
- 2011-12-05 US US13/991,953 patent/US8859573B2/en not_active Expired - Fee Related
- 2011-12-05 JP JP2013542356A patent/JP2013544854A/ja not_active Withdrawn