UY32336A - Nuevos compuestos de acido 2-({ [(1Z)-1-2(2-amino-1,3-tiazol-4-il)-2-{ [(3S)-1-({ [5-hidroxi-4-oxo-1,4-dihidropiridin-2-il)-5-oxo-4-propil-4, 5 - dihidro - 1H - 1, 2, 4 - trialzol - 1 - il]sulfonil} carbamoil) -2 - oxazetidin -3 -il] amino} - 2 - oxoetiliden] amino} oxi) - 2 - metilpropanoico, composiciones farmacéuticas conteniendolos y aplicaciones. - Google Patents

Nuevos compuestos de acido 2-({ [(1Z)-1-2(2-amino-1,3-tiazol-4-il)-2-{ [(3S)-1-({ [5-hidroxi-4-oxo-1,4-dihidropiridin-2-il)-5-oxo-4-propil-4, 5 - dihidro - 1H - 1, 2, 4 - trialzol - 1 - il]sulfonil} carbamoil) -2 - oxazetidin -3 -il] amino} - 2 - oxoetiliden] amino} oxi) - 2 - metilpropanoico, composiciones farmacéuticas conteniendolos y aplicaciones.

Info

Publication number
UY32336A
UY32336A UY0001032336A UY32336A UY32336A UY 32336 A UY32336 A UY 32336A UY 0001032336 A UY0001032336 A UY 0001032336A UY 32336 A UY32336 A UY 32336A UY 32336 A UY32336 A UY 32336A
Authority
UY
Uruguay
Prior art keywords
amino
oxo
pharmaceutical compositions
trialzol
oxazetidine
Prior art date
Application number
UY0001032336A
Other languages
English (en)
Spanish (es)
Inventor
Mark Edward Flamagan
Steven Joseph Brickner
Manjinder Singh Lall
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of UY32336A publication Critical patent/UY32336A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Peptides Or Proteins (AREA)
UY0001032336A 2008-12-19 2009-12-17 Nuevos compuestos de acido 2-({ [(1Z)-1-2(2-amino-1,3-tiazol-4-il)-2-{ [(3S)-1-({ [5-hidroxi-4-oxo-1,4-dihidropiridin-2-il)-5-oxo-4-propil-4, 5 - dihidro - 1H - 1, 2, 4 - trialzol - 1 - il]sulfonil} carbamoil) -2 - oxazetidin -3 -il] amino} - 2 - oxoetiliden] amino} oxi) - 2 - metilpropanoico, composiciones farmacéuticas conteniendolos y aplicaciones. UY32336A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US13915908P 2008-12-19 2008-12-19

Publications (1)

Publication Number Publication Date
UY32336A true UY32336A (es) 2010-07-30

Family

ID=41727494

Family Applications (1)

Application Number Title Priority Date Filing Date
UY0001032336A UY32336A (es) 2008-12-19 2009-12-17 Nuevos compuestos de acido 2-({ [(1Z)-1-2(2-amino-1,3-tiazol-4-il)-2-{ [(3S)-1-({ [5-hidroxi-4-oxo-1,4-dihidropiridin-2-il)-5-oxo-4-propil-4, 5 - dihidro - 1H - 1, 2, 4 - trialzol - 1 - il]sulfonil} carbamoil) -2 - oxazetidin -3 -il] amino} - 2 - oxoetiliden] amino} oxi) - 2 - metilpropanoico, composiciones farmacéuticas conteniendolos y aplicaciones.

Country Status (15)

Country Link
US (2) US8252782B2 (enExample)
EP (1) EP2379546A1 (enExample)
JP (1) JP2012512863A (enExample)
KR (1) KR20110086742A (enExample)
CN (1) CN102325769A (enExample)
AR (1) AR074801A1 (enExample)
AU (1) AU2009329169B2 (enExample)
CA (1) CA2744756C (enExample)
IL (1) IL213216A0 (enExample)
MX (1) MX2011006541A (enExample)
PA (1) PA8855001A1 (enExample)
SG (1) SG171781A1 (enExample)
TW (1) TW201026696A (enExample)
UY (1) UY32336A (enExample)
WO (1) WO2010070523A1 (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2379546A1 (en) * 2008-12-19 2011-10-26 Pfizer Inc. Monocarbams
CA2815821C (en) * 2010-11-29 2015-07-07 Pfizer Inc. Monobactams useful for treating bacterial infections
UY34585A (es) 2012-01-24 2013-09-02 Aicuris Gmbh & Co Kg Compuestos b-lactámicos sustituidos con amidina, su preparación y uso
HRP20201423T1 (hr) * 2015-09-23 2020-12-11 Novartis Ag Soli i čvrsti oblici antibiotika monobaktam
CN105481812B (zh) * 2015-11-30 2020-04-21 重庆天奕恒化科技有限公司 一种5-苄氧基-4-氧代-4h-吡喃-2-羧酸的制备方法
KR20190092566A (ko) 2016-12-21 2019-08-07 아이쿠리스 게엠베하 운트 코. 카게 항생제 내성 박테리아 균주에 의한 감염을 위한 아미딘 치환된 β-락탐 화합물 및 β-락타마제 억제제를 사용하는 조합 요법
AU2018311521B2 (en) 2017-08-02 2022-03-03 Novartis Ag Process for preparing 1 -(((Z)-(1 -(2-aminothiazol-4-yl)-2-oxo-2-(((3S,4R)-2-oxo-4-((2-oxooxazolidin-3-y l)methyl)-1 -sulfoazetidin-3- yl)amino)ethylidene)amino)oxy)cyclopropane carboxylic acid
US11034648B2 (en) 2017-08-23 2021-06-15 Helmholtz-Zentrum Für Cystobactamide derivatives
AU2018325894B2 (en) 2017-08-31 2022-08-04 Hokko Chemical Industry Co., Ltd. 1-(N,N-disubstituted carbamoyl) 4-(substituted sulfonyl)triazolin-5-one derivatives, 4-(N,N-disubstituted carbamoyl) 1-(substituted sulfonyl)triazolin-5-one derivatives, and herbicide containing same as active ingredient
CN111511737B (zh) 2018-01-29 2022-10-18 南京明德新药研发有限公司 用于治疗细菌感染的单环β-内酰胺化合物
WO2020125670A1 (zh) 2018-12-18 2020-06-25 南京明德新药研发有限公司 单环β-内酰胺化合物在制药中的应用
EP4079305A4 (en) 2019-12-19 2024-01-10 Shenzhen Optimum Biological Technology Co., Ltd APPLICATION OF A COMPOUND IN THE PREPARATION OF DRUG

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NZ199981A (en) 1981-04-09 1985-08-16 Squibb & Sons Inc 2-oxo-1-(((substituted sulphonyl)amino)carbonyl)azetidines
US4587047A (en) * 1981-04-09 1986-05-06 E. R. Squibb & Sons, Inc. 2-oxo-1-[[(substituted sulfonyl)amino]-carbonyl]azetidines
US5006650A (en) * 1987-02-11 1991-04-09 The Upjohn Company Novel N-1 substituted beta-lactams as antibiotics
JPH02502378A (ja) 1987-02-11 1990-08-02 ジ・アップジョン・カンパニー 抗生物質としての新規なＮ‐１置換β‐ラクタム
JPH02502455A (ja) * 1987-02-27 1990-08-09 ジ・アップジョン・カンパニー ピリドンカルボン酸または酸誘導体を含有する抗生物質β‐ラクタム
CA1317298C (en) * 1987-03-03 1993-05-04 Upjohn Company (The) Antibiotic sulfonylaminocarbonyl activated .beta.-lactams
US4762922A (en) * 1987-07-01 1988-08-09 Squibb Corporation 2-oxo-1-[[(substituted sulfonyl)amino]-carbonyl]azetidines
US5015737A (en) * 1987-07-22 1991-05-14 The Upjohn Company Therapeutically useful beta-lactams
US4777252A (en) * 1987-08-13 1988-10-11 E. R. Squibb & Sons, Inc. 2-oxo-1-[[(substituted sulfonyl)amino]-carbonyl]azetidines
US4889930A (en) 1987-12-21 1989-12-26 E. R. Squibb & Sons, Inc. Process for making 2-oxo-1-((substituted sulfonyl)amino)carbonzyl)azetidines and intermediates used therein
JPH01305081A (ja) 1988-04-04 1989-12-08 E R Squibb & Sons Inc ３―アシルアミノ―１―［［［（置換スルホニル）アミノ〕カルボニル〕アミノ〕―２―アゼチジノン類
EP0344707A3 (en) 1988-06-02 1990-04-18 E.R. Squibb & Sons, Inc. 2-Oxo-1-[[(substituted sulfonyl)-amino]carbonyl]-azetidine derivatives
US4959470A (en) * 1988-08-17 1990-09-25 E. R. Squibb & Sons, Inc. 2-oxo-[[(substituted sulfonyl)-amino]carbonyl]-azetidines
AU4064089A (en) 1988-09-27 1990-04-18 Upjohn Company, The Dihydroxyaryl 4-substituted monocarbams as antibiotics
CA2210787A1 (en) 1997-07-17 1999-01-17 William R. Collier Self-contained work station
MX2009009918A (es) 2007-03-23 2009-10-19 Basilea Pharmaceutica Ag Medicamentos combinados para el tratamiento de infecciones bacterianas.
EP2379546A1 (en) * 2008-12-19 2011-10-26 Pfizer Inc. Monocarbams

Also Published As

Publication number Publication date
US8252782B2 (en) 2012-08-28
MX2011006541A (es) 2011-07-20
TW201026696A (en) 2010-07-16
US8324198B1 (en) 2012-12-04
AU2009329169A1 (en) 2010-06-24
IL213216A0 (en) 2011-07-31
PA8855001A1 (es) 2010-07-27
EP2379546A1 (en) 2011-10-26
AR074801A1 (es) 2011-02-16
AU2009329169B2 (en) 2012-06-28
CN102325769A (zh) 2012-01-18
CA2744756C (en) 2013-05-28
SG171781A1 (en) 2011-07-28
JP2012512863A (ja) 2012-06-07
WO2010070523A1 (en) 2010-06-24
US20120289455A1 (en) 2012-11-15
CA2744756A1 (en) 2010-06-24
KR20110086742A (ko) 2011-07-29
US20100160281A1 (en) 2010-06-24

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Effective date: 20190117