JP2007531726A5 - - Google Patents
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- Publication number
- JP2007531726A5 JP2007531726A5 JP2007506295A JP2007506295A JP2007531726A5 JP 2007531726 A5 JP2007531726 A5 JP 2007531726A5 JP 2007506295 A JP2007506295 A JP 2007506295A JP 2007506295 A JP2007506295 A JP 2007506295A JP 2007531726 A5 JP2007531726 A5 JP 2007531726A5
- Authority
- JP
- Japan
- Prior art keywords
- sodium
- polymer
- binding composition
- polyvinyl
- binding
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 229910052708 sodium Inorganic materials 0.000 claims 39
- 239000011734 sodium Substances 0.000 claims 39
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 claims 37
- 239000000203 mixture Substances 0.000 claims 28
- 229920000642 polymer Polymers 0.000 claims 25
- 229920002554 vinyl polymer Polymers 0.000 claims 14
- LNOPIUAQISRISI-UHFFFAOYSA-N n'-hydroxy-2-propan-2-ylsulfonylethanimidamide Chemical compound CC(C)S(=O)(=O)CC(N)=NO LNOPIUAQISRISI-UHFFFAOYSA-N 0.000 claims 6
- 229920001577 copolymer Polymers 0.000 claims 5
- 230000035699 permeability Effects 0.000 claims 4
- ZTWTYVWXUKTLCP-UHFFFAOYSA-N vinylphosphonic acid Chemical compound OP(O)(=O)C=C ZTWTYVWXUKTLCP-UHFFFAOYSA-N 0.000 claims 4
- 210000001035 gastrointestinal tract Anatomy 0.000 claims 3
- BDHFUVZGWQCTTF-UHFFFAOYSA-N sulfonic acid Chemical compound OS(=O)=O BDHFUVZGWQCTTF-UHFFFAOYSA-N 0.000 claims 3
- TYCFGHUTYSLISP-UHFFFAOYSA-N 2-fluoroprop-2-enoic acid Chemical compound OC(=O)C(F)=C TYCFGHUTYSLISP-UHFFFAOYSA-N 0.000 claims 2
- 229920002126 Acrylic acid copolymer Polymers 0.000 claims 2
- CERQOIWHTDAKMF-UHFFFAOYSA-M Methacrylate Chemical compound CC(=C)C([O-])=O CERQOIWHTDAKMF-UHFFFAOYSA-M 0.000 claims 2
- 229920002125 Sokalan® Polymers 0.000 claims 2
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 claims 2
- 239000002253 acid Substances 0.000 claims 2
- 150000001412 amines Chemical class 0.000 claims 2
- 238000005341 cation exchange Methods 0.000 claims 2
- 208000020832 chronic kidney disease Diseases 0.000 claims 2
- 229920006037 cross link polymer Polymers 0.000 claims 2
- 229910001415 sodium ion Inorganic materials 0.000 claims 2
- USDNTLSSMWDFHG-UHFFFAOYSA-N 2-ethenylpyridine;styrene Chemical compound C=CC1=CC=CC=C1.C=CC1=CC=CC=N1 USDNTLSSMWDFHG-UHFFFAOYSA-N 0.000 claims 1
- 239000005541 ACE inhibitor Substances 0.000 claims 1
- 102000008873 Angiotensin II receptor Human genes 0.000 claims 1
- 108050000824 Angiotensin II receptor Proteins 0.000 claims 1
- 206010007558 Cardiac failure chronic Diseases 0.000 claims 1
- 206010016803 Fluid overload Diseases 0.000 claims 1
- 206010020772 Hypertension Diseases 0.000 claims 1
- 241001465754 Metazoa Species 0.000 claims 1
- ABLZXFCXXLZCGV-UHFFFAOYSA-N Phosphorous acid Chemical compound OP(O)=O ABLZXFCXXLZCGV-UHFFFAOYSA-N 0.000 claims 1
- 230000002378 acidificating effect Effects 0.000 claims 1
- 239000002160 alpha blocker Substances 0.000 claims 1
- 229940044094 angiotensin-converting-enzyme inhibitor Drugs 0.000 claims 1
- 239000002876 beta blocker Substances 0.000 claims 1
- 229940097320 beta blocking agent Drugs 0.000 claims 1
- 208000022831 chronic renal failure syndrome Diseases 0.000 claims 1
- 208000019425 cirrhosis of liver Diseases 0.000 claims 1
- 230000007423 decrease Effects 0.000 claims 1
- 239000002934 diuretic Substances 0.000 claims 1
- 230000001882 diuretic effect Effects 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 208000028208 end stage renal disease Diseases 0.000 claims 1
- 201000000523 end stage renal failure Diseases 0.000 claims 1
- 238000001727 in vivo Methods 0.000 claims 1
- 230000010220 ion permeability Effects 0.000 claims 1
- 210000003750 lower gastrointestinal tract Anatomy 0.000 claims 1
- 210000004798 organs belonging to the digestive system Anatomy 0.000 claims 1
- 229920000172 poly(styrenesulfonic acid) Polymers 0.000 claims 1
- 229940005642 polystyrene sulfonic acid Drugs 0.000 claims 1
- 239000003087 receptor blocking agent Substances 0.000 claims 1
- 239000011347 resin Substances 0.000 claims 1
- 229920005989 resin Polymers 0.000 claims 1
- 210000002438 upper gastrointestinal tract Anatomy 0.000 claims 1
- CYEUYQMHSRMIQS-UHFFFAOYSA-N CCC(NC(C)(C)CS(O)(O)=O)=O Chemical compound CCC(NC(C)(C)CS(O)(O)=O)=O CYEUYQMHSRMIQS-UHFFFAOYSA-N 0.000 description 1
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/814,749 US8192758B2 (en) | 2004-03-30 | 2004-03-30 | Ion binding compositions |
| US10/813,872 | 2004-03-30 | ||
| US10/813,872 US8282960B2 (en) | 2004-03-30 | 2004-03-30 | Ion binding compositions |
| US10/814,527 US7854924B2 (en) | 2004-03-30 | 2004-03-30 | Methods and compositions for treatment of ion imbalances |
| US10/814,749 | 2004-03-30 | ||
| US10/814,527 | 2004-03-30 | ||
| US10/965,274 US7488495B2 (en) | 2004-03-30 | 2004-10-13 | Ion binding polymers and uses thereof |
| US10/965,274 | 2004-10-13 | ||
| PCT/US2005/011010 WO2005094384A2 (en) | 2004-03-30 | 2005-03-30 | Methods and compositions for treatment of ion imbalances |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2007531726A JP2007531726A (ja) | 2007-11-08 |
| JP2007531726A5 true JP2007531726A5 (enExample) | 2008-05-15 |
| JP5000480B2 JP5000480B2 (ja) | 2012-08-15 |
Family
ID=35054544
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007506518A Expired - Fee Related JP4964122B2 (ja) | 2004-03-30 | 2005-03-30 | イオン結合組成物 |
| JP2007506580A Expired - Lifetime JP4974882B2 (ja) | 2004-03-30 | 2005-03-30 | イオン結合ポリマーとその利用 |
| JP2007506295A Expired - Fee Related JP5000480B2 (ja) | 2004-03-30 | 2005-03-30 | イオンバランス異常の治療の方法および組成物 |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007506518A Expired - Fee Related JP4964122B2 (ja) | 2004-03-30 | 2005-03-30 | イオン結合組成物 |
| JP2007506580A Expired - Lifetime JP4974882B2 (ja) | 2004-03-30 | 2005-03-30 | イオン結合ポリマーとその利用 |
Country Status (12)
| Country | Link |
|---|---|
| US (14) | US7776319B2 (enExample) |
| EP (3) | EP1732523B9 (enExample) |
| JP (3) | JP4964122B2 (enExample) |
| KR (3) | KR101228233B1 (enExample) |
| AU (3) | AU2005231383B2 (enExample) |
| BR (3) | BRPI0509331B8 (enExample) |
| CA (3) | CA2558029C (enExample) |
| DE (1) | DE112005000730B4 (enExample) |
| GB (3) | GB2430367B (enExample) |
| MX (1) | MXPA06011270A (enExample) |
| PL (1) | PL1732523T3 (enExample) |
| WO (3) | WO2005097072A1 (enExample) |
Families Citing this family (47)
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| US7381428B2 (en) | 2003-08-26 | 2008-06-03 | Shire International Licensing B.V. | Stabilized lanthanum carbonate compositions |
| SI2172205T1 (sl) | 2003-08-26 | 2014-10-30 | Shire Biopharmaceuticals Holdings Ireland Limited | Farmacevtska formulacija obsegajoča lantanove spojine |
| EP2158902B1 (en) * | 2004-03-30 | 2017-12-06 | Relypsa, Inc. | Ion binding compositions and their use |
| KR101228233B1 (ko) * | 2004-03-30 | 2013-01-31 | 리립사, 인크. | 이온 결합 중합체 및 이의 용도 |
| DE112006002618T5 (de) * | 2005-09-30 | 2008-08-28 | Ilypsa Inc., Santa Clara | Verfahren und Zusammensetzungen zum selektiven Entfernen von Kaliumionen aus dem Gastrointestinaltrakt eines Säugers |
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| BRPI0616603A2 (pt) * | 2005-09-30 | 2012-12-25 | Ilypsa Inc | mÉtodo para preparar um compàsito de nécleo-envoltàrio, e para a manufatura de um medicamento, composiÇço farmacÊutica, e, uso da mesma |
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| JP6475624B2 (ja) * | 2012-10-08 | 2019-02-27 | レリプサ， インコーポレイテッド | 高血圧症及び高カリウム血症を治療するためのカリウム結合剤 |
| PT2882444T (pt) | 2012-10-22 | 2025-11-21 | Zs Pharma Inc | Silicato de zircónio microporoso para tratamento de hipercalemia |
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| US9675636B2 (en) * | 2014-01-31 | 2017-06-13 | University Of Kansas | Micelle sequestering polymers |
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-
2005
- 2005-03-30 KR KR1020067022589A patent/KR101228233B1/ko not_active Expired - Fee Related
- 2005-03-30 GB GB0621242A patent/GB2430367B/en not_active Expired - Lifetime
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- 2005-03-30 KR KR1020067022533A patent/KR101153035B1/ko not_active Expired - Fee Related
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- 2005-03-30 MX MXPA06011270A patent/MXPA06011270A/es active IP Right Grant
- 2005-03-30 GB GB0621244A patent/GB2430368B/en not_active Expired - Fee Related
- 2005-03-30 EP EP05731099A patent/EP1732516B1/en not_active Expired - Lifetime
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- 2005-03-30 AU AU2005231424A patent/AU2005231424B2/en active Active
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2008
- 2008-03-26 US US12/055,726 patent/US8216560B2/en active Active
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2012
- 2012-10-05 US US13/646,104 patent/US20130272990A1/en not_active Abandoned
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2014
- 2014-06-04 US US14/295,950 patent/US20140286891A1/en not_active Abandoned
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