PT2882444T - Silicato de zircónio microporoso para tratamento de hipercalemia - Google Patents

Silicato de zircónio microporoso para tratamento de hipercalemia

Info

Publication number
PT2882444T
PT2882444T PT138496518T PT13849651T PT2882444T PT 2882444 T PT2882444 T PT 2882444T PT 138496518 T PT138496518 T PT 138496518T PT 13849651 T PT13849651 T PT 13849651T PT 2882444 T PT2882444 T PT 2882444T
Authority
PT
Portugal
Prior art keywords
zirconium silicate
microporous zirconium
treating hyperkalemia
hyperkalemia
treating
Prior art date
Application number
PT138496518T
Other languages
English (en)
Original Assignee
Zs Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=50485556&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT2882444(T) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Zs Pharma Inc filed Critical Zs Pharma Inc
Publication of PT2882444T publication Critical patent/PT2882444T/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/143Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/12Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0006Controlling or regulating processes
    • B01J19/0013Controlling the temperature of the process
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0053Details of the reactor
    • B01J19/006Baffles
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/18Stationary reactors having moving elements inside
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J39/00Cation exchange; Use of material as cation exchangers; Treatment of material for improving the cation exchange properties
    • B01J39/02Processes using inorganic exchangers
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J39/00Cation exchange; Use of material as cation exchangers; Treatment of material for improving the cation exchange properties
    • B01J39/08Use of material as cation exchangers; Treatment of material for improving the cation exchange properties
    • B01J39/14Base exchange silicates, e.g. zeolites
    • CCHEMISTRY; METALLURGY
    • C01INORGANIC CHEMISTRY
    • C01BNON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
    • C01B33/00Silicon; Compounds thereof
    • C01B33/20Silicates
    • CCHEMISTRY; METALLURGY
    • C01INORGANIC CHEMISTRY
    • C01BNON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
    • C01B39/00Compounds having molecular sieve and base-exchange properties, e.g. crystalline zeolites; Their preparation; After-treatment, e.g. ion-exchange or dealumination
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02Silicon compounds
    • C07F7/025Silicon compounds without C-silicon linkages
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00049Controlling or regulating processes
    • B01J2219/00051Controlling the temperature
    • B01J2219/00054Controlling or regulating the heat exchange system
    • B01J2219/00056Controlling or regulating the heat exchange system involving measured parameters
    • B01J2219/00058Temperature measurement
    • B01J2219/00063Temperature measurement of the reactants
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00049Controlling or regulating processes
    • B01J2219/00051Controlling the temperature
    • B01J2219/00074Controlling the temperature by indirect heating or cooling employing heat exchange fluids
    • B01J2219/00087Controlling the temperature by indirect heating or cooling employing heat exchange fluids with heat exchange elements outside the reactor
    • B01J2219/00094Jackets
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00761Details of the reactor
    • B01J2219/00763Baffles
    • B01J2219/00765Baffles attached to the reactor wall
    • B01J2219/00768Baffles attached to the reactor wall vertical
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Inorganic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Geology (AREA)
  • General Life Sciences & Earth Sciences (AREA)
  • Materials Engineering (AREA)
  • Toxicology (AREA)
  • Endocrinology (AREA)
  • Rheumatology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Silicates, Zeolites, And Molecular Sieves (AREA)
  • Combustion & Propulsion (AREA)
PT138496518T 2012-10-22 2013-10-22 Silicato de zircónio microporoso para tratamento de hipercalemia PT2882444T (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261716956P 2012-10-22 2012-10-22
US201361800182P 2013-03-15 2013-03-15

Publications (1)

Publication Number Publication Date
PT2882444T true PT2882444T (pt) 2025-11-21

Family

ID=50485556

Family Applications (1)

Application Number Title Priority Date Filing Date
PT138496518T PT2882444T (pt) 2012-10-22 2013-10-22 Silicato de zircónio microporoso para tratamento de hipercalemia

Country Status (24)

Country Link
US (2) US8877255B2 (pt)
EP (1) EP2882444B1 (pt)
JP (1) JP6423795B2 (pt)
KR (1) KR102184602B1 (pt)
CN (1) CN104797263B (pt)
AR (1) AR093106A1 (pt)
AU (2) AU2013334776B2 (pt)
BR (1) BR112015008962B1 (pt)
CA (1) CA2891053C (pt)
CL (1) CL2015001014A1 (pt)
DK (1) DK2882444T3 (pt)
ES (1) ES3053035T3 (pt)
FI (1) FI2882444T3 (pt)
HR (1) HRP20251373T1 (pt)
IL (1) IL237905A (pt)
LT (1) LT2882444T (pt)
MX (1) MX360684B (pt)
PH (1) PH12015500849B1 (pt)
PT (1) PT2882444T (pt)
RS (1) RS67365B1 (pt)
SI (1) SI2882444T1 (pt)
SM (1) SMT202500409T1 (pt)
WO (1) WO2014066407A1 (pt)
ZA (1) ZA201502186B (pt)

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ATE496134T1 (de) 2002-03-29 2011-02-15 Xoma Technology Ltd Multigene vectoren und methoden für eine erhöhte expression von rekombinanten polypeptiden
HRP20190146T4 (hr) 2011-02-11 2025-11-07 Zs Pharma, Inc Uporaba cirkonijevog silikata za liječenje hiperkalemije
US9943637B2 (en) 2012-06-11 2018-04-17 ZS Pharma, Inc. Microporous zirconium silicate and its method of production
CN104968336A (zh) 2012-07-11 2015-10-07 Zs制药公司 用于治疗高钙血症患者高钾血症的微孔硅酸锆以及用于治疗高钾血症的改进的含钙组合物
PT2882444T (pt) 2012-10-22 2025-11-21 Zs Pharma Inc Silicato de zircónio microporoso para tratamento de hipercalemia
US10695365B2 (en) 2012-10-22 2020-06-30 ZS Pharma, Inc. Microporous zirconium silicate for the treatment of hyperkalemia
US20160051584A1 (en) * 2013-04-05 2016-02-25 ZS Pharma, Inc. Microporous zirconium silicate and diuretics for the reduction of potassium and treatment of chronic kidney and/or chronic heart disease
US20160038538A1 (en) * 2013-11-08 2016-02-11 ZS Pharma, Inc. Microporous zirconium silicate for the treatment of hyperkalemia
CA2929978C (en) * 2013-11-08 2021-11-30 ZS Pharma, Inc. Microporous zirconium silicate for the treatment of hyperkalemia
US9592253B1 (en) * 2015-10-14 2017-03-14 ZS Pharma, Inc. Extended use zirconium silicate compositions and methods of use thereof
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US12036528B2 (en) 2020-09-30 2024-07-16 Uop Llc Process for removing lead ions from boldily fluids using metallate ion exchange compositions
CN118439624B (zh) * 2024-04-15 2025-01-24 时森海(杭州)医药科技有限公司 一种锆硅酸钠水合物及其制备方法
CN119643609A (zh) * 2025-02-17 2025-03-18 北京华睿鼎信科技有限公司 一种晶相杂质的分析方法

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PT2882444T (pt) 2012-10-22 2025-11-21 Zs Pharma Inc Silicato de zircónio microporoso para tratamento de hipercalemia

Also Published As

Publication number Publication date
US20140113002A1 (en) 2014-04-24
PH12015500849B1 (en) 2017-09-06
MX360684B (es) 2018-11-13
PH12015500849A1 (en) 2015-06-22
JP6423795B2 (ja) 2018-11-14
CN104797263A (zh) 2015-07-22
MX2015005104A (es) 2015-07-17
US8877255B2 (en) 2014-11-04
IL237905A (en) 2017-12-31
EP2882444B1 (en) 2025-09-17
DK2882444T3 (da) 2025-11-03
WO2014066407A1 (en) 2014-05-01
AU2017251722A1 (en) 2017-11-09
CA2891053C (en) 2020-12-01
SI2882444T1 (sl) 2026-01-30
CN104797263B (zh) 2018-02-09
SMT202500409T1 (it) 2025-11-10
AU2013334776B2 (en) 2017-08-31
AU2013334776A1 (en) 2015-05-07
CA2891053A1 (en) 2014-05-01
LT2882444T (lt) 2025-11-10
BR112015008962B1 (pt) 2021-09-21
JP2016505510A (ja) 2016-02-25
EP2882444A1 (en) 2015-06-17
FI2882444T3 (fi) 2025-11-05
EP2882444A4 (en) 2016-03-02
ZA201502186B (en) 2016-01-27
BR112015008962A2 (pt) 2017-07-04
HRP20251373T1 (hr) 2025-12-19
KR102184602B1 (ko) 2020-11-30
AR093106A1 (es) 2015-05-20
HK1211494A1 (en) 2016-05-27
KR20150074053A (ko) 2015-07-01
RS67365B1 (sr) 2025-11-28
CL2015001014A1 (es) 2015-08-28
US9913860B2 (en) 2018-03-13
ES3053035T3 (en) 2026-01-16
US20150250821A1 (en) 2015-09-10

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