JP2007507532A5 - - Google Patents
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- JP2007507532A5 JP2007507532A5 JP2006534173A JP2006534173A JP2007507532A5 JP 2007507532 A5 JP2007507532 A5 JP 2007507532A5 JP 2006534173 A JP2006534173 A JP 2006534173A JP 2006534173 A JP2006534173 A JP 2006534173A JP 2007507532 A5 JP2007507532 A5 JP 2007507532A5
- Authority
- JP
- Japan
- Prior art keywords
- international
- opioid receptor
- documents cited
- peptidic
- pamphlet
- Prior art date
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Description
多数の非ペプチド性δオピオイド受容体調節因子が存在するが、望ましくない副作用を最小限にし、有益な薬学的特性を提供するような方法で使用される選択的δオピオイド受容体活性を有する化合物に対する要求は満たされていない。本発明は、他の重要な目的と共に、これらを実現するものである。
この出願の発明に関連する先行技術文献情報としては、以下のものがある(国際出願日以降国際段階で引用された文献及び他国に国内移行した際に引用された文献を含む)。
米国特許6,645,973号明細書
国際公開第94/17045号パンフレット
この出願の発明に関連する先行技術文献情報としては、以下のものがある(国際出願日以降国際段階で引用された文献及び他国に国内移行した際に引用された文献を含む)。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US50786403P | 2003-10-01 | 2003-10-01 | |
US60/507,864 | 2003-10-01 | ||
PCT/US2004/032479 WO2005033073A2 (en) | 2003-10-01 | 2004-10-01 | Spirocyclic heterocyclic derivatives and methods of their use |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2011107724A Division JP2011201896A (ja) | 2003-10-01 | 2011-05-13 | スピロ環複素環誘導体及びそれらを使用する方法 |
Publications (3)
Publication Number | Publication Date |
---|---|
JP2007507532A JP2007507532A (ja) | 2007-03-29 |
JP2007507532A5 true JP2007507532A5 (ja) | 2007-11-22 |
JP4976134B2 JP4976134B2 (ja) | 2012-07-18 |
Family
ID=34421676
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2006534173A Expired - Fee Related JP4976134B2 (ja) | 2003-10-01 | 2004-10-01 | スピロ環複素環誘導体及びそれらを使用する方法 |
JP2011107724A Pending JP2011201896A (ja) | 2003-10-01 | 2011-05-13 | スピロ環複素環誘導体及びそれらを使用する方法 |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2011107724A Pending JP2011201896A (ja) | 2003-10-01 | 2011-05-13 | スピロ環複素環誘導体及びそれらを使用する方法 |
Country Status (13)
Country | Link |
---|---|
US (6) | US7338962B2 (ja) |
EP (1) | EP1675847B1 (ja) |
JP (2) | JP4976134B2 (ja) |
KR (2) | KR101255074B1 (ja) |
CN (2) | CN100549004C (ja) |
AU (1) | AU2004278414B2 (ja) |
BR (1) | BRPI0415165A (ja) |
CA (1) | CA2541014A1 (ja) |
CO (1) | CO5690640A2 (ja) |
IL (2) | IL174702A (ja) |
NZ (3) | NZ546834A (ja) |
WO (1) | WO2005033073A2 (ja) |
ZA (1) | ZA200603414B (ja) |
Families Citing this family (40)
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JP4976134B2 (ja) * | 2003-10-01 | 2012-07-18 | アドラー コーポレーション | スピロ環複素環誘導体及びそれらを使用する方法 |
US7598261B2 (en) * | 2005-03-31 | 2009-10-06 | Adolor Corporation | Spirocyclic heterocyclic derivatives and methods of their use |
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US7576207B2 (en) * | 2006-04-06 | 2009-08-18 | Adolor Corporation | Spirocyclic heterocyclic derivatives and methods of their use |
CA2648831A1 (en) * | 2006-05-05 | 2007-11-15 | Ulrich Reiser | Spiro- (tho) benzopyran-2, 4' -piperidine-and cyclohexane derivatives as inhibitors of specific cell cycle enzymes |
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TWI425945B (zh) * | 2007-05-28 | 2014-02-11 | Seldar Pharma Inc | 四氫異喹啉-1-酮衍生物或其鹽 |
WO2009097567A1 (en) * | 2008-01-30 | 2009-08-06 | Cephalon, Inc. | Substituted spirocyclic piperidine derivatives as histamine-3 (h3) receptor ligands |
NZ587034A (en) * | 2008-01-30 | 2011-12-22 | Cephalon Inc | Substituted spirocyclic piperidine derivatives as histamine-3 (H3) receptor ligands |
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SI2670752T1 (sl) | 2011-02-02 | 2016-10-28 | Vertex Pharmaceuticals Incorporated | Pirolopirazin-spirociklični piperidin amidi kot modulatorji ionskih kanalčkov |
EP2675812B1 (en) * | 2011-02-18 | 2017-08-30 | Vertex Pharmaceuticals Incorporated | Chroman - spirocyclic piperidine amides as modulators of ion channels |
AU2012229187B2 (en) | 2011-03-14 | 2016-11-10 | Vertex Pharmaceuticals Incorporated | Morpholine-spirocyclic piperidine amides as modulators of ion channels |
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AU2013302468B2 (en) | 2012-08-16 | 2017-08-24 | Janssen Pharmaceutica Nv | Substituted pyrazoles as N-type calcium channel blockers |
ES2926662T3 (es) | 2012-08-21 | 2022-10-27 | Janssen Pharmaceutica Nv | Anticuerpos contra haptenos de risperidona y uso de los mismos |
WO2014031656A1 (en) | 2012-08-21 | 2014-02-27 | Ortho-Clinical Diagnostics, Inc | Antibodies to olanzapine haptens and use thereof |
AU2013305907B2 (en) | 2012-08-21 | 2018-01-18 | Saladax Biomedical Inc. | Antibodies to quetiapine and use thereof |
US9504682B2 (en) | 2012-08-21 | 2016-11-29 | Janssen Pharmaceutica Nv | Haptens of aripiprazole |
ES2691092T3 (es) | 2012-08-21 | 2018-11-23 | Janssen Pharmaceutica Nv | Anticuerpos contra la risperidona y uso de los mismos |
CN104736567B (zh) | 2012-08-21 | 2019-09-03 | 詹森药业有限公司 | 阿立哌唑半抗原的抗体及其用途 |
EP3354751B1 (en) | 2012-08-21 | 2019-10-02 | Janssen Pharmaceutica NV | Antibodies to aripiprazole and use thereof |
JP2015529199A (ja) | 2012-08-21 | 2015-10-05 | オルソ−クリニカル ダイアグノスティクス,インコーポレイティド | パリペリドンハプテンに対する抗体及びその使用 |
PL2888286T3 (pl) | 2012-08-21 | 2018-07-31 | Janssen Pharmaceutica Nv | Przeciwciała skierowane przeciwko haptenom kwetiapinowym i ich zastosowanie |
PT2888590T (pt) | 2012-08-21 | 2020-09-11 | Janssen Pharmaceutica Nv | Anticorpos para olanzapina e utilização destes |
CN108640996A (zh) | 2012-08-21 | 2018-10-12 | 詹森药业有限公司 | 帕潘立酮的抗体及其用途 |
JP6141444B2 (ja) | 2012-12-14 | 2017-06-07 | パーデュー、ファーマ、リミテッド、パートナーシップ | スピロ環式モルフィナンおよびこれらの使用 |
ES2653265T3 (es) | 2012-12-28 | 2018-02-06 | Purdue Pharma Lp | Morfinanos sustituidos y el uso de éstos |
SG11201600846WA (en) * | 2013-08-16 | 2016-03-30 | Janssen Pharmaceutica Nv | Substituted imidazoles as n-type calcium channel blockers |
US9453002B2 (en) | 2013-08-16 | 2016-09-27 | Janssen Pharmaceutica Nv | Substituted imidazoles as N-type calcium channel blockers |
US9299409B2 (en) * | 2013-09-11 | 2016-03-29 | Tadashi Miyakawa | Semiconductor storage device |
US9340542B2 (en) | 2013-12-26 | 2016-05-17 | Purdue Pharma L.P. | Propellane-based compounds and the use thereof |
EP3233799B1 (en) | 2014-12-19 | 2021-05-19 | The Broad Institute, Inc. | Dopamine d2 receptor ligands |
WO2016100940A1 (en) | 2014-12-19 | 2016-06-23 | The Broad Institute, Inc. | Dopamine d2 receptor ligands |
KR20170025848A (ko) | 2015-08-31 | 2017-03-08 | 한국건설생활환경시험연구원 | 교류 직결형 엘이디 램프 결합 구조 |
US10588889B2 (en) | 2015-12-14 | 2020-03-17 | Trevena, Inc. | Methods of treating hyperalgesia |
MA44067A (fr) | 2015-12-17 | 2018-10-24 | Janssen Pharmaceutica Nv | Anticorps dirigés contre la quétiapine et utilisation associée |
EP3390449A1 (en) | 2015-12-17 | 2018-10-24 | Janssen Pharmaceutica N.V. | Antibodies to risperidone and use thereof |
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JP4976134B2 (ja) * | 2003-10-01 | 2012-07-18 | アドラー コーポレーション | スピロ環複素環誘導体及びそれらを使用する方法 |
US7598261B2 (en) * | 2005-03-31 | 2009-10-06 | Adolor Corporation | Spirocyclic heterocyclic derivatives and methods of their use |
US7576207B2 (en) * | 2006-04-06 | 2009-08-18 | Adolor Corporation | Spirocyclic heterocyclic derivatives and methods of their use |
CN101534819A (zh) * | 2006-09-12 | 2009-09-16 | 阿得罗公司 | 含氮的螺环化合物用于增强认知功能的应用 |
-
2004
- 2004-10-01 JP JP2006534173A patent/JP4976134B2/ja not_active Expired - Fee Related
- 2004-10-01 KR KR1020067008451A patent/KR101255074B1/ko not_active IP Right Cessation
- 2004-10-01 NZ NZ546834A patent/NZ546834A/en not_active IP Right Cessation
- 2004-10-01 CN CNB2004800356909A patent/CN100549004C/zh not_active Expired - Fee Related
- 2004-10-01 KR KR1020127001970A patent/KR20140015122A/ko active IP Right Grant
- 2004-10-01 NZ NZ593444A patent/NZ593444A/xx not_active IP Right Cessation
- 2004-10-01 US US10/957,554 patent/US7338962B2/en not_active Expired - Fee Related
- 2004-10-01 AU AU2004278414A patent/AU2004278414B2/en not_active Ceased
- 2004-10-01 CA CA002541014A patent/CA2541014A1/en not_active Abandoned
- 2004-10-01 CN CN2009101634060A patent/CN101921279A/zh active Pending
- 2004-10-01 EP EP04817130A patent/EP1675847B1/en active Active
- 2004-10-01 WO PCT/US2004/032479 patent/WO2005033073A2/en active Application Filing
- 2004-10-01 BR BRPI0415165-8A patent/BRPI0415165A/pt not_active IP Right Cessation
-
2006
- 2006-03-30 IL IL174702A patent/IL174702A/en not_active IP Right Cessation
- 2006-04-21 CO CO06037980A patent/CO5690640A2/es not_active Application Discontinuation
- 2006-04-28 ZA ZA200603414A patent/ZA200603414B/en unknown
-
2007
- 2007-12-20 US US11/960,845 patent/US7638527B2/en not_active Expired - Fee Related
-
2009
- 2009-06-12 US US12/483,781 patent/US7906646B2/en not_active Expired - Fee Related
-
2010
- 2010-02-19 NZ NZ583451A patent/NZ583451A/en not_active IP Right Cessation
- 2010-03-05 US US12/718,439 patent/US8071611B2/en not_active Expired - Fee Related
- 2010-05-26 US US12/787,906 patent/US20100280058A1/en not_active Abandoned
- 2010-09-19 IL IL208249A patent/IL208249A/en not_active IP Right Cessation
-
2011
- 2011-05-13 JP JP2011107724A patent/JP2011201896A/ja active Pending
- 2011-10-17 US US13/274,616 patent/US20120165356A1/en not_active Abandoned
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