IT1307327B1 - Derivati idroisochinolinici sostituiti - Google Patents
Derivati idroisochinolinici sostituitiInfo
- Publication number
- IT1307327B1 IT1307327B1 IT1995MI001900A ITMI951900A IT1307327B1 IT 1307327 B1 IT1307327 B1 IT 1307327B1 IT 1995MI001900 A IT1995MI001900 A IT 1995MI001900A IT MI951900 A ITMI951900 A IT MI951900A IT 1307327 B1 IT1307327 B1 IT 1307327B1
- Authority
- IT
- Italy
- Prior art keywords
- hydroisokinolinic
- derivatives
- replaced
- replaced hydroisokinolinic
- hydroisokinolinic derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
- C07D217/04—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/14—Decongestants or antiallergics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
- C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
- C07D217/16—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals substituted by oxygen atoms
Priority Applications (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT1995MI001900A IT1307327B1 (it) | 1995-09-12 | 1995-09-12 | Derivati idroisochinolinici sostituiti |
| EP96932527A EP0854868A1 (en) | 1995-09-12 | 1996-09-12 | Substituted hydroisoquinoline derivatives and their use as pharmaceuticals |
| PCT/EP1996/004036 WO1997010216A1 (en) | 1995-09-12 | 1996-09-12 | Substituted hydroisoquinoline derivatives and their use as pharmaceuticals |
| JP9511672A JPH11512415A (ja) | 1995-09-12 | 1996-09-12 | 置換されたヒドロイソキノリン誘導体および医薬としてのその使用 |
| US09/029,621 US5968949A (en) | 1995-09-12 | 1996-09-12 | Substituted hydroisoquinoline derivatives and their use as pharmaceuticals |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT1995MI001900A IT1307327B1 (it) | 1995-09-12 | 1995-09-12 | Derivati idroisochinolinici sostituiti |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| ITMI951900A0 ITMI951900A0 (it) | 1995-09-12 |
| ITMI951900A1 ITMI951900A1 (it) | 1997-03-12 |
| IT1307327B1 true IT1307327B1 (it) | 2001-10-30 |
Family
ID=11372234
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT1995MI001900A IT1307327B1 (it) | 1995-09-12 | 1995-09-12 | Derivati idroisochinolinici sostituiti |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US5968949A (it) |
| EP (1) | EP0854868A1 (it) |
| JP (1) | JPH11512415A (it) |
| IT (1) | IT1307327B1 (it) |
| WO (1) | WO1997010216A1 (it) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2264928A1 (en) * | 1997-07-09 | 1999-01-21 | Koji Kawai | Antitussives |
| US6103722A (en) * | 1997-07-23 | 2000-08-15 | The Medical College Of Wisconsin Research Foundation Inc. | Ischemic preconditioning |
| AU756983B2 (en) * | 1998-03-10 | 2003-01-30 | Research Triangle Institute | Novel opiate compounds, methods of making and methods of use |
| US7282508B2 (en) | 2001-10-15 | 2007-10-16 | Janssen Pharmaceutica N.V. | Substituted 4-phenyl-4-(1H-imidazol-2-yl)-piperidine derivatives and their use as selective non-peptide delta opioid agonists |
| KR20140015122A (ko) | 2003-10-01 | 2014-02-06 | 아돌로 코포레이션 | 스피로시클릭 헤테로시클릭 유도체 및 이의 사용 방법 |
| US7598261B2 (en) | 2005-03-31 | 2009-10-06 | Adolor Corporation | Spirocyclic heterocyclic derivatives and methods of their use |
| US7476679B2 (en) | 2005-07-26 | 2009-01-13 | Research Triangle Institute | Octahydroisoquinoline compounds as opioid receptor modulators |
| US7576207B2 (en) | 2006-04-06 | 2009-08-18 | Adolor Corporation | Spirocyclic heterocyclic derivatives and methods of their use |
| US20080119452A1 (en) | 2006-09-12 | 2008-05-22 | Dolle Roland E | Methods for enhancing cognitive function |
| EA019833B1 (ru) | 2007-01-22 | 2014-06-30 | ДЖиТиЭкс, ИНК. | Вещества, связывающие ядерные рецепторы |
| US9604931B2 (en) | 2007-01-22 | 2017-03-28 | Gtx, Inc. | Nuclear receptor binding agents |
| US9623021B2 (en) * | 2007-01-22 | 2017-04-18 | Gtx, Inc. | Nuclear receptor binding agents |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2351599A1 (de) * | 1972-07-20 | 1974-01-31 | Du Pont | 4a-aryl-trans-decahydrochinoline und verfahren zu ihrer herstellung |
| SE7509022L (sv) * | 1974-09-09 | 1976-03-10 | Du Pont | Foreningar med analgetisk verkan |
| US4077954A (en) * | 1976-02-10 | 1978-03-07 | E. I. Du Pont De Nemours And Company | N-(p-methylphenethyl)-4a-aryl-trans-decahydroisoquinolines |
-
1995
- 1995-09-12 IT IT1995MI001900A patent/IT1307327B1/it active
-
1996
- 1996-09-12 EP EP96932527A patent/EP0854868A1/en not_active Withdrawn
- 1996-09-12 US US09/029,621 patent/US5968949A/en not_active Expired - Fee Related
- 1996-09-12 WO PCT/EP1996/004036 patent/WO1997010216A1/en not_active Application Discontinuation
- 1996-09-12 JP JP9511672A patent/JPH11512415A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| ITMI951900A0 (it) | 1995-09-12 |
| WO1997010216A1 (en) | 1997-03-20 |
| EP0854868A1 (en) | 1998-07-29 |
| ITMI951900A1 (it) | 1997-03-12 |
| US5968949A (en) | 1999-10-19 |
| JPH11512415A (ja) | 1999-10-26 |
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