JP2006522750A - 代謝性症候群ならびに関連の疾患および障害を治療するために、11β−ヒドロキシステロイドデヒドロゲナーゼ1型阻害剤および抗高血圧剤を使用する併用療法 - Google Patents
代謝性症候群ならびに関連の疾患および障害を治療するために、11β−ヒドロキシステロイドデヒドロゲナーゼ1型阻害剤および抗高血圧剤を使用する併用療法 Download PDFInfo
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- JP2006522750A JP2006522750A JP2006504357A JP2006504357A JP2006522750A JP 2006522750 A JP2006522750 A JP 2006522750A JP 2006504357 A JP2006504357 A JP 2006504357A JP 2006504357 A JP2006504357 A JP 2006504357A JP 2006522750 A JP2006522750 A JP 2006522750A
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- phenyl
- alkyl
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- methanone
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- 0 *C(c1c(*)c(*)c(*)c(*)c11)=C[N+]1[I-] Chemical compound *C(c1c(*)c(*)c(*)c(*)c11)=C[N+]1[I-] 0.000 description 3
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PCT/DK2004/000254 WO2004089416A2 (fr) | 2003-04-11 | 2004-04-06 | Polytherapie utilisant un inhibiteur de type 1 de la 11beta-hydroxysteroide deshydrogenase et un agent hypotenseur dans le traitement du syndrome metabolique et des troubles et maladies associes |
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JP2010513337A (ja) * | 2006-12-21 | 2010-04-30 | メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング | 選択的11β−HSD1阻害剤としての2−アダマンチル−ブチルアミド誘導体 |
WO2008078725A1 (fr) * | 2006-12-26 | 2008-07-03 | Daiichi Sankyo Company, Limited | Dérivé de thiazépine |
JP2011510046A (ja) * | 2008-01-25 | 2011-03-31 | ロディア オペレーションズ | エステルアミドの溶剤としての使用、新規のエステルアミド及びエステルアミドの製造方法 |
JP2015155410A (ja) * | 2008-10-28 | 2015-08-27 | ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー | アルデヒドデヒドロゲナーゼのモジュレーターおよびその使用方法 |
JP2016512825A (ja) * | 2013-03-15 | 2016-05-09 | シファ・バイオメディカル・コーポレイションShifa Biomedical Corporation | 抗プロタンパク質転換酵素サブチリシン/ケキシン9型(抗pcsk9)化合物および心血管疾患の治療および/または予防におけるその使用方法 |
JP2019031522A (ja) * | 2013-03-15 | 2019-02-28 | シファ・バイオメディカル・コーポレイションShifa Biomedical Corporation | 抗プロタンパク質転換酵素サブチリシン/ケキシン9型(抗pcsk9)化合物および心血管疾患の治療および/または予防におけるその使用方法 |
US11690847B2 (en) | 2016-11-30 | 2023-07-04 | Case Western Reserve University | Combinations of 15-PGDH inhibitors with corticosteroids and/or TNF inhibitors and uses thereof |
JP2020514323A (ja) * | 2017-02-06 | 2020-05-21 | ケース ウエスタン リザーブ ユニバーシティ | 短鎖デヒドロゲナーゼ活性を調節する組成物と方法 |
US11718589B2 (en) | 2017-02-06 | 2023-08-08 | Case Western Reserve University | Compositions and methods of modulating short-chain dehydrogenase |
JP2022524290A (ja) * | 2019-01-31 | 2022-05-02 | 杏林製薬株式会社 | 15-pgdh阻害薬 |
Also Published As
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WO2004089416A3 (fr) | 2005-03-03 |
WO2004089416A2 (fr) | 2004-10-21 |
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