WO2004089416A3 - Polytherapie utilisant un inhibiteur de type 1 de la 11beta-hydroxysteroide deshydrogenase et un agent hypotenseur dans le traitement du syndrome metabolique et des troubles et maladies associes - Google Patents

Polytherapie utilisant un inhibiteur de type 1 de la 11beta-hydroxysteroide deshydrogenase et un agent hypotenseur dans le traitement du syndrome metabolique et des troubles et maladies associes Download PDF

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Publication number
WO2004089416A3
WO2004089416A3 PCT/DK2004/000254 DK2004000254W WO2004089416A3 WO 2004089416 A3 WO2004089416 A3 WO 2004089416A3 DK 2004000254 W DK2004000254 W DK 2004000254W WO 2004089416 A3 WO2004089416 A3 WO 2004089416A3
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WIPO (PCT)
Prior art keywords
inhibitor
hydroxysteroid dehydrogenase
antihypertensive agent
11beta
combination
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PCT/DK2004/000254
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English (en)
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WO2004089416A2 (fr
Inventor
Gita Camilla Tejlgaard Kampen
Henrik Sune Andersen
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Novo Nordisk As
Gita Camilla Tejlgaard Kampen
Henrik Sune Andersen
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Application filed by Novo Nordisk As, Gita Camilla Tejlgaard Kampen, Henrik Sune Andersen filed Critical Novo Nordisk As
Priority to JP2006504357A priority Critical patent/JP2006522750A/ja
Priority to EP04725887A priority patent/EP1615666A2/fr
Publication of WO2004089416A2 publication Critical patent/WO2004089416A2/fr
Publication of WO2004089416A3 publication Critical patent/WO2004089416A3/fr
Priority to US11/254,125 priority patent/US7501405B2/en
Priority to US12/363,056 priority patent/US20090137574A1/en

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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
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Abstract

L'invention concerne une polythérapie consistant à administrer un inhibiteur de type 1 de la 11ß-hydroxystéroïde déshydrogénase et un agent hypotenseur utiles dans le traitement, la prévention et la réduction du risque de la résistance à l'insuline, la dyslipidémie, l'obésité, l'hypertension et d'autres troubles et maladies associés.
PCT/DK2004/000254 2003-04-11 2004-04-06 Polytherapie utilisant un inhibiteur de type 1 de la 11beta-hydroxysteroide deshydrogenase et un agent hypotenseur dans le traitement du syndrome metabolique et des troubles et maladies associes WO2004089416A2 (fr)

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US11/254,125 US7501405B2 (en) 2003-04-11 2005-10-11 Combination therapy using an 11β-hydroxysteroid dehydrogenase type 1 inhibitor and an antihypertensive agent for the treatment of metabolic syndrome and related diseases and disorders
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