JP2006522750A5 - - Google Patents

Info

Publication number

JP2006522750A5

JP2006522750A5 JP2006504357A JP2006504357A JP2006522750A5 JP 2006522750 A5 JP2006522750 A5 JP 2006522750A5 JP 2006504357 A JP2006504357 A JP 2006504357A JP 2006504357 A JP2006504357 A JP 2006504357A JP 2006522750 A5 JP2006522750 A5 JP 2006522750A5

Authority

JP

Japan

Prior art keywords

phenyl

alkyl

aryl

methyl

methanone

Prior art date

2004-04-06

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Pending

Links

• Espacenet
• Global Dossier
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• 125000000217 alkyl group Chemical group 0.000 claims 699
• 125000003118 aryl group Chemical group 0.000 claims 499
• 125000001072 heteroaryl group Chemical group 0.000 claims 342
• 125000003545 alkoxy group Chemical group 0.000 claims 305
• 125000000753 cycloalkyl group Chemical group 0.000 claims 196
• -1 hetcycloalkyl Chemical group 0.000 claims 175
• 239000000203 mixture Substances 0.000 claims 156
• 125000005157 alkyl carboxy group Chemical group 0.000 claims 123
• 229910052739 hydrogen Inorganic materials 0.000 claims 122
• 239000001257 hydrogen Substances 0.000 claims 122
• 150000002431 hydrogen Chemical class 0.000 claims 113
• 125000005129 aryl carbonyl group Chemical group 0.000 claims 108
• 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 88
• 125000004122 cyclic group Chemical group 0.000 claims 87
• 125000004043 oxo group Chemical group O=* 0.000 claims 81
• IJGRMHOSHXDMSA-UHFFFAOYSA-N nitrogen Substances N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims 78
• 229910052757 nitrogen Inorganic materials 0.000 claims 77
• QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen group Chemical group [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 claims 76
• 230000003287 optical Effects 0.000 claims 71
• 125000004916 (C1-C6) alkylcarbonyl group Chemical group 0.000 claims 65
• 125000004093 cyano group Chemical group *C#N 0.000 claims 65
• 125000005843 halogen group Chemical group 0.000 claims 63
• 239000003112 inhibitor Substances 0.000 claims 53
• 230000002401 inhibitory effect Effects 0.000 claims 53
• 229910052760 oxygen Inorganic materials 0.000 claims 50
• 125000004432 carbon atoms Chemical group C* 0.000 claims 49
• XEEYBQQBJWHFJM-UHFFFAOYSA-N iron Chemical group [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 claims 48
• 125000004104 aryloxy group Chemical group 0.000 claims 47
• 239000001301 oxygen Chemical group 0.000 claims 46
• MYMOFIZGZYHOMD-UHFFFAOYSA-N oxygen Chemical group O=O MYMOFIZGZYHOMD-UHFFFAOYSA-N 0.000 claims 46
• 125000004953 trihalomethyl group Chemical group 0.000 claims 44
• NINIDFKCEFEMDL-UHFFFAOYSA-N sulfur Chemical group [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 claims 43
• 102000008645 11-beta-Hydroxysteroid Dehydrogenase Type 1 Human genes 0.000 claims 42
• 108010088011 11-beta-Hydroxysteroid Dehydrogenase Type 1 Proteins 0.000 claims 42
• 229910052717 sulfur Chemical group 0.000 claims 42
• 125000005842 heteroatoms Chemical group 0.000 claims 41
• 239000011593 sulfur Chemical group 0.000 claims 38
• 125000002619 bicyclic group Chemical group 0.000 claims 37
• 239000002253 acid Substances 0.000 claims 36
• 150000003839 salts Chemical class 0.000 claims 36
• 239000011780 sodium chloride Substances 0.000 claims 36
• 125000005418 aryl aryl group Chemical group 0.000 claims 33
• 150000001875 compounds Chemical group 0.000 claims 33
• 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 claims 31
• 239000000556 agonist Substances 0.000 claims 30
• 230000003042 antagnostic Effects 0.000 claims 30
• 239000005557 antagonist Substances 0.000 claims 30
• 125000003710 aryl alkyl group Chemical group 0.000 claims 25
• VYFYYTLLBUKUHU-UHFFFAOYSA-N dopamine Chemical compound NCCC1=CC=C(O)C(O)=C1 VYFYYTLLBUKUHU-UHFFFAOYSA-N 0.000 claims 24
• 125000004951 trihalomethoxy group Chemical group 0.000 claims 23
• 239000002220 antihypertensive agent Substances 0.000 claims 17
• 125000000882 C2-C6 alkenyl group Chemical group 0.000 claims 14
• 125000003601 C2-C6 alkynyl group Chemical group 0.000 claims 13
• 102000002045 Endothelin Human genes 0.000 claims 12
• 108050009340 Endothelin Proteins 0.000 claims 12
• ZUBDGKVDJUIMQQ-UBFCDGJISA-N Endothelin-1 Chemical compound C([C@@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(O)=O)NC(=O)[C@H]1NC(=O)[C@H](CC=2C=CC=CC=2)NC(=O)[C@@H](CC=2C=CC(O)=CC=2)NC(=O)[C@H](C(C)C)NC(=O)[C@H]2CSSC[C@@H](C(N[C@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@H](CC(C)C)C(=O)N[C@@H](CCSC)C(=O)N[C@H](CC(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(O)=O)C(=O)N2)=O)NC(=O)[C@@H](CO)NC(=O)[C@H](N)CSSC1)C1=CNC=N1 ZUBDGKVDJUIMQQ-UBFCDGJISA-N 0.000 claims 12
• 102000004270 Peptidyl-Dipeptidase A Human genes 0.000 claims 12
• 108090000882 Peptidyl-Dipeptidase A Proteins 0.000 claims 12
• KBZOIRJILGZLEJ-LGYYRGKSSA-N argipressin Chemical compound C([C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CSSC[C@@H](C(N[C@@H](CC=2C=CC(O)=CC=2)C(=O)N1)=O)N)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)NCC(N)=O)C1=CC=CC=C1 KBZOIRJILGZLEJ-LGYYRGKSSA-N 0.000 claims 12
• 229960003638 dopamine Drugs 0.000 claims 12
• MWUXSHHQAYIFBG-UHFFFAOYSA-N nitric oxide Chemical compound O=[N] MWUXSHHQAYIFBG-UHFFFAOYSA-N 0.000 claims 12
• 229960003726 vasopressin Drugs 0.000 claims 12
• 125000002877 alkyl aryl group Chemical group 0.000 claims 11
• 125000005024 alkenyl aryl group Chemical group 0.000 claims 10
• 125000003342 alkenyl group Chemical group 0.000 claims 9
• 125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 claims 9
• UFHFLCQGNIYNRP-UHFFFAOYSA-N hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 9
• 125000003806 alkyl carbonyl amino group Chemical group 0.000 claims 8
• 125000000304 alkynyl group Chemical group 0.000 claims 8
• 125000005025 alkynylaryl group Chemical group 0.000 claims 8
• 125000005110 aryl thio group Chemical group 0.000 claims 8
• HMJIYCCIJYRONP-UHFFFAOYSA-N (+-)-Isradipine Chemical compound COC(=O)C1=C(C)NC(C)=C(C(=O)OC(C)C)C1C1=CC=CC2=NON=C12 HMJIYCCIJYRONP-UHFFFAOYSA-N 0.000 claims 6
• KOHIRBRYDXPAMZ-YHBROIRLSA-N (1R,1'R)-2,2'-iminobis{1-[(2R,2'S)-6-fluoro-3,4-dihydro-2H-chromen-2-yl]ethanol} Chemical compound C1CC2=CC(F)=CC=C2O[C@H]1[C@H](O)CNC[C@@H](O)[C@H]1OC2=CC=C(F)C=C2CC1 KOHIRBRYDXPAMZ-YHBROIRLSA-N 0.000 claims 6
• BIDNLKIUORFRQP-XYGFDPSESA-N (2S,4S)-4-cyclohexyl-1-[2-[[(1S)-2-methyl-1-propanoyloxypropoxy]-(4-phenylbutyl)phosphoryl]acetyl]pyrrolidine-2-carboxylic acid Chemical compound C([P@@](=O)(O[C@H](OC(=O)CC)C(C)C)CC(=O)N1[C@@H](C[C@H](C1)C1CCCCC1)C(O)=O)CCCC1=CC=CC=C1 BIDNLKIUORFRQP-XYGFDPSESA-N 0.000 claims 6
• AEAPORIZZWBIEX-DTBDINHYSA-N (3S,5R,8R,9S,10S,13S,14S,17S)-17-(furan-3-yl)-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,15,16-dodecahydro-1H-cyclopenta[a]phenanthrene-3,14,17-triol Chemical compound C=1([C@@]2(O)CC[C@]3(O)[C@H]4[C@@H]([C@]5(CC[C@H](O)C[C@H]5CC4)C)CC[C@@]32C)C=COC=1 AEAPORIZZWBIEX-DTBDINHYSA-N 0.000 claims 6
• 125000006700 (C1-C6) alkylthio group Chemical group 0.000 claims 6
• RZPZLFIUFMNCLY-WLHGVMLRSA-N (E)-but-2-enedioic acid;1-(propan-2-ylamino)-3-[4-(2-propan-2-yloxyethoxymethyl)phenoxy]propan-2-ol Chemical compound OC(=O)\C=C\C(O)=O.CC(C)NCC(O)COC1=CC=C(COCCOC(C)C)C=C1 RZPZLFIUFMNCLY-WLHGVMLRSA-N 0.000 claims 6
• METKIMKYRPQLGS-GFCCVEGCSA-N (R)-atenolol Chemical compound CC(C)NC[C@@H](O)COC1=CC=C(CC(N)=O)C=C1 METKIMKYRPQLGS-GFCCVEGCSA-N 0.000 claims 6
• TWBNMYSKRDRHAT-RCWTXCDDSA-N (S)-timolol hemihydrate Chemical compound O.CC(C)(C)NC[C@H](O)COC1=NSN=C1N1CCOCC1.CC(C)(C)NC[C@H](O)COC1=NSN=C1N1CCOCC1 TWBNMYSKRDRHAT-RCWTXCDDSA-N 0.000 claims 6
• FIQOFIRCTOWDOW-BJLQDIEVSA-N 2-[(2S,6R)-6-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]azaniumyl]-5-oxo-2-thiophen-2-yl-1,4-thiazepan-4-yl]acetate Chemical compound C([C@@H](C(=O)OCC)N[C@@H]1C(N(CC(O)=O)C[C@H](SC1)C=1SC=CC=1)=O)CC1=CC=CC=C1 FIQOFIRCTOWDOW-BJLQDIEVSA-N 0.000 claims 6
• NZPSYYOURGWZCM-UHFFFAOYSA-N 2-butyl-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]-1,3-diazaspiro[4.4]non-1-en-4-one;6-chloro-1,1-dioxo-3,4-dihydro-2H-1$l^{6},2,4-benzothiadiazine-7-sulfonamide Chemical compound C1=C(Cl)C(S(=O)(=O)N)=CC2=C1NCNS2(=O)=O.O=C1N(CC=2C=CC(=CC=2)C=2C(=CC=CC=2)C2=NNN=N2)C(CCCC)=NC21CCCC2 NZPSYYOURGWZCM-UHFFFAOYSA-N 0.000 claims 6
• 125000004204 2-methoxyphenyl group Chemical group [H]C1=C([H])C(*)=C(OC([H])([H])[H])C([H])=C1[H] 0.000 claims 6
• KJEBULYHNRNJTE-DHZHZOJOSA-N 3-O-(2-methoxyethyl) 5-O-[(E)-3-phenylprop-2-enyl] 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate Chemical compound COCCOC(=O)C1=C(C)NC(C)=C(C(=O)OC\C=C\C=2C=CC=CC=2)C1C1=CC=CC([N+]([O-])=O)=C1 KJEBULYHNRNJTE-DHZHZOJOSA-N 0.000 claims 6
• JYDQLCKSZZWSEF-UHFFFAOYSA-N 3-benzyl-6-(1,1-difluoroethyl)-1,1-dioxo-3,4-dihydro-2H-1$l^{6},2,4-benzothiadiazine-7-sulfonamide Chemical compound N1S(=O)(=O)C=2C=C(S(N)(=O)=O)C(C(F)(F)C)=CC=2NC1CC1=CC=CC=C1 JYDQLCKSZZWSEF-UHFFFAOYSA-N 0.000 claims 6
• CTPOHARTNNSRSR-APJZLKAGSA-N 4-[(1R,2R,3aS,8bS)-2-hydroxy-1-[(E,3S)-3-hydroxy-4-methyloct-1-en-6-ynyl]-2,3,3a,8b-tetrahydro-1H-cyclopenta[b][1]benzofuran-5-yl]butanoic acid Chemical compound O([C@H]1C[C@@H](O)[C@@H]([C@@H]21)/C=C/[C@@H](O)C(C)CC#CC)C1=C2C=CC=C1CCCC(O)=O CTPOHARTNNSRSR-APJZLKAGSA-N 0.000 claims 6
• LBXHRAWDUMTPSE-AOOOYVTPSA-N 4-chloro-N-[(2S,6R)-2,6-dimethylpiperidin-1-yl]-3-sulfamoylbenzamide Chemical compound C[C@H]1CCC[C@@H](C)N1NC(=O)C1=CC=C(Cl)C(S(N)(=O)=O)=C1 LBXHRAWDUMTPSE-AOOOYVTPSA-N 0.000 claims 6
• 102000034451 ATPases Human genes 0.000 claims 6
• 108091006096 ATPases Proteins 0.000 claims 6
• 229960002122 Acebutolol Drugs 0.000 claims 6
• GOEMGAFJFRBGGG-UHFFFAOYSA-N Acebutolol Chemical compound CCCC(=O)NC1=CC=C(OCC(O)CNC(C)C)C(C(C)=O)=C1 GOEMGAFJFRBGGG-UHFFFAOYSA-N 0.000 claims 6
• PAZJSJFMUHDSTF-UHFFFAOYSA-N Alprenolol Chemical compound CC(C)NCC(O)COC1=CC=CC=C1CC=C PAZJSJFMUHDSTF-UHFFFAOYSA-N 0.000 claims 6
• XSDQTOBWRPYKKA-UHFFFAOYSA-N Amiloride Chemical compound NC(=N)NC(=O)C1=NC(Cl)=C(N)N=C1N XSDQTOBWRPYKKA-UHFFFAOYSA-N 0.000 claims 6
• HTIQEAQVCYTUBX-UHFFFAOYSA-N Amlodipine Chemical compound CCOC(=O)C1=C(COCCN)NC(C)=C(C(=O)OC)C1C1=CC=CC=C1Cl HTIQEAQVCYTUBX-UHFFFAOYSA-N 0.000 claims 6
• 229960002274 Atenolol Drugs 0.000 claims 6
• MOTJMGVDPWRKOC-QPVYNBJUSA-N Atrasentan Chemical compound C1([C@H]2[C@@H]([C@H](CN2CC(=O)N(CCCC)CCCC)C=2C=C3OCOC3=CC=2)C(O)=O)=CC=C(OC)C=C1 MOTJMGVDPWRKOC-QPVYNBJUSA-N 0.000 claims 6
• ZKFQEACEUNWPMT-UHFFFAOYSA-N Azelnidipine Chemical compound CC(C)OC(=O)C1=C(C)NC(N)=C(C(=O)OC2CN(C2)C(C=2C=CC=CC=2)C=2C=CC=CC=2)C1C1=CC=CC([N+]([O-])=O)=C1 ZKFQEACEUNWPMT-UHFFFAOYSA-N 0.000 claims 6
• 229950004646 Azelnidipine Drugs 0.000 claims 6
• NWIUTZDMDHAVTP-UHFFFAOYSA-N Betaxolol Chemical compound C1=CC(OCC(O)CNC(C)C)=CC=C1CCOCC1CC1 NWIUTZDMDHAVTP-UHFFFAOYSA-N 0.000 claims 6
• 229960005400 Bisoprolol Fumarate Drugs 0.000 claims 6
• GJPICJJJRGTNOD-UHFFFAOYSA-N Bosentan Chemical compound COC1=CC=CC=C1OC(C(=NC(=N1)C=2N=CC=CN=2)OCCO)=C1NS(=O)(=O)C1=CC=C(C(C)(C)C)C=C1 GJPICJJJRGTNOD-UHFFFAOYSA-N 0.000 claims 6
• 108010082834 Brain Natriuretic Peptide Proteins 0.000 claims 6
• MAEIEVLCKWDQJH-UHFFFAOYSA-N Bumetanide Chemical compound CCCCNC1=CC(C(O)=O)=CC(S(N)(=O)=O)=C1OC1=CC=CC=C1 MAEIEVLCKWDQJH-UHFFFAOYSA-N 0.000 claims 6
• RHLJLALHBZGAFM-UHFFFAOYSA-N Bunazosinum Chemical compound C1CN(C(=O)CCC)CCCN1C1=NC(N)=C(C=C(OC)C(OC)=C2)C2=N1 RHLJLALHBZGAFM-UHFFFAOYSA-N 0.000 claims 6
• 229940030609 CALCIUM CHANNEL BLOCKERS Drugs 0.000 claims 6
• FAKRSMQSSFJEIM-RQJHMYQMSA-N Captopril Chemical compound SC[C@@H](C)C(=O)N1CCC[C@H]1C(O)=O FAKRSMQSSFJEIM-RQJHMYQMSA-N 0.000 claims 6
• NPAKNKYSJIDKMW-UHFFFAOYSA-N Carvedilol Chemical compound COC1=CC=CC=C1OCCNCC(O)COC1=CC=CC2=NC3=CC=C[CH]C3=C12 NPAKNKYSJIDKMW-UHFFFAOYSA-N 0.000 claims 6
• 229960005025 Cilazapril Drugs 0.000 claims 6
• HHHKFGXWKKUNCY-FHWLQOOXSA-N Cilazapril Chemical compound C([C@@H](C(=O)OCC)N[C@@H]1C(N2[C@@H](CCCN2CCC1)C(O)=O)=O)CC1=CC=CC=C1 HHHKFGXWKKUNCY-FHWLQOOXSA-N 0.000 claims 6
• KPBZROQVTHLCDU-GOSISDBHSA-N Clevidipine Chemical compound CCCC(=O)OCOC(=O)C1=C(C)NC(C)=C(C(=O)OC)[C@H]1C1=CC=CC(Cl)=C1Cl KPBZROQVTHLCDU-GOSISDBHSA-N 0.000 claims 6
• 229960005227 DELAPRIL Drugs 0.000 claims 6
• 229940030606 DIURETICS Drugs 0.000 claims 6
• WOUOLAUOZXOLJQ-MBSDFSHPSA-N Delapril Chemical compound C([C@@H](C(=O)OCC)N[C@@H](C)C(=O)N(CC(O)=O)C1CC2=CC=CC=C2C1)CC1=CC=CC=C1 WOUOLAUOZXOLJQ-MBSDFSHPSA-N 0.000 claims 6
• JZUFKLXOESDKRF-UHFFFAOYSA-N Dichlothiazide Chemical compound C1=C(Cl)C(S(=O)(=O)N)=CC2=C1NCNS2(=O)=O JZUFKLXOESDKRF-UHFFFAOYSA-N 0.000 claims 6
• HSUGRBWQSSZJOP-RTWAWAEBSA-N Diltiazem Chemical compound C1=CC(OC)=CC=C1[C@H]1[C@@H](OC(C)=O)C(=O)N(CCN(C)C)C2=CC=CC=C2S1 HSUGRBWQSSZJOP-RTWAWAEBSA-N 0.000 claims 6
• 102000014469 EC 4.6.1.2 Human genes 0.000 claims 6
• 108010078321 EC 4.6.1.2 Proteins 0.000 claims 6
• 229960000873 Enalapril Drugs 0.000 claims 6
• GBXSMTUPTTWBMN-XIRDDKMYSA-N Enalapril Chemical compound C([C@@H](C(=O)OCC)N[C@@H](C)C(=O)N1[C@@H](CCC1)C(O)=O)CC1=CC=CC=C1 GBXSMTUPTTWBMN-XIRDDKMYSA-N 0.000 claims 6
• 108010061435 Enalapril Proteins 0.000 claims 6
• 108010059378 Endopeptidases Proteins 0.000 claims 6
• 102000005593 Endopeptidases Human genes 0.000 claims 6
• KAQKFAOMNZTLHT-VVUHWYTRSA-N Epoprostenol Chemical compound O1C(=CCCCC(O)=O)C[C@@H]2[C@@H](/C=C/[C@@H](O)CCCCC)[C@H](O)C[C@@H]21 KAQKFAOMNZTLHT-VVUHWYTRSA-N 0.000 claims 6
• ZZUFCTLCJUWOSV-UHFFFAOYSA-N Furosemide Chemical compound C1=C(Cl)C(S(=O)(=O)N)=CC(C(O)=O)=C1NCC1=CC=CO1 ZZUFCTLCJUWOSV-UHFFFAOYSA-N 0.000 claims 6
• 229960003883 Furosemide Drugs 0.000 claims 6
• RPTUSVTUFVMDQK-UHFFFAOYSA-N Hidralazin Chemical compound C1=CC=C2C(NN)=NN=CC2=C1 RPTUSVTUFVMDQK-UHFFFAOYSA-N 0.000 claims 6
• 229960002474 Hydralazine Drugs 0.000 claims 6
• KLZWOWYOHUKJIG-BPUTZDHNSA-N Imidapril Chemical compound C([C@@H](C(=O)OCC)N[C@@H](C)C(=O)N1C(N(C)C[C@H]1C(O)=O)=O)CC1=CC=CC=C1 KLZWOWYOHUKJIG-BPUTZDHNSA-N 0.000 claims 6
• 229960004569 Indapamide Drugs 0.000 claims 6
• NDDAHWYSQHTHNT-UHFFFAOYSA-N Indapamide Chemical compound CC1CC2=CC=CC=C2N1NC(=O)C1=CC=C(Cl)C(S(N)(=O)=O)=C1 NDDAHWYSQHTHNT-UHFFFAOYSA-N 0.000 claims 6
• SGUAFYQXFOLMHL-UHFFFAOYSA-N Labetalol Chemical compound C=1C=C(O)C(C(N)=O)=CC=1C(O)CNC(C)CCC1=CC=CC=C1 SGUAFYQXFOLMHL-UHFFFAOYSA-N 0.000 claims 6
• CEMAWMOMDPGJMB-UHFFFAOYSA-N Laracor Chemical compound CC(C)NCC(O)COC1=CC=CC=C1OCC=C CEMAWMOMDPGJMB-UHFFFAOYSA-N 0.000 claims 6
• 229960004294 Lercanidipine Drugs 0.000 claims 6
• ZDXUKAKRHYTAKV-UHFFFAOYSA-N Lercanidipine Chemical compound COC(=O)C1=C(C)NC(C)=C(C(=O)OC(C)(C)CN(C)CCC(C=2C=CC=CC=2)C=2C=CC=CC=2)C1C1=CC=CC([N+]([O-])=O)=C1 ZDXUKAKRHYTAKV-UHFFFAOYSA-N 0.000 claims 6
• 229960002394 Lisinopril Drugs 0.000 claims 6
• 108010007859 Lisinopril Proteins 0.000 claims 6
• 229960005170 MOEXIPRIL Drugs 0.000 claims 6
• CJCSPKMFHVPWAR-JTQLQIEISA-N Methyldopa Chemical compound OC(=O)[C@](N)(C)CC1=CC=C(O)C(O)=C1 CJCSPKMFHVPWAR-JTQLQIEISA-N 0.000 claims 6
• 229960000615 Methyldopa Drugs 0.000 claims 6
• 229960002237 Metoprolol Drugs 0.000 claims 6
• IUBSYMUCCVWXPE-UHFFFAOYSA-N Metoprolol Chemical compound COCCC1=CC=C(OCC(O)CNC(C)C)C=C1 IUBSYMUCCVWXPE-UHFFFAOYSA-N 0.000 claims 6
• UWWDHYUMIORJTA-HSQYWUDLSA-N Moexipril Chemical compound C([C@@H](C(=O)OCC)N[C@@H](C)C(=O)N1[C@@H](CC2=CC(OC)=C(OC)C=C2C1)C(O)=O)CC1=CC=CC=C1 UWWDHYUMIORJTA-HSQYWUDLSA-N 0.000 claims 6
• QRNMKZJPTYRAIL-UHFFFAOYSA-N N-[2,6-dimethyl-4-[4-[methyl(2-phenylethyl)amino]piperidine-1-carbonyl]phenyl]propanamide;hydrate;hydrochloride Chemical compound O.Cl.C1=C(C)C(NC(=O)CC)=C(C)C=C1C(=O)N1CCC(N(C)CCC=2C=CC=CC=2)CC1 QRNMKZJPTYRAIL-UHFFFAOYSA-N 0.000 claims 6
• KSNUCNRMDYJBKT-UHFFFAOYSA-N N-[3-[4-[4-(2-oxo-3,4-dihydroquinolin-1-yl)piperidine-1-carbonyl]phenoxy]propyl]acetamide Chemical compound C1=CC(OCCCNC(=O)C)=CC=C1C(=O)N1CCC(N2C3=CC=CC=C3CCC2=O)CC1 KSNUCNRMDYJBKT-UHFFFAOYSA-N 0.000 claims 6
• HRRBJVNMSRJFHQ-UHFFFAOYSA-N Naftopidil Chemical compound COC1=CC=CC=C1N1CCN(CC(O)COC=2C3=CC=CC=C3C=CC=2)CC1 HRRBJVNMSRJFHQ-UHFFFAOYSA-N 0.000 claims 6
• 229950005705 Naftopidil Drugs 0.000 claims 6
• 229960001783 Nicardipine Drugs 0.000 claims 6
• ZBBHBTPTTSWHBA-UHFFFAOYSA-N Nicardipine Chemical compound COC(=O)C1=C(C)NC(C)=C(C(=O)OCCN(C)CC=2C=CC=CC=2)C1C1=CC=CC([N+]([O-])=O)=C1 ZBBHBTPTTSWHBA-UHFFFAOYSA-N 0.000 claims 6
• 229960001597 Nifedipine Drugs 0.000 claims 6
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• 125000004658 aryl carbonyl amino group Chemical group 0.000 claims 2
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• YIXSGTRDFWXVGM-UHFFFAOYSA-N azepan-1-yl-[3-bromo-5-(furan-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]methanone Chemical compound N=1N2C(C(F)(F)F)=CC(C=3OC=CC=3)=NC2=C(Br)C=1C(=O)N1CCCCCC1 YIXSGTRDFWXVGM-UHFFFAOYSA-N 0.000 claims 2
• RIYNNDAOGXNYFD-UHFFFAOYSA-N azepan-1-yl-[3-chloro-5-thiophen-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]methanone Chemical compound N=1N2C(C(F)(F)F)=CC(C=3SC=CC=3)=NC2=C(Cl)C=1C(=O)N1CCCCCC1 RIYNNDAOGXNYFD-UHFFFAOYSA-N 0.000 claims 2
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• 125000005026 carboxyaryl group Chemical group 0.000 claims 2
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• 239000003085 diluting agent Substances 0.000 claims 2
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• XWPDRMHCZYSUAO-UHFFFAOYSA-N (3-methylpiperidin-1-yl)-[4-(naphthalen-1-yloxymethyl)phenyl]methanone Chemical compound C1C(C)CCCN1C(=O)C(C=C1)=CC=C1COC1=CC=CC2=CC=CC=C12 XWPDRMHCZYSUAO-UHFFFAOYSA-N 0.000 claims 1
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• FMQBYRINRXIZCS-UHFFFAOYSA-N (4-aminophenyl)-(3,3,5-trimethyl-7-azabicyclo[3.2.1]octan-7-yl)methanone Chemical compound C1C(C)(C)CC(C)(C2)CC1N2C(=O)C1=CC=C(N)C=C1 FMQBYRINRXIZCS-UHFFFAOYSA-N 0.000 claims 1
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• XTBKTQHPFRDAPV-UHFFFAOYSA-N (4-benzylpiperazin-1-yl)-[3-chloro-5-phenyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]methanone Chemical compound N=1N2C(C(F)(F)F)=CC(C=3C=CC=CC=3)=NC2=C(Cl)C=1C(=O)N(CC1)CCN1CC1=CC=CC=C1 XTBKTQHPFRDAPV-UHFFFAOYSA-N 0.000 claims 1
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• UIJMJYUIPKMZQU-UHFFFAOYSA-N (4-benzylpiperazin-1-yl)-[5-(4-methylphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]methanone Chemical compound C1=CC(C)=CC=C1C1=NC2=CC(C(=O)N3CCN(CC=4C=CC=CC=4)CC3)=NN2C(C(F)(F)F)=C1 UIJMJYUIPKMZQU-UHFFFAOYSA-N 0.000 claims 1
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• BMFYTJXTVRXEHG-UHFFFAOYSA-N (4-benzylpiperazin-1-yl)-[5-phenyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-3-yl]methanone Chemical compound C1=NN2C(C(F)(F)F)=CC(C=3C=CC=CC=3)=NC2=C1C(=O)N(CC1)CCN1CC1=CC=CC=C1 BMFYTJXTVRXEHG-UHFFFAOYSA-N 0.000 claims 1
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• QLQZMZMJJLZTDF-UHFFFAOYSA-N (4-benzylpiperidin-1-yl)-(4-methyl-3-nitrophenyl)methanone Chemical compound C1=C([N+]([O-])=O)C(C)=CC=C1C(=O)N1CCC(CC=2C=CC=CC=2)CC1 QLQZMZMJJLZTDF-UHFFFAOYSA-N 0.000 claims 1
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• MUNYRZJABWRQQP-UHFFFAOYSA-N (4-chlorothieno[2,3-b]thiophen-5-yl)-thiomorpholin-4-ylmethanone Chemical compound S1C=2SC=CC=2C(Cl)=C1C(=O)N1CCSCC1 MUNYRZJABWRQQP-UHFFFAOYSA-N 0.000 claims 1
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• XJCXJTTYTZQWJY-UHFFFAOYSA-N (4-ethoxyphenyl)-(4-methylpiperidin-1-yl)methanone Chemical compound C1=CC(OCC)=CC=C1C(=O)N1CCC(C)CC1 XJCXJTTYTZQWJY-UHFFFAOYSA-N 0.000 claims 1
• FPPNHOLKCNLPIC-UHFFFAOYSA-N (4-fluoro-3-morpholin-4-ylsulfonylphenyl)-(3,3,5-trimethyl-7-azabicyclo[3.2.1]octan-7-yl)methanone Chemical compound C1C(C)(C)CC(C)(C2)CC1N2C(=O)C(C=1)=CC=C(F)C=1S(=O)(=O)N1CCOCC1 FPPNHOLKCNLPIC-UHFFFAOYSA-N 0.000 claims 1
• HGOXDUCHIOIWFR-UHFFFAOYSA-N (4-fluorophenyl)-(3-phenylpiperidin-1-yl)methanone Chemical compound C1=CC(F)=CC=C1C(=O)N1CC(C=2C=CC=CC=2)CCC1 HGOXDUCHIOIWFR-UHFFFAOYSA-N 0.000 claims 1
• RJTJHWUTEFLYIT-UHFFFAOYSA-N (4-imidazol-1-ylphenyl)-(3,3,5-trimethyl-7-azabicyclo[3.2.1]octan-7-yl)methanone Chemical compound C1C(C)(C)CC(C)(C2)CC1N2C(=O)C(C=C1)=CC=C1N1C=CN=C1 RJTJHWUTEFLYIT-UHFFFAOYSA-N 0.000 claims 1
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• DQMZVMDRFHMFIT-UHFFFAOYSA-N (4-methylpiperazin-1-yl)-[5-phenyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]methanone Chemical compound C1CN(C)CCN1C(=O)C1=NN2C(C(F)(F)F)=CC(C=3C=CC=CC=3)=NC2=C1 DQMZVMDRFHMFIT-UHFFFAOYSA-N 0.000 claims 1
• FNQBAESOVRNAEY-UHFFFAOYSA-N (4-methylpiperazin-1-yl)-[5-thiophen-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]methanone Chemical compound C1CN(C)CCN1C(=O)C1=NN2C(C(F)(F)F)=CC(C=3SC=CC=3)=NC2=C1 FNQBAESOVRNAEY-UHFFFAOYSA-N 0.000 claims 1
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• AGMHVBMOFHSQOH-UHFFFAOYSA-N (4-methylsulfonylphenyl)-(3,3,5-trimethyl-7-azabicyclo[3.2.1]octan-7-yl)methanone Chemical compound C1C(C)(C)CC(C)(C2)CC1N2C(=O)C1=CC=C(S(C)(=O)=O)C=C1 AGMHVBMOFHSQOH-UHFFFAOYSA-N 0.000 claims 1
• CPLHGZXBIRIPCH-UHFFFAOYSA-N (4-morpholin-4-ylsulfonylphenyl)-(3,3,5-trimethyl-7-azabicyclo[3.2.1]octan-7-yl)methanone Chemical compound C1C(C)(C)CC(C)(C2)CC1N2C(=O)C(C=C1)=CC=C1S(=O)(=O)N1CCOCC1 CPLHGZXBIRIPCH-UHFFFAOYSA-N 0.000 claims 1
• JCIJVASDCBGDOI-UHFFFAOYSA-N (4-nitrophenyl)-(3,3,5-trimethyl-7-azabicyclo[3.2.1]octan-7-yl)methanone Chemical compound C1C(C)(C)CC(C)(C2)CC1N2C(=O)C1=CC=C([N+]([O-])=O)C=C1 JCIJVASDCBGDOI-UHFFFAOYSA-N 0.000 claims 1
• WRDJGRFGSJWADX-UHFFFAOYSA-N (4-phenoxyphenyl)-(3,3,5-trimethyl-7-azabicyclo[3.2.1]octan-7-yl)methanone Chemical compound C1C(C)(C)CC(C)(C2)CC1N2C(=O)C(C=C1)=CC=C1OC1=CC=CC=C1 WRDJGRFGSJWADX-UHFFFAOYSA-N 0.000 claims 1
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• JWMYQXADQAHARQ-UHFFFAOYSA-N (4-phenylpiperazin-1-yl)-pyrazolo[1,5-a]pyrimidin-3-ylmethanone Chemical compound C1=NN2C=CC=NC2=C1C(=O)N(CC1)CCN1C1=CC=CC=C1 JWMYQXADQAHARQ-UHFFFAOYSA-N 0.000 claims 1
• UDJZUOQISGJKEM-UHFFFAOYSA-N (4-pyrazol-1-ylphenyl)-(3,3,5-trimethyl-7-azabicyclo[3.2.1]octan-7-yl)methanone Chemical compound C1C(C)(C)CC(C)(C2)CC1N2C(=O)C(C=C1)=CC=C1N1C=CC=N1 UDJZUOQISGJKEM-UHFFFAOYSA-N 0.000 claims 1
• NEQPSQNLANNXIT-UHFFFAOYSA-N (4-pyrrol-1-ylphenyl)-(3,3,5-trimethyl-7-azabicyclo[3.2.1]octan-7-yl)methanone Chemical compound C1C(C)(C)CC(C)(C2)CC1N2C(=O)C(C=C1)=CC=C1N1C=CC=C1 NEQPSQNLANNXIT-UHFFFAOYSA-N 0.000 claims 1
• MCAFPYGLGZLOSR-UHFFFAOYSA-N (4-tert-butylcyclohexyl) 4-oxo-4-piperidin-1-ylbutanoate Chemical compound C1CC(C(C)(C)C)CCC1OC(=O)CCC(=O)N1CCCCC1 MCAFPYGLGZLOSR-UHFFFAOYSA-N 0.000 claims 1
• AKKAEPNNCZKJEW-UHFFFAOYSA-N (4-tert-butylphenyl)-(3,4-dihydro-1H-isoquinolin-2-yl)methanone Chemical compound C1=CC(C(C)(C)C)=CC=C1C(=O)N1CC2=CC=CC=C2CC1 AKKAEPNNCZKJEW-UHFFFAOYSA-N 0.000 claims 1
• RIOYYMWXYHNMFV-UHFFFAOYSA-N (4-tert-butylphenyl)-(3,5-dimethylpiperidin-1-yl)methanone Chemical compound C1C(C)CC(C)CN1C(=O)C1=CC=C(C(C)(C)C)C=C1 RIOYYMWXYHNMFV-UHFFFAOYSA-N 0.000 claims 1
• SWHJJCBDEZPXDK-UHFFFAOYSA-N (4-tert-butylpiperidin-1-yl)-(1H-indol-5-yl)methanone Chemical compound C1CC(C(C)(C)C)CCN1C(=O)C1=CC=C(NC=C2)C2=C1 SWHJJCBDEZPXDK-UHFFFAOYSA-N 0.000 claims 1
• UVPFTRNYXLMKBI-UHFFFAOYSA-N (4-tert-butylpiperidin-1-yl)-phenylmethanone Chemical compound C1CC(C(C)(C)C)CCN1C(=O)C1=CC=CC=C1 UVPFTRNYXLMKBI-UHFFFAOYSA-N 0.000 claims 1
• JDSAXUNMKVGZFP-UHFFFAOYSA-N (5,7-dimethylpyrazolo[1,5-a]pyrimidin-3-yl)-[4-(4-methoxyphenyl)piperazin-1-yl]methanone Chemical compound C1=CC(OC)=CC=C1N1CCN(C(=O)C2=C3N=C(C)C=C(C)N3N=C2)CC1 JDSAXUNMKVGZFP-UHFFFAOYSA-N 0.000 claims 1
• IIGSWXMILZRIAD-UHFFFAOYSA-N (5,7-dimethylpyrazolo[1,5-a]pyrimidin-3-yl)-piperidin-1-ylmethanone Chemical compound C=12N=C(C)C=C(C)N2N=CC=1C(=O)N1CCCCC1 IIGSWXMILZRIAD-UHFFFAOYSA-N 0.000 claims 1
• SSFOKALIBRZBAB-UHFFFAOYSA-N (5,7-diphenylpyrazolo[1,5-a]pyrimidin-2-yl)-(4-methylpiperazin-1-yl)methanone Chemical compound C1CN(C)CCN1C(=O)C1=NN2C(C=3C=CC=CC=3)=CC(C=3C=CC=CC=3)=NC2=C1 SSFOKALIBRZBAB-UHFFFAOYSA-N 0.000 claims 1
• KYRBNQQPHRGLIA-UHFFFAOYSA-N (5,7-diphenylpyrazolo[1,5-a]pyrimidin-2-yl)-(4-phenylpiperazin-1-yl)methanone Chemical compound C1=C2N=C(C=3C=CC=CC=3)C=C(C=3C=CC=CC=3)N2N=C1C(=O)N(CC1)CCN1C1=CC=CC=C1 KYRBNQQPHRGLIA-UHFFFAOYSA-N 0.000 claims 1
• AISGVQRKOVTTFF-UHFFFAOYSA-N (5,7-diphenylpyrazolo[1,5-a]pyrimidin-2-yl)-pyrrolidin-1-ylmethanone Chemical compound C1=C2N=C(C=3C=CC=CC=3)C=C(C=3C=CC=CC=3)N2N=C1C(=O)N1CCCC1 AISGVQRKOVTTFF-UHFFFAOYSA-N 0.000 claims 1
• RZNRAZVOGLCVQE-UHFFFAOYSA-N (5,7-diphenylpyrazolo[1,5-a]pyrimidin-3-yl)-(4-methylpiperazin-1-yl)methanone Chemical compound C1CN(C)CCN1C(=O)C1=C2N=C(C=3C=CC=CC=3)C=C(C=3C=CC=CC=3)N2N=C1 RZNRAZVOGLCVQE-UHFFFAOYSA-N 0.000 claims 1
• QNEWOOLTUCRPRE-UHFFFAOYSA-N (5-benzyl-2,5-diazabicyclo[2.2.1]heptan-2-yl)-(1H-indol-5-yl)methanone Chemical compound C=1C=C2NC=CC2=CC=1C(=O)N1CC2CC1CN2CC1=CC=CC=C1 QNEWOOLTUCRPRE-UHFFFAOYSA-N 0.000 claims 1
• ZVUBXZNFCSHIHY-UHFFFAOYSA-N (5-chloro-1H-indol-3-yl)-(3,3,5-trimethyl-7-azabicyclo[3.2.1]octan-7-yl)methanone Chemical compound C1=C(Cl)C=C2C(C(=O)N3C4CC(CC(C)(C)C4)(C3)C)=CNC2=C1 ZVUBXZNFCSHIHY-UHFFFAOYSA-N 0.000 claims 1
• KAPCFYNJZGEHHE-UHFFFAOYSA-N (5-methoxy-1H-indol-3-yl)-(3,3,5-trimethyl-7-azabicyclo[3.2.1]octan-7-yl)methanone Chemical compound C1C(CC(C)(C)C2)(C)CC2N1C(=O)C1=CNC2=CC=C(OC)C=C21 KAPCFYNJZGEHHE-UHFFFAOYSA-N 0.000 claims 1
• MIVULGWLDDPYFH-UHFFFAOYSA-N (5-methyl-7-phenylpyrazolo[1,5-a]pyrimidin-3-yl)-(3,3,5-trimethyl-7-azabicyclo[3.2.1]octan-7-yl)methanone Chemical compound N12N=CC(C(=O)N3C4CC(CC(C)(C)C4)(C)C3)=C2N=C(C)C=C1C1=CC=CC=C1 MIVULGWLDDPYFH-UHFFFAOYSA-N 0.000 claims 1
• XKXHHPFVZIJSMO-UHFFFAOYSA-N (5-phenylmethoxy-1H-indol-3-yl)-(3,3,5-trimethyl-7-azabicyclo[3.2.1]octan-7-yl)methanone Chemical compound C1C(C)(C)CC(C)(C2)CC1N2C(=O)C(C1=C2)=CNC1=CC=C2OCC1=CC=CC=C1 XKXHHPFVZIJSMO-UHFFFAOYSA-N 0.000 claims 1
• FXHGZHRIDSZIBA-UHFFFAOYSA-N (6-bromo-3-chloropyrazolo[1,5-a]pyrimidin-2-yl)-morpholin-4-ylmethanone Chemical compound N=1N2C=C(Br)C=NC2=C(Cl)C=1C(=O)N1CCOCC1 FXHGZHRIDSZIBA-UHFFFAOYSA-N 0.000 claims 1
• PZYUJIUSALQNPF-UHFFFAOYSA-N (6-bromopyrazolo[1,5-a]pyrimidin-2-yl)-morpholin-4-ylmethanone Chemical compound N=1N2C=C(Br)C=NC2=CC=1C(=O)N1CCOCC1 PZYUJIUSALQNPF-UHFFFAOYSA-N 0.000 claims 1
• UCFRNGOVUCOFOV-UHFFFAOYSA-N (6-bromopyrazolo[1,5-a]pyrimidin-2-yl)-piperidin-1-ylmethanone Chemical compound N=1N2C=C(Br)C=NC2=CC=1C(=O)N1CCCCC1 UCFRNGOVUCOFOV-UHFFFAOYSA-N 0.000 claims 1
• SKBKNXKJJFNDEY-UHFFFAOYSA-N (6-fluoro-1H-indol-3-yl)-(3,3,5-trimethyl-7-azabicyclo[3.2.1]octan-7-yl)methanone Chemical compound FC1=CC=C2C(C(=O)N3C4CC(CC(C)(C)C4)(C3)C)=CNC2=C1 SKBKNXKJJFNDEY-UHFFFAOYSA-N 0.000 claims 1
• XTESOSQZUQYBLP-UHFFFAOYSA-N (6-fluoro-2-methyl-3,4-dihydro-2H-quinolin-1-yl)-(2-fluorophenyl)methanone Chemical compound CC1CCC2=CC(F)=CC=C2N1C(=O)C1=CC=CC=C1F XTESOSQZUQYBLP-UHFFFAOYSA-N 0.000 claims 1
• LQPZEMSOVCESFL-UHFFFAOYSA-N (6-fluoro-2-methyl-3,4-dihydro-2H-quinolin-1-yl)-(3,4,5-trimethoxyphenyl)methanone Chemical compound COC1=C(OC)C(OC)=CC(C(=O)N2C3=CC=C(F)C=C3CCC2C)=C1 LQPZEMSOVCESFL-UHFFFAOYSA-N 0.000 claims 1
• KDMOVEXDMQZEPS-UHFFFAOYSA-N (6-fluoro-2-methyl-3,4-dihydro-2H-quinolin-1-yl)-[3-(trifluoromethyl)phenyl]methanone Chemical compound CC1CCC2=CC(F)=CC=C2N1C(=O)C1=CC=CC(C(F)(F)F)=C1 KDMOVEXDMQZEPS-UHFFFAOYSA-N 0.000 claims 1
• ZBCLYMFHPMQQSS-UHFFFAOYSA-N (6-fluoro-2-methyl-3,4-dihydro-2H-quinolin-1-yl)-phenylmethanone Chemical compound CC1CCC2=CC(F)=CC=C2N1C(=O)C1=CC=CC=C1 ZBCLYMFHPMQQSS-UHFFFAOYSA-N 0.000 claims 1
• OWOBXOSMLOWFEN-UHFFFAOYSA-N (6-methoxy-1H-indol-3-yl)-(3,3,5-trimethyl-7-azabicyclo[3.2.1]octan-7-yl)methanone Chemical compound C1C(CC(C)(C)C2)(C)CC2N1C(=O)C1=CNC2=CC(OC)=CC=C21 OWOBXOSMLOWFEN-UHFFFAOYSA-N 0.000 claims 1
• FGVHXWMGZMGETK-UHFFFAOYSA-N (6-methyl-1H-indol-3-yl)-(3,3,5-trimethyl-7-azabicyclo[3.2.1]octan-7-yl)methanone Chemical compound C1C(CC(C)(C)C2)(C)CC2N1C(=O)C1=CNC2=CC(C)=CC=C21 FGVHXWMGZMGETK-UHFFFAOYSA-N 0.000 claims 1
• MUDWIJMMYALAGU-UHFFFAOYSA-N (6-nitro-1H-indol-3-yl)-(3,3,5-trimethyl-7-azabicyclo[3.2.1]octan-7-yl)methanone Chemical compound [O-][N+](=O)C1=CC=C2C(C(=O)N3C4CC(CC(C)(C)C4)(C3)C)=CNC2=C1 MUDWIJMMYALAGU-UHFFFAOYSA-N 0.000 claims 1
• SRLQPYSHHSLQKQ-UHFFFAOYSA-N (6-pyrazol-1-ylpyridin-3-yl)-(3,3,5-trimethyl-7-azabicyclo[3.2.1]octan-7-yl)methanone Chemical compound C1C(C)(C)CC(C)(C2)CC1N2C(=O)C(C=N1)=CC=C1N1C=CC=N1 SRLQPYSHHSLQKQ-UHFFFAOYSA-N 0.000 claims 1
• KZDCJZBODQFPAX-SDNWHVSQSA-N (6E)-6-[5-(2-oxo-2-piperidin-1-ylethyl)sulfanyl-3H-1,3,4-oxadiazol-2-ylidene]cyclohexa-2,4-dien-1-one Chemical compound C1CCCCN1C(=O)CSC(O1)=NN\C1=C1\C=CC=CC1=O KZDCJZBODQFPAX-SDNWHVSQSA-N 0.000 claims 1
• HVMDTGSDSRRYTQ-UHFFFAOYSA-N (7-hydroxy-3,4,4a,5,6,7,8,8a-octahydro-2H-quinolin-1-yl)-phenylmethanone Chemical compound C12CC(O)CCC2CCCN1C(=O)C1=CC=CC=C1 HVMDTGSDSRRYTQ-UHFFFAOYSA-N 0.000 claims 1
• ZJZMGANTZSBHJZ-UHFFFAOYSA-N (7-methyl-5-phenylpyrazolo[1,5-a]pyrimidin-2-yl)-(4-methylpiperidin-1-yl)methanone Chemical compound C1CC(C)CCN1C(=O)C1=NN2C(C)=CC(C=3C=CC=CC=3)=NC2=C1 ZJZMGANTZSBHJZ-UHFFFAOYSA-N 0.000 claims 1
• OBAHMYACYJAVMR-UHFFFAOYSA-N (7-methyl-5-phenylpyrazolo[1,5-a]pyrimidin-2-yl)-morpholin-4-ylmethanone Chemical compound N=1N2C(C)=CC(C=3C=CC=CC=3)=NC2=CC=1C(=O)N1CCOCC1 OBAHMYACYJAVMR-UHFFFAOYSA-N 0.000 claims 1
• GYRDOUDWHIINOV-UHFFFAOYSA-N (7-methyl-5-phenylpyrazolo[1,5-a]pyrimidin-2-yl)-piperidin-1-ylmethanone Chemical compound N=1N2C(C)=CC(C=3C=CC=CC=3)=NC2=CC=1C(=O)N1CCCCC1 GYRDOUDWHIINOV-UHFFFAOYSA-N 0.000 claims 1
• HBPPEAAQEOKRFE-UHFFFAOYSA-N (7-methyl-5-phenylpyrazolo[1,5-a]pyrimidin-2-yl)-pyrrolidin-1-ylmethanone Chemical compound N=1N2C(C)=CC(C=3C=CC=CC=3)=NC2=CC=1C(=O)N1CCCC1 HBPPEAAQEOKRFE-UHFFFAOYSA-N 0.000 claims 1
• LBVCKSDEHLTWSN-UHFFFAOYSA-N (7-nitro-1H-indol-3-yl)-(3,3,5-trimethyl-7-azabicyclo[3.2.1]octan-7-yl)methanone Chemical compound C1=CC=C2C(C(=O)N3C4CC(CC(C)(C)C4)(C3)C)=CNC2=C1[N+]([O-])=O LBVCKSDEHLTWSN-UHFFFAOYSA-N 0.000 claims 1
• NMKPJBQCDRCXCE-FMIVXFBMSA-N (E)-1-(3,4-dihydro-2H-quinolin-1-yl)-3-(4-fluorophenyl)prop-2-en-1-one Chemical compound C1=CC(F)=CC=C1\C=C\C(=O)N1C2=CC=CC=C2CCC1 NMKPJBQCDRCXCE-FMIVXFBMSA-N 0.000 claims 1
• OOMKTYGUCMJELR-UHFFFAOYSA-N 1,2,3,4,4a,5,6,7,8,8a-decahydronaphthalen-1-yl-(4-methylpiperazin-1-yl)methanone Chemical compound C1CN(C)CCN1C(=O)C1C2CCCCC2CCC1 OOMKTYGUCMJELR-UHFFFAOYSA-N 0.000 claims 1
• DWLZWPXFRMKZOE-UHFFFAOYSA-N 1,3-benzodioxol-5-yl(3,4-dihydro-2H-quinolin-1-yl)methanone Chemical compound C1=C2OCOC2=CC(C(N2C3=CC=CC=C3CCC2)=O)=C1 DWLZWPXFRMKZOE-UHFFFAOYSA-N 0.000 claims 1
• NGALFKPFMUEMSJ-UHFFFAOYSA-N 1,3-benzodioxol-5-yl-(4-benzylpiperidin-1-yl)methanone Chemical compound C=1C=C2OCOC2=CC=1C(=O)N(CC1)CCC1CC1=CC=CC=C1 NGALFKPFMUEMSJ-UHFFFAOYSA-N 0.000 claims 1
• WNXJIVFYUVYPPR-UHFFFAOYSA-N 1,3-dioxolane Chemical compound C1COCO1 WNXJIVFYUVYPPR-UHFFFAOYSA-N 0.000 claims 1
• HLFAONVRFNKIRI-UHFFFAOYSA-N 1-(1,3-benzothiazol-2-yl)-2-[(4-ethyl-5-phenyl-1,2,4-triazol-3-yl)sulfanyl]ethanone Chemical compound CCN1C(SCC(=O)C=2SC3=CC=CC=C3N=2)=NN=C1C1=CC=CC=C1 HLFAONVRFNKIRI-UHFFFAOYSA-N 0.000 claims 1
• QVYNJEKIYOVTPN-UHFFFAOYSA-N 1-(1-adamantyl)-2-(benzylamino)ethanone Chemical compound C1C(C2)CC(C3)CC2CC13C(=O)CNCC1=CC=CC=C1 QVYNJEKIYOVTPN-UHFFFAOYSA-N 0.000 claims 1
• GLJRNCZYMLAOAN-UHFFFAOYSA-N 1-(1-adamantyl)-2-(benzylamino)propan-1-one Chemical compound C1C(C2)CC(C3)CC2CC13C(=O)C(C)NCC1=CC=CC=C1 GLJRNCZYMLAOAN-UHFFFAOYSA-N 0.000 claims 1
• HRTGQJLFHQTMHT-UHFFFAOYSA-N 1-(1-adamantyl)-2-[(4-methyl-1,2,4-triazol-3-yl)sulfanyl]ethanone Chemical compound CN1C=NN=C1SCC(=O)C1(C2)CC(C3)CC2CC3C1 HRTGQJLFHQTMHT-UHFFFAOYSA-N 0.000 claims 1
• ZJDFMILECULDIT-UHFFFAOYSA-N 1-(1-adamantyl)-2-[4-(4-nitrophenyl)piperazin-1-yl]ethanone Chemical compound C1=CC([N+](=O)[O-])=CC=C1N1CCN(CC(=O)C23CC4CC(CC(C4)C2)C3)CC1 ZJDFMILECULDIT-UHFFFAOYSA-N 0.000 claims 1
• QOSICGDZMREYHU-UHFFFAOYSA-N 1-(1-adamantyl)-2-morpholin-4-ylethanone Chemical compound C1C(C2)CC(C3)CC2CC13C(=O)CN1CCOCC1 QOSICGDZMREYHU-UHFFFAOYSA-N 0.000 claims 1
• UEFNQWNUXWBVSN-UHFFFAOYSA-N 1-(1-adamantyl)-2-morpholin-4-ylpropan-1-one Chemical compound C1C(C2)CC(C3)CC2CC13C(=O)C(C)N1CCOCC1 UEFNQWNUXWBVSN-UHFFFAOYSA-N 0.000 claims 1
• XXJASKNHKIDKTP-UHFFFAOYSA-N 1-(1-adamantyl)-4-bromo-N,N-diethylpyrazole-3-carboxamide Chemical compound C1=C(Br)C(C(=O)N(CC)CC)=NN1C1(C2)CC(C3)CC2CC3C1 XXJASKNHKIDKTP-UHFFFAOYSA-N 0.000 claims 1
• DNEGOUQSPGEVCS-UHFFFAOYSA-N 1-(1H-indole-5-carbonyl)-4-phenylpiperidine-4-carbonitrile Chemical compound C=1C=C2NC=CC2=CC=1C(=O)N(CC1)CCC1(C#N)C1=CC=CC=C1 DNEGOUQSPGEVCS-UHFFFAOYSA-N 0.000 claims 1
• HNQAMJPNGVKODD-UHFFFAOYSA-N 1-(2,3-dihydroindol-1-yl)-2-(4-methylphenyl)sulfanylethanone Chemical compound C1=CC(C)=CC=C1SCC(=O)N1C2=CC=CC=C2CC1 HNQAMJPNGVKODD-UHFFFAOYSA-N 0.000 claims 1
• RODREYUVBDOVGG-UHFFFAOYSA-N 1-(2,6-dimethylmorpholin-4-yl)-3,3-diphenylpropan-1-one Chemical compound C1C(C)OC(C)CN1C(=O)CC(C=1C=CC=CC=1)C1=CC=CC=C1 RODREYUVBDOVGG-UHFFFAOYSA-N 0.000 claims 1
• LFQXSKLNWOVHAF-UHFFFAOYSA-N 1-(3,4-dihydro-1H-isoquinolin-2-yl)-2-(2-methoxyphenyl)ethanone Chemical compound COC1=CC=CC=C1CC(=O)N1CC2=CC=CC=C2CC1 LFQXSKLNWOVHAF-UHFFFAOYSA-N 0.000 claims 1
• GLMROUFOILIMJW-UHFFFAOYSA-N 1-(3,4-dihydro-2H-quinolin-1-yl)-2-(1-naphthalen-1-yltetrazol-5-yl)sulfanylethanone Chemical compound C1CCC2=CC=CC=C2N1C(=O)CSC1=NN=NN1C1=CC=CC2=CC=CC=C12 GLMROUFOILIMJW-UHFFFAOYSA-N 0.000 claims 1
• CJVWJHDVLKCEQQ-UHFFFAOYSA-N 1-(3,4-dihydro-2H-quinolin-1-yl)-2-(2-methylphenoxy)ethanone Chemical compound CC1=CC=CC=C1OCC(=O)N1C2=CC=CC=C2CCC1 CJVWJHDVLKCEQQ-UHFFFAOYSA-N 0.000 claims 1
• AHXYHSZRKIFPJS-UHFFFAOYSA-N 1-(3,4-dihydro-2H-quinolin-1-yl)-2-[(4-ethyl-5-phenyl-1,2,4-triazol-3-yl)sulfanyl]ethanone Chemical compound CCN1C(SCC(=O)N2C3=CC=CC=C3CCC2)=NN=C1C1=CC=CC=C1 AHXYHSZRKIFPJS-UHFFFAOYSA-N 0.000 claims 1
• JIBVZRQIEXMYLF-UHFFFAOYSA-N 1-(3,4-dihydro-2H-quinolin-1-yl)-2-[[4-(2-phenylethyl)-5-pyridin-4-yl-1,2,4-triazol-3-yl]sulfanyl]ethanone Chemical compound C1CCC2=CC=CC=C2N1C(=O)CSC(N1CCC=2C=CC=CC=2)=NN=C1C1=CC=NC=C1 JIBVZRQIEXMYLF-UHFFFAOYSA-N 0.000 claims 1
• OCPQRJZNIIWJJG-UHFFFAOYSA-N 1-(3,4-dihydro-2H-quinolin-1-yl)-2-[[4-ethyl-5-[(4-fluoroanilino)methyl]-1,2,4-triazol-3-yl]sulfanyl]ethanone Chemical compound N=1N=C(SCC(=O)N2C3=CC=CC=C3CCC2)N(CC)C=1CNC1=CC=C(F)C=C1 OCPQRJZNIIWJJG-UHFFFAOYSA-N 0.000 claims 1
• WKFABOAGIPBQAF-UHFFFAOYSA-N 1-(3,4-dihydro-2H-quinolin-1-yl)-2-[[5-[(2,4-dimethylanilino)methyl]-4-ethyl-1,2,4-triazol-3-yl]sulfanyl]ethanone Chemical compound N=1N=C(SCC(=O)N2C3=CC=CC=C3CCC2)N(CC)C=1CNC1=CC=C(C)C=C1C WKFABOAGIPBQAF-UHFFFAOYSA-N 0.000 claims 1
• OOEQWCOFVOVUKD-UHFFFAOYSA-N 1-(3-azabicyclo[3.2.2]nonan-3-yl)-2-(1-methylindol-3-yl)ethanone Chemical compound C1CC(C2)CCC1CN2C(=O)CC1=CN(C)C2=CC=CC=C21 OOEQWCOFVOVUKD-UHFFFAOYSA-N 0.000 claims 1
• QFYYSPRBUSHJER-UHFFFAOYSA-N 1-(3-azabicyclo[3.2.2]nonan-3-yl)-2-(1H-indol-3-yl)ethanone Chemical compound C1CC(C2)CCC1CN2C(=O)CC1=CNC2=CC=CC=C12 QFYYSPRBUSHJER-UHFFFAOYSA-N 0.000 claims 1
• WLOBCFIHIQQBKX-UHFFFAOYSA-N 1-(4-aminophenyl)-N-cyclohexyl-N,5-dimethylpyrazole-4-carboxamide Chemical compound C1=NN(C=2C=CC(N)=CC=2)C(C)=C1C(=O)N(C)C1CCCCC1 WLOBCFIHIQQBKX-UHFFFAOYSA-N 0.000 claims 1
• JFUMQHLNKIOHTC-UHFFFAOYSA-N 1-(4-benzylpiperazin-1-yl)-2-[2-(4-chlorophenyl)-2-adamantyl]ethanone Chemical compound C1=CC(Cl)=CC=C1C1(CC(=O)N2CCN(CC=3C=CC=CC=3)CC2)C(C2)CC3CC2CC1C3 JFUMQHLNKIOHTC-UHFFFAOYSA-N 0.000 claims 1
• KKWSMSBRJWEUDS-UHFFFAOYSA-N 1-(4-benzylpiperidin-1-yl)-2-benzylsulfanylethanone Chemical compound C1CC(CC=2C=CC=CC=2)CCN1C(=O)CSCC1=CC=CC=C1 KKWSMSBRJWEUDS-UHFFFAOYSA-N 0.000 claims 1
• RNJWUQAUYSZDEG-UHFFFAOYSA-N 1-(4-bromophenyl)-2-[[4-(furan-2-ylmethyl)-5-pyridin-4-yl-1,2,4-triazol-3-yl]sulfanyl]ethanone Chemical compound C1=CC(Br)=CC=C1C(=O)CSC(N1CC=2OC=CC=2)=NN=C1C1=CC=NC=C1 RNJWUQAUYSZDEG-UHFFFAOYSA-N 0.000 claims 1
• LABLZKSZGSYJKL-UHFFFAOYSA-N 1-(4-bromophenyl)-2-[[5-(furan-2-yl)-4-methyl-1,2,4-triazol-3-yl]sulfanyl]ethanone Chemical compound N=1N=C(C=2OC=CC=2)N(C)C=1SCC(=O)C1=CC=C(Br)C=C1 LABLZKSZGSYJKL-UHFFFAOYSA-N 0.000 claims 1
• CAGPERBEPLUXOK-UHFFFAOYSA-N 1-(4-chlorobenzoyl)-2,3-dihydrobenzo[g]quinolin-4-one Chemical compound C1=CC(Cl)=CC=C1C(=O)N1C2=CC3=CC=CC=C3C=C2C(=O)CC1 CAGPERBEPLUXOK-UHFFFAOYSA-N 0.000 claims 1
• ZUPUABHOCRSLRE-UHFFFAOYSA-N 1-(4-chlorophenyl)-2-[[4-methyl-5-(4-methylphenyl)-1,2,4-triazol-3-yl]sulfanyl]ethanone Chemical compound C1=CC(C)=CC=C1C(N1C)=NN=C1SCC(=O)C1=CC=C(Cl)C=C1 ZUPUABHOCRSLRE-UHFFFAOYSA-N 0.000 claims 1
• ROIJMAYXBGSVHD-UHFFFAOYSA-N 1-(4-chlorophenyl)-2-[[4-methyl-5-[4-(trifluoromethyl)pyridin-3-yl]-1,2,4-triazol-3-yl]sulfanyl]ethanone Chemical compound N=1N=C(C=2C(=CC=NC=2)C(F)(F)F)N(C)C=1SCC(=O)C1=CC=C(Cl)C=C1 ROIJMAYXBGSVHD-UHFFFAOYSA-N 0.000 claims 1
• SNVPQIRFGLLEPM-UHFFFAOYSA-N 1-(4-chlorophenyl)-N-cyclohexyl-N,5-dimethylpyrazole-4-carboxamide Chemical compound C1=NN(C=2C=CC(Cl)=CC=2)C(C)=C1C(=O)N(C)C1CCCCC1 SNVPQIRFGLLEPM-UHFFFAOYSA-N 0.000 claims 1
• TXOIGTCLNINOIR-UHFFFAOYSA-N 1-(4-chlorophenyl)-N-cyclohexyl-N-methyl-5-(trifluoromethyl)pyrazole-4-carboxamide Chemical compound C1=NN(C=2C=CC(Cl)=CC=2)C(C(F)(F)F)=C1C(=O)N(C)C1CCCCC1 TXOIGTCLNINOIR-UHFFFAOYSA-N 0.000 claims 1
• VQDYEQMWMKSMOT-UHFFFAOYSA-N 1-(4-chlorophenyl)-N-cyclohexyl-N-methyl-5-propylpyrazole-4-carboxamide Chemical compound CCCC1=C(C(=O)N(C)C2CCCCC2)C=NN1C1=CC=C(Cl)C=C1 VQDYEQMWMKSMOT-UHFFFAOYSA-N 0.000 claims 1
• JCTGUFVPNTUQRA-UHFFFAOYSA-N 1-(4-ethylbenzoyl)-6-methoxy-2-methyl-2,3-dihydroquinolin-4-one Chemical compound C1=CC(CC)=CC=C1C(=O)N1C2=CC=C(OC)C=C2C(=O)CC1C JCTGUFVPNTUQRA-UHFFFAOYSA-N 0.000 claims 1
• ARSGBHLXHQNDKF-UHFFFAOYSA-N 1-(4-fluorophenyl)-2-[(4-methyl-5-phenyl-1,2,4-triazol-3-yl)sulfanyl]ethanone Chemical compound N=1N=C(C=2C=CC=CC=2)N(C)C=1SCC(=O)C1=CC=C(F)C=C1 ARSGBHLXHQNDKF-UHFFFAOYSA-N 0.000 claims 1
• FITANMHEOCKQFD-UHFFFAOYSA-N 1-(4-fluorophenyl)-4-[(4-methyl-5-phenyl-1,2,4-triazol-3-yl)sulfanyl]butan-1-one;2-[(4-methyl-5-phenyl-1,2,4-triazol-3-yl)sulfanyl]-1-(5,6,7,8-tetrahydronaphthalen-2-yl)ethanone Chemical compound N=1N=C(C=2C=CC=CC=2)N(C)C=1SCCCC(=O)C1=CC=C(F)C=C1.CN1C(SCC(=O)C=2C=C3CCCCC3=CC=2)=NN=C1C1=CC=CC=C1 FITANMHEOCKQFD-UHFFFAOYSA-N 0.000 claims 1
• JGMZKVWWDYIGBR-UHFFFAOYSA-N 1-(4-methoxyphenyl)-2-[[4-(2-phenylethyl)-5-pyridin-4-yl-1,2,4-triazol-3-yl]sulfanyl]ethanone Chemical compound C1=CC(OC)=CC=C1C(=O)CSC(N1CCC=2C=CC=CC=2)=NN=C1C1=CC=NC=C1 JGMZKVWWDYIGBR-UHFFFAOYSA-N 0.000 claims 1
• LWBSCBZYYQRHKA-UHFFFAOYSA-N 1-(4-methoxyphenyl)-2-[[4-methyl-5-(2-methylphenyl)-1,2,4-triazol-3-yl]sulfanyl]ethanone Chemical compound C1=CC(OC)=CC=C1C(=O)CSC(N1C)=NN=C1C1=CC=CC=C1C LWBSCBZYYQRHKA-UHFFFAOYSA-N 0.000 claims 1
• XXMKZAKAWTXDHT-UHFFFAOYSA-N 1-(4-methoxyphenyl)-2-[[4-methyl-5-(4-nitrophenyl)-1,2,4-triazol-3-yl]sulfanyl]ethanone Chemical compound C1=CC(OC)=CC=C1C(=O)CSC(N1C)=NN=C1C1=CC=C([N+]([O-])=O)C=C1 XXMKZAKAWTXDHT-UHFFFAOYSA-N 0.000 claims 1
• NMKQVFRVDXXVSD-UHFFFAOYSA-N 1-(4-methoxyphenyl)-2-[[5-phenyl-4-(2-phenylethyl)-1,2,4-triazol-3-yl]sulfanyl]ethanone Chemical compound C1=CC(OC)=CC=C1C(=O)CSC(N1CCC=2C=CC=CC=2)=NN=C1C1=CC=CC=C1 NMKQVFRVDXXVSD-UHFFFAOYSA-N 0.000 claims 1
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• ZKRNMJOSVPSYAG-UHFFFAOYSA-N 1-adamantyl-(4-phenylpiperidin-1-yl)methanone Chemical compound C1C(C2)CC(C3)CC2CC13C(=O)N(CC1)CCC1C1=CC=CC=C1 ZKRNMJOSVPSYAG-UHFFFAOYSA-N 0.000 claims 1
• VKHJBJDJMJNHDQ-UHFFFAOYSA-N 1-adamantyl-[4-(1H-benzimidazol-2-ylsulfanyl)piperidin-1-yl]methanone Chemical compound C1C(C2)CC(C3)CC2CC13C(=O)N1CCC(SC=2NC3=CC=CC=C3N=2)CC1 VKHJBJDJMJNHDQ-UHFFFAOYSA-N 0.000 claims 1
• KSRHDINKWJNBBG-UHFFFAOYSA-N 1-adamantyl-[4-(2-methoxyphenyl)piperazin-1-yl]methanone Chemical compound COC1=CC=CC=C1N1CCN(C(=O)C23CC4CC(CC(C4)C2)C3)CC1 KSRHDINKWJNBBG-UHFFFAOYSA-N 0.000 claims 1
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• WTALDMNFCQBHCT-UHFFFAOYSA-N 1-morpholin-4-yl-2-[3-(4-nitrophenyl)-1-adamantyl]ethanone Chemical compound C1=CC([N+](=O)[O-])=CC=C1C1(C2)CC(CC(=O)N3CCOCC3)(C3)CC2CC3C1 WTALDMNFCQBHCT-UHFFFAOYSA-N 0.000 claims 1
• ZEFYGKFMGWFRFW-UHFFFAOYSA-N 1-octanoyl-4-phenylpiperidine-4-carbonitrile Chemical compound C1CN(C(=O)CCCCCCC)CCC1(C#N)C1=CC=CC=C1 ZEFYGKFMGWFRFW-UHFFFAOYSA-N 0.000 claims 1
• MDCYTDPPZISTPR-UHFFFAOYSA-N 1-phenyl-2-[[4-(2-phenylethyl)-5-pyridin-3-yl-1,2,4-triazol-3-yl]sulfanyl]ethanone Chemical compound C=1C=CC=CC=1C(=O)CSC(N1CCC=2C=CC=CC=2)=NN=C1C1=CC=CN=C1 MDCYTDPPZISTPR-UHFFFAOYSA-N 0.000 claims 1
• XNVSRSJSSNLZHI-UHFFFAOYSA-N 1-phenyl-2-[[4-(2-phenylethyl)-5-pyridin-4-yl-1,2,4-triazol-3-yl]sulfanyl]ethanone Chemical compound C=1C=CC=CC=1C(=O)CSC(N1CCC=2C=CC=CC=2)=NN=C1C1=CC=NC=C1 XNVSRSJSSNLZHI-UHFFFAOYSA-N 0.000 claims 1
• PVWFSMQYLPNHNC-UHFFFAOYSA-N 1-phenyl-2-[[5-phenyl-4-(2-phenylethyl)-1,2,4-triazol-3-yl]sulfanyl]ethanone Chemical compound C=1C=CC=CC=1C(=O)CSC(N1CCC=2C=CC=CC=2)=NN=C1C1=CC=CC=C1 PVWFSMQYLPNHNC-UHFFFAOYSA-N 0.000 claims 1
• XSMXFGNEKPFTES-UHFFFAOYSA-N 1-phenyl-N-[(4-phenyloxan-4-yl)methyl]cyclopentane-1-carboxamide Chemical compound C1CCCC1(C=1C=CC=CC=1)C(=O)NCC1(C=2C=CC=CC=2)CCOCC1 XSMXFGNEKPFTES-UHFFFAOYSA-N 0.000 claims 1
• NKMVIVBZSDPXIO-UHFFFAOYSA-N 1H-imidazol-5-yl-(3,3,5-trimethyl-7-azabicyclo[3.2.1]octan-7-yl)methanone Chemical compound C1C(C)(C)CC(C)(C2)CC1N2C(=O)C1=CNC=N1 NKMVIVBZSDPXIO-UHFFFAOYSA-N 0.000 claims 1
• RPUJVSJHGXHSGV-UHFFFAOYSA-N 1H-indol-2-yl-(3,3,5-trimethyl-7-azabicyclo[3.2.1]octan-7-yl)methanone Chemical compound C1=CC=C2NC(C(=O)N3C4CC(CC(C)(C)C4)(C3)C)=CC2=C1 RPUJVSJHGXHSGV-UHFFFAOYSA-N 0.000 claims 1
• RNBNCLUSOOUPDD-UHFFFAOYSA-N 1H-indol-3-yl-(3,3,5-trimethyl-7-azabicyclo[3.2.1]octan-7-yl)methanone Chemical compound C1=CC=C2C(C(=O)N3C4CC(CC(C)(C)C4)(C3)C)=CNC2=C1 RNBNCLUSOOUPDD-UHFFFAOYSA-N 0.000 claims 1
• ZDARYQBTTLXSAW-UHFFFAOYSA-N 1H-indol-4-yl(piperidin-1-yl)methanone Chemical compound C=1C=CC=2NC=CC=2C=1C(=O)N1CCCCC1 ZDARYQBTTLXSAW-UHFFFAOYSA-N 0.000 claims 1
• URZDFIWYIIBQNA-UHFFFAOYSA-N 1H-indol-5-yl-(3,3,5-trimethyl-7-azabicyclo[3.2.1]octan-7-yl)methanone Chemical compound C1=C2NC=CC2=CC(C(=O)N2C3CC(CC(C)(C)C3)(C2)C)=C1 URZDFIWYIIBQNA-UHFFFAOYSA-N 0.000 claims 1
• MQMVUBXPIHNHTG-UHFFFAOYSA-N 1H-indol-5-yl-(4-phenylpiperidin-1-yl)methanone Chemical compound C=1C=C2NC=CC2=CC=1C(=O)N(CC1)CCC1C1=CC=CC=C1 MQMVUBXPIHNHTG-UHFFFAOYSA-N 0.000 claims 1
• DIVUGLHALPBSGO-UHFFFAOYSA-N 1H-indol-5-yl-(4-pyrrolidin-1-ylpiperidin-1-yl)methanone Chemical compound C=1C=C2NC=CC2=CC=1C(=O)N(CC1)CCC1N1CCCC1 DIVUGLHALPBSGO-UHFFFAOYSA-N 0.000 claims 1
• MGXIIXQIKRNOLY-UHFFFAOYSA-N 1H-indol-6-yl-(3,3,5-trimethyl-7-azabicyclo[3.2.1]octan-7-yl)methanone Chemical compound C1=C2C=CNC2=CC(C(=O)N2C3CC(CC(C)(C)C3)(C2)C)=C1 MGXIIXQIKRNOLY-UHFFFAOYSA-N 0.000 claims 1
• YXELWVOQOFNVTK-UHFFFAOYSA-N 1H-indol-7-yl-(3,3,5-trimethyl-7-azabicyclo[3.2.1]octan-7-yl)methanone Chemical compound C1C(C)(C)CC(C)(C2)CC1N2C(=O)C1=CC=CC2=C1NC=C2 YXELWVOQOFNVTK-UHFFFAOYSA-N 0.000 claims 1
• IENZCGNHSIMFJE-UHFFFAOYSA-N 1H-indole-5-carboxylic acid Chemical compound OC(=O)C1=CC=C2NC=CC2=C1 IENZCGNHSIMFJE-UHFFFAOYSA-N 0.000 claims 1
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• GMMCOOOUDUJFSW-UHFFFAOYSA-N 2,2-dimethyl-N-(5-propyl-1,3,4-thiadiazol-2-yl)propanamide Chemical compound CCCC1=NN=C(NC(=O)C(C)(C)C)S1 GMMCOOOUDUJFSW-UHFFFAOYSA-N 0.000 claims 1
• DZLRDAUPHSQETM-UHFFFAOYSA-N 2,4-bis(phenylmethoxy)benzamide Chemical compound C1=C(OCC=2C=CC=CC=2)C(C(=O)N)=CC=C1OCC1=CC=CC=C1 DZLRDAUPHSQETM-UHFFFAOYSA-N 0.000 claims 1
• XOZFIDFWSRLTET-UHFFFAOYSA-N 2,4-dichloro-N-(3,3-dimethyl-1,5-dioxaspiro[5.5]undecan-9-yl)-N-methylbenzamide Chemical compound C=1C=C(Cl)C=C(Cl)C=1C(=O)N(C)C(CC1)CCC21OCC(C)(C)CO2 XOZFIDFWSRLTET-UHFFFAOYSA-N 0.000 claims 1
• XTHOLULPJKNCNL-UHFFFAOYSA-N 2,4-dichloro-N-[2-(furan-2-ylmethyl)cyclohexyl]benzamide Chemical compound ClC1=CC(Cl)=CC=C1C(=O)NC1C(CC=2OC=CC=2)CCCC1 XTHOLULPJKNCNL-UHFFFAOYSA-N 0.000 claims 1
• SYYLVEYCYAHMES-UHFFFAOYSA-N 2,4-dichloro-N-[3-(piperidine-1-carbonyl)phenyl]benzamide Chemical compound ClC1=CC(Cl)=CC=C1C(=O)NC1=CC=CC(C(=O)N2CCCCC2)=C1 SYYLVEYCYAHMES-UHFFFAOYSA-N 0.000 claims 1
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• XDMKZNARJRZIFT-UHFFFAOYSA-N 2,4-dichloro-N-methyl-N-(4-oxocyclohexyl)benzamide Chemical compound C=1C=C(Cl)C=C(Cl)C=1C(=O)N(C)C1CCC(=O)CC1 XDMKZNARJRZIFT-UHFFFAOYSA-N 0.000 claims 1
• SZZRVHTXVVVMLC-UHFFFAOYSA-N 2,6-difluoro-N-naphthalen-1-ylbenzamide Chemical compound FC1=CC=CC(F)=C1C(=O)NC1=CC=CC2=CC=CC=C12 SZZRVHTXVVVMLC-UHFFFAOYSA-N 0.000 claims 1
• HYHXZYUFKVAWAB-UHFFFAOYSA-N 2-(1,3-benzothiazol-2-ylsulfanyl)-N-(2,4,4-trimethylpentan-2-yl)acetamide Chemical compound C1=CC=C2SC(SCC(=O)NC(C)(C)CC(C)(C)C)=NC2=C1 HYHXZYUFKVAWAB-UHFFFAOYSA-N 0.000 claims 1
• SZZZTWMTNQPXKL-UHFFFAOYSA-N 2-(1,3-benzothiazol-2-ylsulfanyl)-N-cyclohexylacetamide Chemical compound N=1C2=CC=CC=C2SC=1SCC(=O)NC1CCCCC1 SZZZTWMTNQPXKL-UHFFFAOYSA-N 0.000 claims 1
• KTPJCOZKVMXEGK-UHFFFAOYSA-N 2-(1,3-benzoxazol-2-ylsulfanyl)-N-(2,4,4-trimethylpentan-2-yl)acetamide Chemical compound C1=CC=C2OC(SCC(=O)NC(C)(C)CC(C)(C)C)=NC2=C1 KTPJCOZKVMXEGK-UHFFFAOYSA-N 0.000 claims 1
• ZJNKJHQMNJRKGE-UHFFFAOYSA-N 2-(1,3-dioxoisoindol-2-yl)-3-methyl-N-[2-(trifluoromethyl)phenyl]butanamide Chemical compound O=C1C2=CC=CC=C2C(=O)N1C(C(C)C)C(=O)NC1=CC=CC=C1C(F)(F)F ZJNKJHQMNJRKGE-UHFFFAOYSA-N 0.000 claims 1
• CHJOWHPQUASBRL-UHFFFAOYSA-N 2-(1-adamantyl)-1-(3,4-dihydro-1H-isoquinolin-2-yl)ethanone Chemical compound C1CC2=CC=CC=C2CN1C(=O)CC1(C2)CC(C3)CC2CC3C1 CHJOWHPQUASBRL-UHFFFAOYSA-N 0.000 claims 1
• DEOYDVAGDKZVNR-UHFFFAOYSA-N 2-(1-adamantyl)-N-[1-(2,5-dimethylphenyl)ethyl]acetamide Chemical compound C1C(C2)CC(C3)CC2CC13CC(=O)NC(C)C1=CC(C)=CC=C1C DEOYDVAGDKZVNR-UHFFFAOYSA-N 0.000 claims 1
• ZGAFKODKTAZUCO-UHFFFAOYSA-N 2-(1-benzylimidazol-2-yl)sulfanyl-N-cyclohexylacetamide Chemical compound C1CCCCC1NC(=O)CSC1=NC=CN1CC1=CC=CC=C1 ZGAFKODKTAZUCO-UHFFFAOYSA-N 0.000 claims 1
• BPFIBMDESXSKSD-UHFFFAOYSA-N 2-(1-methylindol-3-yl)-1-(3,3,5-trimethyl-7-azabicyclo[3.2.1]octan-7-yl)ethanone Chemical compound C12=CC=CC=C2N(C)C=C1CC(=O)N1C(CC(C)(C)C2)CC2(C)C1 BPFIBMDESXSKSD-UHFFFAOYSA-N 0.000 claims 1
• ZZVHFDYCBPKARA-UHFFFAOYSA-N 2-(1H-indol-3-yl)-1-(3,3,5-trimethyl-7-azabicyclo[3.2.1]octan-7-yl)ethanone Chemical compound C1=CC=C2C(CC(=O)N3C4CC(CC(C)(C)C4)(C3)C)=CNC2=C1 ZZVHFDYCBPKARA-UHFFFAOYSA-N 0.000 claims 1
• BXRMUOJFVNNURK-UHFFFAOYSA-N 2-(2,4-dichlorophenoxy)-N-(2-methylbutyl)propanamide Chemical compound CCC(C)CNC(=O)C(C)OC1=CC=C(Cl)C=C1Cl BXRMUOJFVNNURK-UHFFFAOYSA-N 0.000 claims 1
• PYYAWGIWWYJBNR-UHFFFAOYSA-N 2-(2,4-dimethylphenoxy)-1-(6-fluoro-2-methyl-3,4-dihydro-2H-quinolin-1-yl)ethanone Chemical compound CC1CCC2=CC(F)=CC=C2N1C(=O)COC1=CC=C(C)C=C1C PYYAWGIWWYJBNR-UHFFFAOYSA-N 0.000 claims 1
• CHSYLCUXRJCXFN-UHFFFAOYSA-N 2-(2,6-dimethylphenoxy)-N-(2-propan-2-ylphenyl)acetamide Chemical compound CC(C)C1=CC=CC=C1NC(=O)COC1=C(C)C=CC=C1C CHSYLCUXRJCXFN-UHFFFAOYSA-N 0.000 claims 1
• VIGAKWPOIGTBHP-UHFFFAOYSA-N 2-(2-aminophenyl)sulfanyl-1-(5-fluoro-2,3-dihydroindol-1-yl)ethanone Chemical compound NC1=CC=CC=C1SCC(=O)N1C2=CC=C(F)C=C2CC1 VIGAKWPOIGTBHP-UHFFFAOYSA-N 0.000 claims 1
• QTDRMKNBWKWZAT-UHFFFAOYSA-N 2-(2-bromo-4-methylphenoxy)-N-[2-(cyclohexen-1-yl)ethyl]acetamide Chemical compound BrC1=CC(C)=CC=C1OCC(=O)NCCC1=CCCCC1 QTDRMKNBWKWZAT-UHFFFAOYSA-N 0.000 claims 1
• JBIMBKPZHTYYSV-UHFFFAOYSA-N 2-(2-cyanophenyl)sulfanyl-N-[2-(trifluoromethyl)phenyl]benzamide Chemical compound FC(F)(F)C1=CC=CC=C1NC(=O)C1=CC=CC=C1SC1=CC=CC=C1C#N JBIMBKPZHTYYSV-UHFFFAOYSA-N 0.000 claims 1
• RHIGPRNANIWPMK-UHFFFAOYSA-N 2-(2-cyanophenyl)sulfanyl-N-cyclopentylbenzamide Chemical compound C=1C=CC=C(SC=2C(=CC=CC=2)C#N)C=1C(=O)NC1CCCC1 RHIGPRNANIWPMK-UHFFFAOYSA-N 0.000 claims 1
• GYVNLDXQFZLUNN-UHFFFAOYSA-N 2-(2-ethylphenyl)sulfanyl-3-[methyl(2-pyridin-4-ylethyl)amino]-N-prop-2-ynylpropanamide Chemical compound CCC1=CC=CC=C1SC(C(=O)NCC#C)CN(C)CCC1=CC=NC=C1 GYVNLDXQFZLUNN-UHFFFAOYSA-N 0.000 claims 1
• XOBAUKAMJJYOQV-UHFFFAOYSA-N 2-(2-oxo-2-phenothiazin-10-ylethyl)-3a,4,5,6,7,7a-hexahydroisoindole-1,3-dione Chemical compound C12=CC=CC=C2SC2=CC=CC=C2N1C(=O)CN1C(=O)C2CCCCC2C1=O XOBAUKAMJJYOQV-UHFFFAOYSA-N 0.000 claims 1
• WINRQCKZGHXTHE-UHFFFAOYSA-N 2-(2-phenylethyl)-N-[2-(trifluoromethyl)phenyl]benzamide Chemical compound FC(F)(F)C1=CC=CC=C1NC(=O)C1=CC=CC=C1CCC1=CC=CC=C1 WINRQCKZGHXTHE-UHFFFAOYSA-N 0.000 claims 1
• FSBRTGBOSCGYHK-UHFFFAOYSA-N 2-(3,4-difluorophenyl)-N-[(4-hydroxyphenyl)methyl]-N-(thiophen-2-ylmethyl)acetamide Chemical compound C1=CC(O)=CC=C1CN(C(=O)CC=1C=C(F)C(F)=CC=1)CC1=CC=CS1 FSBRTGBOSCGYHK-UHFFFAOYSA-N 0.000 claims 1
• IMELXIOCAHSTMS-UHFFFAOYSA-N 2-(3-fluorophenyl)-N-[(4-hydroxyphenyl)methyl]-N-(4-methylhexan-2-yl)acetamide Chemical compound C=1C=CC(F)=CC=1CC(=O)N(C(C)CC(C)CC)CC1=CC=C(O)C=C1 IMELXIOCAHSTMS-UHFFFAOYSA-N 0.000 claims 1
• XGOIPSPRYYSFMC-UHFFFAOYSA-N 2-(3-oxo-3-phenylprop-1-enyl)isoindole-1,3-dione Chemical compound O=C1C2=CC=CC=C2C(=O)N1C=CC(=O)C1=CC=CC=C1 XGOIPSPRYYSFMC-UHFFFAOYSA-N 0.000 claims 1
• BWSOOJDEOGMMRQ-UHFFFAOYSA-N 2-(4-aminophenyl)-N-cyclohexyl-N-methyl-3H-benzimidazole-5-carboxamide Chemical compound C=1C=C2NC(C=3C=CC(N)=CC=3)=NC2=CC=1C(=O)N(C)C1CCCCC1 BWSOOJDEOGMMRQ-UHFFFAOYSA-N 0.000 claims 1
• NYEUXEWXWIOAAX-UHFFFAOYSA-N 2-(4-chloro-2-methylphenoxy)-N-[2-(trifluoromethyl)phenyl]propanamide Chemical compound C=1C=CC=C(C(F)(F)F)C=1NC(=O)C(C)OC1=CC=C(Cl)C=C1C NYEUXEWXWIOAAX-UHFFFAOYSA-N 0.000 claims 1
• BYNQYIFSLUHTNV-UHFFFAOYSA-N 2-(4-chloro-2-methylphenoxy)-N-cycloheptylacetamide Chemical compound CC1=CC(Cl)=CC=C1OCC(=O)NC1CCCCCC1 BYNQYIFSLUHTNV-UHFFFAOYSA-N 0.000 claims 1
• VGTHJTOHJMCXDJ-UHFFFAOYSA-N 2-(4-chloro-3-methylphenoxy)-N-cyclohexyl-N-methylacetamide Chemical compound C=1C=C(Cl)C(C)=CC=1OCC(=O)N(C)C1CCCCC1 VGTHJTOHJMCXDJ-UHFFFAOYSA-N 0.000 claims 1
• FOHQVDIHFKCOHQ-UHFFFAOYSA-N 2-(4-chlorophenoxy)-N-(2-fluoro-5-methylphenyl)-2-methylpropanamide Chemical compound CC1=CC=C(F)C(NC(=O)C(C)(C)OC=2C=CC(Cl)=CC=2)=C1 FOHQVDIHFKCOHQ-UHFFFAOYSA-N 0.000 claims 1
• KYADFMKHEIXPJH-UHFFFAOYSA-N 2-(4-chlorophenoxy)-N-[4-chloro-3-(trifluoromethyl)phenyl]acetamide Chemical compound C1=C(Cl)C(C(F)(F)F)=CC(NC(=O)COC=2C=CC(Cl)=CC=2)=C1 KYADFMKHEIXPJH-UHFFFAOYSA-N 0.000 claims 1
• KHSBCQTVHXXWOR-UHFFFAOYSA-N 2-(4-hydroxyphenyl)-N-[(2-hydroxyphenyl)methyl]-N-(2-methylpropyl)acetamide Chemical compound C=1C=C(O)C=CC=1CC(=O)N(CC(C)C)CC1=CC=CC=C1O KHSBCQTVHXXWOR-UHFFFAOYSA-N 0.000 claims 1
• DOURZFDBZLGWKZ-UHFFFAOYSA-N 2-(4-hydroxyphenyl)-N-[(3-hydroxyphenyl)methyl]-N-(4-methylpentyl)acetamide Chemical compound C=1C=C(O)C=CC=1CC(=O)N(CCCC(C)C)CC1=CC=CC(O)=C1 DOURZFDBZLGWKZ-UHFFFAOYSA-N 0.000 claims 1
• ZCTNFXZCSTURDF-UHFFFAOYSA-N 2-(4-hydroxyphenyl)-N-[(4-hydroxyphenyl)methyl]-N-(2-methylpropyl)acetamide Chemical compound C=1C=C(O)C=CC=1CC(=O)N(CC(C)C)CC1=CC=C(O)C=C1 ZCTNFXZCSTURDF-UHFFFAOYSA-N 0.000 claims 1
• MKNQAVLQSPCVCB-UHFFFAOYSA-N 2-(4-tert-butylphenoxy)-1-(4-ethylpiperazin-1-yl)ethanone Chemical compound C1CN(CC)CCN1C(=O)COC1=CC=C(C(C)(C)C)C=C1 MKNQAVLQSPCVCB-UHFFFAOYSA-N 0.000 claims 1
• NQYUAQXLGCYCTN-UHFFFAOYSA-N 2-(4-tert-butylphenoxy)-N-cyclooctylacetamide Chemical compound C1=CC(C(C)(C)C)=CC=C1OCC(=O)NC1CCCCCCC1 NQYUAQXLGCYCTN-UHFFFAOYSA-N 0.000 claims 1
• FYVCOFXRBWDYKD-UHFFFAOYSA-N 2-(6-oxo-6-piperidin-1-ylhexyl)isoindole-1,3-dione Chemical compound O=C1C2=CC=CC=C2C(=O)N1CCCCCC(=O)N1CCCCC1 FYVCOFXRBWDYKD-UHFFFAOYSA-N 0.000 claims 1
• HUIMOLNHHAFFEU-UHFFFAOYSA-N 2-(cyclohexylamino)-N-(1,2,3,4-tetrahydronaphthalen-1-yl)-1,3-thiazole-4-carboxamide Chemical compound C1CCC2=CC=CC=C2C1NC(=O)C(N=1)=CSC=1NC1CCCCC1 HUIMOLNHHAFFEU-UHFFFAOYSA-N 0.000 claims 1
• MWWOAZWEEHAJJX-UHFFFAOYSA-N 2-(cyclohexylamino)-N-(1-ethynylcyclohexyl)-1,3-thiazole-4-carboxamide Chemical compound C=1SC(NC2CCCCC2)=NC=1C(=O)NC1(C#C)CCCCC1 MWWOAZWEEHAJJX-UHFFFAOYSA-N 0.000 claims 1
• RQZWWNLSUYEWOE-UHFFFAOYSA-N 2-(cyclohexylamino)-N-(3-methylbutan-2-yl)-1,3-thiazole-4-carboxamide Chemical compound CC(C)C(C)NC(=O)C1=CSC(NC2CCCCC2)=N1 RQZWWNLSUYEWOE-UHFFFAOYSA-N 0.000 claims 1
• AALJBQNYQDCDMN-UHFFFAOYSA-N 2-(cyclohexylamino)-N-(4-hydroxycyclohexyl)-1,3-thiazole-4-carboxamide Chemical compound C1CC(O)CCC1NC(=O)C1=CSC(NC2CCCCC2)=N1 AALJBQNYQDCDMN-UHFFFAOYSA-N 0.000 claims 1
• IUSJOSOPIJDCMV-UHFFFAOYSA-N 2-(cyclohexylamino)-N-[2-(4-hydroxyphenyl)ethyl]-1,3-thiazole-4-carboxamide Chemical compound C1=CC(O)=CC=C1CCNC(=O)C1=CSC(NC2CCCCC2)=N1 IUSJOSOPIJDCMV-UHFFFAOYSA-N 0.000 claims 1
• ZQMPXFCWWNKNFB-UHFFFAOYSA-N 2-(cyclohexylamino)-N-[3-(1-hydroxyethyl)phenyl]-1,3-thiazole-4-carboxamide Chemical compound CC(O)C1=CC=CC(NC(=O)C=2N=C(NC3CCCCC3)SC=2)=C1 ZQMPXFCWWNKNFB-UHFFFAOYSA-N 0.000 claims 1
• AAHJNOMSGVULMS-UHFFFAOYSA-N 2-(cyclohexylamino)-N-pentan-3-yl-1,3-thiazole-4-carboxamide Chemical compound CCC(CC)NC(=O)C1=CSC(NC2CCCCC2)=N1 AAHJNOMSGVULMS-UHFFFAOYSA-N 0.000 claims 1
• JIBDQUYVHSTHGS-UHFFFAOYSA-N 2-(diethylamino)-N-[(1-phenylcyclopentyl)methyl]propanamide Chemical compound C=1C=CC=CC=1C1(CNC(=O)C(C)N(CC)CC)CCCC1 JIBDQUYVHSTHGS-UHFFFAOYSA-N 0.000 claims 1
• QMFWWRKULSMUSH-UHFFFAOYSA-N 2-(heptylcarbamoyl)bicyclo[2.2.1]hept-5-ene-3-carboxylic acid Chemical compound C1C2C=CC1C(C(=O)NCCCCCCC)C2C(O)=O QMFWWRKULSMUSH-UHFFFAOYSA-N 0.000 claims 1
• PJVLHKQTZLLMDV-UHFFFAOYSA-N 2-(hexylamino)-N-[(4-hydroxyphenyl)methyl]-N-methylacetamide Chemical compound CCCCCCNCC(=O)N(C)CC1=CC=C(O)C=C1 PJVLHKQTZLLMDV-UHFFFAOYSA-N 0.000 claims 1
• SJUHYWWBQFWWQS-UHFFFAOYSA-N 2-(piperidine-1-carbonyl)-5-piperidin-1-yl-1,3-oxazole-4-carbonitrile Chemical compound N=1C(C#N)=C(N2CCCCC2)OC=1C(=O)N1CCCCC1 SJUHYWWBQFWWQS-UHFFFAOYSA-N 0.000 claims 1
• ZDZWYBQALASASL-UHFFFAOYSA-N 2-(tert-butylamino)-1-[3-(4-methylphenyl)-1-adamantyl]ethanone Chemical compound C1=CC(C)=CC=C1C1(C2)CC(C3)(C(=O)CNC(C)(C)C)CC2CC3C1 ZDZWYBQALASASL-UHFFFAOYSA-N 0.000 claims 1
• DPEZMUJHPZIRQS-UHFFFAOYSA-N 2-[(2,6-difluorophenyl)methylamino]-N-[2-[3-(trifluoromethyl)phenyl]ethyl]acetamide Chemical compound FC1=CC=CC(F)=C1CNCC(=O)NCCC1=CC=CC(C(F)(F)F)=C1 DPEZMUJHPZIRQS-UHFFFAOYSA-N 0.000 claims 1
• GRCSGDXAMFCVSH-UHFFFAOYSA-N 2-[(2-amino-2-oxoethyl)-[3-methoxy-5-(pyridine-2-carbonyl)benzoyl]amino]acetic acid Chemical compound COC1=CC(C(=O)N(CC(N)=O)CC(O)=O)=CC(C(=O)C=2N=CC=CC=2)=C1 GRCSGDXAMFCVSH-UHFFFAOYSA-N 0.000 claims 1
• ZBOQEIHWWSHQTC-UHFFFAOYSA-N 2-[(2-benzylsulfanylacetyl)-(2-methoxyethyl)amino]-N-[2-[(2-chloro-6-fluorophenyl)methylsulfanyl]ethyl]acetamide Chemical compound C=1C=CC=CC=1CSCC(=O)N(CCOC)CC(=O)NCCSCC1=C(F)C=CC=C1Cl ZBOQEIHWWSHQTC-UHFFFAOYSA-N 0.000 claims 1
• NHEHDFPGKKPRFX-UHFFFAOYSA-N 2-[(2-methylphenyl)methylsulfanyl]-1-(4-phenylpiperazin-1-yl)ethanone Chemical compound CC1=CC=CC=C1CSCC(=O)N1CCN(C=2C=CC=CC=2)CC1 NHEHDFPGKKPRFX-UHFFFAOYSA-N 0.000 claims 1
• ZSSONPIPZWGZFV-UHFFFAOYSA-N 2-[(3-bromophenyl)methylsulfanyl]-1-(4-phenylpiperazin-1-yl)ethanone Chemical compound BrC1=CC=CC(CSCC(=O)N2CCN(CC2)C=2C=CC=CC=2)=C1 ZSSONPIPZWGZFV-UHFFFAOYSA-N 0.000 claims 1
• OZWBTJRHLDARMF-UHFFFAOYSA-N 2-[(3-bromophenyl)methylsulfanyl]-1-[4-(2-methoxyphenyl)piperazin-1-yl]ethanone Chemical compound COC1=CC=CC=C1N1CCN(C(=O)CSCC=2C=C(Br)C=CC=2)CC1 OZWBTJRHLDARMF-UHFFFAOYSA-N 0.000 claims 1
• YUYYOUDVNNTGBH-UHFFFAOYSA-N 2-[(3-bromophenyl)methylsulfanyl]-1-piperidin-1-ylethanone Chemical compound BrC1=CC=CC(CSCC(=O)N2CCCCC2)=C1 YUYYOUDVNNTGBH-UHFFFAOYSA-N 0.000 claims 1
• PXFCPVKUQUIYBH-UHFFFAOYSA-N 2-[(4,5-dibenzyl-1,2,4-triazol-3-yl)sulfanyl]-N-(1,3-thiazol-2-yl)acetamide Chemical compound N=1C=CSC=1NC(=O)CSC(N1CC=2C=CC=CC=2)=NN=C1CC1=CC=CC=C1 PXFCPVKUQUIYBH-UHFFFAOYSA-N 0.000 claims 1
• JPQYHLMHOCTCRD-UHFFFAOYSA-N 2-[(4,5-dibenzyl-1,2,4-triazol-3-yl)sulfanyl]-N-(4-nitrophenyl)acetamide Chemical compound C1=CC([N+](=O)[O-])=CC=C1NC(=O)CSC(N1CC=2C=CC=CC=2)=NN=C1CC1=CC=CC=C1 JPQYHLMHOCTCRD-UHFFFAOYSA-N 0.000 claims 1
• CAMRZLGQEARZNA-UHFFFAOYSA-N 2-[(4-benzyl-5-methyl-1,2,4-triazol-3-yl)sulfanyl]-1-phenylethanone Chemical compound C=1C=CC=CC=1CN1C(C)=NN=C1SCC(=O)C1=CC=CC=C1 CAMRZLGQEARZNA-UHFFFAOYSA-N 0.000 claims 1
• LBAJRNIKSGBRKY-UHFFFAOYSA-N 2-[(4-benzyl-5-phenyl-1,2,4-triazol-3-yl)sulfanyl]-N-(1,3-thiazol-2-yl)acetamide Chemical compound N=1C=CSC=1NC(=O)CSC(N1CC=2C=CC=CC=2)=NN=C1C1=CC=CC=C1 LBAJRNIKSGBRKY-UHFFFAOYSA-N 0.000 claims 1
• AAVBZIRJRXJTRJ-UHFFFAOYSA-N 2-[(4-benzyl-5-phenyl-1,2,4-triazol-3-yl)sulfanyl]-N-(2-nitrophenyl)acetamide Chemical compound [O-][N+](=O)C1=CC=CC=C1NC(=O)CSC(N1CC=2C=CC=CC=2)=NN=C1C1=CC=CC=C1 AAVBZIRJRXJTRJ-UHFFFAOYSA-N 0.000 claims 1
• NMDMRHKNAHCKIN-UHFFFAOYSA-N 2-[(4-benzyl-5-phenyl-1,2,4-triazol-3-yl)sulfanyl]-N-(4-methoxy-2-nitrophenyl)acetamide Chemical compound [O-][N+](=O)C1=CC(OC)=CC=C1NC(=O)CSC(N1CC=2C=CC=CC=2)=NN=C1C1=CC=CC=C1 NMDMRHKNAHCKIN-UHFFFAOYSA-N 0.000 claims 1
• UCVZELOSGRELQR-UHFFFAOYSA-N 2-[(4-benzyl-5-phenyl-1,2,4-triazol-3-yl)sulfanyl]-N-(5-methyl-1,3-thiazol-2-yl)acetamide Chemical compound S1C(C)=CN=C1NC(=O)CSC(N1CC=2C=CC=CC=2)=NN=C1C1=CC=CC=C1 UCVZELOSGRELQR-UHFFFAOYSA-N 0.000 claims 1
• XYICGIWIAUBMFT-UHFFFAOYSA-N 2-[(4-benzyl-5-pyridin-3-yl-1,2,4-triazol-3-yl)sulfanyl]-N-(2,4-dimethylphenyl)acetamide Chemical compound CC1=CC(C)=CC=C1NC(=O)CSC(N1CC=2C=CC=CC=2)=NN=C1C1=CC=CN=C1 XYICGIWIAUBMFT-UHFFFAOYSA-N 0.000 claims 1
• NTRXTQXPZGPAEP-UHFFFAOYSA-N 2-[(4-benzyl-5-pyridin-3-yl-1,2,4-triazol-3-yl)sulfanyl]-N-(2,5-dichlorophenyl)acetamide Chemical compound ClC1=CC=C(Cl)C(NC(=O)CSC=2N(C(C=3C=NC=CC=3)=NN=2)CC=2C=CC=CC=2)=C1 NTRXTQXPZGPAEP-UHFFFAOYSA-N 0.000 claims 1
• ZHCMLMMMHDUQAK-UHFFFAOYSA-N 2-[(4-benzyl-5-pyridin-3-yl-1,2,4-triazol-3-yl)sulfanyl]-N-(2-chlorophenyl)acetamide Chemical compound ClC1=CC=CC=C1NC(=O)CSC(N1CC=2C=CC=CC=2)=NN=C1C1=CC=CN=C1 ZHCMLMMMHDUQAK-UHFFFAOYSA-N 0.000 claims 1
• BOHGBGJEZYUOGV-UHFFFAOYSA-N 2-[(4-benzyl-5-pyridin-3-yl-1,2,4-triazol-3-yl)sulfanyl]-N-(3-chloro-4-methylphenyl)acetamide Chemical compound C1=C(Cl)C(C)=CC=C1NC(=O)CSC(N1CC=2C=CC=CC=2)=NN=C1C1=CC=CN=C1 BOHGBGJEZYUOGV-UHFFFAOYSA-N 0.000 claims 1
• RXEQJKYCIPBBON-UHFFFAOYSA-N 2-[(4-benzyl-5-pyridin-3-yl-1,2,4-triazol-3-yl)sulfanyl]-N-(3-chlorophenyl)acetamide Chemical compound ClC1=CC=CC(NC(=O)CSC=2N(C(C=3C=NC=CC=3)=NN=2)CC=2C=CC=CC=2)=C1 RXEQJKYCIPBBON-UHFFFAOYSA-N 0.000 claims 1
• KGKIVMCUBOBICZ-UHFFFAOYSA-N 2-[(4-benzyl-5-pyridin-3-yl-1,2,4-triazol-3-yl)sulfanyl]-N-(4-fluorophenyl)acetamide Chemical compound C1=CC(F)=CC=C1NC(=O)CSC(N1CC=2C=CC=CC=2)=NN=C1C1=CC=CN=C1 KGKIVMCUBOBICZ-UHFFFAOYSA-N 0.000 claims 1
• HMPMXRWESNIDBX-UHFFFAOYSA-N 2-[(4-benzyl-5-pyridin-3-yl-1,2,4-triazol-3-yl)sulfanyl]-N-(4-methoxyphenyl)acetamide Chemical compound C1=CC(OC)=CC=C1NC(=O)CSC(N1CC=2C=CC=CC=2)=NN=C1C1=CC=CN=C1 HMPMXRWESNIDBX-UHFFFAOYSA-N 0.000 claims 1
• WYYUHUCKFFEZGC-UHFFFAOYSA-N 2-[(4-benzyl-5-pyridin-3-yl-1,2,4-triazol-3-yl)sulfanyl]-N-(4-nitrophenyl)acetamide Chemical compound C1=CC([N+](=O)[O-])=CC=C1NC(=O)CSC(N1CC=2C=CC=CC=2)=NN=C1C1=CC=CN=C1 WYYUHUCKFFEZGC-UHFFFAOYSA-N 0.000 claims 1
• MALAUNNEZDDMRB-UHFFFAOYSA-N 2-[(4-benzyl-5-pyridin-3-yl-1,2,4-triazol-3-yl)sulfanyl]-N-(4-nitrophenyl)propanamide Chemical compound C=1C=C([N+]([O-])=O)C=CC=1NC(=O)C(C)SC(N1CC=2C=CC=CC=2)=NN=C1C1=CC=CN=C1 MALAUNNEZDDMRB-UHFFFAOYSA-N 0.000 claims 1
• KHAWECWHKUKBNB-UHFFFAOYSA-N 2-[(4-benzyl-5-pyridin-3-yl-1,2,4-triazol-3-yl)sulfanyl]-N-(5-ethyl-1,3,4-thiadiazol-2-yl)acetamide Chemical compound S1C(CC)=NN=C1NC(=O)CSC(N1CC=2C=CC=CC=2)=NN=C1C1=CC=CN=C1 KHAWECWHKUKBNB-UHFFFAOYSA-N 0.000 claims 1
• MSNONISGFCZKJO-UHFFFAOYSA-N 2-[(4-benzyl-5-pyridin-3-yl-1,2,4-triazol-3-yl)sulfanyl]-N-phenylacetamide Chemical compound C=1C=CC=CC=1NC(=O)CSC(N1CC=2C=CC=CC=2)=NN=C1C1=CC=CN=C1 MSNONISGFCZKJO-UHFFFAOYSA-N 0.000 claims 1
• DWGCUVVVRGHFLS-UHFFFAOYSA-N 2-[(4-cyclopropyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanylmethyl]benzonitrile Chemical compound N#CC1=CC=CC=C1CSC(N1C2CC2)=NN=C1C1=CC=CS1 DWGCUVVVRGHFLS-UHFFFAOYSA-N 0.000 claims 1
• FIRTVNRJWCZONW-UHFFFAOYSA-N 2-[(4-cyclopropyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanylmethyl]pyridine Chemical compound C=1C=CC=NC=1CSC(N1C2CC2)=NN=C1C1=CC=CS1 FIRTVNRJWCZONW-UHFFFAOYSA-N 0.000 claims 1
• IZEIJCICDFBHJZ-UHFFFAOYSA-N 2-[(4-ethyl-5-phenyl-1,2,4-triazol-3-yl)sulfanyl]-1-(4-methoxyphenyl)ethanone Chemical compound N=1N=C(C=2C=CC=CC=2)N(CC)C=1SCC(=O)C1=CC=C(OC)C=C1 IZEIJCICDFBHJZ-UHFFFAOYSA-N 0.000 claims 1
• YDXZAZIBEPHVBH-UHFFFAOYSA-N 2-[(4-ethyl-5-phenyl-1,2,4-triazol-3-yl)sulfanyl]-1-(4-methylphenyl)ethanone Chemical compound N=1N=C(C=2C=CC=CC=2)N(CC)C=1SCC(=O)C1=CC=C(C)C=C1 YDXZAZIBEPHVBH-UHFFFAOYSA-N 0.000 claims 1
• VQZXMZKKRCWFEH-UHFFFAOYSA-N 2-[(4-ethyl-5-phenyl-1,2,4-triazol-3-yl)sulfanyl]-1-(4-methylsulfonylphenyl)ethanone Chemical compound N=1N=C(C=2C=CC=CC=2)N(CC)C=1SCC(=O)C1=CC=C(S(C)(=O)=O)C=C1 VQZXMZKKRCWFEH-UHFFFAOYSA-N 0.000 claims 1
• NYRMEOIXCWFRCR-UHFFFAOYSA-N 2-[(4-ethyl-5-phenyl-1,2,4-triazol-3-yl)sulfanyl]-1-pyridin-3-ylethanone Chemical compound N=1N=C(C=2C=CC=CC=2)N(CC)C=1SCC(=O)C1=CC=CN=C1 NYRMEOIXCWFRCR-UHFFFAOYSA-N 0.000 claims 1
• COPOUVWMGZKHBX-UHFFFAOYSA-N 2-[(4-ethyl-5-phenyl-1,2,4-triazol-3-yl)sulfanyl]-N-(1,3-thiazol-2-yl)acetamide Chemical compound N=1N=C(C=2C=CC=CC=2)N(CC)C=1SCC(=O)NC1=NC=CS1 COPOUVWMGZKHBX-UHFFFAOYSA-N 0.000 claims 1
• XXXVUIMIIDCHLC-UHFFFAOYSA-N 2-[(4-ethyl-5-phenyl-1,2,4-triazol-3-yl)sulfanyl]-N-(2-methoxy-4-nitrophenyl)acetamide Chemical compound N=1N=C(C=2C=CC=CC=2)N(CC)C=1SCC(=O)NC1=CC=C([N+]([O-])=O)C=C1OC XXXVUIMIIDCHLC-UHFFFAOYSA-N 0.000 claims 1
• HHDUWNVUOSHJCQ-UHFFFAOYSA-N 2-[(4-ethyl-5-phenyl-1,2,4-triazol-3-yl)sulfanyl]-N-(2-methoxyphenyl)acetamide Chemical compound N=1N=C(C=2C=CC=CC=2)N(CC)C=1SCC(=O)NC1=CC=CC=C1OC HHDUWNVUOSHJCQ-UHFFFAOYSA-N 0.000 claims 1
• HRCZOOXRIROALG-UHFFFAOYSA-N 2-[(4-ethyl-5-phenyl-1,2,4-triazol-3-yl)sulfanyl]-N-(2-methyl-4-nitrophenyl)acetamide Chemical compound N=1N=C(C=2C=CC=CC=2)N(CC)C=1SCC(=O)NC1=CC=C([N+]([O-])=O)C=C1C HRCZOOXRIROALG-UHFFFAOYSA-N 0.000 claims 1
• HSYYQEYXSAOILU-UHFFFAOYSA-N 2-[(4-ethyl-5-phenyl-1,2,4-triazol-3-yl)sulfanyl]-N-(2-nitrophenyl)acetamide Chemical compound N=1N=C(C=2C=CC=CC=2)N(CC)C=1SCC(=O)NC1=CC=CC=C1[N+]([O-])=O HSYYQEYXSAOILU-UHFFFAOYSA-N 0.000 claims 1
• GWDQNILHJYBECH-UHFFFAOYSA-N 2-[(4-ethyl-5-phenyl-1,2,4-triazol-3-yl)sulfanyl]-N-(2-phenylphenyl)acetamide Chemical compound N=1N=C(C=2C=CC=CC=2)N(CC)C=1SCC(=O)NC1=CC=CC=C1C1=CC=CC=C1 GWDQNILHJYBECH-UHFFFAOYSA-N 0.000 claims 1
• ZQHHQRSCAFOVKR-UHFFFAOYSA-N 2-[(4-ethyl-5-phenyl-1,2,4-triazol-3-yl)sulfanyl]-N-(4-fluorophenyl)acetamide Chemical compound N=1N=C(C=2C=CC=CC=2)N(CC)C=1SCC(=O)NC1=CC=C(F)C=C1 ZQHHQRSCAFOVKR-UHFFFAOYSA-N 0.000 claims 1
• KLDXTEQXASFNGL-UHFFFAOYSA-N 2-[(4-ethyl-5-phenyl-1,2,4-triazol-3-yl)sulfanyl]-N-[2-(trifluoromethyl)phenyl]acetamide Chemical compound N=1N=C(C=2C=CC=CC=2)N(CC)C=1SCC(=O)NC1=CC=CC=C1C(F)(F)F KLDXTEQXASFNGL-UHFFFAOYSA-N 0.000 claims 1
• AOYSFQOMUDJRNG-UHFFFAOYSA-N 2-[(4-ethyl-5-pyridin-3-yl-1,2,4-triazol-3-yl)sulfanyl]-N,N-diphenylpropanamide Chemical compound N=1N=C(C=2C=NC=CC=2)N(CC)C=1SC(C)C(=O)N(C=1C=CC=CC=1)C1=CC=CC=C1 AOYSFQOMUDJRNG-UHFFFAOYSA-N 0.000 claims 1
• ZLHJBWWTEFXITQ-UHFFFAOYSA-N 2-[(4-ethyl-5-pyridin-4-yl-1,2,4-triazol-3-yl)sulfanyl]-1-(4-methoxyphenyl)ethanone Chemical compound N=1N=C(C=2C=CN=CC=2)N(CC)C=1SCC(=O)C1=CC=C(OC)C=C1 ZLHJBWWTEFXITQ-UHFFFAOYSA-N 0.000 claims 1
• YLNNBXZYUULBOF-UHFFFAOYSA-N 2-[(4-ethyl-5-pyridin-4-yl-1,2,4-triazol-3-yl)sulfanyl]-1-(4-methylsulfonylphenyl)ethanone Chemical compound N=1N=C(C=2C=CN=CC=2)N(CC)C=1SCC(=O)C1=CC=C(S(C)(=O)=O)C=C1 YLNNBXZYUULBOF-UHFFFAOYSA-N 0.000 claims 1
• WHFGTWKZLDSSNT-UHFFFAOYSA-N 2-[(4-ethyl-5-pyridin-4-yl-1,2,4-triazol-3-yl)sulfanyl]-1-phenylethanone Chemical compound N=1N=C(C=2C=CN=CC=2)N(CC)C=1SCC(=O)C1=CC=CC=C1 WHFGTWKZLDSSNT-UHFFFAOYSA-N 0.000 claims 1
• SQIIVHOIAJVGMN-UHFFFAOYSA-N 2-[(4-ethyl-5-pyridin-4-yl-1,2,4-triazol-3-yl)sulfanyl]-1-pyridin-3-ylethanone Chemical compound N=1N=C(C=2C=CN=CC=2)N(CC)C=1SCC(=O)C1=CC=CN=C1 SQIIVHOIAJVGMN-UHFFFAOYSA-N 0.000 claims 1
• YDTFZPVMKCIURQ-UHFFFAOYSA-N 2-[(4-methyl-5-phenacylsulfanyl-1,2,4-triazol-3-yl)methyl]-4H-1,4-benzothiazin-3-one Chemical compound CN1C(CC2C(NC3=CC=CC=C3S2)=O)=NN=C1SCC(=O)C1=CC=CC=C1 YDTFZPVMKCIURQ-UHFFFAOYSA-N 0.000 claims 1
• OMLATOXNVQCZBD-UHFFFAOYSA-N 2-[(4-methyl-5-phenyl-1,2,4-triazol-3-yl)sulfanyl]-1-phenylethanone Chemical compound N=1N=C(C=2C=CC=CC=2)N(C)C=1SCC(=O)C1=CC=CC=C1 OMLATOXNVQCZBD-UHFFFAOYSA-N 0.000 claims 1
• WNMCGLNHMAPWMX-UHFFFAOYSA-N 2-[(4-methyl-5-phenyl-1,2,4-triazol-3-yl)sulfanyl]-N-(1,3-thiazol-2-yl)acetamide Chemical compound N=1N=C(C=2C=CC=CC=2)N(C)C=1SCC(=O)NC1=NC=CS1 WNMCGLNHMAPWMX-UHFFFAOYSA-N 0.000 claims 1
• DJHQDEYOSLJOLU-UHFFFAOYSA-N 2-[(4-methylphenyl)methylsulfanyl]-1-piperidin-1-ylethanone Chemical compound C1=CC(C)=CC=C1CSCC(=O)N1CCCCC1 DJHQDEYOSLJOLU-UHFFFAOYSA-N 0.000 claims 1
• RCUQXNIZNQXWHL-UHFFFAOYSA-N 2-[(5,6-dimethyl-4-oxo-3H-thieno[2,3-d]pyrimidin-2-yl)sulfanyl]-N-(furan-2-ylmethyl)acetamide Chemical compound N1C(=O)C=2C(C)=C(C)SC=2N=C1SCC(=O)NCC1=CC=CO1 RCUQXNIZNQXWHL-UHFFFAOYSA-N 0.000 claims 1
• CBVQLFRFSZOZJB-UHFFFAOYSA-N 2-[(5-benzyl-4-ethyl-1,2,4-triazol-3-yl)sulfanyl]-1-(4-methoxyphenyl)ethanone Chemical compound N=1N=C(SCC(=O)C=2C=CC(OC)=CC=2)N(CC)C=1CC1=CC=CC=C1 CBVQLFRFSZOZJB-UHFFFAOYSA-N 0.000 claims 1
• LJRGXZXJRYSIEN-UHFFFAOYSA-N 2-[(5-benzyl-4-ethyl-1,2,4-triazol-3-yl)sulfanyl]-N-(2-bromo-4-methylphenyl)acetamide Chemical compound N=1N=C(SCC(=O)NC=2C(=CC(C)=CC=2)Br)N(CC)C=1CC1=CC=CC=C1 LJRGXZXJRYSIEN-UHFFFAOYSA-N 0.000 claims 1
• MWSZUKAKMYRTLW-UHFFFAOYSA-N 2-[(5-benzyl-4-ethyl-1,2,4-triazol-3-yl)sulfanyl]-N-(2-chlorophenyl)acetamide Chemical compound N=1N=C(SCC(=O)NC=2C(=CC=CC=2)Cl)N(CC)C=1CC1=CC=CC=C1 MWSZUKAKMYRTLW-UHFFFAOYSA-N 0.000 claims 1
• VKDGBSZGTHCTJW-UHFFFAOYSA-N 2-[(5-benzyl-4-ethyl-1,2,4-triazol-3-yl)sulfanyl]-N-(2-methoxy-4-nitrophenyl)acetamide Chemical compound N=1N=C(SCC(=O)NC=2C(=CC(=CC=2)[N+]([O-])=O)OC)N(CC)C=1CC1=CC=CC=C1 VKDGBSZGTHCTJW-UHFFFAOYSA-N 0.000 claims 1
• OIFGDCZYGQDBGD-UHFFFAOYSA-N 2-[(5-benzyl-4-ethyl-1,2,4-triazol-3-yl)sulfanyl]-N-(2-methyl-4-nitrophenyl)acetamide Chemical compound N=1N=C(SCC(=O)NC=2C(=CC(=CC=2)[N+]([O-])=O)C)N(CC)C=1CC1=CC=CC=C1 OIFGDCZYGQDBGD-UHFFFAOYSA-N 0.000 claims 1
• LXUKLKRRKKKBBS-UHFFFAOYSA-N 2-[(5-benzyl-4-ethyl-1,2,4-triazol-3-yl)sulfanyl]-N-(3-chloro-2-methylphenyl)acetamide Chemical compound N=1N=C(SCC(=O)NC=2C(=C(Cl)C=CC=2)C)N(CC)C=1CC1=CC=CC=C1 LXUKLKRRKKKBBS-UHFFFAOYSA-N 0.000 claims 1
• COZFFPUXXWBNCN-UHFFFAOYSA-N 2-[(5-benzyl-4-ethyl-1,2,4-triazol-3-yl)sulfanyl]-N-(4-bromophenyl)acetamide Chemical compound N=1N=C(SCC(=O)NC=2C=CC(Br)=CC=2)N(CC)C=1CC1=CC=CC=C1 COZFFPUXXWBNCN-UHFFFAOYSA-N 0.000 claims 1
• WGLDXNACFBBKRB-UHFFFAOYSA-N 2-[(5-benzyl-4-ethyl-1,2,4-triazol-3-yl)sulfanyl]-N-(4-chloro-3-nitrophenyl)acetamide Chemical compound N=1N=C(SCC(=O)NC=2C=C(C(Cl)=CC=2)[N+]([O-])=O)N(CC)C=1CC1=CC=CC=C1 WGLDXNACFBBKRB-UHFFFAOYSA-N 0.000 claims 1
• ZQVLGOHYAIFHDM-UHFFFAOYSA-N 2-[(5-benzyl-4-ethyl-1,2,4-triazol-3-yl)sulfanyl]-N-(4-ethylphenyl)acetamide Chemical compound C1=CC(CC)=CC=C1NC(=O)CSC(N1CC)=NN=C1CC1=CC=CC=C1 ZQVLGOHYAIFHDM-UHFFFAOYSA-N 0.000 claims 1
• JZKHALMWMRFZDX-UHFFFAOYSA-N 2-[(5-benzyl-4-ethyl-1,2,4-triazol-3-yl)sulfanyl]-N-(4-fluorophenyl)acetamide Chemical compound N=1N=C(SCC(=O)NC=2C=CC(F)=CC=2)N(CC)C=1CC1=CC=CC=C1 JZKHALMWMRFZDX-UHFFFAOYSA-N 0.000 claims 1
• NSKQZRLLDFIAMR-UHFFFAOYSA-N 2-[(5-benzyl-4-ethyl-1,2,4-triazol-3-yl)sulfanyl]-N-(4-methoxyphenyl)acetamide Chemical compound N=1N=C(SCC(=O)NC=2C=CC(OC)=CC=2)N(CC)C=1CC1=CC=CC=C1 NSKQZRLLDFIAMR-UHFFFAOYSA-N 0.000 claims 1
• CIRKKMVEODCIGM-UHFFFAOYSA-N 2-[(5-benzyl-4-ethyl-1,2,4-triazol-3-yl)sulfanyl]-N-(4-methyl-3-nitrophenyl)acetamide Chemical compound N=1N=C(SCC(=O)NC=2C=C(C(C)=CC=2)[N+]([O-])=O)N(CC)C=1CC1=CC=CC=C1 CIRKKMVEODCIGM-UHFFFAOYSA-N 0.000 claims 1
• JLXMMQVBTYKLIE-UHFFFAOYSA-N 2-[(5-benzyl-4-ethyl-1,2,4-triazol-3-yl)sulfanyl]-N-(4-nitrophenyl)acetamide Chemical compound N=1N=C(SCC(=O)NC=2C=CC(=CC=2)[N+]([O-])=O)N(CC)C=1CC1=CC=CC=C1 JLXMMQVBTYKLIE-UHFFFAOYSA-N 0.000 claims 1
• IWLQACYNQSZNSF-UHFFFAOYSA-N 2-[(5-benzyl-4-ethyl-1,2,4-triazol-3-yl)sulfanyl]-N-(5-ethyl-1,3,4-thiadiazol-2-yl)acetamide Chemical compound S1C(CC)=NN=C1NC(=O)CSC(N1CC)=NN=C1CC1=CC=CC=C1 IWLQACYNQSZNSF-UHFFFAOYSA-N 0.000 claims 1
• IVHLDCBGHULXFL-UHFFFAOYSA-N 2-[(5-benzyl-4-ethyl-1,2,4-triazol-3-yl)sulfanyl]-N-[2-(trifluoromethyl)phenyl]acetamide Chemical compound N=1N=C(SCC(=O)NC=2C(=CC=CC=2)C(F)(F)F)N(CC)C=1CC1=CC=CC=C1 IVHLDCBGHULXFL-UHFFFAOYSA-N 0.000 claims 1
• RSZFJCOIBSAZKN-UHFFFAOYSA-N 2-[(5-benzyl-4-ethyl-1,2,4-triazol-3-yl)sulfanyl]-N-phenylacetamide Chemical compound N=1N=C(SCC(=O)NC=2C=CC=CC=2)N(CC)C=1CC1=CC=CC=C1 RSZFJCOIBSAZKN-UHFFFAOYSA-N 0.000 claims 1
• PBFPARZCOASPBZ-UHFFFAOYSA-N 2-[(5-benzyl-4-methyl-1,2,4-triazol-3-yl)sulfanyl]-1-(3,4-dihydro-2H-quinolin-1-yl)ethanone Chemical compound N=1N=C(SCC(=O)N2C3=CC=CC=C3CCC2)N(C)C=1CC1=CC=CC=C1 PBFPARZCOASPBZ-UHFFFAOYSA-N 0.000 claims 1
• FCTPVQPOXUISFD-UHFFFAOYSA-N 2-[(5-benzyl-4-methyl-1,2,4-triazol-3-yl)sulfanyl]-1-(4-methylphenyl)ethanone Chemical compound C1=CC(C)=CC=C1C(=O)CSC(N1C)=NN=C1CC1=CC=CC=C1 FCTPVQPOXUISFD-UHFFFAOYSA-N 0.000 claims 1
• RCEFWFLUWHELRI-UHFFFAOYSA-N 2-[(5-benzyl-4-methyl-1,2,4-triazol-3-yl)sulfanyl]-1-phenylethanone Chemical compound N=1N=C(SCC(=O)C=2C=CC=CC=2)N(C)C=1CC1=CC=CC=C1 RCEFWFLUWHELRI-UHFFFAOYSA-N 0.000 claims 1
• MHMBYEPWGYLVPR-UHFFFAOYSA-N 2-[(5-benzyl-4-methyl-1,2,4-triazol-3-yl)sulfanyl]-N-(2-bromo-4-methylphenyl)acetamide Chemical compound BrC1=CC(C)=CC=C1NC(=O)CSC(N1C)=NN=C1CC1=CC=CC=C1 MHMBYEPWGYLVPR-UHFFFAOYSA-N 0.000 claims 1
• XXFINZOWWNSDAW-UHFFFAOYSA-N 2-[(5-benzyl-4-methyl-1,2,4-triazol-3-yl)sulfanyl]-N-(2-nitrophenyl)acetamide Chemical compound N=1N=C(SCC(=O)NC=2C(=CC=CC=2)[N+]([O-])=O)N(C)C=1CC1=CC=CC=C1 XXFINZOWWNSDAW-UHFFFAOYSA-N 0.000 claims 1
• JRGRZUDIEJDCHB-UHFFFAOYSA-N 2-[(5-benzyl-4-methyl-1,2,4-triazol-3-yl)sulfanyl]-N-(3-cyano-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)acetamide Chemical compound N=1N=C(SCC(=O)NC2=C(C=3CCCCC=3S2)C#N)N(C)C=1CC1=CC=CC=C1 JRGRZUDIEJDCHB-UHFFFAOYSA-N 0.000 claims 1
• KICJYMHLPJCPQH-UHFFFAOYSA-N 2-[(5-benzyl-4-methyl-1,2,4-triazol-3-yl)sulfanyl]-N-(4-bromophenyl)acetamide Chemical compound N=1N=C(SCC(=O)NC=2C=CC(Br)=CC=2)N(C)C=1CC1=CC=CC=C1 KICJYMHLPJCPQH-UHFFFAOYSA-N 0.000 claims 1
• WAJKAVZEYXRYGS-UHFFFAOYSA-N 2-[(5-benzyl-4-methyl-1,2,4-triazol-3-yl)sulfanyl]-N-(4-chlorophenyl)acetamide Chemical compound N=1N=C(SCC(=O)NC=2C=CC(Cl)=CC=2)N(C)C=1CC1=CC=CC=C1 WAJKAVZEYXRYGS-UHFFFAOYSA-N 0.000 claims 1
• SBBSBISWIJKQAZ-UHFFFAOYSA-N 2-[(5-benzyl-4-methyl-1,2,4-triazol-3-yl)sulfanyl]-N-(4-iodophenyl)acetamide Chemical compound N=1N=C(SCC(=O)NC=2C=CC(I)=CC=2)N(C)C=1CC1=CC=CC=C1 SBBSBISWIJKQAZ-UHFFFAOYSA-N 0.000 claims 1
• QZMSZPWFQDKEHJ-UHFFFAOYSA-N 2-[(5-benzylsulfanyl-4-methyl-1,2,4-triazol-3-yl)methyl]-4H-1,4-benzothiazin-3-one Chemical compound CN1C(CC2C(NC3=CC=CC=C3S2)=O)=NN=C1SCC1=CC=CC=C1 QZMSZPWFQDKEHJ-UHFFFAOYSA-N 0.000 claims 1
• ZYDQGTNFFKJZLA-UHFFFAOYSA-N 2-[(5-cyclohexyl-4-ethyl-1,2,4-triazol-3-yl)sulfanyl]-1-(4-methoxyphenyl)ethanone Chemical compound N=1N=C(C2CCCCC2)N(CC)C=1SCC(=O)C1=CC=C(OC)C=C1 ZYDQGTNFFKJZLA-UHFFFAOYSA-N 0.000 claims 1
• QANHFZMZEGPXSC-UHFFFAOYSA-N 2-[(5-cyclohexyl-4-ethyl-1,2,4-triazol-3-yl)sulfanyl]-1-phenylethanone Chemical compound N=1N=C(C2CCCCC2)N(CC)C=1SCC(=O)C1=CC=CC=C1 QANHFZMZEGPXSC-UHFFFAOYSA-N 0.000 claims 1
• RJFWWKKBHYIMDW-UHFFFAOYSA-N 2-[(5-cyclohexyl-4-ethyl-1,2,4-triazol-3-yl)sulfanyl]-N-(2-methyl-4-nitrophenyl)acetamide Chemical compound N=1N=C(C2CCCCC2)N(CC)C=1SCC(=O)NC1=CC=C([N+]([O-])=O)C=C1C RJFWWKKBHYIMDW-UHFFFAOYSA-N 0.000 claims 1
• WJSFRZIWYCRWDI-UHFFFAOYSA-N 2-[(5-cyclohexyl-4-ethyl-1,2,4-triazol-3-yl)sulfanyl]-N-(2-nitrophenyl)acetamide Chemical compound N=1N=C(C2CCCCC2)N(CC)C=1SCC(=O)NC1=CC=CC=C1[N+]([O-])=O WJSFRZIWYCRWDI-UHFFFAOYSA-N 0.000 claims 1
• WNVMRZOLJARALA-UHFFFAOYSA-N 2-[(5-cyclohexyl-4-ethyl-1,2,4-triazol-3-yl)sulfanyl]-N-(3-nitrophenyl)acetamide Chemical compound N=1N=C(C2CCCCC2)N(CC)C=1SCC(=O)NC1=CC=CC([N+]([O-])=O)=C1 WNVMRZOLJARALA-UHFFFAOYSA-N 0.000 claims 1
• IIKLXUMHNDYQQF-UHFFFAOYSA-N 2-[(5-cyclohexyl-4-ethyl-1,2,4-triazol-3-yl)sulfanyl]-N-(4-ethoxyphenyl)acetamide Chemical compound C1=CC(OCC)=CC=C1NC(=O)CSC(N1CC)=NN=C1C1CCCCC1 IIKLXUMHNDYQQF-UHFFFAOYSA-N 0.000 claims 1
• DXERDAKIOVTIFN-UHFFFAOYSA-N 2-[(5-cyclohexyl-4-ethyl-1,2,4-triazol-3-yl)sulfanyl]-N-(4-methyl-3-nitrophenyl)acetamide Chemical compound N=1N=C(C2CCCCC2)N(CC)C=1SCC(=O)NC1=CC=C(C)C([N+]([O-])=O)=C1 DXERDAKIOVTIFN-UHFFFAOYSA-N 0.000 claims 1
• FBIFPUDWSYBGMN-UHFFFAOYSA-N 2-[(5-cyclohexyl-4-ethyl-1,2,4-triazol-3-yl)sulfanyl]-N-(4-nitrophenyl)acetamide Chemical compound N=1N=C(C2CCCCC2)N(CC)C=1SCC(=O)NC1=CC=C([N+]([O-])=O)C=C1 FBIFPUDWSYBGMN-UHFFFAOYSA-N 0.000 claims 1
• COJGVVNCUDFCKV-UHFFFAOYSA-N 2-[(5-cyclohexyl-4-ethyl-1,2,4-triazol-3-yl)sulfanyl]-N-(4-nitrophenyl)propanamide Chemical compound N=1N=C(C2CCCCC2)N(CC)C=1SC(C)C(=O)NC1=CC=C([N+]([O-])=O)C=C1 COJGVVNCUDFCKV-UHFFFAOYSA-N 0.000 claims 1
• OXXLXHAZFARENP-UHFFFAOYSA-N 2-[(5-cyclohexyl-4-ethyl-1,2,4-triazol-3-yl)sulfanyl]-N-(5-ethyl-1,3,4-thiadiazol-2-yl)acetamide Chemical compound S1C(CC)=NN=C1NC(=O)CSC(N1CC)=NN=C1C1CCCCC1 OXXLXHAZFARENP-UHFFFAOYSA-N 0.000 claims 1
• DHCMBXNYCQDXLU-UHFFFAOYSA-N 2-[(5-cyclohexyl-4-ethyl-1,2,4-triazol-3-yl)sulfanyl]-N-[3-(trifluoromethyl)phenyl]acetamide Chemical compound N=1N=C(C2CCCCC2)N(CC)C=1SCC(=O)NC1=CC=CC(C(F)(F)F)=C1 DHCMBXNYCQDXLU-UHFFFAOYSA-N 0.000 claims 1
• DXLJWUKMMDUAAG-UHFFFAOYSA-N 2-[(5-cyclohexyl-4-ethyl-1,2,4-triazol-3-yl)sulfanyl]-N-naphthalen-1-ylacetamide Chemical compound CCN1C(SCC(=O)NC=2C3=CC=CC=C3C=CC=2)=NN=C1C1CCCCC1 DXLJWUKMMDUAAG-UHFFFAOYSA-N 0.000 claims 1
• KVCLNAAPESALBU-UHFFFAOYSA-N 2-[(5-cyclohexyl-4-ethyl-1,2,4-triazol-3-yl)sulfanyl]-N-phenylacetamide Chemical compound N=1N=C(C2CCCCC2)N(CC)C=1SCC(=O)NC1=CC=CC=C1 KVCLNAAPESALBU-UHFFFAOYSA-N 0.000 claims 1
• WUVDSBMAURLEAZ-UHFFFAOYSA-N 2-[(5-cyclohexyl-4-methyl-1,2,4-triazol-3-yl)sulfanyl]-1-(4-methoxyphenyl)ethanone Chemical compound C1=CC(OC)=CC=C1C(=O)CSC(N1C)=NN=C1C1CCCCC1 WUVDSBMAURLEAZ-UHFFFAOYSA-N 0.000 claims 1
• SJBSKRGOCIPQQT-UHFFFAOYSA-N 2-[(5-cyclohexyl-4-methyl-1,2,4-triazol-3-yl)sulfanyl]-1-phenylethanone Chemical compound N=1N=C(C2CCCCC2)N(C)C=1SCC(=O)C1=CC=CC=C1 SJBSKRGOCIPQQT-UHFFFAOYSA-N 0.000 claims 1
• QEJQODUVUVQJMH-UHFFFAOYSA-N 2-[(5-cyclohexyl-4-methyl-1,2,4-triazol-3-yl)sulfanyl]-N-(2-methyl-4-nitrophenyl)acetamide Chemical compound CC1=CC([N+]([O-])=O)=CC=C1NC(=O)CSC(N1C)=NN=C1C1CCCCC1 QEJQODUVUVQJMH-UHFFFAOYSA-N 0.000 claims 1
• ACOXSXYLINCOOJ-UHFFFAOYSA-N 2-[(5-cyclohexyl-4-methyl-1,2,4-triazol-3-yl)sulfanyl]-N-(3,4-dichlorophenyl)acetamide Chemical compound N=1N=C(C2CCCCC2)N(C)C=1SCC(=O)NC1=CC=C(Cl)C(Cl)=C1 ACOXSXYLINCOOJ-UHFFFAOYSA-N 0.000 claims 1
• LJJXGTQNGLBJEV-UHFFFAOYSA-N 2-[(5-cyclohexyl-4-methyl-1,2,4-triazol-3-yl)sulfanyl]-N-(3-nitrophenyl)acetamide Chemical compound N=1N=C(C2CCCCC2)N(C)C=1SCC(=O)NC1=CC=CC([N+]([O-])=O)=C1 LJJXGTQNGLBJEV-UHFFFAOYSA-N 0.000 claims 1
• XIZYLFNKTSKZNN-UHFFFAOYSA-N 2-[(5-cyclohexyl-4-methyl-1,2,4-triazol-3-yl)sulfanyl]-N-(4-iodo-2-methylphenyl)acetamide Chemical compound CC1=CC(I)=CC=C1NC(=O)CSC(N1C)=NN=C1C1CCCCC1 XIZYLFNKTSKZNN-UHFFFAOYSA-N 0.000 claims 1
• LBTKHNWMHQXHGB-UHFFFAOYSA-N 2-[(5-cyclohexyl-4-methyl-1,2,4-triazol-3-yl)sulfanyl]-N-(4-methoxyphenyl)acetamide Chemical compound C1=CC(OC)=CC=C1NC(=O)CSC(N1C)=NN=C1C1CCCCC1 LBTKHNWMHQXHGB-UHFFFAOYSA-N 0.000 claims 1
• DPPSKBNKVDYAKX-UHFFFAOYSA-N 2-[(5-cyclohexyl-4-methyl-1,2,4-triazol-3-yl)sulfanyl]-N-phenylacetamide Chemical compound N=1N=C(C2CCCCC2)N(C)C=1SCC(=O)NC1=CC=CC=C1 DPPSKBNKVDYAKX-UHFFFAOYSA-N 0.000 claims 1
• UULSGYZITMMALJ-UHFFFAOYSA-N 2-[(5-phenyl-1H-imidazol-2-yl)sulfanyl]-N-(2,4,4-trimethylpentan-2-yl)acetamide Chemical compound N1C(SCC(=O)NC(C)(C)CC(C)(C)C)=NC=C1C1=CC=CC=C1 UULSGYZITMMALJ-UHFFFAOYSA-N 0.000 claims 1
• OROJQMWAAMSHCB-UHFFFAOYSA-N 2-[(6-amino-1,3-benzothiazol-2-yl)sulfanyl]-N-cyclohexylacetamide Chemical compound S1C2=CC(N)=CC=C2N=C1SCC(=O)NC1CCCCC1 OROJQMWAAMSHCB-UHFFFAOYSA-N 0.000 claims 1
• KDLAKIOJEPTQDT-UHFFFAOYSA-N 2-[1-(2,5-dimethylphenyl)tetrazol-5-yl]sulfanyl-N-phenyl-N-propan-2-ylacetamide Chemical compound C=1C=CC=CC=1N(C(C)C)C(=O)CSC1=NN=NN1C1=CC(C)=CC=C1C KDLAKIOJEPTQDT-UHFFFAOYSA-N 0.000 claims 1
• FZAXAPQYHLECOI-UHFFFAOYSA-N 2-[1-(2,6-dimethylmorpholin-4-yl)-1-oxopropan-2-yl]isoindole-1,3-dione Chemical compound O=C1C2=CC=CC=C2C(=O)N1C(C)C(=O)N1CC(C)OC(C)C1 FZAXAPQYHLECOI-UHFFFAOYSA-N 0.000 claims 1
• SAIAGGQCMGMEIA-UHFFFAOYSA-N 2-[1-(4-chlorophenyl)sulfonylbenzimidazol-2-yl]sulfanyl-N-(thiophen-2-ylmethyl)acetamide Chemical compound C1=CC(Cl)=CC=C1S(=O)(=O)N1C2=CC=CC=C2N=C1SCC(=O)NCC1=CC=CS1 SAIAGGQCMGMEIA-UHFFFAOYSA-N 0.000 claims 1
• WHZXXYYHHHQBQY-UHFFFAOYSA-N 2-[1-(azepan-1-yl)-3-methyl-1-oxobutan-2-yl]isoindole-1,3-dione Chemical compound O=C1C2=CC=CC=C2C(=O)N1C(C(C)C)C(=O)N1CCCCCC1 WHZXXYYHHHQBQY-UHFFFAOYSA-N 0.000 claims 1
• TVUZQZKYWYADOX-UHFFFAOYSA-N 2-[1-morpholin-4-yl-3-(4-nitrophenyl)-1-oxopropan-2-yl]isoindole-1,3-dione Chemical compound C1=CC([N+](=O)[O-])=CC=C1CC(C(=O)N1CCOCC1)N1C(=O)C2=CC=CC=C2C1=O TVUZQZKYWYADOX-UHFFFAOYSA-N 0.000 claims 1
• XDUFXJIZTFOCLG-UHFFFAOYSA-N 2-[2-(4-chlorophenyl)-2-adamantyl]-1-(4-methylpiperazin-1-yl)ethanone Chemical compound C1CN(C)CCN1C(=O)CC1(C=2C=CC(Cl)=CC=2)C(C2)CC3CC2CC1C3 XDUFXJIZTFOCLG-UHFFFAOYSA-N 0.000 claims 1
• GGKNHRRHTQJTTL-UHFFFAOYSA-N 2-[2-(4-chlorophenyl)-2-adamantyl]-1-[4-(4-methoxyphenyl)piperazin-1-yl]ethanone Chemical compound C1=CC(OC)=CC=C1N1CCN(C(=O)CC2(C3CC4CC(C3)CC2C4)C=2C=CC(Cl)=CC=2)CC1 GGKNHRRHTQJTTL-UHFFFAOYSA-N 0.000 claims 1
• OGOUTJBZNBTLDZ-UHFFFAOYSA-N 2-[2-(4-chlorophenyl)-2-adamantyl]-N-(2-hydroxyethyl)acetamide Chemical compound C1C2CC(C3)CC1CC3C2(CC(=O)NCCO)C1=CC=C(Cl)C=C1 OGOUTJBZNBTLDZ-UHFFFAOYSA-N 0.000 claims 1
• BOKVJFHTLJCVEB-UHFFFAOYSA-N 2-[2-(5-bicyclo[2.2.1]hept-2-enylamino)-4-oxo-1,3-thiazol-5-yl]-N-(2-chlorophenyl)acetamide Chemical compound ClC1=CC=CC=C1NC(=O)CC1C(=O)N=C(NC2C3CC(C=C3)C2)S1 BOKVJFHTLJCVEB-UHFFFAOYSA-N 0.000 claims 1
• HPOGVCKERGTYKP-UHFFFAOYSA-N 2-[2-[[(2-amino-2-oxoethyl)-[3-methoxy-5-(pyridine-2-carbonyl)benzoyl]amino]methyl]phenoxy]acetic acid Chemical compound C=1C(OC)=CC(C(=O)N(CC(N)=O)CC=2C(=CC=CC=2)OCC(O)=O)=CC=1C(=O)C1=CC=CC=N1 HPOGVCKERGTYKP-UHFFFAOYSA-N 0.000 claims 1
• JYVBDKZKULSJKM-UHFFFAOYSA-N 2-[2-[[2-methoxyethyl-[3-methoxy-5-(pyridine-2-carbonyl)benzoyl]amino]methyl]phenoxy]acetic acid Chemical compound C=1C(OC)=CC(C(=O)C=2N=CC=CC=2)=CC=1C(=O)N(CCOC)CC1=CC=CC=C1OCC(O)=O JYVBDKZKULSJKM-UHFFFAOYSA-N 0.000 claims 1
• LLOIADUZZZXHIZ-UHFFFAOYSA-N 2-[2-[[[3-methoxy-5-(pyridine-2-carbonyl)benzoyl]-(3-methylbutyl)amino]methyl]phenoxy]acetic acid Chemical compound C=1C(OC)=CC(C(=O)N(CCC(C)C)CC=2C(=CC=CC=2)OCC(O)=O)=CC=1C(=O)C1=CC=CC=N1 LLOIADUZZZXHIZ-UHFFFAOYSA-N 0.000 claims 1
• IHPWLYWFNHBBJS-UHFFFAOYSA-N 2-[2-[[[3-methoxy-5-(pyridine-2-carbonyl)benzoyl]-methylamino]methyl]phenoxy]acetic acid Chemical compound C=1C(OC)=CC(C(=O)N(C)CC=2C(=CC=CC=2)OCC(O)=O)=CC=1C(=O)C1=CC=CC=N1 IHPWLYWFNHBBJS-UHFFFAOYSA-N 0.000 claims 1
• NQGOXWWAGHYVOM-UHFFFAOYSA-N 2-[2-[[[3-methoxy-5-(pyridine-2-carbonyl)benzoyl]-pyridin-4-ylamino]methyl]phenoxy]acetic acid Chemical compound C=1C(OC)=CC(C(=O)N(CC=2C(=CC=CC=2)OCC(O)=O)C=2C=CN=CC=2)=CC=1C(=O)C1=CC=CC=N1 NQGOXWWAGHYVOM-UHFFFAOYSA-N 0.000 claims 1
• BAYIZJYSJMYCJL-UHFFFAOYSA-N 2-[2-[[cyclopentyl-[3-methoxy-5-(pyridine-2-carbonyl)benzoyl]amino]methyl]phenoxy]acetic acid Chemical compound C=1C(OC)=CC(C(=O)N(CC=2C(=CC=CC=2)OCC(O)=O)C2CCCC2)=CC=1C(=O)C1=CC=CC=N1 BAYIZJYSJMYCJL-UHFFFAOYSA-N 0.000 claims 1
• SOQRFSOECBDGBK-UHFFFAOYSA-N 2-[2-[[cyclopropyl-[3-methoxy-5-(pyridine-2-carbonyl)benzoyl]amino]methyl]phenoxy]acetic acid Chemical compound C=1C(OC)=CC(C(=O)N(CC=2C(=CC=CC=2)OCC(O)=O)C2CC2)=CC=1C(=O)C1=CC=CC=N1 SOQRFSOECBDGBK-UHFFFAOYSA-N 0.000 claims 1
• UHBRHCQVLCYCRF-UHFFFAOYSA-N 2-[2-[[cyclopropylmethyl-[3-methoxy-5-(pyridine-2-carbonyl)benzoyl]amino]methyl]phenoxy]acetic acid Chemical compound C=1C(OC)=CC(C(=O)N(CC2CC2)CC=2C(=CC=CC=2)OCC(O)=O)=CC=1C(=O)C1=CC=CC=N1 UHBRHCQVLCYCRF-UHFFFAOYSA-N 0.000 claims 1
• QXOUJYYPDNMONW-UHFFFAOYSA-N 2-[3-(2-ethylpiperidin-1-yl)-3-oxopropyl]isoindole-1,3-dione Chemical compound CCC1CCCCN1C(=O)CCN1C(=O)C2=CC=CC=C2C1=O QXOUJYYPDNMONW-UHFFFAOYSA-N 0.000 claims 1
• MBRMOBDUCLMTMR-UHFFFAOYSA-N 2-[3-(azepane-1-carbonyl)phenyl]isoindole-1,3-dione Chemical compound C=1C=CC(N2C(C3=CC=CC=C3C2=O)=O)=CC=1C(=O)N1CCCCCC1 MBRMOBDUCLMTMR-UHFFFAOYSA-N 0.000 claims 1
• FZHRSQSHHALACN-UHFFFAOYSA-N 2-[3-[2-(2-chloroanilino)-2-oxoethyl]-1-adamantyl]-N-(2-chlorophenyl)acetamide Chemical compound ClC1=CC=CC=C1NC(=O)CC1(CC(CC(=O)NC=2C(=CC=CC=2)Cl)(C2)C3)CC3CC2C1 FZHRSQSHHALACN-UHFFFAOYSA-N 0.000 claims 1
• WSEFWDLSBIPVAF-UHFFFAOYSA-N 2-[3-[4-(2-chlorophenyl)piperazin-1-yl]-3-oxopropyl]isoindole-1,3-dione Chemical compound ClC1=CC=CC=C1N1CCN(C(=O)CCN2C(C3=CC=CC=C3C2=O)=O)CC1 WSEFWDLSBIPVAF-UHFFFAOYSA-N 0.000 claims 1
• GVQXUZISFDJWHR-UHFFFAOYSA-N 2-[3-imidazol-1-ylpropyl-[3-methoxy-5-(pyridine-2-carbonyl)benzoyl]amino]acetic acid Chemical compound C=1C(OC)=CC(C(=O)N(CCCN2C=NC=C2)CC(O)=O)=CC=1C(=O)C1=CC=CC=N1 GVQXUZISFDJWHR-UHFFFAOYSA-N 0.000 claims 1
• BMJFHITXZQCGRM-UHFFFAOYSA-N 2-[4-(1,3-benzothiazol-2-yl)piperazin-1-yl]-N-cyclohexylacetamide Chemical compound C1CN(C=2SC3=CC=CC=C3N=2)CCN1CC(=O)NC1CCCCC1 BMJFHITXZQCGRM-UHFFFAOYSA-N 0.000 claims 1
• ZHONOIXVBFLUNK-UHFFFAOYSA-N 2-[4-(2-methoxyethyl)-5-(2-methoxyethylsulfanyl)-1,2,4-triazol-3-yl]-1-methylpiperidine Chemical compound COCCN1C(SCCOC)=NN=C1C1N(C)CCCC1 ZHONOIXVBFLUNK-UHFFFAOYSA-N 0.000 claims 1
• BLNIYEIMTLMHGY-UHFFFAOYSA-N 2-[4-(2-methylpropyl)phenyl]-N-(1-phenylethyl)propanamide Chemical compound C1=CC(CC(C)C)=CC=C1C(C)C(=O)NC(C)C1=CC=CC=C1 BLNIYEIMTLMHGY-UHFFFAOYSA-N 0.000 claims 1
• JBDYWCYCAGIOLC-UHFFFAOYSA-N 2-[4-(3,3,4-trimethyl-7-azabicyclo[3.2.1]octane-7-carbonyl)phenyl]isoindole-1,3-dione Chemical compound O=C1C2=CC=CC=C2C(=O)N1C(C=C1)=CC=C1C(=O)N(C1)C2CC1C(C)C(C)(C)C2 JBDYWCYCAGIOLC-UHFFFAOYSA-N 0.000 claims 1
• YFQOUUOEKOIYSD-UHFFFAOYSA-N 2-[4-(adamantane-1-carbonylamino)phenoxy]acetic acid Chemical compound C1=CC(OCC(=O)O)=CC=C1NC(=O)C1(C2)CC(C3)CC2CC3C1 YFQOUUOEKOIYSD-UHFFFAOYSA-N 0.000 claims 1
• FNLCUAJTUGOSBS-UHFFFAOYSA-N 2-[4-(cyclopropylmethyl)-5-(2-methoxyethylsulfanyl)-1,2,4-triazol-3-yl]-1-methylpiperidine Chemical compound C1CC1CN1C(SCCOC)=NN=C1C1CCCCN1C FNLCUAJTUGOSBS-UHFFFAOYSA-N 0.000 claims 1
• JTLLXTGXSYXFGS-UHFFFAOYSA-N 2-[4-cyclopropyl-5-(2-methoxyethylsulfanyl)-1,2,4-triazol-3-yl]-1-methylpiperidine Chemical compound C1CC1N1C(SCCOC)=NN=C1C1CCCCN1C JTLLXTGXSYXFGS-UHFFFAOYSA-N 0.000 claims 1
• ZTIVMPXZJVAAJY-UHFFFAOYSA-N 2-[4-ethyl-5-[(2-nitrophenyl)methylsulfanyl]-1,2,4-triazol-3-yl]pyridine Chemical compound N=1N=C(C=2N=CC=CC=2)N(CC)C=1SCC1=CC=CC=C1[N+]([O-])=O ZTIVMPXZJVAAJY-UHFFFAOYSA-N 0.000 claims 1
• TUGNHRLVKXOBPA-UHFFFAOYSA-N 2-[4-ethyl-5-[(3-nitrophenyl)methylsulfanyl]-1,2,4-triazol-3-yl]pyridine Chemical compound N=1N=C(C=2N=CC=CC=2)N(CC)C=1SCC1=CC=CC([N+]([O-])=O)=C1 TUGNHRLVKXOBPA-UHFFFAOYSA-N 0.000 claims 1
• WJVLMPBAYGZROF-UHFFFAOYSA-N 2-[4-ethyl-5-[(4-methylphenyl)methylsulfanyl]-1,2,4-triazol-3-yl]pyridine Chemical compound N=1N=C(C=2N=CC=CC=2)N(CC)C=1SCC1=CC=C(C)C=C1 WJVLMPBAYGZROF-UHFFFAOYSA-N 0.000 claims 1
• NYYAQIMMHUNUBK-UHFFFAOYSA-N 2-[4-ethyl-5-[(4-methylsulfonylphenyl)methylsulfanyl]-1,2,4-triazol-3-yl]pyridine Chemical compound N=1N=C(C=2N=CC=CC=2)N(CC)C=1SCC1=CC=C(S(C)(=O)=O)C=C1 NYYAQIMMHUNUBK-UHFFFAOYSA-N 0.000 claims 1
• GTSUZRJCUKMHSE-UHFFFAOYSA-N 2-[4-ethyl-5-[(4-nitrophenyl)methylsulfanyl]-1,2,4-triazol-3-yl]pyridine Chemical compound N=1N=C(C=2N=CC=CC=2)N(CC)C=1SCC1=CC=C([N+]([O-])=O)C=C1 GTSUZRJCUKMHSE-UHFFFAOYSA-N 0.000 claims 1
• KMTWAGYEIDEIFJ-UHFFFAOYSA-N 2-[4-ethyl-5-[(4-phenylmethoxyphenyl)methylsulfanyl]-1,2,4-triazol-3-yl]pyridine Chemical compound N=1N=C(C=2N=CC=CC=2)N(CC)C=1SCC(C=C1)=CC=C1OCC1=CC=CC=C1 KMTWAGYEIDEIFJ-UHFFFAOYSA-N 0.000 claims 1
• MNMAXWCOHZMSRC-UHFFFAOYSA-N 2-[4-ethyl-5-[(5-methyl-2-nitrophenyl)methylsulfanyl]-1,2,4-triazol-3-yl]pyridine Chemical compound N=1N=C(C=2N=CC=CC=2)N(CC)C=1SCC1=CC(C)=CC=C1[N+]([O-])=O MNMAXWCOHZMSRC-UHFFFAOYSA-N 0.000 claims 1
• QUKLUPQXVGHINW-UHFFFAOYSA-N 2-[4-ethyl-5-[[3-(trifluoromethoxy)phenyl]methylsulfanyl]-1,2,4-triazol-3-yl]pyridine Chemical compound N=1N=C(C=2N=CC=CC=2)N(CC)C=1SCC1=CC=CC(OC(F)(F)F)=C1 QUKLUPQXVGHINW-UHFFFAOYSA-N 0.000 claims 1
• QDXABEWTQGXEKY-UHFFFAOYSA-N 2-[4-ethyl-5-[[4-(trifluoromethyl)phenyl]methylsulfanyl]-1,2,4-triazol-3-yl]pyridine Chemical compound N=1N=C(C=2N=CC=CC=2)N(CC)C=1SCC1=CC=C(C(F)(F)F)C=C1 QDXABEWTQGXEKY-UHFFFAOYSA-N 0.000 claims 1
• ZGNBIWKKFDMVPK-UHFFFAOYSA-N 2-[5-(2-methoxyethylsulfanyl)-4-(3-methoxypropyl)-1,2,4-triazol-3-yl]-1-methylpiperidine Chemical compound COCCCN1C(SCCOC)=NN=C1C1N(C)CCCC1 ZGNBIWKKFDMVPK-UHFFFAOYSA-N 0.000 claims 1
• ODDJKPUTMQGORL-UHFFFAOYSA-N 2-[5-(3,3,5-trimethyl-7-azabicyclo[3.2.1]octane-7-carbonyl)indol-1-yl]acetamide Chemical compound C1=C2N(CC(N)=O)C=CC2=CC(C(=O)N2C3CC(CC(C)(C)C3)(C2)C)=C1 ODDJKPUTMQGORL-UHFFFAOYSA-N 0.000 claims 1
• IIKUPAABISOFBR-UHFFFAOYSA-N 2-[5-[(3,5-dimethoxyphenyl)methylsulfanyl]-4-ethyl-1,2,4-triazol-3-yl]pyridine Chemical compound N=1N=C(C=2N=CC=CC=2)N(CC)C=1SCC1=CC(OC)=CC(OC)=C1 IIKUPAABISOFBR-UHFFFAOYSA-N 0.000 claims 1
• OTVOFYWDCZQTGH-UHFFFAOYSA-N 2-[5-[(4-bromophenyl)methylsulfanyl]-4-ethyl-1,2,4-triazol-3-yl]pyridine Chemical compound N=1N=C(C=2N=CC=CC=2)N(CC)C=1SCC1=CC=C(Br)C=C1 OTVOFYWDCZQTGH-UHFFFAOYSA-N 0.000 claims 1
• SATPLZDPPWUWBL-UHFFFAOYSA-N 2-[5-[(6-chloro-1,3-benzodioxol-5-yl)methylsulfanyl]-4-ethyl-1,2,4-triazol-3-yl]pyridine;2-[5-[(3,4-dichlorophenyl)methylsulfanyl]-4-ethyl-1,2,4-triazol-3-yl]pyridine Chemical compound N=1N=C(C=2N=CC=CC=2)N(CC)C=1SCC1=CC=C(Cl)C(Cl)=C1.CCN1C(SCC=2C(=CC=3OCOC=3C=2)Cl)=NN=C1C1=CC=CC=N1 SATPLZDPPWUWBL-UHFFFAOYSA-N 0.000 claims 1
• RIGVLRAAKUKKCB-BMRADRMJSA-N 2-[[(5Z)-5-(6-oxocyclohexa-2,4-dien-1-ylidene)-4-(2-phenylethyl)-1H-1,2,4-triazol-3-yl]sulfanyl]acetonitrile Chemical compound O=C1C=CC=C\C1=C\1N(CCC=2C=CC=CC=2)C(SCC#N)=NN/1 RIGVLRAAKUKKCB-BMRADRMJSA-N 0.000 claims 1
• MQMLZZKIPVOGLT-UHFFFAOYSA-N 2-[[2-(2-phenyl-2-adamantyl)acetyl]amino]ethyl thiophene-2-carboxylate Chemical compound C=1C=CSC=1C(=O)OCCNC(=O)CC1(C2CC3CC(C2)CC1C3)C1=CC=CC=C1 MQMLZZKIPVOGLT-UHFFFAOYSA-N 0.000 claims 1
• HDFLDTVIHCSPFN-UHFFFAOYSA-N 2-[[3-methoxy-5-(pyridine-2-carbonyl)benzoyl]-(2-oxoazepan-3-yl)amino]acetic acid Chemical compound C=1C(OC)=CC(C(=O)N(CC(O)=O)C2C(NCCCC2)=O)=CC=1C(=O)C1=CC=CC=N1 HDFLDTVIHCSPFN-UHFFFAOYSA-N 0.000 claims 1
• KBEPEFQMIXNIJJ-UHFFFAOYSA-N 2-[[3-methoxy-5-(pyridine-2-carbonyl)benzoyl]-pyridin-4-ylamino]acetic acid Chemical compound C=1C(OC)=CC(C(=O)N(CC(O)=O)C=2C=CN=CC=2)=CC=1C(=O)C1=CC=CC=N1 KBEPEFQMIXNIJJ-UHFFFAOYSA-N 0.000 claims 1
• BUZUEAQKXXRHHX-UHFFFAOYSA-N 2-[[4-(2-methoxyethyl)-5-(1-methylpiperidin-2-yl)-1,2,4-triazol-3-yl]sulfanylmethyl]benzonitrile Chemical compound N=1N=C(C2N(CCCC2)C)N(CCOC)C=1SCC1=CC=CC=C1C#N BUZUEAQKXXRHHX-UHFFFAOYSA-N 0.000 claims 1
• VRJCGUHXIVYUJK-UHFFFAOYSA-N 2-[[4-(2-methoxyethyl)-5-(1-methylpiperidin-2-yl)-1,2,4-triazol-3-yl]sulfanylmethyl]pyridine Chemical compound N=1N=C(C2N(CCCC2)C)N(CCOC)C=1SCC1=CC=CC=N1 VRJCGUHXIVYUJK-UHFFFAOYSA-N 0.000 claims 1
• CDDRZDBYXZDANF-UHFFFAOYSA-N 2-[[4-(2-methoxyethyl)-5-(2-methoxyphenyl)-1,2,4-triazol-3-yl]sulfanylmethyl]benzonitrile Chemical compound N=1N=C(C=2C(=CC=CC=2)OC)N(CCOC)C=1SCC1=CC=CC=C1C#N CDDRZDBYXZDANF-UHFFFAOYSA-N 0.000 claims 1
• AAIBAWKSPDZOQE-UHFFFAOYSA-N 2-[[4-(2-methoxyethyl)-5-(2-methoxyphenyl)-1,2,4-triazol-3-yl]sulfanylmethyl]pyridine Chemical compound N=1N=C(C=2C(=CC=CC=2)OC)N(CCOC)C=1SCC1=CC=CC=N1 AAIBAWKSPDZOQE-UHFFFAOYSA-N 0.000 claims 1
• JHKXWKOBFAQZJH-UHFFFAOYSA-N 2-[[4-(2-methoxyethyl)-5-thiophen-2-yl-1,2,4-triazol-3-yl]sulfanylmethyl]benzonitrile Chemical compound N=1N=C(C=2SC=CC=2)N(CCOC)C=1SCC1=CC=CC=C1C#N JHKXWKOBFAQZJH-UHFFFAOYSA-N 0.000 claims 1
• BQOYHCFNYWYRSL-UHFFFAOYSA-N 2-[[4-(2-methoxyethyl)-5-thiophen-2-yl-1,2,4-triazol-3-yl]sulfanylmethyl]pyridine Chemical compound N=1N=C(C=2SC=CC=2)N(CCOC)C=1SCC1=CC=CC=N1 BQOYHCFNYWYRSL-UHFFFAOYSA-N 0.000 claims 1
• IMABNNILBXTTEB-UHFFFAOYSA-N 2-[[4-(2-phenylethyl)-5-pyridin-4-yl-1,2,4-triazol-3-yl]sulfanyl]-1-pyridin-3-ylethanone Chemical compound C=1C=CN=CC=1C(=O)CSC(N1CCC=2C=CC=CC=2)=NN=C1C1=CC=NC=C1 IMABNNILBXTTEB-UHFFFAOYSA-N 0.000 claims 1
• UYJHAXNBUOMUFT-UHFFFAOYSA-N 2-[[4-(2-phenylethyl)-5-pyridin-4-yl-1,2,4-triazol-3-yl]sulfanyl]-N-(1,3-thiazol-2-yl)acetamide Chemical compound N=1C=CSC=1NC(=O)CSC(N1CCC=2C=CC=CC=2)=NN=C1C1=CC=NC=C1 UYJHAXNBUOMUFT-UHFFFAOYSA-N 0.000 claims 1
• ZHBZQXVDOAMMBX-UHFFFAOYSA-N 2-[[4-(2-phenylethyl)-5-pyridin-4-yl-1,2,4-triazol-3-yl]sulfanyl]-N-[3-(trifluoromethyl)phenyl]acetamide Chemical compound FC(F)(F)C1=CC=CC(NC(=O)CSC=2N(C(C=3C=CN=CC=3)=NN=2)CCC=2C=CC=CC=2)=C1 ZHBZQXVDOAMMBX-UHFFFAOYSA-N 0.000 claims 1
• IYCQTMVLDMLCJC-UHFFFAOYSA-N 2-[[4-(2-piperidin-1-ylethyl)-5-thiophen-2-yl-1,2,4-triazol-3-yl]sulfanylmethyl]benzonitrile Chemical compound N#CC1=CC=CC=C1CSC(N1CCN2CCCCC2)=NN=C1C1=CC=CS1 IYCQTMVLDMLCJC-UHFFFAOYSA-N 0.000 claims 1
• SEOIDFIIPDNWLM-UHFFFAOYSA-N 2-[[4-(2-piperidin-1-ylethyl)-5-thiophen-2-yl-1,2,4-triazol-3-yl]sulfanylmethyl]pyridine Chemical compound C1CCCCN1CCN(C(=NN=1)C=2SC=CC=2)C=1SCC1=CC=CC=N1 SEOIDFIIPDNWLM-UHFFFAOYSA-N 0.000 claims 1
• BHBVWXZUGWVDSZ-UHFFFAOYSA-N 2-[[4-(3-methoxypropyl)-5-(1-methylpiperidin-2-yl)-1,2,4-triazol-3-yl]sulfanylmethyl]benzonitrile Chemical compound N=1N=C(C2N(CCCC2)C)N(CCCOC)C=1SCC1=CC=CC=C1C#N BHBVWXZUGWVDSZ-UHFFFAOYSA-N 0.000 claims 1
• FRYXCPMUQMCSLY-UHFFFAOYSA-N 2-[[4-(3-methoxypropyl)-5-(1-methylpiperidin-2-yl)-1,2,4-triazol-3-yl]sulfanylmethyl]pyridine Chemical compound N=1N=C(C2N(CCCC2)C)N(CCCOC)C=1SCC1=CC=CC=N1 FRYXCPMUQMCSLY-UHFFFAOYSA-N 0.000 claims 1
• ARDDRMJDJCSFCJ-UHFFFAOYSA-N 2-[[4-(3-methoxypropyl)-5-thiophen-2-yl-1,2,4-triazol-3-yl]sulfanylmethyl]benzonitrile Chemical compound N=1N=C(C=2SC=CC=2)N(CCCOC)C=1SCC1=CC=CC=C1C#N ARDDRMJDJCSFCJ-UHFFFAOYSA-N 0.000 claims 1
• ZOWIZVSYPKGAES-UHFFFAOYSA-N 2-[[4-(3-methoxypropyl)-5-thiophen-2-yl-1,2,4-triazol-3-yl]sulfanylmethyl]pyridine Chemical compound N=1N=C(C=2SC=CC=2)N(CCCOC)C=1SCC1=CC=CC=N1 ZOWIZVSYPKGAES-UHFFFAOYSA-N 0.000 claims 1
• CLRVYXYMZPMEBK-UHFFFAOYSA-N 2-[[4-(cyclopropylmethyl)-5-(1-methylpiperidin-2-yl)-1,2,4-triazol-3-yl]sulfanylmethyl]benzonitrile Chemical compound CN1CCCCC1C(N1CC2CC2)=NN=C1SCC1=CC=CC=C1C#N CLRVYXYMZPMEBK-UHFFFAOYSA-N 0.000 claims 1
• YRINOYIGKLXCIQ-UHFFFAOYSA-N 2-[[4-(cyclopropylmethyl)-5-(1-methylpiperidin-2-yl)-1,2,4-triazol-3-yl]sulfanylmethyl]pyridine Chemical compound CN1CCCCC1C(N1CC2CC2)=NN=C1SCC1=CC=CC=N1 YRINOYIGKLXCIQ-UHFFFAOYSA-N 0.000 claims 1
• CBRGHNAWNYBXGL-UHFFFAOYSA-N 2-[[4-(cyclopropylmethyl)-5-(2-methoxyphenyl)-1,2,4-triazol-3-yl]sulfanylmethyl]benzonitrile Chemical compound COC1=CC=CC=C1C(N1CC2CC2)=NN=C1SCC1=CC=CC=C1C#N CBRGHNAWNYBXGL-UHFFFAOYSA-N 0.000 claims 1
• IGCVQHXVMZYPPW-UHFFFAOYSA-N 2-[[4-(cyclopropylmethyl)-5-(2-methoxyphenyl)-1,2,4-triazol-3-yl]sulfanylmethyl]pyridine Chemical compound COC1=CC=CC=C1C(N1CC2CC2)=NN=C1SCC1=CC=CC=N1 IGCVQHXVMZYPPW-UHFFFAOYSA-N 0.000 claims 1
• MVVFAXDEAJJUHX-UHFFFAOYSA-N 2-[[4-(cyclopropylmethyl)-5-thiophen-2-yl-1,2,4-triazol-3-yl]sulfanylmethyl]benzonitrile Chemical compound N#CC1=CC=CC=C1CSC(N1CC2CC2)=NN=C1C1=CC=CS1 MVVFAXDEAJJUHX-UHFFFAOYSA-N 0.000 claims 1
• XUZQLPIUBVOSPF-UHFFFAOYSA-N 2-[[4-(cyclopropylmethyl)-5-thiophen-2-yl-1,2,4-triazol-3-yl]sulfanylmethyl]pyridine Chemical compound C=1C=CC=NC=1CSC(N1CC2CC2)=NN=C1C1=CC=CS1 XUZQLPIUBVOSPF-UHFFFAOYSA-N 0.000 claims 1
• CULJGGGZAVWCJQ-UHFFFAOYSA-N 2-[[4-(furan-2-ylmethyl)-5-(2-methoxyphenyl)-1,2,4-triazol-3-yl]sulfanyl]-N-(2-methyl-4-nitrophenyl)acetamide Chemical compound COC1=CC=CC=C1C(N1CC=2OC=CC=2)=NN=C1SCC(=O)NC1=CC=C([N+]([O-])=O)C=C1C CULJGGGZAVWCJQ-UHFFFAOYSA-N 0.000 claims 1
• SNPVLGUNUSTUJR-UHFFFAOYSA-N 2-[[4-(furan-2-ylmethyl)-5-pyridin-4-yl-1,2,4-triazol-3-yl]sulfanyl]-1-(3-nitrophenyl)ethanone Chemical compound [O-][N+](=O)C1=CC=CC(C(=O)CSC=2N(C(C=3C=CN=CC=3)=NN=2)CC=2OC=CC=2)=C1 SNPVLGUNUSTUJR-UHFFFAOYSA-N 0.000 claims 1
• PFSOJXWTRNCUEB-UHFFFAOYSA-N 2-[[4-cyclopropyl-5-(1-methylpiperidin-2-yl)-1,2,4-triazol-3-yl]sulfanylmethyl]benzonitrile Chemical compound CN1CCCCC1C(N1C2CC2)=NN=C1SCC1=CC=CC=C1C#N PFSOJXWTRNCUEB-UHFFFAOYSA-N 0.000 claims 1
• FMVGOYIDPMFOFC-UHFFFAOYSA-N 2-[[4-cyclopropyl-5-(1-methylpiperidin-2-yl)-1,2,4-triazol-3-yl]sulfanylmethyl]pyridine Chemical compound CN1CCCCC1C(N1C2CC2)=NN=C1SCC1=CC=CC=N1 FMVGOYIDPMFOFC-UHFFFAOYSA-N 0.000 claims 1
• LINFGWOFLALQRP-UHFFFAOYSA-N 2-[[4-cyclopropyl-5-(2-methoxyphenyl)-1,2,4-triazol-3-yl]sulfanylmethyl]benzonitrile Chemical compound COC1=CC=CC=C1C(N1C2CC2)=NN=C1SCC1=CC=CC=C1C#N LINFGWOFLALQRP-UHFFFAOYSA-N 0.000 claims 1
• CTDSFRRXCMMZOY-UHFFFAOYSA-N 2-[[4-cyclopropyl-5-(2-methoxyphenyl)-1,2,4-triazol-3-yl]sulfanylmethyl]pyridine Chemical compound COC1=CC=CC=C1C(N1C2CC2)=NN=C1SCC1=CC=CC=N1 CTDSFRRXCMMZOY-UHFFFAOYSA-N 0.000 claims 1
• VZTCHSNKIJYKPH-UHFFFAOYSA-N 2-[[4-ethyl-5-(2-methoxyphenyl)-1,2,4-triazol-3-yl]sulfanyl]-1-(4-methoxyphenyl)ethanone Chemical compound N=1N=C(C=2C(=CC=CC=2)OC)N(CC)C=1SCC(=O)C1=CC=C(OC)C=C1 VZTCHSNKIJYKPH-UHFFFAOYSA-N 0.000 claims 1
• HMVPXJQFPDMWAX-UHFFFAOYSA-N 2-[[4-ethyl-5-(2-methoxyphenyl)-1,2,4-triazol-3-yl]sulfanyl]-N-(2-ethylphenyl)acetamide Chemical compound CCC1=CC=CC=C1NC(=O)CSC(N1CC)=NN=C1C1=CC=CC=C1OC HMVPXJQFPDMWAX-UHFFFAOYSA-N 0.000 claims 1
• NXOBQDGGXWNEJX-UHFFFAOYSA-N 2-[[4-ethyl-5-(2-methoxyphenyl)-1,2,4-triazol-3-yl]sulfanyl]-N-(4-methoxyphenyl)acetamide Chemical compound N=1N=C(C=2C(=CC=CC=2)OC)N(CC)C=1SCC(=O)NC1=CC=C(OC)C=C1 NXOBQDGGXWNEJX-UHFFFAOYSA-N 0.000 claims 1
• AYEMNPXYQMUAFQ-UHFFFAOYSA-N 2-[[4-ethyl-5-(2-methoxyphenyl)-1,2,4-triazol-3-yl]sulfanyl]-N-(4-methyl-3-nitrophenyl)acetamide Chemical compound N=1N=C(C=2C(=CC=CC=2)OC)N(CC)C=1SCC(=O)NC1=CC=C(C)C([N+]([O-])=O)=C1 AYEMNPXYQMUAFQ-UHFFFAOYSA-N 0.000 claims 1
• JJIGHLSEXQBPSV-UHFFFAOYSA-N 2-[[4-ethyl-5-(2-methoxyphenyl)-1,2,4-triazol-3-yl]sulfanyl]-N-(4-phenyl-1,3-thiazol-2-yl)acetamide Chemical compound N=1N=C(C=2C(=CC=CC=2)OC)N(CC)C=1SCC(=O)NC(SC=1)=NC=1C1=CC=CC=C1 JJIGHLSEXQBPSV-UHFFFAOYSA-N 0.000 claims 1
• KIFDCBRPKGGOJK-UHFFFAOYSA-N 2-[[4-ethyl-5-(2-methoxyphenyl)-1,2,4-triazol-3-yl]sulfanyl]-N-[3-(trifluoromethyl)phenyl]acetamide Chemical compound N=1N=C(C=2C(=CC=CC=2)OC)N(CC)C=1SCC(=O)NC1=CC=CC(C(F)(F)F)=C1 KIFDCBRPKGGOJK-UHFFFAOYSA-N 0.000 claims 1
• UMRKHJPJJDFGCY-UHFFFAOYSA-N 2-[[4-ethyl-5-(2-methoxyphenyl)-1,2,4-triazol-3-yl]sulfanyl]-N-naphthalen-1-ylpropanamide Chemical compound CCN1C(SC(C)C(=O)NC=2C3=CC=CC=C3C=CC=2)=NN=C1C1=CC=CC=C1OC UMRKHJPJJDFGCY-UHFFFAOYSA-N 0.000 claims 1
• IBTCHHIFBKNKJA-UHFFFAOYSA-N 2-[[4-ethyl-5-(2-methoxyphenyl)-1,2,4-triazol-3-yl]sulfanyl]-N-phenylpropanamide Chemical compound N=1N=C(C=2C(=CC=CC=2)OC)N(CC)C=1SC(C)C(=O)NC1=CC=CC=C1 IBTCHHIFBKNKJA-UHFFFAOYSA-N 0.000 claims 1
• BIXRBEZLDNXWOT-UHFFFAOYSA-N 2-[[4-ethyl-5-(3-methylphenyl)-1,2,4-triazol-3-yl]sulfanyl]-N-(2-nitrophenyl)acetamide Chemical compound N=1N=C(C=2C=C(C)C=CC=2)N(CC)C=1SCC(=O)NC1=CC=CC=C1[N+]([O-])=O BIXRBEZLDNXWOT-UHFFFAOYSA-N 0.000 claims 1
• UCNCULCBBKCGMT-UHFFFAOYSA-N 2-[[4-ethyl-5-(3-methylphenyl)-1,2,4-triazol-3-yl]sulfanyl]-N-(4-methyl-3-nitrophenyl)acetamide Chemical compound N=1N=C(C=2C=C(C)C=CC=2)N(CC)C=1SCC(=O)NC1=CC=C(C)C([N+]([O-])=O)=C1 UCNCULCBBKCGMT-UHFFFAOYSA-N 0.000 claims 1
• YISAVIXLONXTQF-UHFFFAOYSA-N 2-[[4-ethyl-5-(3-methylphenyl)-1,2,4-triazol-3-yl]sulfanyl]-N-(4-nitrophenyl)acetamide Chemical compound N=1N=C(C=2C=C(C)C=CC=2)N(CC)C=1SCC(=O)NC1=CC=C([N+]([O-])=O)C=C1 YISAVIXLONXTQF-UHFFFAOYSA-N 0.000 claims 1
• AJJSJOIPTPXSKS-UHFFFAOYSA-N 2-[[4-ethyl-5-(4-methoxyphenyl)-1,2,4-triazol-3-yl]sulfanyl]-1-(4-methoxyphenyl)ethanone Chemical compound N=1N=C(C=2C=CC(OC)=CC=2)N(CC)C=1SCC(=O)C1=CC=C(OC)C=C1 AJJSJOIPTPXSKS-UHFFFAOYSA-N 0.000 claims 1
• AHFDVHVFKYXPAQ-UHFFFAOYSA-N 2-[[4-ethyl-5-(4-methoxyphenyl)-1,2,4-triazol-3-yl]sulfanyl]-1-phenylethanone Chemical compound N=1N=C(C=2C=CC(OC)=CC=2)N(CC)C=1SCC(=O)C1=CC=CC=C1 AHFDVHVFKYXPAQ-UHFFFAOYSA-N 0.000 claims 1
• XZMCFSBRDJVADM-UHFFFAOYSA-N 2-[[4-ethyl-5-(4-methoxyphenyl)-1,2,4-triazol-3-yl]sulfanyl]-N-(4-methyl-3-nitrophenyl)acetamide Chemical compound N=1N=C(C=2C=CC(OC)=CC=2)N(CC)C=1SCC(=O)NC1=CC=C(C)C([N+]([O-])=O)=C1 XZMCFSBRDJVADM-UHFFFAOYSA-N 0.000 claims 1
• LVJKBTGFSKQXEC-UHFFFAOYSA-N 2-[[4-ethyl-5-(4-morpholin-4-ylsulfonylphenyl)-1,2,4-triazol-3-yl]sulfanyl]-1-(4-methylphenyl)ethanone Chemical compound N=1N=C(C=2C=CC(=CC=2)S(=O)(=O)N2CCOCC2)N(CC)C=1SCC(=O)C1=CC=C(C)C=C1 LVJKBTGFSKQXEC-UHFFFAOYSA-N 0.000 claims 1
• JYQRIXGZWNUCEU-UHFFFAOYSA-N 2-[[4-ethyl-5-(4-nitrophenyl)-1,2,4-triazol-3-yl]sulfanyl]-1-(4-methylphenyl)ethanone Chemical compound N=1N=C(C=2C=CC(=CC=2)[N+]([O-])=O)N(CC)C=1SCC(=O)C1=CC=C(C)C=C1 JYQRIXGZWNUCEU-UHFFFAOYSA-N 0.000 claims 1
• ZCDCZLGTVJACCG-UHFFFAOYSA-N 2-[[4-ethyl-5-(4-nitrophenyl)-1,2,4-triazol-3-yl]sulfanyl]-1-phenylethanone Chemical compound N=1N=C(C=2C=CC(=CC=2)[N+]([O-])=O)N(CC)C=1SCC(=O)C1=CC=CC=C1 ZCDCZLGTVJACCG-UHFFFAOYSA-N 0.000 claims 1
• LBISGMQVGFAQIA-UHFFFAOYSA-N 2-[[4-ethyl-5-(4-piperidin-1-ylsulfonylphenyl)-1,2,4-triazol-3-yl]sulfanyl]-1-(4-methylphenyl)ethanone Chemical compound N=1N=C(C=2C=CC(=CC=2)S(=O)(=O)N2CCCCC2)N(CC)C=1SCC(=O)C1=CC=C(C)C=C1 LBISGMQVGFAQIA-UHFFFAOYSA-N 0.000 claims 1
• UCXFFQAVKRUEMF-UHFFFAOYSA-N 2-[[4-ethyl-5-(4-piperidin-1-ylsulfonylphenyl)-1,2,4-triazol-3-yl]sulfanyl]-1-phenylethanone Chemical compound N=1N=C(C=2C=CC(=CC=2)S(=O)(=O)N2CCCCC2)N(CC)C=1SCC(=O)C1=CC=CC=C1 UCXFFQAVKRUEMF-UHFFFAOYSA-N 0.000 claims 1
• DPEYTPARTGASAS-UHFFFAOYSA-N 2-[[4-ethyl-5-(furan-2-yl)-1,2,4-triazol-3-yl]sulfanyl]-1-(4-methoxyphenyl)ethanone Chemical compound N=1N=C(C=2OC=CC=2)N(CC)C=1SCC(=O)C1=CC=C(OC)C=C1 DPEYTPARTGASAS-UHFFFAOYSA-N 0.000 claims 1
• BOTYZJBEPAFRIX-UHFFFAOYSA-N 2-[[4-ethyl-5-(furan-2-yl)-1,2,4-triazol-3-yl]sulfanyl]-1-(4-methylsulfonylphenyl)ethanone Chemical compound N=1N=C(C=2OC=CC=2)N(CC)C=1SCC(=O)C1=CC=C(S(C)(=O)=O)C=C1 BOTYZJBEPAFRIX-UHFFFAOYSA-N 0.000 claims 1
• LKXBQKNOOWEDNS-UHFFFAOYSA-N 2-[[4-ethyl-5-(furan-2-yl)-1,2,4-triazol-3-yl]sulfanyl]-1-phenylethanone Chemical compound N=1N=C(C=2OC=CC=2)N(CC)C=1SCC(=O)C1=CC=CC=C1 LKXBQKNOOWEDNS-UHFFFAOYSA-N 0.000 claims 1
• SAIJZRFYDGDCSD-UHFFFAOYSA-N 2-[[4-ethyl-5-(furan-2-yl)-1,2,4-triazol-3-yl]sulfanyl]-1-pyridin-3-ylethanone Chemical compound N=1N=C(C=2OC=CC=2)N(CC)C=1SCC(=O)C1=CC=CN=C1 SAIJZRFYDGDCSD-UHFFFAOYSA-N 0.000 claims 1
• LYUNDGAQTWGJPJ-UHFFFAOYSA-N 2-[[4-ethyl-5-[(4-fluoroanilino)methyl]-1,2,4-triazol-3-yl]sulfanyl]-1-(4-methoxyphenyl)ethanone Chemical compound N=1N=C(SCC(=O)C=2C=CC(OC)=CC=2)N(CC)C=1CNC1=CC=C(F)C=C1 LYUNDGAQTWGJPJ-UHFFFAOYSA-N 0.000 claims 1
• OQFFSYICUZUMCL-UHFFFAOYSA-N 2-[[4-ethyl-5-[(4-fluoroanilino)methyl]-1,2,4-triazol-3-yl]sulfanyl]-1-(4-methylphenyl)ethanone Chemical compound N=1N=C(SCC(=O)C=2C=CC(C)=CC=2)N(CC)C=1CNC1=CC=C(F)C=C1 OQFFSYICUZUMCL-UHFFFAOYSA-N 0.000 claims 1
• XNOHOYOJKRADKS-UHFFFAOYSA-N 2-[[4-ethyl-5-[(4-fluoroanilino)methyl]-1,2,4-triazol-3-yl]sulfanyl]-N-(2-nitrophenyl)acetamide Chemical compound N=1N=C(SCC(=O)NC=2C(=CC=CC=2)[N+]([O-])=O)N(CC)C=1CNC1=CC=C(F)C=C1 XNOHOYOJKRADKS-UHFFFAOYSA-N 0.000 claims 1
• CCFSLFQZFBBCII-UHFFFAOYSA-N 2-[[4-ethyl-5-[(4-fluoroanilino)methyl]-1,2,4-triazol-3-yl]sulfanyl]-N-(4-methyl-3-nitrophenyl)acetamide Chemical compound N=1N=C(SCC(=O)NC=2C=C(C(C)=CC=2)[N+]([O-])=O)N(CC)C=1CNC1=CC=C(F)C=C1 CCFSLFQZFBBCII-UHFFFAOYSA-N 0.000 claims 1
• YAETXVAHBRVUIL-UHFFFAOYSA-N 2-[[4-ethyl-5-[(4-fluoroanilino)methyl]-1,2,4-triazol-3-yl]sulfanyl]-N-(4-nitrophenyl)acetamide Chemical compound N=1N=C(SCC(=O)NC=2C=CC(=CC=2)[N+]([O-])=O)N(CC)C=1CNC1=CC=C(F)C=C1 YAETXVAHBRVUIL-UHFFFAOYSA-N 0.000 claims 1
• QZNKZVWHTCFSKQ-UHFFFAOYSA-N 2-[[4-ethyl-5-[(4-methoxyphenoxy)methyl]-1,2,4-triazol-3-yl]sulfanyl]-1-phenylethanone Chemical compound N=1N=C(SCC(=O)C=2C=CC=CC=2)N(CC)C=1COC1=CC=C(OC)C=C1 QZNKZVWHTCFSKQ-UHFFFAOYSA-N 0.000 claims 1
• NHUJAPJTCQCLIT-UHFFFAOYSA-N 2-[[4-ethyl-5-[(4-methylanilino)methyl]-1,2,4-triazol-3-yl]sulfanyl]-1-(4-methylphenyl)ethanone Chemical compound N=1N=C(SCC(=O)C=2C=CC(C)=CC=2)N(CC)C=1CNC1=CC=C(C)C=C1 NHUJAPJTCQCLIT-UHFFFAOYSA-N 0.000 claims 1
• QBDRVKMIADPSEQ-UHFFFAOYSA-N 2-[[4-methyl-5-(2-methylphenyl)-1,2,4-triazol-3-yl]sulfanyl]-1-(4-methylphenyl)ethanone Chemical compound C1=CC(C)=CC=C1C(=O)CSC(N1C)=NN=C1C1=CC=CC=C1C QBDRVKMIADPSEQ-UHFFFAOYSA-N 0.000 claims 1
• KFXZEIZHYRGORN-UHFFFAOYSA-N 2-[[4-methyl-5-(2-methylphenyl)-1,2,4-triazol-3-yl]sulfanyl]-N-(3-nitrophenyl)acetamide Chemical compound CC1=CC=CC=C1C(N1C)=NN=C1SCC(=O)NC1=CC=CC([N+]([O-])=O)=C1 KFXZEIZHYRGORN-UHFFFAOYSA-N 0.000 claims 1
• FLOSBIFEPPSMEE-UHFFFAOYSA-N 2-[[4-methyl-5-(2-methylphenyl)-1,2,4-triazol-3-yl]sulfanyl]-N-[2-(trifluoromethyl)phenyl]acetamide Chemical compound CC1=CC=CC=C1C(N1C)=NN=C1SCC(=O)NC1=CC=CC=C1C(F)(F)F FLOSBIFEPPSMEE-UHFFFAOYSA-N 0.000 claims 1
• PWIVEAIROVLHMI-UHFFFAOYSA-N 2-[[4-methyl-5-(4-nitrophenyl)-1,2,4-triazol-3-yl]sulfanyl]-1-phenylethanone Chemical compound N=1N=C(C=2C=CC(=CC=2)[N+]([O-])=O)N(C)C=1SCC(=O)C1=CC=CC=C1 PWIVEAIROVLHMI-UHFFFAOYSA-N 0.000 claims 1
• FAPYTVIYSGHDBU-UHFFFAOYSA-N 2-[[5-(1-methylpiperidin-2-yl)-4-(2-piperidin-1-ylethyl)-1,2,4-triazol-3-yl]sulfanylmethyl]benzonitrile Chemical compound CN1CCCCC1C(N1CCN2CCCCC2)=NN=C1SCC1=CC=CC=C1C#N FAPYTVIYSGHDBU-UHFFFAOYSA-N 0.000 claims 1
• CKQBSTHOLHFTKJ-UHFFFAOYSA-N 2-[[5-(1-methylpiperidin-2-yl)-4-(2-piperidin-1-ylethyl)-1,2,4-triazol-3-yl]sulfanylmethyl]pyridine Chemical compound CN1CCCCC1C(N1CCN2CCCCC2)=NN=C1SCC1=CC=CC=N1 CKQBSTHOLHFTKJ-UHFFFAOYSA-N 0.000 claims 1
• UFRYQARCQHOJLS-UHFFFAOYSA-N 2-[[5-(2-bromophenyl)-4-ethyl-1,2,4-triazol-3-yl]sulfanyl]-N-(2-methoxy-4-nitrophenyl)acetamide Chemical compound N=1N=C(C=2C(=CC=CC=2)Br)N(CC)C=1SCC(=O)NC1=CC=C([N+]([O-])=O)C=C1OC UFRYQARCQHOJLS-UHFFFAOYSA-N 0.000 claims 1
• YLOGFAIKAQLCEA-UHFFFAOYSA-N 2-[[5-(2-bromophenyl)-4-ethyl-1,2,4-triazol-3-yl]sulfanyl]-N-(2-methyl-4-nitrophenyl)acetamide Chemical compound N=1N=C(C=2C(=CC=CC=2)Br)N(CC)C=1SCC(=O)NC1=CC=C([N+]([O-])=O)C=C1C YLOGFAIKAQLCEA-UHFFFAOYSA-N 0.000 claims 1
• HCDMEXKOPHYLNO-UHFFFAOYSA-N 2-[[5-(2-bromophenyl)-4-ethyl-1,2,4-triazol-3-yl]sulfanyl]-N-(3-chlorophenyl)acetamide Chemical compound N=1N=C(C=2C(=CC=CC=2)Br)N(CC)C=1SCC(=O)NC1=CC=CC(Cl)=C1 HCDMEXKOPHYLNO-UHFFFAOYSA-N 0.000 claims 1
• ZZQKBTYPCCITHB-UHFFFAOYSA-N 2-[[5-(2-bromophenyl)-4-ethyl-1,2,4-triazol-3-yl]sulfanyl]-N-(3-nitrophenyl)acetamide Chemical compound N=1N=C(C=2C(=CC=CC=2)Br)N(CC)C=1SCC(=O)NC1=CC=CC([N+]([O-])=O)=C1 ZZQKBTYPCCITHB-UHFFFAOYSA-N 0.000 claims 1
• SHLVPIKVGDWTGS-UHFFFAOYSA-N 2-[[5-(2-bromophenyl)-4-ethyl-1,2,4-triazol-3-yl]sulfanyl]-N-(4-chlorophenyl)acetamide Chemical compound N=1N=C(C=2C(=CC=CC=2)Br)N(CC)C=1SCC(=O)NC1=CC=C(Cl)C=C1 SHLVPIKVGDWTGS-UHFFFAOYSA-N 0.000 claims 1
• WEHASPBBTYKREO-UHFFFAOYSA-N 2-[[5-(2-bromophenyl)-4-ethyl-1,2,4-triazol-3-yl]sulfanyl]-N-(4-ethoxyphenyl)acetamide Chemical compound C1=CC(OCC)=CC=C1NC(=O)CSC(N1CC)=NN=C1C1=CC=CC=C1Br WEHASPBBTYKREO-UHFFFAOYSA-N 0.000 claims 1
• KYARKZMKUBRZMC-UHFFFAOYSA-N 2-[[5-(2-bromophenyl)-4-ethyl-1,2,4-triazol-3-yl]sulfanyl]-N-(4-fluorophenyl)acetamide Chemical compound N=1N=C(C=2C(=CC=CC=2)Br)N(CC)C=1SCC(=O)NC1=CC=C(F)C=C1 KYARKZMKUBRZMC-UHFFFAOYSA-N 0.000 claims 1
• WXKUZPSDZFKOSP-UHFFFAOYSA-N 2-[[5-(2-bromophenyl)-4-ethyl-1,2,4-triazol-3-yl]sulfanyl]-N-(5-methyl-1,3-thiazol-2-yl)acetamide Chemical compound N=1N=C(C=2C(=CC=CC=2)Br)N(CC)C=1SCC(=O)NC1=NC=C(C)S1 WXKUZPSDZFKOSP-UHFFFAOYSA-N 0.000 claims 1
• TWTIXIDLPLIJOX-UHFFFAOYSA-N 2-[[5-(2-bromophenyl)-4-ethyl-1,2,4-triazol-3-yl]sulfanyl]-N-phenylacetamide Chemical compound N=1N=C(C=2C(=CC=CC=2)Br)N(CC)C=1SCC(=O)NC1=CC=CC=C1 TWTIXIDLPLIJOX-UHFFFAOYSA-N 0.000 claims 1
• SVZLQVRIQHMLHT-UHFFFAOYSA-N 2-[[5-(2-bromophenyl)-4-methyl-1,2,4-triazol-3-yl]sulfanyl]-1-(4-methoxyphenyl)ethanone Chemical compound C1=CC(OC)=CC=C1C(=O)CSC(N1C)=NN=C1C1=CC=CC=C1Br SVZLQVRIQHMLHT-UHFFFAOYSA-N 0.000 claims 1
• JBQPADXCFAJCGV-UHFFFAOYSA-N 2-[[5-(2-bromophenyl)-4-methyl-1,2,4-triazol-3-yl]sulfanyl]-1-(4-methylphenyl)ethanone Chemical compound C1=CC(C)=CC=C1C(=O)CSC(N1C)=NN=C1C1=CC=CC=C1Br JBQPADXCFAJCGV-UHFFFAOYSA-N 0.000 claims 1
• FETKFZVWCWAKQR-UHFFFAOYSA-N 2-[[5-(2-bromophenyl)-4-methyl-1,2,4-triazol-3-yl]sulfanyl]-1-phenylethanone Chemical compound N=1N=C(C=2C(=CC=CC=2)Br)N(C)C=1SCC(=O)C1=CC=CC=C1 FETKFZVWCWAKQR-UHFFFAOYSA-N 0.000 claims 1
• HELJGTBPSSPFOR-UHFFFAOYSA-N 2-[[5-(2-bromophenyl)-4-methyl-1,2,4-triazol-3-yl]sulfanyl]-N-(2,4-dimethylphenyl)acetamide Chemical compound CC1=CC(C)=CC=C1NC(=O)CSC(N1C)=NN=C1C1=CC=CC=C1Br HELJGTBPSSPFOR-UHFFFAOYSA-N 0.000 claims 1
• SABJRBIXAFOGEO-UHFFFAOYSA-N 2-[[5-(2-bromophenyl)-4-methyl-1,2,4-triazol-3-yl]sulfanyl]-N-(2-methoxy-4-nitrophenyl)acetamide Chemical compound COC1=CC([N+]([O-])=O)=CC=C1NC(=O)CSC(N1C)=NN=C1C1=CC=CC=C1Br SABJRBIXAFOGEO-UHFFFAOYSA-N 0.000 claims 1
• WAQZRXHCAAWDCA-UHFFFAOYSA-N 2-[[5-(2-bromophenyl)-4-methyl-1,2,4-triazol-3-yl]sulfanyl]-N-(2-methyl-4-nitrophenyl)acetamide Chemical compound CC1=CC([N+]([O-])=O)=CC=C1NC(=O)CSC(N1C)=NN=C1C1=CC=CC=C1Br WAQZRXHCAAWDCA-UHFFFAOYSA-N 0.000 claims 1
• BRXDYKZYNOWVMK-UHFFFAOYSA-N 2-[[5-(2-bromophenyl)-4-methyl-1,2,4-triazol-3-yl]sulfanyl]-N-(2-nitrophenyl)acetamide Chemical compound N=1N=C(C=2C(=CC=CC=2)Br)N(C)C=1SCC(=O)NC1=CC=CC=C1[N+]([O-])=O BRXDYKZYNOWVMK-UHFFFAOYSA-N 0.000 claims 1
• GATPLZCGJPIMHP-UHFFFAOYSA-N 2-[[5-(2-bromophenyl)-4-methyl-1,2,4-triazol-3-yl]sulfanyl]-N-(3,4-dimethylphenyl)acetamide Chemical compound C1=C(C)C(C)=CC=C1NC(=O)CSC(N1C)=NN=C1C1=CC=CC=C1Br GATPLZCGJPIMHP-UHFFFAOYSA-N 0.000 claims 1
• PGSKPNBHMBZIKJ-UHFFFAOYSA-N 2-[[5-(2-bromophenyl)-4-methyl-1,2,4-triazol-3-yl]sulfanyl]-N-(4-chlorophenyl)acetamide Chemical compound N=1N=C(C=2C(=CC=CC=2)Br)N(C)C=1SCC(=O)NC1=CC=C(Cl)C=C1 PGSKPNBHMBZIKJ-UHFFFAOYSA-N 0.000 claims 1
• QRIGJSWJABHUHD-UHFFFAOYSA-N 2-[[5-(2-bromophenyl)-4-methyl-1,2,4-triazol-3-yl]sulfanyl]-N-(4-ethoxyphenyl)acetamide Chemical compound C1=CC(OCC)=CC=C1NC(=O)CSC(N1C)=NN=C1C1=CC=CC=C1Br QRIGJSWJABHUHD-UHFFFAOYSA-N 0.000 claims 1
• LWQCJALZMRSYMG-UHFFFAOYSA-N 2-[[5-(2-bromophenyl)-4-methyl-1,2,4-triazol-3-yl]sulfanyl]-N-(4-fluorophenyl)acetamide Chemical compound N=1N=C(C=2C(=CC=CC=2)Br)N(C)C=1SCC(=O)NC1=CC=C(F)C=C1 LWQCJALZMRSYMG-UHFFFAOYSA-N 0.000 claims 1
• WKYBKAUYZQWGLB-UHFFFAOYSA-N 2-[[5-(2-bromophenyl)-4-methyl-1,2,4-triazol-3-yl]sulfanyl]-N-(4-methoxy-2-nitrophenyl)acetamide Chemical compound [O-][N+](=O)C1=CC(OC)=CC=C1NC(=O)CSC(N1C)=NN=C1C1=CC=CC=C1Br WKYBKAUYZQWGLB-UHFFFAOYSA-N 0.000 claims 1
• GUSIXBSKJSZOEB-UHFFFAOYSA-N 2-[[5-(2-bromophenyl)-4-methyl-1,2,4-triazol-3-yl]sulfanyl]-N-(4-methoxyphenyl)acetamide Chemical compound C1=CC(OC)=CC=C1NC(=O)CSC(N1C)=NN=C1C1=CC=CC=C1Br GUSIXBSKJSZOEB-UHFFFAOYSA-N 0.000 claims 1
• FAZNPJNSPSJNJH-UHFFFAOYSA-N 2-[[5-(2-bromophenyl)-4-methyl-1,2,4-triazol-3-yl]sulfanyl]-N-(4-methyl-3-nitrophenyl)acetamide Chemical compound C1=C([N+]([O-])=O)C(C)=CC=C1NC(=O)CSC(N1C)=NN=C1C1=CC=CC=C1Br FAZNPJNSPSJNJH-UHFFFAOYSA-N 0.000 claims 1
• GELQXPCHVGBPDW-UHFFFAOYSA-N 2-[[5-(2-bromophenyl)-4-methyl-1,2,4-triazol-3-yl]sulfanyl]-N-(4-nitrophenyl)acetamide Chemical compound N=1N=C(C=2C(=CC=CC=2)Br)N(C)C=1SCC(=O)NC1=CC=C([N+]([O-])=O)C=C1 GELQXPCHVGBPDW-UHFFFAOYSA-N 0.000 claims 1
• GWZIEMOFXWUWDO-UHFFFAOYSA-N 2-[[5-(2-bromophenyl)-4-methyl-1,2,4-triazol-3-yl]sulfanyl]-N-(4-phenyl-1,3-thiazol-2-yl)acetamide Chemical compound N=1N=C(C=2C(=CC=CC=2)Br)N(C)C=1SCC(=O)NC(SC=1)=NC=1C1=CC=CC=C1 GWZIEMOFXWUWDO-UHFFFAOYSA-N 0.000 claims 1
• URABVVBXBUHRMV-UHFFFAOYSA-N 2-[[5-(2-bromophenyl)-4-methyl-1,2,4-triazol-3-yl]sulfanyl]-N-phenylacetamide Chemical compound N=1N=C(C=2C(=CC=CC=2)Br)N(C)C=1SCC(=O)NC1=CC=CC=C1 URABVVBXBUHRMV-UHFFFAOYSA-N 0.000 claims 1
• OYVBBUOUCSKWQB-UHFFFAOYSA-N 2-[[5-(2-bromophenyl)-4-methyl-1,2,4-triazol-3-yl]sulfanyl]acetonitrile Chemical compound CN1C(SCC#N)=NN=C1C1=CC=CC=C1Br OYVBBUOUCSKWQB-UHFFFAOYSA-N 0.000 claims 1
• UXSZJHIIHHDUSB-UHFFFAOYSA-N 2-[[5-(2-methoxyphenyl)-4-(2-piperidin-1-ylethyl)-1,2,4-triazol-3-yl]sulfanylmethyl]benzonitrile Chemical compound COC1=CC=CC=C1C(N1CCN2CCCCC2)=NN=C1SCC1=CC=CC=C1C#N UXSZJHIIHHDUSB-UHFFFAOYSA-N 0.000 claims 1
• CGLFOHHBGQZPDV-UHFFFAOYSA-N 2-[[5-(2-methoxyphenyl)-4-(2-piperidin-1-ylethyl)-1,2,4-triazol-3-yl]sulfanylmethyl]pyridine Chemical compound COC1=CC=CC=C1C(N1CCN2CCCCC2)=NN=C1SCC1=CC=CC=N1 CGLFOHHBGQZPDV-UHFFFAOYSA-N 0.000 claims 1
• PEQZAKUKKNVNBD-UHFFFAOYSA-N 2-[[5-(2-methoxyphenyl)-4-(3-methoxypropyl)-1,2,4-triazol-3-yl]sulfanylmethyl]benzonitrile Chemical compound N=1N=C(C=2C(=CC=CC=2)OC)N(CCCOC)C=1SCC1=CC=CC=C1C#N PEQZAKUKKNVNBD-UHFFFAOYSA-N 0.000 claims 1
• OJNMVRPPGJZYPO-UHFFFAOYSA-N 2-[[5-(2-methoxyphenyl)-4-(3-methoxypropyl)-1,2,4-triazol-3-yl]sulfanylmethyl]pyridine Chemical compound N=1N=C(C=2C(=CC=CC=2)OC)N(CCCOC)C=1SCC1=CC=CC=N1 OJNMVRPPGJZYPO-UHFFFAOYSA-N 0.000 claims 1
• SHJNHIBXDMEPLY-UHFFFAOYSA-N 2-[[5-(2-methoxyphenyl)-4-methyl-1,2,4-triazol-3-yl]sulfanyl]-N-(4-phenyl-1,3-thiazol-2-yl)acetamide Chemical compound COC1=CC=CC=C1C(N1C)=NN=C1SCC(=O)NC1=NC(C=2C=CC=CC=2)=CS1 SHJNHIBXDMEPLY-UHFFFAOYSA-N 0.000 claims 1
• OGSLKFCZCQXWPQ-UHFFFAOYSA-N 2-[[5-(3,4-dimethoxyphenyl)-4-methyl-1,2,4-triazol-3-yl]sulfanyl]-1-(4-methylphenyl)ethanone Chemical compound C1=C(OC)C(OC)=CC=C1C(N1C)=NN=C1SCC(=O)C1=CC=C(C)C=C1 OGSLKFCZCQXWPQ-UHFFFAOYSA-N 0.000 claims 1
• NAJXTAVJEPPUBU-UHFFFAOYSA-N 2-[[5-(4-chlorophenyl)-4-ethyl-1,2,4-triazol-3-yl]sulfanyl]-N-(2-nitrophenyl)acetamide Chemical compound N=1N=C(C=2C=CC(Cl)=CC=2)N(CC)C=1SCC(=O)NC1=CC=CC=C1[N+]([O-])=O NAJXTAVJEPPUBU-UHFFFAOYSA-N 0.000 claims 1
• NYQWFYGDQFLCAP-UHFFFAOYSA-N 2-[[5-(4-methoxyphenyl)-4-methyl-1,2,4-triazol-3-yl]sulfanyl]-1-phenylethanone Chemical compound C1=CC(OC)=CC=C1C(N1C)=NN=C1SCC(=O)C1=CC=CC=C1 NYQWFYGDQFLCAP-UHFFFAOYSA-N 0.000 claims 1
• OPFXBHWKOCLSKY-UHFFFAOYSA-N 2-[[5-(furan-2-yl)-4-(2-phenylethyl)-1,2,4-triazol-3-yl]sulfanyl]-1-(4-methoxyphenyl)ethanone Chemical compound C1=CC(OC)=CC=C1C(=O)CSC(N1CCC=2C=CC=CC=2)=NN=C1C1=CC=CO1 OPFXBHWKOCLSKY-UHFFFAOYSA-N 0.000 claims 1
• XTYOJFSKTHKIEI-UHFFFAOYSA-N 2-[[5-(furan-2-yl)-4-(2-phenylethyl)-1,2,4-triazol-3-yl]sulfanyl]-1-(4-methylsulfonylphenyl)ethanone Chemical compound C1=CC(S(=O)(=O)C)=CC=C1C(=O)CSC(N1CCC=2C=CC=CC=2)=NN=C1C1=CC=CO1 XTYOJFSKTHKIEI-UHFFFAOYSA-N 0.000 claims 1
• CXJQKXSQGVQKGW-UHFFFAOYSA-N 2-[[5-(furan-2-yl)-4-(2-phenylethyl)-1,2,4-triazol-3-yl]sulfanyl]-1-phenylethanone Chemical compound C=1C=CC=CC=1C(=O)CSC(N1CCC=2C=CC=CC=2)=NN=C1C1=CC=CO1 CXJQKXSQGVQKGW-UHFFFAOYSA-N 0.000 claims 1
• ZYWKLTOIYSZYEN-UHFFFAOYSA-N 2-[[5-(furan-2-yl)-4-(2-phenylethyl)-1,2,4-triazol-3-yl]sulfanyl]-1-pyridin-3-ylethanone Chemical compound C=1C=CN=CC=1C(=O)CSC(N1CCC=2C=CC=CC=2)=NN=C1C1=CC=CO1 ZYWKLTOIYSZYEN-UHFFFAOYSA-N 0.000 claims 1
• ZWRVAIVKHFVXLJ-UHFFFAOYSA-N 2-[[5-[(2,4-dimethylanilino)methyl]-4-(furan-2-ylmethyl)-1,2,4-triazol-3-yl]sulfanyl]-1-phenylethanone Chemical compound CC1=CC(C)=CC=C1NCC(N1CC=2OC=CC=2)=NN=C1SCC(=O)C1=CC=CC=C1 ZWRVAIVKHFVXLJ-UHFFFAOYSA-N 0.000 claims 1
• QHYXIAHWDAHWPW-UHFFFAOYSA-N 2-[[5-[(2,4-dimethylanilino)methyl]-4-(oxolan-2-ylmethyl)-1,2,4-triazol-3-yl]sulfanyl]-1-(4-methylphenyl)ethanone Chemical compound C1=CC(C)=CC=C1C(=O)CSC(N1CC2OCCC2)=NN=C1CNC1=CC=C(C)C=C1C QHYXIAHWDAHWPW-UHFFFAOYSA-N 0.000 claims 1
• WPRUYJYBJUPTHW-UHFFFAOYSA-N 2-[[5-[(2,4-dimethylanilino)methyl]-4-ethyl-1,2,4-triazol-3-yl]sulfanyl]-1-(4-methoxyphenyl)ethanone Chemical compound N=1N=C(SCC(=O)C=2C=CC(OC)=CC=2)N(CC)C=1CNC1=CC=C(C)C=C1C WPRUYJYBJUPTHW-UHFFFAOYSA-N 0.000 claims 1
• IRJDZKVQPLBCAH-UHFFFAOYSA-N 2-[[5-[(2,4-dimethylanilino)methyl]-4-ethyl-1,2,4-triazol-3-yl]sulfanyl]-1-(4-methylphenyl)ethanone Chemical compound N=1N=C(SCC(=O)C=2C=CC(C)=CC=2)N(CC)C=1CNC1=CC=C(C)C=C1C IRJDZKVQPLBCAH-UHFFFAOYSA-N 0.000 claims 1
• OYQWGMUQQMULAY-UHFFFAOYSA-N 2-[[5-[(2,6-dimethylanilino)methyl]-4-methyl-1,2,4-triazol-3-yl]sulfanyl]-1-phenylethanone Chemical compound CC1=CC=CC(C)=C1NCC(N1C)=NN=C1SCC(=O)C1=CC=CC=C1 OYQWGMUQQMULAY-UHFFFAOYSA-N 0.000 claims 1
• QTJULHBXGMEAFM-UHFFFAOYSA-N 2-[[5-[(2-chloroanilino)methyl]-4-ethyl-1,2,4-triazol-3-yl]sulfanyl]-1-(4-chlorophenyl)ethanone Chemical compound N=1N=C(SCC(=O)C=2C=CC(Cl)=CC=2)N(CC)C=1CNC1=CC=CC=C1Cl QTJULHBXGMEAFM-UHFFFAOYSA-N 0.000 claims 1
• JTTPJDWITVUZEN-UHFFFAOYSA-N 2-[[5-[(2-chloroanilino)methyl]-4-ethyl-1,2,4-triazol-3-yl]sulfanyl]-1-piperidin-1-ylethanone Chemical compound N=1N=C(SCC(=O)N2CCCCC2)N(CC)C=1CNC1=CC=CC=C1Cl JTTPJDWITVUZEN-UHFFFAOYSA-N 0.000 claims 1
• ZJLYVQFVBUOBID-UHFFFAOYSA-N 2-[[5-[(3-chloroanilino)methyl]-4-ethyl-1,2,4-triazol-3-yl]sulfanyl]-1-phenylethanone Chemical compound N=1N=C(SCC(=O)C=2C=CC=CC=2)N(CC)C=1CNC1=CC=CC(Cl)=C1 ZJLYVQFVBUOBID-UHFFFAOYSA-N 0.000 claims 1
• BVMKIXYQLRDAJV-UHFFFAOYSA-N 2-[[5-[(4-chloroanilino)methyl]-4-ethyl-1,2,4-triazol-3-yl]sulfanyl]-N-(2-nitrophenyl)acetamide Chemical compound N=1N=C(SCC(=O)NC=2C(=CC=CC=2)[N+]([O-])=O)N(CC)C=1CNC1=CC=C(Cl)C=C1 BVMKIXYQLRDAJV-UHFFFAOYSA-N 0.000 claims 1
• LYTPZVQQHMBXPY-UHFFFAOYSA-N 2-[[5-[(4-chlorophenyl)methylsulfanyl]-4-methyl-1,2,4-triazol-3-yl]methyl]-4H-1,4-benzothiazin-3-one Chemical compound CN1C(CC2C(NC3=CC=CC=C3S2)=O)=NN=C1SCC1=CC=C(Cl)C=C1 LYTPZVQQHMBXPY-UHFFFAOYSA-N 0.000 claims 1
• MLMSYHUAHMVHCI-UHFFFAOYSA-N 2-[[5-[(4-fluoroanilino)methyl]-4-(oxolan-2-ylmethyl)-1,2,4-triazol-3-yl]sulfanyl]-1-(4-methylphenyl)ethanone Chemical compound C1=CC(C)=CC=C1C(=O)CSC(N1CC2OCCC2)=NN=C1CNC1=CC=C(F)C=C1 MLMSYHUAHMVHCI-UHFFFAOYSA-N 0.000 claims 1
• LFLDRGOWTWLONP-UHFFFAOYSA-N 2-[[5-[(4-fluoroanilino)methyl]-4-methyl-1,2,4-triazol-3-yl]sulfanyl]-1-phenylethanone Chemical compound N=1N=C(SCC(=O)C=2C=CC=CC=2)N(C)C=1CNC1=CC=C(F)C=C1 LFLDRGOWTWLONP-UHFFFAOYSA-N 0.000 claims 1
• FYUOVOZPWYCNEI-UHFFFAOYSA-N 2-[[5-[(4-methoxyphenoxy)methyl]-4-methyl-1,2,4-triazol-3-yl]sulfanyl]-1-(4-methoxyphenyl)ethanone Chemical compound C1=CC(OC)=CC=C1OCC(N1C)=NN=C1SCC(=O)C1=CC=C(OC)C=C1 FYUOVOZPWYCNEI-UHFFFAOYSA-N 0.000 claims 1
• IQMVOMLBQSAEMN-UHFFFAOYSA-N 2-[[5-[(4-methoxyphenoxy)methyl]-4-methyl-1,2,4-triazol-3-yl]sulfanyl]-1-phenylethanone Chemical compound C1=CC(OC)=CC=C1OCC(N1C)=NN=C1SCC(=O)C1=CC=CC=C1 IQMVOMLBQSAEMN-UHFFFAOYSA-N 0.000 claims 1
• MAAPPOOZMSSYGW-UHFFFAOYSA-N 2-[[5-methyl-4-(2-phenylethyl)-1,2,4-triazol-3-yl]sulfanyl]-N-[3-(trifluoromethyl)phenyl]acetamide Chemical compound C=1C=CC=CC=1CCN1C(C)=NN=C1SCC(=O)NC1=CC=CC(C(F)(F)F)=C1 MAAPPOOZMSSYGW-UHFFFAOYSA-N 0.000 claims 1
• PMDUBZQXBMFHGE-UHFFFAOYSA-N 2-[[5-methyl-4-(2-phenylethyl)-1,2,4-triazol-3-yl]sulfanyl]-N-naphthalen-1-ylacetamide Chemical compound CC1=NN=C(SCC(=O)NC=2C3=CC=CC=C3C=CC=2)N1CCC1=CC=CC=C1 PMDUBZQXBMFHGE-UHFFFAOYSA-N 0.000 claims 1
• OZWREHMIMBUIBW-UHFFFAOYSA-N 2-[[5-methyl-4-(2-phenylethyl)-1,2,4-triazol-3-yl]sulfanyl]-N-phenylacetamide Chemical compound C=1C=CC=CC=1CCN1C(C)=NN=C1SCC(=O)NC1=CC=CC=C1 OZWREHMIMBUIBW-UHFFFAOYSA-N 0.000 claims 1
• BVXDLQQFAPDQKW-UHFFFAOYSA-N 2-[[5-phenyl-4-(2-phenylethyl)-1,2,4-triazol-3-yl]sulfanyl]-1-pyridin-3-ylethanone Chemical compound C=1C=CN=CC=1C(=O)CSC(N1CCC=2C=CC=CC=2)=NN=C1C1=CC=CC=C1 BVXDLQQFAPDQKW-UHFFFAOYSA-N 0.000 claims 1
• IXVDGRUBVVVBSB-UHFFFAOYSA-N 2-benzylsulfanyl-N-[2-(2-methoxyphenoxy)ethyl]acetamide Chemical compound COC1=CC=CC=C1OCCNC(=O)CSCC1=CC=CC=C1 IXVDGRUBVVVBSB-UHFFFAOYSA-N 0.000 claims 1
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• AEGHNVIUXMRJME-UHFFFAOYSA-N 3-(1,3-benzodioxol-5-yl)-3-(2-methoxyphenyl)-1-pyrrolidin-1-ylpropan-1-one Chemical compound COC1=CC=CC=C1C(C=1C=C2OCOC2=CC=1)CC(=O)N1CCCC1 AEGHNVIUXMRJME-UHFFFAOYSA-N 0.000 claims 1
• SQUUWDKKCXOUFN-UHFFFAOYSA-N 3-(1,3-benzodioxol-5-yl)-4-ethyl-5-[(2-nitrophenyl)methylsulfanyl]-1,2,4-triazole Chemical compound N=1N=C(C=2C=C3OCOC3=CC=2)N(CC)C=1SCC1=CC=CC=C1[N+]([O-])=O SQUUWDKKCXOUFN-UHFFFAOYSA-N 0.000 claims 1
• APYSFURDEKPNPG-UHFFFAOYSA-N 3-(1,3-benzodioxol-5-yl)-4-ethyl-5-[(4-methoxyphenyl)methylsulfanyl]-1,2,4-triazole Chemical compound N=1N=C(C=2C=C3OCOC3=CC=2)N(CC)C=1SCC1=CC=C(OC)C=C1 APYSFURDEKPNPG-UHFFFAOYSA-N 0.000 claims 1
• SWPSVWPGUSAAQP-UHFFFAOYSA-N 3-(1,3-benzodioxol-5-yl)-4-ethyl-5-[(4-methylsulfonylphenyl)methylsulfanyl]-1,2,4-triazole Chemical compound N=1N=C(C=2C=C3OCOC3=CC=2)N(CC)C=1SCC1=CC=C(S(C)(=O)=O)C=C1 SWPSVWPGUSAAQP-UHFFFAOYSA-N 0.000 claims 1
• XAKXVZZICHTUGW-UHFFFAOYSA-N 3-(1,3-benzodioxol-5-yl)-4-ethyl-5-[(4-phenylmethoxyphenyl)methylsulfanyl]-1,2,4-triazole Chemical compound N=1N=C(C=2C=C3OCOC3=CC=2)N(CC)C=1SCC(C=C1)=CC=C1OCC1=CC=CC=C1 XAKXVZZICHTUGW-UHFFFAOYSA-N 0.000 claims 1
• VACLYSBTPLBLMK-UHFFFAOYSA-N 3-(1,3-benzodioxol-5-yl)-4-ethyl-5-[(5-methyl-2-nitrophenyl)methylsulfanyl]-1,2,4-triazole Chemical compound N=1N=C(C=2C=C3OCOC3=CC=2)N(CC)C=1SCC1=CC(C)=CC=C1[N+]([O-])=O VACLYSBTPLBLMK-UHFFFAOYSA-N 0.000 claims 1
• JKKYVKCAZRJCRX-UHFFFAOYSA-N 3-(1,3-benzodioxol-5-yl)-4-ethyl-5-[[4-(trifluoromethoxy)phenyl]methylsulfanyl]-1,2,4-triazole Chemical compound N=1N=C(C=2C=C3OCOC3=CC=2)N(CC)C=1SCC1=CC=C(OC(F)(F)F)C=C1 JKKYVKCAZRJCRX-UHFFFAOYSA-N 0.000 claims 1
• VDPYERUAJIQQRJ-UHFFFAOYSA-N 3-(1,3-benzodioxol-5-yl)-5-(cyclohexylmethylsulfanyl)-4-ethyl-1,2,4-triazole Chemical compound N=1N=C(C=2C=C3OCOC3=CC=2)N(CC)C=1SCC1CCCCC1 VDPYERUAJIQQRJ-UHFFFAOYSA-N 0.000 claims 1
• BKRAEGKYBYPRRF-UHFFFAOYSA-N 3-(1,3-benzodioxol-5-yl)-5-[(2,4-dichlorophenyl)methylsulfanyl]-4-ethyl-1,2,4-triazole Chemical compound N=1N=C(C=2C=C3OCOC3=CC=2)N(CC)C=1SCC1=CC=C(Cl)C=C1Cl BKRAEGKYBYPRRF-UHFFFAOYSA-N 0.000 claims 1
• RHPXENSHHDVUSA-UHFFFAOYSA-N 3-(1,3-benzodioxol-5-yl)-5-[(2,6-dichlorophenyl)methylsulfanyl]-4-ethyl-1,2,4-triazole Chemical compound N=1N=C(C=2C=C3OCOC3=CC=2)N(CC)C=1SCC1=C(Cl)C=CC=C1Cl RHPXENSHHDVUSA-UHFFFAOYSA-N 0.000 claims 1
• ALUDBMDJTAIHFW-UHFFFAOYSA-N 3-(1,3-benzodioxol-5-yl)-5-[(2-chlorophenyl)methylsulfanyl]-4-ethyl-1,2,4-triazole Chemical compound N=1N=C(C=2C=C3OCOC3=CC=2)N(CC)C=1SCC1=CC=CC=C1Cl ALUDBMDJTAIHFW-UHFFFAOYSA-N 0.000 claims 1
• IPONEIAWWGEKND-UHFFFAOYSA-N 3-(1,3-benzodioxol-5-yl)-5-[(3,5-dimethoxyphenyl)methylsulfanyl]-4-ethyl-1,2,4-triazole Chemical compound N=1N=C(C=2C=C3OCOC3=CC=2)N(CC)C=1SCC1=CC(OC)=CC(OC)=C1 IPONEIAWWGEKND-UHFFFAOYSA-N 0.000 claims 1
• IIAIJBPOOLHYLV-UHFFFAOYSA-N 3-(1,3-benzodioxol-5-yl)-5-[(4-bromophenyl)methylsulfanyl]-4-ethyl-1,2,4-triazole Chemical compound N=1N=C(C=2C=C3OCOC3=CC=2)N(CC)C=1SCC1=CC=C(Br)C=C1 IIAIJBPOOLHYLV-UHFFFAOYSA-N 0.000 claims 1
• JUNRCDSERGLGRF-UHFFFAOYSA-N 3-(1,3-benzodioxol-5-yl)-5-[(6-chloro-1,3-benzodioxol-5-yl)methylsulfanyl]-4-ethyl-1,2,4-triazole Chemical compound C1=C2OCOC2=CC(C2=NN=C(SCC=3C(=CC=4OCOC=4C=3)Cl)N2CC)=C1 JUNRCDSERGLGRF-UHFFFAOYSA-N 0.000 claims 1
• IZVZFYJEVTWHHM-UHFFFAOYSA-N 3-(1,3-dioxoisoindol-2-yl)-N-(2-methylcyclohexyl)propanamide Chemical compound CC1CCCCC1NC(=O)CCN1C(=O)C2=CC=CC=C2C1=O IZVZFYJEVTWHHM-UHFFFAOYSA-N 0.000 claims 1
• FDHALABOVMMWHS-UHFFFAOYSA-N 3-(1-benzothiophen-2-yl)-4-ethyl-5-[(2-nitrophenyl)methylsulfanyl]-1,2,4-triazole Chemical compound N=1N=C(C=2SC3=CC=CC=C3C=2)N(CC)C=1SCC1=CC=CC=C1[N+]([O-])=O FDHALABOVMMWHS-UHFFFAOYSA-N 0.000 claims 1
• QSZRMSSHWVTXMK-UHFFFAOYSA-N 3-(1-benzothiophen-2-yl)-4-ethyl-5-[(3-nitrophenyl)methylsulfanyl]-1,2,4-triazole Chemical compound N=1N=C(C=2SC3=CC=CC=C3C=2)N(CC)C=1SCC1=CC=CC([N+]([O-])=O)=C1 QSZRMSSHWVTXMK-UHFFFAOYSA-N 0.000 claims 1
• MMOJEUZXXNJMSE-UHFFFAOYSA-N 3-(1-benzothiophen-2-yl)-4-ethyl-5-[(4-methoxyphenyl)methylsulfanyl]-1,2,4-triazole Chemical compound N=1N=C(C=2SC3=CC=CC=C3C=2)N(CC)C=1SCC1=CC=C(OC)C=C1 MMOJEUZXXNJMSE-UHFFFAOYSA-N 0.000 claims 1
• QZFFKLBSOVYAFA-UHFFFAOYSA-N 3-(1-benzothiophen-2-yl)-4-ethyl-5-[(4-nitrophenyl)methylsulfanyl]-1,2,4-triazole Chemical compound N=1N=C(C=2SC3=CC=CC=C3C=2)N(CC)C=1SCC1=CC=C([N+]([O-])=O)C=C1 QZFFKLBSOVYAFA-UHFFFAOYSA-N 0.000 claims 1
• ICWYPJGIOFEUFW-UHFFFAOYSA-N 3-(1-benzothiophen-2-yl)-4-ethyl-5-[(4-phenylmethoxyphenyl)methylsulfanyl]-1,2,4-triazole Chemical compound N=1N=C(C=2SC3=CC=CC=C3C=2)N(CC)C=1SCC(C=C1)=CC=C1OCC1=CC=CC=C1 ICWYPJGIOFEUFW-UHFFFAOYSA-N 0.000 claims 1
• FOIPLQZASNTOMD-UHFFFAOYSA-N 3-(1-benzothiophen-2-yl)-4-ethyl-5-[[3-(trifluoromethoxy)phenyl]methylsulfanyl]-1,2,4-triazole Chemical compound N=1N=C(C=2SC3=CC=CC=C3C=2)N(CC)C=1SCC1=CC=CC(OC(F)(F)F)=C1 FOIPLQZASNTOMD-UHFFFAOYSA-N 0.000 claims 1
• CTULBSGKGGOXEI-UHFFFAOYSA-N 3-(1-benzothiophen-2-yl)-5-[(2-chlorophenyl)methylsulfanyl]-4-ethyl-1,2,4-triazole Chemical compound N=1N=C(C=2SC3=CC=CC=C3C=2)N(CC)C=1SCC1=CC=CC=C1Cl CTULBSGKGGOXEI-UHFFFAOYSA-N 0.000 claims 1
• LZWGTGSDCKNULB-UHFFFAOYSA-N 3-(1-benzothiophen-2-yl)-5-[(4-bromophenyl)methylsulfanyl]-4-ethyl-1,2,4-triazole Chemical compound N=1N=C(C=2SC3=CC=CC=C3C=2)N(CC)C=1SCC1=CC=C(Br)C=C1 LZWGTGSDCKNULB-UHFFFAOYSA-N 0.000 claims 1
• QWOZYRJMINCFCO-UHFFFAOYSA-N 3-(1-benzothiophen-2-yl)-5-[(6-chloro-1,3-benzodioxol-5-yl)methylsulfanyl]-4-ethyl-1,2,4-triazole Chemical compound C1=CC=C2SC(C3=NN=C(SCC=4C(=CC=5OCOC=5C=4)Cl)N3CC)=CC2=C1 QWOZYRJMINCFCO-UHFFFAOYSA-N 0.000 claims 1
• OKOUKEMKLYMBMZ-UHFFFAOYSA-N 3-(1-benzylimidazol-2-yl)sulfanyl-N-cyclohexylpropanamide Chemical compound C1CCCCC1NC(=O)CCSC1=NC=CN1CC1=CC=CC=C1 OKOUKEMKLYMBMZ-UHFFFAOYSA-N 0.000 claims 1
• LLUHQFWZRQUSJD-UHFFFAOYSA-N 3-(2,4-dichlorophenyl)-4-(2-methylprop-2-enyl)-1H-1,2,4-triazole-5-thione Chemical compound N1C(=S)N(CC(=C)C)C(C=2C(=CC(Cl)=CC=2)Cl)=N1 LLUHQFWZRQUSJD-UHFFFAOYSA-N 0.000 claims 1
• CHVNFDHQTPIKSU-UHFFFAOYSA-N 3-(2,4-dichlorophenyl)-4-(furan-2-ylmethyl)-5-methylsulfanyl-1,2,4-triazole Chemical compound C=1C=COC=1CN1C(SC)=NN=C1C1=CC=C(Cl)C=C1Cl CHVNFDHQTPIKSU-UHFFFAOYSA-N 0.000 claims 1
• JMUBCVRQTQJXDS-UHFFFAOYSA-N 3-(2,4-dichlorophenyl)-4-prop-2-enyl-1H-1,2,4-triazole-5-thione Chemical compound ClC1=CC(Cl)=CC=C1C1=NNC(=S)N1CC=C JMUBCVRQTQJXDS-UHFFFAOYSA-N 0.000 claims 1
• NJQBEFPUXBYGQT-UHFFFAOYSA-N 3-(2,4-dichlorophenyl)-5,5-dimethyl-6H-[1,2,4]triazolo[3,4-a]isoquinoline Chemical compound N12C(C)(C)CC3=CC=CC=C3C2=NN=C1C1=CC=C(Cl)C=C1Cl NJQBEFPUXBYGQT-UHFFFAOYSA-N 0.000 claims 1
• FTQFYENWBZENCJ-UHFFFAOYSA-N 3-(2,4-dichlorophenyl)-6,6-dimethyl-5,7-dihydro-1H-[1,2,4]triazolo[4,3-a]pyrimidine Chemical compound N12CC(C)(C)CNC2=NN=C1C1=CC=C(Cl)C=C1Cl FTQFYENWBZENCJ-UHFFFAOYSA-N 0.000 claims 1
• NGKOMQXOGMMMDI-UHFFFAOYSA-N 3-(2-bromophenyl)-4-ethyl-5-[(3-nitrophenyl)methylsulfanyl]-1,2,4-triazole Chemical compound N=1N=C(C=2C(=CC=CC=2)Br)N(CC)C=1SCC1=CC=CC([N+]([O-])=O)=C1 NGKOMQXOGMMMDI-UHFFFAOYSA-N 0.000 claims 1
• DUGZVFHBSSQHDR-UHFFFAOYSA-N 3-(2-bromophenyl)-4-ethyl-5-[(4-methoxyphenyl)methylsulfanyl]-1,2,4-triazole Chemical compound N=1N=C(C=2C(=CC=CC=2)Br)N(CC)C=1SCC1=CC=C(OC)C=C1 DUGZVFHBSSQHDR-UHFFFAOYSA-N 0.000 claims 1
• GEZSCPVDYAUXGS-UHFFFAOYSA-N 3-(2-bromophenyl)-4-ethyl-5-[(4-phenylmethoxyphenyl)methylsulfanyl]-1,2,4-triazole Chemical compound N=1N=C(C=2C(=CC=CC=2)Br)N(CC)C=1SCC(C=C1)=CC=C1OCC1=CC=CC=C1 GEZSCPVDYAUXGS-UHFFFAOYSA-N 0.000 claims 1
• UBQQVQBPMGUXRO-UHFFFAOYSA-N 3-(2-bromophenyl)-4-ethyl-5-[(5-methyl-2-nitrophenyl)methylsulfanyl]-1,2,4-triazole Chemical compound N=1N=C(C=2C(=CC=CC=2)Br)N(CC)C=1SCC1=CC(C)=CC=C1[N+]([O-])=O UBQQVQBPMGUXRO-UHFFFAOYSA-N 0.000 claims 1
• NBHVEICNYXNJOF-UHFFFAOYSA-N 3-(2-bromophenyl)-4-ethyl-5-[[4-(trifluoromethoxy)phenyl]methylsulfanyl]-1,2,4-triazole Chemical compound N=1N=C(C=2C(=CC=CC=2)Br)N(CC)C=1SCC1=CC=C(OC(F)(F)F)C=C1 NBHVEICNYXNJOF-UHFFFAOYSA-N 0.000 claims 1
• YEHRMYOEQVKBRI-UHFFFAOYSA-N 3-(2-bromophenyl)-4-ethyl-5-[[4-(trifluoromethyl)phenyl]methylsulfanyl]-1,2,4-triazole Chemical compound N=1N=C(C=2C(=CC=CC=2)Br)N(CC)C=1SCC1=CC=C(C(F)(F)F)C=C1 YEHRMYOEQVKBRI-UHFFFAOYSA-N 0.000 claims 1
• AZRJXKPEGSURNN-UHFFFAOYSA-N 3-(2-bromophenyl)-4-methyl-5-[(4-nitrophenyl)methylsulfanyl]-1,2,4-triazole Chemical compound N=1N=C(C=2C(=CC=CC=2)Br)N(C)C=1SCC1=CC=C([N+]([O-])=O)C=C1 AZRJXKPEGSURNN-UHFFFAOYSA-N 0.000 claims 1
• VARJRQAJBOVJFZ-UHFFFAOYSA-N 3-(2-bromophenyl)-5-(cyclohexylmethylsulfanyl)-4-ethyl-1,2,4-triazole Chemical compound N=1N=C(C=2C(=CC=CC=2)Br)N(CC)C=1SCC1CCCCC1 VARJRQAJBOVJFZ-UHFFFAOYSA-N 0.000 claims 1
• FHFRKPQUXFCTNG-UHFFFAOYSA-N 3-(2-bromophenyl)-5-[(2,4-dichlorophenyl)methylsulfanyl]-4-ethyl-1,2,4-triazole Chemical compound N=1N=C(C=2C(=CC=CC=2)Br)N(CC)C=1SCC1=CC=C(Cl)C=C1Cl FHFRKPQUXFCTNG-UHFFFAOYSA-N 0.000 claims 1
• JUJJGFAJRCMMPX-UHFFFAOYSA-N 3-(2-bromophenyl)-5-[(2-chlorophenyl)methylsulfanyl]-4-ethyl-1,2,4-triazole Chemical compound N=1N=C(C=2C(=CC=CC=2)Br)N(CC)C=1SCC1=CC=CC=C1Cl JUJJGFAJRCMMPX-UHFFFAOYSA-N 0.000 claims 1
• WODFFZGITLJNLS-UHFFFAOYSA-N 3-(2-bromophenyl)-5-[(3,4-dichlorophenyl)methylsulfanyl]-4-ethyl-1,2,4-triazole Chemical compound N=1N=C(C=2C(=CC=CC=2)Br)N(CC)C=1SCC1=CC=C(Cl)C(Cl)=C1 WODFFZGITLJNLS-UHFFFAOYSA-N 0.000 claims 1
• NCRIPJHEVGSKLF-UHFFFAOYSA-N 3-(2-bromophenyl)-5-[(3,5-dimethoxyphenyl)methylsulfanyl]-4-ethyl-1,2,4-triazole Chemical compound N=1N=C(C=2C(=CC=CC=2)Br)N(CC)C=1SCC1=CC(OC)=CC(OC)=C1 NCRIPJHEVGSKLF-UHFFFAOYSA-N 0.000 claims 1
• WMLGOGGIJXEBLQ-UHFFFAOYSA-N 3-(2-bromophenyl)-5-[(6-chloro-1,3-benzodioxol-5-yl)methylsulfanyl]-4-ethyl-1,2,4-triazole Chemical compound CCN1C(SCC=2C(=CC=3OCOC=3C=2)Cl)=NN=C1C1=CC=CC=C1Br WMLGOGGIJXEBLQ-UHFFFAOYSA-N 0.000 claims 1
• QEDDHWCZOMHEJN-UHFFFAOYSA-N 3-(2-carbazol-9-ylethyl)-4-(2-methylprop-2-enyl)-1H-1,2,4-triazole-5-thione Chemical compound N1C(=S)N(CC(=C)C)C(CCN2C3=CC=CC=C3C3=CC=CC=C32)=N1 QEDDHWCZOMHEJN-UHFFFAOYSA-N 0.000 claims 1
• SEGJYUDMAPFJDH-UHFFFAOYSA-N 3-(2-carbazol-9-ylethyl)-4-prop-2-enyl-1H-1,2,4-triazole-5-thione Chemical compound N1C(=S)N(CC=C)C(CCN2C3=CC=CC=C3C3=CC=CC=C32)=N1 SEGJYUDMAPFJDH-UHFFFAOYSA-N 0.000 claims 1
• GWQHAEYSRALLID-UHFFFAOYSA-N 3-(2-chlorophenyl)-6,6-dimethyl-5,7-dihydro-1H-[1,2,4]triazolo[4,3-a]pyrimidine Chemical compound N12CC(C)(C)CNC2=NN=C1C1=CC=CC=C1Cl GWQHAEYSRALLID-UHFFFAOYSA-N 0.000 claims 1
• GKWMIVQJQWDXQZ-UHFFFAOYSA-N 3-(2-chlorophenyl)-6,7,8,9-tetrahydro-5H-[1,2,4]triazolo[4,3-a]azepine Chemical compound ClC1=CC=CC=C1C1=NN=C2N1CCCCC2 GKWMIVQJQWDXQZ-UHFFFAOYSA-N 0.000 claims 1
• QINSYGOHQYKFPF-UHFFFAOYSA-N 3-(2-chlorophenyl)-N-cyclohexyl-N-methylprop-2-enamide Chemical compound C=1C=CC=C(Cl)C=1C=CC(=O)N(C)C1CCCCC1 QINSYGOHQYKFPF-UHFFFAOYSA-N 0.000 claims 1
• WIDYZQDJTCZHEP-UHFFFAOYSA-N 3-(2-fluorophenyl)-4-methyl-5-[(4-methylphenyl)methylsulfanyl]-1,2,4-triazole Chemical compound C1=CC(C)=CC=C1CSC(N1C)=NN=C1C1=CC=CC=C1F WIDYZQDJTCZHEP-UHFFFAOYSA-N 0.000 claims 1
• NVFDSULLRHMJQU-UHFFFAOYSA-N 3-(2-fluorophenyl)-5-(4-methoxyphenoxy)-[1,2,4]triazolo[4,3-c]quinazoline Chemical compound C1=CC(OC)=CC=C1OC(N12)=NC3=CC=CC=C3C2=NN=C1C1=CC=CC=C1F NVFDSULLRHMJQU-UHFFFAOYSA-N 0.000 claims 1
• HIEGDBRJAYGLNK-UHFFFAOYSA-N 3-(2-fluorophenyl)-5-[(4-fluorophenyl)methylsulfanyl]-4-methyl-1,2,4-triazole Chemical compound N=1N=C(C=2C(=CC=CC=2)F)N(C)C=1SCC1=CC=C(F)C=C1 HIEGDBRJAYGLNK-UHFFFAOYSA-N 0.000 claims 1
• HGKDAPBOUPXJKC-UHFFFAOYSA-N 3-(2-hydroxyphenyl)-1,3-di(piperidin-1-yl)propan-1-one Chemical compound OC1=CC=CC=C1C(N1CCCCC1)CC(=O)N1CCCCC1 HGKDAPBOUPXJKC-UHFFFAOYSA-N 0.000 claims 1
• DXLSNMWLJNIWCG-UHFFFAOYSA-N 3-(2-methoxyethylsulfanyl)-4-(3-methoxypropyl)-5-thiophen-2-yl-1,2,4-triazole Chemical compound COCCCN1C(SCCOC)=NN=C1C1=CC=CS1 DXLSNMWLJNIWCG-UHFFFAOYSA-N 0.000 claims 1
• NBQVVFPOWJXAKT-UHFFFAOYSA-N 3-(2-methoxyethylsulfanyl)-5-(2-methoxyphenyl)-4-(3-methoxypropyl)-1,2,4-triazole Chemical compound COCCCN1C(SCCOC)=NN=C1C1=CC=CC=C1OC NBQVVFPOWJXAKT-UHFFFAOYSA-N 0.000 claims 1
• AFRGNIDHOWKOTB-UHFFFAOYSA-N 3-(3,4-dichlorophenyl)-6,7,8,9-tetrahydro-5H-[1,2,4]triazolo[4,3-a]azepine Chemical compound C1=C(Cl)C(Cl)=CC=C1C1=NN=C2N1CCCCC2 AFRGNIDHOWKOTB-UHFFFAOYSA-N 0.000 claims 1
• PREGFDQQYHBIGQ-UHFFFAOYSA-N 3-(3,4-dihydro-2H-quinoline-1-carbonyl)-N-phenylbenzenesulfonamide Chemical compound C1CCC2=CC=CC=C2N1C(=O)C(C=1)=CC=CC=1S(=O)(=O)NC1=CC=CC=C1 PREGFDQQYHBIGQ-UHFFFAOYSA-N 0.000 claims 1
• NZYZRDCUROHPJS-UHFFFAOYSA-N 3-(3-bromophenyl)-6,7,8,9-tetrahydro-5H-[1,2,4]triazolo[4,3-a]azepine Chemical compound BrC1=CC=CC(C=2N3CCCCCC3=NN=2)=C1 NZYZRDCUROHPJS-UHFFFAOYSA-N 0.000 claims 1
• DKSBFJYPICUHGY-UHFFFAOYSA-N 3-(3-chloro-4-methylthiophen-2-yl)-4-ethyl-5-[(2-nitrophenyl)methylsulfanyl]-1,2,4-triazole Chemical compound N=1N=C(C2=C(C(C)=CS2)Cl)N(CC)C=1SCC1=CC=CC=C1[N+]([O-])=O DKSBFJYPICUHGY-UHFFFAOYSA-N 0.000 claims 1
• KHOKJXYLHXIULU-UHFFFAOYSA-N 3-(3-chloro-4-methylthiophen-2-yl)-4-ethyl-5-[(3-nitrophenyl)methylsulfanyl]-1,2,4-triazole Chemical compound N=1N=C(C2=C(C(C)=CS2)Cl)N(CC)C=1SCC1=CC=CC([N+]([O-])=O)=C1 KHOKJXYLHXIULU-UHFFFAOYSA-N 0.000 claims 1
• OEAWYODXCQXBKI-UHFFFAOYSA-N 3-(3-chloro-4-methylthiophen-2-yl)-4-ethyl-5-[(4-methylphenyl)methylsulfanyl]-1,2,4-triazole Chemical compound N=1N=C(C2=C(C(C)=CS2)Cl)N(CC)C=1SCC1=CC=C(C)C=C1 OEAWYODXCQXBKI-UHFFFAOYSA-N 0.000 claims 1
• XXZQXUMKRCUIJL-UHFFFAOYSA-N 3-(3-chloro-4-methylthiophen-2-yl)-4-ethyl-5-[(5-methyl-2-nitrophenyl)methylsulfanyl]-1,2,4-triazole Chemical compound N=1N=C(C2=C(C(C)=CS2)Cl)N(CC)C=1SCC1=CC(C)=CC=C1[N+]([O-])=O XXZQXUMKRCUIJL-UHFFFAOYSA-N 0.000 claims 1
• LVQHDRPKPCOZHW-UHFFFAOYSA-N 3-(3-chloro-4-methylthiophen-2-yl)-4-ethyl-5-[[3-(trifluoromethoxy)phenyl]methylsulfanyl]-1,2,4-triazole Chemical compound N=1N=C(C2=C(C(C)=CS2)Cl)N(CC)C=1SCC1=CC=CC(OC(F)(F)F)=C1 LVQHDRPKPCOZHW-UHFFFAOYSA-N 0.000 claims 1
• RGDYXWNGNRWOKY-UHFFFAOYSA-N 3-(3-chloro-4-methylthiophen-2-yl)-4-ethyl-5-[[4-(trifluoromethoxy)phenyl]methylsulfanyl]-1,2,4-triazole Chemical compound N=1N=C(C2=C(C(C)=CS2)Cl)N(CC)C=1SCC1=CC=C(OC(F)(F)F)C=C1 RGDYXWNGNRWOKY-UHFFFAOYSA-N 0.000 claims 1
• NHYZBLDZJVEMDA-UHFFFAOYSA-N 3-(3-chloro-4-methylthiophen-2-yl)-4-ethyl-5-[[4-(trifluoromethyl)phenyl]methylsulfanyl]-1,2,4-triazole Chemical compound N=1N=C(C2=C(C(C)=CS2)Cl)N(CC)C=1SCC1=CC=C(C(F)(F)F)C=C1 NHYZBLDZJVEMDA-UHFFFAOYSA-N 0.000 claims 1
• KNACMFWQZAPIJJ-UHFFFAOYSA-N 3-(3-chloro-4-methylthiophen-2-yl)-5-[(2,6-dichlorophenyl)methylsulfanyl]-4-ethyl-1,2,4-triazole Chemical compound N=1N=C(C2=C(C(C)=CS2)Cl)N(CC)C=1SCC1=C(Cl)C=CC=C1Cl KNACMFWQZAPIJJ-UHFFFAOYSA-N 0.000 claims 1
• DXSYANUFWLNTRO-UHFFFAOYSA-N 3-(3-chloro-4-methylthiophen-2-yl)-5-[(2-chlorophenyl)methylsulfanyl]-4-ethyl-1,2,4-triazole Chemical compound N=1N=C(C2=C(C(C)=CS2)Cl)N(CC)C=1SCC1=CC=CC=C1Cl DXSYANUFWLNTRO-UHFFFAOYSA-N 0.000 claims 1
• SFLBLJRLLAMZIO-UHFFFAOYSA-N 3-(3-chloro-4-methylthiophen-2-yl)-5-[(3,4-dichlorophenyl)methylsulfanyl]-4-ethyl-1,2,4-triazole Chemical compound N=1N=C(C2=C(C(C)=CS2)Cl)N(CC)C=1SCC1=CC=C(Cl)C(Cl)=C1 SFLBLJRLLAMZIO-UHFFFAOYSA-N 0.000 claims 1
• WPVJPFLNVCGFQS-UHFFFAOYSA-N 3-(3-chlorophenyl)-4-prop-2-enyl-1H-1,2,4-triazole-5-thione Chemical compound ClC1=CC=CC(C=2N(C(=S)NN=2)CC=C)=C1 WPVJPFLNVCGFQS-UHFFFAOYSA-N 0.000 claims 1
• DYOWYUZNXBKQOK-UHFFFAOYSA-N 3-(3-chlorophenyl)-6,7,8,9-tetrahydro-5H-[1,2,4]triazolo[4,3-a]azepine Chemical compound ClC1=CC=CC(C=2N3CCCCCC3=NN=2)=C1 DYOWYUZNXBKQOK-UHFFFAOYSA-N 0.000 claims 1
• PUBFRHXTIKNIPW-UHFFFAOYSA-N 3-(3-methyl-2-nitrophenyl)-4-(2-methylprop-2-enyl)-1H-1,2,4-triazole-5-thione Chemical compound N1C(=S)N(CC(=C)C)C(C=2C(=C(C)C=CC=2)[N+]([O-])=O)=N1 PUBFRHXTIKNIPW-UHFFFAOYSA-N 0.000 claims 1
• CSDPTKWMJHKXRS-UHFFFAOYSA-N 3-(3-methylphenyl)-4-(2-methylprop-2-enyl)-1H-1,2,4-triazole-5-thione Chemical compound N1C(=S)N(CC(=C)C)C(C=2C=C(C)C=CC=2)=N1 CSDPTKWMJHKXRS-UHFFFAOYSA-N 0.000 claims 1
• AGGUEVUAPLNPMU-UHFFFAOYSA-N 3-(3-methylphenyl)-4-prop-2-enyl-1H-1,2,4-triazole-5-thione Chemical compound CC1=CC=CC(C=2N(C(=S)NN=2)CC=C)=C1 AGGUEVUAPLNPMU-UHFFFAOYSA-N 0.000 claims 1
• RJTOIWUKIUGUPL-UHFFFAOYSA-N 3-(4-bromophenyl)-4-(2-methylprop-2-enyl)-1H-1,2,4-triazole-5-thione Chemical compound N1C(=S)N(CC(=C)C)C(C=2C=CC(Br)=CC=2)=N1 RJTOIWUKIUGUPL-UHFFFAOYSA-N 0.000 claims 1
• AMYLUVBFQNSLRI-UHFFFAOYSA-N 3-(4-bromophenyl)-5,5-dimethyl-6H-[1,2,4]triazolo[3,4-a]isoquinoline Chemical compound N12C(C)(C)CC3=CC=CC=C3C2=NN=C1C1=CC=C(Br)C=C1 AMYLUVBFQNSLRI-UHFFFAOYSA-N 0.000 claims 1
• ADECVMMOLHCQTO-UHFFFAOYSA-N 3-(4-bromophenyl)-6,7,8,9-tetrahydro-5H-[1,2,4]triazolo[4,3-a]azepine Chemical compound C1=CC(Br)=CC=C1C1=NN=C2N1CCCCC2 ADECVMMOLHCQTO-UHFFFAOYSA-N 0.000 claims 1
• DRIRVGMWCBVYST-UHFFFAOYSA-N 3-(4-chlorophenyl)-4-ethyl-5-[(3-nitrophenyl)methylsulfanyl]-1,2,4-triazole Chemical compound N=1N=C(C=2C=CC(Cl)=CC=2)N(CC)C=1SCC1=CC=CC([N+]([O-])=O)=C1 DRIRVGMWCBVYST-UHFFFAOYSA-N 0.000 claims 1
• JLOLBXBPRLYBSL-UHFFFAOYSA-N 3-(4-chlorophenyl)-4-ethyl-5-[(4-methylphenyl)methylsulfanyl]-1,2,4-triazole Chemical compound N=1N=C(C=2C=CC(Cl)=CC=2)N(CC)C=1SCC1=CC=C(C)C=C1 JLOLBXBPRLYBSL-UHFFFAOYSA-N 0.000 claims 1
• XMFOFLJJASGUFY-UHFFFAOYSA-N 3-(4-chlorophenyl)-4-ethyl-5-[(4-methylsulfonylphenyl)methylsulfanyl]-1,2,4-triazole Chemical compound N=1N=C(C=2C=CC(Cl)=CC=2)N(CC)C=1SCC1=CC=C(S(C)(=O)=O)C=C1 XMFOFLJJASGUFY-UHFFFAOYSA-N 0.000 claims 1
• APYGBEMLYNUVCI-UHFFFAOYSA-N 3-(4-chlorophenyl)-4-ethyl-5-[(4-phenylmethoxyphenyl)methylsulfanyl]-1,2,4-triazole Chemical compound N=1N=C(C=2C=CC(Cl)=CC=2)N(CC)C=1SCC(C=C1)=CC=C1OCC1=CC=CC=C1 APYGBEMLYNUVCI-UHFFFAOYSA-N 0.000 claims 1
• TWCNQHCTOGUTRB-UHFFFAOYSA-N 3-(4-chlorophenyl)-4-ethyl-5-[(5-methyl-2-nitrophenyl)methylsulfanyl]-1,2,4-triazole Chemical compound N=1N=C(C=2C=CC(Cl)=CC=2)N(CC)C=1SCC1=CC(C)=CC=C1[N+]([O-])=O TWCNQHCTOGUTRB-UHFFFAOYSA-N 0.000 claims 1
• AJLJGWCTYZBDQA-UHFFFAOYSA-N 3-(4-chlorophenyl)-4-ethyl-5-[[3-(trifluoromethoxy)phenyl]methylsulfanyl]-1,2,4-triazole Chemical compound N=1N=C(C=2C=CC(Cl)=CC=2)N(CC)C=1SCC1=CC=CC(OC(F)(F)F)=C1 AJLJGWCTYZBDQA-UHFFFAOYSA-N 0.000 claims 1
• PCJFDYFYSAOPMZ-UHFFFAOYSA-N 3-(4-chlorophenyl)-5-[(2,4-dichlorophenyl)methylsulfanyl]-4-ethyl-1,2,4-triazole Chemical compound N=1N=C(C=2C=CC(Cl)=CC=2)N(CC)C=1SCC1=CC=C(Cl)C=C1Cl PCJFDYFYSAOPMZ-UHFFFAOYSA-N 0.000 claims 1
• VYOHRIAPEJXCRD-UHFFFAOYSA-N 3-(4-chlorophenyl)-5-[(2,6-dichlorophenyl)methylsulfanyl]-4-ethyl-1,2,4-triazole Chemical compound N=1N=C(C=2C=CC(Cl)=CC=2)N(CC)C=1SCC1=C(Cl)C=CC=C1Cl VYOHRIAPEJXCRD-UHFFFAOYSA-N 0.000 claims 1
• TULXKOCSNDHOBC-UHFFFAOYSA-N 3-(4-chlorophenyl)-5-[(2-chlorophenyl)methylsulfanyl]-4-ethyl-1,2,4-triazole Chemical compound N=1N=C(C=2C=CC(Cl)=CC=2)N(CC)C=1SCC1=CC=CC=C1Cl TULXKOCSNDHOBC-UHFFFAOYSA-N 0.000 claims 1
• ACPDCMHBCLKTOE-UHFFFAOYSA-N 3-(4-chlorophenyl)-5-[(3,4-dichlorophenyl)methylsulfanyl]-4-ethyl-1,2,4-triazole Chemical compound N=1N=C(C=2C=CC(Cl)=CC=2)N(CC)C=1SCC1=CC=C(Cl)C(Cl)=C1 ACPDCMHBCLKTOE-UHFFFAOYSA-N 0.000 claims 1
• PHGMTQJBXXFRJO-UHFFFAOYSA-N 3-(4-chlorophenyl)-6,7,8,9-tetrahydro-5H-[1,2,4]triazolo[4,3-a]azepine Chemical compound C1=CC(Cl)=CC=C1C1=NN=C2N1CCCCC2 PHGMTQJBXXFRJO-UHFFFAOYSA-N 0.000 claims 1
• HZHSTMOFYQBVPV-UHFFFAOYSA-N 3-(4-fluorophenyl)-1-(4-phenylpiperidin-1-yl)but-2-en-1-one Chemical compound C=1C=C(F)C=CC=1C(C)=CC(=O)N(CC1)CCC1C1=CC=CC=C1 HZHSTMOFYQBVPV-UHFFFAOYSA-N 0.000 claims 1
• WYBSOKBHOSUTJC-UHFFFAOYSA-N 3-(4-methoxyphenyl)-4-(2-methylprop-2-enyl)-1H-1,2,4-triazole-5-thione Chemical compound C1=CC(OC)=CC=C1C1=NNC(=S)N1CC(C)=C WYBSOKBHOSUTJC-UHFFFAOYSA-N 0.000 claims 1
• LUGLLAHZGTUSAE-UHFFFAOYSA-N 3-(4-methoxyphenyl)-5,5,8,9-tetramethyl-6H-[1,2,4]triazolo[3,4-a]isoquinoline Chemical compound C1=CC(OC)=CC=C1C1=NN=C2N1C(C)(C)CC1=CC(C)=C(C)C=C12 LUGLLAHZGTUSAE-UHFFFAOYSA-N 0.000 claims 1
• KXLBDDZCWXWYRL-UHFFFAOYSA-N 3-(4-methoxyphenyl)-6,7,8,9-tetrahydro-5H-[1,2,4]triazolo[4,3-a]azepine Chemical compound C1=CC(OC)=CC=C1C1=NN=C2N1CCCCC2 KXLBDDZCWXWYRL-UHFFFAOYSA-N 0.000 claims 1
• MDGGRHZKMXXZRD-UHFFFAOYSA-N 3-(4-methylphenyl)-6,7,8,9-tetrahydro-5H-[1,2,4]triazolo[4,3-a]azepine Chemical compound C1=CC(C)=CC=C1C1=NN=C2N1CCCCC2 MDGGRHZKMXXZRD-UHFFFAOYSA-N 0.000 claims 1
• FTYKJOBQOANJJP-UHFFFAOYSA-N 3-(4-methylphenyl)-N-propan-2-yladamantane-1-carboxamide Chemical compound C1C(C(=O)NC(C)C)(C2)CC(C3)CC1CC32C1=CC=C(C)C=C1 FTYKJOBQOANJJP-UHFFFAOYSA-N 0.000 claims 1
• MVXLFZJXAAYQJJ-UHFFFAOYSA-N 3-(4-tert-butylphenyl)-5-[(2,6-dichlorophenyl)methylsulfanyl]-4-(furan-2-ylmethyl)-1,2,4-triazole Chemical compound C1=CC(C(C)(C)C)=CC=C1C(N1CC=2OC=CC=2)=NN=C1SCC1=C(Cl)C=CC=C1Cl MVXLFZJXAAYQJJ-UHFFFAOYSA-N 0.000 claims 1
• OUNBBIYHRZELDA-UHFFFAOYSA-N 3-(5,5-dimethyl-6H-[1,2,4]triazolo[3,4-a]isoquinolin-3-yl)phenol Chemical compound N12C(C)(C)CC3=CC=CC=C3C2=NN=C1C1=CC=CC(O)=C1 OUNBBIYHRZELDA-UHFFFAOYSA-N 0.000 claims 1
• YGTVDHWYOZPHMY-UHFFFAOYSA-N 3-(5-benzylsulfanyl-4-ethyl-1,2,4-triazol-3-yl)-2-methylsulfanylpyridine Chemical compound N=1N=C(C=2C(=NC=CC=2)SC)N(CC)C=1SCC1=CC=CC=C1 YGTVDHWYOZPHMY-UHFFFAOYSA-N 0.000 claims 1
• FBXOKRBDIYUJGM-UHFFFAOYSA-N 3-(5-benzylsulfanyl-4-ethyl-1,2,4-triazol-3-yl)propan-1-ol Chemical compound CCN1C(CCCO)=NN=C1SCC1=CC=CC=C1 FBXOKRBDIYUJGM-UHFFFAOYSA-N 0.000 claims 1
• VPHVTDGUKROOHL-UHFFFAOYSA-N 3-(5-benzylsulfanyl-4-ethyl-1,2,4-triazol-3-yl)pyridine Chemical compound N=1N=C(C=2C=NC=CC=2)N(CC)C=1SCC1=CC=CC=C1 VPHVTDGUKROOHL-UHFFFAOYSA-N 0.000 claims 1
• OBSJSIGVRWBCFL-UHFFFAOYSA-N 3-(5-benzylsulfanyl-4-methyl-1,2,4-triazol-3-yl)-2,7-dimethylimidazo[1,2-a]pyridine Chemical compound CC=1N=C2C=C(C)C=CN2C=1C(N1C)=NN=C1SCC1=CC=CC=C1 OBSJSIGVRWBCFL-UHFFFAOYSA-N 0.000 claims 1
• HJNOSFFVUAXXSY-UHFFFAOYSA-N 3-(5-benzylsulfanyl-4-methyl-1,2,4-triazol-3-yl)-2-methylimidazo[1,2-a]pyridine Chemical compound CC=1N=C2C=CC=CN2C=1C(N1C)=NN=C1SCC1=CC=CC=C1 HJNOSFFVUAXXSY-UHFFFAOYSA-N 0.000 claims 1
• MMSKOIQDXOUXSX-UHFFFAOYSA-N 3-(5-bromopyridin-3-yl)-6,7,8,9-tetrahydro-5H-[1,2,4]triazolo[4,3-a]azepine Chemical compound BrC1=CN=CC(C=2N3CCCCCC3=NN=2)=C1 MMSKOIQDXOUXSX-UHFFFAOYSA-N 0.000 claims 1
• YYCWXPFBQDRXTH-UHFFFAOYSA-N 3-(5-chlorothiophen-2-yl)-4-ethyl-5-[(2-nitrophenyl)methylsulfanyl]-1,2,4-triazole Chemical compound N=1N=C(C=2SC(Cl)=CC=2)N(CC)C=1SCC1=CC=CC=C1[N+]([O-])=O YYCWXPFBQDRXTH-UHFFFAOYSA-N 0.000 claims 1
• QBVWFWOUVGMAJC-UHFFFAOYSA-N 3-(5-chlorothiophen-2-yl)-4-ethyl-5-[(3-nitrophenyl)methylsulfanyl]-1,2,4-triazole Chemical compound N=1N=C(C=2SC(Cl)=CC=2)N(CC)C=1SCC1=CC=CC([N+]([O-])=O)=C1 QBVWFWOUVGMAJC-UHFFFAOYSA-N 0.000 claims 1
• CGKMIYPWIDPIEW-UHFFFAOYSA-N 3-(5-chlorothiophen-2-yl)-4-ethyl-5-[(4-methoxyphenyl)methylsulfanyl]-1,2,4-triazole Chemical compound N=1N=C(C=2SC(Cl)=CC=2)N(CC)C=1SCC1=CC=C(OC)C=C1 CGKMIYPWIDPIEW-UHFFFAOYSA-N 0.000 claims 1
• SRBQTOUPIGSLSD-UHFFFAOYSA-N 3-(5-chlorothiophen-2-yl)-4-ethyl-5-[(4-methylphenyl)methylsulfanyl]-1,2,4-triazole Chemical compound N=1N=C(C=2SC(Cl)=CC=2)N(CC)C=1SCC1=CC=C(C)C=C1 SRBQTOUPIGSLSD-UHFFFAOYSA-N 0.000 claims 1
• JUMDBOWTNBNBAH-UHFFFAOYSA-N 3-(5-chlorothiophen-2-yl)-4-ethyl-5-[(5-methyl-2-nitrophenyl)methylsulfanyl]-1,2,4-triazole Chemical compound N=1N=C(C=2SC(Cl)=CC=2)N(CC)C=1SCC1=CC(C)=CC=C1[N+]([O-])=O JUMDBOWTNBNBAH-UHFFFAOYSA-N 0.000 claims 1
• AGWZHLWCSRPPHL-UHFFFAOYSA-N 3-(5-chlorothiophen-2-yl)-4-ethyl-5-[[3-(trifluoromethoxy)phenyl]methylsulfanyl]-1,2,4-triazole Chemical compound N=1N=C(C=2SC(Cl)=CC=2)N(CC)C=1SCC1=CC=CC(OC(F)(F)F)=C1 AGWZHLWCSRPPHL-UHFFFAOYSA-N 0.000 claims 1
• KGEWKEKOCXUMHB-UHFFFAOYSA-N 3-(5-chlorothiophen-2-yl)-4-ethyl-5-[[4-(trifluoromethoxy)phenyl]methylsulfanyl]-1,2,4-triazole Chemical compound N=1N=C(C=2SC(Cl)=CC=2)N(CC)C=1SCC1=CC=C(OC(F)(F)F)C=C1 KGEWKEKOCXUMHB-UHFFFAOYSA-N 0.000 claims 1
• QJNOKMXOENBCAV-UHFFFAOYSA-N 3-(5-chlorothiophen-2-yl)-4-ethyl-5-[[4-(trifluoromethyl)phenyl]methylsulfanyl]-1,2,4-triazole Chemical compound N=1N=C(C=2SC(Cl)=CC=2)N(CC)C=1SCC1=CC=C(C(F)(F)F)C=C1 QJNOKMXOENBCAV-UHFFFAOYSA-N 0.000 claims 1
• DSTDGDBENPWUKI-UHFFFAOYSA-N 3-(5-chlorothiophen-2-yl)-5-(cyclohexylmethylsulfanyl)-4-ethyl-1,2,4-triazole Chemical compound N=1N=C(C=2SC(Cl)=CC=2)N(CC)C=1SCC1CCCCC1 DSTDGDBENPWUKI-UHFFFAOYSA-N 0.000 claims 1
• DEGHVHJRDUXQTB-UHFFFAOYSA-N 3-(5-chlorothiophen-2-yl)-5-[(2,4-dichlorophenyl)methylsulfanyl]-4-ethyl-1,2,4-triazole Chemical compound N=1N=C(C=2SC(Cl)=CC=2)N(CC)C=1SCC1=CC=C(Cl)C=C1Cl DEGHVHJRDUXQTB-UHFFFAOYSA-N 0.000 claims 1
• MQNCKDQKNKRLCB-UHFFFAOYSA-N 3-(5-chlorothiophen-2-yl)-5-[(2,6-dichlorophenyl)methylsulfanyl]-4-ethyl-1,2,4-triazole Chemical compound N=1N=C(C=2SC(Cl)=CC=2)N(CC)C=1SCC1=C(Cl)C=CC=C1Cl MQNCKDQKNKRLCB-UHFFFAOYSA-N 0.000 claims 1
• OHAXZCWWCMVISL-UHFFFAOYSA-N 3-(5-chlorothiophen-2-yl)-5-[(3,4-dichlorophenyl)methylsulfanyl]-4-ethyl-1,2,4-triazole Chemical compound N=1N=C(C=2SC(Cl)=CC=2)N(CC)C=1SCC1=CC=C(Cl)C(Cl)=C1 OHAXZCWWCMVISL-UHFFFAOYSA-N 0.000 claims 1
• IZFUWGQEROOAMA-UHFFFAOYSA-N 3-(5-chlorothiophen-2-yl)-5-[(3,5-dimethoxyphenyl)methylsulfanyl]-4-ethyl-1,2,4-triazole Chemical compound N=1N=C(C=2SC(Cl)=CC=2)N(CC)C=1SCC1=CC(OC)=CC(OC)=C1 IZFUWGQEROOAMA-UHFFFAOYSA-N 0.000 claims 1
• UDKDUWDCNBRCHZ-UHFFFAOYSA-N 3-(5-hex-1-ynylpyridin-3-yl)-6,7,8,9-tetrahydro-5H-[1,2,4]triazolo[4,3-a]azepine Chemical compound CCCCC#CC1=CN=CC(C=2N3CCCCCC3=NN=2)=C1 UDKDUWDCNBRCHZ-UHFFFAOYSA-N 0.000 claims 1
• JWZIWHICRPFTPD-UHFFFAOYSA-N 3-(6-chloropyridin-2-yl)oxy-N-ethylbenzamide Chemical compound CCNC(=O)C1=CC=CC(OC=2N=C(Cl)C=CC=2)=C1 JWZIWHICRPFTPD-UHFFFAOYSA-N 0.000 claims 1
• VJQYEVURLUHRTB-UHFFFAOYSA-N 3-(6-chloropyridin-3-yl)-6,7,8,9-tetrahydro-5H-[1,2,4]triazolo[4,3-a]azepine Chemical compound C1=NC(Cl)=CC=C1C1=NN=C2N1CCCCC2 VJQYEVURLUHRTB-UHFFFAOYSA-N 0.000 claims 1
• MODAQROJTGKNOV-UHFFFAOYSA-N 3-(cyclohexylmethylsulfanyl)-4-ethyl-5-(4-methoxyphenyl)-1,2,4-triazole Chemical compound N=1N=C(C=2C=CC(OC)=CC=2)N(CC)C=1SCC1CCCCC1 MODAQROJTGKNOV-UHFFFAOYSA-N 0.000 claims 1
• HWFNQYPSZMBXGY-UHFFFAOYSA-N 3-(cyclohexylmethylsulfanyl)-4-ethyl-5-(5-methylthiophen-2-yl)-1,2,4-triazole Chemical compound N=1N=C(C=2SC(C)=CC=2)N(CC)C=1SCC1CCCCC1 HWFNQYPSZMBXGY-UHFFFAOYSA-N 0.000 claims 1
• AGFZJQDWVBDHHF-UHFFFAOYSA-N 3-(furan-2-yl)-5,5,8,9-tetramethyl-6H-[1,2,4]triazolo[3,4-a]isoquinoline Chemical compound N=1N=C2C=3C=C(C)C(C)=CC=3CC(C)(C)N2C=1C1=CC=CO1 AGFZJQDWVBDHHF-UHFFFAOYSA-N 0.000 claims 1
• SQTDQYVVYDFZBN-UHFFFAOYSA-N 3-(furan-2-yl)-5,5-dimethyl-6H-[1,2,4]triazolo[3,4-a]isoquinoline Chemical compound N12C(C)(C)CC3=CC=CC=C3C2=NN=C1C1=CC=CO1 SQTDQYVVYDFZBN-UHFFFAOYSA-N 0.000 claims 1
• BGFVNQHINQLFDX-UHFFFAOYSA-N 3-[(2,4-dichlorophenyl)methylsulfanyl]-4-ethyl-5-(2-phenoxyphenyl)-1,2,4-triazole Chemical compound N=1N=C(C=2C(=CC=CC=2)OC=2C=CC=CC=2)N(CC)C=1SCC1=CC=C(Cl)C=C1Cl BGFVNQHINQLFDX-UHFFFAOYSA-N 0.000 claims 1
• QERQFZYFMJSMCA-UHFFFAOYSA-N 3-[(2,4-dichlorophenyl)methylsulfanyl]-4-ethyl-5-(5-methylthiophen-2-yl)-1,2,4-triazole Chemical compound N=1N=C(C=2SC(C)=CC=2)N(CC)C=1SCC1=CC=C(Cl)C=C1Cl QERQFZYFMJSMCA-UHFFFAOYSA-N 0.000 claims 1
• UJIVCZXZMNVCFR-UHFFFAOYSA-N 3-[(2,4-dichlorophenyl)methylsulfanyl]-4-ethyl-5-[1-phenyl-5-(trifluoromethyl)pyrazol-4-yl]-1,2,4-triazole Chemical compound N=1N=C(C2=C(N(N=C2)C=2C=CC=CC=2)C(F)(F)F)N(CC)C=1SCC1=CC=C(Cl)C=C1Cl UJIVCZXZMNVCFR-UHFFFAOYSA-N 0.000 claims 1
• AJDRZYDXIDTOCN-UHFFFAOYSA-N 3-[(2,4-dichlorophenyl)methylsulfanyl]-4-ethyl-5-naphthalen-1-yl-1,2,4-triazole Chemical compound N=1N=C(C=2C3=CC=CC=C3C=CC=2)N(CC)C=1SCC1=CC=C(Cl)C=C1Cl AJDRZYDXIDTOCN-UHFFFAOYSA-N 0.000 claims 1
• SAKNPYKNUYWQRS-UHFFFAOYSA-N 3-[(2,4-dichlorophenyl)methylsulfanyl]-5-[4-(2,5-dimethylpyrrol-1-yl)phenyl]-4-ethyl-1,2,4-triazole Chemical compound N=1N=C(C=2C=CC(=CC=2)N2C(=CC=C2C)C)N(CC)C=1SCC1=CC=C(Cl)C=C1Cl SAKNPYKNUYWQRS-UHFFFAOYSA-N 0.000 claims 1
• LOJGCWANQZFGFB-UHFFFAOYSA-N 3-[(2,6-dichlorophenyl)methylsulfanyl]-4-ethyl-5-(2-methoxyphenyl)-1,2,4-triazole Chemical compound N=1N=C(C=2C(=CC=CC=2)OC)N(CC)C=1SCC1=C(Cl)C=CC=C1Cl LOJGCWANQZFGFB-UHFFFAOYSA-N 0.000 claims 1
• OEKRFTKYTLFADR-UHFFFAOYSA-N 3-[(2,6-dichlorophenyl)methylsulfanyl]-4-ethyl-5-(2-phenoxyphenyl)-1,2,4-triazole Chemical compound N=1N=C(C=2C(=CC=CC=2)OC=2C=CC=CC=2)N(CC)C=1SCC1=C(Cl)C=CC=C1Cl OEKRFTKYTLFADR-UHFFFAOYSA-N 0.000 claims 1
• YZXXYFLKJPWWHU-UHFFFAOYSA-N 3-[(2,6-dichlorophenyl)methylsulfanyl]-4-ethyl-5-(4-methoxyphenyl)-1,2,4-triazole Chemical compound N=1N=C(C=2C=CC(OC)=CC=2)N(CC)C=1SCC1=C(Cl)C=CC=C1Cl YZXXYFLKJPWWHU-UHFFFAOYSA-N 0.000 claims 1
• DITBEPNZCZFQCA-UHFFFAOYSA-N 3-[(2,6-dichlorophenyl)methylsulfanyl]-4-ethyl-5-(5-methylthiophen-2-yl)-1,2,4-triazole Chemical compound N=1N=C(C=2SC(C)=CC=2)N(CC)C=1SCC1=C(Cl)C=CC=C1Cl DITBEPNZCZFQCA-UHFFFAOYSA-N 0.000 claims 1
• XXZRCWAGJZZABV-UHFFFAOYSA-N 3-[(2,6-dichlorophenyl)methylsulfanyl]-4-ethyl-5-[1-phenyl-5-(trifluoromethyl)pyrazol-4-yl]-1,2,4-triazole Chemical compound N=1N=C(C2=C(N(N=C2)C=2C=CC=CC=2)C(F)(F)F)N(CC)C=1SCC1=C(Cl)C=CC=C1Cl XXZRCWAGJZZABV-UHFFFAOYSA-N 0.000 claims 1
• SVIHRIYPMJSUGY-UHFFFAOYSA-N 3-[(2,6-dichlorophenyl)methylsulfanyl]-4-ethyl-5-naphthalen-1-yl-1,2,4-triazole Chemical compound N=1N=C(C=2C3=CC=CC=C3C=CC=2)N(CC)C=1SCC1=C(Cl)C=CC=C1Cl SVIHRIYPMJSUGY-UHFFFAOYSA-N 0.000 claims 1
• XBBJHCGKPFKHTM-UHFFFAOYSA-N 3-[(2,6-dichlorophenyl)methylsulfanyl]-4-ethyl-5-thiophen-2-yl-1,2,4-triazole Chemical compound N=1N=C(C=2SC=CC=2)N(CC)C=1SCC1=C(Cl)C=CC=C1Cl XBBJHCGKPFKHTM-UHFFFAOYSA-N 0.000 claims 1
• IDKORPCVVKPQDI-UHFFFAOYSA-N 3-[(2-bromophenyl)methylsulfanyl]-4-methyl-5-(4-nitrophenyl)-1,2,4-triazole Chemical compound N=1N=C(C=2C=CC(=CC=2)[N+]([O-])=O)N(C)C=1SCC1=CC=CC=C1Br IDKORPCVVKPQDI-UHFFFAOYSA-N 0.000 claims 1
• IRYHRUBBGYXNIL-UHFFFAOYSA-N 3-[(2-chlorophenyl)methylsulfanyl]-4-ethyl-5-(2-methoxyphenyl)-1,2,4-triazole Chemical compound N=1N=C(C=2C(=CC=CC=2)OC)N(CC)C=1SCC1=CC=CC=C1Cl IRYHRUBBGYXNIL-UHFFFAOYSA-N 0.000 claims 1
• COORSKCUQTXUFA-UHFFFAOYSA-N 3-[(2-chlorophenyl)methylsulfanyl]-4-ethyl-5-(5-methylthiophen-2-yl)-1,2,4-triazole Chemical compound N=1N=C(C=2SC(C)=CC=2)N(CC)C=1SCC1=CC=CC=C1Cl COORSKCUQTXUFA-UHFFFAOYSA-N 0.000 claims 1
• GAUAYWJNBPTGLG-UHFFFAOYSA-N 3-[(2-chlorophenyl)methylsulfanyl]-4-ethyl-5-[1-phenyl-5-(trifluoromethyl)pyrazol-4-yl]-1,2,4-triazole Chemical compound N=1N=C(C2=C(N(N=C2)C=2C=CC=CC=2)C(F)(F)F)N(CC)C=1SCC1=CC=CC=C1Cl GAUAYWJNBPTGLG-UHFFFAOYSA-N 0.000 claims 1
• ZSICKQQNKZOXBJ-UHFFFAOYSA-N 3-[(3,4-dichlorophenyl)methylsulfanyl]-4-ethyl-5-(2-phenoxyphenyl)-1,2,4-triazole Chemical compound N=1N=C(C=2C(=CC=CC=2)OC=2C=CC=CC=2)N(CC)C=1SCC1=CC=C(Cl)C(Cl)=C1 ZSICKQQNKZOXBJ-UHFFFAOYSA-N 0.000 claims 1
• LUOKHYJDRWQRRY-UHFFFAOYSA-N 3-[(3,4-dichlorophenyl)methylsulfanyl]-4-ethyl-5-(4-methoxyphenyl)-1,2,4-triazole Chemical compound N=1N=C(C=2C=CC(OC)=CC=2)N(CC)C=1SCC1=CC=C(Cl)C(Cl)=C1 LUOKHYJDRWQRRY-UHFFFAOYSA-N 0.000 claims 1
• AQXZWGFZOLXGNA-UHFFFAOYSA-N 3-[(3,4-dichlorophenyl)methylsulfanyl]-4-ethyl-5-(5-methylthiophen-2-yl)-1,2,4-triazole Chemical compound N=1N=C(C=2SC(C)=CC=2)N(CC)C=1SCC1=CC=C(Cl)C(Cl)=C1 AQXZWGFZOLXGNA-UHFFFAOYSA-N 0.000 claims 1
• XKSAONHUJOUUDX-UHFFFAOYSA-N 3-[(3,4-dichlorophenyl)methylsulfanyl]-4-ethyl-5-thiophen-2-yl-1,2,4-triazole Chemical compound N=1N=C(C=2SC=CC=2)N(CC)C=1SCC1=CC=C(Cl)C(Cl)=C1 XKSAONHUJOUUDX-UHFFFAOYSA-N 0.000 claims 1
• IHDCPKXRIKICLN-UHFFFAOYSA-N 3-[(3,4-dichlorophenyl)methylsulfanyl]-5-[4-(2,5-dimethylpyrrol-1-yl)phenyl]-4-ethyl-1,2,4-triazole Chemical compound N=1N=C(C=2C=CC(=CC=2)N2C(=CC=C2C)C)N(CC)C=1SCC1=CC=C(Cl)C(Cl)=C1 IHDCPKXRIKICLN-UHFFFAOYSA-N 0.000 claims 1
• ZJSXIHSBVFDSER-UHFFFAOYSA-N 3-[(3,5-dimethoxyphenyl)methylsulfanyl]-4-ethyl-5-(2-methoxyphenyl)-1,2,4-triazole Chemical compound N=1N=C(C=2C(=CC=CC=2)OC)N(CC)C=1SCC1=CC(OC)=CC(OC)=C1 ZJSXIHSBVFDSER-UHFFFAOYSA-N 0.000 claims 1
• PMKANHCXMHJNHL-UHFFFAOYSA-N 3-[(3,5-dimethoxyphenyl)methylsulfanyl]-4-ethyl-5-(2-phenoxyphenyl)-1,2,4-triazole Chemical compound N=1N=C(C=2C(=CC=CC=2)OC=2C=CC=CC=2)N(CC)C=1SCC1=CC(OC)=CC(OC)=C1 PMKANHCXMHJNHL-UHFFFAOYSA-N 0.000 claims 1
• ODWAPLZHNWQTNS-UHFFFAOYSA-N 3-[(3,5-dimethoxyphenyl)methylsulfanyl]-4-ethyl-5-(5-methylthiophen-2-yl)-1,2,4-triazole Chemical compound N=1N=C(C=2SC(C)=CC=2)N(CC)C=1SCC1=CC(OC)=CC(OC)=C1 ODWAPLZHNWQTNS-UHFFFAOYSA-N 0.000 claims 1
• KMZZIBWYKJTLCK-UHFFFAOYSA-N 3-[(3,5-dimethoxyphenyl)methylsulfanyl]-4-ethyl-5-[1-phenyl-5-(trifluoromethyl)pyrazol-4-yl]-1,2,4-triazole Chemical compound N=1N=C(C2=C(N(N=C2)C=2C=CC=CC=2)C(F)(F)F)N(CC)C=1SCC1=CC(OC)=CC(OC)=C1 KMZZIBWYKJTLCK-UHFFFAOYSA-N 0.000 claims 1
• MYUAHKWKJFPTEA-UHFFFAOYSA-N 3-[(3,5-dimethoxyphenyl)methylsulfanyl]-4-ethyl-5-thiophen-2-yl-1,2,4-triazole Chemical compound N=1N=C(C=2SC=CC=2)N(CC)C=1SCC1=CC(OC)=CC(OC)=C1 MYUAHKWKJFPTEA-UHFFFAOYSA-N 0.000 claims 1
• FEJSQOZDTHOEPJ-UHFFFAOYSA-N 3-[(3,5-dimethoxyphenyl)methylsulfanyl]-5-[4-(2,5-dimethylpyrrol-1-yl)phenyl]-4-ethyl-1,2,4-triazole Chemical compound N=1N=C(C=2C=CC(=CC=2)N2C(=CC=C2C)C)N(CC)C=1SCC1=CC(OC)=CC(OC)=C1 FEJSQOZDTHOEPJ-UHFFFAOYSA-N 0.000 claims 1
• FLUACYKOEXGOCO-UHFFFAOYSA-N 3-[(3-methoxyphenyl)methylsulfanyl]-4-methyl-5-thiophen-2-yl-1,2,4-triazole Chemical compound COC1=CC=CC(CSC=2N(C(C=3SC=CC=3)=NN=2)C)=C1 FLUACYKOEXGOCO-UHFFFAOYSA-N 0.000 claims 1
• WZFWCZCJXWJYTD-UHFFFAOYSA-N 3-[(4-bromophenyl)methylsulfanyl]-4-ethyl-5-(2-phenoxyphenyl)-1,2,4-triazole Chemical compound N=1N=C(C=2C(=CC=CC=2)OC=2C=CC=CC=2)N(CC)C=1SCC1=CC=C(Br)C=C1 WZFWCZCJXWJYTD-UHFFFAOYSA-N 0.000 claims 1
• IOKZATWVPBLTGG-UHFFFAOYSA-N 3-[(4-bromophenyl)methylsulfanyl]-4-ethyl-5-(4-methoxyphenyl)-1,2,4-triazole Chemical compound N=1N=C(C=2C=CC(OC)=CC=2)N(CC)C=1SCC1=CC=C(Br)C=C1 IOKZATWVPBLTGG-UHFFFAOYSA-N 0.000 claims 1
• TVUKXMVXBQEEDL-UHFFFAOYSA-N 3-[(4-bromophenyl)methylsulfanyl]-4-ethyl-5-thiophen-2-yl-1,2,4-triazole Chemical compound N=1N=C(C=2SC=CC=2)N(CC)C=1SCC1=CC=C(Br)C=C1 TVUKXMVXBQEEDL-UHFFFAOYSA-N 0.000 claims 1
• HGEFRRPCYFAVNP-UHFFFAOYSA-N 3-[(4-bromophenyl)methylsulfanyl]-5-(5-chlorothiophen-2-yl)-4-ethyl-1,2,4-triazole Chemical compound N=1N=C(C=2SC(Cl)=CC=2)N(CC)C=1SCC1=CC=C(Br)C=C1 HGEFRRPCYFAVNP-UHFFFAOYSA-N 0.000 claims 1
• XWQFBDANJFMJGA-UHFFFAOYSA-N 3-[(4-chlorophenyl)methylsulfanyl]-4-ethyl-5-(4-nitrophenyl)-1,2,4-triazole Chemical compound N=1N=C(C=2C=CC(=CC=2)[N+]([O-])=O)N(CC)C=1SCC1=CC=C(Cl)C=C1 XWQFBDANJFMJGA-UHFFFAOYSA-N 0.000 claims 1
• PTBOVXACVWXRBG-UHFFFAOYSA-N 3-[(4-fluorophenyl)methylsulfanyl]-4-methyl-5-thiophen-2-yl-1,2,4-triazole Chemical compound N=1N=C(C=2SC=CC=2)N(C)C=1SCC1=CC=C(F)C=C1 PTBOVXACVWXRBG-UHFFFAOYSA-N 0.000 claims 1
• NPABVKBKBFUMHA-UHFFFAOYSA-N 3-[(4-methoxyphenyl)methylsulfanyl]-4-methyl-5-phenyl-1,2,4-triazole Chemical compound C1=CC(OC)=CC=C1CSC(N1C)=NN=C1C1=CC=CC=C1 NPABVKBKBFUMHA-UHFFFAOYSA-N 0.000 claims 1
• LBBOQIQYPQBDHO-UHFFFAOYSA-N 3-[(4-tert-butylphenyl)methylsulfanyl]-4-methyl-5-thiophen-2-yl-1,2,4-triazole Chemical compound N=1N=C(C=2SC=CC=2)N(C)C=1SCC1=CC=C(C(C)(C)C)C=C1 LBBOQIQYPQBDHO-UHFFFAOYSA-N 0.000 claims 1
• CJZFSHKTPZNMBF-UHFFFAOYSA-N 3-[(6-chloro-1,3-benzodioxol-5-yl)methylsulfanyl]-4-ethyl-5-(2-methoxyphenyl)-1,2,4-triazole Chemical compound CCN1C(SCC=2C(=CC=3OCOC=3C=2)Cl)=NN=C1C1=CC=CC=C1OC CJZFSHKTPZNMBF-UHFFFAOYSA-N 0.000 claims 1
• CWBMMSLNAYLRPT-UHFFFAOYSA-N 3-[(6-chloro-1,3-benzodioxol-5-yl)methylsulfanyl]-4-ethyl-5-(2-phenoxyphenyl)-1,2,4-triazole Chemical compound CCN1C(SCC=2C(=CC=3OCOC=3C=2)Cl)=NN=C1C1=CC=CC=C1OC1=CC=CC=C1 CWBMMSLNAYLRPT-UHFFFAOYSA-N 0.000 claims 1
• NJRAIMZHLZAZJT-UHFFFAOYSA-N 3-[(6-chloro-1,3-benzodioxol-5-yl)methylsulfanyl]-4-ethyl-5-(4-methoxyphenyl)-1,2,4-triazole Chemical compound CCN1C(SCC=2C(=CC=3OCOC=3C=2)Cl)=NN=C1C1=CC=C(OC)C=C1 NJRAIMZHLZAZJT-UHFFFAOYSA-N 0.000 claims 1
• SFQFCEXIVZTHGU-UHFFFAOYSA-N 3-[(6-chloro-1,3-benzodioxol-5-yl)methylsulfanyl]-4-ethyl-5-(5-methylthiophen-2-yl)-1,2,4-triazole Chemical compound CCN1C(SCC=2C(=CC=3OCOC=3C=2)Cl)=NN=C1C1=CC=C(C)S1 SFQFCEXIVZTHGU-UHFFFAOYSA-N 0.000 claims 1
• UDPBMSXXHPBWDF-UHFFFAOYSA-N 3-[(6-chloro-1,3-benzodioxol-5-yl)methylsulfanyl]-4-ethyl-5-[1-phenyl-5-(trifluoromethyl)pyrazol-4-yl]-1,2,4-triazole Chemical compound CCN1C(SCC=2C(=CC=3OCOC=3C=2)Cl)=NN=C1C(=C1C(F)(F)F)C=NN1C1=CC=CC=C1 UDPBMSXXHPBWDF-UHFFFAOYSA-N 0.000 claims 1
• CUIUQAMNEKABRY-UHFFFAOYSA-N 3-[(6-chloro-1,3-benzodioxol-5-yl)methylsulfanyl]-4-ethyl-5-thiophen-2-yl-1,2,4-triazole Chemical compound CCN1C(SCC=2C(=CC=3OCOC=3C=2)Cl)=NN=C1C1=CC=CS1 CUIUQAMNEKABRY-UHFFFAOYSA-N 0.000 claims 1
• KVFIPBBQJARLOV-UHFFFAOYSA-N 3-[(6-chloro-1,3-benzodioxol-5-yl)methylsulfanyl]-5-[4-(2,5-dimethylpyrrol-1-yl)phenyl]-4-ethyl-1,2,4-triazole Chemical compound CCN1C(SCC=2C(=CC=3OCOC=3C=2)Cl)=NN=C1C(C=C1)=CC=C1N1C(C)=CC=C1C KVFIPBBQJARLOV-UHFFFAOYSA-N 0.000 claims 1
• AESWMSCLVNNIQD-UHFFFAOYSA-N 3-[1-(1H-indole-5-carbonyl)piperidin-4-yl]-1H-benzimidazol-2-one Chemical compound C1=C2NC=CC2=CC(C(N2CCC(CC2)N2C(NC3=CC=CC=C32)=O)=O)=C1 AESWMSCLVNNIQD-UHFFFAOYSA-N 0.000 claims 1
• RAWVSRAIUPFWKY-UHFFFAOYSA-N 3-[1-(3-cyclohexylpropanoyl)piperidin-4-yl]-1H-benzimidazol-2-one Chemical compound C1CC(N2C(NC3=CC=CC=C32)=O)CCN1C(=O)CCC1CCCCC1 RAWVSRAIUPFWKY-UHFFFAOYSA-N 0.000 claims 1
• VIXSEPGMXMZCNJ-UHFFFAOYSA-N 3-[1-(6-phenylhexanoyl)piperidin-4-yl]-1H-benzimidazol-2-one Chemical compound C1CC(N2C(NC3=CC=CC=C32)=O)CCN1C(=O)CCCCCC1=CC=CC=C1 VIXSEPGMXMZCNJ-UHFFFAOYSA-N 0.000 claims 1
• KYKSBULMCOJGHZ-UHFFFAOYSA-N 3-[2-(1,3-dioxoisoindol-2-yl)ethyl]adamantane-1-carboxylic acid Chemical compound O=C1C2=CC=CC=C2C(=O)N1CCC1(C2)CC(C3)CC2CC3(C(=O)O)C1 KYKSBULMCOJGHZ-UHFFFAOYSA-N 0.000 claims 1
• CKHBZLXXKPRRNV-UHFFFAOYSA-N 3-[3-(4-ethoxyphenyl)-7-methylpyrazolo[1,5-a]pyrimidin-2-yl]piperidine-1-carbaldehyde Chemical compound C1=CC(OCC)=CC=C1C1=C2N=CC=C(C)N2N=C1C1CN(C=O)CCC1 CKHBZLXXKPRRNV-UHFFFAOYSA-N 0.000 claims 1
• UJJSZCSLQQMCEA-UHFFFAOYSA-N 3-[3-[(2,4-dichlorophenyl)methoxy]thiophen-2-yl]-4-methyl-1H-1,2,4-triazole-5-thione Chemical compound N1C(=S)N(C)C(C2=C(C=CS2)OCC=2C(=CC(Cl)=CC=2)Cl)=N1 UJJSZCSLQQMCEA-UHFFFAOYSA-N 0.000 claims 1
• FWYLPZHZJQXRCC-UHFFFAOYSA-N 3-[3-[(2,4-dichlorophenyl)methoxy]thiophen-2-yl]-4-methyl-5-methylsulfanyl-1,2,4-triazole Chemical compound CN1C(SC)=NN=C1C1=C(OCC=2C(=CC(Cl)=CC=2)Cl)C=CS1 FWYLPZHZJQXRCC-UHFFFAOYSA-N 0.000 claims 1
• OMGQRBXCEOHLIC-UHFFFAOYSA-N 3-[4-(2,3-dimethylphenyl)piperazine-1-carbonyl]isochromen-1-one Chemical compound CC1=CC=CC(N2CCN(CC2)C(=O)C=2OC(=O)C3=CC=CC=C3C=2)=C1C OMGQRBXCEOHLIC-UHFFFAOYSA-N 0.000 claims 1
• WUKSKSMKGWHRNF-UHFFFAOYSA-N 3-[4-(2,5-dimethylpyrrol-1-yl)phenyl]-4-ethyl-5-[(2-nitrophenyl)methylsulfanyl]-1,2,4-triazole Chemical compound N=1N=C(C=2C=CC(=CC=2)N2C(=CC=C2C)C)N(CC)C=1SCC1=CC=CC=C1[N+]([O-])=O WUKSKSMKGWHRNF-UHFFFAOYSA-N 0.000 claims 1
• RDMZQNGHMYNXHB-UHFFFAOYSA-N 3-[4-(2,5-dimethylpyrrol-1-yl)phenyl]-4-ethyl-5-[(3-nitrophenyl)methylsulfanyl]-1,2,4-triazole Chemical compound N=1N=C(C=2C=CC(=CC=2)N2C(=CC=C2C)C)N(CC)C=1SCC1=CC=CC([N+]([O-])=O)=C1 RDMZQNGHMYNXHB-UHFFFAOYSA-N 0.000 claims 1
• FGBONUAUMBDMJP-UHFFFAOYSA-N 3-[4-(2,5-dimethylpyrrol-1-yl)phenyl]-4-ethyl-5-[(4-methoxyphenyl)methylsulfanyl]-1,2,4-triazole Chemical compound N=1N=C(C=2C=CC(=CC=2)N2C(=CC=C2C)C)N(CC)C=1SCC1=CC=C(OC)C=C1 FGBONUAUMBDMJP-UHFFFAOYSA-N 0.000 claims 1
• RYPBPPUWFCBFPP-UHFFFAOYSA-N 3-[4-(2,5-dimethylpyrrol-1-yl)phenyl]-4-ethyl-5-[(4-methylsulfonylphenyl)methylsulfanyl]-1,2,4-triazole Chemical compound N=1N=C(C=2C=CC(=CC=2)N2C(=CC=C2C)C)N(CC)C=1SCC1=CC=C(S(C)(=O)=O)C=C1 RYPBPPUWFCBFPP-UHFFFAOYSA-N 0.000 claims 1
• YEBXQSPQBBWMHD-UHFFFAOYSA-N 3-[4-(2,5-dimethylpyrrol-1-yl)phenyl]-4-ethyl-5-[(4-nitrophenyl)methylsulfanyl]-1,2,4-triazole Chemical compound N=1N=C(C=2C=CC(=CC=2)N2C(=CC=C2C)C)N(CC)C=1SCC1=CC=C([N+]([O-])=O)C=C1 YEBXQSPQBBWMHD-UHFFFAOYSA-N 0.000 claims 1
• UWYQWHLJKVMZSS-UHFFFAOYSA-N 3-[4-(2,5-dimethylpyrrol-1-yl)phenyl]-4-ethyl-5-[(4-phenylmethoxyphenyl)methylsulfanyl]-1,2,4-triazole Chemical compound N=1N=C(C=2C=CC(=CC=2)N2C(=CC=C2C)C)N(CC)C=1SCC(C=C1)=CC=C1OCC1=CC=CC=C1 UWYQWHLJKVMZSS-UHFFFAOYSA-N 0.000 claims 1
• HNJLAXQOGWIJNY-UHFFFAOYSA-N 3-[4-(2,5-dimethylpyrrol-1-yl)phenyl]-4-ethyl-5-[(5-methyl-2-nitrophenyl)methylsulfanyl]-1,2,4-triazole Chemical compound N=1N=C(C=2C=CC(=CC=2)N2C(=CC=C2C)C)N(CC)C=1SCC1=CC(C)=CC=C1[N+]([O-])=O HNJLAXQOGWIJNY-UHFFFAOYSA-N 0.000 claims 1
• UZYKFACDGDQGID-UHFFFAOYSA-N 3-[4-(2,5-dimethylpyrrol-1-yl)phenyl]-4-ethyl-5-[[4-(trifluoromethoxy)phenyl]methylsulfanyl]-1,2,4-triazole Chemical compound N=1N=C(C=2C=CC(=CC=2)N2C(=CC=C2C)C)N(CC)C=1SCC1=CC=C(OC(F)(F)F)C=C1 UZYKFACDGDQGID-UHFFFAOYSA-N 0.000 claims 1
• IQZQPIQRXJBMNP-UHFFFAOYSA-N 3-[4-(2,5-dimethylpyrrol-1-yl)phenyl]-4-ethyl-5-[[4-(trifluoromethyl)phenyl]methylsulfanyl]-1,2,4-triazole Chemical compound N=1N=C(C=2C=CC(=CC=2)N2C(=CC=C2C)C)N(CC)C=1SCC1=CC=C(C(F)(F)F)C=C1 IQZQPIQRXJBMNP-UHFFFAOYSA-N 0.000 claims 1
• KYQYKLYWKGVGAP-UHFFFAOYSA-N 3-[4-(2-ethoxyphenyl)piperazine-1-carbonyl]isochromen-1-one Chemical compound CCOC1=CC=CC=C1N1CCN(C(=O)C=2OC(=O)C3=CC=CC=C3C=2)CC1 KYQYKLYWKGVGAP-UHFFFAOYSA-N 0.000 claims 1
• JPKCHGNOMVKVFU-UHFFFAOYSA-N 3-[4-ethyl-5-[(2-nitrophenyl)methylsulfanyl]-1,2,4-triazol-3-yl]-2-methylsulfanylpyridine Chemical compound N=1N=C(C=2C(=NC=CC=2)SC)N(CC)C=1SCC1=CC=CC=C1[N+]([O-])=O JPKCHGNOMVKVFU-UHFFFAOYSA-N 0.000 claims 1
• AXLZXXSFCOIMNB-UHFFFAOYSA-N 3-[4-ethyl-5-[(2-nitrophenyl)methylsulfanyl]-1,2,4-triazol-3-yl]propan-1-ol Chemical compound CCN1C(CCCO)=NN=C1SCC1=CC=CC=C1[N+]([O-])=O AXLZXXSFCOIMNB-UHFFFAOYSA-N 0.000 claims 1
• FCLJMOCSQSZVBA-UHFFFAOYSA-N 3-[4-ethyl-5-[(2-nitrophenyl)methylsulfanyl]-1,2,4-triazol-3-yl]pyridine Chemical compound N=1N=C(C=2C=NC=CC=2)N(CC)C=1SCC1=CC=CC=C1[N+]([O-])=O FCLJMOCSQSZVBA-UHFFFAOYSA-N 0.000 claims 1
• NMXDDCIDHCFWOV-UHFFFAOYSA-N 3-[4-ethyl-5-[(3-nitrophenyl)methylsulfanyl]-1,2,4-triazol-3-yl]propan-1-ol Chemical compound CCN1C(CCCO)=NN=C1SCC1=CC=CC([N+]([O-])=O)=C1 NMXDDCIDHCFWOV-UHFFFAOYSA-N 0.000 claims 1
• RKSOGEXMQNGICA-UHFFFAOYSA-N 3-[4-ethyl-5-[(3-nitrophenyl)methylsulfanyl]-1,2,4-triazol-3-yl]pyridine Chemical compound N=1N=C(C=2C=NC=CC=2)N(CC)C=1SCC1=CC=CC([N+]([O-])=O)=C1 RKSOGEXMQNGICA-UHFFFAOYSA-N 0.000 claims 1
• UPHYKYARZIXRIB-UHFFFAOYSA-N 3-[4-ethyl-5-[(4-methoxyphenyl)methylsulfanyl]-1,2,4-triazol-3-yl]pyridine Chemical compound N=1N=C(C=2C=NC=CC=2)N(CC)C=1SCC1=CC=C(OC)C=C1 UPHYKYARZIXRIB-UHFFFAOYSA-N 0.000 claims 1
• HXZYKKYLHOJMQK-UHFFFAOYSA-N 3-[4-ethyl-5-[(4-methylphenyl)methylsulfanyl]-1,2,4-triazol-3-yl]-2-methylsulfanylpyridine Chemical compound N=1N=C(C=2C(=NC=CC=2)SC)N(CC)C=1SCC1=CC=C(C)C=C1 HXZYKKYLHOJMQK-UHFFFAOYSA-N 0.000 claims 1
• HXNVXTNSOQDIAV-UHFFFAOYSA-N 3-[4-ethyl-5-[(4-methylphenyl)methylsulfanyl]-1,2,4-triazol-3-yl]pyridine Chemical compound N=1N=C(C=2C=NC=CC=2)N(CC)C=1SCC1=CC=C(C)C=C1 HXNVXTNSOQDIAV-UHFFFAOYSA-N 0.000 claims 1
• DABBXGIEQXBRBS-UHFFFAOYSA-N 3-[4-ethyl-5-[(4-methylsulfonylphenyl)methylsulfanyl]-1,2,4-triazol-3-yl]-2-methylsulfanylpyridine Chemical compound N=1N=C(C=2C(=NC=CC=2)SC)N(CC)C=1SCC1=CC=C(S(C)(=O)=O)C=C1 DABBXGIEQXBRBS-UHFFFAOYSA-N 0.000 claims 1
• NLABIGWVHQVUNX-UHFFFAOYSA-N 3-[4-ethyl-5-[(4-methylsulfonylphenyl)methylsulfanyl]-1,2,4-triazol-3-yl]propan-1-ol Chemical compound CCN1C(CCCO)=NN=C1SCC1=CC=C(S(C)(=O)=O)C=C1 NLABIGWVHQVUNX-UHFFFAOYSA-N 0.000 claims 1
• BLXHHWJLQHRCRE-UHFFFAOYSA-N 3-[4-ethyl-5-[(4-methylsulfonylphenyl)methylsulfanyl]-1,2,4-triazol-3-yl]pyridine Chemical compound N=1N=C(C=2C=NC=CC=2)N(CC)C=1SCC1=CC=C(S(C)(=O)=O)C=C1 BLXHHWJLQHRCRE-UHFFFAOYSA-N 0.000 claims 1
• QOOSBVXUMBBSIM-UHFFFAOYSA-N 3-[4-ethyl-5-[(4-phenylmethoxyphenyl)methylsulfanyl]-1,2,4-triazol-3-yl]-2-methylsulfanylpyridine Chemical compound N=1N=C(C=2C(=NC=CC=2)SC)N(CC)C=1SCC(C=C1)=CC=C1OCC1=CC=CC=C1 QOOSBVXUMBBSIM-UHFFFAOYSA-N 0.000 claims 1
• JPMQUJRZAOCXCM-UHFFFAOYSA-N 3-[4-ethyl-5-[(4-phenylmethoxyphenyl)methylsulfanyl]-1,2,4-triazol-3-yl]pyridine Chemical compound N=1N=C(C=2C=NC=CC=2)N(CC)C=1SCC(C=C1)=CC=C1OCC1=CC=CC=C1 JPMQUJRZAOCXCM-UHFFFAOYSA-N 0.000 claims 1
• KBHMOSDOPCSSSJ-UHFFFAOYSA-N 3-[4-ethyl-5-[(5-methyl-2-nitrophenyl)methylsulfanyl]-1,2,4-triazol-3-yl]-2-methylsulfanylpyridine Chemical compound N=1N=C(C=2C(=NC=CC=2)SC)N(CC)C=1SCC1=CC(C)=CC=C1[N+]([O-])=O KBHMOSDOPCSSSJ-UHFFFAOYSA-N 0.000 claims 1
• XNEUNIPTDIKTHX-UHFFFAOYSA-N 3-[4-ethyl-5-[(5-methyl-2-nitrophenyl)methylsulfanyl]-1,2,4-triazol-3-yl]propan-1-ol Chemical compound CCN1C(CCCO)=NN=C1SCC1=CC(C)=CC=C1[N+]([O-])=O XNEUNIPTDIKTHX-UHFFFAOYSA-N 0.000 claims 1
• DKXLSAPVUXSUPS-UHFFFAOYSA-N 3-[4-ethyl-5-[(5-methyl-2-nitrophenyl)methylsulfanyl]-1,2,4-triazol-3-yl]pyridine Chemical compound N=1N=C(C=2C=NC=CC=2)N(CC)C=1SCC1=CC(C)=CC=C1[N+]([O-])=O DKXLSAPVUXSUPS-UHFFFAOYSA-N 0.000 claims 1
• PWTPVTAMRQRLLE-UHFFFAOYSA-N 3-[4-ethyl-5-[[3-(trifluoromethoxy)phenyl]methylsulfanyl]-1,2,4-triazol-3-yl]-2-methylsulfanylpyridine Chemical compound N=1N=C(C=2C(=NC=CC=2)SC)N(CC)C=1SCC1=CC=CC(OC(F)(F)F)=C1 PWTPVTAMRQRLLE-UHFFFAOYSA-N 0.000 claims 1
• MUUMKPOBYXXBQQ-UHFFFAOYSA-N 3-[4-ethyl-5-[[3-(trifluoromethoxy)phenyl]methylsulfanyl]-1,2,4-triazol-3-yl]propan-1-ol Chemical compound CCN1C(CCCO)=NN=C1SCC1=CC=CC(OC(F)(F)F)=C1 MUUMKPOBYXXBQQ-UHFFFAOYSA-N 0.000 claims 1
• INXKOPLFUHPDKT-UHFFFAOYSA-N 3-[4-ethyl-5-[[3-(trifluoromethoxy)phenyl]methylsulfanyl]-1,2,4-triazol-3-yl]pyridine Chemical compound N=1N=C(C=2C=NC=CC=2)N(CC)C=1SCC1=CC=CC(OC(F)(F)F)=C1 INXKOPLFUHPDKT-UHFFFAOYSA-N 0.000 claims 1
• LIQKCJGUBVDPRD-UHFFFAOYSA-N 3-[4-ethyl-5-[[4-(trifluoromethoxy)phenyl]methylsulfanyl]-1,2,4-triazol-3-yl]-2-methylsulfanylpyridine Chemical compound N=1N=C(C=2C(=NC=CC=2)SC)N(CC)C=1SCC1=CC=C(OC(F)(F)F)C=C1 LIQKCJGUBVDPRD-UHFFFAOYSA-N 0.000 claims 1
• SRNOJCSARXWTAT-UHFFFAOYSA-N 3-[4-ethyl-5-[[4-(trifluoromethoxy)phenyl]methylsulfanyl]-1,2,4-triazol-3-yl]pyridine Chemical compound N=1N=C(C=2C=NC=CC=2)N(CC)C=1SCC1=CC=C(OC(F)(F)F)C=C1 SRNOJCSARXWTAT-UHFFFAOYSA-N 0.000 claims 1
• JXHVHSWQECWVRF-UHFFFAOYSA-N 3-[4-ethyl-5-[[4-(trifluoromethyl)phenyl]methylsulfanyl]-1,2,4-triazol-3-yl]-2-methylsulfanylpyridine Chemical compound N=1N=C(C=2C(=NC=CC=2)SC)N(CC)C=1SCC1=CC=C(C(F)(F)F)C=C1 JXHVHSWQECWVRF-UHFFFAOYSA-N 0.000 claims 1
• NNFOYWRVDVJJKX-UHFFFAOYSA-N 3-[4-ethyl-5-[[4-(trifluoromethyl)phenyl]methylsulfanyl]-1,2,4-triazol-3-yl]propan-1-ol Chemical compound CCN1C(CCCO)=NN=C1SCC1=CC=C(C(F)(F)F)C=C1 NNFOYWRVDVJJKX-UHFFFAOYSA-N 0.000 claims 1
• LTPRKFGJHMENLP-UHFFFAOYSA-N 3-[4-ethyl-5-[[4-(trifluoromethyl)phenyl]methylsulfanyl]-1,2,4-triazol-3-yl]pyridine Chemical compound N=1N=C(C=2C=NC=CC=2)N(CC)C=1SCC1=CC=C(C(F)(F)F)C=C1 LTPRKFGJHMENLP-UHFFFAOYSA-N 0.000 claims 1
• QIKVBFQXZWBRFQ-UHFFFAOYSA-N 3-[5-(cyclohexylmethylsulfanyl)-4-ethyl-1,2,4-triazol-3-yl]-2-methylsulfanylpyridine Chemical compound N=1N=C(C=2C(=NC=CC=2)SC)N(CC)C=1SCC1CCCCC1 QIKVBFQXZWBRFQ-UHFFFAOYSA-N 0.000 claims 1
• PGZCWMRBISUIIZ-UHFFFAOYSA-N 3-[5-(cyclohexylmethylsulfanyl)-4-ethyl-1,2,4-triazol-3-yl]propan-1-ol Chemical compound CCN1C(CCCO)=NN=C1SCC1CCCCC1 PGZCWMRBISUIIZ-UHFFFAOYSA-N 0.000 claims 1
• RNFVTUFEPVBIQP-UHFFFAOYSA-N 3-[5-[(2,4-dichlorophenyl)methylsulfanyl]-4-ethyl-1,2,4-triazol-3-yl]pyridine Chemical compound N=1N=C(C=2C=NC=CC=2)N(CC)C=1SCC1=CC=C(Cl)C=C1Cl RNFVTUFEPVBIQP-UHFFFAOYSA-N 0.000 claims 1
• SFGLOWGRYQQGLR-UHFFFAOYSA-N 3-[5-[(2,4-dichlorophenyl)methylsulfanyl]-4-methyl-1,2,4-triazol-3-yl]-2,8-dimethylimidazo[1,2-a]pyridine Chemical compound CC=1N=C2C(C)=CC=CN2C=1C(N1C)=NN=C1SCC1=CC=C(Cl)C=C1Cl SFGLOWGRYQQGLR-UHFFFAOYSA-N 0.000 claims 1
• RAXDJEDVIWAWJP-UHFFFAOYSA-N 3-[5-[(2,4-dichlorophenyl)methylsulfanyl]-4-methyl-1,2,4-triazol-3-yl]pyridine Chemical compound N=1N=C(C=2C=NC=CC=2)N(C)C=1SCC1=CC=C(Cl)C=C1Cl RAXDJEDVIWAWJP-UHFFFAOYSA-N 0.000 claims 1
• BPGDCBSWZVKJOA-UHFFFAOYSA-N 3-[5-[(2,6-dichlorophenyl)methylsulfanyl]-4-ethyl-1,2,4-triazol-3-yl]-2-methylsulfanylpyridine Chemical compound N=1N=C(C=2C(=NC=CC=2)SC)N(CC)C=1SCC1=C(Cl)C=CC=C1Cl BPGDCBSWZVKJOA-UHFFFAOYSA-N 0.000 claims 1
• NYPCKFBNUJIGCD-UHFFFAOYSA-N 3-[5-[(2,6-dichlorophenyl)methylsulfanyl]-4-ethyl-1,2,4-triazol-3-yl]propan-1-ol Chemical compound CCN1C(CCCO)=NN=C1SCC1=C(Cl)C=CC=C1Cl NYPCKFBNUJIGCD-UHFFFAOYSA-N 0.000 claims 1
• MOELOLORCAQMQB-UHFFFAOYSA-N 3-[5-[(2,6-dichlorophenyl)methylsulfanyl]-4-ethyl-1,2,4-triazol-3-yl]pyridine Chemical compound N=1N=C(C=2C=NC=CC=2)N(CC)C=1SCC1=C(Cl)C=CC=C1Cl MOELOLORCAQMQB-UHFFFAOYSA-N 0.000 claims 1
• ZUDRZNYQBNGXPM-UHFFFAOYSA-N 3-[5-[(2-chlorophenyl)methylsulfanyl]-4-ethyl-1,2,4-triazol-3-yl]propan-1-ol Chemical compound CCN1C(CCCO)=NN=C1SCC1=CC=CC=C1Cl ZUDRZNYQBNGXPM-UHFFFAOYSA-N 0.000 claims 1
• YCRQXBFFTSUFSD-UHFFFAOYSA-N 3-[5-[(2-chlorophenyl)methylsulfanyl]-4-ethyl-1,2,4-triazol-3-yl]pyridine Chemical compound N=1N=C(C=2C=NC=CC=2)N(CC)C=1SCC1=CC=CC=C1Cl YCRQXBFFTSUFSD-UHFFFAOYSA-N 0.000 claims 1
• ZTFNZLSGIUNRPY-UHFFFAOYSA-N 3-[5-[(3,4-dichlorophenyl)methylsulfanyl]-4-ethyl-1,2,4-triazol-3-yl]-2-methylsulfanylpyridine Chemical compound N=1N=C(C=2C(=NC=CC=2)SC)N(CC)C=1SCC1=CC=C(Cl)C(Cl)=C1 ZTFNZLSGIUNRPY-UHFFFAOYSA-N 0.000 claims 1
• DPBJNGLWHONYCE-UHFFFAOYSA-N 3-[5-[(3,4-dichlorophenyl)methylsulfanyl]-4-ethyl-1,2,4-triazol-3-yl]propan-1-ol Chemical compound CCN1C(CCCO)=NN=C1SCC1=CC=C(Cl)C(Cl)=C1 DPBJNGLWHONYCE-UHFFFAOYSA-N 0.000 claims 1
• LASUOURWKYTOJW-UHFFFAOYSA-N 3-[5-[(3,4-dichlorophenyl)methylsulfanyl]-4-ethyl-1,2,4-triazol-3-yl]pyridine Chemical compound N=1N=C(C=2C=NC=CC=2)N(CC)C=1SCC1=CC=C(Cl)C(Cl)=C1 LASUOURWKYTOJW-UHFFFAOYSA-N 0.000 claims 1
• MHSYANCLYJRZTL-UHFFFAOYSA-N 3-[5-[(3,5-dimethoxyphenyl)methylsulfanyl]-4-ethyl-1,2,4-triazol-3-yl]-2-methylsulfanylpyridine Chemical compound N=1N=C(C=2C(=NC=CC=2)SC)N(CC)C=1SCC1=CC(OC)=CC(OC)=C1 MHSYANCLYJRZTL-UHFFFAOYSA-N 0.000 claims 1
• KLDKEMLPJDQPJH-UHFFFAOYSA-N 3-[5-[(3,5-dimethoxyphenyl)methylsulfanyl]-4-ethyl-1,2,4-triazol-3-yl]pyridine Chemical compound N=1N=C(C=2C=NC=CC=2)N(CC)C=1SCC1=CC(OC)=CC(OC)=C1 KLDKEMLPJDQPJH-UHFFFAOYSA-N 0.000 claims 1
• KNMXXBFVHJMKDN-UHFFFAOYSA-N 3-[5-[(4-bromophenyl)methylsulfanyl]-4-ethyl-1,2,4-triazol-3-yl]pyridine Chemical compound N=1N=C(C=2C=NC=CC=2)N(CC)C=1SCC1=CC=C(Br)C=C1 KNMXXBFVHJMKDN-UHFFFAOYSA-N 0.000 claims 1
• XKXAJDFJLYIQJB-UHFFFAOYSA-N 3-[5-[(4-chlorophenyl)methylsulfanyl]-4-methyl-1,2,4-triazol-3-yl]-2-methylimidazo[1,2-a]pyridine Chemical compound CC=1N=C2C=CC=CN2C=1C(N1C)=NN=C1SCC1=CC=C(Cl)C=C1 XKXAJDFJLYIQJB-UHFFFAOYSA-N 0.000 claims 1
• HMCIWMFYUATCTC-UHFFFAOYSA-N 3-[5-[(6-chloro-1,3-benzodioxol-5-yl)methylsulfanyl]-4-ethyl-1,2,4-triazol-3-yl]propan-1-ol Chemical compound CCN1C(CCCO)=NN=C1SCC(C(=C1)Cl)=CC2=C1OCO2 HMCIWMFYUATCTC-UHFFFAOYSA-N 0.000 claims 1
• SPZCCCZYZKOXPB-UHFFFAOYSA-N 3-[5-[(6-chloro-1,3-benzodioxol-5-yl)methylsulfanyl]-4-ethyl-1,2,4-triazol-3-yl]pyridine Chemical compound CCN1C(SCC=2C(=CC=3OCOC=3C=2)Cl)=NN=C1C1=CC=CN=C1 SPZCCCZYZKOXPB-UHFFFAOYSA-N 0.000 claims 1
• IIOLFLLTNUCVFD-UHFFFAOYSA-N 3-[5-benzylsulfanyl-4-(2-phenylethyl)-1,2,4-triazol-3-yl]pyridine Chemical compound C=1C=CC=CC=1CCN(C(=NN=1)C=2C=NC=CC=2)C=1SCC1=CC=CC=C1 IIOLFLLTNUCVFD-UHFFFAOYSA-N 0.000 claims 1
• KANGNMIFFURMPC-UHFFFAOYSA-N 3-[[(2-amino-2-oxoethyl)-[3-methoxy-5-(pyridine-2-carbonyl)benzoyl]amino]methyl]benzoic acid Chemical compound C=1C(OC)=CC(C(=O)N(CC(N)=O)CC=2C=C(C=CC=2)C(O)=O)=CC=1C(=O)C1=CC=CC=N1 KANGNMIFFURMPC-UHFFFAOYSA-N 0.000 claims 1
• NJHXKVRXNBUPLG-UHFFFAOYSA-N 3-[[3-imidazol-1-ylpropyl-[3-methoxy-5-(pyridine-2-carbonyl)benzoyl]amino]methyl]benzoic acid Chemical compound C=1C(OC)=CC(C(=O)N(CCCN2C=NC=C2)CC=2C=C(C=CC=2)C(O)=O)=CC=1C(=O)C1=CC=CC=N1 NJHXKVRXNBUPLG-UHFFFAOYSA-N 0.000 claims 1
• OEEOQHRWDRRUFD-UHFFFAOYSA-N 3-[[4-ethyl-5-[(2-nitrophenyl)methylsulfanyl]-1,2,4-triazol-3-yl]methyl]-1H-indole Chemical compound CCN1C(CC=2C3=CC=CC=C3NC=2)=NN=C1SCC1=CC=CC=C1[N+]([O-])=O OEEOQHRWDRRUFD-UHFFFAOYSA-N 0.000 claims 1
• WDXRSQOCSNDAAG-UHFFFAOYSA-N 3-[[4-ethyl-5-[(3-nitrophenyl)methylsulfanyl]-1,2,4-triazol-3-yl]methyl]-1H-indole Chemical compound CCN1C(CC=2C3=CC=CC=C3NC=2)=NN=C1SCC1=CC=CC([N+]([O-])=O)=C1 WDXRSQOCSNDAAG-UHFFFAOYSA-N 0.000 claims 1
• PWUOMGRMJCGQDL-UHFFFAOYSA-N 3-[[4-ethyl-5-[(4-methoxyphenyl)methylsulfanyl]-1,2,4-triazol-3-yl]methyl]-1H-indole Chemical compound CCN1C(CC=2C3=CC=CC=C3NC=2)=NN=C1SCC1=CC=C(OC)C=C1 PWUOMGRMJCGQDL-UHFFFAOYSA-N 0.000 claims 1
• YYIKXVRFVIHXGM-UHFFFAOYSA-N 3-[[4-ethyl-5-[(4-methylsulfonylphenyl)methylsulfanyl]-1,2,4-triazol-3-yl]methyl]-1H-indole Chemical compound CCN1C(CC=2C3=CC=CC=C3NC=2)=NN=C1SCC1=CC=C(S(C)(=O)=O)C=C1 YYIKXVRFVIHXGM-UHFFFAOYSA-N 0.000 claims 1
• IOVHAPVHRXPUIX-UHFFFAOYSA-N 3-[[4-ethyl-5-[(4-nitrophenyl)methylsulfanyl]-1,2,4-triazol-3-yl]methyl]-1H-indole Chemical compound CCN1C(CC=2C3=CC=CC=C3NC=2)=NN=C1SCC1=CC=C([N+]([O-])=O)C=C1 IOVHAPVHRXPUIX-UHFFFAOYSA-N 0.000 claims 1
• ZGPUQSLZCVSYOW-UHFFFAOYSA-N 3-[[4-ethyl-5-[(4-phenylmethoxyphenyl)methylsulfanyl]-1,2,4-triazol-3-yl]methyl]-1H-indole Chemical compound CCN1C(CC=2C3=CC=CC=C3NC=2)=NN=C1SCC(C=C1)=CC=C1OCC1=CC=CC=C1 ZGPUQSLZCVSYOW-UHFFFAOYSA-N 0.000 claims 1
• RTRZIKHCPVUJRO-UHFFFAOYSA-N 3-[[4-ethyl-5-[(5-methyl-2-nitrophenyl)methylsulfanyl]-1,2,4-triazol-3-yl]methyl]-1H-indole Chemical compound CCN1C(CC=2C3=CC=CC=C3NC=2)=NN=C1SCC1=CC(C)=CC=C1[N+]([O-])=O RTRZIKHCPVUJRO-UHFFFAOYSA-N 0.000 claims 1
• KXLMJGGWGIGLQZ-UHFFFAOYSA-N 3-[[4-ethyl-5-[[3-(trifluoromethoxy)phenyl]methylsulfanyl]-1,2,4-triazol-3-yl]methyl]-1H-indole Chemical compound CCN1C(CC=2C3=CC=CC=C3NC=2)=NN=C1SCC1=CC=CC(OC(F)(F)F)=C1 KXLMJGGWGIGLQZ-UHFFFAOYSA-N 0.000 claims 1
• QPGIJIRGLAVNSV-UHFFFAOYSA-N 3-[[5-(3,3,5-trimethyl-7-azabicyclo[3.2.1]octane-7-carbonyl)-1H-indole-3-carbonyl]amino]propanoic acid Chemical compound C1=C2NC=C(C(=O)NCCC(O)=O)C2=CC(C(=O)N2C3CC(CC(C)(C)C3)(C2)C)=C1 QPGIJIRGLAVNSV-UHFFFAOYSA-N 0.000 claims 1
• XMZOCSCCWOIESM-UHFFFAOYSA-N 3-[[5-[(2,4-dichlorophenyl)methylsulfanyl]-4-ethyl-1,2,4-triazol-3-yl]methyl]-1H-indole Chemical compound CCN1C(CC=2C3=CC=CC=C3NC=2)=NN=C1SCC1=CC=C(Cl)C=C1Cl XMZOCSCCWOIESM-UHFFFAOYSA-N 0.000 claims 1
• JWAKVDYLOYTRAI-UHFFFAOYSA-N 3-[[5-[(2,6-dichlorophenyl)methylsulfanyl]-4-ethyl-1,2,4-triazol-3-yl]methyl]-1H-indole Chemical compound CCN1C(CC=2C3=CC=CC=C3NC=2)=NN=C1SCC1=C(Cl)C=CC=C1Cl JWAKVDYLOYTRAI-UHFFFAOYSA-N 0.000 claims 1
• IYQNQRHORBZDKL-UHFFFAOYSA-N 3-[[5-[(3,4-dichlorophenyl)methylsulfanyl]-4-ethyl-1,2,4-triazol-3-yl]methyl]-1H-indole Chemical compound CCN1C(CC=2C3=CC=CC=C3NC=2)=NN=C1SCC1=CC=C(Cl)C(Cl)=C1 IYQNQRHORBZDKL-UHFFFAOYSA-N 0.000 claims 1
• LAFGXKLOHXWNCS-UHFFFAOYSA-N 3-[[5-[(3,5-dimethoxyphenyl)methylsulfanyl]-4-ethyl-1,2,4-triazol-3-yl]methyl]-1H-indole Chemical compound CCN1C(CC=2C3=CC=CC=C3NC=2)=NN=C1SCC1=CC(OC)=CC(OC)=C1 LAFGXKLOHXWNCS-UHFFFAOYSA-N 0.000 claims 1
• QSSZFEXITQOVAN-UHFFFAOYSA-N 3-amino-N-cyclohexyl-N-methylbenzamide Chemical compound C=1C=CC(N)=CC=1C(=O)N(C)C1CCCCC1 QSSZFEXITQOVAN-UHFFFAOYSA-N 0.000 claims 1
• DFDCVQAGGAQLPM-UHFFFAOYSA-N 3-azabicyclo[3.2.2]nonan-3-yl(1H-imidazol-5-yl)methanone Chemical compound C1C(CC2)CCC2CN1C(=O)C1=CNC=N1 DFDCVQAGGAQLPM-UHFFFAOYSA-N 0.000 claims 1
• OMWOJLYJWCJZBS-UHFFFAOYSA-N 3-azabicyclo[3.2.2]nonan-3-yl(1H-indol-3-yl)methanone Chemical compound C1CC(C2)CCC1CN2C(=O)C1=CNC2=CC=CC=C12 OMWOJLYJWCJZBS-UHFFFAOYSA-N 0.000 claims 1
• CRQKCCXRMKLINA-UHFFFAOYSA-N 3-azabicyclo[3.2.2]nonan-3-yl(1H-indol-5-yl)methanone Chemical compound C1CC(C2)CCC1CN2C(=O)C1=CC=C(NC=C2)C2=C1 CRQKCCXRMKLINA-UHFFFAOYSA-N 0.000 claims 1
• UEOPWQUBKNHVMA-UHFFFAOYSA-N 3-azabicyclo[3.2.2]nonan-3-yl(quinolin-2-yl)methanone Chemical compound C1CC(C2)CCC1CN2C(=O)C1=CC=C(C=CC=C2)C2=N1 UEOPWQUBKNHVMA-UHFFFAOYSA-N 0.000 claims 1
• DNLQVIGADVTFPN-UHFFFAOYSA-N 3-azabicyclo[3.2.2]nonan-3-yl-(1-methylindol-3-yl)methanone Chemical compound C1CC(C2)CCC1CN2C(=O)C1=CN(C)C2=CC=CC=C21 DNLQVIGADVTFPN-UHFFFAOYSA-N 0.000 claims 1
• PFGGHCQDRUHGQF-UHFFFAOYSA-N 3-azabicyclo[3.2.2]nonan-3-yl-(2,4-dimethyl-1,3-thiazol-5-yl)methanone Chemical compound S1C(C)=NC(C)=C1C(=O)N1CC(CC2)CCC2C1 PFGGHCQDRUHGQF-UHFFFAOYSA-N 0.000 claims 1
• NXOVBRAJXCOONU-UHFFFAOYSA-N 3-azabicyclo[3.2.2]nonan-3-yl-(2-bromophenyl)methanone Chemical compound BrC1=CC=CC=C1C(=O)N1CC(CC2)CCC2C1 NXOVBRAJXCOONU-UHFFFAOYSA-N 0.000 claims 1
• NTLUMMHVTHLTLV-UHFFFAOYSA-N 3-azabicyclo[3.2.2]nonan-3-yl-(4-methyl-2-phenyl-1,3-thiazol-5-yl)methanone Chemical compound S1C(C(=O)N2CC3CCC(CC3)C2)=C(C)N=C1C1=CC=CC=C1 NTLUMMHVTHLTLV-UHFFFAOYSA-N 0.000 claims 1
• IOUVKGGHRRTOHA-UHFFFAOYSA-N 3-benzyl-4-ethyl-5-[(2-nitrophenyl)methylsulfanyl]-1,2,4-triazole Chemical compound N=1N=C(SCC=2C(=CC=CC=2)[N+]([O-])=O)N(CC)C=1CC1=CC=CC=C1 IOUVKGGHRRTOHA-UHFFFAOYSA-N 0.000 claims 1
• YETRWAVEVYCBJG-UHFFFAOYSA-N 3-benzyl-4-ethyl-5-[(4-methoxyphenyl)methylsulfanyl]-1,2,4-triazole Chemical compound N=1N=C(SCC=2C=CC(OC)=CC=2)N(CC)C=1CC1=CC=CC=C1 YETRWAVEVYCBJG-UHFFFAOYSA-N 0.000 claims 1
• SPGKHGVGMWIKEH-UHFFFAOYSA-N 3-benzyl-4-ethyl-5-[(4-methylphenyl)methylsulfanyl]-1,2,4-triazole Chemical compound N=1N=C(SCC=2C=CC(C)=CC=2)N(CC)C=1CC1=CC=CC=C1 SPGKHGVGMWIKEH-UHFFFAOYSA-N 0.000 claims 1
• DCMJNEXEPFHOJH-UHFFFAOYSA-N 3-benzyl-4-ethyl-5-[(5-methyl-2-nitrophenyl)methylsulfanyl]-1,2,4-triazole Chemical compound N=1N=C(SCC=2C(=CC=C(C)C=2)[N+]([O-])=O)N(CC)C=1CC1=CC=CC=C1 DCMJNEXEPFHOJH-UHFFFAOYSA-N 0.000 claims 1
• DOMVEPZAHSQDKM-UHFFFAOYSA-N 3-benzyl-4-ethyl-5-[[4-(trifluoromethyl)phenyl]methylsulfanyl]-1,2,4-triazole Chemical compound N=1N=C(SCC=2C=CC(=CC=2)C(F)(F)F)N(CC)C=1CC1=CC=CC=C1 DOMVEPZAHSQDKM-UHFFFAOYSA-N 0.000 claims 1
• PSBSJXFQHPXRLP-UHFFFAOYSA-N 3-benzyl-5-[(2,4-dichlorophenyl)methylsulfanyl]-4-ethyl-1,2,4-triazole Chemical compound N=1N=C(SCC=2C(=CC(Cl)=CC=2)Cl)N(CC)C=1CC1=CC=CC=C1 PSBSJXFQHPXRLP-UHFFFAOYSA-N 0.000 claims 1
• OQHBWSLNFUSMQP-UHFFFAOYSA-N 3-benzyl-5-[(2,6-dichlorophenyl)methylsulfanyl]-4-ethyl-1,2,4-triazole Chemical compound N=1N=C(SCC=2C(=CC=CC=2Cl)Cl)N(CC)C=1CC1=CC=CC=C1 OQHBWSLNFUSMQP-UHFFFAOYSA-N 0.000 claims 1
• DBFWVYFXFUDNRN-UHFFFAOYSA-N 3-benzyl-5-[(2-chloro-6-fluorophenyl)methylsulfanyl]-4-methyl-1,2,4-triazole Chemical compound N=1N=C(SCC=2C(=CC=CC=2F)Cl)N(C)C=1CC1=CC=CC=C1 DBFWVYFXFUDNRN-UHFFFAOYSA-N 0.000 claims 1
• DJSHOVRQEUVJFW-UHFFFAOYSA-N 3-benzyl-5-[(3,4-dichlorophenyl)methylsulfanyl]-4-ethyl-1,2,4-triazole Chemical compound N=1N=C(SCC=2C=C(Cl)C(Cl)=CC=2)N(CC)C=1CC1=CC=CC=C1 DJSHOVRQEUVJFW-UHFFFAOYSA-N 0.000 claims 1
• DQRONKYBFVOFDF-UHFFFAOYSA-N 3-benzyl-5-[(3,5-dimethoxyphenyl)methylsulfanyl]-4-ethyl-1,2,4-triazole Chemical compound N=1N=C(SCC=2C=C(OC)C=C(OC)C=2)N(CC)C=1CC1=CC=CC=C1 DQRONKYBFVOFDF-UHFFFAOYSA-N 0.000 claims 1
• HSQIYJMQYYYHJT-UHFFFAOYSA-N 3-benzyl-5-[(4-chlorophenyl)methylsulfanyl]-4-methyl-1,2,4-triazole Chemical compound N=1N=C(SCC=2C=CC(Cl)=CC=2)N(C)C=1CC1=CC=CC=C1 HSQIYJMQYYYHJT-UHFFFAOYSA-N 0.000 claims 1
• ZNTLWYFQGSFBOM-UHFFFAOYSA-N 3-benzyl-5-benzylsulfanyl-4-ethyl-1,2,4-triazole;4-[5-[(2-chloro-6-fluorophenyl)methylsulfanyl]-4-methyl-1,2,4-triazol-3-yl]pyridine Chemical compound N=1N=C(SCC=2C=CC=CC=2)N(CC)C=1CC1=CC=CC=C1.N=1N=C(C=2C=CN=CC=2)N(C)C=1SCC1=C(F)C=CC=C1Cl ZNTLWYFQGSFBOM-UHFFFAOYSA-N 0.000 claims 1
• WYRSPYXQDGIYCX-UHFFFAOYSA-N 3-benzylsulfanyl-4-ethyl-5-(4-nitrophenyl)-1,2,4-triazole Chemical compound N=1N=C(C=2C=CC(=CC=2)[N+]([O-])=O)N(CC)C=1SCC1=CC=CC=C1 WYRSPYXQDGIYCX-UHFFFAOYSA-N 0.000 claims 1
• KMBWUQZURFUDPU-UHFFFAOYSA-N 3-benzylsulfanyl-4-ethyl-5-(5-methylthiophen-2-yl)-1,2,4-triazole Chemical compound N=1N=C(C=2SC(C)=CC=2)N(CC)C=1SCC1=CC=CC=C1 KMBWUQZURFUDPU-UHFFFAOYSA-N 0.000 claims 1
• FTAOJWXRTKNZQX-UHFFFAOYSA-N 3-benzylsulfanyl-4-ethyl-5-[1-phenyl-5-(trifluoromethyl)pyrazol-4-yl]-1,2,4-triazole Chemical compound N=1N=C(C2=C(N(N=C2)C=2C=CC=CC=2)C(F)(F)F)N(CC)C=1SCC1=CC=CC=C1 FTAOJWXRTKNZQX-UHFFFAOYSA-N 0.000 claims 1
• GJFQTEDCEPUYKK-UHFFFAOYSA-N 3-benzylsulfanyl-4-methyl-5-(3,4,5-trimethoxyphenyl)-1,2,4-triazole Chemical compound COC1=C(OC)C(OC)=CC(C=2N(C(SCC=3C=CC=CC=3)=NN=2)C)=C1 GJFQTEDCEPUYKK-UHFFFAOYSA-N 0.000 claims 1
• ICFSYQMPQQLGAZ-UHFFFAOYSA-N 3-benzylsulfanyl-5-(2-methoxyphenyl)-4-methyl-1,2,4-triazole Chemical compound COC1=CC=CC=C1C(N1C)=NN=C1SCC1=CC=CC=C1 ICFSYQMPQQLGAZ-UHFFFAOYSA-N 0.000 claims 1
• QYSKOVQMNNUSSM-UHFFFAOYSA-N 3-benzylsulfanyl-5-(4-bromophenyl)-4-methyl-1,2,4-triazole Chemical compound N=1N=C(C=2C=CC(Br)=CC=2)N(C)C=1SCC1=CC=CC=C1 QYSKOVQMNNUSSM-UHFFFAOYSA-N 0.000 claims 1
• LRXYRGFVYAHAPZ-UHFFFAOYSA-N 3-benzylsulfanyl-5-(4-methoxyphenyl)-4-methyl-1,2,4-triazole Chemical compound C1=CC(OC)=CC=C1C(N1C)=NN=C1SCC1=CC=CC=C1 LRXYRGFVYAHAPZ-UHFFFAOYSA-N 0.000 claims 1
• PTXXAXRTWMNCAY-UHFFFAOYSA-N 3-benzylsulfanyl-5-[(4-chlorophenoxy)methyl]-4-ethyl-1,2,4-triazole Chemical compound N=1N=C(SCC=2C=CC=CC=2)N(CC)C=1COC1=CC=C(Cl)C=C1 PTXXAXRTWMNCAY-UHFFFAOYSA-N 0.000 claims 1
• CTLUIFMJDKYDLR-UHFFFAOYSA-N 3-benzylsulfanyl-5-[4-(2,5-dimethylpyrrol-1-yl)phenyl]-4-ethyl-1,2,4-triazole Chemical compound N=1N=C(C=2C=CC(=CC=2)N2C(=CC=C2C)C)N(CC)C=1SCC1=CC=CC=C1 CTLUIFMJDKYDLR-UHFFFAOYSA-N 0.000 claims 1
• TVCPFXRYXOOVCW-UHFFFAOYSA-N 3-bicyclo[2.2.1]heptanyl-[4-(2,3-dimethylphenyl)piperazin-1-yl]methanone Chemical compound CC1=CC=CC(N2CCN(CC2)C(=O)C2C3CCC(C3)C2)=C1C TVCPFXRYXOOVCW-UHFFFAOYSA-N 0.000 claims 1
• VGOUETQRBKNMCS-UHFFFAOYSA-N 3-bicyclo[2.2.1]heptanyl-[4-(2-ethoxyphenyl)piperazin-1-yl]methanone Chemical compound CCOC1=CC=CC=C1N1CCN(C(=O)C2C3CCC(C3)C2)CC1 VGOUETQRBKNMCS-UHFFFAOYSA-N 0.000 claims 1
• MXPUPKZRQSPLBY-UHFFFAOYSA-N 3-bromo-5-(4-bromophenyl)-N-cyclohexyl-N-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide Chemical compound N=1N2C(C(F)(F)F)=CC(C=3C=CC(Br)=CC=3)=NC2=C(Br)C=1C(=O)N(C)C1CCCCC1 MXPUPKZRQSPLBY-UHFFFAOYSA-N 0.000 claims 1
• SXYTYMZPKCYNCQ-UHFFFAOYSA-N 3-bromo-N-[3-methyl-1-oxo-1-(3,3,5-trimethyl-7-azabicyclo[3.2.1]octan-7-yl)pentan-2-yl]benzamide Chemical compound C1C(CC(C)(C)C2)(C)CC2N1C(=O)C(C(C)CC)NC(=O)C1=CC=CC(Br)=C1 SXYTYMZPKCYNCQ-UHFFFAOYSA-N 0.000 claims 1
• CTXXXHCJUJZTKC-UHFFFAOYSA-N 3-bromo-N-cyclohexyl-5-(furan-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide Chemical compound N=1N2C(C(F)(F)F)=CC(C=3OC=CC=3)=NC2=C(Br)C=1C(=O)NC1CCCCC1 CTXXXHCJUJZTKC-UHFFFAOYSA-N 0.000 claims 1
• SPCUVPOVZSGXTC-UHFFFAOYSA-N 3-bromo-N-cyclohexyl-N-methyl-5-thiophen-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide Chemical compound N=1N2C(C(F)(F)F)=CC(C=3SC=CC=3)=NC2=C(Br)C=1C(=O)N(C)C1CCCCC1 SPCUVPOVZSGXTC-UHFFFAOYSA-N 0.000 claims 1
• ZAUZWUWDJQIXBT-UHFFFAOYSA-N 3-butylsulfanyl-4-methyl-5-(4-methylphenyl)-1,2,4-triazole Chemical compound CN1C(SCCCC)=NN=C1C1=CC=C(C)C=C1 ZAUZWUWDJQIXBT-UHFFFAOYSA-N 0.000 claims 1
• BEZMPZHXXHOHJX-UHFFFAOYSA-N 3-butylsulfanyl-5-(4-methoxyphenyl)-4-methyl-1,2,4-triazole Chemical compound CN1C(SCCCC)=NN=C1C1=CC=C(OC)C=C1 BEZMPZHXXHOHJX-UHFFFAOYSA-N 0.000 claims 1
• LHOPHTDOMJORCU-UHFFFAOYSA-N 3-chloro-5-(4-methoxyphenyl)-N-methyl-N-(2-pyridin-2-ylethyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide Chemical compound C1=CC(OC)=CC=C1C1=NC2=C(Cl)C(C(=O)N(C)CCC=3N=CC=CC=3)=NN2C(C(F)(F)F)=C1 LHOPHTDOMJORCU-UHFFFAOYSA-N 0.000 claims 1
• NIBGOYHSCONGHL-UHFFFAOYSA-N 3-chloro-N-(2-cyanoethyl)-N-cyclohexyl-1-benzothiophene-2-carboxamide Chemical compound S1C2=CC=CC=C2C(Cl)=C1C(=O)N(CCC#N)C1CCCCC1 NIBGOYHSCONGHL-UHFFFAOYSA-N 0.000 claims 1
• KSKRUVPZJQYBJY-UHFFFAOYSA-N 3-chloro-N-(2-cyanoethyl)-N-phenyl-1-benzothiophene-2-carboxamide Chemical compound S1C2=CC=CC=C2C(Cl)=C1C(=O)N(CCC#N)C1=CC=CC=C1 KSKRUVPZJQYBJY-UHFFFAOYSA-N 0.000 claims 1
• LMQVACPEALDOMF-UHFFFAOYSA-N 3-chloro-N-[(1,3-dimethylpyrazol-4-yl)methyl]-5-(4-methoxyphenyl)-N-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide Chemical compound C1=CC(OC)=CC=C1C1=NC2=C(Cl)C(C(=O)N(C)CC=3C(=NN(C)C=3)C)=NN2C(C(F)(F)F)=C1 LMQVACPEALDOMF-UHFFFAOYSA-N 0.000 claims 1
• XPEJXIXVBXJDGH-UHFFFAOYSA-N 3-chloro-N-cyclohexyl-5-(4-methoxyphenyl)-N-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide Chemical compound C1=CC(OC)=CC=C1C1=NC2=C(Cl)C(C(=O)N(C)C3CCCCC3)=NN2C(C(F)(F)F)=C1 XPEJXIXVBXJDGH-UHFFFAOYSA-N 0.000 claims 1
• 125000004179 3-chlorophenyl group Chemical group [H]C1=C([H])C(*)=C([H])C(Cl)=C1[H] 0.000 claims 1
• HEEDMMBEBQVQSK-UHFFFAOYSA-N 3-cyclohexyl-1-[4-(1H-imidazol-5-yl)piperidin-1-yl]propan-1-one Chemical compound C1CC(C=2N=CNC=2)CCN1C(=O)CCC1CCCCC1 HEEDMMBEBQVQSK-UHFFFAOYSA-N 0.000 claims 1
• ARIRKQATFICMBJ-UHFFFAOYSA-N 3-cyclohexyl-4-methyl-5-[(4-methylphenyl)methylsulfanyl]-1,2,4-triazole Chemical compound C1=CC(C)=CC=C1CSC(N1C)=NN=C1C1CCCCC1 ARIRKQATFICMBJ-UHFFFAOYSA-N 0.000 claims 1
• NUNQOEASBHTZFI-UHFFFAOYSA-N 3-cyclohexyl-N-(3-phenylpropyl)propanamide Chemical compound C=1C=CC=CC=1CCCNC(=O)CCC1CCCCC1 NUNQOEASBHTZFI-UHFFFAOYSA-N 0.000 claims 1
• VIAZKZSZTPUSTN-UHFFFAOYSA-N 3-cyclopentyl-1-(6-fluoro-2-methyl-3,4-dihydro-2H-quinolin-1-yl)propan-1-one Chemical compound CC1CCC2=CC(F)=CC=C2N1C(=O)CCC1CCCC1 VIAZKZSZTPUSTN-UHFFFAOYSA-N 0.000 claims 1
• RSLXYRBJGGKEOQ-UHFFFAOYSA-N 3-cyclopentyl-N-[(4-methylphenyl)methyl]-N-[6-(pyridin-2-ylamino)hexyl]propanamide Chemical compound C1=CC(C)=CC=C1CN(C(=O)CCC1CCCC1)CCCCCCNC1=CC=CC=N1 RSLXYRBJGGKEOQ-UHFFFAOYSA-N 0.000 claims 1
• KPZWEVYTOHWSCX-UHFFFAOYSA-N 3-cyclopentyl-N-[1-[4-(3-cyclopentylpropanoyl)piperazin-1-yl]-1-oxo-3-phenylpropan-2-yl]propanamide Chemical compound C=1C=CC=CC=1CC(C(=O)N1CCN(CC1)C(=O)CCC1CCCC1)NC(=O)CCC1CCCC1 KPZWEVYTOHWSCX-UHFFFAOYSA-N 0.000 claims 1
• DAMPQIDCRXXMOX-UHFFFAOYSA-N 3-cyclopentyl-N-[3-methyl-1-oxo-1-(3,3,5-trimethyl-7-azabicyclo[3.2.1]octan-7-yl)pentan-2-yl]propanamide Chemical compound C1C(CC(C)(C)C2)(C)CC2N1C(=O)C(C(C)CC)NC(=O)CCC1CCCC1 DAMPQIDCRXXMOX-UHFFFAOYSA-N 0.000 claims 1
• WGJNCXLHFMFLPI-UHFFFAOYSA-N 3-methoxy-N-(2-methoxyethyl)-N-(2-piperidin-4-ylethyl)-5-(pyridine-2-carbonyl)benzamide Chemical compound C=1C(OC)=CC(C(=O)C=2N=CC=CC=2)=CC=1C(=O)N(CCOC)CCC1CCNCC1 WGJNCXLHFMFLPI-UHFFFAOYSA-N 0.000 claims 1
• JEAJGACHSHBSHS-UHFFFAOYSA-N 3-methoxy-N-(2-methoxyethyl)-N-(piperidin-3-ylmethyl)-5-(pyridine-2-carbonyl)benzamide Chemical compound C=1C(OC)=CC(C(=O)C=2N=CC=CC=2)=CC=1C(=O)N(CCOC)CC1CCCNC1 JEAJGACHSHBSHS-UHFFFAOYSA-N 0.000 claims 1
• SRKVNGUVRVMENY-UHFFFAOYSA-N 3-methoxy-N-(2-oxoazepan-3-yl)-N-(2-piperidin-4-ylethyl)-5-(pyridine-2-carbonyl)benzamide Chemical compound C=1C(OC)=CC(C(=O)N(CCC2CCNCC2)C2C(NCCCC2)=O)=CC=1C(=O)C1=CC=CC=N1 SRKVNGUVRVMENY-UHFFFAOYSA-N 0.000 claims 1
• YRNDALDPZKCGLP-UHFFFAOYSA-N 3-methoxy-N-(oxolan-2-ylmethyl)-N-(2-piperidin-4-ylethyl)-5-(pyridine-2-carbonyl)benzamide Chemical compound C=1C(OC)=CC(C(=O)N(CCC2CCNCC2)CC2OCCC2)=CC=1C(=O)C1=CC=CC=N1 YRNDALDPZKCGLP-UHFFFAOYSA-N 0.000 claims 1
• XXDQRLVBJNMLOG-UHFFFAOYSA-N 3-methoxy-N-[3-(2-oxopyrrolidin-1-yl)propyl]-5-(pyridine-2-carbonyl)benzamide Chemical compound C=1C(OC)=CC(C(=O)NCCCN2C(CCC2)=O)=CC=1C(=O)C1=CC=CC=N1 XXDQRLVBJNMLOG-UHFFFAOYSA-N 0.000 claims 1
• TTXDWKTUIVFROG-UHFFFAOYSA-N 3-methoxy-N-[3-(2-oxopyrrolidin-1-yl)propyl]-N-(2-piperidin-4-ylethyl)-5-(pyridine-2-carbonyl)benzamide Chemical compound C=1C(OC)=CC(C(=O)N(CCCN2C(CCC2)=O)CCC2CCNCC2)=CC=1C(=O)C1=CC=CC=N1 TTXDWKTUIVFROG-UHFFFAOYSA-N 0.000 claims 1
• ZIFMGUQIQKOMTE-UHFFFAOYSA-N 3-methoxy-N-methyl-N-(2-piperidin-4-ylethyl)-5-(pyridine-2-carbonyl)benzamide Chemical compound C=1C(OC)=CC(C(=O)N(C)CCC2CCNCC2)=CC=1C(=O)C1=CC=CC=N1 ZIFMGUQIQKOMTE-UHFFFAOYSA-N 0.000 claims 1
• YNCFPURBKVPYQF-UHFFFAOYSA-N 3-phenyl-6,7,8,9-tetrahydro-5H-[1,2,4]triazolo[4,3-a]azepine Chemical compound N12CCCCCC2=NN=C1C1=CC=CC=C1 YNCFPURBKVPYQF-UHFFFAOYSA-N 0.000 claims 1
• NVZFJWSRMJTYGR-UHFFFAOYSA-N 3-phenyl-N-(1-phenylpropan-2-yl)propanamide Chemical compound C=1C=CC=CC=1CCC(=O)NC(C)CC1=CC=CC=C1 NVZFJWSRMJTYGR-UHFFFAOYSA-N 0.000 claims 1
• XCNFBPXYJPORHD-UHFFFAOYSA-N 3-pyridin-3-yl-6,7,8,9-tetrahydro-5H-[1,2,4]triazolo[4,3-a]azepine Chemical compound N12CCCCCC2=NN=C1C1=CC=CN=C1 XCNFBPXYJPORHD-UHFFFAOYSA-N 0.000 claims 1
• RZQQPARKDTYYBY-UHFFFAOYSA-N 3-pyridin-4-yl-6,7,8,9-tetrahydro-5H-[1,2,4]triazolo[4,3-a]azepine Chemical compound N12CCCCCC2=NN=C1C1=CC=NC=C1 RZQQPARKDTYYBY-UHFFFAOYSA-N 0.000 claims 1
• IVQSWGRXIWBWGA-UHFFFAOYSA-N 4-(2,4-dichlorophenoxy)-1-(4-phenylpiperazin-1-yl)butan-1-one Chemical compound ClC1=CC(Cl)=CC=C1OCCCC(=O)N1CCN(C=2C=CC=CC=2)CC1 IVQSWGRXIWBWGA-UHFFFAOYSA-N 0.000 claims 1
• MLHGNSOMRCPHGF-UHFFFAOYSA-N 4-(2,4-dichlorophenoxy)-1-[4-(4-fluorophenyl)piperazin-1-yl]butan-1-one Chemical compound C1=CC(F)=CC=C1N1CCN(C(=O)CCCOC=2C(=CC(Cl)=CC=2)Cl)CC1 MLHGNSOMRCPHGF-UHFFFAOYSA-N 0.000 claims 1
• LRFPRQXBDQUNSP-UHFFFAOYSA-N 4-(2,4-dichlorophenoxy)-1-piperidin-1-ylbutan-1-one Chemical compound ClC1=CC(Cl)=CC=C1OCCCC(=O)N1CCCCC1 LRFPRQXBDQUNSP-UHFFFAOYSA-N 0.000 claims 1
• HTFAPKQXWFGTTN-UHFFFAOYSA-N 4-(2,6-dichlorophenyl)sulfanyl-N-[(6,6-dimethyl-4-bicyclo[3.1.1]heptanyl)methyl]butanamide Chemical compound CC1(C)C(CC2)CC1C2CNC(=O)CCCSC1=C(Cl)C=CC=C1Cl HTFAPKQXWFGTTN-UHFFFAOYSA-N 0.000 claims 1
• RCLJQROXNMOEMP-UHFFFAOYSA-N 4-(2-methoxyethyl)-3-(2-methoxyethylsulfanyl)-5-(2-methoxyphenyl)-1,2,4-triazole Chemical compound COCCN1C(SCCOC)=NN=C1C1=CC=CC=C1OC RCLJQROXNMOEMP-UHFFFAOYSA-N 0.000 claims 1
• VIOJWBKZFNFVQY-UHFFFAOYSA-N 4-(2-methoxyethyl)-3-(2-methoxyethylsulfanyl)-5-thiophen-2-yl-1,2,4-triazole Chemical compound COCCN1C(SCCOC)=NN=C1C1=CC=CS1 VIOJWBKZFNFVQY-UHFFFAOYSA-N 0.000 claims 1
• CZNDCWPMEWXZST-UHFFFAOYSA-N 4-(2-methylprop-2-enyl)-3-(3-nitrophenyl)-1H-1,2,4-triazole-5-thione Chemical compound N1C(=S)N(CC(=C)C)C(C=2C=C(C=CC=2)[N+]([O-])=O)=N1 CZNDCWPMEWXZST-UHFFFAOYSA-N 0.000 claims 1
• CFIUCNIQKGZBST-UHFFFAOYSA-N 4-(3,3,5-trimethyl-7-azabicyclo[3.2.1]octane-7-carbonyl)benzoic acid Chemical compound C1C(C)(C)CC(C)(C2)CC1N2C(=O)C1=CC=C(C(O)=O)C=C1 CFIUCNIQKGZBST-UHFFFAOYSA-N 0.000 claims 1
• BCOOHAJVMHYSQG-UHFFFAOYSA-N 4-(3,4-dihydro-1H-isoquinoline-2-carbonyl)-1,7,7-trimethyl-3-oxabicyclo[2.2.1]heptan-2-one Chemical compound C1CC2=CC=CC=C2CN1C(=O)C1(OC2=O)CCC2(C)C1(C)C BCOOHAJVMHYSQG-UHFFFAOYSA-N 0.000 claims 1
• ABWBCQMJMOTENL-UHFFFAOYSA-N 4-(3,4-dihydro-2H-quinoline-1-carbonyl)-1,7,7-trimethyl-3-oxabicyclo[2.2.1]heptan-2-one Chemical compound C1CCC2=CC=CC=C2N1C(=O)C1(OC2=O)CCC2(C)C1(C)C ABWBCQMJMOTENL-UHFFFAOYSA-N 0.000 claims 1
• HKTQOOXXOJKOIL-UHFFFAOYSA-N 4-(3-azabicyclo[3.2.2]nonane-3-carbonyl)-N,N-dipropylbenzenesulfonamide Chemical compound C1=CC(S(=O)(=O)N(CCC)CCC)=CC=C1C(=O)N1CC(CC2)CCC2C1 HKTQOOXXOJKOIL-UHFFFAOYSA-N 0.000 claims 1
• GZLLPIMYJDCWRW-UHFFFAOYSA-N 4-(3-benzylsulfanyl-4-ethyl-1H-1,2,4-triazol-5-ylidene)cyclohexa-2,5-dien-1-one Chemical compound N=1NC(=C2C=CC(=O)C=C2)N(CC)C=1SCC1=CC=CC=C1 GZLLPIMYJDCWRW-UHFFFAOYSA-N 0.000 claims 1
• YZQPOZMTRZGJNZ-UHFFFAOYSA-N 4-(4-bromophenyl)-N-[(2-hydroxyphenyl)methyl]-4-oxo-N-(thiophen-2-ylmethyl)butanamide Chemical compound OC1=CC=CC=C1CN(C(=O)CCC(=O)C=1C=CC(Br)=CC=1)CC1=CC=CS1 YZQPOZMTRZGJNZ-UHFFFAOYSA-N 0.000 claims 1
• IGNMXUGQHJGRQL-UHFFFAOYSA-N 4-(4-chloro-2-methylphenoxy)-1-(3,4-dihydro-2H-quinolin-1-yl)butan-1-one Chemical compound CC1=CC(Cl)=CC=C1OCCCC(=O)N1C2=CC=CC=C2CCC1 IGNMXUGQHJGRQL-UHFFFAOYSA-N 0.000 claims 1
• IDADHKJDWBLCBE-UHFFFAOYSA-N 4-(4-methoxy-3-methylphenyl)-N-(2-methylcyclohexyl)butanamide Chemical compound C1=C(C)C(OC)=CC=C1CCCC(=O)NC1C(C)CCCC1 IDADHKJDWBLCBE-UHFFFAOYSA-N 0.000 claims 1
• KYIKZOGFMWXIHE-UHFFFAOYSA-N 4-(4-methyl-3-phenacylsulfanyl-1H-1,2,4-triazol-5-ylidene)cyclohexa-2,5-dien-1-one Chemical compound N=1NC(=C2C=CC(=O)C=C2)N(C)C=1SCC(=O)C1=CC=CC=C1 KYIKZOGFMWXIHE-UHFFFAOYSA-N 0.000 claims 1
• RJOVTFLRCHEABJ-UHFFFAOYSA-N 4-(5,5-dimethyl-2,6-dihydro-[1,2,4]triazolo[3,4-a]isoquinolin-3-ylidene)cyclohexa-2,5-dien-1-one Chemical compound N12C(C)(C)CC3=CC=CC=C3C2=NNC1=C1C=CC(=O)C=C1 RJOVTFLRCHEABJ-UHFFFAOYSA-N 0.000 claims 1
• JCZBBVNPUTYAAC-UHFFFAOYSA-N 4-(cyclopropylmethyl)-3-(2-methoxyethylsulfanyl)-5-(2-methoxyphenyl)-1,2,4-triazole Chemical compound C1CC1CN1C(SCCOC)=NN=C1C1=CC=CC=C1OC JCZBBVNPUTYAAC-UHFFFAOYSA-N 0.000 claims 1
• RXMBMELQHQSJGV-UHFFFAOYSA-N 4-(cyclopropylmethyl)-3-(2-methoxyethylsulfanyl)-5-thiophen-2-yl-1,2,4-triazole Chemical compound C1CC1CN1C(SCCOC)=NN=C1C1=CC=CS1 RXMBMELQHQSJGV-UHFFFAOYSA-N 0.000 claims 1
• ULVGPDHDQCFQNY-UHFFFAOYSA-N 4-[(4-ethyl-5-pyridin-2-yl-1,2,4-triazol-3-yl)sulfanylmethyl]benzonitrile Chemical compound N=1N=C(C=2N=CC=CC=2)N(CC)C=1SCC1=CC=C(C#N)C=C1 ULVGPDHDQCFQNY-UHFFFAOYSA-N 0.000 claims 1
• QYHXSEZWVZUXTI-UHFFFAOYSA-N 4-[(4-ethyl-5-pyridin-3-yl-1,2,4-triazol-3-yl)sulfanylmethyl]benzonitrile Chemical compound N=1N=C(C=2C=NC=CC=2)N(CC)C=1SCC1=CC=C(C#N)C=C1 QYHXSEZWVZUXTI-UHFFFAOYSA-N 0.000 claims 1
• JFNZJTCAVNOXBH-UHFFFAOYSA-N 4-[(4-ethyl-5-pyridin-4-yl-1,2,4-triazol-3-yl)sulfanylmethyl]benzonitrile Chemical compound N=1N=C(C=2C=CN=CC=2)N(CC)C=1SCC1=CC=C(C#N)C=C1 JFNZJTCAVNOXBH-UHFFFAOYSA-N 0.000 claims 1
• NJXJQFGWDYJOCB-UHFFFAOYSA-N 4-[(4-ethyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanylmethyl]benzonitrile Chemical compound N=1N=C(C=2SC=CC=2)N(CC)C=1SCC1=CC=C(C#N)C=C1 NJXJQFGWDYJOCB-UHFFFAOYSA-N 0.000 claims 1
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• UWRNQBNLENHGBY-UHFFFAOYSA-N 4-[2-(2,6-dichlorophenyl)sulfanylethyl]-N-[2-(2-fluorophenyl)ethyl]benzamide Chemical compound FC1=CC=CC=C1CCNC(=O)C(C=C1)=CC=C1CCSC1=C(Cl)C=CC=C1Cl UWRNQBNLENHGBY-UHFFFAOYSA-N 0.000 claims 1
• FKZKHWLNLOEBAC-UHFFFAOYSA-N 4-[2-[(4-ethyl-5-pyridin-4-yl-1,2,4-triazol-3-yl)sulfanyl]ethyl]morpholine Chemical compound N=1N=C(C=2C=CN=CC=2)N(CC)C=1SCCN1CCOCC1 FKZKHWLNLOEBAC-UHFFFAOYSA-N 0.000 claims 1
• ASMFDWSWECSQNX-UHFFFAOYSA-N 4-[3-[(2,4-dichlorophenyl)methylsulfanyl]-4-ethyl-1H-1,2,4-triazol-5-ylidene]cyclohexa-2,5-dien-1-one Chemical compound N=1NC(=C2C=CC(=O)C=C2)N(CC)C=1SCC1=CC=C(Cl)C=C1Cl ASMFDWSWECSQNX-UHFFFAOYSA-N 0.000 claims 1
• YZEQLAGLWUAONF-UHFFFAOYSA-N 4-[3-[(4-chlorophenyl)methylsulfanyl]-4-ethyl-1H-1,2,4-triazol-5-ylidene]cyclohexa-2,5-dien-1-one Chemical compound N=1NC(=C2C=CC(=O)C=C2)N(CC)C=1SCC1=CC=C(Cl)C=C1 YZEQLAGLWUAONF-UHFFFAOYSA-N 0.000 claims 1
• KEZYIBTUTKUSIH-UHFFFAOYSA-N 4-[3-[(4-chlorophenyl)methylsulfanyl]-4-methyl-1H-1,2,4-triazol-5-ylidene]cyclohexa-2,5-dien-1-one Chemical compound N=1NC(=C2C=CC(=O)C=C2)N(C)C=1SCC1=CC=C(Cl)C=C1 KEZYIBTUTKUSIH-UHFFFAOYSA-N 0.000 claims 1
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• CBLGYZSCFONDCM-UHFFFAOYSA-N 4-[4-[(4-ethyl-5-pyridin-2-yl-1,2,4-triazol-3-yl)sulfanylmethyl]phenyl]thiadiazole Chemical compound N=1N=C(C=2N=CC=CC=2)N(CC)C=1SCC(C=C1)=CC=C1C1=CSN=N1 CBLGYZSCFONDCM-UHFFFAOYSA-N 0.000 claims 1
• YZPPYFXZDDQXQB-UHFFFAOYSA-N 4-[4-[(4-ethyl-5-pyridin-3-yl-1,2,4-triazol-3-yl)sulfanylmethyl]phenyl]thiadiazole Chemical compound N=1N=C(C=2C=NC=CC=2)N(CC)C=1SCC(C=C1)=CC=C1C1=CSN=N1 YZPPYFXZDDQXQB-UHFFFAOYSA-N 0.000 claims 1
• GPDLQULFHHPNGY-UHFFFAOYSA-N 4-[4-[(4-ethyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanylmethyl]phenyl]thiadiazole Chemical compound N=1N=C(C=2SC=CC=2)N(CC)C=1SCC(C=C1)=CC=C1C1=CSN=N1 GPDLQULFHHPNGY-UHFFFAOYSA-N 0.000 claims 1
• XHXDJDGNDJOWIH-UHFFFAOYSA-N 4-[4-[(5-benzyl-4-ethyl-1,2,4-triazol-3-yl)sulfanylmethyl]phenyl]thiadiazole Chemical compound N=1N=C(SCC=2C=CC(=CC=2)C=2N=NSC=2)N(CC)C=1CC1=CC=CC=C1 XHXDJDGNDJOWIH-UHFFFAOYSA-N 0.000 claims 1
• DVTPGYSWFFEQDH-UHFFFAOYSA-N 4-[4-[2-[4-(dimethylamino)phenyl]acetyl]piperazin-1-yl]-3-(2-phenylpropylamino)benzamide Chemical compound C=1C=CC=CC=1C(C)CNC1=CC(C(N)=O)=CC=C1N(CC1)CCN1C(=O)CC1=CC=C(N(C)C)C=C1 DVTPGYSWFFEQDH-UHFFFAOYSA-N 0.000 claims 1
• FYQXJPPEYPXUJN-UHFFFAOYSA-N 4-[4-[[4-ethyl-5-(2-methylsulfanylpyridin-3-yl)-1,2,4-triazol-3-yl]sulfanylmethyl]phenyl]thiadiazole Chemical compound N=1N=C(C=2C(=NC=CC=2)SC)N(CC)C=1SCC(C=C1)=CC=C1C1=CSN=N1 FYQXJPPEYPXUJN-UHFFFAOYSA-N 0.000 claims 1
• GTNQPQNVLRLTCQ-UHFFFAOYSA-N 4-[4-[[4-ethyl-5-(2-phenoxyphenyl)-1,2,4-triazol-3-yl]sulfanylmethyl]phenyl]thiadiazole Chemical compound N=1N=C(C=2C(=CC=CC=2)OC=2C=CC=CC=2)N(CC)C=1SCC(C=C1)=CC=C1C1=CSN=N1 GTNQPQNVLRLTCQ-UHFFFAOYSA-N 0.000 claims 1
• KQDRKEZEXONQKL-UHFFFAOYSA-N 4-[4-[[4-ethyl-5-(4-methoxyphenyl)-1,2,4-triazol-3-yl]sulfanylmethyl]phenyl]thiadiazole Chemical compound N=1N=C(C=2C=CC(OC)=CC=2)N(CC)C=1SCC(C=C1)=CC=C1C1=CSN=N1 KQDRKEZEXONQKL-UHFFFAOYSA-N 0.000 claims 1
• RTHARHUIYLMPDW-UHFFFAOYSA-N 4-[4-[[4-ethyl-5-[1-phenyl-5-(trifluoromethyl)pyrazol-4-yl]-1,2,4-triazol-3-yl]sulfanylmethyl]phenyl]thiadiazole Chemical compound N=1N=C(C2=C(N(N=C2)C=2C=CC=CC=2)C(F)(F)F)N(CC)C=1SCC(C=C1)=CC=C1C1=CSN=N1 RTHARHUIYLMPDW-UHFFFAOYSA-N 0.000 claims 1
• GMJPFABIFVCPAX-UHFFFAOYSA-N 4-[4-[[4-methyl-5-(5-methylthiophen-2-yl)-1,2,4-triazol-3-yl]sulfanylmethyl]phenyl]thiadiazole Chemical compound S1C(C)=CC=C1C(N1C)=NN=C1SCC1=CC=C(C=2N=NSC=2)C=C1 GMJPFABIFVCPAX-UHFFFAOYSA-N 0.000 claims 1
• BGBGYKQVRVOOJF-UHFFFAOYSA-N 4-[4-[[5-(1,3-benzodioxol-5-yl)-4-ethyl-1,2,4-triazol-3-yl]sulfanylmethyl]phenyl]thiadiazole Chemical compound N=1N=C(C=2C=C3OCOC3=CC=2)N(CC)C=1SCC(C=C1)=CC=C1C1=CSN=N1 BGBGYKQVRVOOJF-UHFFFAOYSA-N 0.000 claims 1
• LFJYRICFGCWGLX-UHFFFAOYSA-N 4-[4-[[5-(1-benzothiophen-2-yl)-4-ethyl-1,2,4-triazol-3-yl]sulfanylmethyl]phenyl]thiadiazole Chemical compound N=1N=C(C=2SC3=CC=CC=C3C=2)N(CC)C=1SCC(C=C1)=CC=C1C1=CSN=N1 LFJYRICFGCWGLX-UHFFFAOYSA-N 0.000 claims 1
• XCUPFZHLHYDCNX-UHFFFAOYSA-N 4-[4-[[5-(3-chloro-4-methylthiophen-2-yl)-4-ethyl-1,2,4-triazol-3-yl]sulfanylmethyl]phenyl]thiadiazole Chemical compound N=1N=C(C2=C(C(C)=CS2)Cl)N(CC)C=1SCC(C=C1)=CC=C1C1=CSN=N1 XCUPFZHLHYDCNX-UHFFFAOYSA-N 0.000 claims 1
• BMMUAFBXVFHGPP-UHFFFAOYSA-N 4-[4-[[5-(4-chlorophenyl)-4-ethyl-1,2,4-triazol-3-yl]sulfanylmethyl]phenyl]thiadiazole Chemical compound N=1N=C(C=2C=CC(Cl)=CC=2)N(CC)C=1SCC(C=C1)=CC=C1C1=CSN=N1 BMMUAFBXVFHGPP-UHFFFAOYSA-N 0.000 claims 1
• RYWLDCMGGNRWLC-UHFFFAOYSA-N 4-[4-[[5-(5-chlorothiophen-2-yl)-4-ethyl-1,2,4-triazol-3-yl]sulfanylmethyl]phenyl]thiadiazole Chemical compound N=1N=C(C=2SC(Cl)=CC=2)N(CC)C=1SCC(C=C1)=CC=C1C1=CSN=N1 RYWLDCMGGNRWLC-UHFFFAOYSA-N 0.000 claims 1
• MXRDZHAYTHVKIY-UHFFFAOYSA-N 4-[4-ethyl-5-[(4-methoxyphenyl)methylsulfanyl]-1,2,4-triazol-3-yl]-N,N-dimethylaniline Chemical compound N=1N=C(C=2C=CC(=CC=2)N(C)C)N(CC)C=1SCC1=CC=C(OC)C=C1 MXRDZHAYTHVKIY-UHFFFAOYSA-N 0.000 claims 1
• APUOSMIWAIFJBP-UHFFFAOYSA-N 4-[4-ethyl-5-[(4-methylphenyl)methylsulfanyl]-1,2,4-triazol-3-yl]pyridine Chemical compound N=1N=C(C=2C=CN=CC=2)N(CC)C=1SCC1=CC=C(C)C=C1 APUOSMIWAIFJBP-UHFFFAOYSA-N 0.000 claims 1
• IOZSWHQHVPBNGE-UHFFFAOYSA-N 4-[4-ethyl-5-[(4-methylsulfonylphenyl)methylsulfanyl]-1,2,4-triazol-3-yl]pyridine Chemical compound N=1N=C(C=2C=CN=CC=2)N(CC)C=1SCC1=CC=C(S(C)(=O)=O)C=C1 IOZSWHQHVPBNGE-UHFFFAOYSA-N 0.000 claims 1
• ONPJCEYLMNBNRD-UHFFFAOYSA-N 4-[4-ethyl-5-[(4-nitrophenyl)methylsulfanyl]-1,2,4-triazol-3-yl]-N,N-dimethylaniline Chemical compound N=1N=C(C=2C=CC(=CC=2)N(C)C)N(CC)C=1SCC1=CC=C([N+]([O-])=O)C=C1 ONPJCEYLMNBNRD-UHFFFAOYSA-N 0.000 claims 1
• VLMPNOBPFDZHGP-UHFFFAOYSA-N 4-[4-ethyl-5-[(5-methyl-2-nitrophenyl)methylsulfanyl]-1,2,4-triazol-3-yl]-N,N-dimethylaniline Chemical compound N=1N=C(C=2C=CC(=CC=2)N(C)C)N(CC)C=1SCC1=CC(C)=CC=C1[N+]([O-])=O VLMPNOBPFDZHGP-UHFFFAOYSA-N 0.000 claims 1
• LCAHTRHNNGPQBQ-UHFFFAOYSA-N 4-[4-ethyl-5-[[3-(trifluoromethoxy)phenyl]methylsulfanyl]-1,2,4-triazol-3-yl]pyridine Chemical compound N=1N=C(C=2C=CN=CC=2)N(CC)C=1SCC1=CC=CC(OC(F)(F)F)=C1 LCAHTRHNNGPQBQ-UHFFFAOYSA-N 0.000 claims 1
• QGMRICCOCAZISZ-UHFFFAOYSA-N 4-[5-(6,7,8,9-tetrahydro-5H-[1,2,4]triazolo[4,3-a]azepin-3-yl)pyridin-2-yl]morpholine Chemical compound C1COCCN1C1=CC=C(C=2N3CCCCCC3=NN=2)C=N1 QGMRICCOCAZISZ-UHFFFAOYSA-N 0.000 claims 1
• IDNWCNHKUOMRRB-UHFFFAOYSA-N 4-[5-[(2,4-dichlorophenyl)methylsulfanyl]-4-ethyl-1,2,4-triazol-3-yl]-N,N-dimethylaniline Chemical compound N=1N=C(C=2C=CC(=CC=2)N(C)C)N(CC)C=1SCC1=CC=C(Cl)C=C1Cl IDNWCNHKUOMRRB-UHFFFAOYSA-N 0.000 claims 1
• HLZVIUZAYFVDSA-UHFFFAOYSA-N 4-[5-[(2,6-dichlorophenyl)methylsulfanyl]-4-(furan-2-ylmethyl)-1,2,4-triazol-3-yl]pyridine Chemical compound ClC1=CC=CC(Cl)=C1CSC(N1CC=2OC=CC=2)=NN=C1C1=CC=NC=C1 HLZVIUZAYFVDSA-UHFFFAOYSA-N 0.000 claims 1
• HBFZEYNUJRHTKB-UHFFFAOYSA-N 4-[5-[(2,6-dichlorophenyl)methylsulfanyl]-4-(oxolan-2-ylmethyl)-1,2,4-triazol-3-yl]pyridine Chemical compound ClC1=CC=CC(Cl)=C1CSC(N1CC2OCCC2)=NN=C1C1=CC=NC=C1 HBFZEYNUJRHTKB-UHFFFAOYSA-N 0.000 claims 1
• ZHOYYBOHVOLBKW-UHFFFAOYSA-N 4-[5-[(3,5-dimethoxyphenyl)methylsulfanyl]-4-ethyl-1,2,4-triazol-3-yl]pyridine Chemical compound N=1N=C(C=2C=CN=CC=2)N(CC)C=1SCC1=CC(OC)=CC(OC)=C1 ZHOYYBOHVOLBKW-UHFFFAOYSA-N 0.000 claims 1
• RLTJGWZANMGDJP-UHFFFAOYSA-N 4-[5-[(4-bromophenyl)methylsulfanyl]-4-ethyl-1,2,4-triazol-3-yl]pyridine Chemical compound N=1N=C(C=2C=CN=CC=2)N(CC)C=1SCC1=CC=C(Br)C=C1 RLTJGWZANMGDJP-UHFFFAOYSA-N 0.000 claims 1
• OUFPCLUUQYRIQE-UHFFFAOYSA-N 4-[5-[(4-chlorophenyl)methylsulfanyl]-4-methyl-1,2,4-triazol-3-yl]aniline Chemical compound N=1N=C(C=2C=CC(N)=CC=2)N(C)C=1SCC1=CC=C(Cl)C=C1 OUFPCLUUQYRIQE-UHFFFAOYSA-N 0.000 claims 1
• PIASNQAKAMXOQL-UHFFFAOYSA-N 4-[5-[(4-tert-butylphenyl)methylsulfanyl]-4-ethyl-1,2,4-triazol-3-yl]pyridine Chemical compound N=1N=C(C=2C=CN=CC=2)N(CC)C=1SCC1=CC=C(C(C)(C)C)C=C1 PIASNQAKAMXOQL-UHFFFAOYSA-N 0.000 claims 1
• BCHPDWOONRTFDM-UHFFFAOYSA-N 4-[5-[(4-tert-butylphenyl)methylsulfanyl]-4-methyl-1,2,4-triazol-3-yl]pyridine Chemical compound N=1N=C(C=2C=CN=CC=2)N(C)C=1SCC1=CC=C(C(C)(C)C)C=C1 BCHPDWOONRTFDM-UHFFFAOYSA-N 0.000 claims 1
• KHAXDXLAUXSRCH-UHFFFAOYSA-N 4-[5-[2-(2-methoxyphenoxy)ethylsulfanyl]-4-methyl-1,2,4-triazol-3-yl]aniline Chemical compound COC1=CC=CC=C1OCCSC(N1C)=NN=C1C1=CC=C(N)C=C1 KHAXDXLAUXSRCH-UHFFFAOYSA-N 0.000 claims 1
• NOABKXNZQOTPJK-UHFFFAOYSA-N 4-[[4-ethyl-5-(1H-indol-3-ylmethyl)-1,2,4-triazol-3-yl]sulfanylmethyl]benzonitrile Chemical compound CCN1C(CC=2C3=CC=CC=C3NC=2)=NN=C1SCC1=CC=C(C#N)C=C1 NOABKXNZQOTPJK-UHFFFAOYSA-N 0.000 claims 1
• HDERFIMDQYYBLQ-UHFFFAOYSA-N 4-[[4-ethyl-5-(2-phenoxyphenyl)-1,2,4-triazol-3-yl]sulfanylmethyl]benzonitrile Chemical compound N=1N=C(C=2C(=CC=CC=2)OC=2C=CC=CC=2)N(CC)C=1SCC1=CC=C(C#N)C=C1 HDERFIMDQYYBLQ-UHFFFAOYSA-N 0.000 claims 1
• RVZMUDIAQWZHRG-UHFFFAOYSA-N 4-[[4-ethyl-5-(3-hydroxypropyl)-1,2,4-triazol-3-yl]sulfanylmethyl]benzonitrile Chemical compound CCN1C(CCCO)=NN=C1SCC1=CC=C(C#N)C=C1 RVZMUDIAQWZHRG-UHFFFAOYSA-N 0.000 claims 1
• SBBLEUVFEHJPGB-UHFFFAOYSA-N 4-[[4-ethyl-5-(4-methoxyphenyl)-1,2,4-triazol-3-yl]sulfanylmethyl]benzonitrile Chemical compound N=1N=C(C=2C=CC(OC)=CC=2)N(CC)C=1SCC1=CC=C(C#N)C=C1 SBBLEUVFEHJPGB-UHFFFAOYSA-N 0.000 claims 1
• UPHYHHLLAZJYTM-UHFFFAOYSA-N 4-[[4-ethyl-5-(4-phenylthiadiazol-5-yl)-1,2,4-triazol-3-yl]sulfanylmethyl]benzonitrile Chemical compound N=1N=C(C2=C(N=NS2)C=2C=CC=CC=2)N(CC)C=1SCC1=CC=C(C#N)C=C1 UPHYHHLLAZJYTM-UHFFFAOYSA-N 0.000 claims 1
• JLIZTFPVKKSYSJ-UHFFFAOYSA-N 4-[[4-ethyl-5-(4-piperidin-1-ylsulfonylphenyl)-1,2,4-triazol-3-yl]sulfanylmethyl]benzonitrile Chemical compound N=1N=C(C=2C=CC(=CC=2)S(=O)(=O)N2CCCCC2)N(CC)C=1SCC1=CC=C(C#N)C=C1 JLIZTFPVKKSYSJ-UHFFFAOYSA-N 0.000 claims 1
• JSZBFKGBRBXERT-UHFFFAOYSA-N 4-[[4-ethyl-5-(5-methylthiophen-2-yl)-1,2,4-triazol-3-yl]sulfanylmethyl]benzonitrile Chemical compound N=1N=C(C=2SC(C)=CC=2)N(CC)C=1SCC1=CC=C(C#N)C=C1 JSZBFKGBRBXERT-UHFFFAOYSA-N 0.000 claims 1
• SYAXWOJTDAOUJC-UHFFFAOYSA-N 4-[[5-(1,3-benzodioxol-5-yl)-4-ethyl-1,2,4-triazol-3-yl]sulfanylmethyl]benzonitrile Chemical compound N=1N=C(C=2C=C3OCOC3=CC=2)N(CC)C=1SCC1=CC=C(C#N)C=C1 SYAXWOJTDAOUJC-UHFFFAOYSA-N 0.000 claims 1
• VLPOJEOUSGIMCG-UHFFFAOYSA-N 4-[[5-(1-benzothiophen-2-yl)-4-ethyl-1,2,4-triazol-3-yl]sulfanylmethyl]benzonitrile Chemical compound N=1N=C(C=2SC3=CC=CC=C3C=2)N(CC)C=1SCC1=CC=C(C#N)C=C1 VLPOJEOUSGIMCG-UHFFFAOYSA-N 0.000 claims 1
• GTXTWGFKYJZBJD-UHFFFAOYSA-N 4-[[5-(2-bromophenyl)-4-ethyl-1,2,4-triazol-3-yl]sulfanylmethyl]benzonitrile Chemical compound N=1N=C(C=2C(=CC=CC=2)Br)N(CC)C=1SCC1=CC=C(C#N)C=C1 GTXTWGFKYJZBJD-UHFFFAOYSA-N 0.000 claims 1
• WBSQKBVCMIVFIM-UHFFFAOYSA-N 4-[[5-(3,3,5-trimethyl-7-azabicyclo[3.2.1]octane-7-carbonyl)indol-1-yl]methyl]benzonitrile Chemical compound C1C(C)(C)CC(C)(C2)CC1N2C(=O)C(C=C1C=C2)=CC=C1N2CC1=CC=C(C#N)C=C1 WBSQKBVCMIVFIM-UHFFFAOYSA-N 0.000 claims 1
• AZDXADGHORPDIT-UHFFFAOYSA-N 4-[[5-(3-chloro-4-methylthiophen-2-yl)-4-ethyl-1,2,4-triazol-3-yl]sulfanylmethyl]benzonitrile Chemical compound N=1N=C(C2=C(C(C)=CS2)Cl)N(CC)C=1SCC1=CC=C(C#N)C=C1 AZDXADGHORPDIT-UHFFFAOYSA-N 0.000 claims 1
• KRBJECGCLMEFFZ-UHFFFAOYSA-N 4-[[5-(4-chlorophenyl)-4-ethyl-1,2,4-triazol-3-yl]sulfanylmethyl]benzonitrile Chemical compound N=1N=C(C=2C=CC(Cl)=CC=2)N(CC)C=1SCC1=CC=C(C#N)C=C1 KRBJECGCLMEFFZ-UHFFFAOYSA-N 0.000 claims 1
• NSBMTWPTPAUAKE-UHFFFAOYSA-N 4-[[5-(5-chlorothiophen-2-yl)-4-ethyl-1,2,4-triazol-3-yl]sulfanylmethyl]benzonitrile Chemical compound N=1N=C(C=2SC(Cl)=CC=2)N(CC)C=1SCC1=CC=C(C#N)C=C1 NSBMTWPTPAUAKE-UHFFFAOYSA-N 0.000 claims 1
• WWIXCWSAVMUZRS-UHFFFAOYSA-N 4-[[5-[4-(2,5-dimethylpyrrol-1-yl)phenyl]-4-ethyl-1,2,4-triazol-3-yl]sulfanylmethyl]benzonitrile Chemical compound N=1N=C(C=2C=CC(=CC=2)N2C(=CC=C2C)C)N(CC)C=1SCC1=CC=C(C#N)C=C1 WWIXCWSAVMUZRS-UHFFFAOYSA-N 0.000 claims 1
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• NJPRATJHCGOAKI-UHFFFAOYSA-N 4-amino-N-(2,3-dihydro-1H-inden-2-yl)-N-[(3-hydroxyphenyl)methyl]-2-(propanoylamino)butanamide Chemical compound C1C2=CC=CC=C2CC1N(C(=O)C(CCN)NC(=O)CC)CC1=CC=CC(O)=C1 NJPRATJHCGOAKI-UHFFFAOYSA-N 0.000 claims 1
• VBQURISEJZGIJF-UHFFFAOYSA-N 4-amino-N-cyclohexyl-N-methylbenzamide Chemical compound C=1C=C(N)C=CC=1C(=O)N(C)C1CCCCC1 VBQURISEJZGIJF-UHFFFAOYSA-N 0.000 claims 1
• KSMOEHJKKPNNLU-UHFFFAOYSA-N 4-benzoyl-N-methyl-N-phenylbenzamide Chemical compound C=1C=CC=CC=1N(C)C(=O)C(C=C1)=CC=C1C(=O)C1=CC=CC=C1 KSMOEHJKKPNNLU-UHFFFAOYSA-N 0.000 claims 1
• AUTMXVSOOABCRA-UHFFFAOYSA-N 4-benzyl-3,5-bis(4-methylphenyl)-1,2,4-triazole Chemical compound C1=CC(C)=CC=C1C(N1CC=2C=CC=CC=2)=NN=C1C1=CC=C(C)C=C1 AUTMXVSOOABCRA-UHFFFAOYSA-N 0.000 claims 1
• OMJCGOMLYOLCQK-UHFFFAOYSA-N 4-benzyl-3-[(4-fluoronaphthalen-1-yl)methylsulfanyl]-5-phenyl-1,2,4-triazole Chemical compound C12=CC=CC=C2C(F)=CC=C1CSC(N1CC=2C=CC=CC=2)=NN=C1C1=CC=CC=C1 OMJCGOMLYOLCQK-UHFFFAOYSA-N 0.000 claims 1
• XILSEGNRZUYELB-UHFFFAOYSA-N 4-benzyl-3-cyclohexyl-1H-1,2,4-triazole-5-thione Chemical compound C=1C=CC=CC=1CN1C(=S)NN=C1C1CCCCC1 XILSEGNRZUYELB-UHFFFAOYSA-N 0.000 claims 1
• RZGYDZODJLKUAS-UHFFFAOYSA-N 4-bromo-1-ethyl-N-(2-methylsulfanylphenyl)pyrazole-3-carboxamide Chemical compound CCN1C=C(Br)C(C(=O)NC=2C(=CC=CC=2)SC)=N1 RZGYDZODJLKUAS-UHFFFAOYSA-N 0.000 claims 1
• SOOIJPNTAQSLKT-UHFFFAOYSA-N 4-bromo-N-[3-(piperidine-1-carbonyl)phenyl]benzamide Chemical compound C1=CC(Br)=CC=C1C(=O)NC1=CC=CC(C(=O)N2CCCCC2)=C1 SOOIJPNTAQSLKT-UHFFFAOYSA-N 0.000 claims 1
• UZZVSLCBVYKWJP-UHFFFAOYSA-N 4-butyl-3-(3-chlorophenyl)-1H-1,2,4-triazole-5-thione Chemical compound CCCCN1C(S)=NN=C1C1=CC=CC(Cl)=C1 UZZVSLCBVYKWJP-UHFFFAOYSA-N 0.000 claims 1
• PPOIDZGFAOGDMF-UHFFFAOYSA-N 4-chloro-N-(4,7,7-trimethyl-3-bicyclo[2.2.1]heptanyl)benzamide Chemical compound CC1(C)C(C2)CCC1(C)C2NC(=O)C1=CC=C(Cl)C=C1 PPOIDZGFAOGDMF-UHFFFAOYSA-N 0.000 claims 1
• LIXSCNLHIZAPAQ-UHFFFAOYSA-N 4-chloro-N-[3-methyl-1-oxo-1-(3,3,5-trimethyl-7-azabicyclo[3.2.1]octan-7-yl)pentan-2-yl]benzamide Chemical compound C1C(CC(C)(C)C2)(C)CC2N1C(=O)C(C(C)CC)NC(=O)C1=CC=C(Cl)C=C1 LIXSCNLHIZAPAQ-UHFFFAOYSA-N 0.000 claims 1
• DSEGTCSERAIXAT-UHFFFAOYSA-N 4-chloro-N-cyclohexyl-N-ethyl-3-nitrobenzamide Chemical compound C=1C=C(Cl)C([N+]([O-])=O)=CC=1C(=O)N(CC)C1CCCCC1 DSEGTCSERAIXAT-UHFFFAOYSA-N 0.000 claims 1
• 125000006283 4-chlorobenzyl group Chemical group [H]C1=C([H])C(=C([H])C([H])=C1Cl)C([H])([H])* 0.000 claims 1
• ODZPQBCHGIRTHD-UHFFFAOYSA-N 4-cyclopropyl-3-(2-methoxyethylsulfanyl)-5-(2-methoxyphenyl)-1,2,4-triazole Chemical compound C1CC1N1C(SCCOC)=NN=C1C1=CC=CC=C1OC ODZPQBCHGIRTHD-UHFFFAOYSA-N 0.000 claims 1
• AOUOKAHXWSRPEE-UHFFFAOYSA-N 4-cyclopropyl-3-(2-methoxyethylsulfanyl)-5-thiophen-2-yl-1,2,4-triazole Chemical compound C1CC1N1C(SCCOC)=NN=C1C1=CC=CS1 AOUOKAHXWSRPEE-UHFFFAOYSA-N 0.000 claims 1
• CTPUECQCTXSBMM-UHFFFAOYSA-N 4-ethyl-3-(2-methoxyphenyl)-5-[(2-nitrophenyl)methylsulfanyl]-1,2,4-triazole Chemical compound N=1N=C(C=2C(=CC=CC=2)OC)N(CC)C=1SCC1=CC=CC=C1[N+]([O-])=O CTPUECQCTXSBMM-UHFFFAOYSA-N 0.000 claims 1
• REBPSPZTHZRFQR-UHFFFAOYSA-N 4-ethyl-3-(2-methoxyphenyl)-5-[(4-methylphenyl)methylsulfanyl]-1,2,4-triazole Chemical compound N=1N=C(C=2C(=CC=CC=2)OC)N(CC)C=1SCC1=CC=C(C)C=C1 REBPSPZTHZRFQR-UHFFFAOYSA-N 0.000 claims 1
• ZAFFZYIXKBDCHO-UHFFFAOYSA-N 4-ethyl-3-(2-methoxyphenyl)-5-[(4-methylsulfonylphenyl)methylsulfanyl]-1,2,4-triazole Chemical compound N=1N=C(C=2C(=CC=CC=2)OC)N(CC)C=1SCC1=CC=C(S(C)(=O)=O)C=C1 ZAFFZYIXKBDCHO-UHFFFAOYSA-N 0.000 claims 1
• GSIDREWZVJVEIF-UHFFFAOYSA-N 4-ethyl-3-(2-methoxyphenyl)-5-[(4-nitrophenyl)methylsulfanyl]-1,2,4-triazole Chemical compound N=1N=C(C=2C(=CC=CC=2)OC)N(CC)C=1SCC1=CC=C([N+]([O-])=O)C=C1 GSIDREWZVJVEIF-UHFFFAOYSA-N 0.000 claims 1
• ARBASIDAVPCJHA-UHFFFAOYSA-N 4-ethyl-3-(2-methoxyphenyl)-5-[(4-phenylmethoxyphenyl)methylsulfanyl]-1,2,4-triazole Chemical compound N=1N=C(C=2C(=CC=CC=2)OC)N(CC)C=1SCC(C=C1)=CC=C1OCC1=CC=CC=C1 ARBASIDAVPCJHA-UHFFFAOYSA-N 0.000 claims 1
• GXPGRBWFHBQUCF-UHFFFAOYSA-N 4-ethyl-3-(2-methoxyphenyl)-5-[(5-methyl-2-nitrophenyl)methylsulfanyl]-1,2,4-triazole Chemical compound N=1N=C(C=2C(=CC=CC=2)OC)N(CC)C=1SCC1=CC(C)=CC=C1[N+]([O-])=O GXPGRBWFHBQUCF-UHFFFAOYSA-N 0.000 claims 1
• XOMILXVIANENOJ-UHFFFAOYSA-N 4-ethyl-3-(2-methoxyphenyl)-5-[[3-(trifluoromethoxy)phenyl]methylsulfanyl]-1,2,4-triazole Chemical compound N=1N=C(C=2C(=CC=CC=2)OC)N(CC)C=1SCC1=CC=CC(OC(F)(F)F)=C1 XOMILXVIANENOJ-UHFFFAOYSA-N 0.000 claims 1
• HEFFRPZKFLKGKN-UHFFFAOYSA-N 4-ethyl-3-(2-methoxyphenyl)-5-[[4-(trifluoromethoxy)phenyl]methylsulfanyl]-1,2,4-triazole Chemical compound N=1N=C(C=2C(=CC=CC=2)OC)N(CC)C=1SCC1=CC=C(OC(F)(F)F)C=C1 HEFFRPZKFLKGKN-UHFFFAOYSA-N 0.000 claims 1
• TXVIAEAZRHFPSD-UHFFFAOYSA-N 4-ethyl-3-(2-methoxyphenyl)-5-[[4-(trifluoromethyl)phenyl]methylsulfanyl]-1,2,4-triazole Chemical compound N=1N=C(C=2C(=CC=CC=2)OC)N(CC)C=1SCC1=CC=C(C(F)(F)F)C=C1 TXVIAEAZRHFPSD-UHFFFAOYSA-N 0.000 claims 1
• FSZZUCJWZZZGGB-UHFFFAOYSA-N 4-ethyl-3-(2-phenoxyphenyl)-5-[(4-phenylmethoxyphenyl)methylsulfanyl]-1,2,4-triazole Chemical compound N=1N=C(C=2C(=CC=CC=2)OC=2C=CC=CC=2)N(CC)C=1SCC(C=C1)=CC=C1OCC1=CC=CC=C1 FSZZUCJWZZZGGB-UHFFFAOYSA-N 0.000 claims 1
• FGNZSUZIPBNIIH-UHFFFAOYSA-N 4-ethyl-3-(2-phenoxyphenyl)-5-[[3-(trifluoromethoxy)phenyl]methylsulfanyl]-1,2,4-triazole Chemical compound N=1N=C(C=2C(=CC=CC=2)OC=2C=CC=CC=2)N(CC)C=1SCC1=CC=CC(OC(F)(F)F)=C1 FGNZSUZIPBNIIH-UHFFFAOYSA-N 0.000 claims 1
• PQEYJSXHIFZQHI-UHFFFAOYSA-N 4-ethyl-3-(2-phenoxyphenyl)-5-[[4-(trifluoromethyl)phenyl]methylsulfanyl]-1,2,4-triazole Chemical compound N=1N=C(C=2C(=CC=CC=2)OC=2C=CC=CC=2)N(CC)C=1SCC1=CC=C(C(F)(F)F)C=C1 PQEYJSXHIFZQHI-UHFFFAOYSA-N 0.000 claims 1
• CKBYENMOKAIAPX-UHFFFAOYSA-N 4-ethyl-3-(4-methoxyphenyl)-5-[(2-nitrophenyl)methylsulfanyl]-1,2,4-triazole Chemical compound N=1N=C(C=2C=CC(OC)=CC=2)N(CC)C=1SCC1=CC=CC=C1[N+]([O-])=O CKBYENMOKAIAPX-UHFFFAOYSA-N 0.000 claims 1
• XESYVWOXHFYGJS-UHFFFAOYSA-N 4-ethyl-3-(4-methoxyphenyl)-5-[(4-methoxyphenyl)methylsulfanyl]-1,2,4-triazole Chemical compound N=1N=C(C=2C=CC(OC)=CC=2)N(CC)C=1SCC1=CC=C(OC)C=C1 XESYVWOXHFYGJS-UHFFFAOYSA-N 0.000 claims 1
• JNQQUNKQHQTCCT-UHFFFAOYSA-N 4-ethyl-3-(4-methoxyphenyl)-5-[(4-methylsulfonylphenyl)methylsulfanyl]-1,2,4-triazole Chemical compound N=1N=C(C=2C=CC(OC)=CC=2)N(CC)C=1SCC1=CC=C(S(C)(=O)=O)C=C1 JNQQUNKQHQTCCT-UHFFFAOYSA-N 0.000 claims 1
• WYYGCPZFPLRJLX-UHFFFAOYSA-N 4-ethyl-3-(4-methoxyphenyl)-5-[(4-phenylmethoxyphenyl)methylsulfanyl]-1,2,4-triazole Chemical compound N=1N=C(C=2C=CC(OC)=CC=2)N(CC)C=1SCC(C=C1)=CC=C1OCC1=CC=CC=C1 WYYGCPZFPLRJLX-UHFFFAOYSA-N 0.000 claims 1
• NCBBFMBQKVBQMZ-UHFFFAOYSA-N 4-ethyl-3-(4-methoxyphenyl)-5-[[3-(trifluoromethoxy)phenyl]methylsulfanyl]-1,2,4-triazole Chemical compound N=1N=C(C=2C=CC(OC)=CC=2)N(CC)C=1SCC1=CC=CC(OC(F)(F)F)=C1 NCBBFMBQKVBQMZ-UHFFFAOYSA-N 0.000 claims 1
• WNHUSXQMCUNCQY-UHFFFAOYSA-N 4-ethyl-3-(4-methoxyphenyl)-5-[[4-(trifluoromethyl)phenyl]methylsulfanyl]-1,2,4-triazole Chemical compound N=1N=C(C=2C=CC(OC)=CC=2)N(CC)C=1SCC1=CC=C(C(F)(F)F)C=C1 WNHUSXQMCUNCQY-UHFFFAOYSA-N 0.000 claims 1
• VQIFYRTWGIWQEE-UHFFFAOYSA-N 4-ethyl-3-(5-methylthiophen-2-yl)-5-[(2-nitrophenyl)methylsulfanyl]-1,2,4-triazole Chemical compound N=1N=C(C=2SC(C)=CC=2)N(CC)C=1SCC1=CC=CC=C1[N+]([O-])=O VQIFYRTWGIWQEE-UHFFFAOYSA-N 0.000 claims 1
• ARIBLEKFHQWSJO-UHFFFAOYSA-N 4-ethyl-3-(5-methylthiophen-2-yl)-5-[(3-nitrophenyl)methylsulfanyl]-1,2,4-triazole Chemical compound N=1N=C(C=2SC(C)=CC=2)N(CC)C=1SCC1=CC=CC([N+]([O-])=O)=C1 ARIBLEKFHQWSJO-UHFFFAOYSA-N 0.000 claims 1
• ODGMVQORVYJCPO-UHFFFAOYSA-N 4-ethyl-3-(5-methylthiophen-2-yl)-5-[(4-nitrophenyl)methylsulfanyl]-1,2,4-triazole Chemical compound N=1N=C(C=2SC(C)=CC=2)N(CC)C=1SCC1=CC=C([N+]([O-])=O)C=C1 ODGMVQORVYJCPO-UHFFFAOYSA-N 0.000 claims 1
• NJYUCKYVUWCUPX-UHFFFAOYSA-N 4-ethyl-3-(5-methylthiophen-2-yl)-5-[[4-(trifluoromethoxy)phenyl]methylsulfanyl]-1,2,4-triazole Chemical compound N=1N=C(C=2SC(C)=CC=2)N(CC)C=1SCC1=CC=C(OC(F)(F)F)C=C1 NJYUCKYVUWCUPX-UHFFFAOYSA-N 0.000 claims 1
• PORJHQAGLXRDTL-UHFFFAOYSA-N 4-ethyl-3-(5-methylthiophen-2-yl)-5-[[4-(trifluoromethyl)phenyl]methylsulfanyl]-1,2,4-triazole Chemical compound N=1N=C(C=2SC(C)=CC=2)N(CC)C=1SCC1=CC=C(C(F)(F)F)C=C1 PORJHQAGLXRDTL-UHFFFAOYSA-N 0.000 claims 1
• FCWOFTAAJAMCSV-UHFFFAOYSA-N 4-ethyl-3-[(2-nitrophenyl)methylsulfanyl]-5-(2-phenoxyphenyl)-1,2,4-triazole Chemical compound N=1N=C(C=2C(=CC=CC=2)OC=2C=CC=CC=2)N(CC)C=1SCC1=CC=CC=C1[N+]([O-])=O FCWOFTAAJAMCSV-UHFFFAOYSA-N 0.000 claims 1
• IGCCKFJXTSOYOC-UHFFFAOYSA-N 4-ethyl-3-[(2-nitrophenyl)methylsulfanyl]-5-[1-phenyl-5-(trifluoromethyl)pyrazol-4-yl]-1,2,4-triazole Chemical compound N=1N=C(C2=C(N(N=C2)C=2C=CC=CC=2)C(F)(F)F)N(CC)C=1SCC1=CC=CC=C1[N+]([O-])=O IGCCKFJXTSOYOC-UHFFFAOYSA-N 0.000 claims 1
• ZTEWMOVFUTVCQW-UHFFFAOYSA-N 4-ethyl-3-[(3-nitrophenyl)methylsulfanyl]-5-[1-phenyl-5-(trifluoromethyl)pyrazol-4-yl]-1,2,4-triazole Chemical compound N=1N=C(C2=C(N(N=C2)C=2C=CC=CC=2)C(F)(F)F)N(CC)C=1SCC1=CC=CC([N+]([O-])=O)=C1 ZTEWMOVFUTVCQW-UHFFFAOYSA-N 0.000 claims 1
• XIBOJQFSTHLSIN-UHFFFAOYSA-N 4-ethyl-3-[(4-methoxyphenyl)methylsulfanyl]-5-(2-phenoxyphenyl)-1,2,4-triazole Chemical compound N=1N=C(C=2C(=CC=CC=2)OC=2C=CC=CC=2)N(CC)C=1SCC1=CC=C(OC)C=C1 XIBOJQFSTHLSIN-UHFFFAOYSA-N 0.000 claims 1
• LRPBBFNCFVEOPV-UHFFFAOYSA-N 4-ethyl-3-[(4-methoxyphenyl)methylsulfanyl]-5-(5-methylthiophen-2-yl)-1,2,4-triazole Chemical compound N=1N=C(C=2SC(C)=CC=2)N(CC)C=1SCC1=CC=C(OC)C=C1 LRPBBFNCFVEOPV-UHFFFAOYSA-N 0.000 claims 1
• ULZOWEVPJIIBKR-UHFFFAOYSA-N 4-ethyl-3-[(4-methoxyphenyl)methylsulfanyl]-5-naphthalen-1-yl-1,2,4-triazole Chemical compound N=1N=C(C=2C3=CC=CC=C3C=CC=2)N(CC)C=1SCC1=CC=C(OC)C=C1 ULZOWEVPJIIBKR-UHFFFAOYSA-N 0.000 claims 1
• WNJFIVGBJDQDSS-UHFFFAOYSA-N 4-ethyl-3-[(4-methoxyphenyl)methylsulfanyl]-5-thiophen-2-yl-1,2,4-triazole Chemical compound N=1N=C(C=2SC=CC=2)N(CC)C=1SCC1=CC=C(OC)C=C1 WNJFIVGBJDQDSS-UHFFFAOYSA-N 0.000 claims 1
• IBBGLODAOHHFMO-UHFFFAOYSA-N 4-ethyl-3-[(4-methylphenyl)methylsulfanyl]-5-(2-phenoxyphenyl)-1,2,4-triazole Chemical compound N=1N=C(C=2C(=CC=CC=2)OC=2C=CC=CC=2)N(CC)C=1SCC1=CC=C(C)C=C1 IBBGLODAOHHFMO-UHFFFAOYSA-N 0.000 claims 1
• UHKOIOLBKJKVQD-UHFFFAOYSA-N 4-ethyl-3-[(4-methylphenyl)methylsulfanyl]-5-(4-nitrophenyl)-1,2,4-triazole Chemical compound N=1N=C(C=2C=CC(=CC=2)[N+]([O-])=O)N(CC)C=1SCC1=CC=C(C)C=C1 UHKOIOLBKJKVQD-UHFFFAOYSA-N 0.000 claims 1
• NHTLTXJUEMHAMF-UHFFFAOYSA-N 4-ethyl-3-[(4-methylphenyl)methylsulfanyl]-5-(5-methylthiophen-2-yl)-1,2,4-triazole Chemical compound N=1N=C(C=2SC(C)=CC=2)N(CC)C=1SCC1=CC=C(C)C=C1 NHTLTXJUEMHAMF-UHFFFAOYSA-N 0.000 claims 1
• AOSMUGPYCRQJDB-UHFFFAOYSA-N 4-ethyl-3-[(4-methylphenyl)methylsulfanyl]-5-[1-phenyl-5-(trifluoromethyl)pyrazol-4-yl]-1,2,4-triazole Chemical compound N=1N=C(C2=C(N(N=C2)C=2C=CC=CC=2)C(F)(F)F)N(CC)C=1SCC1=CC=C(C)C=C1 AOSMUGPYCRQJDB-UHFFFAOYSA-N 0.000 claims 1
• JDORSLUONBPTFH-UHFFFAOYSA-N 4-ethyl-3-[(4-methylphenyl)methylsulfanyl]-5-naphthalen-1-yl-1,2,4-triazole Chemical compound N=1N=C(C=2C3=CC=CC=C3C=CC=2)N(CC)C=1SCC1=CC=C(C)C=C1 JDORSLUONBPTFH-UHFFFAOYSA-N 0.000 claims 1
• FVIGYVNFOJVLCQ-UHFFFAOYSA-N 4-ethyl-3-[(4-methylphenyl)methylsulfanyl]-5-thiophen-2-yl-1,2,4-triazole Chemical compound N=1N=C(C=2SC=CC=2)N(CC)C=1SCC1=CC=C(C)C=C1 FVIGYVNFOJVLCQ-UHFFFAOYSA-N 0.000 claims 1
• PMHYXCRFZGYKLU-UHFFFAOYSA-N 4-ethyl-3-[(4-methylsulfonylphenyl)methylsulfanyl]-5-(2-phenoxyphenyl)-1,2,4-triazole Chemical compound N=1N=C(C=2C(=CC=CC=2)OC=2C=CC=CC=2)N(CC)C=1SCC1=CC=C(S(C)(=O)=O)C=C1 PMHYXCRFZGYKLU-UHFFFAOYSA-N 0.000 claims 1
• ZDNNSVQKWQFUCM-UHFFFAOYSA-N 4-ethyl-3-[(4-methylsulfonylphenyl)methylsulfanyl]-5-(5-methylthiophen-2-yl)-1,2,4-triazole Chemical compound N=1N=C(C=2SC(C)=CC=2)N(CC)C=1SCC1=CC=C(S(C)(=O)=O)C=C1 ZDNNSVQKWQFUCM-UHFFFAOYSA-N 0.000 claims 1
• OIFDZFISYKRABH-UHFFFAOYSA-N 4-ethyl-3-[(4-methylsulfonylphenyl)methylsulfanyl]-5-[1-phenyl-5-(trifluoromethyl)pyrazol-4-yl]-1,2,4-triazole Chemical compound N=1N=C(C2=C(N(N=C2)C=2C=CC=CC=2)C(F)(F)F)N(CC)C=1SCC1=CC=C(S(C)(=O)=O)C=C1 OIFDZFISYKRABH-UHFFFAOYSA-N 0.000 claims 1
• PBLTXWMLGMDBTA-UHFFFAOYSA-N 4-ethyl-3-[(4-methylsulfonylphenyl)methylsulfanyl]-5-naphthalen-1-yl-1,2,4-triazole Chemical compound N=1N=C(C=2C3=CC=CC=C3C=CC=2)N(CC)C=1SCC1=CC=C(S(C)(=O)=O)C=C1 PBLTXWMLGMDBTA-UHFFFAOYSA-N 0.000 claims 1
• HAZPMUOTNFHHPN-UHFFFAOYSA-N 4-ethyl-3-[(4-methylsulfonylphenyl)methylsulfanyl]-5-thiophen-2-yl-1,2,4-triazole Chemical compound N=1N=C(C=2SC=CC=2)N(CC)C=1SCC1=CC=C(S(C)(=O)=O)C=C1 HAZPMUOTNFHHPN-UHFFFAOYSA-N 0.000 claims 1
• ZZYCPGBATIITLA-UHFFFAOYSA-N 4-ethyl-3-[(4-nitrophenyl)methylsulfanyl]-5-thiophen-2-yl-1,2,4-triazole Chemical compound N=1N=C(C=2SC=CC=2)N(CC)C=1SCC1=CC=C([N+]([O-])=O)C=C1 ZZYCPGBATIITLA-UHFFFAOYSA-N 0.000 claims 1
• FZOXXTPVJJDGQB-UHFFFAOYSA-N 4-ethyl-3-[(4-phenylmethoxyphenyl)methylsulfanyl]-5-[1-phenyl-5-(trifluoromethyl)pyrazol-4-yl]-1,2,4-triazole Chemical compound N=1N=C(C2=C(N(N=C2)C=2C=CC=CC=2)C(F)(F)F)N(CC)C=1SCC(C=C1)=CC=C1OCC1=CC=CC=C1 FZOXXTPVJJDGQB-UHFFFAOYSA-N 0.000 claims 1
• RFTUEJYMHAZVLE-UHFFFAOYSA-N 4-ethyl-3-[(5-methyl-2-nitrophenyl)methylsulfanyl]-5-[1-phenyl-5-(trifluoromethyl)pyrazol-4-yl]-1,2,4-triazole Chemical compound N=1N=C(C2=C(N(N=C2)C=2C=CC=CC=2)C(F)(F)F)N(CC)C=1SCC1=CC(C)=CC=C1[N+]([O-])=O RFTUEJYMHAZVLE-UHFFFAOYSA-N 0.000 claims 1
• NPOYIHYSCDSVPU-UHFFFAOYSA-N 4-ethyl-3-[(5-methyl-2-nitrophenyl)methylsulfanyl]-5-naphthalen-1-yl-1,2,4-triazole Chemical compound N=1N=C(C=2C3=CC=CC=C3C=CC=2)N(CC)C=1SCC1=CC(C)=CC=C1[N+]([O-])=O NPOYIHYSCDSVPU-UHFFFAOYSA-N 0.000 claims 1
• ONTBBQIOQCFBHH-UHFFFAOYSA-N 4-ethyl-3-[(5-methyl-2-nitrophenyl)methylsulfanyl]-5-thiophen-2-yl-1,2,4-triazole Chemical compound N=1N=C(C=2SC=CC=2)N(CC)C=1SCC1=CC(C)=CC=C1[N+]([O-])=O ONTBBQIOQCFBHH-UHFFFAOYSA-N 0.000 claims 1
• HZGSVZSAEVNTCU-UHFFFAOYSA-N 4-ethyl-3-[1-phenyl-5-(trifluoromethyl)pyrazol-4-yl]-5-[[4-(trifluoromethoxy)phenyl]methylsulfanyl]-1,2,4-triazole Chemical compound N=1N=C(C2=C(N(N=C2)C=2C=CC=CC=2)C(F)(F)F)N(CC)C=1SCC1=CC=C(OC(F)(F)F)C=C1 HZGSVZSAEVNTCU-UHFFFAOYSA-N 0.000 claims 1
• WQMYUIWCKGPMOD-UHFFFAOYSA-N 4-ethyl-3-naphthalen-1-yl-5-[(3-nitrophenyl)methylsulfanyl]-1,2,4-triazole Chemical compound N=1N=C(C=2C3=CC=CC=C3C=CC=2)N(CC)C=1SCC1=CC=CC([N+]([O-])=O)=C1 WQMYUIWCKGPMOD-UHFFFAOYSA-N 0.000 claims 1
• WPMNOAFWIAOCDI-UHFFFAOYSA-N 4-ethyl-3-naphthalen-1-yl-5-[(4-nitrophenyl)methylsulfanyl]-1,2,4-triazole Chemical compound N=1N=C(C=2C3=CC=CC=C3C=CC=2)N(CC)C=1SCC1=CC=C([N+]([O-])=O)C=C1 WPMNOAFWIAOCDI-UHFFFAOYSA-N 0.000 claims 1
• AFSZDIIOIYCDPL-UHFFFAOYSA-N 4-ethyl-3-naphthalen-1-yl-5-[[4-(trifluoromethyl)phenyl]methylsulfanyl]-1,2,4-triazole Chemical compound N=1N=C(C=2C3=CC=CC=C3C=CC=2)N(CC)C=1SCC1=CC=C(C(F)(F)F)C=C1 AFSZDIIOIYCDPL-UHFFFAOYSA-N 0.000 claims 1
• WVOCXAPOSDDJDD-UHFFFAOYSA-N 4-ethyl-3-thiophen-2-yl-5-[[4-(trifluoromethoxy)phenyl]methylsulfanyl]-1,2,4-triazole Chemical compound N=1N=C(C=2SC=CC=2)N(CC)C=1SCC1=CC=C(OC(F)(F)F)C=C1 WVOCXAPOSDDJDD-UHFFFAOYSA-N 0.000 claims 1
• MODKOYXFRWMZAF-UHFFFAOYSA-N 4-ethyl-3-thiophen-2-yl-5-[[4-(trifluoromethyl)phenyl]methylsulfanyl]-1,2,4-triazole Chemical compound N=1N=C(C=2SC=CC=2)N(CC)C=1SCC1=CC=C(C(F)(F)F)C=C1 MODKOYXFRWMZAF-UHFFFAOYSA-N 0.000 claims 1
• JGFVAUUDLCHKQI-UHFFFAOYSA-N 4-hydroxy-N-[(4-hydroxyphenyl)methyl]-N-(2-methylpropyl)benzamide Chemical compound C=1C=C(O)C=CC=1C(=O)N(CC(C)C)CC1=CC=C(O)C=C1 JGFVAUUDLCHKQI-UHFFFAOYSA-N 0.000 claims 1
• ZDTDRQKMYDIBCL-UHFFFAOYSA-N 4-methyl-3-(4-methylphenyl)-5-(2-phenylethylsulfanyl)-1,2,4-triazole Chemical compound C1=CC(C)=CC=C1C(N1C)=NN=C1SCCC1=CC=CC=C1 ZDTDRQKMYDIBCL-UHFFFAOYSA-N 0.000 claims 1
• VJTNNIOWMBZUGK-UHFFFAOYSA-N 4-methyl-3-[(2-methylphenyl)methylsulfanyl]-5-thiophen-2-yl-1,2,4-triazole Chemical compound CC1=CC=CC=C1CSC(N1C)=NN=C1C1=CC=CS1 VJTNNIOWMBZUGK-UHFFFAOYSA-N 0.000 claims 1
• SFMXKNDDMRQDNZ-UHFFFAOYSA-N 4-methyl-3-[(4-methylphenyl)methylsulfanyl]-5-[3-(trifluoromethyl)phenyl]-1,2,4-triazole Chemical compound C1=CC(C)=CC=C1CSC(N1C)=NN=C1C1=CC=CC(C(F)(F)F)=C1 SFMXKNDDMRQDNZ-UHFFFAOYSA-N 0.000 claims 1
• YSWSUZCEBFYVND-UHFFFAOYSA-N 4-methyl-3-[(4-nitrophenyl)methylsulfanyl]-5-phenyl-1,2,4-triazole Chemical compound N=1N=C(C=2C=CC=CC=2)N(C)C=1SCC1=CC=C([N+]([O-])=O)C=C1 YSWSUZCEBFYVND-UHFFFAOYSA-N 0.000 claims 1
• HVACUGYQMUTBDJ-UHFFFAOYSA-N 4-methyl-3-[3-[(4-methylphenyl)methoxy]thiophen-2-yl]-5-methylsulfanyl-1,2,4-triazole Chemical compound CN1C(SC)=NN=C1C1=C(OCC=2C=CC(C)=CC=2)C=CS1 HVACUGYQMUTBDJ-UHFFFAOYSA-N 0.000 claims 1
• JGPSODNQURDKFU-UHFFFAOYSA-N 4-methyl-3-[3-[[3-(trifluoromethyl)phenyl]methoxy]thiophen-2-yl]-1H-1,2,4-triazole-5-thione Chemical compound N1C(=S)N(C)C(C2=C(C=CS2)OCC=2C=C(C=CC=2)C(F)(F)F)=N1 JGPSODNQURDKFU-UHFFFAOYSA-N 0.000 claims 1
• BTMDFZSYLBTEOT-UHFFFAOYSA-N 4-methyl-3-methylsulfanyl-5-[3-[[3-(trifluoromethyl)phenyl]methoxy]thiophen-2-yl]-1,2,4-triazole Chemical compound CN1C(SC)=NN=C1C1=C(OCC=2C=C(C=CC=2)C(F)(F)F)C=CS1 BTMDFZSYLBTEOT-UHFFFAOYSA-N 0.000 claims 1
• IJOYYGFIORIFJG-UHFFFAOYSA-N 4-methyl-5-(4-methyl-5-prop-2-ynylsulfanyl-1,2,4-triazol-3-yl)-2-phenyl-1,3-thiazole Chemical compound CC=1N=C(C=2C=CC=CC=2)SC=1C1=NN=C(SCC#C)N1C IJOYYGFIORIFJG-UHFFFAOYSA-N 0.000 claims 1
• WBRQXZXOGRAPJI-UHFFFAOYSA-N 4-methyl-N-[2-(phenoxazine-10-carbonyl)phenyl]benzenesulfonamide Chemical compound C1=CC(C)=CC=C1S(=O)(=O)NC1=CC=CC=C1C(=O)N1C2=CC=CC=C2OC2=CC=CC=C21 WBRQXZXOGRAPJI-UHFFFAOYSA-N 0.000 claims 1
• AFPFMPNSJWQYPJ-UHFFFAOYSA-N 4-methyl-N-[3-methyl-1-oxo-1-(3,3,5-trimethyl-7-azabicyclo[3.2.1]octan-7-yl)pentan-2-yl]benzamide Chemical compound C1C(CC(C)(C)C2)(C)CC2N1C(=O)C(C(C)CC)NC(=O)C1=CC=C(C)C=C1 AFPFMPNSJWQYPJ-UHFFFAOYSA-N 0.000 claims 1
• NWEAQWFUCTVJDI-UHFFFAOYSA-N 4-methyl-N-naphthalen-1-yl-2-phenyl-1,3-thiazole-5-carboxamide Chemical compound S1C(C(=O)NC=2C3=CC=CC=C3C=CC=2)=C(C)N=C1C1=CC=CC=C1 NWEAQWFUCTVJDI-UHFFFAOYSA-N 0.000 claims 1
• LHNSBIUPQDSYIO-UHFFFAOYSA-N 4-tert-butyl-N-cyclooctylbenzamide Chemical compound C1=CC(C(C)(C)C)=CC=C1C(=O)NC1CCCCCCC1 LHNSBIUPQDSYIO-UHFFFAOYSA-N 0.000 claims 1
• UMCSDNAWBPUNIJ-UHFFFAOYSA-N 5,5-dimethyl-3-(3,4,5-trimethoxyphenyl)-6H-[1,2,4]triazolo[3,4-a]isoquinoline Chemical compound COC1=C(OC)C(OC)=CC(C=2N3C(C)(C)CC4=CC=CC=C4C3=NN=2)=C1 UMCSDNAWBPUNIJ-UHFFFAOYSA-N 0.000 claims 1
• LFESZQRDPUZMOE-UHFFFAOYSA-N 5,5-dimethyl-3-(4-methylphenyl)-6H-[1,2,4]triazolo[3,4-a]isoquinoline Chemical compound C1=CC(C)=CC=C1C1=NN=C2N1C(C)(C)CC1=CC=CC=C12 LFESZQRDPUZMOE-UHFFFAOYSA-N 0.000 claims 1
• CSCOJYVCYSWDLT-UHFFFAOYSA-N 5,5-dimethyl-3-phenyl-6H-[1,2,4]triazolo[3,4-a]isoquinoline Chemical compound N12C(C)(C)CC3=CC=CC=C3C2=NN=C1C1=CC=CC=C1 CSCOJYVCYSWDLT-UHFFFAOYSA-N 0.000 claims 1
• VEGAUVGGWIDIBY-UHFFFAOYSA-N 5,6-dihydrobenzo[b][1]benzazepin-11-yl-(2-methoxyphenyl)methanone Chemical compound COC1=CC=CC=C1C(=O)N1C2=CC=CC=C2CCC2=CC=CC=C21 VEGAUVGGWIDIBY-UHFFFAOYSA-N 0.000 claims 1
• ARVNJCBUCQXYTF-UHFFFAOYSA-N 5,6-dihydrobenzo[b][1]benzazepin-11-yl-(4-fluorophenyl)methanone Chemical compound C1=CC(F)=CC=C1C(=O)N1C2=CC=CC=C2CCC2=CC=CC=C21 ARVNJCBUCQXYTF-UHFFFAOYSA-N 0.000 claims 1
• KLWVLLPTXFKYLW-UHFFFAOYSA-N 5-(2,6-dichlorophenyl)sulfanyl-N-(naphthalen-1-ylmethyl)pentanamide Chemical compound ClC1=CC=CC(Cl)=C1SCCCCC(=O)NCC1=CC=CC2=CC=CC=C12 KLWVLLPTXFKYLW-UHFFFAOYSA-N 0.000 claims 1
• OADYUHNMWNRALE-UHFFFAOYSA-N 5-(2,6-dichlorophenyl)sulfanyl-N-[2-[3-(trifluoromethyl)phenyl]ethyl]pentanamide Chemical compound FC(F)(F)C1=CC=CC(CCNC(=O)CCCCSC=2C(=CC=CC=2Cl)Cl)=C1 OADYUHNMWNRALE-UHFFFAOYSA-N 0.000 claims 1
• IGJLEHOJTAUBNS-UHFFFAOYSA-N 5-(3,3,5-trimethyl-7-azabicyclo[3.2.1]octane-7-carbonyl)-1H-indole-3-carbonitrile Chemical compound C1=C2NC=C(C#N)C2=CC(C(=O)N2C3CC(CC(C)(C)C3)(C2)C)=C1 IGJLEHOJTAUBNS-UHFFFAOYSA-N 0.000 claims 1
• ZDJHUNUKBMLIHG-UHFFFAOYSA-N 5-(3,4-dimethoxyphenyl)-N-[(1,3-dimethylpyrazol-4-yl)methyl]-N-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide Chemical compound C1=C(OC)C(OC)=CC=C1C1=NC2=CC(C(=O)N(C)CC=3C(=NN(C)C=3)C)=NN2C(C(F)(F)F)=C1 ZDJHUNUKBMLIHG-UHFFFAOYSA-N 0.000 claims 1
• RMDCDDMQIQXVPW-UHFFFAOYSA-N 5-(5-benzylsulfanyl-4-ethyl-1,2,4-triazol-3-yl)-4-methylthiadiazole Chemical compound N=1N=C(C2=C(N=NS2)C)N(CC)C=1SCC1=CC=CC=C1 RMDCDDMQIQXVPW-UHFFFAOYSA-N 0.000 claims 1
• IZYULJPASQYGFY-UHFFFAOYSA-N 5-(furan-2-yl)-N-methyl-7-(trifluoromethyl)-N-[(1,3,5-trimethylpyrazol-4-yl)methyl]pyrazolo[1,5-a]pyrimidine-2-carboxamide Chemical compound C1=C2N=C(C=3OC=CC=3)C=C(C(F)(F)F)N2N=C1C(=O)N(C)CC=1C(C)=NN(C)C=1C IZYULJPASQYGFY-UHFFFAOYSA-N 0.000 claims 1
• GMCRTOFQUQRORH-UHFFFAOYSA-N 5-[4-ethyl-5-[(2-nitrophenyl)methylsulfanyl]-1,2,4-triazol-3-yl]-4-phenylthiadiazole Chemical compound N=1N=C(C2=C(N=NS2)C=2C=CC=CC=2)N(CC)C=1SCC1=CC=CC=C1[N+]([O-])=O GMCRTOFQUQRORH-UHFFFAOYSA-N 0.000 claims 1
• WIYDGCODYJENAJ-UHFFFAOYSA-N 5-[4-ethyl-5-[(3-nitrophenyl)methylsulfanyl]-1,2,4-triazol-3-yl]-4-methylthiadiazole Chemical compound N=1N=C(C2=C(N=NS2)C)N(CC)C=1SCC1=CC=CC([N+]([O-])=O)=C1 WIYDGCODYJENAJ-UHFFFAOYSA-N 0.000 claims 1
• YBSJPOOWFXUMQU-UHFFFAOYSA-N 5-[4-ethyl-5-[(4-methoxyphenyl)methylsulfanyl]-1,2,4-triazol-3-yl]-4-phenylthiadiazole Chemical compound N=1N=C(C2=C(N=NS2)C=2C=CC=CC=2)N(CC)C=1SCC1=CC=C(OC)C=C1 YBSJPOOWFXUMQU-UHFFFAOYSA-N 0.000 claims 1
• PIYLRUHJJOWQJZ-UHFFFAOYSA-N 5-[4-ethyl-5-[(4-methylphenyl)methylsulfanyl]-1,2,4-triazol-3-yl]-4-methylthiadiazole Chemical compound N=1N=C(C2=C(N=NS2)C)N(CC)C=1SCC1=CC=C(C)C=C1 PIYLRUHJJOWQJZ-UHFFFAOYSA-N 0.000 claims 1
• WIYXDBSTARSLOO-UHFFFAOYSA-N 5-[4-ethyl-5-[(4-methylsulfonylphenyl)methylsulfanyl]-1,2,4-triazol-3-yl]-4-phenylthiadiazole Chemical compound N=1N=C(C2=C(N=NS2)C=2C=CC=CC=2)N(CC)C=1SCC1=CC=C(S(C)(=O)=O)C=C1 WIYXDBSTARSLOO-UHFFFAOYSA-N 0.000 claims 1
• ULGAGQOSUPPNBN-UHFFFAOYSA-N 5-[4-ethyl-5-[(4-nitrophenyl)methylsulfanyl]-1,2,4-triazol-3-yl]-4-methylthiadiazole Chemical compound N=1N=C(C2=C(N=NS2)C)N(CC)C=1SCC1=CC=C([N+]([O-])=O)C=C1 ULGAGQOSUPPNBN-UHFFFAOYSA-N 0.000 claims 1
• PTZFSCPCFICDKE-UHFFFAOYSA-N 5-[4-ethyl-5-[(4-nitrophenyl)methylsulfanyl]-1,2,4-triazol-3-yl]-4-phenylthiadiazole Chemical compound N=1N=C(C2=C(N=NS2)C=2C=CC=CC=2)N(CC)C=1SCC1=CC=C([N+]([O-])=O)C=C1 PTZFSCPCFICDKE-UHFFFAOYSA-N 0.000 claims 1
• KNLYROCUENWUNH-UHFFFAOYSA-N 5-[4-ethyl-5-[(4-phenylmethoxyphenyl)methylsulfanyl]-1,2,4-triazol-3-yl]-4-methylthiadiazole Chemical compound N=1N=C(C2=C(N=NS2)C)N(CC)C=1SCC(C=C1)=CC=C1OCC1=CC=CC=C1 KNLYROCUENWUNH-UHFFFAOYSA-N 0.000 claims 1
• HELOFIMEKFGUFT-UHFFFAOYSA-N 5-[4-ethyl-5-[(5-methyl-2-nitrophenyl)methylsulfanyl]-1,2,4-triazol-3-yl]-4-methylthiadiazole Chemical compound N=1N=C(C2=C(N=NS2)C)N(CC)C=1SCC1=CC(C)=CC=C1[N+]([O-])=O HELOFIMEKFGUFT-UHFFFAOYSA-N 0.000 claims 1
• MPDOWSIGCCTHRK-UHFFFAOYSA-N 5-[4-ethyl-5-[[3-(trifluoromethoxy)phenyl]methylsulfanyl]-1,2,4-triazol-3-yl]-4-methylthiadiazole Chemical compound N=1N=C(C2=C(N=NS2)C)N(CC)C=1SCC1=CC=CC(OC(F)(F)F)=C1 MPDOWSIGCCTHRK-UHFFFAOYSA-N 0.000 claims 1
• WLVFKQMKARUGCQ-UHFFFAOYSA-N 5-[4-ethyl-5-[[3-(trifluoromethoxy)phenyl]methylsulfanyl]-1,2,4-triazol-3-yl]-4-phenylthiadiazole Chemical compound N=1N=C(C2=C(N=NS2)C=2C=CC=CC=2)N(CC)C=1SCC1=CC=CC(OC(F)(F)F)=C1 WLVFKQMKARUGCQ-UHFFFAOYSA-N 0.000 claims 1
• AGRVLUMFTPUVSP-UHFFFAOYSA-N 5-[4-ethyl-5-[[4-(trifluoromethoxy)phenyl]methylsulfanyl]-1,2,4-triazol-3-yl]-4-phenylthiadiazole Chemical compound N=1N=C(C2=C(N=NS2)C=2C=CC=CC=2)N(CC)C=1SCC1=CC=C(OC(F)(F)F)C=C1 AGRVLUMFTPUVSP-UHFFFAOYSA-N 0.000 claims 1
• HCRCOJHFLXMDRU-UHFFFAOYSA-N 5-[4-ethyl-5-[[4-(trifluoromethyl)phenyl]methylsulfanyl]-1,2,4-triazol-3-yl]-4-phenylthiadiazole Chemical compound N=1N=C(C2=C(N=NS2)C=2C=CC=CC=2)N(CC)C=1SCC1=CC=C(C(F)(F)F)C=C1 HCRCOJHFLXMDRU-UHFFFAOYSA-N 0.000 claims 1
• GDHWYPBGPYZSNV-UHFFFAOYSA-N 5-[5-(cyclohexylmethylsulfanyl)-4-ethyl-1,2,4-triazol-3-yl]-4-methylthiadiazole Chemical compound N=1N=C(C2=C(N=NS2)C)N(CC)C=1SCC1CCCCC1 GDHWYPBGPYZSNV-UHFFFAOYSA-N 0.000 claims 1
• PLEFNGIASSCQRD-UHFFFAOYSA-N 5-[5-[(2,4-dichlorophenyl)methylsulfanyl]-4-ethyl-1,2,4-triazol-3-yl]-4-methylthiadiazole Chemical compound N=1N=C(C2=C(N=NS2)C)N(CC)C=1SCC1=CC=C(Cl)C=C1Cl PLEFNGIASSCQRD-UHFFFAOYSA-N 0.000 claims 1
• COTPJWMSWOLYKU-UHFFFAOYSA-N 5-[5-[(2,6-dichlorophenyl)methylsulfanyl]-4-ethyl-1,2,4-triazol-3-yl]-4-phenylthiadiazole Chemical compound N=1N=C(C2=C(N=NS2)C=2C=CC=CC=2)N(CC)C=1SCC1=C(Cl)C=CC=C1Cl COTPJWMSWOLYKU-UHFFFAOYSA-N 0.000 claims 1
• YLCJOOXIGBWUFG-UHFFFAOYSA-N 5-[5-[(2,6-dichlorophenyl)methylsulfanyl]-4-methyl-1,2,4-triazol-3-yl]-2,1,3-benzoxadiazole Chemical compound N=1N=C(C2=CC3=NON=C3C=C2)N(C)C=1SCC1=C(Cl)C=CC=C1Cl YLCJOOXIGBWUFG-UHFFFAOYSA-N 0.000 claims 1
• PDEYVTBPXABOGW-UHFFFAOYSA-N 5-[5-[(3,4-dichlorophenyl)methylsulfanyl]-4-ethyl-1,2,4-triazol-3-yl]-4-methylthiadiazole Chemical compound N=1N=C(C2=C(N=NS2)C)N(CC)C=1SCC1=CC=C(Cl)C(Cl)=C1 PDEYVTBPXABOGW-UHFFFAOYSA-N 0.000 claims 1
• SHOZSGWWWCBHCX-UHFFFAOYSA-N 5-[5-[(3,4-dichlorophenyl)methylsulfanyl]-4-ethyl-1,2,4-triazol-3-yl]-4-phenylthiadiazole Chemical compound N=1N=C(C2=C(N=NS2)C=2C=CC=CC=2)N(CC)C=1SCC1=CC=C(Cl)C(Cl)=C1 SHOZSGWWWCBHCX-UHFFFAOYSA-N 0.000 claims 1
• JBAIXVFOAKAVAX-UHFFFAOYSA-N 5-[5-[(3,5-dimethoxyphenyl)methylsulfanyl]-4-ethyl-1,2,4-triazol-3-yl]-4-methylthiadiazole Chemical compound N=1N=C(C2=C(N=NS2)C)N(CC)C=1SCC1=CC(OC)=CC(OC)=C1 JBAIXVFOAKAVAX-UHFFFAOYSA-N 0.000 claims 1
• NAASMWQSCVYQOD-UHFFFAOYSA-N 5-[5-[(3,5-dimethoxyphenyl)methylsulfanyl]-4-ethyl-1,2,4-triazol-3-yl]-4-phenylthiadiazole Chemical compound N=1N=C(C2=C(N=NS2)C=2C=CC=CC=2)N(CC)C=1SCC1=CC(OC)=CC(OC)=C1 NAASMWQSCVYQOD-UHFFFAOYSA-N 0.000 claims 1
• VGPZUVIKQALJIK-UHFFFAOYSA-N 5-[5-[(4-bromophenyl)methylsulfanyl]-4-ethyl-1,2,4-triazol-3-yl]-4-methylthiadiazole Chemical compound N=1N=C(C2=C(N=NS2)C)N(CC)C=1SCC1=CC=C(Br)C=C1 VGPZUVIKQALJIK-UHFFFAOYSA-N 0.000 claims 1
• GQGUJPJCFRQIMD-UHFFFAOYSA-N 5-amino-N-(2,3-dihydro-1H-inden-2-yl)-N-[(3-hydroxyphenyl)methyl]-2-(propanoylamino)pentanamide Chemical compound C1C2=CC=CC=C2CC1N(C(=O)C(CCCN)NC(=O)CC)CC1=CC=CC(O)=C1 GQGUJPJCFRQIMD-UHFFFAOYSA-N 0.000 claims 1
• IJRFGJFAHIMCIX-UHFFFAOYSA-N 5-methyl-2-[4-(3,3,5-trimethyl-7-azabicyclo[3.2.1]octane-7-carbonyl)phenyl]-4H-pyrazol-3-one Chemical compound O=C1CC(C)=NN1C1=CC=C(C(=O)N2C3CC(CC(C)(C)C3)(C)C2)C=C1 IJRFGJFAHIMCIX-UHFFFAOYSA-N 0.000 claims 1
• BTNJEGWMUWNBFQ-UHFFFAOYSA-N 5-methyl-3-[4-methyl-5-[(4-methylphenyl)methylsulfanyl]-1,2,4-triazol-3-yl]-1,2-oxazole Chemical compound O1C(C)=CC(C=2N(C(SCC=3C=CC(C)=CC=3)=NN=2)C)=N1 BTNJEGWMUWNBFQ-UHFFFAOYSA-N 0.000 claims 1
• IGGCFIIXILTKKF-UHFFFAOYSA-N 6,6-dimethyl-3-(2-nitrophenyl)-5,7-dihydro-1H-[1,2,4]triazolo[4,3-a]pyrimidine Chemical compound N12CC(C)(C)CNC2=NN=C1C1=CC=CC=C1[N+]([O-])=O IGGCFIIXILTKKF-UHFFFAOYSA-N 0.000 claims 1
• DPCREUBFMIHMSO-UHFFFAOYSA-N 6-(3,3,5-trimethyl-7-azabicyclo[3.2.1]octane-7-carbonyl)-1H-indole-3-carbonitrile Chemical compound C1=C2C(C#N)=CNC2=CC(C(=O)N2C3CC(CC(C)(C)C3)(C2)C)=C1 DPCREUBFMIHMSO-UHFFFAOYSA-N 0.000 claims 1
• YEADPLKZJWGUGY-UHFFFAOYSA-N 6-(3,3,5-trimethyl-7-azabicyclo[3.2.1]octane-7-carbonyl)-1H-indole-3-carboxamide Chemical compound C1=C2C(C(N)=O)=CNC2=CC(C(=O)N2C3CC(CC(C)(C)C3)(C2)C)=C1 YEADPLKZJWGUGY-UHFFFAOYSA-N 0.000 claims 1
• AOZLYAFLZFXJGW-UHFFFAOYSA-N 6-(3,3,5-trimethyl-7-azabicyclo[3.2.1]octane-7-carbonyl)-1H-indole-3-carboxylic acid Chemical compound C1=C2C(C(O)=O)=CNC2=CC(C(=O)N2C3CC(CC(C)(C)C3)(C2)C)=C1 AOZLYAFLZFXJGW-UHFFFAOYSA-N 0.000 claims 1
• BEICNKKQKCUVLY-UHFFFAOYSA-N 6-azabicyclo[3.2.1]octan-6-yl(1H-indol-5-yl)methanone Chemical compound C1=C2NC=CC2=CC(C(N2C3CC(CCC3)C2)=O)=C1 BEICNKKQKCUVLY-UHFFFAOYSA-N 0.000 claims 1
• RXTIISNZXPWFRE-UHFFFAOYSA-N 6-azabicyclo[3.2.1]octan-6-yl(1H-indol-6-yl)methanone Chemical compound C1=C2C=CNC2=CC(C(N2C3CC(CCC3)C2)=O)=C1 RXTIISNZXPWFRE-UHFFFAOYSA-N 0.000 claims 1
• AHQPDKZRNZQLSQ-UHFFFAOYSA-N 7,10-dimethoxy-5,5-dimethyl-3-phenyl-6H-[1,2,4]triazolo[3,4-a]isoquinoline Chemical compound N12C(C)(C)CC=3C(OC)=CC=C(OC)C=3C2=NN=C1C1=CC=CC=C1 AHQPDKZRNZQLSQ-UHFFFAOYSA-N 0.000 claims 1
• TZGPPWSIDWDMFA-UHFFFAOYSA-N 7-(1,3-benzodioxol-5-yl)-8-benzyl-8-azabicyclo[3.2.1]octan-4-one Chemical compound O=C1CCC2C(C=3C=C4OCOC4=CC=3)CC1N2CC1=CC=CC=C1 TZGPPWSIDWDMFA-UHFFFAOYSA-N 0.000 claims 1
• FRVNEDJZGFPOOY-UHFFFAOYSA-N 7-(difluoromethyl)-N-[(1-ethyl-3-methylpyrazol-4-yl)methyl]-5-(4-methoxyphenyl)-N-methylpyrazolo[1,5-a]pyrimidine-3-carboxamide Chemical compound CC1=NN(CC)C=C1CN(C)C(=O)C1=C2N=C(C=3C=CC(OC)=CC=3)C=C(C(F)F)N2N=C1 FRVNEDJZGFPOOY-UHFFFAOYSA-N 0.000 claims 1
• RUNBGQGFOAAVCJ-UHFFFAOYSA-N 7-(difluoromethyl)-N-[(1-ethyl-3-methylpyrazol-4-yl)methyl]-N-methyl-5-phenylpyrazolo[1,5-a]pyrimidine-3-carboxamide Chemical compound CC1=NN(CC)C=C1CN(C)C(=O)C1=C2N=C(C=3C=CC=CC=3)C=C(C(F)F)N2N=C1 RUNBGQGFOAAVCJ-UHFFFAOYSA-N 0.000 claims 1
• DFWYLVSJBBCXND-UHFFFAOYSA-N 7-(difluoromethyl)-N-[(1-ethyl-5-methylpyrazol-4-yl)methyl]-N-methyl-5-(4-methylphenyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide Chemical compound CCN1N=CC(CN(C)C(=O)C2=C3N=C(C=C(N3N=C2)C(F)F)C=2C=CC(C)=CC=2)=C1C DFWYLVSJBBCXND-UHFFFAOYSA-N 0.000 claims 1
• HQQYSYGDZZFZDL-UHFFFAOYSA-N 7-(difluoromethyl)-N-methyl-5-(4-methylphenyl)-N-[(1-methylpyrazol-4-yl)methyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide Chemical compound C1=NN2C(C(F)F)=CC(C=3C=CC(C)=CC=3)=NC2=C1C(=O)N(C)CC=1C=NN(C)C=1 HQQYSYGDZZFZDL-UHFFFAOYSA-N 0.000 claims 1
• LMBLGFDIFWDELY-UHFFFAOYSA-N 7-(difluoromethyl)-N-methyl-5-phenyl-N-[(1,3,5-trimethylpyrazol-4-yl)methyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide Chemical compound C1=NN2C(C(F)F)=CC(C=3C=CC=CC=3)=NC2=C1C(=O)N(C)CC=1C(C)=NN(C)C=1C LMBLGFDIFWDELY-UHFFFAOYSA-N 0.000 claims 1
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• DQMTXSQDKOEKNJ-UHFFFAOYSA-N 8-(1H-indole-5-carbonyl)-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one Chemical compound C=1C=C2NC=CC2=CC=1C(=O)N(CC1)CCC1(C(NC1)=O)N1C1=CC=CC=C1 DQMTXSQDKOEKNJ-UHFFFAOYSA-N 0.000 claims 1
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• RWQMIZPNBBYOLE-UHFFFAOYSA-N N-(1-adamantyl)-2-ethoxyacetamide Chemical compound C1C(C2)CC3CC2CC1(NC(=O)COCC)C3 RWQMIZPNBBYOLE-UHFFFAOYSA-N 0.000 claims 1
• DWDQKLYPTWAANY-UHFFFAOYSA-N N-(1-adamantyl)-2-hydroxy-2,2-diphenylacetamide Chemical compound C1C(C2)CC(C3)CC2CC13NC(=O)C(O)(C=1C=CC=CC=1)C1=CC=CC=C1 DWDQKLYPTWAANY-UHFFFAOYSA-N 0.000 claims 1
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• NRTDSWOYZYKYKD-UHFFFAOYSA-N N-(1-adamantyl)-3-(1,3-dioxoisoindol-2-yl)propanamide Chemical compound C1C(C2)CC(C3)CC2CC13NC(=O)CCN1C(=O)C2=CC=CC=C2C1=O NRTDSWOYZYKYKD-UHFFFAOYSA-N 0.000 claims 1
• LUUNFXJXNHGCIA-UHFFFAOYSA-N N-(1-adamantyl)-3-(4-methylphenyl)sulfanylpropanamide Chemical compound C1=CC(C)=CC=C1SCCC(=O)NC1(C2)CC(C3)CC2CC3C1 LUUNFXJXNHGCIA-UHFFFAOYSA-N 0.000 claims 1
• YUNYVNQCZMXLBU-UHFFFAOYSA-N N-(1-adamantyl)-3-morpholin-4-ylpropanamide Chemical compound C1C(C2)CC(C3)CC2CC13NC(=O)CCN1CCOCC1 YUNYVNQCZMXLBU-UHFFFAOYSA-N 0.000 claims 1
• HJAKJMZGMDXFSJ-UHFFFAOYSA-N N-(1-adamantyl)-4-chloro-2-nitrobenzamide Chemical compound [O-][N+](=O)C1=CC(Cl)=CC=C1C(=O)NC1(C2)CC(C3)CC2CC3C1 HJAKJMZGMDXFSJ-UHFFFAOYSA-N 0.000 claims 1
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• WRGIYFUYJJEUKK-UHFFFAOYSA-N N-(1-adamantyl)-N-methylpyridine-4-carboxamide Chemical compound C1C(C2)CC(C3)CC2CC13N(C)C(=O)C1=CC=NC=C1 WRGIYFUYJJEUKK-UHFFFAOYSA-N 0.000 claims 1
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• WXMRRXGEYUXMNT-UHFFFAOYSA-N N-(2,3-dichlorophenyl)-2-[[4-ethyl-5-(2-methoxyphenyl)-1,2,4-triazol-3-yl]sulfanyl]acetamide Chemical compound N=1N=C(C=2C(=CC=CC=2)OC)N(CC)C=1SCC(=O)NC1=CC=CC(Cl)=C1Cl WXMRRXGEYUXMNT-UHFFFAOYSA-N 0.000 claims 1
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• JBIYUSDGIZZPFK-UHFFFAOYSA-N N-(2,3-dimethylphenyl)-4-[methyl-(4-methylphenyl)sulfonylamino]butanamide Chemical compound C=1C=C(C)C=CC=1S(=O)(=O)N(C)CCCC(=O)NC1=CC=CC(C)=C1C JBIYUSDGIZZPFK-UHFFFAOYSA-N 0.000 claims 1
• WTIUYARUCDAMAZ-UHFFFAOYSA-N N-(2,4-difluorophenyl)-3-(4-methylphenyl)adamantane-1-carboxamide Chemical compound C1=CC(C)=CC=C1C1(C2)CC(C3)(C(=O)NC=4C(=CC(F)=CC=4)F)CC2CC3C1 WTIUYARUCDAMAZ-UHFFFAOYSA-N 0.000 claims 1
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• FBDWATZGHYXZFP-UHFFFAOYSA-N N-(2,4-dimethoxyphenyl)-2-[[4-methyl-5-(2-methylphenyl)-1,2,4-triazol-3-yl]sulfanyl]acetamide Chemical compound COC1=CC(OC)=CC=C1NC(=O)CSC(N1C)=NN=C1C1=CC=CC=C1C FBDWATZGHYXZFP-UHFFFAOYSA-N 0.000 claims 1
• KRMOWKXVFDKVGR-UHFFFAOYSA-N N-(2,4-dimethylphenyl)-2-[[4-methyl-5-(2-methylphenyl)-1,2,4-triazol-3-yl]sulfanyl]acetamide Chemical compound CC1=CC(C)=CC=C1NC(=O)CSC(N1C)=NN=C1C1=CC=CC=C1C KRMOWKXVFDKVGR-UHFFFAOYSA-N 0.000 claims 1
• ZOMACASNERZBEN-UHFFFAOYSA-N N-(2,4-dimethylphenyl)-3-(3,3,5-trimethyl-7-azabicyclo[3.2.1]octane-7-carbonyl)benzenesulfonamide Chemical compound CC1=CC(C)=CC=C1NS(=O)(=O)C1=CC=CC(C(=O)N2C3CC(CC(C)(C)C3)(C)C2)=C1 ZOMACASNERZBEN-UHFFFAOYSA-N 0.000 claims 1
• ZMRKCHNOLVTZSZ-UHFFFAOYSA-N N-(2,4-dioxo-1H-pyrimidin-6-yl)adamantane-1-carboxamide Chemical compound C1C(C2)CC(C3)CC2CC13C(=O)NC1=CC(=O)NC(=O)N1 ZMRKCHNOLVTZSZ-UHFFFAOYSA-N 0.000 claims 1
• JGFWCWGZGMGGPZ-UHFFFAOYSA-N N-(2,5-dichlorophenyl)-2-[[4-ethyl-5-(2-methoxyphenyl)-1,2,4-triazol-3-yl]sulfanyl]acetamide Chemical compound N=1N=C(C=2C(=CC=CC=2)OC)N(CC)C=1SCC(=O)NC1=CC(Cl)=CC=C1Cl JGFWCWGZGMGGPZ-UHFFFAOYSA-N 0.000 claims 1
• RKHGNDOZLYTNCV-UHFFFAOYSA-N N-(2,5-dichlorophenyl)-3-(4-methylphenyl)adamantane-1-carboxamide Chemical compound C1=CC(C)=CC=C1C1(C2)CC(C3)(C(=O)NC=4C(=CC=C(Cl)C=4)Cl)CC2CC3C1 RKHGNDOZLYTNCV-UHFFFAOYSA-N 0.000 claims 1
• NNVQBXAWWYCGPB-UHFFFAOYSA-N N-(2,6-dimethoxypyrimidin-4-yl)adamantane-1-carboxamide Chemical compound COC1=NC(OC)=CC(NC(=O)C23CC4CC(CC(C4)C2)C3)=N1 NNVQBXAWWYCGPB-UHFFFAOYSA-N 0.000 claims 1
• SEDGPWXNQMBTGZ-UHFFFAOYSA-N N-(2,6-dimethylpiperidin-1-yl)-1-methylindole-3-carboxamide Chemical compound CC1CCCC(C)N1NC(=O)C1=CN(C)C2=CC=CC=C12 SEDGPWXNQMBTGZ-UHFFFAOYSA-N 0.000 claims 1
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• UYCZMUAUUJYKHR-UHFFFAOYSA-N N-(2-adamantyl)-1H-indole-5-carboxamide Chemical compound C1=C2NC=CC2=CC(C(NC2C3CC4CC(C3)CC2C4)=O)=C1 UYCZMUAUUJYKHR-UHFFFAOYSA-N 0.000 claims 1
• AIPDFMDSZTYMJE-UHFFFAOYSA-N N-(2-adamantyl)-1H-indole-6-carboxamide Chemical compound C1=C2C=CNC2=CC(C(NC2C3CC4CC(C3)CC2C4)=O)=C1 AIPDFMDSZTYMJE-UHFFFAOYSA-N 0.000 claims 1
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• AJUDGEAMZZACBQ-UHFFFAOYSA-N N-(2-benzoyl-4-methylphenyl)-3-phenylprop-2-enamide Chemical compound C=1C=CC=CC=1C(=O)C1=CC(C)=CC=C1NC(=O)C=CC1=CC=CC=C1 AJUDGEAMZZACBQ-UHFFFAOYSA-N 0.000 claims 1
• NLDVEUGIRJVVJG-UHFFFAOYSA-N N-(2-bromo-4-methylphenyl)-2-[(4-ethyl-5-pyridin-4-yl-1,2,4-triazol-3-yl)sulfanyl]acetamide Chemical compound N=1N=C(C=2C=CN=CC=2)N(CC)C=1SCC(=O)NC1=CC=C(C)C=C1Br NLDVEUGIRJVVJG-UHFFFAOYSA-N 0.000 claims 1
• OUZFFRFGAXVTCJ-UHFFFAOYSA-N N-(2-bromo-4-methylphenyl)-2-[(4-methyl-5-phenyl-1,2,4-triazol-3-yl)sulfanyl]acetamide Chemical compound BrC1=CC(C)=CC=C1NC(=O)CSC(N1C)=NN=C1C1=CC=CC=C1 OUZFFRFGAXVTCJ-UHFFFAOYSA-N 0.000 claims 1
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• LQUDRBJASPFYLC-UHFFFAOYSA-N N-(2-bromo-4-methylphenyl)-2-[[5-(3,4-dimethoxyphenyl)-4-methyl-1,2,4-triazol-3-yl]sulfanyl]acetamide Chemical compound C1=C(OC)C(OC)=CC=C1C(N1C)=NN=C1SCC(=O)NC1=CC=C(C)C=C1Br LQUDRBJASPFYLC-UHFFFAOYSA-N 0.000 claims 1
• GMJJBBCOODDOMB-UHFFFAOYSA-N N-(2-bromophenyl)-2-[(4-ethyl-5-phenyl-1,2,4-triazol-3-yl)sulfanyl]acetamide Chemical compound N=1N=C(C=2C=CC=CC=2)N(CC)C=1SCC(=O)NC1=CC=CC=C1Br GMJJBBCOODDOMB-UHFFFAOYSA-N 0.000 claims 1
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• ABJDZBPTRZYDHL-UHFFFAOYSA-N N-(2-chlorophenyl)-2-(1,2,3,4-tetrahydroisoquinolin-1-yl)acetamide Chemical compound ClC1=CC=CC=C1NC(=O)CC1C2=CC=CC=C2CCN1 ABJDZBPTRZYDHL-UHFFFAOYSA-N 0.000 claims 1
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• WXECIJNGIJIJPN-UHFFFAOYSA-N N-(2-chlorophenyl)-2-[[4-methyl-5-(3-methylphenyl)-1,2,4-triazol-3-yl]sulfanyl]acetamide Chemical compound CC1=CC=CC(C=2N(C(SCC(=O)NC=3C(=CC=CC=3)Cl)=NN=2)C)=C1 WXECIJNGIJIJPN-UHFFFAOYSA-N 0.000 claims 1
• CHMRECGWXBZPII-UHFFFAOYSA-N N-(2-chlorophenyl)-2-[[5-(2-methoxyphenyl)-4-methyl-1,2,4-triazol-3-yl]sulfanyl]acetamide Chemical compound COC1=CC=CC=C1C(N1C)=NN=C1SCC(=O)NC1=CC=CC=C1Cl CHMRECGWXBZPII-UHFFFAOYSA-N 0.000 claims 1
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• RPHJYWMIFUXJGX-UHFFFAOYSA-N N-(2-cyanophenyl)-2-[(5-methyl-[1,2,4]triazino[5,6-b]indol-3-yl)sulfanyl]acetamide Chemical compound N1=C2N(C)C3=CC=CC=C3C2=NN=C1SCC(=O)NC1=CC=CC=C1C#N RPHJYWMIFUXJGX-UHFFFAOYSA-N 0.000 claims 1
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• KTELQOCLYHZEMI-UHFFFAOYSA-N N-(2-ethylphenyl)-2-(3-methylpiperidin-1-yl)acetamide Chemical compound CCC1=CC=CC=C1NC(=O)CN1CC(C)CCC1 KTELQOCLYHZEMI-UHFFFAOYSA-N 0.000 claims 1
• MEOUTRNMVUURBE-UHFFFAOYSA-N N-(2-fluorophenyl)adamantane-1-carboxamide Chemical compound FC1=CC=CC=C1NC(=O)C1(C2)CC(C3)CC2CC3C1 MEOUTRNMVUURBE-UHFFFAOYSA-N 0.000 claims 1
• XYALKAYLERMMCO-UHFFFAOYSA-N N-(2-methoxyethyl)-5-(3,3,5-trimethyl-7-azabicyclo[3.2.1]octane-7-carbonyl)-1H-indole-3-carboxamide Chemical compound C1C(CC(C)(C)C2)(C)CC2N1C(=O)C1=CC=C2NC=C(C(=O)NCCOC)C2=C1 XYALKAYLERMMCO-UHFFFAOYSA-N 0.000 claims 1
• WDWQJJNEHFIHOJ-UHFFFAOYSA-N N-(2-methoxyphenyl)-2-[[4-methyl-5-(2-methylphenyl)-1,2,4-triazol-3-yl]sulfanyl]acetamide Chemical compound COC1=CC=CC=C1NC(=O)CSC(N1C)=NN=C1C1=CC=CC=C1C WDWQJJNEHFIHOJ-UHFFFAOYSA-N 0.000 claims 1
• CNZFKMXIRVXMQL-UHFFFAOYSA-N N-(2-methoxyphenyl)-2-[[4-methyl-5-(3-methylphenyl)-1,2,4-triazol-3-yl]sulfanyl]acetamide Chemical compound COC1=CC=CC=C1NC(=O)CSC(N1C)=NN=C1C1=CC=CC(C)=C1 CNZFKMXIRVXMQL-UHFFFAOYSA-N 0.000 claims 1
• HMZMSGWBOREIDD-UHFFFAOYSA-N N-(2-methoxyphenyl)-2-[[5-(2-methoxyphenyl)-4-methyl-1,2,4-triazol-3-yl]sulfanyl]acetamide Chemical compound COC1=CC=CC=C1NC(=O)CSC(N1C)=NN=C1C1=CC=CC=C1OC HMZMSGWBOREIDD-UHFFFAOYSA-N 0.000 claims 1
• ALEBBVNYTHDZDP-UHFFFAOYSA-N N-(2-methyl-4-nitrophenyl)-2-[[4-(2-phenylethyl)-5-pyridin-4-yl-1,2,4-triazol-3-yl]sulfanyl]acetamide Chemical compound CC1=CC([N+]([O-])=O)=CC=C1NC(=O)CSC(N1CCC=2C=CC=CC=2)=NN=C1C1=CC=NC=C1 ALEBBVNYTHDZDP-UHFFFAOYSA-N 0.000 claims 1
• QEYGWGBJCBXJBX-UHFFFAOYSA-N N-(2-methyl-5-nitrophenyl)-2-[[4-(2-phenylethyl)-5-pyridin-4-yl-1,2,4-triazol-3-yl]sulfanyl]acetamide Chemical compound CC1=CC=C([N+]([O-])=O)C=C1NC(=O)CSC(N1CCC=2C=CC=CC=2)=NN=C1C1=CC=NC=C1 QEYGWGBJCBXJBX-UHFFFAOYSA-N 0.000 claims 1
• LMBDTMZUNIJZDS-UHFFFAOYSA-N N-(2-methylheptan-2-yl)-2-morpholin-4-ylacetamide Chemical compound CCCCCC(C)(C)NC(=O)CN1CCOCC1 LMBDTMZUNIJZDS-UHFFFAOYSA-N 0.000 claims 1
• XJLUUVMDZAFFCS-UHFFFAOYSA-N N-(2-nitrophenyl)-2-[[4-(2-phenylethyl)-5-pyridin-3-yl-1,2,4-triazol-3-yl]sulfanyl]acetamide Chemical compound [O-][N+](=O)C1=CC=CC=C1NC(=O)CSC(N1CCC=2C=CC=CC=2)=NN=C1C1=CC=CN=C1 XJLUUVMDZAFFCS-UHFFFAOYSA-N 0.000 claims 1
• ARXJQUSLZXIZEK-UHFFFAOYSA-N N-(2-oxoazepan-3-yl)-N-(thiophen-3-ylmethyl)naphthalene-2-carboxamide Chemical compound C=1C=C2C=CC=CC2=CC=1C(=O)N(C1C(NCCCC1)=O)CC=1C=CSC=1 ARXJQUSLZXIZEK-UHFFFAOYSA-N 0.000 claims 1
• ADWRGXCJYSOLDN-UHFFFAOYSA-N N-(2-phenylphenyl)-2-pyridin-2-ylsulfanylacetamide Chemical compound C=1C=CC=C(C=2C=CC=CC=2)C=1NC(=O)CSC1=CC=CC=N1 ADWRGXCJYSOLDN-UHFFFAOYSA-N 0.000 claims 1
• RBWBVWSBZRZYFT-UHFFFAOYSA-N N-(2-phenylsulfanylphenyl)cyclohexanecarboxamide Chemical compound C1CCCCC1C(=O)NC1=CC=CC=C1SC1=CC=CC=C1 RBWBVWSBZRZYFT-UHFFFAOYSA-N 0.000 claims 1
• OIBSQOUOPXHPIM-UHFFFAOYSA-N N-(2-propoxyphenyl)cyclohexanecarboxamide Chemical compound CCCOC1=CC=CC=C1NC(=O)C1CCCCC1 OIBSQOUOPXHPIM-UHFFFAOYSA-N 0.000 claims 1
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• PHIREEBXEVROBM-UHFFFAOYSA-N N-(3-chloro-2-methylphenyl)-2-[[4-ethyl-5-(2-methoxyphenyl)-1,2,4-triazol-3-yl]sulfanyl]acetamide Chemical compound N=1N=C(C=2C(=CC=CC=2)OC)N(CC)C=1SCC(=O)NC1=CC=CC(Cl)=C1C PHIREEBXEVROBM-UHFFFAOYSA-N 0.000 claims 1
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• PXEPHSRPBDSLMZ-UHFFFAOYSA-N N-(3-chloro-4-methylphenyl)-2-[[4-ethyl-5-(2-methoxyphenyl)-1,2,4-triazol-3-yl]sulfanyl]acetamide Chemical compound N=1N=C(C=2C(=CC=CC=2)OC)N(CC)C=1SCC(=O)NC1=CC=C(C)C(Cl)=C1 PXEPHSRPBDSLMZ-UHFFFAOYSA-N 0.000 claims 1
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• SORRCFVXHLUUQO-UHFFFAOYSA-N N-(3-chlorophenyl)-2-[(4-ethyl-5-phenyl-1,2,4-triazol-3-yl)sulfanyl]acetamide Chemical compound N=1N=C(C=2C=CC=CC=2)N(CC)C=1SCC(=O)NC1=CC=CC(Cl)=C1 SORRCFVXHLUUQO-UHFFFAOYSA-N 0.000 claims 1
• DPHUWIVGQOBOAU-UHFFFAOYSA-N N-(3-chlorophenyl)-2-[(5-cyclohexyl-4-ethyl-1,2,4-triazol-3-yl)sulfanyl]acetamide Chemical compound N=1N=C(C2CCCCC2)N(CC)C=1SCC(=O)NC1=CC=CC(Cl)=C1 DPHUWIVGQOBOAU-UHFFFAOYSA-N 0.000 claims 1
• SATVWVSLXVHJLQ-UHFFFAOYSA-N N-(3-chlorophenyl)-2-[[4-(2-phenylethyl)-5-pyridin-3-yl-1,2,4-triazol-3-yl]sulfanyl]acetamide Chemical compound ClC1=CC=CC(NC(=O)CSC=2N(C(C=3C=NC=CC=3)=NN=2)CCC=2C=CC=CC=2)=C1 SATVWVSLXVHJLQ-UHFFFAOYSA-N 0.000 claims 1
• RQLWAEFOAJVNGC-UHFFFAOYSA-N N-(3-chlorophenyl)-2-[[4-(furan-2-ylmethyl)-5-(2-methoxyphenyl)-1,2,4-triazol-3-yl]sulfanyl]acetamide Chemical compound COC1=CC=CC=C1C(N1CC=2OC=CC=2)=NN=C1SCC(=O)NC1=CC=CC(Cl)=C1 RQLWAEFOAJVNGC-UHFFFAOYSA-N 0.000 claims 1
• PECWRZGEIHIIFN-UHFFFAOYSA-N N-(3-chlorophenyl)-2-[[4-ethyl-5-(2-methoxyphenyl)-1,2,4-triazol-3-yl]sulfanyl]acetamide Chemical compound N=1N=C(C=2C(=CC=CC=2)OC)N(CC)C=1SCC(=O)NC1=CC=CC(Cl)=C1 PECWRZGEIHIIFN-UHFFFAOYSA-N 0.000 claims 1
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• GTIYDDYACYJWJM-UHFFFAOYSA-N N-(3-cyano-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)-1-cyclohexyl-5-oxopyrrolidine-3-carboxamide Chemical compound S1C=2CCCCC=2C(C#N)=C1NC(=O)C(CC1=O)CN1C1CCCCC1 GTIYDDYACYJWJM-UHFFFAOYSA-N 0.000 claims 1
• XXMHHNDEQCVSFJ-UHFFFAOYSA-N N-(3-cyano-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)-2-[(4-ethyl-5-phenyl-1,2,4-triazol-3-yl)sulfanyl]acetamide Chemical compound CCN1C(SCC(=O)NC2=C(C=3CCCCC=3S2)C#N)=NN=C1C1=CC=CC=C1 XXMHHNDEQCVSFJ-UHFFFAOYSA-N 0.000 claims 1
• XPJLFXGMNKRYBV-UHFFFAOYSA-N N-(3-cyano-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)-2-[(5-cyclohexyl-4-methyl-1,2,4-triazol-3-yl)sulfanyl]acetamide Chemical compound CN1C(SCC(=O)NC2=C(C=3CCCCC=3S2)C#N)=NN=C1C1CCCCC1 XPJLFXGMNKRYBV-UHFFFAOYSA-N 0.000 claims 1
• QDSFVYPBWBVQKY-UHFFFAOYSA-N N-(3-cyano-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)-2-[[4-(furan-2-ylmethyl)-5-pyridin-4-yl-1,2,4-triazol-3-yl]sulfanyl]acetamide Chemical compound S1C=2CCCCC=2C(C#N)=C1NC(=O)CSC(N1CC=2OC=CC=2)=NN=C1C1=CC=NC=C1 QDSFVYPBWBVQKY-UHFFFAOYSA-N 0.000 claims 1
• FZLFKEFJWFIKNC-UHFFFAOYSA-N N-(3-cyano-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)-2-[[4-ethyl-5-(2-methoxyphenyl)-1,2,4-triazol-3-yl]sulfanyl]acetamide Chemical compound CCN1C(SCC(=O)NC2=C(C=3CCCCC=3S2)C#N)=NN=C1C1=CC=CC=C1OC FZLFKEFJWFIKNC-UHFFFAOYSA-N 0.000 claims 1
• HTHKTJIANWVHFF-UHFFFAOYSA-N N-(3-cyano-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)-2-[[5-(2-methoxyphenyl)-4-methyl-1,2,4-triazol-3-yl]sulfanyl]acetamide Chemical compound COC1=CC=CC=C1C(N1C)=NN=C1SCC(=O)NC1=C(C#N)C(CCCC2)=C2S1 HTHKTJIANWVHFF-UHFFFAOYSA-N 0.000 claims 1
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• NDBGMPBQTHIHGD-UHFFFAOYSA-N N-(3-hexylsulfanyl-1,2,4-thiadiazol-5-yl)-3-methylbutanamide Chemical compound CCCCCCSC1=NSC(NC(=O)CC(C)C)=N1 NDBGMPBQTHIHGD-UHFFFAOYSA-N 0.000 claims 1
• LAMZCIPJVZGTTN-UHFFFAOYSA-N N-(3-hydroxy-1-adamantyl)-1-methylindole-3-carboxamide Chemical compound C12=CC=CC=C2N(C)C=C1C(=O)NC1(C2)CC(O)(C3)CC2CC3C1 LAMZCIPJVZGTTN-UHFFFAOYSA-N 0.000 claims 1
• RUAIWPYLUWJCAM-UHFFFAOYSA-N N-(3-hydroxy-1-adamantyl)-2,4-dimethyl-1,3-thiazole-5-carboxamide Chemical compound S1C(C)=NC(C)=C1C(=O)NC1(C2)CC(O)(C3)CC2CC3C1 RUAIWPYLUWJCAM-UHFFFAOYSA-N 0.000 claims 1
• CRUANUTZEHQTOZ-UHFFFAOYSA-N N-(3-methylbutyl)-9-oxofluorene-1-carboxamide Chemical compound C12=CC=CC=C2C(=O)C2=C1C=CC=C2C(=O)NCCC(C)C CRUANUTZEHQTOZ-UHFFFAOYSA-N 0.000 claims 1
• PAZNKYMKSRAMHZ-UHFFFAOYSA-N N-(3-nitrophenyl)-2-[[4-(2-phenylethyl)-5-pyridin-3-yl-1,2,4-triazol-3-yl]sulfanyl]acetamide Chemical compound [O-][N+](=O)C1=CC=CC(NC(=O)CSC=2N(C(C=3C=NC=CC=3)=NN=2)CCC=2C=CC=CC=2)=C1 PAZNKYMKSRAMHZ-UHFFFAOYSA-N 0.000 claims 1
• PZXTZHMGBQTRIJ-UHFFFAOYSA-N N-(3-nitrophenyl)-2-[[4-(2-phenylethyl)-5-pyridin-4-yl-1,2,4-triazol-3-yl]sulfanyl]acetamide Chemical compound [O-][N+](=O)C1=CC=CC(NC(=O)CSC=2N(C(C=3C=CN=CC=3)=NN=2)CCC=2C=CC=CC=2)=C1 PZXTZHMGBQTRIJ-UHFFFAOYSA-N 0.000 claims 1
• WEGYSVJPPLMZOS-UHFFFAOYSA-N N-(4,6-dimethyl-5-nitropyridin-3-yl)benzamide Chemical compound CC1=C([N+]([O-])=O)C(C)=NC=C1NC(=O)C1=CC=CC=C1 WEGYSVJPPLMZOS-UHFFFAOYSA-N 0.000 claims 1
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• LYNOIZAAFPMWQT-UHFFFAOYSA-N N-(4-acetylphenyl)-2-[(4-benzyl-5-pyridin-3-yl-1,2,4-triazol-3-yl)sulfanyl]acetamide Chemical compound C1=CC(C(=O)C)=CC=C1NC(=O)CSC(N1CC=2C=CC=CC=2)=NN=C1C1=CC=CN=C1 LYNOIZAAFPMWQT-UHFFFAOYSA-N 0.000 claims 1
• DCYRIDDVROEAFQ-UHFFFAOYSA-N N-(4-acetylphenyl)-2-[(5-benzyl-4-ethyl-1,2,4-triazol-3-yl)sulfanyl]acetamide Chemical compound N=1N=C(SCC(=O)NC=2C=CC(=CC=2)C(C)=O)N(CC)C=1CC1=CC=CC=C1 DCYRIDDVROEAFQ-UHFFFAOYSA-N 0.000 claims 1
• VSSIQNUQUMVFGU-UHFFFAOYSA-N N-(4-acetylphenyl)-2-[(5-cyclohexyl-4-ethyl-1,2,4-triazol-3-yl)sulfanyl]acetamide Chemical compound N=1N=C(C2CCCCC2)N(CC)C=1SCC(=O)NC1=CC=C(C(C)=O)C=C1 VSSIQNUQUMVFGU-UHFFFAOYSA-N 0.000 claims 1
• HKKCWUXFWKMTON-UHFFFAOYSA-N N-(4-acetylphenyl)-2-[(5-cyclohexyl-4-methyl-1,2,4-triazol-3-yl)sulfanyl]acetamide Chemical compound C1=CC(C(=O)C)=CC=C1NC(=O)CSC(N1C)=NN=C1C1CCCCC1 HKKCWUXFWKMTON-UHFFFAOYSA-N 0.000 claims 1
• BDGPKIHJGCXARV-UHFFFAOYSA-N N-(4-acetylphenyl)-2-[[4-ethyl-5-(2-methoxyphenyl)-1,2,4-triazol-3-yl]sulfanyl]acetamide Chemical compound N=1N=C(C=2C(=CC=CC=2)OC)N(CC)C=1SCC(=O)NC1=CC=C(C(C)=O)C=C1 BDGPKIHJGCXARV-UHFFFAOYSA-N 0.000 claims 1
• OSQJVDBWQTYHMW-UHFFFAOYSA-N N-(4-acetylphenyl)-2-[[4-ethyl-5-(3-methylphenyl)-1,2,4-triazol-3-yl]sulfanyl]acetamide Chemical compound N=1N=C(C=2C=C(C)C=CC=2)N(CC)C=1SCC(=O)NC1=CC=C(C(C)=O)C=C1 OSQJVDBWQTYHMW-UHFFFAOYSA-N 0.000 claims 1
• JENNAGWUQURNEC-UHFFFAOYSA-N N-(4-benzoyl-1,2,5-oxadiazol-3-yl)-2-fluorobenzamide Chemical compound FC1=CC=CC=C1C(=O)NC1=NON=C1C(=O)C1=CC=CC=C1 JENNAGWUQURNEC-UHFFFAOYSA-N 0.000 claims 1
• PXCUXXQQXFOWJK-UHFFFAOYSA-N N-(4-bromophenyl)-2-[(5-cyclohexyl-4-ethyl-1,2,4-triazol-3-yl)sulfanyl]acetamide Chemical compound N=1N=C(C2CCCCC2)N(CC)C=1SCC(=O)NC1=CC=C(Br)C=C1 PXCUXXQQXFOWJK-UHFFFAOYSA-N 0.000 claims 1
• MEPTZZXYZUSXJQ-UHFFFAOYSA-N N-(4-bromophenyl)-2-[[4-(2-phenylethyl)-5-pyridin-4-yl-1,2,4-triazol-3-yl]sulfanyl]acetamide Chemical compound C1=CC(Br)=CC=C1NC(=O)CSC(N1CCC=2C=CC=CC=2)=NN=C1C1=CC=NC=C1 MEPTZZXYZUSXJQ-UHFFFAOYSA-N 0.000 claims 1
• XCPOOVVFDXQBBU-UHFFFAOYSA-N N-(4-bromophenyl)-2-[[4-ethyl-5-[(4-fluoroanilino)methyl]-1,2,4-triazol-3-yl]sulfanyl]acetamide Chemical compound N=1N=C(SCC(=O)NC=2C=CC(Br)=CC=2)N(CC)C=1CNC1=CC=C(F)C=C1 XCPOOVVFDXQBBU-UHFFFAOYSA-N 0.000 claims 1
• ZZAORWKXJHJAPB-UHFFFAOYSA-N N-(4-bromophenyl)-2-[[5-(2-bromophenyl)-4-ethyl-1,2,4-triazol-3-yl]sulfanyl]acetamide Chemical compound N=1N=C(C=2C(=CC=CC=2)Br)N(CC)C=1SCC(=O)NC1=CC=C(Br)C=C1 ZZAORWKXJHJAPB-UHFFFAOYSA-N 0.000 claims 1
• VJEFEBDPMPLANV-UHFFFAOYSA-N N-(4-chloro-3-nitrophenyl)-1-cyclohexyl-5-oxopyrrolidine-3-carboxamide Chemical compound C1=C(Cl)C([N+](=O)[O-])=CC(NC(=O)C2CC(=O)N(C3CCCCC3)C2)=C1 VJEFEBDPMPLANV-UHFFFAOYSA-N 0.000 claims 1
• HZFLRKOGPXAOAM-UHFFFAOYSA-N N-(4-chloro-3-nitrophenyl)-2-[[4-methyl-5-(2-methylphenyl)-1,2,4-triazol-3-yl]sulfanyl]acetamide Chemical compound CC1=CC=CC=C1C(N1C)=NN=C1SCC(=O)NC1=CC=C(Cl)C([N+]([O-])=O)=C1 HZFLRKOGPXAOAM-UHFFFAOYSA-N 0.000 claims 1
• VMXWMXDCWYRQKH-UHFFFAOYSA-N N-(4-chloro-3-nitrophenyl)-2-[[5-(4-chlorophenyl)-4-ethyl-1,2,4-triazol-3-yl]sulfanyl]acetamide Chemical compound N=1N=C(C=2C=CC(Cl)=CC=2)N(CC)C=1SCC(=O)NC1=CC=C(Cl)C([N+]([O-])=O)=C1 VMXWMXDCWYRQKH-UHFFFAOYSA-N 0.000 claims 1
• HIZNSNLNSQUJCR-UHFFFAOYSA-N N-(4-chlorophenyl)-2-[(5-cyclohexyl-4-methyl-1,2,4-triazol-3-yl)sulfanyl]acetamide Chemical compound N=1N=C(C2CCCCC2)N(C)C=1SCC(=O)NC1=CC=C(Cl)C=C1 HIZNSNLNSQUJCR-UHFFFAOYSA-N 0.000 claims 1
• NAODVMALTYMQBY-UHFFFAOYSA-N N-(4-chlorophenyl)-2-[(5-phenyl-4-prop-2-enyl-1,2,4-triazol-3-yl)sulfanyl]acetamide Chemical compound C1=CC(Cl)=CC=C1NC(=O)CSC(N1CC=C)=NN=C1C1=CC=CC=C1 NAODVMALTYMQBY-UHFFFAOYSA-N 0.000 claims 1
• CQMRXNULWZNTSJ-UHFFFAOYSA-N N-(4-chlorophenyl)-2-[[4-(2-phenylethyl)-5-pyridin-4-yl-1,2,4-triazol-3-yl]sulfanyl]acetamide Chemical compound C1=CC(Cl)=CC=C1NC(=O)CSC(N1CCC=2C=CC=CC=2)=NN=C1C1=CC=NC=C1 CQMRXNULWZNTSJ-UHFFFAOYSA-N 0.000 claims 1
• KBVPNDGMVIVBMJ-UHFFFAOYSA-N N-(4-chlorophenyl)-2-[[4-(furan-2-ylmethyl)-5-(2-methoxyphenyl)-1,2,4-triazol-3-yl]sulfanyl]acetamide Chemical compound COC1=CC=CC=C1C(N1CC=2OC=CC=2)=NN=C1SCC(=O)NC1=CC=C(Cl)C=C1 KBVPNDGMVIVBMJ-UHFFFAOYSA-N 0.000 claims 1
• JTFYOTIJUOSHHF-UHFFFAOYSA-N N-(4-chlorophenyl)-2-[[4-ethyl-5-(2-methoxyphenyl)-1,2,4-triazol-3-yl]sulfanyl]acetamide Chemical compound N=1N=C(C=2C(=CC=CC=2)OC)N(CC)C=1SCC(=O)NC1=CC=C(Cl)C=C1 JTFYOTIJUOSHHF-UHFFFAOYSA-N 0.000 claims 1
• GKZIXEPSOLBANQ-UHFFFAOYSA-N N-(4-chlorophenyl)-2-[[4-ethyl-5-(3-methylphenyl)-1,2,4-triazol-3-yl]sulfanyl]acetamide Chemical compound N=1N=C(C=2C=C(C)C=CC=2)N(CC)C=1SCC(=O)NC1=CC=C(Cl)C=C1 GKZIXEPSOLBANQ-UHFFFAOYSA-N 0.000 claims 1
• CNWFTMQJSZUWMR-UHFFFAOYSA-N N-(4-chlorophenyl)-2-[[4-ethyl-5-[(4-fluoroanilino)methyl]-1,2,4-triazol-3-yl]sulfanyl]acetamide Chemical compound N=1N=C(SCC(=O)NC=2C=CC(Cl)=CC=2)N(CC)C=1CNC1=CC=C(F)C=C1 CNWFTMQJSZUWMR-UHFFFAOYSA-N 0.000 claims 1
• XFOZBELQKKGBIE-UHFFFAOYSA-N N-(4-chlorophenyl)-2-[[4-methyl-5-(2-methylphenyl)-1,2,4-triazol-3-yl]sulfanyl]acetamide Chemical compound CC1=CC=CC=C1C(N1C)=NN=C1SCC(=O)NC1=CC=C(Cl)C=C1 XFOZBELQKKGBIE-UHFFFAOYSA-N 0.000 claims 1
• IRBCFSKQKDNGNZ-UHFFFAOYSA-N N-(4-chlorophenyl)-2-[[4-methyl-5-(thiophen-3-ylmethyl)-1,2,4-triazol-3-yl]sulfanyl]acetamide Chemical compound N=1N=C(SCC(=O)NC=2C=CC(Cl)=CC=2)N(C)C=1CC=1C=CSC=1 IRBCFSKQKDNGNZ-UHFFFAOYSA-N 0.000 claims 1
• WCOODDVFMLCDJL-UHFFFAOYSA-N N-(4-chlorophenyl)-2-[[5-methyl-4-(2-phenylethyl)-1,2,4-triazol-3-yl]sulfanyl]acetamide Chemical compound C=1C=CC=CC=1CCN1C(C)=NN=C1SCC(=O)NC1=CC=C(Cl)C=C1 WCOODDVFMLCDJL-UHFFFAOYSA-N 0.000 claims 1
• OROXEFABSSXTTR-UHFFFAOYSA-N N-(4-ethoxyphenyl)-2-[(4-ethyl-5-phenyl-1,2,4-triazol-3-yl)sulfanyl]acetamide Chemical compound C1=CC(OCC)=CC=C1NC(=O)CSC(N1CC)=NN=C1C1=CC=CC=C1 OROXEFABSSXTTR-UHFFFAOYSA-N 0.000 claims 1
• KBWVLZPAEJCZTE-UHFFFAOYSA-N N-(4-ethoxyphenyl)-2-[[4-ethyl-5-(3-methylphenyl)-1,2,4-triazol-3-yl]sulfanyl]acetamide Chemical compound C1=CC(OCC)=CC=C1NC(=O)CSC(N1CC)=NN=C1C1=CC=CC(C)=C1 KBWVLZPAEJCZTE-UHFFFAOYSA-N 0.000 claims 1
• DFPZIJGUASCDIN-UHFFFAOYSA-N N-(4-ethoxyphenyl)-2-[[4-methyl-5-(2-methylphenyl)-1,2,4-triazol-3-yl]sulfanyl]acetamide Chemical compound C1=CC(OCC)=CC=C1NC(=O)CSC(N1C)=NN=C1C1=CC=CC=C1C DFPZIJGUASCDIN-UHFFFAOYSA-N 0.000 claims 1
• YKECOWKKDWZLET-UHFFFAOYSA-N N-(4-ethylphenyl)-2-[(4-ethyl-5-phenyl-1,2,4-triazol-3-yl)sulfanyl]acetamide Chemical compound C1=CC(CC)=CC=C1NC(=O)CSC(N1CC)=NN=C1C1=CC=CC=C1 YKECOWKKDWZLET-UHFFFAOYSA-N 0.000 claims 1
• WKFJHVXKDNLNMD-UHFFFAOYSA-N N-(4-fluorophenyl)-2-[[4-(2-phenylethyl)-5-pyridin-4-yl-1,2,4-triazol-3-yl]sulfanyl]acetamide Chemical compound C1=CC(F)=CC=C1NC(=O)CSC(N1CCC=2C=CC=CC=2)=NN=C1C1=CC=NC=C1 WKFJHVXKDNLNMD-UHFFFAOYSA-N 0.000 claims 1
• IUGBDURTRTVELS-UHFFFAOYSA-N N-(4-iodo-2-methylphenyl)-2-[[5-(2-methoxyphenyl)-4-methyl-1,2,4-triazol-3-yl]sulfanyl]acetamide Chemical compound COC1=CC=CC=C1C(N1C)=NN=C1SCC(=O)NC1=CC=C(I)C=C1C IUGBDURTRTVELS-UHFFFAOYSA-N 0.000 claims 1
• QMCUEPKMXSQOAE-UHFFFAOYSA-N N-(4-methoxyphenyl)-2-[[4-methyl-5-(2-methylphenyl)-1,2,4-triazol-3-yl]sulfanyl]acetamide Chemical compound C1=CC(OC)=CC=C1NC(=O)CSC(N1C)=NN=C1C1=CC=CC=C1C QMCUEPKMXSQOAE-UHFFFAOYSA-N 0.000 claims 1
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• XUAGYIYYHZBRTG-UHFFFAOYSA-N N-(4-nitrophenyl)-2-[[4-(2-phenylethyl)-5-pyridin-3-yl-1,2,4-triazol-3-yl]sulfanyl]propanamide Chemical compound C=1C=C([N+]([O-])=O)C=CC=1NC(=O)C(C)SC(N1CCC=2C=CC=CC=2)=NN=C1C1=CC=CN=C1 XUAGYIYYHZBRTG-UHFFFAOYSA-N 0.000 claims 1
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• VBBLFLXIEQHQRF-UHFFFAOYSA-N N-(5-chloro-2-methylphenyl)-2-[[4-methyl-5-(2-methylphenyl)-1,2,4-triazol-3-yl]sulfanyl]acetamide Chemical compound CC1=CC=C(Cl)C=C1NC(=O)CSC(N1C)=NN=C1C1=CC=CC=C1C VBBLFLXIEQHQRF-UHFFFAOYSA-N 0.000 claims 1
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• DLGNYUUYPGAJCI-UHFFFAOYSA-N N-(5-hexyl-1,3,4-thiadiazol-2-yl)-2-methylpropanamide Chemical compound CCCCCCC1=NN=C(NC(=O)C(C)C)S1 DLGNYUUYPGAJCI-UHFFFAOYSA-N 0.000 claims 1
• QBWPAMLNPUEMQM-UHFFFAOYSA-N N-(5-methylpyridin-2-yl)adamantane-1-carboxamide Chemical compound N1=CC(C)=CC=C1NC(=O)C1(C2)CC(C3)CC2CC3C1 QBWPAMLNPUEMQM-UHFFFAOYSA-N 0.000 claims 1
• DSLCCYVKHAKUCM-UHFFFAOYSA-N N-(6-hydroxyhexyl)-N-[(4-hydroxyphenyl)methyl]-4-propylbenzamide Chemical compound C1=CC(CCC)=CC=C1C(=O)N(CCCCCCO)CC1=CC=C(O)C=C1 DSLCCYVKHAKUCM-UHFFFAOYSA-N 0.000 claims 1
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• IVJKQKQWJVEAPX-UHFFFAOYSA-N N-(8-methyl-8-azabicyclo[3.2.1]octan-3-yl)-1H-indole-6-carboxamide Chemical compound C1=C2C=CNC2=CC(C(=O)NC2CC3CCC(C2)N3C)=C1 IVJKQKQWJVEAPX-UHFFFAOYSA-N 0.000 claims 1
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• ZTOMRIQLVTWRLT-UHFFFAOYSA-N N-(cyanomethyl)-5-(3,3,5-trimethyl-7-azabicyclo[3.2.1]octane-7-carbonyl)-1H-indole-3-carboxamide Chemical compound C1=C2NC=C(C(=O)NCC#N)C2=CC(C(=O)N2C3CC(CC(C)(C)C3)(C2)C)=C1 ZTOMRIQLVTWRLT-UHFFFAOYSA-N 0.000 claims 1
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• HFPHUGPYWNUHRW-UHFFFAOYSA-N N-(furan-2-ylmethyl)-5-(3,3,5-trimethyl-7-azabicyclo[3.2.1]octane-7-carbonyl)-1H-indole-3-carboxamide Chemical compound C1C(C)(C)CC(C)(C2)CC1N2C(=O)C(C=C12)=CC=C1NC=C2C(=O)NCC1=CC=CO1 HFPHUGPYWNUHRW-UHFFFAOYSA-N 0.000 claims 1
• NHRXPFXVQMNCOV-UHFFFAOYSA-N N-(furan-2-ylmethyl)-N-(4-methylphenyl)adamantane-1-carboxamide Chemical compound C1=CC(C)=CC=C1N(C(=O)C12CC3CC(CC(C3)C1)C2)CC1=CC=CO1 NHRXPFXVQMNCOV-UHFFFAOYSA-N 0.000 claims 1
• WURJNPARHWUNFY-UHFFFAOYSA-N N-(naphthalen-1-ylmethyl)adamantane-1-carboxamide Chemical compound C1C(C2)CC(C3)CC2CC13C(=O)NCC1=CC=CC2=CC=CC=C12 WURJNPARHWUNFY-UHFFFAOYSA-N 0.000 claims 1
• DTMIDUIIAAJUOO-UHFFFAOYSA-N N-(oxolan-2-ylmethyl)-2-(2-phenylethyl)benzamide Chemical compound C=1C=CC=C(CCC=2C=CC=CC=2)C=1C(=O)NCC1CCCO1 DTMIDUIIAAJUOO-UHFFFAOYSA-N 0.000 claims 1
• RNBFYMRWWRWKHZ-UHFFFAOYSA-N N-(oxolan-2-ylmethyl)-5-(3,3,5-trimethyl-7-azabicyclo[3.2.1]octane-7-carbonyl)-1H-indole-3-carboxamide Chemical compound C1C(C)(C)CC(C)(C2)CC1N2C(=O)C(C=C12)=CC=C1NC=C2C(=O)NCC1CCCO1 RNBFYMRWWRWKHZ-UHFFFAOYSA-N 0.000 claims 1
• ZTLHMUKWSKSSEP-UHFFFAOYSA-N N-(oxolan-2-ylmethyl)adamantane-1-carboxamide Chemical compound C1C(C2)CC(C3)CC2CC13C(=O)NCC1CCCO1 ZTLHMUKWSKSSEP-UHFFFAOYSA-N 0.000 claims 1
• NLFJLMOIXJFXNH-UHFFFAOYSA-N N-[(1,3-dimethylpyrazol-4-yl)methyl]-N-methyl-5-phenyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide Chemical compound C1=C2N=C(C=3C=CC=CC=3)C=C(C(F)(F)F)N2N=C1C(=O)N(C)CC1=CN(C)N=C1C NLFJLMOIXJFXNH-UHFFFAOYSA-N 0.000 claims 1
• OPQKNGDNBBMEDA-UHFFFAOYSA-N N-[(1,3-dioxoisoindol-2-yl)methyl]-N-(4-fluorophenyl)benzamide Chemical compound C1=CC(F)=CC=C1N(C(=O)C=1C=CC=CC=1)CN1C(=O)C2=CC=CC=C2C1=O OPQKNGDNBBMEDA-UHFFFAOYSA-N 0.000 claims 1
• VXSKXUTVJQJQAQ-UHFFFAOYSA-N N-[(1,3-dioxoisoindol-2-yl)methyl]-N-(4-hydroxyphenyl)benzamide Chemical compound C1=CC(O)=CC=C1N(C(=O)C=1C=CC=CC=1)CN1C(=O)C2=CC=CC=C2C1=O VXSKXUTVJQJQAQ-UHFFFAOYSA-N 0.000 claims 1
• PJWUAFNNTFUQEE-UHFFFAOYSA-N N-[(1,5-dimethylpyrazol-4-yl)methyl]-N-methyl-5-thiophen-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide Chemical compound C1=C2N=C(C=3SC=CC=3)C=C(C(F)(F)F)N2N=C1C(=O)N(C)CC=1C=NN(C)C=1C PJWUAFNNTFUQEE-UHFFFAOYSA-N 0.000 claims 1
• GINFDOGZDWKVLS-UHFFFAOYSA-N N-[(1-methyl-2,3-dihydroindol-5-yl)methyl]-N-(oxolan-2-ylmethyl)benzamide Chemical compound C=1C=C2N(C)CCC2=CC=1CN(C(=O)C=1C=CC=CC=1)CC1CCCO1 GINFDOGZDWKVLS-UHFFFAOYSA-N 0.000 claims 1
• GHRBREPMRJCPLY-UHFFFAOYSA-N N-[(1-phenylcyclopentyl)methyl]-2-piperidin-1-ylpropanamide Chemical compound C1CCCC1(C=1C=CC=CC=1)CNC(=O)C(C)N1CCCCC1 GHRBREPMRJCPLY-UHFFFAOYSA-N 0.000 claims 1
• VAVLKSDOICPCHK-UHFFFAOYSA-N N-[(2-chlorophenyl)methyl]-N-[(4-hydroxyphenyl)methyl]-2-thiophen-2-ylacetamide Chemical compound C1=CC(O)=CC=C1CN(C(=O)CC=1SC=CC=1)CC1=CC=CC=C1Cl VAVLKSDOICPCHK-UHFFFAOYSA-N 0.000 claims 1
• FNGVCJCDXMEMAT-UHFFFAOYSA-N N-[(2-hydroxyphenyl)methyl]-3-thiophen-3-yl-N-(2-thiophen-2-ylethyl)prop-2-enamide Chemical compound OC1=CC=CC=C1CN(C(=O)C=CC1=CSC=C1)CCC1=CC=CS1 FNGVCJCDXMEMAT-UHFFFAOYSA-N 0.000 claims 1
• GSLNTOBTTFVTSR-UHFFFAOYSA-N N-[(2-hydroxyphenyl)methyl]-N-(2-methylpropyl)benzamide Chemical compound C=1C=CC=CC=1C(=O)N(CC(C)C)CC1=CC=CC=C1O GSLNTOBTTFVTSR-UHFFFAOYSA-N 0.000 claims 1
• JJRQDQPXYISFOI-UHFFFAOYSA-N N-[(2-hydroxyphenyl)methyl]-N-(3-methylbutyl)-4-propylbenzamide Chemical compound C1=CC(CCC)=CC=C1C(=O)N(CCC(C)C)CC1=CC=CC=C1O JJRQDQPXYISFOI-UHFFFAOYSA-N 0.000 claims 1
• TWJPLAKRSAQWDW-UHFFFAOYSA-N N-[(2-hydroxyphenyl)methyl]-N-(3-methylbutyl)benzamide Chemical compound C=1C=CC=CC=1C(=O)N(CCC(C)C)CC1=CC=CC=C1O TWJPLAKRSAQWDW-UHFFFAOYSA-N 0.000 claims 1
• QEXGSNIMFAVYDW-UHFFFAOYSA-N N-[(2-methoxyphenyl)methyl]-3-phenyl-[1,2,4]triazolo[4,3-b]pyridazin-6-amine Chemical compound COC1=CC=CC=C1CNC1=NN2C(C=3C=CC=CC=3)=NN=C2C=C1 QEXGSNIMFAVYDW-UHFFFAOYSA-N 0.000 claims 1
• USSKZFGBHIMMME-UHFFFAOYSA-N N-[(3,4-dimethoxyphenyl)methyl]-3-methoxy-N-[6-(pyridin-2-ylamino)hexyl]benzamide Chemical compound COC1=CC=CC(C(=O)N(CCCCCCNC=2N=CC=CC=2)CC=2C=C(OC)C(OC)=CC=2)=C1 USSKZFGBHIMMME-UHFFFAOYSA-N 0.000 claims 1
• QXZFEPADMBZLFG-UHFFFAOYSA-N N-[(3-hydroxyphenyl)methyl]-2-methyl-3-nitro-N-[(4-sulfamoylphenyl)methyl]benzamide Chemical compound C1=CC=C([N+]([O-])=O)C(C)=C1C(=O)N(CC=1C=C(O)C=CC=1)CC1=CC=C(S(N)(=O)=O)C=C1 QXZFEPADMBZLFG-UHFFFAOYSA-N 0.000 claims 1
• RRTTTYAOACTRLH-UHFFFAOYSA-N N-[(3-hydroxyphenyl)methyl]-N-(3-propan-2-yloxypropyl)benzamide Chemical compound C=1C=CC=CC=1C(=O)N(CCCOC(C)C)CC1=CC=CC(O)=C1 RRTTTYAOACTRLH-UHFFFAOYSA-N 0.000 claims 1
• ZEYNZPOUBJJRNL-UHFFFAOYSA-N N-[(3-hydroxyphenyl)methyl]-N-(4-methylpentyl)benzamide Chemical compound C=1C=CC=CC=1C(=O)N(CCCC(C)C)CC1=CC=CC(O)=C1 ZEYNZPOUBJJRNL-UHFFFAOYSA-N 0.000 claims 1
• NRPVGZUSINBTMC-UHFFFAOYSA-N N-[(3-hydroxyphenyl)methyl]-N-[(4-propan-2-ylphenyl)methyl]heptanamide Chemical compound C=1C=CC(O)=CC=1CN(C(=O)CCCCCC)CC1=CC=C(C(C)C)C=C1 NRPVGZUSINBTMC-UHFFFAOYSA-N 0.000 claims 1
• YSZOMHNVGDQPMU-UHFFFAOYSA-N N-[(3-hydroxyphenyl)methyl]-N-[2-(2-methoxyphenyl)ethyl]-2-methylpent-4-enamide Chemical compound COC1=CC=CC=C1CCN(C(=O)C(C)CC=C)CC1=CC=CC(O)=C1 YSZOMHNVGDQPMU-UHFFFAOYSA-N 0.000 claims 1
• XMRWHMWLDJUBBZ-UHFFFAOYSA-N N-[(4-bromophenyl)methyl]-N-[(4-hydroxyphenyl)methyl]-2-naphthalen-1-ylacetamide Chemical compound C1=CC(O)=CC=C1CN(C(=O)CC=1C2=CC=CC=C2C=CC=1)CC1=CC=C(Br)C=C1 XMRWHMWLDJUBBZ-UHFFFAOYSA-N 0.000 claims 1
• NBENJNKWKCXLAB-UHFFFAOYSA-N N-[(4-fluorophenyl)methyl]-N-[(4-hydroxyphenyl)methyl]-2-thiophen-3-ylacetamide Chemical compound C1=CC(O)=CC=C1CN(C(=O)CC1=CSC=C1)CC1=CC=C(F)C=C1 NBENJNKWKCXLAB-UHFFFAOYSA-N 0.000 claims 1
• VOWHPZYBTLSKGE-UHFFFAOYSA-N N-[(4-fluorophenyl)methyl]-N-[(4-hydroxyphenyl)methyl]-4-methylpentanamide Chemical compound C=1C=C(F)C=CC=1CN(C(=O)CCC(C)C)CC1=CC=C(O)C=C1 VOWHPZYBTLSKGE-UHFFFAOYSA-N 0.000 claims 1
• GFFPUGHJPPMFPR-UHFFFAOYSA-N N-[(4-hydroxyphenyl)methyl]-6-oxo-6-phenyl-N-[[4-(trifluoromethyl)phenyl]methyl]hexanamide Chemical compound C1=CC(O)=CC=C1CN(C(=O)CCCCC(=O)C=1C=CC=CC=1)CC1=CC=C(C(F)(F)F)C=C1 GFFPUGHJPPMFPR-UHFFFAOYSA-N 0.000 claims 1
• CPFNJNJDMSVPFK-UHFFFAOYSA-N N-[(4-hydroxyphenyl)methyl]-N-(2-methylpropyl)benzamide Chemical compound C=1C=CC=CC=1C(=O)N(CC(C)C)CC1=CC=C(O)C=C1 CPFNJNJDMSVPFK-UHFFFAOYSA-N 0.000 claims 1
• VQFVBRBHOPGVJQ-UHFFFAOYSA-N N-[(4-hydroxyphenyl)methyl]-N-(3-methylbutyl)-4-propylbenzamide Chemical compound C1=CC(CCC)=CC=C1C(=O)N(CCC(C)C)CC1=CC=C(O)C=C1 VQFVBRBHOPGVJQ-UHFFFAOYSA-N 0.000 claims 1
• ASANEODLTKPBTJ-UHFFFAOYSA-N N-[(4-hydroxyphenyl)methyl]-N-(3-methylbutyl)benzamide Chemical compound C=1C=CC=CC=1C(=O)N(CCC(C)C)CC1=CC=C(O)C=C1 ASANEODLTKPBTJ-UHFFFAOYSA-N 0.000 claims 1
• ACTJJEUWBVIISW-UHFFFAOYSA-N N-[(4-hydroxyphenyl)methyl]-N-(3-propan-2-yloxypropyl)benzamide Chemical compound C=1C=CC=CC=1C(=O)N(CCCOC(C)C)CC1=CC=C(O)C=C1 ACTJJEUWBVIISW-UHFFFAOYSA-N 0.000 claims 1
• ASBHVXQJQYSXHO-UHFFFAOYSA-N N-[(4-hydroxyphenyl)methyl]-N-[[4-(trifluoromethyl)phenyl]methyl]dec-3-enamide Chemical compound C=1C=C(C(F)(F)F)C=CC=1CN(C(=O)CC=CCCCCCC)CC1=CC=C(O)C=C1 ASBHVXQJQYSXHO-UHFFFAOYSA-N 0.000 claims 1
• OYTJXXFVCAJCET-UHFFFAOYSA-N N-[(4-methoxyphenyl)methyl]-5-(3,3,5-trimethyl-7-azabicyclo[3.2.1]octane-7-carbonyl)-1H-indole-3-carboxamide Chemical compound C1=CC(OC)=CC=C1CNC(=O)C1=CNC2=CC=C(C(=O)N3C4CC(CC(C)(C)C4)(C)C3)C=C12 OYTJXXFVCAJCET-UHFFFAOYSA-N 0.000 claims 1
• HSNPWNNEBQGHIO-UHFFFAOYSA-N N-[(5-benzylsulfanyl-4-ethyl-1,2,4-triazol-3-yl)methyl]-3-(trifluoromethyl)aniline Chemical compound N=1N=C(SCC=2C=CC=CC=2)N(CC)C=1CNC1=CC=CC(C(F)(F)F)=C1 HSNPWNNEBQGHIO-UHFFFAOYSA-N 0.000 claims 1
• HXHMFOCQKVNKSX-UHFFFAOYSA-N N-[(5-benzylsulfanyl-4-ethyl-1,2,4-triazol-3-yl)methyl]-4-chloroaniline Chemical compound N=1N=C(SCC=2C=CC=CC=2)N(CC)C=1CNC1=CC=C(Cl)C=C1 HXHMFOCQKVNKSX-UHFFFAOYSA-N 0.000 claims 1
• MWCLCCDPVFUOHF-UHFFFAOYSA-N N-[(5-benzylsulfanyl-4-ethyl-1,2,4-triazol-3-yl)methyl]-4-fluoroaniline Chemical compound N=1N=C(SCC=2C=CC=CC=2)N(CC)C=1CNC1=CC=C(F)C=C1 MWCLCCDPVFUOHF-UHFFFAOYSA-N 0.000 claims 1
• URGWKIHKPADQEK-UHFFFAOYSA-N N-[(5-hydroxy-1,3,3-trimethylcyclohexyl)methyl]-1H-indole-5-carboxamide Chemical compound C1C(C)(C)CC(O)CC1(C)CNC(=O)C1=CC=C(NC=C2)C2=C1 URGWKIHKPADQEK-UHFFFAOYSA-N 0.000 claims 1
• NTUKVZBNVAGCCU-UHFFFAOYSA-N N-[(6,6-dimethyl-4-bicyclo[3.1.1]heptanyl)methyl]-2-(4-methylphenoxy)acetamide Chemical compound C1=CC(C)=CC=C1OCC(=O)NCC1C(C2(C)C)CC2CC1 NTUKVZBNVAGCCU-UHFFFAOYSA-N 0.000 claims 1
• CDHCEBSOSLZVMO-UHFFFAOYSA-N N-[(6,6-dimethyl-4-bicyclo[3.1.1]heptanyl)methyl]-5-[(3-methylsulfanyl-1,2,4-thiadiazol-5-yl)sulfanyl]pentanamide Chemical compound CSC1=NSC(SCCCCC(=O)NCC2C3CC(C3(C)C)CC2)=N1 CDHCEBSOSLZVMO-UHFFFAOYSA-N 0.000 claims 1
• IBVKTCPCJMRCSA-UHFFFAOYSA-N N-[1-(1-adamantyl)ethyl]-2,3-dihydro-1,4-benzodioxine-6-carboxamide Chemical compound C1C(C2)CC(C3)CC2CC13C(C)NC(=O)C1=CC=C(OCCO2)C2=C1 IBVKTCPCJMRCSA-UHFFFAOYSA-N 0.000 claims 1
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• VRSWNXIEMWQXOU-UHFFFAOYSA-N N-[1-(1-adamantyl)ethyl]-5-methylfuran-2-carboxamide Chemical compound C1C(C2)CC(C3)CC2CC13C(C)NC(=O)C1=CC=C(C)O1 VRSWNXIEMWQXOU-UHFFFAOYSA-N 0.000 claims 1
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• QKZYFEVSPOZFPU-UHFFFAOYSA-N N-[2-(3,4-dimethoxyphenyl)ethyl]adamantane-1-carboxamide Chemical compound C1=C(OC)C(OC)=CC=C1CCNC(=O)C1(C2)CC(C3)CC2CC3C1 QKZYFEVSPOZFPU-UHFFFAOYSA-N 0.000 claims 1
• XAHAAWXDAQHWBU-UHFFFAOYSA-N N-[2-(4-methoxyphenyl)ethyl]adamantane-1-carboxamide Chemical compound C1=CC(OC)=CC=C1CCNC(=O)C1(C2)CC(C3)CC2CC3C1 XAHAAWXDAQHWBU-UHFFFAOYSA-N 0.000 claims 1
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• WRSAPVFSDCSPOJ-UHFFFAOYSA-N N-[2-(azepan-1-yl)-2-oxoethyl]-N-(4-ethoxyphenyl)-4-methylsulfanylbenzenesulfonamide Chemical compound C1=CC(OCC)=CC=C1N(S(=O)(=O)C=1C=CC(SC)=CC=1)CC(=O)N1CCCCCC1 WRSAPVFSDCSPOJ-UHFFFAOYSA-N 0.000 claims 1
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• CLBSULJBGZYOFD-UHFFFAOYSA-N N-[2-(azepan-1-yl)-2-oxoethyl]-N-benzyl-4-bromobenzenesulfonamide Chemical compound C1=CC(Br)=CC=C1S(=O)(=O)N(CC=1C=CC=CC=1)CC(=O)N1CCCCCC1 CLBSULJBGZYOFD-UHFFFAOYSA-N 0.000 claims 1
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• GMNVFEWSZLMHGA-UHFFFAOYSA-N N-[2-(cyclohexen-1-yl)ethyl]-3-methoxybenzamide Chemical compound COC1=CC=CC(C(=O)NCCC=2CCCCC=2)=C1 GMNVFEWSZLMHGA-UHFFFAOYSA-N 0.000 claims 1
• WWZYAMAABWPOGT-UHFFFAOYSA-N N-[2-(cyclohexen-1-yl)ethyl]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide Chemical compound C=1SC=2CCCCC=2C=1C(=O)NCCC1=CCCCC1 WWZYAMAABWPOGT-UHFFFAOYSA-N 0.000 claims 1
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• YNUMZAUJPFCUSI-UHFFFAOYSA-N N-[2-[1-(1,3-benzodioxol-5-yl)-3-(furan-2-yl)-3-oxopropyl]sulfanylphenyl]acetamide Chemical compound CC(=O)NC1=CC=CC=C1SC(C=1C=C2OCOC2=CC=1)CC(=O)C1=CC=CO1 YNUMZAUJPFCUSI-UHFFFAOYSA-N 0.000 claims 1
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• BIEBTXYZDFEXFI-UHFFFAOYSA-N N-[2-[2-[(2-chloro-6-fluorophenyl)methylsulfanyl]ethylamino]-2-oxoethyl]-4-methyl-N-prop-2-ynylcyclohexane-1-carboxamide Chemical compound C1CC(C)CCC1C(=O)N(CC#C)CC(=O)NCCSCC1=C(F)C=CC=C1Cl BIEBTXYZDFEXFI-UHFFFAOYSA-N 0.000 claims 1
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• JOCWJCGOLBOXPJ-UHFFFAOYSA-N N-[3-(3,3,5-trimethyl-7-azabicyclo[3.2.1]octane-7-carbonyl)-1H-indol-7-yl]acetamide Chemical compound C1C(CC(C)(C)C2)(C)CC2N1C(=O)C1=CNC2=C1C=CC=C2NC(=O)C JOCWJCGOLBOXPJ-UHFFFAOYSA-N 0.000 claims 1
• YOYOWAJKBHTARZ-UHFFFAOYSA-N N-[3-(4-methylpiperazin-1-yl)propyl]-5-(3,3,5-trimethyl-7-azabicyclo[3.2.1]octane-7-carbonyl)-1H-indole-3-carboxamide Chemical compound C1CN(C)CCN1CCCNC(=O)C1=CNC2=CC=C(C(=O)N3C4CC(CC(C)(C)C4)(C)C3)C=C12 YOYOWAJKBHTARZ-UHFFFAOYSA-N 0.000 claims 1
• DMSAENNRNBICQZ-UHFFFAOYSA-N N-[3-(azepane-1-carbonyl)phenyl]benzamide Chemical compound C=1C=CC=CC=1C(=O)NC(C=1)=CC=CC=1C(=O)N1CCCCCC1 DMSAENNRNBICQZ-UHFFFAOYSA-N 0.000 claims 1
• FAAOHNFHEPYQPZ-UHFFFAOYSA-N N-[3-methyl-1-oxo-1-(3,3,5-trimethyl-7-azabicyclo[3.2.1]octan-7-yl)pentan-2-yl]cyclohexanecarboxamide Chemical compound C1C(CC(C)(C)C2)(C)CC2N1C(=O)C(C(C)CC)NC(=O)C1CCCCC1 FAAOHNFHEPYQPZ-UHFFFAOYSA-N 0.000 claims 1
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• JCZHIUIBWFMQAP-UHFFFAOYSA-N N-[4-(3,3,5-trimethyl-7-azabicyclo[3.2.1]octane-7-carbonyl)phenyl]acetamide Chemical compound C1=CC(NC(=O)C)=CC=C1C(=O)N1C(CC(C)(C)C2)CC2(C)C1 JCZHIUIBWFMQAP-UHFFFAOYSA-N 0.000 claims 1
• AAYDTRXEZOFOGV-UHFFFAOYSA-N N-[4-(3,3,5-trimethyl-7-azabicyclo[3.2.1]octane-7-carbonyl)phenyl]thiophene-2-sulfonamide Chemical compound C1C(C)(C)CC(C)(C2)CC1N2C(=O)C(C=C1)=CC=C1NS(=O)(=O)C1=CC=CS1 AAYDTRXEZOFOGV-UHFFFAOYSA-N 0.000 claims 1
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• HUTRBWHPRNSUPR-UHFFFAOYSA-N N-[4-[(4-ethyl-5-pyridin-3-yl-1,2,4-triazol-3-yl)sulfanylmethyl]phenyl]acetamide Chemical compound N=1N=C(C=2C=NC=CC=2)N(CC)C=1SCC1=CC=C(NC(C)=O)C=C1 HUTRBWHPRNSUPR-UHFFFAOYSA-N 0.000 claims 1
• VBJYGQCRTQZHKS-UHFFFAOYSA-N N-[4-[5-[(2-chlorophenyl)methylsulfanyl]-4-methyl-1,2,4-triazol-3-yl]phenyl]-2-methoxybenzamide Chemical compound COC1=CC=CC=C1C(=O)NC1=CC=C(C=2N(C(SCC=3C(=CC=CC=3)Cl)=NN=2)C)C=C1 VBJYGQCRTQZHKS-UHFFFAOYSA-N 0.000 claims 1
• DYOAMVROJXEOQS-UHFFFAOYSA-N N-[4-[[4-ethyl-5-(1H-indol-3-ylmethyl)-1,2,4-triazol-3-yl]sulfanylmethyl]phenyl]acetamide Chemical compound CCN1C(CC=2C3=CC=CC=C3NC=2)=NN=C1SCC1=CC=C(NC(C)=O)C=C1 DYOAMVROJXEOQS-UHFFFAOYSA-N 0.000 claims 1
• AXVKLGAEWBEFDB-UHFFFAOYSA-N N-[4-[[4-ethyl-5-(2-methylsulfanylpyridin-3-yl)-1,2,4-triazol-3-yl]sulfanylmethyl]phenyl]acetamide Chemical compound N=1N=C(C=2C(=NC=CC=2)SC)N(CC)C=1SCC1=CC=C(NC(C)=O)C=C1 AXVKLGAEWBEFDB-UHFFFAOYSA-N 0.000 claims 1
• UPSKOXRXTUPEGP-UHFFFAOYSA-N N-[4-[[4-ethyl-5-(3-hydroxypropyl)-1,2,4-triazol-3-yl]sulfanylmethyl]phenyl]acetamide Chemical compound CCN1C(CCCO)=NN=C1SCC1=CC=C(NC(C)=O)C=C1 UPSKOXRXTUPEGP-UHFFFAOYSA-N 0.000 claims 1
• MKIPALOJKHNPBZ-UHFFFAOYSA-N N-[4-[[4-ethyl-5-(4-methoxyphenyl)-1,2,4-triazol-3-yl]sulfanylmethyl]phenyl]acetamide Chemical compound N=1N=C(C=2C=CC(OC)=CC=2)N(CC)C=1SCC1=CC=C(NC(C)=O)C=C1 MKIPALOJKHNPBZ-UHFFFAOYSA-N 0.000 claims 1
• TXSPMALGFZQOHA-UHFFFAOYSA-N N-[4-[[4-ethyl-5-(5-methylthiophen-2-yl)-1,2,4-triazol-3-yl]sulfanylmethyl]phenyl]acetamide Chemical compound N=1N=C(C=2SC(C)=CC=2)N(CC)C=1SCC1=CC=C(NC(C)=O)C=C1 TXSPMALGFZQOHA-UHFFFAOYSA-N 0.000 claims 1
• IUXSXJFKIRAFRC-UHFFFAOYSA-N N-[4-[[4-ethyl-5-[1-phenyl-5-(trifluoromethyl)pyrazol-4-yl]-1,2,4-triazol-3-yl]sulfanylmethyl]phenyl]acetamide Chemical compound N=1N=C(C2=C(N(N=C2)C=2C=CC=CC=2)C(F)(F)F)N(CC)C=1SCC1=CC=C(NC(C)=O)C=C1 IUXSXJFKIRAFRC-UHFFFAOYSA-N 0.000 claims 1
• SOJQRABDNRLSEX-UHFFFAOYSA-N N-[4-[[5-(1,3-benzodioxol-5-yl)-4-ethyl-1,2,4-triazol-3-yl]sulfanylmethyl]phenyl]acetamide Chemical compound N=1N=C(C=2C=C3OCOC3=CC=2)N(CC)C=1SCC1=CC=C(NC(C)=O)C=C1 SOJQRABDNRLSEX-UHFFFAOYSA-N 0.000 claims 1
• QTFZZTQNLNYSEX-UHFFFAOYSA-N N-[4-[[5-(1-benzothiophen-2-yl)-4-ethyl-1,2,4-triazol-3-yl]sulfanylmethyl]phenyl]acetamide Chemical compound N=1N=C(C=2SC3=CC=CC=C3C=2)N(CC)C=1SCC1=CC=C(NC(C)=O)C=C1 QTFZZTQNLNYSEX-UHFFFAOYSA-N 0.000 claims 1
• GBNZHSRQJXVCGI-UHFFFAOYSA-N N-[4-[[5-(4-chlorophenyl)-4-ethyl-1,2,4-triazol-3-yl]sulfanylmethyl]phenyl]acetamide Chemical compound N=1N=C(C=2C=CC(Cl)=CC=2)N(CC)C=1SCC1=CC=C(NC(C)=O)C=C1 GBNZHSRQJXVCGI-UHFFFAOYSA-N 0.000 claims 1
• SYWCOHKGECVQPI-UHFFFAOYSA-N N-[4-[[5-(5-chlorothiophen-2-yl)-4-ethyl-1,2,4-triazol-3-yl]sulfanylmethyl]phenyl]acetamide Chemical compound N=1N=C(C=2SC(Cl)=CC=2)N(CC)C=1SCC1=CC=C(NC(C)=O)C=C1 SYWCOHKGECVQPI-UHFFFAOYSA-N 0.000 claims 1
• JFLDRUSVKJSDFM-UHFFFAOYSA-N N-[4-[[5-[4-(2,5-dimethylpyrrol-1-yl)phenyl]-4-ethyl-1,2,4-triazol-3-yl]sulfanylmethyl]phenyl]acetamide Chemical compound N=1N=C(C=2C=CC(=CC=2)N2C(=CC=C2C)C)N(CC)C=1SCC1=CC=C(NC(C)=O)C=C1 JFLDRUSVKJSDFM-UHFFFAOYSA-N 0.000 claims 1
• ZMMXAQZVRTZPKF-UHFFFAOYSA-N N-[4-[benzyl(propan-2-yl)sulfamoyl]phenyl]acetamide Chemical compound C=1C=C(NC(C)=O)C=CC=1S(=O)(=O)N(C(C)C)CC1=CC=CC=C1 ZMMXAQZVRTZPKF-UHFFFAOYSA-N 0.000 claims 1
• IOOQRTGQTISKGP-UHFFFAOYSA-N N-[5-(5-chloro-1,3-benzoxazol-2-yl)-2-methylphenyl]-2-methoxybenzamide Chemical compound COC1=CC=CC=C1C(=O)NC1=CC(C=2OC3=CC=C(Cl)C=C3N=2)=CC=C1C IOOQRTGQTISKGP-UHFFFAOYSA-N 0.000 claims 1
• FIGDPVVDJQSDSB-UHFFFAOYSA-N N-[5-[(2,4-dichlorophenyl)methylsulfanyl]-1,3,4-thiadiazol-2-yl]-2,2-dimethylpropanamide Chemical compound S1C(NC(=O)C(C)(C)C)=NN=C1SCC1=CC=C(Cl)C=C1Cl FIGDPVVDJQSDSB-UHFFFAOYSA-N 0.000 claims 1
• XMPPBIXEZQVXGO-UHFFFAOYSA-N N-[5-[(2-fluorophenyl)methylsulfanylmethyl]-1,3,4-thiadiazol-2-yl]cyclohexanecarboxamide Chemical compound FC1=CC=CC=C1CSCC(S1)=NN=C1NC(=O)C1CCCCC1 XMPPBIXEZQVXGO-UHFFFAOYSA-N 0.000 claims 1
• ZHKFMACOXDAWLY-UHFFFAOYSA-N N-[5-[(3,4-dichlorophenyl)methyl]-1,3,4-thiadiazol-2-yl]-2,2-dimethylpropanamide Chemical compound S1C(NC(=O)C(C)(C)C)=NN=C1CC1=CC=C(Cl)C(Cl)=C1 ZHKFMACOXDAWLY-UHFFFAOYSA-N 0.000 claims 1
• JUGGVFGUZJIERO-UHFFFAOYSA-N N-[5-[(3,4-dimethoxyphenyl)methyl]-1,3,4-thiadiazol-2-yl]-3-methylbutanamide Chemical compound C1=C(OC)C(OC)=CC=C1CC1=NN=C(NC(=O)CC(C)C)S1 JUGGVFGUZJIERO-UHFFFAOYSA-N 0.000 claims 1
• RGBKRAVLDSEOGW-UHFFFAOYSA-N N-[6-(2,6-difluorophenoxy)hexyl]-4-(trifluoromethyl)cyclohexane-1-carboxamide Chemical compound FC1=CC=CC(F)=C1OCCCCCCNC(=O)C1CCC(C(F)(F)F)CC1 RGBKRAVLDSEOGW-UHFFFAOYSA-N 0.000 claims 1
• JTAJDRPNOSMJDJ-UHFFFAOYSA-N N-[[2-[(4-fluorophenyl)methylamino]-1,3-thiazol-4-yl]methyl]-N-(2-phenylethyl)butanamide Chemical compound C=1SC(NCC=2C=CC(F)=CC=2)=NC=1CN(C(=O)CCC)CCC1=CC=CC=C1 JTAJDRPNOSMJDJ-UHFFFAOYSA-N 0.000 claims 1
• PEOPQRYUIQSKSG-UHFFFAOYSA-N N-[[4-(3,4-dihydro-1H-isoquinoline-2-carbonyl)phenyl]methyl]-N-(3,4-dimethylphenyl)methanesulfonamide Chemical compound C1=C(C)C(C)=CC=C1N(S(C)(=O)=O)CC1=CC=C(C(=O)N2CC3=CC=CC=C3CC2)C=C1 PEOPQRYUIQSKSG-UHFFFAOYSA-N 0.000 claims 1
• WPDJDHRXHNJFKD-UHFFFAOYSA-N N-[[4-(trifluoromethyl)phenyl]methyl]-5-(3,3,5-trimethyl-7-azabicyclo[3.2.1]octane-7-carbonyl)-1H-indole-3-carboxamide Chemical compound C1C(C)(C)CC(C)(C2)CC1N2C(=O)C(C=C12)=CC=C1NC=C2C(=O)NCC1=CC=C(C(F)(F)F)C=C1 WPDJDHRXHNJFKD-UHFFFAOYSA-N 0.000 claims 1
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• LWYNCCMTLFTBKO-UHFFFAOYSA-N N-[[4-ethyl-5-[(4-nitrophenyl)methylsulfanyl]-1,2,4-triazol-3-yl]methyl]-2,4-dimethylaniline Chemical compound N=1N=C(SCC=2C=CC(=CC=2)[N+]([O-])=O)N(CC)C=1CNC1=CC=C(C)C=C1C LWYNCCMTLFTBKO-UHFFFAOYSA-N 0.000 claims 1
• JXGCCLJJGJZRFO-UHFFFAOYSA-N N-[[5-[(4-chlorophenyl)methylsulfanyl]-4-ethyl-1,2,4-triazol-3-yl]methyl]-4-fluoroaniline Chemical compound N=1N=C(SCC=2C=CC(Cl)=CC=2)N(CC)C=1CNC1=CC=C(F)C=C1 JXGCCLJJGJZRFO-UHFFFAOYSA-N 0.000 claims 1
• KNBPLLSBSOIZCV-UHFFFAOYSA-N N-[[5-[(4-tert-butylphenyl)methylsulfanyl]-4-methyl-1,2,4-triazol-3-yl]methyl]-4-methylbenzenesulfonamide Chemical compound C1=CC(C)=CC=C1S(=O)(=O)NCC(N1C)=NN=C1SCC1=CC=C(C(C)(C)C)C=C1 KNBPLLSBSOIZCV-UHFFFAOYSA-N 0.000 claims 1
• IHRIRTAQBFITOO-UHFFFAOYSA-N N-[[5-[2-[3,5-bis(4-methoxyphenyl)-3,4-dihydropyrazol-2-yl]-2-oxoethyl]sulfanyl-4-methyl-1,2,4-triazol-3-yl]methyl]-3-methoxybenzamide Chemical compound C1=CC(OC)=CC=C1C1N(C(=O)CSC=2N(C(CNC(=O)C=3C=C(OC)C=CC=3)=NN=2)C)N=C(C=2C=CC(OC)=CC=2)C1 IHRIRTAQBFITOO-UHFFFAOYSA-N 0.000 claims 1
• GBXRIONXERFQKT-UHFFFAOYSA-N N-[[5-[2-[3-(4-methoxyphenyl)-5-thiophen-2-yl-3,4-dihydropyrazol-2-yl]-2-oxoethyl]sulfanyl-4-methyl-1,2,4-triazol-3-yl]methyl]-4-morpholin-4-ylsulfonylbenzamide Chemical compound C1=CC(OC)=CC=C1C1N(C(=O)CSC=2N(C(CNC(=O)C=3C=CC(=CC=3)S(=O)(=O)N3CCOCC3)=NN=2)C)N=C(C=2SC=CC=2)C1 GBXRIONXERFQKT-UHFFFAOYSA-N 0.000 claims 1
• VPACQFVUNBXRSY-UHFFFAOYSA-N N-[[5-[2-[3-(4-methoxyphenyl)-5-thiophen-2-yl-3,4-dihydropyrazol-2-yl]-2-oxoethyl]sulfanyl-4-methyl-1,2,4-triazol-3-yl]methyl]-4-piperidin-1-ylsulfonylbenzamide Chemical compound C1=CC(OC)=CC=C1C1N(C(=O)CSC=2N(C(CNC(=O)C=3C=CC(=CC=3)S(=O)(=O)N3CCCCC3)=NN=2)C)N=C(C=2SC=CC=2)C1 VPACQFVUNBXRSY-UHFFFAOYSA-N 0.000 claims 1
• ZVPVUBGUTYYBPG-UHFFFAOYSA-N N-[[5-[2-[3-(4-methoxyphenyl)-5-thiophen-2-yl-3,4-dihydropyrazol-2-yl]-2-oxoethyl]sulfanyl-4-methyl-1,2,4-triazol-3-yl]methyl]-4-pyrrolidin-1-ylsulfonylbenzamide Chemical compound C1=CC(OC)=CC=C1C1N(C(=O)CSC=2N(C(CNC(=O)C=3C=CC(=CC=3)S(=O)(=O)N3CCCC3)=NN=2)C)N=C(C=2SC=CC=2)C1 ZVPVUBGUTYYBPG-UHFFFAOYSA-N 0.000 claims 1
• UWLUGCSIAPHEKH-UHFFFAOYSA-N N-[[5-[2-[3-(4-methoxyphenyl)-5-thiophen-2-yl-3,4-dihydropyrazol-2-yl]-2-oxoethyl]sulfanyl-4-methyl-1,2,4-triazol-3-yl]methyl]benzamide Chemical compound C1=CC(OC)=CC=C1C1N(C(=O)CSC=2N(C(CNC(=O)C=3C=CC=CC=3)=NN=2)C)N=C(C=2SC=CC=2)C1 UWLUGCSIAPHEKH-UHFFFAOYSA-N 0.000 claims 1
• YFOQQGPVQCOXPU-UHFFFAOYSA-N N-benzyl-2,4-dichloro-N-(1-cyclopropylethyl)-5-methylbenzamide Chemical compound C=1C=CC=CC=1CN(C(=O)C=1C(=CC(Cl)=C(C)C=1)Cl)C(C)C1CC1 YFOQQGPVQCOXPU-UHFFFAOYSA-N 0.000 claims 1
• YTGGACXECZKQDI-UHFFFAOYSA-N N-benzyl-2,4-dichloro-N-methylbenzamide Chemical compound C=1C=C(Cl)C=C(Cl)C=1C(=O)N(C)CC1=CC=CC=C1 YTGGACXECZKQDI-UHFFFAOYSA-N 0.000 claims 1
• IICRGELEDGGGDE-UHFFFAOYSA-N N-benzyl-2,4-dichloro-N-pyridin-2-ylbenzamide Chemical compound ClC1=CC(Cl)=CC=C1C(=O)N(C=1N=CC=CC=1)CC1=CC=CC=C1 IICRGELEDGGGDE-UHFFFAOYSA-N 0.000 claims 1
• GODIPIVUYYDCMJ-UHFFFAOYSA-N N-benzyl-2-(4-chlorophenyl)sulfanyl-N-methylacetamide Chemical compound C=1C=C(Cl)C=CC=1SCC(=O)N(C)CC1=CC=CC=C1 GODIPIVUYYDCMJ-UHFFFAOYSA-N 0.000 claims 1
• MHAJOKPDLPBLAO-UHFFFAOYSA-N N-benzyl-2-[4,4,6-trimethyl-1-(4-methylphenyl)pyrimidin-2-yl]sulfanylacetamide Chemical compound C=1C=C(C)C=CC=1N1C(C)=CC(C)(C)N=C1SCC(=O)NCC1=CC=CC=C1 MHAJOKPDLPBLAO-UHFFFAOYSA-N 0.000 claims 1
• CGYAEGNOMBJVDQ-UHFFFAOYSA-N N-benzyl-2-bromo-N-methylbenzamide Chemical compound C=1C=CC=C(Br)C=1C(=O)N(C)CC1=CC=CC=C1 CGYAEGNOMBJVDQ-UHFFFAOYSA-N 0.000 claims 1
• NHXZKFPAKHXJDK-UHFFFAOYSA-N N-benzyl-2-bromo-N-propan-2-ylbenzamide Chemical compound C=1C=CC=C(Br)C=1C(=O)N(C(C)C)CC1=CC=CC=C1 NHXZKFPAKHXJDK-UHFFFAOYSA-N 0.000 claims 1
• INYHTXZCWGKMOL-UHFFFAOYSA-N N-benzyl-3-(3,3,5-trimethyl-7-azabicyclo[3.2.1]octane-7-carbonyl)benzenesulfonamide Chemical compound C1C(C)(C)CC(C)(C2)CC1N2C(=O)C(C=1)=CC=CC=1S(=O)(=O)NCC1=CC=CC=C1 INYHTXZCWGKMOL-UHFFFAOYSA-N 0.000 claims 1
• JJGVEPLALDHXCZ-UHFFFAOYSA-N N-benzyl-3-methyl-4-(4-methylphenyl)butanamide Chemical compound C=1C=C(C)C=CC=1CC(C)CC(=O)NCC1=CC=CC=C1 JJGVEPLALDHXCZ-UHFFFAOYSA-N 0.000 claims 1
• RGGCHKVBJKBTEF-UHFFFAOYSA-N N-benzyl-4-bromo-N-ethylbenzamide Chemical compound C=1C=C(Br)C=CC=1C(=O)N(CC)CC1=CC=CC=C1 RGGCHKVBJKBTEF-UHFFFAOYSA-N 0.000 claims 1
• NGZSJSBJVCIBDV-UHFFFAOYSA-N N-benzyl-4-chloro-3-nitro-N-propan-2-ylbenzamide Chemical compound C=1C=C(Cl)C([N+]([O-])=O)=CC=1C(=O)N(C(C)C)CC1=CC=CC=C1 NGZSJSBJVCIBDV-UHFFFAOYSA-N 0.000 claims 1
• LVOYLMZXCRBAER-UHFFFAOYSA-N N-benzyl-4-chloro-N-(1-cyclopropylethenyl)benzamide Chemical compound C1=CC(Cl)=CC=C1C(=O)N(C(=C)C1CC1)CC1=CC=CC=C1 LVOYLMZXCRBAER-UHFFFAOYSA-N 0.000 claims 1
• XIDDYQJNFNIUNM-UHFFFAOYSA-N N-benzyl-4-methyl-3-nitro-N-propan-2-ylbenzamide Chemical compound C=1C=C(C)C([N+]([O-])=O)=CC=1C(=O)N(C(C)C)CC1=CC=CC=C1 XIDDYQJNFNIUNM-UHFFFAOYSA-N 0.000 claims 1
• WOIOOHBTONFDSI-UHFFFAOYSA-N N-benzyl-4-nitro-N-propan-2-ylbenzamide Chemical compound C=1C=C([N+]([O-])=O)C=CC=1C(=O)N(C(C)C)CC1=CC=CC=C1 WOIOOHBTONFDSI-UHFFFAOYSA-N 0.000 claims 1
• POKNIDHFUWCRAD-UHFFFAOYSA-N N-benzyl-5-(3,3,5-trimethyl-7-azabicyclo[3.2.1]octane-7-carbonyl)-1H-indole-3-carboxamide Chemical compound C1C(C)(C)CC(C)(C2)CC1N2C(=O)C(C=C12)=CC=C1NC=C2C(=O)NCC1=CC=CC=C1 POKNIDHFUWCRAD-UHFFFAOYSA-N 0.000 claims 1
• UNWUKCQLINQLAH-UHFFFAOYSA-N N-benzyl-7-(difluoromethyl)-N-methyl-5-(4-methylphenyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide Chemical compound C1=NN2C(C(F)F)=CC(C=3C=CC(C)=CC=3)=NC2=C1C(=O)N(C)CC1=CC=CC=C1 UNWUKCQLINQLAH-UHFFFAOYSA-N 0.000 claims 1
• YTQFPSJHEQWCIE-UHFFFAOYSA-N N-benzyl-N,3,4-trimethylbenzamide Chemical compound C=1C=C(C)C(C)=CC=1C(=O)N(C)CC1=CC=CC=C1 YTQFPSJHEQWCIE-UHFFFAOYSA-N 0.000 claims 1
• MSWJDGFXYUCOGB-UHFFFAOYSA-N N-benzyl-N,4-dimethylbenzamide Chemical compound C=1C=C(C)C=CC=1C(=O)N(C)CC1=CC=CC=C1 MSWJDGFXYUCOGB-UHFFFAOYSA-N 0.000 claims 1
• XGFAPUQEUDMPLY-UHFFFAOYSA-N N-benzyl-N,7-dimethyl-5-phenylpyrazolo[1,5-a]pyrimidine-2-carboxamide Chemical compound C1=C2N=C(C=3C=CC=CC=3)C=C(C)N2N=C1C(=O)N(C)CC1=CC=CC=C1 XGFAPUQEUDMPLY-UHFFFAOYSA-N 0.000 claims 1
• NRJXPCVXNPNZEQ-UHFFFAOYSA-N N-benzyl-N-(1-cyclopropylethyl)-4-fluorobenzamide Chemical compound C=1C=CC=CC=1CN(C(=O)C=1C=CC(F)=CC=1)C(C)C1CC1 NRJXPCVXNPNZEQ-UHFFFAOYSA-N 0.000 claims 1
• CQQMWVSZEXOCFU-UHFFFAOYSA-N N-benzyl-N-(2-hydroxyethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide Chemical compound C1=NN2C=CC=NC2=C1C(=O)N(CCO)CC1=CC=CC=C1 CQQMWVSZEXOCFU-UHFFFAOYSA-N 0.000 claims 1
• ILLIYROTTPZHTB-UHFFFAOYSA-N N-benzyl-N-(2-oxo-2-pyrrolidin-1-ylethyl)benzenesulfonamide Chemical compound C1CCCN1C(=O)CN(S(=O)(=O)C=1C=CC=CC=1)CC1=CC=CC=C1 ILLIYROTTPZHTB-UHFFFAOYSA-N 0.000 claims 1
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• QDZLFLIZEDLIFV-UHFFFAOYSA-N N-benzyl-N-(cyclohexen-1-yl)pyridine-4-carboxamide Chemical compound C=1C=NC=CC=1C(=O)N(C=1CCCCC=1)CC1=CC=CC=C1 QDZLFLIZEDLIFV-UHFFFAOYSA-N 0.000 claims 1
• XPDFCFPJQDYGEQ-UHFFFAOYSA-N N-benzyl-N-[2-oxo-2-(4-phenylpiperazin-1-yl)ethyl]benzenesulfonamide Chemical compound C1CN(C=2C=CC=CC=2)CCN1C(=O)CN(S(=O)(=O)C=1C=CC=CC=1)CC1=CC=CC=C1 XPDFCFPJQDYGEQ-UHFFFAOYSA-N 0.000 claims 1
• DATREZAFTMCHQA-UHFFFAOYSA-N N-benzyl-N-ethyl-2-phenylacetamide Chemical compound C=1C=CC=CC=1CC(=O)N(CC)CC1=CC=CC=C1 DATREZAFTMCHQA-UHFFFAOYSA-N 0.000 claims 1
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• ZJSWTFDCYDLVHN-UHFFFAOYSA-N N-benzyl-N-methyl-5,7-diphenylpyrazolo[1,5-a]pyrimidine-2-carboxamide Chemical compound C1=C2N=C(C=3C=CC=CC=3)C=C(C=3C=CC=CC=3)N2N=C1C(=O)N(C)CC1=CC=CC=C1 ZJSWTFDCYDLVHN-UHFFFAOYSA-N 0.000 claims 1
• NFXCDSGIARGWGR-UHFFFAOYSA-N N-benzyl-N-methyl-5-phenyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide Chemical compound C1=C2N=C(C=3C=CC=CC=3)C=C(C(F)(F)F)N2N=C1C(=O)N(C)CC1=CC=CC=C1 NFXCDSGIARGWGR-UHFFFAOYSA-N 0.000 claims 1
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• LKLFNWAQJYRLDW-UHFFFAOYSA-N N-benzyl-N-pyridin-2-yladamantane-1-carboxamide Chemical compound C1C(C2)CC(C3)CC2CC13C(=O)N(C=1N=CC=CC=1)CC1=CC=CC=C1 LKLFNWAQJYRLDW-UHFFFAOYSA-N 0.000 claims 1
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• KKQPEQCDXJAEJO-UHFFFAOYSA-N N-cyclobutyl-N-[(4-hydroxyphenyl)methyl]-4-(trifluoromethyl)benzamide Chemical compound C1=CC(O)=CC=C1CN(C(=O)C=1C=CC(=CC=1)C(F)(F)F)C1CCC1 KKQPEQCDXJAEJO-UHFFFAOYSA-N 0.000 claims 1
• OWFCGQWRNAEAQG-UHFFFAOYSA-N N-cycloheptyl-1-methylindole-3-carboxamide Chemical compound C12=CC=CC=C2N(C)C=C1C(=O)NC1CCCCCC1 OWFCGQWRNAEAQG-UHFFFAOYSA-N 0.000 claims 1
• UJNGUUOZULFJAN-UHFFFAOYSA-N N-cycloheptyl-2,4-dimethoxybenzamide Chemical compound COC1=CC(OC)=CC=C1C(=O)NC1CCCCCC1 UJNGUUOZULFJAN-UHFFFAOYSA-N 0.000 claims 1
• JJKHZGHDEUCSQD-UHFFFAOYSA-N N-cycloheptyl-2,4-dimethyl-1,3-thiazole-5-carboxamide Chemical compound S1C(C)=NC(C)=C1C(=O)NC1CCCCCC1 JJKHZGHDEUCSQD-UHFFFAOYSA-N 0.000 claims 1
• JWORJSFJAYFGSP-UHFFFAOYSA-N N-cycloheptyl-2-(2,6-dimethylphenoxy)acetamide Chemical compound CC1=CC=CC(C)=C1OCC(=O)NC1CCCCCC1 JWORJSFJAYFGSP-UHFFFAOYSA-N 0.000 claims 1
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• QFZZIDSFNDMMML-UHFFFAOYSA-N N-cycloheptyl-5-[(2-methoxyphenoxy)methyl]furan-2-carboxamide Chemical compound COC1=CC=CC=C1OCC1=CC=C(C(=O)NC2CCCCCC2)O1 QFZZIDSFNDMMML-UHFFFAOYSA-N 0.000 claims 1
• ZTNWPEYXPVDTFM-UHFFFAOYSA-N N-cycloheptyl-N-methyl-2-(phenoxymethyl)benzamide Chemical compound C=1C=CC=C(COC=2C=CC=CC=2)C=1C(=O)N(C)C1CCCCCC1 ZTNWPEYXPVDTFM-UHFFFAOYSA-N 0.000 claims 1
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• WGZBBYGXEPVIHQ-UHFFFAOYSA-N N-cyclohexyl-1-(4-fluorophenyl)-N,5-dimethylpyrazole-4-carboxamide Chemical compound C1=NN(C=2C=CC(F)=CC=2)C(C)=C1C(=O)N(C)C1CCCCC1 WGZBBYGXEPVIHQ-UHFFFAOYSA-N 0.000 claims 1
• LFTLSRXZDFSOIX-UHFFFAOYSA-N N-cyclohexyl-1-(4-methoxyphenyl)-N,5-dimethylpyrazole-4-carboxamide Chemical compound C1=CC(OC)=CC=C1N1C(C)=C(C(=O)N(C)C2CCCCC2)C=N1 LFTLSRXZDFSOIX-UHFFFAOYSA-N 0.000 claims 1
• YOFNWFOOKXAPNR-UHFFFAOYSA-N N-cyclohexyl-2-(1,3-dioxoisoindol-2-yl)-3-phenylpropanamide Chemical compound C=1C=CC=CC=1CC(N1C(C2=CC=CC=C2C1=O)=O)C(=O)NC1CCCCC1 YOFNWFOOKXAPNR-UHFFFAOYSA-N 0.000 claims 1
• WBUIJFFZJWYWIB-UHFFFAOYSA-N N-cyclohexyl-2-(2,3-dimethoxyphenoxy)-N-methylbenzamide Chemical compound COC1=CC=CC(OC=2C(=CC=CC=2)C(=O)N(C)C2CCCCC2)=C1OC WBUIJFFZJWYWIB-UHFFFAOYSA-N 0.000 claims 1
• UGMSZGHQNFFWCB-UHFFFAOYSA-N N-cyclohexyl-2-(3,5-dimethoxyphenoxy)-N-methylbenzamide Chemical compound COC1=CC(OC)=CC(OC=2C(=CC=CC=2)C(=O)N(C)C2CCCCC2)=C1 UGMSZGHQNFFWCB-UHFFFAOYSA-N 0.000 claims 1
• XPOWDUUIYHDBKF-UHFFFAOYSA-N N-cyclohexyl-2-(hydroxymethyl)-N-methyl-3H-benzimidazole-5-carboxamide Chemical compound C=1C=C2NC(CO)=NC2=CC=1C(=O)N(C)C1CCCCC1 XPOWDUUIYHDBKF-UHFFFAOYSA-N 0.000 claims 1
• MDMJDAFJWGZBGA-UHFFFAOYSA-N N-cyclohexyl-2-[(4-ethyl-5-phenyl-1,2,4-triazol-3-yl)sulfanyl]-N-methylacetamide Chemical compound N=1N=C(C=2C=CC=CC=2)N(CC)C=1SCC(=O)N(C)C1CCCCC1 MDMJDAFJWGZBGA-UHFFFAOYSA-N 0.000 claims 1
• LHFQKONQPPTITE-UHFFFAOYSA-N N-cyclohexyl-2-[[4-(2-phenylethyl)-5-pyridin-3-yl-1,2,4-triazol-3-yl]sulfanyl]acetamide Chemical compound C1CCCCC1NC(=O)CSC(N1CCC=2C=CC=CC=2)=NN=C1C1=CC=CN=C1 LHFQKONQPPTITE-UHFFFAOYSA-N 0.000 claims 1
• CZBJNAZRHZAZOF-UHFFFAOYSA-N N-cyclohexyl-2-hydroxy-N-methylbenzamide Chemical compound C=1C=CC=C(O)C=1C(=O)N(C)C1CCCCC1 CZBJNAZRHZAZOF-UHFFFAOYSA-N 0.000 claims 1
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• OMEFIYTYZJNWPR-UHFFFAOYSA-N [1-(4-chlorophenyl)-5-propylpyrazol-4-yl]-(3,3,5-trimethyl-7-azabicyclo[3.2.1]octan-7-yl)methanone Chemical compound CCCC1=C(C(=O)N2C3CC(CC(C)(C)C3)(C)C2)C=NN1C1=CC=C(Cl)C=C1 OMEFIYTYZJNWPR-UHFFFAOYSA-N 0.000 claims 1
• RQRGRZOOHVSAGT-UHFFFAOYSA-N [1-(4-methoxyphenyl)-5-methylpyrazol-4-yl]-(3,3,5-trimethyl-7-azabicyclo[3.2.1]octan-7-yl)methanone Chemical compound C1=CC(OC)=CC=C1N1C(C)=C(C(=O)N2C3CC(CC(C)(C)C3)(C)C2)C=N1 RQRGRZOOHVSAGT-UHFFFAOYSA-N 0.000 claims 1
• KZFWDKNBWPNAMF-UHFFFAOYSA-N [1-(6-methylpyridin-2-yl)imidazol-4-yl]-(3,3,5-trimethyl-7-azabicyclo[3.2.1]octan-7-yl)methanone Chemical compound CC1=CC=CC(N2C=C(N=C2)C(=O)N2C3CC(CC(C)(C)C3)(C)C2)=N1 KZFWDKNBWPNAMF-UHFFFAOYSA-N 0.000 claims 1
• JDRVHARCLYLPLM-UHFFFAOYSA-N [1-(benzenesulfonyl)-2-methylindol-5-yl]-(3,3,5-trimethyl-7-azabicyclo[3.2.1]octan-7-yl)methanone Chemical compound CC1=CC2=CC(C(=O)N3C4CC(CC(C)(C)C4)(C)C3)=CC=C2N1S(=O)(=O)C1=CC=CC=C1 JDRVHARCLYLPLM-UHFFFAOYSA-N 0.000 claims 1
• ITHMMSJQNHCBBD-UHFFFAOYSA-N [1-(benzenesulfonyl)indol-5-yl]-(3,3,5-trimethyl-7-azabicyclo[3.2.1]octan-7-yl)methanone Chemical compound C1C(C)(C)CC(C)(C2)CC1N2C(=O)C(C=C1C=C2)=CC=C1N2S(=O)(=O)C1=CC=CC=C1 ITHMMSJQNHCBBD-UHFFFAOYSA-N 0.000 claims 1
• PDUYGZRQLUOFAU-UHFFFAOYSA-N [1-(benzenesulfonyl)piperidin-3-yl]-(3,4-dihydro-1H-isoquinolin-2-yl)methanone Chemical compound C1CC2=CC=CC=C2CN1C(=O)C(C1)CCCN1S(=O)(=O)C1=CC=CC=C1 PDUYGZRQLUOFAU-UHFFFAOYSA-N 0.000 claims 1
• AETDCZYSSKFPOT-UHFFFAOYSA-N [1-(cyclopropylmethyl)-6-fluoroindol-3-yl]-(3,3,5-trimethyl-7-azabicyclo[3.2.1]octan-7-yl)methanone Chemical compound C1C(C)(C)CC(C)(C2)CC1N2C(=O)C(C1=CC=C(F)C=C11)=CN1CC1CC1 AETDCZYSSKFPOT-UHFFFAOYSA-N 0.000 claims 1
• NSKXYDRKDPRQRI-UHFFFAOYSA-N [1-(oxolan-2-ylmethyl)indol-5-yl]-(3,3,5-trimethyl-7-azabicyclo[3.2.1]octan-7-yl)methanone Chemical compound C1C(C)(C)CC(C)(C2)CC1N2C(=O)C(C=C1C=C2)=CC=C1N2CC1CCCO1 NSKXYDRKDPRQRI-UHFFFAOYSA-N 0.000 claims 1
• FWORSSYSVONBFV-UHFFFAOYSA-N [1-[[4-(trifluoromethoxy)phenyl]methyl]indol-5-yl]-(3,3,5-trimethyl-7-azabicyclo[3.2.1]octan-7-yl)methanone Chemical compound C1C(C)(C)CC(C)(C2)CC1N2C(=O)C(C=C1C=C2)=CC=C1N2CC1=CC=C(OC(F)(F)F)C=C1 FWORSSYSVONBFV-UHFFFAOYSA-N 0.000 claims 1
• ZBWCXACGUVQGDW-UHFFFAOYSA-N [2-(1,3-benzodioxol-5-yl)-3H-benzimidazol-5-yl]-(3,3,5-trimethyl-7-azabicyclo[3.2.1]octan-7-yl)methanone Chemical compound C1=C2OCOC2=CC(C=2NC3=CC=C(C=C3N=2)C(=O)N2C3CC(CC(C)(C)C3)(C2)C)=C1 ZBWCXACGUVQGDW-UHFFFAOYSA-N 0.000 claims 1
• SRVUADGOBORSOL-UHFFFAOYSA-N [2-(2-nitrophenyl)-3H-benzimidazol-5-yl]-(3,3,5-trimethyl-7-azabicyclo[3.2.1]octan-7-yl)methanone Chemical compound C1C(C)(C)CC(C)(C2)CC1N2C(=O)C(C=C1N=2)=CC=C1NC=2C1=CC=CC=C1[N+]([O-])=O SRVUADGOBORSOL-UHFFFAOYSA-N 0.000 claims 1
• WMUVQWLPJIFRAV-UHFFFAOYSA-N [2-(4-methylphenyl)sulfanylphenyl]-(4-methylpiperazin-1-yl)methanone Chemical compound C1CN(C)CCN1C(=O)C1=CC=CC=C1SC1=CC=C(C)C=C1 WMUVQWLPJIFRAV-UHFFFAOYSA-N 0.000 claims 1
• MVXMAYWZYMUVRX-UHFFFAOYSA-N [2-(phenoxymethyl)phenyl]-(3,3,5-trimethyl-7-azabicyclo[3.2.1]octan-7-yl)methanone Chemical compound C1C(C)(C)CC(C)(C2)CC1N2C(=O)C1=CC=CC=C1COC1=CC=CC=C1 MVXMAYWZYMUVRX-UHFFFAOYSA-N 0.000 claims 1
• FKAXCHIUYWEAHJ-UHFFFAOYSA-N [3-(1,3-thiazol-2-yl)-1H-indol-5-yl]-(3,3,5-trimethyl-7-azabicyclo[3.2.1]octan-7-yl)methanone Chemical compound C1C(C)(C)CC(C)(C2)CC1N2C(=O)C(C=C12)=CC=C1NC=C2C1=NC=CS1 FKAXCHIUYWEAHJ-UHFFFAOYSA-N 0.000 claims 1
• DFFWGHYCZYQSDN-UHFFFAOYSA-N [3-(2,3-dihydroindol-1-ylsulfonyl)phenyl]-(3,4-dihydro-2H-quinolin-1-yl)methanone Chemical compound C1CC2=CC=CC=C2N1S(=O)(=O)C1=CC(C(N2C3=CC=CC=C3CCC2)=O)=CC=C1 DFFWGHYCZYQSDN-UHFFFAOYSA-N 0.000 claims 1
• WRMDCWRIXINKQX-UHFFFAOYSA-N [3-(2,5-dimethylpyrrol-1-yl)phenyl]-(4-methylpiperidin-1-yl)methanone Chemical compound C1CC(C)CCN1C(=O)C1=CC=CC(N2C(=CC=C2C)C)=C1 WRMDCWRIXINKQX-UHFFFAOYSA-N 0.000 claims 1
• INKHCEQTAQTFEJ-UHFFFAOYSA-N [3-(2-chloro-6-nitrophenoxy)phenyl]-piperidin-1-ylmethanone Chemical compound [O-][N+](=O)C1=CC=CC(Cl)=C1OC1=CC=CC(C(=O)N2CCCCC2)=C1 INKHCEQTAQTFEJ-UHFFFAOYSA-N 0.000 claims 1
• QNSCIZRHXLLGBB-UHFFFAOYSA-N [3-(3,3,5-trimethyl-7-azabicyclo[3.2.1]octane-7-carbonyl)-1H-indol-5-yl]-(3,3,5-trimethyl-7-azabicyclo[3.2.1]octan-7-yl)methanone Chemical compound C1C(CC(C)(C)C2)(C)CC2N1C(=O)C(C=C12)=CC=C2NC=C1C(=O)N(C1)C2CC1(C)CC(C)(C)C2 QNSCIZRHXLLGBB-UHFFFAOYSA-N 0.000 claims 1
• VBESUZJULNEXKH-UHFFFAOYSA-N [3-(4-butan-2-ylphenoxy)phenyl]-piperidin-1-ylmethanone Chemical compound C1=CC(C(C)CC)=CC=C1OC1=CC=CC(C(=O)N2CCCCC2)=C1 VBESUZJULNEXKH-UHFFFAOYSA-N 0.000 claims 1
• CJVRMJIOBJQEAV-UHFFFAOYSA-N [3-(4-methylphenyl)-1-adamantyl]-morpholin-4-ylmethanone Chemical compound C1=CC(C)=CC=C1C1(C2)CC(C3)(C(=O)N4CCOCC4)CC2CC3C1 CJVRMJIOBJQEAV-UHFFFAOYSA-N 0.000 claims 1
• XEPSNXSLHKEBRM-UHFFFAOYSA-N [3-(4-nitrophenyl)-1-adamantyl]-piperidin-1-ylmethanone Chemical compound C1=CC([N+](=O)[O-])=CC=C1C1(C2)CC(C3)(C(=O)N4CCCCC4)CC2CC3C1 XEPSNXSLHKEBRM-UHFFFAOYSA-N 0.000 claims 1
• BJRVESJGRXUAOZ-UHFFFAOYSA-N [3-(4-pyrazin-2-ylpiperazine-1-carbonyl)-1H-indol-5-yl]-(3,3,5-trimethyl-7-azabicyclo[3.2.1]octan-7-yl)methanone Chemical compound C1C(C)(C)CC(C)(C2)CC1N2C(=O)C(C=C12)=CC=C1NC=C2C(=O)N(CC1)CCN1C1=CN=CC=N1 BJRVESJGRXUAOZ-UHFFFAOYSA-N 0.000 claims 1
• WQSJQJSFTIXKBS-UHFFFAOYSA-N [3-(piperidine-1-carbonyl)-1H-indol-5-yl]-(3,3,5-trimethyl-7-azabicyclo[3.2.1]octan-7-yl)methanone Chemical compound C1C(C)(C)CC(C)(C2)CC1N2C(=O)C(C=C12)=CC=C1NC=C2C(=O)N1CCCCC1 WQSJQJSFTIXKBS-UHFFFAOYSA-N 0.000 claims 1
• XBVAARHOCNXTDS-UHFFFAOYSA-N [3-[(2,5-dichlorophenoxy)methyl]phenyl]-pyrrolidin-1-ylmethanone Chemical compound ClC1=CC=C(Cl)C(OCC=2C=C(C=CC=2)C(=O)N2CCCC2)=C1 XBVAARHOCNXTDS-UHFFFAOYSA-N 0.000 claims 1
• JTAJMIZQWOCLTK-UHFFFAOYSA-N [3-[(4-bromopyrazol-1-yl)methyl]phenyl]-(4-methylpiperidin-1-yl)methanone Chemical compound C1CC(C)CCN1C(=O)C1=CC=CC(CN2N=CC(Br)=C2)=C1 JTAJMIZQWOCLTK-UHFFFAOYSA-N 0.000 claims 1
• OMCIBMUMTYSSPK-UHFFFAOYSA-N [3-[(dimethylamino)methyl]-1H-indol-6-yl]-(3,3,5-trimethyl-7-azabicyclo[3.2.1]octan-7-yl)methanone Chemical compound C1C(CC(C)(C)C2)(C)CC2N1C(=O)C1=CC=C2C(CN(C)C)=CNC2=C1 OMCIBMUMTYSSPK-UHFFFAOYSA-N 0.000 claims 1
• KNBAAWYIPOJESR-UHFFFAOYSA-N [3-[2-(methoxymethyl)pyrrolidine-1-carbonyl]-1H-indol-5-yl]-(3,3,5-trimethyl-7-azabicyclo[3.2.1]octan-7-yl)methanone Chemical compound COCC1CCCN1C(=O)C1=CNC2=CC=C(C(=O)N3C4CC(CC(C)(C)C4)(C)C3)C=C12 KNBAAWYIPOJESR-UHFFFAOYSA-N 0.000 claims 1
• WRRDSTZWEUXENT-UHFFFAOYSA-N [3-[4-[(4-hydroxyphenyl)methyl]piperazine-1-carbonyl]-5-methoxyphenyl]-pyridin-2-ylmethanone Chemical compound C=1C(OC)=CC(C(=O)N2CCN(CC=3C=CC(O)=CC=3)CC2)=CC=1C(=O)C1=CC=CC=N1 WRRDSTZWEUXENT-UHFFFAOYSA-N 0.000 claims 1
• RBMIAGCMMUKOLZ-UHFFFAOYSA-N [3-bromo-5-(4-bromophenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]-(4-methylpiperazin-1-yl)methanone Chemical compound C1CN(C)CCN1C(=O)C1=NN(C(=CC(=N2)C=3C=CC(Br)=CC=3)C(F)(F)F)C2=C1Br RBMIAGCMMUKOLZ-UHFFFAOYSA-N 0.000 claims 1
• OQZLLOYMTFOOGJ-UHFFFAOYSA-N [3-bromo-5-(4-bromophenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]-morpholin-4-ylmethanone Chemical compound N=1N2C(C(F)(F)F)=CC(C=3C=CC(Br)=CC=3)=NC2=C(Br)C=1C(=O)N1CCOCC1 OQZLLOYMTFOOGJ-UHFFFAOYSA-N 0.000 claims 1
• IKWDBOHVSWZDMX-UHFFFAOYSA-N [3-bromo-5-(4-bromothiophen-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]-piperidin-1-ylmethanone Chemical compound N=1N2C(C(F)(F)F)=CC(C=3SC=C(Br)C=3)=NC2=C(Br)C=1C(=O)N1CCCCC1 IKWDBOHVSWZDMX-UHFFFAOYSA-N 0.000 claims 1
• NNKCPOPJCLZLMA-UHFFFAOYSA-N [3-bromo-5-(4-methoxyphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]-morpholin-4-ylmethanone Chemical compound C1=CC(OC)=CC=C1C1=NC2=C(Br)C(C(=O)N3CCOCC3)=NN2C(C(F)(F)F)=C1 NNKCPOPJCLZLMA-UHFFFAOYSA-N 0.000 claims 1
• AHLLDRLBEUYTHZ-UHFFFAOYSA-N [3-bromo-5-(4-methoxyphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]-piperidin-1-ylmethanone Chemical compound C1=CC(OC)=CC=C1C1=NC2=C(Br)C(C(=O)N3CCCCC3)=NN2C(C(F)(F)F)=C1 AHLLDRLBEUYTHZ-UHFFFAOYSA-N 0.000 claims 1
• PIZRZBMYLDUBDP-UHFFFAOYSA-N [3-bromo-5-(furan-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]-(4-methylpiperazin-1-yl)methanone Chemical compound C1CN(C)CCN1C(=O)C1=NN(C(=CC(=N2)C=3OC=CC=3)C(F)(F)F)C2=C1Br PIZRZBMYLDUBDP-UHFFFAOYSA-N 0.000 claims 1
• LSQLQAOFLAPUIW-UHFFFAOYSA-N [3-bromo-5-phenyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]-morpholin-4-ylmethanone Chemical compound N=1N2C(C(F)(F)F)=CC(C=3C=CC=CC=3)=NC2=C(Br)C=1C(=O)N1CCOCC1 LSQLQAOFLAPUIW-UHFFFAOYSA-N 0.000 claims 1
• XDTQQYCXNJYNME-UHFFFAOYSA-N [3-bromo-5-phenyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]-piperidin-1-ylmethanone Chemical compound N=1N2C(C(F)(F)F)=CC(C=3C=CC=CC=3)=NC2=C(Br)C=1C(=O)N1CCCCC1 XDTQQYCXNJYNME-UHFFFAOYSA-N 0.000 claims 1
• YDVNMNSWBQCLNS-UHFFFAOYSA-N [3-bromo-5-thiophen-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]-(2,6-dimethylpiperidin-1-yl)methanone Chemical compound CC1CCCC(C)N1C(=O)C1=NN(C(=CC(=N2)C=3SC=CC=3)C(F)(F)F)C2=C1Br YDVNMNSWBQCLNS-UHFFFAOYSA-N 0.000 claims 1
• UGBBEXFASJPQKS-UHFFFAOYSA-N [3-bromo-5-thiophen-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]-(2-ethylpiperidin-1-yl)methanone Chemical compound CCC1CCCCN1C(=O)C1=NN(C(=CC(=N2)C=3SC=CC=3)C(F)(F)F)C2=C1Br UGBBEXFASJPQKS-UHFFFAOYSA-N 0.000 claims 1
• NDSCASPUZDGXFQ-UHFFFAOYSA-N [3-bromo-5-thiophen-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]-(3,4-dihydro-2H-quinolin-1-yl)methanone Chemical compound N=1C2=C(Br)C(C(=O)N3C4=CC=CC=C4CCC3)=NN2C(C(F)(F)F)=CC=1C1=CC=CS1 NDSCASPUZDGXFQ-UHFFFAOYSA-N 0.000 claims 1
• FWRGZSBQRLITGD-UHFFFAOYSA-N [3-bromo-5-thiophen-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]-(4-methylpiperazin-1-yl)methanone Chemical compound C1CN(C)CCN1C(=O)C1=NN(C(=CC(=N2)C=3SC=CC=3)C(F)(F)F)C2=C1Br FWRGZSBQRLITGD-UHFFFAOYSA-N 0.000 claims 1
• IPFLJVVIYNCABX-UHFFFAOYSA-N [3-bromo-5-thiophen-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]-morpholin-4-ylmethanone Chemical compound N=1N2C(C(F)(F)F)=CC(C=3SC=CC=3)=NC2=C(Br)C=1C(=O)N1CCOCC1 IPFLJVVIYNCABX-UHFFFAOYSA-N 0.000 claims 1
• BGRXKZYMLGJNLE-UHFFFAOYSA-N [3-chloro-5-(3,4-dimethoxyphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]-piperidin-1-ylmethanone Chemical compound C1=C(OC)C(OC)=CC=C1C1=NC2=C(Cl)C(C(=O)N3CCCCC3)=NN2C(C(F)(F)F)=C1 BGRXKZYMLGJNLE-UHFFFAOYSA-N 0.000 claims 1
• DIDLIXOQHCWASJ-UHFFFAOYSA-N [3-chloro-5-(3,4-dimethoxyphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]-pyrrolidin-1-ylmethanone Chemical compound C1=C(OC)C(OC)=CC=C1C1=NC2=C(Cl)C(C(=O)N3CCCC3)=NN2C(C(F)(F)F)=C1 DIDLIXOQHCWASJ-UHFFFAOYSA-N 0.000 claims 1
• DNEQQZJCEXXTEI-UHFFFAOYSA-N [3-chloro-5-(4-chlorophenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]-(4-methylpiperazin-1-yl)methanone Chemical compound C1CN(C)CCN1C(=O)C1=NN(C(=CC(=N2)C=3C=CC(Cl)=CC=3)C(F)(F)F)C2=C1Cl DNEQQZJCEXXTEI-UHFFFAOYSA-N 0.000 claims 1
• YOAOJZNJQKWNDC-UHFFFAOYSA-N [3-chloro-5-(4-chlorophenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]-morpholin-4-ylmethanone Chemical compound N=1N2C(C(F)(F)F)=CC(C=3C=CC(Cl)=CC=3)=NC2=C(Cl)C=1C(=O)N1CCOCC1 YOAOJZNJQKWNDC-UHFFFAOYSA-N 0.000 claims 1
• HYKHOZGAMSNBGG-UHFFFAOYSA-N [3-chloro-5-(4-fluorophenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]-(4-methylpiperazin-1-yl)methanone Chemical compound C1CN(C)CCN1C(=O)C1=NN(C(=CC(=N2)C=3C=CC(F)=CC=3)C(F)(F)F)C2=C1Cl HYKHOZGAMSNBGG-UHFFFAOYSA-N 0.000 claims 1
• LJTYWHGULRIVJR-UHFFFAOYSA-N [3-chloro-5-(4-methoxyphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]-(4-methylpiperidin-1-yl)methanone Chemical compound C1=CC(OC)=CC=C1C1=NC2=C(Cl)C(C(=O)N3CCC(C)CC3)=NN2C(C(F)(F)F)=C1 LJTYWHGULRIVJR-UHFFFAOYSA-N 0.000 claims 1
• MAMIZECQBPDPGX-UHFFFAOYSA-N [3-chloro-5-(4-methoxyphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]-piperidin-1-ylmethanone Chemical compound C1=CC(OC)=CC=C1C1=NC2=C(Cl)C(C(=O)N3CCCCC3)=NN2C(C(F)(F)F)=C1 MAMIZECQBPDPGX-UHFFFAOYSA-N 0.000 claims 1
• ZSELJZHLIWSBJE-UHFFFAOYSA-N [3-chloro-5-(4-methylphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]-(4-methylpiperazin-1-yl)methanone Chemical compound C1CN(C)CCN1C(=O)C1=NN(C(=CC(=N2)C=3C=CC(C)=CC=3)C(F)(F)F)C2=C1Cl ZSELJZHLIWSBJE-UHFFFAOYSA-N 0.000 claims 1
• ZQVSIXWJIFATKL-UHFFFAOYSA-N [3-chloro-5-(4-methylphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]-(4-phenylpiperazin-1-yl)methanone Chemical compound C1=CC(C)=CC=C1C1=NC2=C(Cl)C(C(=O)N3CCN(CC3)C=3C=CC=CC=3)=NN2C(C(F)(F)F)=C1 ZQVSIXWJIFATKL-UHFFFAOYSA-N 0.000 claims 1
• DUORWAFRXXGDPJ-UHFFFAOYSA-N [3-chloro-5-(4-methylphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]-morpholin-4-ylmethanone Chemical compound C1=CC(C)=CC=C1C1=NC2=C(Cl)C(C(=O)N3CCOCC3)=NN2C(C(F)(F)F)=C1 DUORWAFRXXGDPJ-UHFFFAOYSA-N 0.000 claims 1
• TZJPBGWAOSZFEJ-UHFFFAOYSA-N [3-chloro-5-(furan-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]-(4-phenylpiperazin-1-yl)methanone Chemical compound N=1N2C(C(F)(F)F)=CC(C=3OC=CC=3)=NC2=C(Cl)C=1C(=O)N(CC1)CCN1C1=CC=CC=C1 TZJPBGWAOSZFEJ-UHFFFAOYSA-N 0.000 claims 1
• WXCHKMHOIBEIMP-UHFFFAOYSA-N [3-chloro-5-phenyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]-morpholin-4-ylmethanone Chemical compound N=1N2C(C(F)(F)F)=CC(C=3C=CC=CC=3)=NC2=C(Cl)C=1C(=O)N1CCOCC1 WXCHKMHOIBEIMP-UHFFFAOYSA-N 0.000 claims 1
• KMKAHLCUJHUPPE-UHFFFAOYSA-N [3-chloro-5-phenyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]-piperidin-1-ylmethanone Chemical compound N=1N2C(C(F)(F)F)=CC(C=3C=CC=CC=3)=NC2=C(Cl)C=1C(=O)N1CCCCC1 KMKAHLCUJHUPPE-UHFFFAOYSA-N 0.000 claims 1
• ZHLDHBHZOUXCGH-UHFFFAOYSA-N [3-chloro-5-phenyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]-pyrrolidin-1-ylmethanone Chemical compound N=1N2C(C(F)(F)F)=CC(C=3C=CC=CC=3)=NC2=C(Cl)C=1C(=O)N1CCCC1 ZHLDHBHZOUXCGH-UHFFFAOYSA-N 0.000 claims 1
• JLJRZKJHRJTXHG-UHFFFAOYSA-N [3-chloro-5-thiophen-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]-(2-ethylpiperidin-1-yl)methanone Chemical compound CCC1CCCCN1C(=O)C1=NN(C(=CC(=N2)C=3SC=CC=3)C(F)(F)F)C2=C1Cl JLJRZKJHRJTXHG-UHFFFAOYSA-N 0.000 claims 1
• CHLRAUZNHLSBRI-UHFFFAOYSA-N [3-chloro-5-thiophen-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]-(2-methylpiperidin-1-yl)methanone Chemical compound CC1CCCCN1C(=O)C1=NN(C(=CC(=N2)C=3SC=CC=3)C(F)(F)F)C2=C1Cl CHLRAUZNHLSBRI-UHFFFAOYSA-N 0.000 claims 1
• OVXCGVDCULWUCI-UHFFFAOYSA-N [3-chloro-5-thiophen-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]-(3,4-dihydro-1H-isoquinolin-2-yl)methanone Chemical compound N=1C2=C(Cl)C(C(=O)N3CC4=CC=CC=C4CC3)=NN2C(C(F)(F)F)=CC=1C1=CC=CS1 OVXCGVDCULWUCI-UHFFFAOYSA-N 0.000 claims 1
• QRYXTVPQYXQPNU-UHFFFAOYSA-N [3-chloro-5-thiophen-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]-(3,4-dihydro-2H-quinolin-1-yl)methanone Chemical compound N=1C2=C(Cl)C(C(=O)N3C4=CC=CC=C4CCC3)=NN2C(C(F)(F)F)=CC=1C1=CC=CS1 QRYXTVPQYXQPNU-UHFFFAOYSA-N 0.000 claims 1
• IBUSJDQPKCWIEP-UHFFFAOYSA-N [3-chloro-5-thiophen-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]-(4-methylpiperazin-1-yl)methanone Chemical compound C1CN(C)CCN1C(=O)C1=NN(C(=CC(=N2)C=3SC=CC=3)C(F)(F)F)C2=C1Cl IBUSJDQPKCWIEP-UHFFFAOYSA-N 0.000 claims 1
• AUPFDHLAVYZHJL-UHFFFAOYSA-N [3-chloro-5-thiophen-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]-(4-phenylpiperazin-1-yl)methanone Chemical compound N=1N2C(C(F)(F)F)=CC(C=3SC=CC=3)=NC2=C(Cl)C=1C(=O)N(CC1)CCN1C1=CC=CC=C1 AUPFDHLAVYZHJL-UHFFFAOYSA-N 0.000 claims 1
• CUONJIDMEIRDDS-UHFFFAOYSA-N [3-chloro-5-thiophen-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]-morpholin-4-ylmethanone Chemical compound N=1N2C(C(F)(F)F)=CC(C=3SC=CC=3)=NC2=C(Cl)C=1C(=O)N1CCOCC1 CUONJIDMEIRDDS-UHFFFAOYSA-N 0.000 claims 1
• WUXPNULLVNWTND-UHFFFAOYSA-N [3-chloro-5-thiophen-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]-piperidin-1-ylmethanone Chemical compound N=1N2C(C(F)(F)F)=CC(C=3SC=CC=3)=NC2=C(Cl)C=1C(=O)N1CCCCC1 WUXPNULLVNWTND-UHFFFAOYSA-N 0.000 claims 1
• OMIBIOQTLXECFO-UHFFFAOYSA-N [4-(1,2,4-triazol-1-yl)phenyl]-(3,3,5-trimethyl-7-azabicyclo[3.2.1]octan-7-yl)methanone Chemical compound C1C(C)(C)CC(C)(C2)CC1N2C(=O)C(C=C1)=CC=C1N1C=NC=N1 OMIBIOQTLXECFO-UHFFFAOYSA-N 0.000 claims 1
• MLAOSPGUZDRVNW-UHFFFAOYSA-N [4-(1H-imidazol-5-yl)piperidin-1-yl]-(4-pentylphenyl)methanone Chemical compound C1=CC(CCCCC)=CC=C1C(=O)N1CCC(C=2N=CNC=2)CC1 MLAOSPGUZDRVNW-UHFFFAOYSA-N 0.000 claims 1
• ABFRJGNQGQJOAT-UHFFFAOYSA-N [4-(2,3-dimethylphenyl)piperazin-1-yl]-(2-methylphenyl)methanone Chemical compound CC1=CC=CC(N2CCN(CC2)C(=O)C=2C(=CC=CC=2)C)=C1C ABFRJGNQGQJOAT-UHFFFAOYSA-N 0.000 claims 1
• KTOGWFSKGNVKMK-UHFFFAOYSA-N [4-(2,3-dimethylphenyl)piperazin-1-yl]-(3-methoxyphenyl)methanone Chemical compound COC1=CC=CC(C(=O)N2CCN(CC2)C=2C(=C(C)C=CC=2)C)=C1 KTOGWFSKGNVKMK-UHFFFAOYSA-N 0.000 claims 1
• GITJXPAWMDCFHF-UHFFFAOYSA-N [4-(2,5-dimethylpyrrol-1-yl)phenyl]-(4-methylpiperidin-1-yl)methanone Chemical compound C1CC(C)CCN1C(=O)C1=CC=C(N2C(=CC=C2C)C)C=C1 GITJXPAWMDCFHF-UHFFFAOYSA-N 0.000 claims 1
• VGLSLVIKCNISMT-UHFFFAOYSA-N [4-(2-chloro-6-nitrophenoxy)phenyl]-piperidin-1-ylmethanone Chemical compound [O-][N+](=O)C1=CC=CC(Cl)=C1OC1=CC=C(C(=O)N2CCCCC2)C=C1 VGLSLVIKCNISMT-UHFFFAOYSA-N 0.000 claims 1
• RIHMZRJSBOXKJG-UHFFFAOYSA-N [4-(2-chloro-6-nitrophenyl)piperazin-1-yl]-(4-methoxyphenyl)methanone Chemical compound C1=CC(OC)=CC=C1C(=O)N1CCN(C=2C(=CC=CC=2Cl)[N+]([O-])=O)CC1 RIHMZRJSBOXKJG-UHFFFAOYSA-N 0.000 claims 1
• YSIGHMXTVPOKOG-UHFFFAOYSA-N [4-(2-chloro-6-nitrophenyl)piperazin-1-yl]-(4-methylphenyl)methanone Chemical compound C1=CC(C)=CC=C1C(=O)N1CCN(C=2C(=CC=CC=2Cl)[N+]([O-])=O)CC1 YSIGHMXTVPOKOG-UHFFFAOYSA-N 0.000 claims 1
• AJFXSFNLQXVRRM-UHFFFAOYSA-N [4-(2-chlorophenyl)piperazin-1-yl]-[5-thiophen-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]methanone Chemical compound N=1N2C(C(F)(F)F)=CC(C=3SC=CC=3)=NC2=CC=1C(=O)N(CC1)CCN1C1=CC=CC=C1Cl AJFXSFNLQXVRRM-UHFFFAOYSA-N 0.000 claims 1
• WTPUHJGRHJWNSZ-UHFFFAOYSA-N [4-(2-methoxyphenyl)piperazin-1-yl]-pyrazolo[1,5-a]pyrimidin-3-ylmethanone Chemical compound COC1=CC=CC=C1N1CCN(C(=O)C2=C3N=CC=CN3N=C2)CC1 WTPUHJGRHJWNSZ-UHFFFAOYSA-N 0.000 claims 1
• ZVJVFOPIJNWPMV-UHFFFAOYSA-N [4-(3,4-dihydro-2H-quinoline-1-carbonyl)phenyl] acetate Chemical compound C1=CC(OC(=O)C)=CC=C1C(=O)N1C2=CC=CC=C2CCC1 ZVJVFOPIJNWPMV-UHFFFAOYSA-N 0.000 claims 1
• LHZYREUROAQJCW-UHFFFAOYSA-N [4-(3,5-dimethylpiperidine-1-carbonyl)phenyl] acetate Chemical compound C1C(C)CC(C)CN1C(=O)C1=CC=C(OC(C)=O)C=C1 LHZYREUROAQJCW-UHFFFAOYSA-N 0.000 claims 1
• VRCVFJNYHABRSF-UHFFFAOYSA-N [4-(3,5-dimethylpyrazol-1-yl)phenyl]-(3,3,5-trimethyl-7-azabicyclo[3.2.1]octan-7-yl)methanone Chemical compound N1=C(C)C=C(C)N1C1=CC=C(C(=O)N2C3CC(CC(C)(C)C3)(C)C2)C=C1 VRCVFJNYHABRSF-UHFFFAOYSA-N 0.000 claims 1
• VFHMMKKEAMZKKJ-UHFFFAOYSA-N [4-(3,5-dinitrophenoxy)phenyl]-(2-ethylpiperidin-1-yl)methanone Chemical compound CCC1CCCCN1C(=O)C(C=C1)=CC=C1OC1=CC([N+]([O-])=O)=CC([N+]([O-])=O)=C1 VFHMMKKEAMZKKJ-UHFFFAOYSA-N 0.000 claims 1
• QTJKRZCTNZGLKQ-UHFFFAOYSA-N [4-(3-chlorophenyl)piperazin-1-yl]-[5-(4-methylphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-3-yl]methanone Chemical compound C1=CC(C)=CC=C1C1=NC2=C(C(=O)N3CCN(CC3)C=3C=C(Cl)C=CC=3)C=NN2C(C(F)(F)F)=C1 QTJKRZCTNZGLKQ-UHFFFAOYSA-N 0.000 claims 1
• PRVPUYZTKITVQM-UHFFFAOYSA-N [4-(4-benzylpiperidine-1-carbonyl)phenyl] acetate Chemical compound C1=CC(OC(=O)C)=CC=C1C(=O)N1CCC(CC=2C=CC=CC=2)CC1 PRVPUYZTKITVQM-UHFFFAOYSA-N 0.000 claims 1
• SZQAZKPTPIQYQP-UHFFFAOYSA-N [4-(4-bromophenyl)sulfonylpiperazin-1-yl]-(furan-2-yl)methanone Chemical compound C1=CC(Br)=CC=C1S(=O)(=O)N1CCN(C(=O)C=2OC=CC=2)CC1 SZQAZKPTPIQYQP-UHFFFAOYSA-N 0.000 claims 1
• HHTURCPSBLTVNU-UHFFFAOYSA-N [4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-(1H-indol-5-yl)methanone Chemical compound C1CN(C(=O)C=2C=C3C=CNC3=CC=2)CCC1(O)C1=CC=C(Cl)C=C1 HHTURCPSBLTVNU-UHFFFAOYSA-N 0.000 claims 1
• LLHWIRXTBXXNRU-UHFFFAOYSA-N [4-(4-chlorophenyl)piperazin-1-yl]-[7-(difluoromethyl)-5-(4-methoxyphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]methanone Chemical compound C1=CC(OC)=CC=C1C1=NC2=C(C(=O)N3CCN(CC3)C=3C=CC(Cl)=CC=3)C=NN2C(C(F)F)=C1 LLHWIRXTBXXNRU-UHFFFAOYSA-N 0.000 claims 1
• ASFLTSMNCCHSLI-UHFFFAOYSA-N [4-(4-fluorophenyl)piperazin-1-yl]-(7-methyl-5-phenylpyrazolo[1,5-a]pyrimidin-2-yl)methanone Chemical compound N=1N2C(C)=CC(C=3C=CC=CC=3)=NC2=CC=1C(=O)N(CC1)CCN1C1=CC=C(F)C=C1 ASFLTSMNCCHSLI-UHFFFAOYSA-N 0.000 claims 1
• SGWPHKIIOYEJPE-UHFFFAOYSA-N [4-(4-fluorophenyl)piperazin-1-yl]-[5-(3-methoxyphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-3-yl]methanone Chemical compound COC1=CC=CC(C2=NC3=C(C(=O)N4CCN(CC4)C=4C=CC(F)=CC=4)C=NN3C(=C2)C(F)(F)F)=C1 SGWPHKIIOYEJPE-UHFFFAOYSA-N 0.000 claims 1
• TXVZYSSZZWZFBX-UHFFFAOYSA-N [4-(4-fluorophenyl)piperazin-1-yl]-[5-(4-methylphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]methanone Chemical compound C1=CC(C)=CC=C1C1=NC2=CC(C(=O)N3CCN(CC3)C=3C=CC(F)=CC=3)=NN2C(C(F)(F)F)=C1 TXVZYSSZZWZFBX-UHFFFAOYSA-N 0.000 claims 1
• ORFIXQALCZPHRA-UHFFFAOYSA-N [4-(4-fluorophenyl)piperazin-1-yl]-[5-(furan-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]methanone Chemical compound C1=CC(F)=CC=C1N1CCN(C(=O)C2=NN3C(=CC(=NC3=C2)C=2OC=CC=2)C(F)(F)F)CC1 ORFIXQALCZPHRA-UHFFFAOYSA-N 0.000 claims 1
• IFQXIUBJEQMLBU-UHFFFAOYSA-N [4-(4-fluorophenyl)piperazin-1-yl]-[5-phenyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]methanone Chemical compound C1=CC(F)=CC=C1N1CCN(C(=O)C2=NN3C(=CC(=NC3=C2)C=2C=CC=CC=2)C(F)(F)F)CC1 IFQXIUBJEQMLBU-UHFFFAOYSA-N 0.000 claims 1
• GOHLNKFRUYWBQB-UHFFFAOYSA-N [4-(4-fluorophenyl)piperazin-1-yl]-[5-thiophen-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-3-yl]methanone Chemical compound C1=CC(F)=CC=C1N1CCN(C(=O)C2=C3N=C(C=C(N3N=C2)C(F)(F)F)C=2SC=CC=2)CC1 GOHLNKFRUYWBQB-UHFFFAOYSA-N 0.000 claims 1
• JTHNOLKHHKCTPL-UHFFFAOYSA-N [4-(4-methylpiperidine-1-carbonyl)phenyl] acetate Chemical compound C1CC(C)CCN1C(=O)C1=CC=C(OC(C)=O)C=C1 JTHNOLKHHKCTPL-UHFFFAOYSA-N 0.000 claims 1
• DRTKTDQTTOPSAQ-UHFFFAOYSA-N [4-(adamantane-1-carbonylamino)-2,6-dimethylpyridin-3-yl] adamantane-1-carboxylate Chemical compound C1C(C2)CC(C3)CC2CC13C(=O)OC1=C(NC(=O)C23CC4CC(CC(C4)C2)C3)C=C(C)N=C1C DRTKTDQTTOPSAQ-UHFFFAOYSA-N 0.000 claims 1
• ITMCBJAQMJMNNC-UHFFFAOYSA-N [4-(adamantane-1-carbonylamino)-2-ethyl-6-methylpyridin-3-yl] adamantane-1-carboxylate Chemical compound C1C(C2)CC(C3)CC2CC13C(=O)OC1=C(NC(=O)C23CC4CC(CC(C4)C2)C3)C=C(C)N=C1CC ITMCBJAQMJMNNC-UHFFFAOYSA-N 0.000 claims 1
• WGAADDNVYHZGNK-UHFFFAOYSA-N [4-(azepane-1-carbonyl)phenyl] acetate Chemical compound C1=CC(OC(=O)C)=CC=C1C(=O)N1CCCCCC1 WGAADDNVYHZGNK-UHFFFAOYSA-N 0.000 claims 1
• XQKXJVMZSDQGOF-UHFFFAOYSA-N [4-(benzenesulfonyl)phenyl]-(3,3,5-trimethyl-7-azabicyclo[3.2.1]octan-7-yl)methanone Chemical compound C1C(C)(C)CC(C)(C2)CC1N2C(=O)C(C=C1)=CC=C1S(=O)(=O)C1=CC=CC=C1 XQKXJVMZSDQGOF-UHFFFAOYSA-N 0.000 claims 1
• DGWFQDMNODCWRA-UHFFFAOYSA-N [4-(dimethylamino)phenyl]-(3,3,5-trimethyl-7-azabicyclo[3.2.1]octan-7-yl)methanone Chemical compound C1=CC(N(C)C)=CC=C1C(=O)N1C(CC(C)(C)C2)CC2(C)C1 DGWFQDMNODCWRA-UHFFFAOYSA-N 0.000 claims 1
• CQOAUJONINNUQL-UHFFFAOYSA-N [4-(dimethylamino)phenyl]-(3-hydroxy-3-methyl-8-azabicyclo[3.2.1]octan-8-yl)methanone Chemical compound C1=CC(N(C)C)=CC=C1C(=O)N1C2CCC1CC(C)(O)C2 CQOAUJONINNUQL-UHFFFAOYSA-N 0.000 claims 1
• HNFLFHXMJRABSF-UHFFFAOYSA-N [4-(dimethylamino)phenyl]-(3-hydroxy-8-azabicyclo[3.2.1]octan-8-yl)methanone Chemical compound C1=CC(N(C)C)=CC=C1C(=O)N1C2CCC1CC(O)C2 HNFLFHXMJRABSF-UHFFFAOYSA-N 0.000 claims 1
• BFXZQIBGNIOOGD-UHFFFAOYSA-N [4-(tetrazol-1-yl)phenyl]-(3,3,5-trimethyl-7-azabicyclo[3.2.1]octan-7-yl)methanone Chemical compound C1C(C)(C)CC(C)(C2)CC1N2C(=O)C(C=C1)=CC=C1N1C=NN=N1 BFXZQIBGNIOOGD-UHFFFAOYSA-N 0.000 claims 1
• BNQBIMPSYNRLDO-UHFFFAOYSA-N [4-[(2-methoxynaphthalen-1-yl)methyl]piperazin-1-yl]-(4-methoxyphenyl)methanone Chemical compound C1=CC(OC)=CC=C1C(=O)N1CCN(CC=2C3=CC=CC=C3C=CC=2OC)CC1 BNQBIMPSYNRLDO-UHFFFAOYSA-N 0.000 claims 1
• QOMHEACWNDKGIP-UHFFFAOYSA-N [4-[(2-nitrophenyl)methyl]piperidin-1-yl]-phenylmethanone Chemical compound [O-][N+](=O)C1=CC=CC=C1CC1CCN(C(=O)C=2C=CC=CC=2)CC1 QOMHEACWNDKGIP-UHFFFAOYSA-N 0.000 claims 1
• NHNVDTFKTKGEEU-UHFFFAOYSA-N [4-[(4-chlorophenyl)sulfanylmethyl]phenyl]-morpholin-4-ylmethanone Chemical compound C1=CC(Cl)=CC=C1SCC1=CC=C(C(=O)N2CCOCC2)C=C1 NHNVDTFKTKGEEU-UHFFFAOYSA-N 0.000 claims 1
• GUFOXFGOAZJHND-UHFFFAOYSA-N [4-[(4-chlorophenyl)sulfanylmethyl]phenyl]-pyrrolidin-1-ylmethanone Chemical compound C1=CC(Cl)=CC=C1SCC1=CC=C(C(=O)N2CCCC2)C=C1 GUFOXFGOAZJHND-UHFFFAOYSA-N 0.000 claims 1
• YXSKXLLBOGENMA-UHFFFAOYSA-N [4-[(4-ethoxyphenoxy)methyl]phenyl]-(4-methylpiperidin-1-yl)methanone Chemical compound C1=CC(OCC)=CC=C1OCC1=CC=C(C(=O)N2CCC(C)CC2)C=C1 YXSKXLLBOGENMA-UHFFFAOYSA-N 0.000 claims 1
• JXGWQAJHERXXHX-UHFFFAOYSA-N [4-[(4-nitrophenyl)methyl]piperidin-1-yl]-phenylmethanone Chemical compound C1=CC([N+](=O)[O-])=CC=C1CC1CCN(C(=O)C=2C=CC=CC=2)CC1 JXGWQAJHERXXHX-UHFFFAOYSA-N 0.000 claims 1
• QFPAZJNBQHCFBM-UHFFFAOYSA-N [4-[3-(trifluoromethyl)pyrazol-1-yl]phenyl]-(3,3,5-trimethyl-7-azabicyclo[3.2.1]octan-7-yl)methanone Chemical compound C1C(C)(C)CC(C)(C2)CC1N2C(=O)C(C=C1)=CC=C1N1C=CC(C(F)(F)F)=N1 QFPAZJNBQHCFBM-UHFFFAOYSA-N 0.000 claims 1
• CUMNVZZYZWYMCG-UHFFFAOYSA-N [4-[3-bromo-5-(furan-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carbonyl]piperazin-1-yl]-phenylmethanone Chemical compound N=1N2C(C(F)(F)F)=CC(C=3OC=CC=3)=NC2=C(Br)C=1C(=O)N(CC1)CCN1C(=O)C1=CC=CC=C1 CUMNVZZYZWYMCG-UHFFFAOYSA-N 0.000 claims 1
• XLKHWLQFNIVDQD-UHFFFAOYSA-N [4-[3-chloro-5-(4-chlorophenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carbonyl]piperazin-1-yl]-phenylmethanone Chemical compound N=1N2C(C(F)(F)F)=CC(C=3C=CC(Cl)=CC=3)=NC2=C(Cl)C=1C(=O)N(CC1)CCN1C(=O)C1=CC=CC=C1 XLKHWLQFNIVDQD-UHFFFAOYSA-N 0.000 claims 1
• JMKAVCRGYSRJOJ-UHFFFAOYSA-N [4-[5-(4-bromophenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carbonyl]piperazin-1-yl]-phenylmethanone Chemical compound N=1N2C(C(F)(F)F)=CC(C=3C=CC(Br)=CC=3)=NC2=CC=1C(=O)N(CC1)CCN1C(=O)C1=CC=CC=C1 JMKAVCRGYSRJOJ-UHFFFAOYSA-N 0.000 claims 1
• GDWYKYYJFQOMCO-UHFFFAOYSA-N [4-[7-(difluoromethyl)-5-(4-methoxyphenyl)pyrazolo[1,5-a]pyrimidine-3-carbonyl]piperazin-1-yl]-(furan-2-yl)methanone Chemical compound C1=CC(OC)=CC=C1C1=NC2=C(C(=O)N3CCN(CC3)C(=O)C=3OC=CC=3)C=NN2C(C(F)F)=C1 GDWYKYYJFQOMCO-UHFFFAOYSA-N 0.000 claims 1
• CJLUNEBNAGOIAL-UHFFFAOYSA-N [4-[7-(difluoromethyl)-5-phenylpyrazolo[1,5-a]pyrimidine-3-carbonyl]piperazin-1-yl]-(2-methylpyrazol-3-yl)methanone Chemical compound CN1N=CC=C1C(=O)N1CCN(C(=O)C2=C3N=C(C=C(N3N=C2)C(F)F)C=2C=CC=CC=2)CC1 CJLUNEBNAGOIAL-UHFFFAOYSA-N 0.000 claims 1
• OSYQBPIFCOPZNK-UHFFFAOYSA-N [4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl]-(3,3,5-trimethyl-7-azabicyclo[3.2.1]octan-7-yl)methanone Chemical compound S1C(C(=O)N2C3CC(CC(C)(C)C3)(C)C2)=C(C)N=C1C1=CC=C(C(F)(F)F)C=C1 OSYQBPIFCOPZNK-UHFFFAOYSA-N 0.000 claims 1
• CHKYSZUKDIJJKQ-UHFFFAOYSA-N [5-(1,3-benzodioxol-5-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]-(4-benzylpiperazin-1-yl)methanone Chemical compound N=1N2C(C(F)(F)F)=CC(C=3C=C4OCOC4=CC=3)=NC2=CC=1C(=O)N(CC1)CCN1CC1=CC=CC=C1 CHKYSZUKDIJJKQ-UHFFFAOYSA-N 0.000 claims 1
• UBIDLTHYPKQOQS-UHFFFAOYSA-N [5-(1,3-benzodioxol-5-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]-(4-methylpiperazin-1-yl)methanone Chemical compound C1CN(C)CCN1C(=O)C1=NN2C(C(F)(F)F)=CC(C=3C=C4OCOC4=CC=3)=NC2=C1 UBIDLTHYPKQOQS-UHFFFAOYSA-N 0.000 claims 1
• YXRYCIBRJNETRE-UHFFFAOYSA-N [5-(1,3-benzodioxol-5-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]-(6,7-dimethoxy-1-methyl-3,4-dihydro-1H-isoquinolin-2-yl)methanone Chemical compound C1=C2OCOC2=CC(C2=NC3=CC(=NN3C(=C2)C(F)(F)F)C(=O)N2CCC=3C=C(C(=CC=3C2C)OC)OC)=C1 YXRYCIBRJNETRE-UHFFFAOYSA-N 0.000 claims 1
• IXDKAUWCEOZLPM-UHFFFAOYSA-N [5-(1,3-benzodioxol-5-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]-morpholin-4-ylmethanone Chemical compound N=1N2C(C(F)(F)F)=CC(C=3C=C4OCOC4=CC=3)=NC2=CC=1C(=O)N1CCOCC1 IXDKAUWCEOZLPM-UHFFFAOYSA-N 0.000 claims 1
• LCWGYHMKPRJELO-UHFFFAOYSA-N [5-(1,3-benzodioxol-5-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]-piperidin-1-ylmethanone Chemical compound N=1N2C(C(F)(F)F)=CC(C=3C=C4OCOC4=CC=3)=NC2=CC=1C(=O)N1CCCCC1 LCWGYHMKPRJELO-UHFFFAOYSA-N 0.000 claims 1
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• PRGUGWPVKZIZPE-UHFFFAOYSA-N [7-(difluoromethyl)-5-(4-methoxyphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]-morpholin-4-ylmethanone Chemical compound C1=CC(OC)=CC=C1C1=NC2=C(C(=O)N3CCOCC3)C=NN2C(C(F)F)=C1 PRGUGWPVKZIZPE-UHFFFAOYSA-N 0.000 claims 1
• GQQBBYVKFRESMU-UHFFFAOYSA-N [7-(difluoromethyl)-5-(4-methoxyphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]-thiomorpholin-4-ylmethanone Chemical compound C1=CC(OC)=CC=C1C1=NC2=C(C(=O)N3CCSCC3)C=NN2C(C(F)F)=C1 GQQBBYVKFRESMU-UHFFFAOYSA-N 0.000 claims 1
• RQRBUSCZUJCZIA-UHFFFAOYSA-N [7-(difluoromethyl)-5-(4-methylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]-(3-methylpiperidin-1-yl)methanone Chemical compound C1C(C)CCCN1C(=O)C1=C2N=C(C=3C=CC(C)=CC=3)C=C(C(F)F)N2N=C1 RQRBUSCZUJCZIA-UHFFFAOYSA-N 0.000 claims 1
• ABRBJPZAPLWUTA-UHFFFAOYSA-N [7-(difluoromethyl)-5-(4-methylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]-(4-ethylpiperazin-1-yl)methanone Chemical compound C1CN(CC)CCN1C(=O)C1=C2N=C(C=3C=CC(C)=CC=3)C=C(C(F)F)N2N=C1 ABRBJPZAPLWUTA-UHFFFAOYSA-N 0.000 claims 1
• IJWXSKWIASJQNF-UHFFFAOYSA-N [7-(difluoromethyl)-5-(4-methylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]-(4-pyridin-2-ylpiperazin-1-yl)methanone Chemical compound C1=CC(C)=CC=C1C1=NC2=C(C(=O)N3CCN(CC3)C=3N=CC=CC=3)C=NN2C(C(F)F)=C1 IJWXSKWIASJQNF-UHFFFAOYSA-N 0.000 claims 1
• BLABIJIFXATKBP-UHFFFAOYSA-N [7-(difluoromethyl)-5-(4-methylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]-morpholin-4-ylmethanone Chemical compound C1=CC(C)=CC=C1C1=NC2=C(C(=O)N3CCOCC3)C=NN2C(C(F)F)=C1 BLABIJIFXATKBP-UHFFFAOYSA-N 0.000 claims 1
• AAHGCCGJWBYLKR-UHFFFAOYSA-N [7-(difluoromethyl)-5-methylpyrazolo[1,5-a]pyrimidin-3-yl]-piperidin-1-ylmethanone Chemical compound C=12N=C(C)C=C(C(F)F)N2N=CC=1C(=O)N1CCCCC1 AAHGCCGJWBYLKR-UHFFFAOYSA-N 0.000 claims 1
• ISTMZTNEGHDWRR-UHFFFAOYSA-N [7-(difluoromethyl)-5-phenylpyrazolo[1,5-a]pyrimidin-3-yl]-(2-ethylimidazol-1-yl)methanone Chemical compound CCC1=NC=CN1C(=O)C1=C2N=C(C=3C=CC=CC=3)C=C(C(F)F)N2N=C1 ISTMZTNEGHDWRR-UHFFFAOYSA-N 0.000 claims 1
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• SQXUMPJPLQHUGH-UHFFFAOYSA-N [7-(difluoromethyl)-5-phenylpyrazolo[1,5-a]pyrimidin-3-yl]-thiomorpholin-4-ylmethanone Chemical compound C1=NN2C(C(F)F)=CC(C=3C=CC=CC=3)=NC2=C1C(=O)N1CCSCC1 SQXUMPJPLQHUGH-UHFFFAOYSA-N 0.000 claims 1
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• 125000005325 aryloxy aryl group Chemical group 0.000 claims 1
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• SAAZNLRJHODSLQ-UHFFFAOYSA-N azepan-1-yl-[3-bromo-5-(4-bromophenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]methanone Chemical compound N=1N2C(C(F)(F)F)=CC(C=3C=CC(Br)=CC=3)=NC2=C(Br)C=1C(=O)N1CCCCCC1 SAAZNLRJHODSLQ-UHFFFAOYSA-N 0.000 claims 1
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• QUDHGQRQAPWFLO-UHFFFAOYSA-N azepan-1-yl-[3-chloro-5-(4-chlorophenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]methanone Chemical compound N=1N2C(C(F)(F)F)=CC(C=3C=CC(Cl)=CC=3)=NC2=C(Cl)C=1C(=O)N1CCCCCC1 QUDHGQRQAPWFLO-UHFFFAOYSA-N 0.000 claims 1
• PQOHXHNCHGUWNG-UHFFFAOYSA-N azepan-1-yl-[3-chloro-5-(4-methylphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]methanone Chemical compound C1=CC(C)=CC=C1C1=NC2=C(Cl)C(C(=O)N3CCCCCC3)=NN2C(C(F)(F)F)=C1 PQOHXHNCHGUWNG-UHFFFAOYSA-N 0.000 claims 1
• OWCCNJVYQXMRFZ-UHFFFAOYSA-N azepan-1-yl-[3-chloro-5-phenyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]methanone Chemical compound N=1N2C(C(F)(F)F)=CC(C=3C=CC=CC=3)=NC2=C(Cl)C=1C(=O)N1CCCCCC1 OWCCNJVYQXMRFZ-UHFFFAOYSA-N 0.000 claims 1
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• UCPQJIKFXBCUQB-UHFFFAOYSA-N azepan-1-yl-[4-[(4-chlorophenyl)sulfanylmethyl]phenyl]methanone Chemical compound C1=CC(Cl)=CC=C1SCC1=CC=C(C(=O)N2CCCCCC2)C=C1 UCPQJIKFXBCUQB-UHFFFAOYSA-N 0.000 claims 1
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• FBPKITYGTZFHKY-UHFFFAOYSA-N azepan-1-yl-[5-(1,3-benzodioxol-5-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-3-yl]methanone Chemical compound C1=NN2C(C(F)(F)F)=CC(C=3C=C4OCOC4=CC=3)=NC2=C1C(=O)N1CCCCCC1 FBPKITYGTZFHKY-UHFFFAOYSA-N 0.000 claims 1
• SOENLCFYVWXZOE-UHFFFAOYSA-N azepan-1-yl-[5-(3,4-dichlorophenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]methanone Chemical compound N=1N2C(C(F)(F)F)=CC(C=3C=C(Cl)C(Cl)=CC=3)=NC2=CC=1C(=O)N1CCCCCC1 SOENLCFYVWXZOE-UHFFFAOYSA-N 0.000 claims 1
• QRJRQZMDTJHECQ-UHFFFAOYSA-N azepan-1-yl-[5-(3,4-dimethoxyphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]methanone Chemical compound C1=C(OC)C(OC)=CC=C1C1=NC2=CC(C(=O)N3CCCCCC3)=NN2C(C(F)(F)F)=C1 QRJRQZMDTJHECQ-UHFFFAOYSA-N 0.000 claims 1
• BCRNBXQKTYGNRY-UHFFFAOYSA-N azepan-1-yl-[5-(4-bromophenyl)-3-chloro-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]methanone Chemical compound N=1N2C(C(F)(F)F)=CC(C=3C=CC(Br)=CC=3)=NC2=C(Cl)C=1C(=O)N1CCCCCC1 BCRNBXQKTYGNRY-UHFFFAOYSA-N 0.000 claims 1
• FHZLMVBPLCIKJI-UHFFFAOYSA-N azepan-1-yl-[5-(4-bromophenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]methanone Chemical compound N=1N2C(C(F)(F)F)=CC(C=3C=CC(Br)=CC=3)=NC2=CC=1C(=O)N1CCCCCC1 FHZLMVBPLCIKJI-UHFFFAOYSA-N 0.000 claims 1
• JTBLLIOAQLCDTO-UHFFFAOYSA-N azepan-1-yl-[5-(4-bromophenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-3-yl]methanone Chemical compound C1=NN2C(C(F)(F)F)=CC(C=3C=CC(Br)=CC=3)=NC2=C1C(=O)N1CCCCCC1 JTBLLIOAQLCDTO-UHFFFAOYSA-N 0.000 claims 1
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• ZPRMVXIWDAGRNB-UHFFFAOYSA-N azepan-1-yl-[5-(4-fluorophenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]methanone Chemical compound C1=CC(F)=CC=C1C1=NC2=CC(C(=O)N3CCCCCC3)=NN2C(C(F)(F)F)=C1 ZPRMVXIWDAGRNB-UHFFFAOYSA-N 0.000 claims 1
• WIPKOJFJCNOQLA-UHFFFAOYSA-N azepan-1-yl-[5-(4-nitrophenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]methanone Chemical compound C1=CC([N+](=O)[O-])=CC=C1C1=NC2=CC(C(=O)N3CCCCCC3)=NN2C(C(F)(F)F)=C1 WIPKOJFJCNOQLA-UHFFFAOYSA-N 0.000 claims 1
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• IJINABFBHKFXNV-UHFFFAOYSA-N azepan-1-yl-[5-[(2-nitrophenoxy)methyl]furan-2-yl]methanone Chemical compound [O-][N+](=O)C1=CC=CC=C1OCC1=CC=C(C(=O)N2CCCCCC2)O1 IJINABFBHKFXNV-UHFFFAOYSA-N 0.000 claims 1
• ZHJBYQGKWYMMGA-UHFFFAOYSA-N azepan-1-yl-[5-[(4-chloro-3,5-dimethylpyrazol-1-yl)methyl]furan-2-yl]methanone Chemical compound CC1=C(Cl)C(C)=NN1CC1=CC=C(C(=O)N2CCCCCC2)O1 ZHJBYQGKWYMMGA-UHFFFAOYSA-N 0.000 claims 1
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• ILBDOFYZWPFZAY-UHFFFAOYSA-N azepan-1-yl-[5-cyclopropyl-7-(difluoromethyl)pyrazolo[1,5-a]pyrimidin-3-yl]methanone Chemical compound C1=NN2C(C(F)F)=CC(C3CC3)=NC2=C1C(=O)N1CCCCCC1 ILBDOFYZWPFZAY-UHFFFAOYSA-N 0.000 claims 1
• KPUHGPXZPOFCLH-UHFFFAOYSA-N azepan-1-yl-[5-thiophen-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-3-yl]methanone Chemical compound C1=NN2C(C(F)(F)F)=CC(C=3SC=CC=3)=NC2=C1C(=O)N1CCCCCC1 KPUHGPXZPOFCLH-UHFFFAOYSA-N 0.000 claims 1
• WHFSDGUBUCEVTA-UHFFFAOYSA-N azepan-1-yl-[7-(difluoromethyl)-5-phenylpyrazolo[1,5-a]pyrimidin-3-yl]methanone Chemical compound C1=NN2C(C(F)F)=CC(C=3C=CC=CC=3)=NC2=C1C(=O)N1CCCCCC1 WHFSDGUBUCEVTA-UHFFFAOYSA-N 0.000 claims 1
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• VIZHYOQUNVSIAV-UHFFFAOYSA-N butyl 2-(N-benzoyl-3-chloro-4-fluoroanilino)propanoate Chemical compound C=1C=C(F)C(Cl)=CC=1N(C(C)C(=O)OCCCC)C(=O)C1=CC=CC=C1 VIZHYOQUNVSIAV-UHFFFAOYSA-N 0.000 claims 1
• 239000011203 carbon fibre reinforced carbon Substances 0.000 claims 1
• 125000005243 carbonyl alkyl group Chemical group 0.000 claims 1
• 238000006243 chemical reaction Methods 0.000 claims 1
• 238000002648 combination therapy Methods 0.000 claims 1
• 125000001316 cycloalkyl alkyl group Chemical group 0.000 claims 1
• DOHBALJMFBMLDS-UHFFFAOYSA-N cyclohexyl 2-[(4-benzyl-5-pyridin-3-yl-1,2,4-triazol-3-yl)sulfanyl]acetate Chemical compound C1CCCCC1OC(=O)CSC(N1CC=2C=CC=CC=2)=NN=C1C1=CC=CN=C1 DOHBALJMFBMLDS-UHFFFAOYSA-N 0.000 claims 1
• GDYPXATYYNJLNJ-UHFFFAOYSA-N cyclohexyl 2-[(5-benzyl-4-methyl-1,2,4-triazol-3-yl)sulfanyl]acetate Chemical compound N=1N=C(SCC(=O)OC2CCCCC2)N(C)C=1CC1=CC=CC=C1 GDYPXATYYNJLNJ-UHFFFAOYSA-N 0.000 claims 1
• OEEDQEZCWMYAJS-UHFFFAOYSA-N cyclohexyl 2-[[4-ethyl-5-[(4-fluoroanilino)methyl]-1,2,4-triazol-3-yl]sulfanyl]acetate Chemical compound N=1N=C(SCC(=O)OC2CCCCC2)N(CC)C=1CNC1=CC=C(F)C=C1 OEEDQEZCWMYAJS-UHFFFAOYSA-N 0.000 claims 1
• MUAQWJFXTAODNQ-UHFFFAOYSA-N cyclohexyl 2-[[5-(4-bromophenyl)-4-methyl-1,2,4-triazol-3-yl]sulfanyl]acetate Chemical compound N=1N=C(C=2C=CC(Br)=CC=2)N(C)C=1SCC(=O)OC1CCCCC1 MUAQWJFXTAODNQ-UHFFFAOYSA-N 0.000 claims 1
• QKPVMEAYJPEUBD-UHFFFAOYSA-N cyclohexyl 2-[[5-[(2,4-dimethylanilino)methyl]-4-ethyl-1,2,4-triazol-3-yl]sulfanyl]acetate Chemical compound N=1N=C(SCC(=O)OC2CCCCC2)N(CC)C=1CNC1=CC=C(C)C=C1C QKPVMEAYJPEUBD-UHFFFAOYSA-N 0.000 claims 1
• APQWWESOSGWSNQ-UHFFFAOYSA-N cyclohexyl 2-[[5-[(2-chloroanilino)methyl]-4-ethyl-1,2,4-triazol-3-yl]sulfanyl]acetate Chemical compound N=1N=C(SCC(=O)OC2CCCCC2)N(CC)C=1CNC1=CC=CC=C1Cl APQWWESOSGWSNQ-UHFFFAOYSA-N 0.000 claims 1
• MUAVJQMZQZZVSX-UHFFFAOYSA-N cyclohexyl 2-[[5-[(3-chloro-4-methylanilino)methyl]-4-ethyl-1,2,4-triazol-3-yl]sulfanyl]acetate Chemical compound N=1N=C(SCC(=O)OC2CCCCC2)N(CC)C=1CNC1=CC=C(C)C(Cl)=C1 MUAVJQMZQZZVSX-UHFFFAOYSA-N 0.000 claims 1
• WJVDRVKZRSDMSC-UHFFFAOYSA-N cyclohexyl 2-[[5-[(4-chloroanilino)methyl]-4-ethyl-1,2,4-triazol-3-yl]sulfanyl]acetate Chemical compound N=1N=C(SCC(=O)OC2CCCCC2)N(CC)C=1CNC1=CC=C(Cl)C=C1 WJVDRVKZRSDMSC-UHFFFAOYSA-N 0.000 claims 1
• PBGGNZZGJIKBMJ-UHFFFAOYSA-N di(propan-2-yl)azanide Chemical compound CC(C)[N-]C(C)C PBGGNZZGJIKBMJ-UHFFFAOYSA-N 0.000 claims 1
• LQJVHIOSGBLNRR-UHFFFAOYSA-N ethyl 1-(3-cyclopentylpropanoyl)piperidine-3-carboxylate Chemical compound C1C(C(=O)OCC)CCCN1C(=O)CCC1CCCC1 LQJVHIOSGBLNRR-UHFFFAOYSA-N 0.000 claims 1
• ZINWADPKZHBBEQ-UHFFFAOYSA-N ethyl 1-[5-(3-methoxyphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carbonyl]piperidine-4-carboxylate Chemical compound C1CC(C(=O)OCC)CCN1C(=O)C1=C2N=C(C=3C=C(OC)C=CC=3)C=C(C(F)(F)F)N2N=C1 ZINWADPKZHBBEQ-UHFFFAOYSA-N 0.000 claims 1
• LXMMPYWOJVDLMJ-UHFFFAOYSA-N ethyl 1-benzoylpiperidine-2-carboxylate Chemical compound CCOC(=O)C1CCCCN1C(=O)C1=CC=CC=C1 LXMMPYWOJVDLMJ-UHFFFAOYSA-N 0.000 claims 1
• DZTAJGBADYJNRE-UHFFFAOYSA-N ethyl 2-(adamantane-1-carbonylamino)benzoate Chemical compound CCOC(=O)C1=CC=CC=C1NC(=O)C1(C2)CC(C3)CC2CC3C1 DZTAJGBADYJNRE-UHFFFAOYSA-N 0.000 claims 1
• CDBCPHKJBMRFHR-UHFFFAOYSA-N ethyl 2-[(4-benzyl-5-phenyl-1,2,4-triazol-3-yl)sulfanyl]acetate Chemical compound C=1C=CC=CC=1CN1C(SCC(=O)OCC)=NN=C1C1=CC=CC=C1 CDBCPHKJBMRFHR-UHFFFAOYSA-N 0.000 claims 1
• VRMSQWSZMZMFFT-UHFFFAOYSA-N ethyl 2-[6-(3,3,5-trimethyl-7-azabicyclo[3.2.1]octane-7-carbonyl)indol-1-yl]acetate Chemical compound C1C(CC(C)(C)C2)(C)CC2N1C(=O)C1=CC=C2C=CN(CC(=O)OCC)C2=C1 VRMSQWSZMZMFFT-UHFFFAOYSA-N 0.000 claims 1
• AZJBUSLFCKOROQ-UHFFFAOYSA-N ethyl 2-[[4-(2-phenylethyl)-5-pyridin-3-yl-1,2,4-triazol-3-yl]sulfanyl]acetate Chemical compound C=1C=CC=CC=1CCN1C(SCC(=O)OCC)=NN=C1C1=CC=CN=C1 AZJBUSLFCKOROQ-UHFFFAOYSA-N 0.000 claims 1
• RWNCHDWXPXMQKN-UHFFFAOYSA-N ethyl 2-[[4-benzyl-5-(4-methoxyphenyl)-1,2,4-triazol-3-yl]sulfanyl]acetate Chemical compound C=1C=CC=CC=1CN1C(SCC(=O)OCC)=NN=C1C1=CC=C(OC)C=C1 RWNCHDWXPXMQKN-UHFFFAOYSA-N 0.000 claims 1
• MVQVPGRPNVSFJT-UHFFFAOYSA-N ethyl 2-[[4-ethyl-5-(2-methoxyphenyl)-1,2,4-triazol-3-yl]sulfanyl]acetate Chemical compound CCN1C(SCC(=O)OCC)=NN=C1C1=CC=CC=C1OC MVQVPGRPNVSFJT-UHFFFAOYSA-N 0.000 claims 1
• DXAPIMIWEMKPPC-UHFFFAOYSA-N ethyl 2-[benzyl-(4-nitrobenzoyl)amino]acetate Chemical compound C=1C=C([N+]([O-])=O)C=CC=1C(=O)N(CC(=O)OCC)CC1=CC=CC=C1 DXAPIMIWEMKPPC-UHFFFAOYSA-N 0.000 claims 1
• WXWBQJRIFVEWGT-UHFFFAOYSA-N ethyl 2-amino-4-methyl-5-(piperidine-1-carbonyl)thiophene-3-carboxylate Chemical compound CCOC(=O)C1=C(N)SC(C(=O)N2CCCCC2)=C1C WXWBQJRIFVEWGT-UHFFFAOYSA-N 0.000 claims 1
• JJLSXJUIHYRBOV-UHFFFAOYSA-N ethyl 2-amino-5-(azepane-1-carbonyl)-4-methylthiophene-3-carboxylate Chemical compound CCOC(=O)C1=C(N)SC(C(=O)N2CCCCCC2)=C1C JJLSXJUIHYRBOV-UHFFFAOYSA-N 0.000 claims 1
• ONEQTHCBJHMZHZ-UHFFFAOYSA-N ethyl 2-amino-5-(cyclohexylcarbamoyl)-4-methylthiophene-3-carboxylate Chemical compound CCOC(=O)C1=C(N)SC(C(=O)NC2CCCCC2)=C1C ONEQTHCBJHMZHZ-UHFFFAOYSA-N 0.000 claims 1
• XUENQTYWYCCBGX-UHFFFAOYSA-N ethyl 3-[5-(3,3,5-trimethyl-7-azabicyclo[3.2.1]octane-7-carbonyl)indol-1-yl]propanoate Chemical compound C1C(CC(C)(C)C2)(C)CC2N1C(=O)C1=CC=C2N(CCC(=O)OCC)C=CC2=C1 XUENQTYWYCCBGX-UHFFFAOYSA-N 0.000 claims 1
• ZPVCURRGCDGYLA-UHFFFAOYSA-N ethyl 3-[[5-(3,3,5-trimethyl-7-azabicyclo[3.2.1]octane-7-carbonyl)-1H-indole-3-carbonyl]amino]propanoate Chemical compound C1C(CC(C)(C)C2)(C)CC2N1C(=O)C1=CC=C2NC=C(C(=O)NCCC(=O)OCC)C2=C1 ZPVCURRGCDGYLA-UHFFFAOYSA-N 0.000 claims 1
• RLBFFEWLRWWGIW-UHFFFAOYSA-N ethyl 4-(5,7-dimethylpyrazolo[1,5-a]pyrimidine-3-carbonyl)piperazine-1-carboxylate Chemical compound C1CN(C(=O)OCC)CCN1C(=O)C1=C2N=C(C)C=C(C)N2N=C1 RLBFFEWLRWWGIW-UHFFFAOYSA-N 0.000 claims 1
• AEFHHMQJRBXPQR-UHFFFAOYSA-N ethyl 4-[5-(1,3-benzodioxol-5-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carbonyl]piperazine-1-carboxylate Chemical compound C1CN(C(=O)OCC)CCN1C(=O)C1=NN2C(C(F)(F)F)=CC(C=3C=C4OCOC4=CC=3)=NC2=C1 AEFHHMQJRBXPQR-UHFFFAOYSA-N 0.000 claims 1
• BPYGZANGQJXJBZ-UHFFFAOYSA-N ethyl 4-[5-(3-methoxyphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carbonyl]piperazine-1-carboxylate Chemical compound C1CN(C(=O)OCC)CCN1C(=O)C1=C2N=C(C=3C=C(OC)C=CC=3)C=C(C(F)(F)F)N2N=C1 BPYGZANGQJXJBZ-UHFFFAOYSA-N 0.000 claims 1
• WDJQYZSPNXKRJE-UHFFFAOYSA-N ethyl 4-[[2-[(5-cyclohexyl-4-methyl-1,2,4-triazol-3-yl)sulfanyl]acetyl]amino]benzoate Chemical compound C1=CC(C(=O)OCC)=CC=C1NC(=O)CSC(N1C)=NN=C1C1CCCCC1 WDJQYZSPNXKRJE-UHFFFAOYSA-N 0.000 claims 1
• ZUZXVUWNKNIUII-UHFFFAOYSA-N ethyl 4-[[2-[[5-(2-bromophenyl)-4-methyl-1,2,4-triazol-3-yl]sulfanyl]acetyl]amino]benzoate Chemical compound C1=CC(C(=O)OCC)=CC=C1NC(=O)CSC(N1C)=NN=C1C1=CC=CC=C1Br ZUZXVUWNKNIUII-UHFFFAOYSA-N 0.000 claims 1
• APSWRCMFDKPCOL-UHFFFAOYSA-N ethyl 4-[[3-methoxy-5-(pyridine-2-carbonyl)benzoyl]amino]piperidine-1-carboxylate Chemical compound C1CN(C(=O)OCC)CCC1NC(=O)C1=CC(OC)=CC(C(=O)C=2N=CC=CC=2)=C1 APSWRCMFDKPCOL-UHFFFAOYSA-N 0.000 claims 1
• RKEMWDBWPAAWAK-UHFFFAOYSA-N ethyl 6-(3,3,5-trimethyl-7-azabicyclo[3.2.1]octane-7-carbonyl)-1H-indole-3-carboxylate Chemical compound C1C(CC(C)(C)C2)(C)CC2N1C(=O)C1=CC=C2C(C(=O)OCC)=CNC2=C1 RKEMWDBWPAAWAK-UHFFFAOYSA-N 0.000 claims 1
• KBIJOMUAIJBJRE-UHFFFAOYSA-N furan-2-yl-[4-(4-methylphenyl)sulfonylpiperazin-1-yl]methanone Chemical compound C1=CC(C)=CC=C1S(=O)(=O)N1CCN(C(=O)C=2OC=CC=2)CC1 KBIJOMUAIJBJRE-UHFFFAOYSA-N 0.000 claims 1
• DNJFMXHTNUVNII-UHFFFAOYSA-N imidazo[2,1-b][1,3]thiazol-6-yl-(3,3,5-trimethyl-7-azabicyclo[3.2.1]octan-7-yl)methanone Chemical compound C1C2CC(C)(C)CC1(C)CN2C(=O)C1=CN(C=CS2)C2=N1 DNJFMXHTNUVNII-UHFFFAOYSA-N 0.000 claims 1
• 238000004519 manufacturing process Methods 0.000 claims 1
• CKJNUZNMWOVDFN-UHFFFAOYSA-N methanone Chemical compound O=[CH-] CKJNUZNMWOVDFN-UHFFFAOYSA-N 0.000 claims 1
• BQAMRQIYPDLYCD-UHFFFAOYSA-N methyl 1-[7-(difluoromethyl)-5-(4-methoxyphenyl)pyrazolo[1,5-a]pyrimidine-3-carbonyl]indole-3-carboxylate Chemical compound C12=CC=CC=C2C(C(=O)OC)=CN1C(=O)C(=C1N=2)C=NN1C(C(F)F)=CC=2C1=CC=C(OC)C=C1 BQAMRQIYPDLYCD-UHFFFAOYSA-N 0.000 claims 1
• ZJZIVDCVOLKKFB-UHFFFAOYSA-N methyl 2-(adamantane-1-carbonylamino)-3-phenylpropanoate Chemical compound C1C(C2)CC(C3)CC2CC13C(=O)NC(C(=O)OC)CC1=CC=CC=C1 ZJZIVDCVOLKKFB-UHFFFAOYSA-N 0.000 claims 1
• HJWKNMQFBNEIPC-UHFFFAOYSA-N methyl 2-[(2-methoxybenzoyl)amino]-4-methyl-5-(piperidine-1-carbonyl)thiophene-3-carboxylate Chemical compound COC(=O)C=1C(C)=C(C(=O)N2CCCCC2)SC=1NC(=O)C1=CC=CC=C1OC HJWKNMQFBNEIPC-UHFFFAOYSA-N 0.000 claims 1
• FBSJQHFZRYKPQK-UHFFFAOYSA-N methyl 2-[(3-fluorobenzoyl)amino]-4-methyl-5-(piperidine-1-carbonyl)thiophene-3-carboxylate Chemical compound COC(=O)C=1C(C)=C(C(=O)N2CCCCC2)SC=1NC(=O)C1=CC=CC(F)=C1 FBSJQHFZRYKPQK-UHFFFAOYSA-N 0.000 claims 1
• XVYXYBDZHBRSDJ-UHFFFAOYSA-N methyl 2-[[2-[[4-ethyl-5-(3-methylphenyl)-1,2,4-triazol-3-yl]sulfanyl]acetyl]amino]benzoate Chemical compound N=1N=C(C=2C=C(C)C=CC=2)N(CC)C=1SCC(=O)NC1=CC=CC=C1C(=O)OC XVYXYBDZHBRSDJ-UHFFFAOYSA-N 0.000 claims 1
• PGWMMDGZOLEYMY-UHFFFAOYSA-N methyl 2-[[2-[[4-methyl-5-(3-methylphenyl)-1,2,4-triazol-3-yl]sulfanyl]acetyl]amino]benzoate Chemical compound COC(=O)C1=CC=CC=C1NC(=O)CSC(N1C)=NN=C1C1=CC=CC(C)=C1 PGWMMDGZOLEYMY-UHFFFAOYSA-N 0.000 claims 1
• LLGCIOWMDCLFGV-UHFFFAOYSA-N methyl 2-[[3-(4-methylphenyl)adamantane-1-carbonyl]amino]propanoate Chemical compound C1C(C(=O)NC(C)C(=O)OC)(C2)CC(C3)CC1CC32C1=CC=C(C)C=C1 LLGCIOWMDCLFGV-UHFFFAOYSA-N 0.000 claims 1
• ANQMBDBYRBFSQZ-UHFFFAOYSA-N methyl 3-[6-(3,3,5-trimethyl-7-azabicyclo[3.2.1]octane-7-carbonyl)-1H-benzimidazol-2-yl]benzoate Chemical compound COC(=O)C1=CC=CC(C=2NC3=CC=C(C=C3N=2)C(=O)N2C3CC(CC(C)(C)C3)(C)C2)=C1 ANQMBDBYRBFSQZ-UHFFFAOYSA-N 0.000 claims 1
• ONUFFCAYSOHVIC-UHFFFAOYSA-N methyl 3-[[5-(3,3,5-trimethyl-7-azabicyclo[3.2.1]octane-7-carbonyl)indol-1-yl]methyl]benzoate Chemical compound COC(=O)C1=CC=CC(CN2C3=CC=C(C=C3C=C2)C(=O)N2C3CC(CC(C)(C)C3)(C)C2)=C1 ONUFFCAYSOHVIC-UHFFFAOYSA-N 0.000 claims 1
• DXZPXECYINTUDB-UHFFFAOYSA-N methyl 4-[(4-ethyl-5-naphthalen-1-yl-1,2,4-triazol-3-yl)sulfanylmethyl]benzoate Chemical compound N=1N=C(C=2C3=CC=CC=C3C=CC=2)N(CC)C=1SCC1=CC=C(C(=O)OC)C=C1 DXZPXECYINTUDB-UHFFFAOYSA-N 0.000 claims 1
• OTMTWNJAHZRMCH-UHFFFAOYSA-N methyl 4-[(4-ethyl-5-pyridin-2-yl-1,2,4-triazol-3-yl)sulfanylmethyl]benzoate Chemical compound N=1N=C(C=2N=CC=CC=2)N(CC)C=1SCC1=CC=C(C(=O)OC)C=C1 OTMTWNJAHZRMCH-UHFFFAOYSA-N 0.000 claims 1
• PQKXWFNDCWLHCO-UHFFFAOYSA-N methyl 4-[(4-ethyl-5-pyridin-3-yl-1,2,4-triazol-3-yl)sulfanylmethyl]benzoate Chemical compound N=1N=C(C=2C=NC=CC=2)N(CC)C=1SCC1=CC=C(C(=O)OC)C=C1 PQKXWFNDCWLHCO-UHFFFAOYSA-N 0.000 claims 1
• BJMZPFJOFOIPTC-UHFFFAOYSA-N methyl 4-[(4-ethyl-5-pyridin-4-yl-1,2,4-triazol-3-yl)sulfanylmethyl]benzoate Chemical compound N=1N=C(C=2C=CN=CC=2)N(CC)C=1SCC1=CC=C(C(=O)OC)C=C1 BJMZPFJOFOIPTC-UHFFFAOYSA-N 0.000 claims 1
• WEZWMAPLBZLUEG-UHFFFAOYSA-N methyl 4-[(4-ethyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanylmethyl]benzoate Chemical compound N=1N=C(C=2SC=CC=2)N(CC)C=1SCC1=CC=C(C(=O)OC)C=C1 WEZWMAPLBZLUEG-UHFFFAOYSA-N 0.000 claims 1
• WRHXNHYSDZMSOV-UHFFFAOYSA-N methyl 4-[[2-[[4-methyl-5-(2-methylphenyl)-1,2,4-triazol-3-yl]sulfanyl]acetyl]amino]benzoate Chemical compound C1=CC(C(=O)OC)=CC=C1NC(=O)CSC(N1C)=NN=C1C1=CC=CC=C1C WRHXNHYSDZMSOV-UHFFFAOYSA-N 0.000 claims 1
• MQQQHWSZLZEKBK-UHFFFAOYSA-N methyl 4-[[2-[[5-(2-bromophenyl)-4-ethyl-1,2,4-triazol-3-yl]sulfanyl]acetyl]amino]benzoate Chemical compound N=1N=C(C=2C(=CC=CC=2)Br)N(CC)C=1SCC(=O)NC1=CC=C(C(=O)OC)C=C1 MQQQHWSZLZEKBK-UHFFFAOYSA-N 0.000 claims 1
• PTRXAQBPTBMLQR-UHFFFAOYSA-N methyl 4-[[2-[[5-(2-bromophenyl)-4-methyl-1,2,4-triazol-3-yl]sulfanyl]acetyl]amino]benzoate Chemical compound C1=CC(C(=O)OC)=CC=C1NC(=O)CSC(N1C)=NN=C1C1=CC=CC=C1Br PTRXAQBPTBMLQR-UHFFFAOYSA-N 0.000 claims 1
• XJCOOCQMCVDBLZ-UHFFFAOYSA-N methyl 4-[[4-ethyl-5-(2-methoxyphenyl)-1,2,4-triazol-3-yl]sulfanylmethyl]benzoate Chemical compound N=1N=C(C=2C(=CC=CC=2)OC)N(CC)C=1SCC1=CC=C(C(=O)OC)C=C1 XJCOOCQMCVDBLZ-UHFFFAOYSA-N 0.000 claims 1
• AYWMHTZPTFMTIK-UHFFFAOYSA-N methyl 4-[[4-ethyl-5-(2-methylsulfanylpyridin-3-yl)-1,2,4-triazol-3-yl]sulfanylmethyl]benzoate Chemical compound N=1N=C(C=2C(=NC=CC=2)SC)N(CC)C=1SCC1=CC=C(C(=O)OC)C=C1 AYWMHTZPTFMTIK-UHFFFAOYSA-N 0.000 claims 1
• RESQYUISXLOHOX-UHFFFAOYSA-N methyl 4-[[4-ethyl-5-(2-phenoxyphenyl)-1,2,4-triazol-3-yl]sulfanylmethyl]benzoate Chemical compound N=1N=C(C=2C(=CC=CC=2)OC=2C=CC=CC=2)N(CC)C=1SCC1=CC=C(C(=O)OC)C=C1 RESQYUISXLOHOX-UHFFFAOYSA-N 0.000 claims 1
• WHGLCEFWBQUWMW-UHFFFAOYSA-N methyl 4-[[4-ethyl-5-(4-methoxyphenyl)-1,2,4-triazol-3-yl]sulfanylmethyl]benzoate Chemical compound N=1N=C(C=2C=CC(OC)=CC=2)N(CC)C=1SCC1=CC=C(C(=O)OC)C=C1 WHGLCEFWBQUWMW-UHFFFAOYSA-N 0.000 claims 1
• JZNXWDJIFAVCGW-UHFFFAOYSA-N methyl 4-[[4-ethyl-5-(5-methylthiophen-2-yl)-1,2,4-triazol-3-yl]sulfanylmethyl]benzoate Chemical compound N=1N=C(C=2SC(C)=CC=2)N(CC)C=1SCC1=CC=C(C(=O)OC)C=C1 JZNXWDJIFAVCGW-UHFFFAOYSA-N 0.000 claims 1
• WJORAEFMESMYRR-UHFFFAOYSA-N methyl 4-[[4-ethyl-5-[1-phenyl-5-(trifluoromethyl)pyrazol-4-yl]-1,2,4-triazol-3-yl]sulfanylmethyl]benzoate Chemical compound N=1N=C(C2=C(N(N=C2)C=2C=CC=CC=2)C(F)(F)F)N(CC)C=1SCC1=CC=C(C(=O)OC)C=C1 WJORAEFMESMYRR-UHFFFAOYSA-N 0.000 claims 1
• FNUVMUDNXXDPHH-UHFFFAOYSA-N methyl 4-[[5-(1,3-benzodioxol-5-yl)-4-ethyl-1,2,4-triazol-3-yl]sulfanylmethyl]benzoate Chemical compound N=1N=C(C=2C=C3OCOC3=CC=2)N(CC)C=1SCC1=CC=C(C(=O)OC)C=C1 FNUVMUDNXXDPHH-UHFFFAOYSA-N 0.000 claims 1
• QGKZADYDXZUJFG-UHFFFAOYSA-N methyl 4-[[5-(1-benzothiophen-2-yl)-4-ethyl-1,2,4-triazol-3-yl]sulfanylmethyl]benzoate Chemical compound N=1N=C(C=2SC3=CC=CC=C3C=2)N(CC)C=1SCC1=CC=C(C(=O)OC)C=C1 QGKZADYDXZUJFG-UHFFFAOYSA-N 0.000 claims 1
• JEVWSXYOUBTXQJ-UHFFFAOYSA-N methyl 4-[[5-(3-chloro-4-methylthiophen-2-yl)-4-ethyl-1,2,4-triazol-3-yl]sulfanylmethyl]benzoate Chemical compound N=1N=C(C2=C(C(C)=CS2)Cl)N(CC)C=1SCC1=CC=C(C(=O)OC)C=C1 JEVWSXYOUBTXQJ-UHFFFAOYSA-N 0.000 claims 1
• YFOVORSXBYVNRX-UHFFFAOYSA-N methyl 4-[[5-(4-chlorophenyl)-4-ethyl-1,2,4-triazol-3-yl]sulfanylmethyl]benzoate Chemical compound N=1N=C(C=2C=CC(Cl)=CC=2)N(CC)C=1SCC1=CC=C(C(=O)OC)C=C1 YFOVORSXBYVNRX-UHFFFAOYSA-N 0.000 claims 1
• FYDNCJPPYJAAJD-UHFFFAOYSA-N methyl 4-[[5-(5-chlorothiophen-2-yl)-4-ethyl-1,2,4-triazol-3-yl]sulfanylmethyl]benzoate Chemical compound N=1N=C(C=2SC(Cl)=CC=2)N(CC)C=1SCC1=CC=C(C(=O)OC)C=C1 FYDNCJPPYJAAJD-UHFFFAOYSA-N 0.000 claims 1
• FWBBMKQKFJQKIC-UHFFFAOYSA-N methyl 4-[[5-[4-(2,5-dimethylpyrrol-1-yl)phenyl]-4-ethyl-1,2,4-triazol-3-yl]sulfanylmethyl]benzoate Chemical compound N=1N=C(C=2C=CC(=CC=2)N2C(=CC=C2C)C)N(CC)C=1SCC1=CC=C(C(=O)OC)C=C1 FWBBMKQKFJQKIC-UHFFFAOYSA-N 0.000 claims 1
• QPCZVFDRLFBYKQ-UHFFFAOYSA-N methyl 7-methyl-5-phenylpyrazolo[1,5-a]pyrimidine-2-carboxylate Chemical compound C1=C(C)N2N=C(C(=O)OC)C=C2N=C1C1=CC=CC=C1 QPCZVFDRLFBYKQ-UHFFFAOYSA-N 0.000 claims 1
• GPGKYRAMDAROJU-UHFFFAOYSA-N morpholin-4-yl-[5-(4-nitrophenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]methanone Chemical compound C1=CC([N+](=O)[O-])=CC=C1C1=NC2=CC(C(=O)N3CCOCC3)=NN2C(C(F)(F)F)=C1 GPGKYRAMDAROJU-UHFFFAOYSA-N 0.000 claims 1
• VMIRXFZOESFYDS-UHFFFAOYSA-N morpholin-4-yl-[5-phenyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-3-yl]methanone Chemical compound C1=NN2C(C(F)(F)F)=CC(C=3C=CC=CC=3)=NC2=C1C(=O)N1CCOCC1 VMIRXFZOESFYDS-UHFFFAOYSA-N 0.000 claims 1
• JFJFMNYEFJABEO-UHFFFAOYSA-N morpholin-4-yl-[5-thiophen-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]methanone Chemical compound N=1N2C(C(F)(F)F)=CC(C=3SC=CC=3)=NC2=CC=1C(=O)N1CCOCC1 JFJFMNYEFJABEO-UHFFFAOYSA-N 0.000 claims 1
• UANPVYJHWJUJGP-UHFFFAOYSA-N morpholin-4-yl-[7-(trifluoromethyl)-5-(3,4,5-trimethoxyphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]methanone Chemical compound COC1=C(OC)C(OC)=CC(C2=NC3=C(C(=O)N4CCOCC4)C=NN3C(=C2)C(F)(F)F)=C1 UANPVYJHWJUJGP-UHFFFAOYSA-N 0.000 claims 1
• YTRRLRILJSLFDB-UHFFFAOYSA-N pentyl 2-(N-benzoyl-3-chloro-4-fluoroanilino)propanoate Chemical compound C=1C=C(F)C(Cl)=CC=1N(C(C)C(=O)OCCCCC)C(=O)C1=CC=CC=C1 YTRRLRILJSLFDB-UHFFFAOYSA-N 0.000 claims 1
• VBARFZRVWLOROJ-UHFFFAOYSA-N phenyl-(3,3,5-trimethyl-7-azabicyclo[3.2.1]octan-7-yl)methanone Chemical compound C1C(C)(C)CC(C)(C2)CC1N2C(=O)C1=CC=CC=C1 VBARFZRVWLOROJ-UHFFFAOYSA-N 0.000 claims 1
• WRTGTGCLLZPFPF-UHFFFAOYSA-N phenyl-[1-(thiophene-2-carbonyl)piperidin-4-yl]methanone Chemical compound C=1C=CSC=1C(=O)N(CC1)CCC1C(=O)C1=CC=CC=C1 WRTGTGCLLZPFPF-UHFFFAOYSA-N 0.000 claims 1
• ZUPGHKKHKOINAJ-UHFFFAOYSA-N phenyl-[4-[5-phenyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carbonyl]piperazin-1-yl]methanone Chemical compound N=1N2C(C(F)(F)F)=CC(C=3C=CC=CC=3)=NC2=CC=1C(=O)N(CC1)CCN1C(=O)C1=CC=CC=C1 ZUPGHKKHKOINAJ-UHFFFAOYSA-N 0.000 claims 1
• VCYQVRXGIDGRTL-UHFFFAOYSA-N piperidin-1-yl-[5-thiophen-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]methanone Chemical compound N=1N2C(C(F)(F)F)=CC(C=3SC=CC=3)=NC2=CC=1C(=O)N1CCCCC1 VCYQVRXGIDGRTL-UHFFFAOYSA-N 0.000 claims 1
• MNBZNCJDKRGQKO-UHFFFAOYSA-N piperidin-1-yl-[7-(trifluoromethyl)-5-(3,4,5-trimethoxyphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]methanone Chemical compound COC1=C(OC)C(OC)=CC(C2=NC3=C(C(=O)N4CCCCC4)C=NN3C(=C2)C(F)(F)F)=C1 MNBZNCJDKRGQKO-UHFFFAOYSA-N 0.000 claims 1
• LITSALPMELKAAW-UHFFFAOYSA-N propan-2-yl 2-(cyclohexylcarbamoyl)bicyclo[2.2.1]hept-5-ene-3-carboxylate Chemical compound CC(C)OC(=O)C1C(C=C2)CC2C1C(=O)NC1CCCCC1 LITSALPMELKAAW-UHFFFAOYSA-N 0.000 claims 1
• DUJOYMKMKKMNCU-UHFFFAOYSA-N propan-2-yl 2-[[5-(2-methoxyphenyl)-4-methyl-1,2,4-triazol-3-yl]sulfanyl]acetate Chemical compound COC1=CC=CC=C1C1=NN=C(SCC(=O)OC(C)C)N1C DUJOYMKMKKMNCU-UHFFFAOYSA-N 0.000 claims 1
• ZMVANDXKCVEGNX-UHFFFAOYSA-N propan-2-yl 2-[[5-[(2-chloroanilino)methyl]-4-ethyl-1,2,4-triazol-3-yl]sulfanyl]acetate Chemical compound N1=C(SCC(=O)OC(C)C)N(CC)C(CNC=2C(=CC=CC=2)Cl)=N1 ZMVANDXKCVEGNX-UHFFFAOYSA-N 0.000 claims 1
• KWTOYIUPZVTSRN-UHFFFAOYSA-N pyrazolo[1,5-a]pyridin-3-yl-(3,3,5-trimethyl-7-azabicyclo[3.2.1]octan-7-yl)methanone Chemical compound C1=NN2C=CC=CC2=C1C(=O)N(C1)C2CC1(C)CC(C)(C)C2 KWTOYIUPZVTSRN-UHFFFAOYSA-N 0.000 claims 1
• UVUVEDLXWXTLBP-UHFFFAOYSA-N quinolin-2-yl-(3,3,5-trimethyl-7-azabicyclo[3.2.1]octan-7-yl)methanone Chemical compound C1=CC=CC2=NC(C(=O)N3C4CC(CC(C)(C)C4)(C3)C)=CC=C21 UVUVEDLXWXTLBP-UHFFFAOYSA-N 0.000 claims 1
• 239000000126 substance Substances 0.000 claims 1
• GYLMFXAMZWMNAV-UHFFFAOYSA-N tert-butyl 2-[[3-(3,3,5-trimethyl-7-azabicyclo[3.2.1]octane-7-carbonyl)-1H-indol-6-yl]oxy]acetate Chemical compound C1C(CC(C)(C)C2)(C)CC2N1C(=O)C1=CNC2=CC(OCC(=O)OC(C)(C)C)=CC=C21 GYLMFXAMZWMNAV-UHFFFAOYSA-N 0.000 claims 1
• CBVRKNSUJSDWJS-UHFFFAOYSA-N tert-butylazanide Chemical compound CC(C)(C)[NH-] CBVRKNSUJSDWJS-UHFFFAOYSA-N 0.000 claims 1