JP2006521334A5 - - Google Patents
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- Publication number
- JP2006521334A5 JP2006521334A5 JP2006505750A JP2006505750A JP2006521334A5 JP 2006521334 A5 JP2006521334 A5 JP 2006521334A5 JP 2006505750 A JP2006505750 A JP 2006505750A JP 2006505750 A JP2006505750 A JP 2006505750A JP 2006521334 A5 JP2006521334 A5 JP 2006521334A5
- Authority
- JP
- Japan
- Prior art keywords
- wax
- lipid
- solid particles
- solid
- mixture
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000002245 particle Substances 0.000 claims description 20
- 150000002632 lipids Chemical class 0.000 claims description 19
- 239000007787 solid Substances 0.000 claims description 18
- 239000000203 mixture Substances 0.000 claims description 11
- 235000014113 dietary fatty acids Nutrition 0.000 claims description 8
- 239000000194 fatty acid Substances 0.000 claims description 8
- 229930195729 fatty acid Natural products 0.000 claims description 8
- 150000004665 fatty acids Chemical class 0.000 claims description 8
- 239000004480 active ingredient Substances 0.000 claims description 6
- 239000003349 gelling agent Substances 0.000 claims description 6
- 230000002209 hydrophobic effect Effects 0.000 claims description 6
- 238000000034 method Methods 0.000 claims description 4
- 239000004094 surface-active agent Substances 0.000 claims description 4
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 3
- 239000006185 dispersion Substances 0.000 claims description 2
- 239000003995 emulsifying agent Substances 0.000 claims description 2
- 238000007711 solidification Methods 0.000 claims description 2
- 230000008023 solidification Effects 0.000 claims description 2
- 239000002904 solvent Substances 0.000 claims description 2
- 239000001993 wax Substances 0.000 claims 11
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims 4
- 230000008018 melting Effects 0.000 claims 3
- 238000002844 melting Methods 0.000 claims 3
- 235000013871 bee wax Nutrition 0.000 claims 2
- 239000012166 beeswax Substances 0.000 claims 2
- POULHZVOKOAJMA-UHFFFAOYSA-N dodecanoic acid Chemical compound CCCCCCCCCCCC(O)=O POULHZVOKOAJMA-UHFFFAOYSA-N 0.000 claims 2
- IPCSVZSSVZVIGE-UHFFFAOYSA-N hexadecanoic acid Chemical compound CCCCCCCCCCCCCCCC(O)=O IPCSVZSSVZVIGE-UHFFFAOYSA-N 0.000 claims 2
- 239000012178 vegetable wax Substances 0.000 claims 2
- DSEKYWAQQVUQTP-XEWMWGOFSA-N (2r,4r,4as,6as,6as,6br,8ar,12ar,14as,14bs)-2-hydroxy-4,4a,6a,6b,8a,11,11,14a-octamethyl-2,4,5,6,6a,7,8,9,10,12,12a,13,14,14b-tetradecahydro-1h-picen-3-one Chemical compound C([C@H]1[C@]2(C)CC[C@@]34C)C(C)(C)CC[C@]1(C)CC[C@]2(C)[C@H]4CC[C@@]1(C)[C@H]3C[C@@H](O)C(=O)[C@@H]1C DSEKYWAQQVUQTP-XEWMWGOFSA-N 0.000 claims 1
- WRIDQFICGBMAFQ-UHFFFAOYSA-N (E)-8-Octadecenoic acid Natural products CCCCCCCCCC=CCCCCCCC(O)=O WRIDQFICGBMAFQ-UHFFFAOYSA-N 0.000 claims 1
- LQJBNNIYVWPHFW-UHFFFAOYSA-N 20:1omega9c fatty acid Natural products CCCCCCCCCCC=CCCCCCCCC(O)=O LQJBNNIYVWPHFW-UHFFFAOYSA-N 0.000 claims 1
- QSBYPNXLFMSGKH-UHFFFAOYSA-N 9-Heptadecensaeure Natural products CCCCCCCC=CCCCCCCCC(O)=O QSBYPNXLFMSGKH-UHFFFAOYSA-N 0.000 claims 1
- 241000196324 Embryophyta Species 0.000 claims 1
- 239000005639 Lauric acid Substances 0.000 claims 1
- 240000007817 Olea europaea Species 0.000 claims 1
- 239000005642 Oleic acid Substances 0.000 claims 1
- ZQPPMHVWECSIRJ-UHFFFAOYSA-N Oleic acid Natural products CCCCCCCCC=CCCCCCCCC(O)=O ZQPPMHVWECSIRJ-UHFFFAOYSA-N 0.000 claims 1
- 240000007594 Oryza sativa Species 0.000 claims 1
- 235000007164 Oryza sativa Nutrition 0.000 claims 1
- 235000019482 Palm oil Nutrition 0.000 claims 1
- 235000021314 Palmitic acid Nutrition 0.000 claims 1
- 239000012164 animal wax Substances 0.000 claims 1
- 239000004204 candelilla wax Substances 0.000 claims 1
- 235000013868 candelilla wax Nutrition 0.000 claims 1
- 229940073532 candelilla wax Drugs 0.000 claims 1
- 125000004432 carbon atom Chemical group C* 0.000 claims 1
- 125000002057 carboxymethyl group Chemical group [H]OC(=O)C([H])([H])[*] 0.000 claims 1
- 239000004203 carnauba wax Substances 0.000 claims 1
- 235000013869 carnauba wax Nutrition 0.000 claims 1
- 239000000679 carrageenan Substances 0.000 claims 1
- 229920001525 carrageenan Polymers 0.000 claims 1
- 229940113118 carrageenan Drugs 0.000 claims 1
- 235000010418 carrageenan Nutrition 0.000 claims 1
- 229940110456 cocoa butter Drugs 0.000 claims 1
- 235000019868 cocoa butter Nutrition 0.000 claims 1
- 239000002537 cosmetic Substances 0.000 claims 1
- 238000001035 drying Methods 0.000 claims 1
- 235000019197 fats Nutrition 0.000 claims 1
- 235000013305 food Nutrition 0.000 claims 1
- 150000004676 glycans Chemical class 0.000 claims 1
- IUJAMGNYPWYUPM-UHFFFAOYSA-N hentriacontane Chemical compound CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC IUJAMGNYPWYUPM-UHFFFAOYSA-N 0.000 claims 1
- QXJSBBXBKPUZAA-UHFFFAOYSA-N isooleic acid Natural products CCCCCCCC=CCCCCCCCCC(O)=O QXJSBBXBKPUZAA-UHFFFAOYSA-N 0.000 claims 1
- 229940119170 jojoba wax Drugs 0.000 claims 1
- 239000012184 mineral wax Substances 0.000 claims 1
- WQEPLUUGTLDZJY-UHFFFAOYSA-N n-Pentadecanoic acid Natural products CCCCCCCCCCCCCCC(O)=O WQEPLUUGTLDZJY-UHFFFAOYSA-N 0.000 claims 1
- 239000003921 oil Substances 0.000 claims 1
- 235000019198 oils Nutrition 0.000 claims 1
- ZQPPMHVWECSIRJ-KTKRTIGZSA-N oleic acid Chemical compound CCCCCCCC\C=C/CCCCCCCC(O)=O ZQPPMHVWECSIRJ-KTKRTIGZSA-N 0.000 claims 1
- 239000002540 palm oil Substances 0.000 claims 1
- 229920000642 polymer Polymers 0.000 claims 1
- 239000005017 polysaccharide Substances 0.000 claims 1
- 229920001282 polysaccharide Polymers 0.000 claims 1
- 238000002360 preparation method Methods 0.000 claims 1
- 235000009566 rice Nutrition 0.000 claims 1
- 238000007873 sieving Methods 0.000 claims 1
- 238000003756 stirring Methods 0.000 claims 1
- TUNFSRHWOTWDNC-HKGQFRNVSA-N tetradecanoic acid Chemical compound CCCCCCCCCCCCC[14C](O)=O TUNFSRHWOTWDNC-HKGQFRNVSA-N 0.000 claims 1
- 239000002562 thickening agent Substances 0.000 claims 1
- UFTFJSFQGQCHQW-UHFFFAOYSA-N triformin Chemical compound O=COCC(OC=O)COC=O UFTFJSFQGQCHQW-UHFFFAOYSA-N 0.000 claims 1
- 238000005406 washing Methods 0.000 claims 1
- UHVMMEOXYDMDKI-JKYCWFKZSA-L zinc;1-(5-cyanopyridin-2-yl)-3-[(1s,2s)-2-(6-fluoro-2-hydroxy-3-propanoylphenyl)cyclopropyl]urea;diacetate Chemical compound [Zn+2].CC([O-])=O.CC([O-])=O.CCC(=O)C1=CC=C(F)C([C@H]2[C@H](C2)NC(=O)NC=2N=CC(=CC=2)C#N)=C1O UHVMMEOXYDMDKI-JKYCWFKZSA-L 0.000 claims 1
- 238000005243 fluidization Methods 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR03/03568 | 2003-03-24 | ||
| FR0303568A FR2852843B1 (fr) | 2003-03-24 | 2003-03-24 | Systeme galenique permettant le masquage du gout |
| PCT/FR2004/000729 WO2004084856A2 (fr) | 2003-03-24 | 2004-03-24 | Nouveau systeme galenique pour le transport d’actif, procede de preparation et utilisation |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2006521334A JP2006521334A (ja) | 2006-09-21 |
| JP2006521334A5 true JP2006521334A5 (enExample) | 2011-03-31 |
| JP5072355B2 JP5072355B2 (ja) | 2012-11-14 |
Family
ID=32947122
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006505750A Expired - Fee Related JP5072355B2 (ja) | 2003-03-24 | 2004-03-24 | 有効成分輸送のための新規なガレヌス製剤系、調製方法及び使用 |
Country Status (10)
| Country | Link |
|---|---|
| US (3) | US20070116728A1 (enExample) |
| EP (1) | EP1605918B1 (enExample) |
| JP (1) | JP5072355B2 (enExample) |
| KR (1) | KR20060012576A (enExample) |
| AU (1) | AU2004224601A1 (enExample) |
| CA (1) | CA2519962C (enExample) |
| FR (1) | FR2852843B1 (enExample) |
| MX (1) | MXPA05010217A (enExample) |
| NZ (1) | NZ542590A (enExample) |
| WO (1) | WO2004084856A2 (enExample) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2852843B1 (fr) * | 2003-03-24 | 2008-05-23 | Karim Ioualalen | Systeme galenique permettant le masquage du gout |
| FR2879930B1 (fr) * | 2004-12-23 | 2007-08-31 | Oralance Pharma Sa | Nouveau systeme galenique pour le transport d'actif, procede de preparation et utilisation |
| FR2913884A1 (fr) * | 2007-03-21 | 2008-09-26 | Oralance Pharma Sa | Systeme galenique hydrophobe non ionisable |
| US8613956B2 (en) * | 2008-06-23 | 2013-12-24 | International Flora Technologies, Ltd. | Cosmetic particles that transform from hard to soft particles comprising hydrogenated long-chain triglyceride oils |
| FR2935270A1 (fr) * | 2008-08-28 | 2010-03-05 | Oralance Pharma | Composition pharmaceutique de temozolomide pour usage pediatrique |
| CN104736229B (zh) * | 2012-10-18 | 2017-05-03 | 帝斯曼知识产权资产管理有限公司 | 包含类胡萝卜素的珠粒 |
| US20160000714A1 (en) | 2013-03-06 | 2016-01-07 | Capsugel Belgium Nv | Curcumin solid lipid particles and methods for their preparation and use |
| EP3154529B1 (en) | 2014-06-10 | 2020-07-08 | Capsugel Belgium NV | Orally disintegrating tablet containing solid lipid particles and methods for their preparation and use |
| US11324699B2 (en) | 2014-12-04 | 2022-05-10 | Capsugel Belgium Nv | Lipid multiparticulate formulations |
| US9744221B2 (en) | 2014-12-23 | 2017-08-29 | Synthetic Biologics, Inc. | Method and compositions for inhibiting or preventing adverse effects of oral antibiotics |
| EP3551164B1 (fr) * | 2016-12-08 | 2021-03-31 | Salsarulo Pharma | Médicament oral comprenant un laxatif osmotique incorporé dans une matrice à base de matières grasses végétales |
| FR3059903B1 (fr) * | 2016-12-08 | 2019-03-22 | Salsarulo Pharma | Medicament oral comprenant un laxatif osmotique incorpore dans une matrice a base de matieres grasses vegetales |
| US10639607B2 (en) | 2017-06-16 | 2020-05-05 | Matralix Pte Ltd | Systems and methods for preparing wax and lipid particles |
| CN111328284A (zh) | 2017-08-07 | 2020-06-23 | 芬奇治疗公司 | 用于维持和恢复健康的肠道屏障的组合物和方法 |
| US11338020B2 (en) | 2018-01-09 | 2022-05-24 | Synthetic Biologics, Inc. | Alkaline phosphatase agents for treatment of neurodevelopmental disorders |
| WO2019165285A1 (en) | 2018-02-23 | 2019-08-29 | Crestovo Holdings Llc | Microbiome related immunotherapies |
| FR3078630B1 (fr) * | 2018-03-08 | 2021-05-14 | Karim Ioualalen | Mode de formulation sous forme de solide divise hydrophobe |
| EP3773686B1 (en) | 2018-03-20 | 2023-06-07 | Theriva Biologics, Inc. | Alkaline phosphatase agents for treatment of radiation disorders |
| ES3032290T3 (en) | 2018-03-20 | 2025-07-16 | Theriva Biologics Inc | Intestinal alkaline phosphatase formulations |
| FR3079146B1 (fr) * | 2018-03-23 | 2020-04-17 | Karim Ioualalen | Formulation gastroprotectrice de complexes d’enzymes permettant de restaurer la fonction digestive. |
| WO2021011754A1 (en) | 2019-07-18 | 2021-01-21 | Synthetic Biologics, Inc. | Intestinal alkaline phosphatase-based treatments of metabolic disorders |
| WO2021016081A1 (en) | 2019-07-19 | 2021-01-28 | Finch Therapeutics Holdings Llc. | Methods and products for treatment of gastrointestinal disorders |
| WO2021050965A1 (en) | 2019-09-13 | 2021-03-18 | Crestovo Holdings Llc | Compositions and methods for treating autism spectrum disorder |
| AU2020366529A1 (en) | 2019-10-18 | 2022-05-19 | Finch Therapeutics Holdings Llc | Compositions and methods for delivering a bacterial metabolite to a subject |
| WO2021097288A1 (en) | 2019-11-15 | 2021-05-20 | Finch Therapeutics Holdings Llc | Compositions and methods for treating neurodegenerative diseases |
| WO2021142353A1 (en) | 2020-01-10 | 2021-07-15 | Finch Therapeutics Holdings Llc | Compositions and methods for treating hepatitis b (hbv) and hepatitis d (hdv) |
| WO2021142358A1 (en) | 2020-01-10 | 2021-07-15 | Finch Therapeutics Holdings Llc | Compositions and methods for treating hepatic encephalopathy (he) |
| WO2021142347A1 (en) | 2020-01-10 | 2021-07-15 | Finch Therapeutics Holdings Llc | Compositions and methods for non-alcoholic steatohepatitis (nash) |
| US20230201265A1 (en) | 2020-03-31 | 2023-06-29 | Finch Therapeutics Holdings Llc | Compositions comprising non-viable fecal microbiota and methods of use thereof |
| US20240263251A1 (en) | 2021-02-19 | 2024-08-08 | Finch Therapeutics Holdings Llc | Compositions and methods for providing secondary bile acids to a subject |
| CN113308045B (zh) * | 2021-05-28 | 2022-03-22 | 宁波市鑫晟工贸实业有限公司 | 一种抗老化的塑料盒及其制备方法 |
| IT202100014330A1 (it) * | 2021-06-01 | 2022-12-01 | The Ubeauty Com Llc | Prodotto per la cura della pelle e procedimento per la sua realizzazione. |
| US20230256056A1 (en) * | 2022-02-11 | 2023-08-17 | Insitu Biologics, Inc. | Sustained release cancer therapeutics formulations |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3146167A (en) * | 1961-10-05 | 1964-08-25 | Smith Kline French Lab | Method of preparing sustained release pellets and products thereof |
| US4132753A (en) * | 1965-02-12 | 1979-01-02 | American Cyanamid Company | Process for preparing oral sustained release granules |
| GB1323161A (en) * | 1970-02-16 | 1973-07-11 | Wyeth John & Brother Ltd | Penicillin composition |
| US4132375A (en) * | 1976-01-21 | 1979-01-02 | The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration | Vortex-lift roll-control device |
| US4590062A (en) * | 1984-04-16 | 1986-05-20 | Tech Trade Corp. | Dry direct compression compositions for controlled release dosage forms |
| JPS63301815A (ja) * | 1987-01-29 | 1988-12-08 | Taisho Pharmaceut Co Ltd | 経口製剤の製造方法 |
| JP2700662B2 (ja) * | 1988-06-22 | 1998-01-21 | 大正製薬株式会社 | 被覆製剤 |
| JPH02200639A (ja) * | 1989-01-31 | 1990-08-08 | Shinfusou Seiyaku Kk | 脂質被覆細菌製剤 |
| IT1229856B (it) | 1989-04-20 | 1991-09-13 | Recordati Chem Pharm | Compresse a rilascio controllato contenenti flavossato. |
| US5213810A (en) | 1990-03-30 | 1993-05-25 | American Cyanamid Company | Stable compositions for parenteral administration and method of making same |
| ATE134873T1 (de) | 1991-07-23 | 1996-03-15 | American Cyanamid Co | Stabile zusammensetzungen für parenterale verabrechung und ihre verwendung |
| DE4131562A1 (de) | 1991-09-18 | 1993-03-25 | Medac Klinische Spezialpraep | Arzneistofftraeger aus festen lipidteilchen-feste lipidnanosphaeren (sln) |
| KR950703935A (ko) * | 1992-11-30 | 1995-11-17 | 밋첼 아이, 커시너 | 맛을 차단하는 약제학적 조성물 |
| CA2091152C (en) | 1993-03-05 | 2005-05-03 | Kirsten Westesen | Solid lipid particles, particles of bioactive agents and methods for the manfuacture and use thereof |
| DE4308282C2 (de) | 1993-03-16 | 1994-12-22 | Beiersdorf Ag | Vorzugsweise in Form von Mikrosphärulen vorliegende galenische Matrices |
| JP2001524131A (ja) | 1997-05-09 | 2001-11-27 | セイジ、ファーマスーティカルズ、インク | 安定な経口医薬品剤形 |
| EP1028712B1 (en) | 1997-09-19 | 2005-01-12 | Shire Laboratories Inc. | Solid solution beadlet |
| FR2769839B1 (fr) * | 1997-10-21 | 1999-12-17 | Odette Mercedes Salsarulo | Composition anhydre a base de lactulose |
| FR2779962B1 (fr) * | 1998-06-17 | 2002-12-06 | Karim Ioualalen | Composition cosmetique ou dermopharmaceutique sous forme de perles et procedes pour la preparation |
| WO2000067728A2 (de) | 1999-05-07 | 2000-11-16 | Pharmasol Gmbh | Lipidpartikel auf der basis von mischungen von flüssigen und festen lipiden und verfahren zu ihrer herstellung |
| RU2246293C2 (ru) | 1999-06-14 | 2005-02-20 | Космо С.П.А. | Фармацевтические композиции для перорального введения с регулируемым высвобождением активного ингредиента и маскируемым вкусом |
| ITMI991316A1 (it) | 1999-06-14 | 2000-12-14 | Cip Ninety Two 92 S A | Composizioni farmaceutiche orali a rilascio modificato di mesalazina |
| DE60133706T2 (de) * | 2000-10-10 | 2009-07-02 | Wyeth Holdings Corp. | Stabilisierte Arzneizusammensetzungen zur parenteralen Vearbreichung |
| JP3597823B2 (ja) | 2002-02-07 | 2004-12-08 | 沢井製薬株式会社 | 固形製剤 |
| FR2852843B1 (fr) | 2003-03-24 | 2008-05-23 | Karim Ioualalen | Systeme galenique permettant le masquage du gout |
-
2003
- 2003-03-24 FR FR0303568A patent/FR2852843B1/fr not_active Expired - Lifetime
-
2004
- 2004-03-24 US US10/550,027 patent/US20070116728A1/en not_active Abandoned
- 2004-03-24 JP JP2006505750A patent/JP5072355B2/ja not_active Expired - Fee Related
- 2004-03-24 WO PCT/FR2004/000729 patent/WO2004084856A2/fr not_active Ceased
- 2004-03-24 EP EP04742337.1A patent/EP1605918B1/fr not_active Expired - Lifetime
- 2004-03-24 AU AU2004224601A patent/AU2004224601A1/en not_active Abandoned
- 2004-03-24 MX MXPA05010217A patent/MXPA05010217A/es active IP Right Grant
- 2004-03-24 NZ NZ542590A patent/NZ542590A/en unknown
- 2004-03-24 CA CA2519962A patent/CA2519962C/fr not_active Expired - Fee Related
- 2004-03-24 KR KR1020057017992A patent/KR20060012576A/ko not_active Ceased
-
2010
- 2010-04-26 US US12/767,248 patent/US8911788B2/en not_active Expired - Lifetime
-
2014
- 2014-10-27 US US14/523,999 patent/US9192679B2/en not_active Expired - Fee Related
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