KR20060012576A - 활성 성분의 전달을 위한 신규한 갈레누스 시스템, 제조방법 및 용도 - Google Patents

활성 성분의 전달을 위한 신규한 갈레누스 시스템, 제조방법 및 용도 Download PDF

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Publication number
KR20060012576A
KR20060012576A KR1020057017992A KR20057017992A KR20060012576A KR 20060012576 A KR20060012576 A KR 20060012576A KR 1020057017992 A KR1020057017992 A KR 1020057017992A KR 20057017992 A KR20057017992 A KR 20057017992A KR 20060012576 A KR20060012576 A KR 20060012576A
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KR
South Korea
Prior art keywords
galenus
wax
active ingredient
particles
composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
KR1020057017992A
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English (en)
Korean (ko)
Inventor
카랭 유알라랑
로즈 안느 래이날
Original Assignee
오랄랑스 파르마
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
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Application filed by 오랄랑스 파르마 filed Critical 오랄랑스 파르마
Publication of KR20060012576A publication Critical patent/KR20060012576A/ko
Ceased legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/65Tetracyclines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12Carboxylic acids; Salts or anhydrides thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1617Organic compounds, e.g. phospholipids, fats
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00Anaesthetics
    • A61P23/02Local anaesthetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pain & Pain Management (AREA)
  • Biophysics (AREA)
  • Anesthesiology (AREA)
  • Diabetes (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
KR1020057017992A 2003-03-24 2004-03-24 활성 성분의 전달을 위한 신규한 갈레누스 시스템, 제조방법 및 용도 Ceased KR20060012576A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0303568A FR2852843B1 (fr) 2003-03-24 2003-03-24 Systeme galenique permettant le masquage du gout
FR03/03568 2003-03-24

Publications (1)

Publication Number Publication Date
KR20060012576A true KR20060012576A (ko) 2006-02-08

Family

ID=32947122

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020057017992A Ceased KR20060012576A (ko) 2003-03-24 2004-03-24 활성 성분의 전달을 위한 신규한 갈레누스 시스템, 제조방법 및 용도

Country Status (10)

Country Link
US (3) US20070116728A1 (enExample)
EP (1) EP1605918B1 (enExample)
JP (1) JP5072355B2 (enExample)
KR (1) KR20060012576A (enExample)
AU (1) AU2004224601A1 (enExample)
CA (1) CA2519962C (enExample)
FR (1) FR2852843B1 (enExample)
MX (1) MXPA05010217A (enExample)
NZ (1) NZ542590A (enExample)
WO (1) WO2004084856A2 (enExample)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2852843B1 (fr) * 2003-03-24 2008-05-23 Karim Ioualalen Systeme galenique permettant le masquage du gout
FR2879930B1 (fr) * 2004-12-23 2007-08-31 Oralance Pharma Sa Nouveau systeme galenique pour le transport d'actif, procede de preparation et utilisation
FR2913884A1 (fr) * 2007-03-21 2008-09-26 Oralance Pharma Sa Systeme galenique hydrophobe non ionisable
US8613956B2 (en) * 2008-06-23 2013-12-24 International Flora Technologies, Ltd. Cosmetic particles that transform from hard to soft particles comprising hydrogenated long-chain triglyceride oils
FR2935270A1 (fr) * 2008-08-28 2010-03-05 Oralance Pharma Composition pharmaceutique de temozolomide pour usage pediatrique
JP6305414B2 (ja) * 2012-10-18 2018-04-04 ディーエスエム アイピー アセッツ ビー.ブイ. カロテノイドを含むビードレット
US20160000714A1 (en) * 2013-03-06 2016-01-07 Capsugel Belgium Nv Curcumin solid lipid particles and methods for their preparation and use
EP3766480A1 (en) 2014-06-10 2021-01-20 Capsugel Belgium NV Orally disintegrating tablet containing solid lipid particles and methods for their preparation and use
WO2016087261A1 (en) 2014-12-04 2016-06-09 Capsugel Belgium N.V. Lipid multiparticulate formulations
US9744221B2 (en) 2014-12-23 2017-08-29 Synthetic Biologics, Inc. Method and compositions for inhibiting or preventing adverse effects of oral antibiotics
FR3059903B1 (fr) * 2016-12-08 2019-03-22 Salsarulo Pharma Medicament oral comprenant un laxatif osmotique incorpore dans une matrice a base de matieres grasses vegetales
UA122741C2 (uk) * 2016-12-08 2020-12-28 Сальсарюло Фарма Пероральний лікарський препарат, що включає осмотичне проносне, поміщене в матрицю на основі рослинних жирів
US10639607B2 (en) 2017-06-16 2020-05-05 Matralix Pte Ltd Systems and methods for preparing wax and lipid particles
CA3072032A1 (en) 2017-08-07 2019-02-14 Finch Therapeutics, Inc. Compositions and methods for maintaining and restoring a healthy gut barrier
EP3737750B1 (en) 2018-01-09 2024-06-05 Theriva Biologics, Inc. Alkaline phosphatase agents for treatment of neurodevelopmental disorders
EP3755353A4 (en) 2018-02-23 2022-03-09 Finch Therapeutics Holdings LLC IMMUNOTHERAPIES RELATED TO MICROBIOME
FR3078630B1 (fr) * 2018-03-08 2021-05-14 Karim Ioualalen Mode de formulation sous forme de solide divise hydrophobe
WO2019183209A1 (en) 2018-03-20 2019-09-26 Synthetic Biologics, Inc. Alkaline phosphatase agents for treatment of radiation disorders
US11638699B2 (en) 2018-03-20 2023-05-02 Theriva Biologics, Inc. Intestinal alkaline phosphatase formulations
FR3079146B1 (fr) * 2018-03-23 2020-04-17 Karim Ioualalen Formulation gastroprotectrice de complexes d’enzymes permettant de restaurer la fonction digestive.
US20220257726A1 (en) 2019-07-18 2022-08-18 Synthetic Biologics, Inc. Intestinal alkaline phosphatase-based treatments of metabolic disorders
PE20221399A1 (es) 2019-07-19 2022-09-15 Finch Therapeutics Holdings Llc Metodos y productos para el tratamiento de trastornos gastrointestinales
JP2022547330A (ja) 2019-09-13 2022-11-11 フィンチ セラピューティクス ホールディングス エルエルシー 自閉症スペクトラム障害を治療するための組成物および方法
KR20220101637A (ko) 2019-10-18 2022-07-19 핀치 테라퓨틱스 홀딩스 엘엘씨 박테리아 대사산물을 대상체에 전달하기 위한 조성물 및 방법
WO2021097288A1 (en) 2019-11-15 2021-05-20 Finch Therapeutics Holdings Llc Compositions and methods for treating neurodegenerative diseases
WO2021142358A1 (en) 2020-01-10 2021-07-15 Finch Therapeutics Holdings Llc Compositions and methods for treating hepatic encephalopathy (he)
WO2021142347A1 (en) 2020-01-10 2021-07-15 Finch Therapeutics Holdings Llc Compositions and methods for non-alcoholic steatohepatitis (nash)
TW202140049A (zh) 2020-01-10 2021-11-01 美商芬奇治療控股有限責任公司 用於治療b型肝炎(hbv)及d型肝炎(hdv)之組合物及方法
US20230201265A1 (en) 2020-03-31 2023-06-29 Finch Therapeutics Holdings Llc Compositions comprising non-viable fecal microbiota and methods of use thereof
US20240263251A1 (en) 2021-02-19 2024-08-08 Finch Therapeutics Holdings Llc Compositions and methods for providing secondary bile acids to a subject
CN113308045B (zh) * 2021-05-28 2022-03-22 宁波市鑫晟工贸实业有限公司 一种抗老化的塑料盒及其制备方法
IT202100014330A1 (it) * 2021-06-01 2022-12-01 The Ubeauty Com Llc Prodotto per la cura della pelle e procedimento per la sua realizzazione.
EP4475905A1 (en) * 2022-02-11 2024-12-18 Insitu Biologics, Inc. Sustained release cancer therapeutics formulations

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3146167A (en) * 1961-10-05 1964-08-25 Smith Kline French Lab Method of preparing sustained release pellets and products thereof
US4132753A (en) * 1965-02-12 1979-01-02 American Cyanamid Company Process for preparing oral sustained release granules
GB1323161A (en) * 1970-02-16 1973-07-11 Wyeth John & Brother Ltd Penicillin composition
US4132375A (en) * 1976-01-21 1979-01-02 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Vortex-lift roll-control device
US4590062A (en) * 1984-04-16 1986-05-20 Tech Trade Corp. Dry direct compression compositions for controlled release dosage forms
JPS63301815A (ja) * 1987-01-29 1988-12-08 Taisho Pharmaceut Co Ltd 経口製剤の製造方法
JP2700662B2 (ja) * 1988-06-22 1998-01-21 大正製薬株式会社 被覆製剤
JPH02200639A (ja) * 1989-01-31 1990-08-08 Shinfusou Seiyaku Kk 脂質被覆細菌製剤
IT1229856B (it) 1989-04-20 1991-09-13 Recordati Chem Pharm Compresse a rilascio controllato contenenti flavossato.
US5213810A (en) 1990-03-30 1993-05-25 American Cyanamid Company Stable compositions for parenteral administration and method of making same
EP0525307B1 (en) 1991-07-23 1996-03-06 American Cyanamid Company Stable compositions for parenteral administration and their use
DE4131562A1 (de) 1991-09-18 1993-03-25 Medac Klinische Spezialpraep Arzneistofftraeger aus festen lipidteilchen-feste lipidnanosphaeren (sln)
CA2150119C (en) * 1992-11-30 2005-03-15 Robert C. Cuca Tastemasked pharmaceutical materials
CA2091152C (en) 1993-03-05 2005-05-03 Kirsten Westesen Solid lipid particles, particles of bioactive agents and methods for the manfuacture and use thereof
DE4308282C2 (de) 1993-03-16 1994-12-22 Beiersdorf Ag Vorzugsweise in Form von Mikrosphärulen vorliegende galenische Matrices
AU7375598A (en) 1997-05-09 1998-11-27 Sage Pharmaceuticals, Inc. Stable oral pharmaceutical dosage forms
US6692767B2 (en) 1997-09-19 2004-02-17 Shire Laboratories Inc. Solid solution beadlet
FR2769839B1 (fr) * 1997-10-21 1999-12-17 Odette Mercedes Salsarulo Composition anhydre a base de lactulose
FR2779962B1 (fr) * 1998-06-17 2002-12-06 Karim Ioualalen Composition cosmetique ou dermopharmaceutique sous forme de perles et procedes pour la preparation
AU4917900A (en) 1999-05-07 2000-11-21 Pharmasol Gmbh Lipid particles on the basis of mixtures of liquid and solid lipids and method for producing same
ITMI991316A1 (it) 1999-06-14 2000-12-14 Cip Ninety Two 92 S A Composizioni farmaceutiche orali a rilascio modificato di mesalazina
WO2000076478A1 (en) 1999-06-14 2000-12-21 Cosmo S.P.A. Controlled release and taste masking oral pharmaceutical compositions
DK1197207T3 (da) * 2000-10-10 2008-08-04 Wyeth Corp Stabile sammensætninger til parenteral indgivelse
JP3597823B2 (ja) 2002-02-07 2004-12-08 沢井製薬株式会社 固形製剤
FR2852843B1 (fr) 2003-03-24 2008-05-23 Karim Ioualalen Systeme galenique permettant le masquage du gout

Also Published As

Publication number Publication date
FR2852843B1 (fr) 2008-05-23
NZ542590A (en) 2009-02-28
US8911788B2 (en) 2014-12-16
JP5072355B2 (ja) 2012-11-14
WO2004084856A3 (fr) 2004-11-25
EP1605918A2 (fr) 2005-12-21
US9192679B2 (en) 2015-11-24
MXPA05010217A (es) 2006-03-28
CA2519962A1 (fr) 2004-10-07
US20150044297A1 (en) 2015-02-12
US20070116728A1 (en) 2007-05-24
FR2852843A1 (fr) 2004-10-01
JP2006521334A (ja) 2006-09-21
EP1605918B1 (fr) 2016-09-28
WO2004084856A2 (fr) 2004-10-07
AU2004224601A1 (en) 2004-10-07
US20100221298A1 (en) 2010-09-02
CA2519962C (fr) 2015-03-10

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