JP2006520818A - ポリエチレングリコール結合ｇｌｐ−１化合物 - Google Patents
ポリエチレングリコール結合ｇｌｐ−１化合物 Download PDFInfo
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Classifications
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/605—Glucagons
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
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- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
- A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
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- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
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- Life Sciences & Earth Sciences (AREA)
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- Urology & Nephrology (AREA)
- Child & Adolescent Psychology (AREA)
- Nutrition Science (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US45608103P | 2003-03-19 | 2003-03-19 | |
| PCT/US2004/006082 WO2004093823A2 (en) | 2003-03-19 | 2004-03-19 | Polyethelene glycol link glp-1 compounds |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2006520818A true JP2006520818A (ja) | 2006-09-14 |
| JP2006520818A5 JP2006520818A5 (https=) | 2010-09-24 |
Family
ID=33310655
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006508916A Pending JP2006520818A (ja) | 2003-03-19 | 2004-03-19 | ポリエチレングリコール結合ｇｌｐ−１化合物 |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US7557183B2 (https=) |
| EP (1) | EP1605897B1 (https=) |
| JP (1) | JP2006520818A (https=) |
| KR (1) | KR100733940B1 (https=) |
| CN (1) | CN1832959A (https=) |
| AU (1) | AU2004231461B2 (https=) |
| BR (1) | BRPI0407936A (https=) |
| CA (1) | CA2518336A1 (https=) |
| CO (1) | CO5611157A2 (https=) |
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- 2004-03-19 SI SI200431937T patent/SI1605897T1/sl unknown
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- 2004-03-19 BR BRPI0407936-1A patent/BRPI0407936A/pt not_active IP Right Cessation
- 2004-03-19 NZ NZ541534A patent/NZ541534A/en not_active IP Right Cessation
- 2004-03-19 CA CA002518336A patent/CA2518336A1/en not_active Abandoned
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- 2004-03-19 KR KR1020057017465A patent/KR100733940B1/ko not_active Expired - Fee Related
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| JP2010509248A (ja) * | 2006-11-14 | 2010-03-25 | 上海▲ふぁ▼▲い▼生物技▲しゅぅ▼有限公司 | Ｐｅｇ修飾エキセンジンまたはエキセンジン類似体およびそれらの組成物および使用 |
| US7985731B2 (en) | 2007-06-19 | 2011-07-26 | Otsuka Chemical Holdings Co., Ltd. | Sugar chain added GLP-1 peptide |
| US8507429B2 (en) | 2007-06-19 | 2013-08-13 | Glytech, Inc. | Sugar chain added GLP-1 peptide |
| JP2010538042A (ja) * | 2007-09-05 | 2010-12-09 | ノボ・ノルデイスク・エー／エス | グルカゴン様ペプチド−１誘導体及びそれらの医薬用途 |
| US8895694B2 (en) | 2007-09-05 | 2014-11-25 | Novo Nordisk A/S | Glucagon-Like Peptide-1 derivatives and their pharmaceutical use |
| US9067977B2 (en) | 2007-09-05 | 2015-06-30 | Novo Nordisk A/S | Peptides derivatized with A-B-C-D- and their therapeutical use |
| US9409966B2 (en) | 2007-09-05 | 2016-08-09 | Novo Nordisk A/S | Glucagon-like peptide-1 derivatives and their pharmaceutical use |
| US9657079B2 (en) | 2007-09-05 | 2017-05-23 | Novo Nordisk A/S | Truncated GLP-1 derivatives and their therapeutical use |
| WO2011052523A1 (ja) | 2009-10-30 | 2011-05-05 | 大塚化学株式会社 | 抗原性ｇｌｐ－１アナログの糖鎖付加体 |
| JP2013527178A (ja) * | 2010-05-17 | 2013-06-27 | ゼジャン・ベータ・ファーマ・インコーポレーテッド | 新規のグルカゴン様ペプチド類似体、組成物、および使用方法 |
| JP2013537879A (ja) * | 2010-09-09 | 2013-10-07 | インスティテュート オブ ファーマコロジー アンド トキシコロジー アカデミー オブ ミリタリー メディカル サイエンシス ピーエルエイ チャイナ | 部位特異的ｐｅｇ修飾エキセンディン−４アナログ及びその使用 |
| US10960052B2 (en) | 2010-12-16 | 2021-03-30 | Novo Nordisk A/S | Solid compositions comprising a GLP-1 agonist and a salt of N-(8-(2-hydroxybenzoyl) amino) caprylic acid |
| US11382957B2 (en) | 2010-12-16 | 2022-07-12 | Novo Nordisk A/S | Solid compositions comprising a GLP-1 agonist and a salt of N-(8-(2-hydroxybenzoyl)amino)caprylic acid |
| US11034746B2 (en) | 2011-04-12 | 2021-06-15 | Novo Nordisk A/S | Double-acylated GLP-1 derivatives |
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| US11759502B2 (en) | 2012-03-22 | 2023-09-19 | Novo Nordisk A/S | Compositions of GLP-1 peptides and preparation thereof |
| US10933120B2 (en) | 2012-03-22 | 2021-03-02 | Novo Nordisk A/S | Compositions of GLP-1 peptides and preparation thereof |
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| US11759501B2 (en) | 2012-03-22 | 2023-09-19 | Novo Nordisk A/S | Compositions of GLP-1 peptides and preparation thereof |
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| US11759503B2 (en) | 2012-03-22 | 2023-09-19 | Novo Nordisk A/S | Compositions of GLP-1 peptides and preparation thereof |
| US11033499B2 (en) | 2012-06-20 | 2021-06-15 | Novo Nordisk A/S | Tablet formulation comprising a GLP-1 peptide and a delivery agent |
| US12239739B2 (en) | 2013-05-02 | 2025-03-04 | Novo Nordisk A/S | Oral dosing of GLP-1 compounds |
| US12514822B2 (en) | 2013-05-02 | 2026-01-06 | Novo Nordisk A/S | Oral dosing of GLP-1 compounds |
| US10702611B2 (en) | 2014-12-02 | 2020-07-07 | Rezolute, Inc. | Use of hydrophobic organic acids to increase hydrophobicity of proteins and protein conjugates |
| JP2017536387A (ja) * | 2014-12-02 | 2017-12-07 | アントリアバイオ インコーポレイテッドＡｎｔｒｉａｂｉｏ，Ｉｎｃ． | 疎水性が高められたタンパク質及びタンパク質コンジュゲート |
| US11833248B2 (en) | 2018-02-02 | 2023-12-05 | Novo Nordisk A/S | Solid compositions comprising a GLP-1 agonist and a salt of N-(8-(2-hydroxybenzoyl)amino)caprylic acid |
| US12396953B2 (en) | 2018-02-02 | 2025-08-26 | Novo Nordisk A/S | Solid compositions comprising a GLP-1 agonist and a salt of N-(8-(2-hydroxybenzoyl)amino)caprylic acid |
Also Published As
| Publication number | Publication date |
|---|---|
| ECSP056025A (es) | 2006-01-27 |
| CA2518336A1 (en) | 2004-11-04 |
| CY1114035T1 (el) | 2016-07-27 |
| BRPI0407936A (pt) | 2006-02-21 |
| NO20054310L (no) | 2005-11-16 |
| MXPA05009940A (es) | 2005-12-05 |
| HRP20050683A2 (en) | 2006-07-31 |
| EA200501482A1 (ru) | 2006-06-30 |
| CO5611157A2 (es) | 2006-02-28 |
| KR20050111386A (ko) | 2005-11-24 |
| UA92451C2 (en) | 2010-11-10 |
| EA009366B1 (ru) | 2007-12-28 |
| AU2004231461A1 (en) | 2004-11-04 |
| NO20054310D0 (no) | 2005-09-19 |
| SI1605897T1 (sl) | 2012-11-30 |
| PL1605897T3 (pl) | 2012-12-31 |
| ES2390270T3 (es) | 2012-11-08 |
| EP1605897A2 (en) | 2005-12-21 |
| US20080113905A1 (en) | 2008-05-15 |
| ZA200506881B (en) | 2006-11-29 |
| DK1605897T3 (da) | 2012-08-20 |
| CR7997A (es) | 2008-11-28 |
| AU2004231461B2 (en) | 2009-11-12 |
| PT1605897E (pt) | 2012-09-10 |
| NZ541534A (en) | 2008-05-30 |
| WO2004093823A2 (en) | 2004-11-04 |
| US7557183B2 (en) | 2009-07-07 |
| CN1832959A (zh) | 2006-09-13 |
| WO2004093823A3 (en) | 2005-12-22 |
| KR100733940B1 (ko) | 2007-06-29 |
| EP1605897B1 (en) | 2012-07-25 |
| EP1605897A4 (en) | 2010-08-04 |
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