JP2006515600A5 - - Google Patents

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Publication number
JP2006515600A5
JP2006515600A5 JP2005502458A JP2005502458A JP2006515600A5 JP 2006515600 A5 JP2006515600 A5 JP 2006515600A5 JP 2005502458 A JP2005502458 A JP 2005502458A JP 2005502458 A JP2005502458 A JP 2005502458A JP 2006515600 A5 JP2006515600 A5 JP 2006515600A5
Authority
JP
Japan
Prior art keywords
compound
formula
group
alkyl group
aryl group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2005502458A
Other languages
English (en)
Japanese (ja)
Other versions
JP2006515600A (ja
JP4579821B2 (ja
Filing date
Publication date
Priority claimed from GB0229243A external-priority patent/GB0229243D0/en
Priority claimed from GB0303589A external-priority patent/GB0303589D0/en
Priority claimed from GB0318515A external-priority patent/GB0318515D0/en
Application filed filed Critical
Priority claimed from PCT/GB2003/005359 external-priority patent/WO2004054986A2/en
Publication of JP2006515600A publication Critical patent/JP2006515600A/ja
Publication of JP2006515600A5 publication Critical patent/JP2006515600A5/ja
Application granted granted Critical
Publication of JP4579821B2 publication Critical patent/JP4579821B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

JP2005502458A 2002-12-16 2003-12-09 ピリミジン化合物を製造するための方法 Expired - Fee Related JP4579821B2 (ja)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB0229243A GB0229243D0 (en) 2002-12-16 2002-12-16 Compounds and process
GB0303589A GB0303589D0 (en) 2003-02-17 2003-02-17 Compounds and process
GB0318515A GB0318515D0 (en) 2003-08-07 2003-08-07 Compounds and process
PCT/GB2003/005359 WO2004054986A2 (en) 2002-12-16 2003-12-09 Process for the preparation of pyrimidine compounds

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2010142779A Division JP5318037B2 (ja) 2002-12-16 2010-06-23 ピリミジン化合物を製造するための方法

Publications (3)

Publication Number Publication Date
JP2006515600A JP2006515600A (ja) 2006-06-01
JP2006515600A5 true JP2006515600A5 (enExample) 2007-02-01
JP4579821B2 JP4579821B2 (ja) 2010-11-10

Family

ID=32600665

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2005502458A Expired - Fee Related JP4579821B2 (ja) 2002-12-16 2003-12-09 ピリミジン化合物を製造するための方法
JP2010142779A Expired - Fee Related JP5318037B2 (ja) 2002-12-16 2010-06-23 ピリミジン化合物を製造するための方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2010142779A Expired - Fee Related JP5318037B2 (ja) 2002-12-16 2010-06-23 ピリミジン化合物を製造するための方法

Country Status (22)

Country Link
US (2) US7524955B2 (enExample)
EP (2) EP1578731B1 (enExample)
JP (2) JP4579821B2 (enExample)
KR (1) KR101060215B1 (enExample)
AR (1) AR042355A1 (enExample)
AT (1) ATE448209T1 (enExample)
AU (1) AU2003288443B2 (enExample)
BR (1) BR0317313A (enExample)
CA (1) CA2509344C (enExample)
CY (1) CY1110605T1 (enExample)
DE (1) DE60330050D1 (enExample)
DK (1) DK1578731T3 (enExample)
ES (1) ES2335279T3 (enExample)
IL (1) IL168884A (enExample)
MX (1) MXPA05006425A (enExample)
MY (1) MY138051A (enExample)
NO (2) NO330983B1 (enExample)
NZ (1) NZ540722A (enExample)
PT (1) PT1578731E (enExample)
SI (1) SI1578731T1 (enExample)
TW (1) TWI322145B (enExample)
WO (1) WO2004054986A2 (enExample)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0011120D0 (en) * 2000-05-09 2000-06-28 Avecia Ltd Process
NL1015744C2 (nl) 2000-07-19 2002-01-22 Dsm Nv Werkwijze voor de bereiding van 2-(6-gesubstitueerde-1,3-dioxan-4-yl) azijnzuurderivaten.
IL159741A0 (en) * 2001-07-13 2004-06-20 Astrazeneca Uk Ltd Preparation of aminopyrimidine compounds
EP1323717A1 (en) 2001-12-27 2003-07-02 Dsm N.V. Process for the preparation of 2-(6-Substituted-1,3-Dioxane-4-yL) acetic acid derivatives
KR20030092446A (ko) * 2002-05-29 2003-12-06 주식회사 한국토종약초연구소 씨형 간염 활성 억제를 갖는 조릿대 추출물을 포함하는조성물
EP1375493A1 (en) 2002-06-17 2004-01-02 Dsm N.V. Process for the preparation of an dioxane acetic acid ester
GB0218781D0 (en) 2002-08-13 2002-09-18 Astrazeneca Ab Chemical process
BR0317313A (pt) 2002-12-16 2005-11-08 Astrazeneca Uk Ltd Processo para a preparação de um composto, e, composto
GB0312896D0 (en) * 2003-06-05 2003-07-09 Astrazeneca Ab Chemical process
UY28501A1 (es) * 2003-09-10 2005-04-29 Astrazeneca Uk Ltd Compuestos químicos
GB0324791D0 (en) 2003-10-24 2003-11-26 Astrazeneca Ab Chemical process
GB0428328D0 (en) * 2004-12-24 2005-02-02 Astrazeneca Uk Ltd Chemical process
GB0514078D0 (en) * 2005-07-08 2005-08-17 Astrazeneca Uk Ltd Chemical process
US8153791B2 (en) 2005-12-21 2012-04-10 Janssen Pharmaceutica N.V. Substituted pyrimidinyl oxime kinase inhibitors
US8013153B2 (en) * 2006-03-23 2011-09-06 Janssen Pharmaceutica, N.V. Substituted pyrimidine kinase inhibitors
TW200831469A (en) * 2006-12-01 2008-08-01 Astrazeneca Uk Ltd Chemical process
WO2011146822A1 (en) 2010-05-21 2011-11-24 Cooper Technologies Company Adapter for bushing latch

Family Cites Families (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3278001A (en) * 1965-02-02 1966-10-11 Charles C Andrews Bearing assembly for auger conveyors
US4698340A (en) * 1984-07-19 1987-10-06 Fujisawa Pharmaceutical Co., Ltd. Pyrimidine derivatives, processes for preparation thereof and composition containing the same
US4689414A (en) * 1986-02-24 1987-08-25 E. R. Squibb & Sons, Inc. 2-(substituted imino)-6-aryl-3,6-dihydro-4-substituted-1,5(2H)-pyrimidinecarboxylic acids and analogs
JPH03501613A (ja) * 1988-10-06 1991-04-11 サンド・アクチエンゲゼルシヤフト ピリミジニル置換ヒドロキシ酸、ラクトン及びエステル並びにそれらを含む製薬学的組成物
FR2665159B1 (fr) 1990-07-24 1992-11-13 Rhone Poulenc Sante Nouveaux derives de la pyridine et de la quinoleine, leur preparation et les compositions pharmaceutiques qui les contiennent.
JP2648897B2 (ja) * 1991-07-01 1997-09-03 塩野義製薬株式会社 ピリミジン誘導体
WO1993008823A1 (en) 1991-11-06 1993-05-13 Tanabe Seiyaku Co., Ltd. Guanidinyl and related cell adhesion modulation compounds
JP3197971B2 (ja) * 1993-03-01 2001-08-13 塩野義製薬株式会社 5−カルボアルコキシピリミジン誘導体の合成方法
US5593992A (en) * 1993-07-16 1997-01-14 Smithkline Beecham Corporation Compounds
NZ264063A (en) * 1993-08-13 1995-11-27 Nihon Nohyaku Co Ltd N-(2-phenylpyrid-3-yl)- and n-(4-phenylpyrimidin-5-yl)-n'-phenylurea derivatives and pharmaceutical compositions
NZ297278A (en) 1994-11-16 1999-06-29 Synaptic Pharma Corp 4-aryl dihydropyrimidine derivatives end medicaments
DE19517186A1 (de) 1995-05-11 1996-11-14 Bayer Ag Verfahren zur Herstellung substituierter 2-Fluor-pyrimidine
US6278001B1 (en) 1995-11-28 2001-08-21 L'oréal Method for preparing (+) compactin and (+) mevinolin analog compounds having a β-hydroxy-δ-lactone grouping
FR2741620B1 (fr) 1995-11-28 1997-12-26 Oreal Procede de preparation de composes a groupement beta-hydroxy -delta-lactone analogues de la (+) compactine et de la (+) mevinoline
WO1997021687A1 (en) 1995-12-14 1997-06-19 Merck & Co., Inc. Process for making dihydropyrimidinones
US5958934A (en) * 1996-05-23 1999-09-28 Syntex (U.S.A.) Inc. Aryl pyrimidine derivatives and uses thereof
SE9702563D0 (sv) * 1997-07-02 1997-07-02 Astra Ab Compounds
EP1003734A2 (en) 1997-08-05 2000-05-31 Merck & Co., Inc. ALPHA 1a ADRENERGIC RECEPTOR ANTAGONIST
GB9903472D0 (en) 1999-02-17 1999-04-07 Zeneca Ltd Chemical process
EP1193259A4 (en) * 1999-06-23 2003-01-29 Ajinomoto Kk dihydropyrimidine
PL211797B1 (pl) 1999-07-13 2012-06-29 Lonza Ag Sposób wytwarzania 2-amino-4-(4-fluorofenylo)-6-alkilopirymidyno-5-karboksylanu oraz nowe związki pośrednie i sposoby ich wytwarzania
GB0003305D0 (en) 2000-02-15 2000-04-05 Zeneca Ltd Pyrimidine derivatives
WO2001072706A1 (en) 2000-03-28 2001-10-04 Biocon India Limited Synthesis of [r-(r*,r*)]-2-(4-fluorophenyl)-beta,delta-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1h-pyrrole-1-heptanoic acid hemi calcium salt (atorvastatin)
GB0011120D0 (en) 2000-05-09 2000-06-28 Avecia Ltd Process
GB0011163D0 (en) 2000-05-10 2000-06-28 Astrazeneca Ab Chemical compound
NL1015744C2 (nl) 2000-07-19 2002-01-22 Dsm Nv Werkwijze voor de bereiding van 2-(6-gesubstitueerde-1,3-dioxan-4-yl) azijnzuurderivaten.
IL159741A0 (en) 2001-07-13 2004-06-20 Astrazeneca Uk Ltd Preparation of aminopyrimidine compounds
EP1323717A1 (en) 2001-12-27 2003-07-02 Dsm N.V. Process for the preparation of 2-(6-Substituted-1,3-Dioxane-4-yL) acetic acid derivatives
KR100511533B1 (ko) 2002-04-09 2005-08-31 임광민 키랄 중간체, 그의 제조방법 및 그를 이용한 HMG-CoA환원저해제의 제조방법
EP1375493A1 (en) 2002-06-17 2004-01-02 Dsm N.V. Process for the preparation of an dioxane acetic acid ester
GB0218781D0 (en) 2002-08-13 2002-09-18 Astrazeneca Ab Chemical process
BR0317313A (pt) 2002-12-16 2005-11-08 Astrazeneca Uk Ltd Processo para a preparação de um composto, e, composto
WO2004103977A2 (en) 2003-05-21 2004-12-02 Ciba Specialty Chemicals Holding Inc. Process for the preparation of pyrimidine derivatives
GB0312896D0 (en) 2003-06-05 2003-07-09 Astrazeneca Ab Chemical process
UY28501A1 (es) 2003-09-10 2005-04-29 Astrazeneca Uk Ltd Compuestos químicos
GB0321827D0 (en) 2003-09-18 2003-10-15 Astrazeneca Uk Ltd Chemical compounds
GB0324791D0 (en) 2003-10-24 2003-11-26 Astrazeneca Ab Chemical process
WO2005063728A2 (en) 2003-12-24 2005-07-14 Teva Pharmaceutical Industries Ltd. Process for preparation of statins with high syn to anti ratio
GB0428328D0 (en) 2004-12-24 2005-02-02 Astrazeneca Uk Ltd Chemical process

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