BR0317313A - Processo para a preparação de um composto, e, composto - Google Patents

Processo para a preparação de um composto, e, composto

Info

Publication number
BR0317313A
BR0317313A BR0317313-5A BR0317313A BR0317313A BR 0317313 A BR0317313 A BR 0317313A BR 0317313 A BR0317313 A BR 0317313A BR 0317313 A BR0317313 A BR 0317313A
Authority
BR
Brazil
Prior art keywords
compound
formula
alkyl
group
preparation
Prior art date
Application number
BR0317313-5A
Other languages
English (en)
Portuguese (pt)
Inventor
Lee Newton
Mark Bailey
Original Assignee
Astrazeneca Uk Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0229243A external-priority patent/GB0229243D0/en
Priority claimed from GB0303589A external-priority patent/GB0303589D0/en
Priority claimed from GB0318515A external-priority patent/GB0318515D0/en
Application filed by Astrazeneca Uk Ltd filed Critical Astrazeneca Uk Ltd
Publication of BR0317313A publication Critical patent/BR0317313A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/20—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D239/22—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/67—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of saturated acids
    • C07C69/716—Esters of keto-carboxylic acids or aldehydo-carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/42—One nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Catalysts (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Indole Compounds (AREA)
BR0317313-5A 2002-12-16 2003-12-09 Processo para a preparação de um composto, e, composto BR0317313A (pt)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB0229243A GB0229243D0 (en) 2002-12-16 2002-12-16 Compounds and process
GB0303589A GB0303589D0 (en) 2003-02-17 2003-02-17 Compounds and process
GB0318515A GB0318515D0 (en) 2003-08-07 2003-08-07 Compounds and process
PCT/GB2003/005359 WO2004054986A2 (en) 2002-12-16 2003-12-09 Process for the preparation of pyrimidine compounds

Publications (1)

Publication Number Publication Date
BR0317313A true BR0317313A (pt) 2005-11-08

Family

ID=32600665

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0317313-5A BR0317313A (pt) 2002-12-16 2003-12-09 Processo para a preparação de um composto, e, composto

Country Status (22)

Country Link
US (2) US7524955B2 (enExample)
EP (2) EP1578731B1 (enExample)
JP (2) JP4579821B2 (enExample)
KR (1) KR101060215B1 (enExample)
AR (1) AR042355A1 (enExample)
AT (1) ATE448209T1 (enExample)
AU (1) AU2003288443B2 (enExample)
BR (1) BR0317313A (enExample)
CA (1) CA2509344C (enExample)
CY (1) CY1110605T1 (enExample)
DE (1) DE60330050D1 (enExample)
DK (1) DK1578731T3 (enExample)
ES (1) ES2335279T3 (enExample)
IL (1) IL168884A (enExample)
MX (1) MXPA05006425A (enExample)
MY (1) MY138051A (enExample)
NO (2) NO330983B1 (enExample)
NZ (1) NZ540722A (enExample)
PT (1) PT1578731E (enExample)
SI (1) SI1578731T1 (enExample)
TW (1) TWI322145B (enExample)
WO (1) WO2004054986A2 (enExample)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0011120D0 (en) 2000-05-09 2000-06-28 Avecia Ltd Process
NL1015744C2 (nl) 2000-07-19 2002-01-22 Dsm Nv Werkwijze voor de bereiding van 2-(6-gesubstitueerde-1,3-dioxan-4-yl) azijnzuurderivaten.
CN1301977C (zh) * 2001-07-13 2007-02-28 阿斯特拉曾尼卡英国有限公司 氨基嘧啶化合物的制备方法
EP1323717A1 (en) 2001-12-27 2003-07-02 Dsm N.V. Process for the preparation of 2-(6-Substituted-1,3-Dioxane-4-yL) acetic acid derivatives
KR20030092446A (ko) * 2002-05-29 2003-12-06 주식회사 한국토종약초연구소 씨형 간염 활성 억제를 갖는 조릿대 추출물을 포함하는조성물
EP1375493A1 (en) 2002-06-17 2004-01-02 Dsm N.V. Process for the preparation of an dioxane acetic acid ester
GB0218781D0 (en) 2002-08-13 2002-09-18 Astrazeneca Ab Chemical process
JP4579821B2 (ja) 2002-12-16 2010-11-10 アストラゼネカ・ユーケイ・リミテッド ピリミジン化合物を製造するための方法
GB0312896D0 (en) * 2003-06-05 2003-07-09 Astrazeneca Ab Chemical process
UY28501A1 (es) 2003-09-10 2005-04-29 Astrazeneca Uk Ltd Compuestos químicos
GB0324791D0 (en) * 2003-10-24 2003-11-26 Astrazeneca Ab Chemical process
GB0428328D0 (en) * 2004-12-24 2005-02-02 Astrazeneca Uk Ltd Chemical process
GB0514078D0 (en) * 2005-07-08 2005-08-17 Astrazeneca Uk Ltd Chemical process
US8153791B2 (en) 2005-12-21 2012-04-10 Janssen Pharmaceutica N.V. Substituted pyrimidinyl oxime kinase inhibitors
WO2007109783A2 (en) * 2006-03-23 2007-09-27 Janssen Pharmaceutica, N.V. Substituted pyrimidine kinase inhibitors
TW200831469A (en) * 2006-12-01 2008-08-01 Astrazeneca Uk Ltd Chemical process
US8328569B2 (en) 2010-05-21 2012-12-11 Cooper Technologies Company Adapter for coupling a deadbreak bushing to a deadbreak arrestor elbow

Family Cites Families (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3278001A (en) * 1965-02-02 1966-10-11 Charles C Andrews Bearing assembly for auger conveyors
US4698340A (en) 1984-07-19 1987-10-06 Fujisawa Pharmaceutical Co., Ltd. Pyrimidine derivatives, processes for preparation thereof and composition containing the same
US4689414A (en) * 1986-02-24 1987-08-25 E. R. Squibb & Sons, Inc. 2-(substituted imino)-6-aryl-3,6-dihydro-4-substituted-1,5(2H)-pyrimidinecarboxylic acids and analogs
WO1990003973A1 (en) 1988-10-06 1990-04-19 Sandoz Ag Pyrimidinyl-substituted hydroxyacids, lactones and esters and pharmaceutical compositions containing them
FR2665159B1 (fr) 1990-07-24 1992-11-13 Rhone Poulenc Sante Nouveaux derives de la pyridine et de la quinoleine, leur preparation et les compositions pharmaceutiques qui les contiennent.
JP2648897B2 (ja) * 1991-07-01 1997-09-03 塩野義製薬株式会社 ピリミジン誘導体
WO1993008823A1 (en) 1991-11-06 1993-05-13 Tanabe Seiyaku Co., Ltd. Guanidinyl and related cell adhesion modulation compounds
JP3197971B2 (ja) 1993-03-01 2001-08-13 塩野義製薬株式会社 ５−カルボアルコキシピリミジン誘導体の合成方法
US5593992A (en) * 1993-07-16 1997-01-14 Smithkline Beecham Corporation Compounds
NZ264063A (en) 1993-08-13 1995-11-27 Nihon Nohyaku Co Ltd N-(2-phenylpyrid-3-yl)- and n-(4-phenylpyrimidin-5-yl)-n'-phenylurea derivatives and pharmaceutical compositions
JP3200070B2 (ja) 1994-11-16 2001-08-20 シナプティック・ファーマスーティカル・コーポレーション ジヒドロピリミジン類およびその使用
DE19517186A1 (de) * 1995-05-11 1996-11-14 Bayer Ag Verfahren zur Herstellung substituierter 2-Fluor-pyrimidine
FR2741620B1 (fr) 1995-11-28 1997-12-26 Oreal Procede de preparation de composes a groupement beta-hydroxy -delta-lactone analogues de la (+) compactine et de la (+) mevinoline
US6278001B1 (en) 1995-11-28 2001-08-21 L'oréal Method for preparing (+) compactin and (+) mevinolin analog compounds having a β-hydroxy-δ-lactone grouping
CZ184098A3 (cs) 1995-12-14 1998-11-11 Merck And Co., Inc. Způsob výroby dihydropyrimidinonů
US5958934A (en) 1996-05-23 1999-09-28 Syntex (U.S.A.) Inc. Aryl pyrimidine derivatives and uses thereof
SE9702563D0 (sv) 1997-07-02 1997-07-02 Astra Ab Compounds
AU8680598A (en) 1997-08-05 1999-03-01 Merck & Co., Inc. Alpha 1a adrenergic receptor antagonist
GB9903472D0 (en) * 1999-02-17 1999-04-07 Zeneca Ltd Chemical process
AU5568400A (en) * 1999-06-23 2001-01-09 Ajinomoto Co., Inc. Novel dihydropyrimidine derivatives
AU6266600A (en) 1999-07-13 2001-01-30 Lonza A.G. Process for preparing 2-amino-4-(4-fluorphenyl)-6-alkylpyrimidine-5-carboxylate
GB0003305D0 (en) 2000-02-15 2000-04-05 Zeneca Ltd Pyrimidine derivatives
WO2001072706A1 (en) 2000-03-28 2001-10-04 Biocon India Limited Synthesis of [r-(r*,r*)]-2-(4-fluorophenyl)-beta,delta-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1h-pyrrole-1-heptanoic acid hemi calcium salt (atorvastatin)
GB0011120D0 (en) 2000-05-09 2000-06-28 Avecia Ltd Process
GB0011163D0 (en) 2000-05-10 2000-06-28 Astrazeneca Ab Chemical compound
NL1015744C2 (nl) 2000-07-19 2002-01-22 Dsm Nv Werkwijze voor de bereiding van 2-(6-gesubstitueerde-1,3-dioxan-4-yl) azijnzuurderivaten.
CN1301977C (zh) 2001-07-13 2007-02-28 阿斯特拉曾尼卡英国有限公司 氨基嘧啶化合物的制备方法
EP1323717A1 (en) 2001-12-27 2003-07-02 Dsm N.V. Process for the preparation of 2-(6-Substituted-1,3-Dioxane-4-yL) acetic acid derivatives
KR100511533B1 (ko) 2002-04-09 2005-08-31 임광민 키랄 중간체, 그의 제조방법 및 그를 이용한 HMG-CoA환원저해제의 제조방법
EP1375493A1 (en) 2002-06-17 2004-01-02 Dsm N.V. Process for the preparation of an dioxane acetic acid ester
GB0218781D0 (en) 2002-08-13 2002-09-18 Astrazeneca Ab Chemical process
JP4579821B2 (ja) 2002-12-16 2010-11-10 アストラゼネカ・ユーケイ・リミテッド ピリミジン化合物を製造するための方法
WO2004103977A2 (en) 2003-05-21 2004-12-02 Ciba Specialty Chemicals Holding Inc. Process for the preparation of pyrimidine derivatives
GB0312896D0 (en) 2003-06-05 2003-07-09 Astrazeneca Ab Chemical process
UY28501A1 (es) 2003-09-10 2005-04-29 Astrazeneca Uk Ltd Compuestos químicos
GB0321827D0 (en) 2003-09-18 2003-10-15 Astrazeneca Uk Ltd Chemical compounds
GB0324791D0 (en) 2003-10-24 2003-11-26 Astrazeneca Ab Chemical process
US20050159615A1 (en) 2003-12-24 2005-07-21 Entire Interest. Process for preparation of statins with high syn to anti ratio
GB0428328D0 (en) 2004-12-24 2005-02-02 Astrazeneca Uk Ltd Chemical process

Also Published As

Publication number Publication date
JP4579821B2 (ja) 2010-11-10
NO20110366L (no) 2005-07-07
US7524955B2 (en) 2009-04-28
CY1110605T1 (el) 2015-04-29
SI1578731T1 (sl) 2010-02-26
AR042355A1 (es) 2005-06-15
PT1578731E (pt) 2010-01-12
KR20050085674A (ko) 2005-08-29
AU2003288443A1 (en) 2004-07-09
DK1578731T3 (da) 2010-02-15
NZ540722A (en) 2008-03-28
JP5318037B2 (ja) 2013-10-16
JP2010248222A (ja) 2010-11-04
HK1080477A1 (en) 2006-04-28
EP1578731A2 (en) 2005-09-28
NO330983B1 (no) 2011-08-29
US8273878B2 (en) 2012-09-25
NO20052781L (no) 2005-07-07
ES2335279T3 (es) 2010-03-24
EP2088142A3 (en) 2010-04-21
WO2004054986A2 (en) 2004-07-01
IL168884A (en) 2011-01-31
MY138051A (en) 2009-04-30
US20090264654A1 (en) 2009-10-22
MXPA05006425A (es) 2005-08-19
EP2088142A2 (en) 2009-08-12
WO2004054986A3 (en) 2004-12-02
TW200418809A (en) 2004-10-01
ATE448209T1 (de) 2009-11-15
CA2509344C (en) 2011-10-04
JP2006515600A (ja) 2006-06-01
KR101060215B1 (ko) 2011-08-29
DE60330050D1 (de) 2009-12-24
US20060052604A1 (en) 2006-03-09
EP1578731B1 (en) 2009-11-11
WO2004054986A8 (en) 2005-07-21
TWI322145B (en) 2010-03-21
CA2509344A1 (en) 2004-07-01
AU2003288443B2 (en) 2007-10-25

Similar Documents

Publication Publication Date Title
BR0317313A (pt) Processo para a preparação de um composto, e, composto
HUT44044A (en) Process for preparing place-specific alkylating agents
CA2328780A1 (en) Dihydropyrimidines
TR200102957T2 (tr) Sitalopram hazırlanması için metod.
AR023152A1 (es) Compuesto tienopirimidina, procedimiento para producirlo, composicion farmaceutica que lo comprende y uso de dicho compuesto para preparar dichacomposicion
BR9915158A (pt) Método para preparação de citalopram
ES2195510T3 (es) Derivados de imidazopiridina y procedimiento para prepararlos.
PT88992A (pt) Processo para a preparacao de compostos contendo fosforo uteis como inibidores de colagenase
MY122255A (en) Acrylonitrile compounds, process for their production and pesticides containing them
NZ503912A (en) Piperidinylaminomethyl trifluoromethyl cyclic ether compounds and their use as substance P antagonists
ATE97410T1 (de) 6-amino-6-desoxyfumagillole, ihre herstellung und ihre verwendung.
MY101618A (en) Intermediates for the production of epipodophyloxin and related compounds and processes for the preparation and use thereof
WO2003004459A3 (en) Process for the preparation of nitrile compounds
EP0335979A4 (en) Thienopyrimidine derivatives
FI911189A0 (fi) Nya ureaderivat och deras salter, dessa innehaollande farmaceutiska blandningar och foerfarande foer deras framstaellning.
AR019661A1 (es) Procedimiento para la manufactura de compuestos de piridina-2,3-dicarboxilato y compuesto para su exclusivo uso en dicho procedimiento
NO324252B1 (no) Fremgangsmate for fremstilling av en substituert imidazopyridinforbindelse
DE69815380D1 (de) N,n'-bis (sulfonyl) hydrazine die als antineoplastische mittel nützlich sind
BR0008936A (pt) Derivados de 1,3,4-oxadiazol e processo para produzir os mesmos
ATE258187T1 (de) Herstellung von 2'-substitutierter rns
BRPI0512632A (pt) processo para a preparação de biarildifosfinas assimetricamente substituìdas
ES2190610T3 (es) Sintesis de 3-carbometoxi-4,5-dimetiltiofeno.
BR9812736A (pt) Novo processo para produzir derivados de aminopiperazina
BR0105801B1 (pt) processo para produÇço de derivado alquilamina substituÍdo.
DE69022660D1 (de) Verfahren zur Herstellung von Carbamatderivaten des Lankacidines.

Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 10A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2259 DE 22/04/2014.