BR0008936A - Derivados de 1,3,4-oxadiazol e processo para produzir os mesmos - Google Patents

Derivados de 1,3,4-oxadiazol e processo para produzir os mesmos

Info

Publication number
BR0008936A
BR0008936A BR0008936-2A BR0008936A BR0008936A BR 0008936 A BR0008936 A BR 0008936A BR 0008936 A BR0008936 A BR 0008936A BR 0008936 A BR0008936 A BR 0008936A
Authority
BR
Brazil
Prior art keywords
same
group
oxadiazole derivatives
formula
produce
Prior art date
Application number
BR0008936-2A
Other languages
English (en)
Inventor
Tsutomu Kojima
Katsutoshi Hachiya
Kazuyuki Ohmoto
Original Assignee
Ono Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ono Pharmaceutical Co filed Critical Ono Pharmaceutical Co
Publication of BR0008936A publication Critical patent/BR0008936A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
    • C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
    • C07D271/10—1,3,4-Oxadiazoles; Hydrogenated 1,3,4-oxadiazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06139—Dipeptides with the first amino acid being heterocyclic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0821—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

"DERIVADOS DE 1,3,4-OXADIAZOL E PROCESSO PARA PRODUZIR OS MESMOS". Derivados de oxadiazol representados pela fórmula (I): (em que R^ 1^ representa um átomo de hidrogênio ou um grupo protetor amino; R^ 2^, R^ 3^ e R^ 4^ cada um independentemente representa um grupo alquila, um grupo cicloalquila, um grupo fenila, o qual pode ser substituído, ou um grupo 3,4-metilenodioxifenila, ou R^ 3^ e R^ 4^ são colocados juntos para representarem um grupo alquileno C~ 2-6~), um processo de produzir o mesmo, e um processo para produzir derivados de oxadiazol representados pela fórmula (II): (em que todos símbolos possuem os mesmos significados como descrito acima) usando o derivado acima. De acordo com a invenção, o composto representado pela fórmula (II) é produzido através de menos etapas com alto rendimento.
BR0008936-2A 1999-03-12 2000-03-10 Derivados de 1,3,4-oxadiazol e processo para produzir os mesmos BR0008936A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP6606599 1999-03-12
PCT/JP2000/001464 WO2000055145A1 (fr) 1999-03-12 2000-03-10 Derives de 1,3,4-oxadiazole et leur procede de fabrication

Publications (1)

Publication Number Publication Date
BR0008936A true BR0008936A (pt) 2002-04-09

Family

ID=13305090

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0008936-2A BR0008936A (pt) 1999-03-12 2000-03-10 Derivados de 1,3,4-oxadiazol e processo para produzir os mesmos

Country Status (16)

Country Link
US (2) US6534658B1 (pt)
EP (1) EP1162199A4 (pt)
KR (1) KR20010102569A (pt)
CN (1) CN1350525A (pt)
AU (1) AU2941200A (pt)
BR (1) BR0008936A (pt)
CA (1) CA2367418A1 (pt)
HU (1) HUP0200476A3 (pt)
MX (1) MXPA01009165A (pt)
NO (1) NO20014393L (pt)
NZ (1) NZ513921A (pt)
RU (1) RU2001124908A (pt)
TR (1) TR200102680T2 (pt)
TW (1) TW482763B (pt)
WO (1) WO2000055145A1 (pt)
ZA (1) ZA200107256B (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2002120801A (ru) * 2000-02-03 2004-01-10 Оно Фармасьютикал Ко., Лтд. (Jp) Производные 1,3,4-оксадиазола и способ их получения
JPWO2002014310A1 (ja) * 2000-08-10 2004-01-15 小野薬品工業株式会社 ２−［５−アミノ−６−オキソ−２−フェニル−１，６−ジヒドロ−１−ピリミジル］−Ｎ−［１−（２−［５−ｔ−ブチル−１，３，４−オキサジアゾリル］カルボニル）−２−（Ｒ，Ｓ）−メチルプロピル］アセトアミド・塩酸塩化合物
KR20030027119A (ko) * 2000-09-08 2003-04-03 오노 야꾸힝 고교 가부시키가이샤 1,3,4-옥사디아졸 유도체의 신규 결정, 그 제조 방법 및그것을 유효 성분으로서 함유하는 약제
WO2002051815A1 (fr) * 2000-12-26 2002-07-04 Ono Pharmaceutical Co., Ltd. Derives de pyrimidine et procede de preparation de ceux-ci
JP2007518711A (ja) * 2003-12-19 2007-07-12 メルク　エンド　カムパニー　インコーポレーテッド 有糸分裂キネシン阻害剤
KR20090086802A (ko) 2008-02-11 2009-08-14 삼성전자주식회사 옥사디아졸렌기를 포함하는 디페노퀴논계 화합물을포함하는 전자사진 감광체 및 이를 채용한 전자사진화상형성장치

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5618792A (en) 1994-11-21 1997-04-08 Cortech, Inc. Substituted heterocyclic compounds useful as inhibitors of (serine proteases) human neutrophil elastase
US6015791A (en) * 1994-11-21 2000-01-18 Cortech Inc. Serine protease inhibitors-cycloheptane derivatives
US5591695A (en) * 1995-02-08 1997-01-07 American Cyanamid Co. Herbicidal [1,3,4]oxadiazoles and thiadiazoles
NZ336046A (en) * 1996-12-06 2000-10-27 Cortech Inc Serine protease inhibitors containing substituted oxadiazole, thiadiazole and triazole peptide derivatives

Also Published As

Publication number Publication date
NO20014393D0 (no) 2001-09-10
MXPA01009165A (es) 2002-08-20
TR200102680T2 (tr) 2002-07-22
HUP0200476A3 (en) 2004-03-29
HUP0200476A2 (en) 2002-08-28
WO2000055145A1 (fr) 2000-09-21
CN1350525A (zh) 2002-05-22
NZ513921A (en) 2001-09-28
AU2941200A (en) 2000-10-04
ZA200107256B (en) 2002-12-02
US20030153758A1 (en) 2003-08-14
EP1162199A4 (en) 2002-06-05
KR20010102569A (ko) 2001-11-15
NO20014393L (no) 2001-11-08
RU2001124908A (ru) 2004-02-27
EP1162199A1 (en) 2001-12-12
TW482763B (en) 2002-04-11
US6534658B1 (en) 2003-03-18
CA2367418A1 (en) 2000-09-21

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 5A, 6A E 7A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 1925 DE 27/11/2007.