ATE277015T1 - Verfahren zur herstellung von 1,4-dihydropyridine sowie in diesem verfahren verwendete verbindungen - Google Patents

Verfahren zur herstellung von 1,4-dihydropyridine sowie in diesem verfahren verwendete verbindungen

Info

Publication number
ATE277015T1
ATE277015T1 AT98955389T AT98955389T ATE277015T1 AT E277015 T1 ATE277015 T1 AT E277015T1 AT 98955389 T AT98955389 T AT 98955389T AT 98955389 T AT98955389 T AT 98955389T AT E277015 T1 ATE277015 T1 AT E277015T1
Authority
AT
Austria
Prior art keywords
formula
aralkyl
cycloalkyl
alkyl
iii
Prior art date
Application number
AT98955389T
Other languages
English (en)
Inventor
Gunnar Leo Karup
Herbert Fritz Preikschat
Soren Bols Pedersen
Original Assignee
Gea Farmaceutisk Fabrik As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8103308&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE277015(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Gea Farmaceutisk Fabrik As filed Critical Gea Farmaceutisk Fabrik As
Application granted granted Critical
Publication of ATE277015T1 publication Critical patent/ATE277015T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
AT98955389T 1997-11-14 1998-11-13 Verfahren zur herstellung von 1,4-dihydropyridine sowie in diesem verfahren verwendete verbindungen ATE277015T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK129997 1997-11-14
PCT/DK1998/000492 WO1999025688A1 (en) 1997-11-14 1998-11-13 Process for the preparation of 1,4-dihydropyridines and compounds used in this process

Publications (1)

Publication Number Publication Date
ATE277015T1 true ATE277015T1 (de) 2004-10-15

Family

ID=8103308

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98955389T ATE277015T1 (de) 1997-11-14 1998-11-13 Verfahren zur herstellung von 1,4-dihydropyridine sowie in diesem verfahren verwendete verbindungen

Country Status (11)

Country Link
EP (1) EP1030841B1 (de)
AT (1) ATE277015T1 (de)
AU (1) AU1224799A (de)
DK (1) DK1030841T3 (de)
ES (1) ES2226185T3 (de)
HU (1) HUP0100640A3 (de)
NO (1) NO314900B1 (de)
PT (1) PT1030841E (de)
RS (1) RS49711B (de)
WO (1) WO1999025688A1 (de)
ZA (1) ZA9810320B (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002054062A2 (en) 2000-12-29 2002-07-11 Pfizer Limited Reference standards and processes for determining the purity or stability of amlodipine maleate
US7335380B2 (en) 2000-12-29 2008-02-26 Synthon Ip Inc. Amlodipine free base
US6653481B2 (en) 2000-12-29 2003-11-25 Synthon Bv Process for making amlodipine
WO2002053539A1 (en) 2000-12-29 2002-07-11 Pfizer Limited Amlodipine hemimaleate
AT5874U1 (de) 2000-12-29 2003-01-27 Bioorg Bv Pharmazeutische zubereitungen enthaltend amlodipinmaleat
CA2433193C (en) 2000-12-29 2006-01-31 Pfizer Limited Amide derivative of amlodipine
MXPA03005882A (es) 2000-12-29 2005-04-19 Pfizer Ltd Derivado amida de amlodipina.
RS53403A (en) 2000-12-29 2006-10-27 Pfizer Limited Process for making amlodipine maleate
MXPA03005886A (es) 2000-12-29 2005-04-19 Pfizer Ltd Derivado de aspartato de amlodipina como antagonista del canal de calcio.
CA2433181C (en) 2000-12-29 2005-11-22 Pfizer Limited Amlodipine hemifumarate
US6680334B2 (en) 2001-08-28 2004-01-20 Pfizer Inc Crystalline material
ES2211317B1 (es) * 2002-11-18 2005-10-16 Finaf 92, S.A. Compuestos intermedios para la obtencion de principios activos antihipertensivos y procedimientos correspondientes.
CN103922996B (zh) * 2013-01-11 2019-01-04 广东东阳光药业有限公司 一种药物新型中间体及其制备方法
CN114989072B (zh) * 2022-05-27 2023-07-21 四川大学 一种不对称催化合成手性1,4-二氢吡啶化合物的方法及其应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK161312C (da) * 1982-03-11 1991-12-09 Pfizer Analogifremgangsmaade til fremstilling af 2-aminoalkoxymethyl-4-phenyl-6-methyl-1,4-dihydropyridin-3,5-dicarboxylsyreestere eller syreadditionssalte deraf samt phthalimidoderivater til anvendelse som udgangsmateriale ved fremgangsmaaden
JPS6191185A (ja) * 1984-10-11 1986-05-09 Sumitomo Seiyaku Kk 新規なオキサジアゾリル−１，４−ジヒドロピリジン誘導体
EP0225175A3 (de) * 1985-11-28 1988-12-28 FISONS plc Dihydropyridin-Derivate, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zusammensetzungen
NZ280378A (en) * 1995-11-01 1998-04-27 Apotex Inc 4-phenyl-1,4-dihydropyridine-3,5-dicarboxylic acid compounds, preparation, intermediate compounds

Also Published As

Publication number Publication date
EP1030841A1 (de) 2000-08-30
HUP0100640A2 (hu) 2001-07-30
EP1030841B1 (de) 2004-09-22
NO20002490D0 (no) 2000-05-12
HUP0100640A3 (en) 2001-11-28
DK1030841T3 (da) 2005-01-24
NO314900B1 (no) 2003-06-10
PT1030841E (pt) 2005-01-31
WO1999025688A1 (en) 1999-05-27
RS49711B (sr) 2007-12-31
AU1224799A (en) 1999-06-07
ES2226185T3 (es) 2005-03-16
NO20002490L (no) 2000-07-13
ZA9810320B (en) 2000-05-11
YU28500A (sh) 2002-10-18

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