DK1030841T3 - Fremgangsmåde til fremstilling af 1,4-dihydropyridiner og forbindelser anvendt i denne fremgangsmåde - Google Patents

Fremgangsmåde til fremstilling af 1,4-dihydropyridiner og forbindelser anvendt i denne fremgangsmåde

Info

Publication number
DK1030841T3
DK1030841T3 DK98955389T DK98955389T DK1030841T3 DK 1030841 T3 DK1030841 T3 DK 1030841T3 DK 98955389 T DK98955389 T DK 98955389T DK 98955389 T DK98955389 T DK 98955389T DK 1030841 T3 DK1030841 T3 DK 1030841T3
Authority
DK
Denmark
Prior art keywords
formula
aralkyl
cycloalkyl
alkyl
iii
Prior art date
Application number
DK98955389T
Other languages
Danish (da)
English (en)
Inventor
Gunnar Leo Karup
Soren Bols Pedersen
Herbert Fritz Preikschat
Original Assignee
Gea Farmaceutisk Fabrik As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8103308&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1030841(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Gea Farmaceutisk Fabrik As filed Critical Gea Farmaceutisk Fabrik As
Application granted granted Critical
Publication of DK1030841T3 publication Critical patent/DK1030841T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
DK98955389T 1997-11-14 1998-11-13 Fremgangsmåde til fremstilling af 1,4-dihydropyridiner og forbindelser anvendt i denne fremgangsmåde DK1030841T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK129997 1997-11-14
PCT/DK1998/000492 WO1999025688A1 (en) 1997-11-14 1998-11-13 Process for the preparation of 1,4-dihydropyridines and compounds used in this process

Publications (1)

Publication Number Publication Date
DK1030841T3 true DK1030841T3 (da) 2005-01-24

Family

ID=8103308

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98955389T DK1030841T3 (da) 1997-11-14 1998-11-13 Fremgangsmåde til fremstilling af 1,4-dihydropyridiner og forbindelser anvendt i denne fremgangsmåde

Country Status (11)

Country Link
EP (1) EP1030841B1 (de)
AT (1) ATE277015T1 (de)
AU (1) AU1224799A (de)
DK (1) DK1030841T3 (de)
ES (1) ES2226185T3 (de)
HU (1) HUP0100640A3 (de)
NO (1) NO314900B1 (de)
PT (1) PT1030841E (de)
RS (1) RS49711B (de)
WO (1) WO1999025688A1 (de)
ZA (1) ZA9810320B (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1309555T3 (da) * 2000-12-29 2005-10-24 Pfizer Ltd Metode til fremstilling af amlodipinmaleat
US7335380B2 (en) 2000-12-29 2008-02-26 Synthon Ip Inc. Amlodipine free base
WO2002054062A2 (en) 2000-12-29 2002-07-11 Pfizer Limited Reference standards and processes for determining the purity or stability of amlodipine maleate
MXPA03005882A (es) 2000-12-29 2005-04-19 Pfizer Ltd Derivado amida de amlodipina.
WO2002053538A1 (en) 2000-12-29 2002-07-11 Pfizer Limited Amlodipine fumarate
EP1309554A1 (de) 2000-12-29 2003-05-14 Synthon Licensing, Ltd. Amid-derivat von amlodipin
US6653481B2 (en) 2000-12-29 2003-11-25 Synthon Bv Process for making amlodipine
WO2002053539A1 (en) 2000-12-29 2002-07-11 Pfizer Limited Amlodipine hemimaleate
GB2372036B (en) 2000-12-29 2004-05-19 Bioorg Bv Aspartate derivative of amlodipine
AT5874U1 (de) 2000-12-29 2003-01-27 Bioorg Bv Pharmazeutische zubereitungen enthaltend amlodipinmaleat
US6680334B2 (en) 2001-08-28 2004-01-20 Pfizer Inc Crystalline material
ES2211317B1 (es) * 2002-11-18 2005-10-16 Finaf 92, S.A. Compuestos intermedios para la obtencion de principios activos antihipertensivos y procedimientos correspondientes.
CN103922996B (zh) * 2013-01-11 2019-01-04 广东东阳光药业有限公司 一种药物新型中间体及其制备方法
CN114989072B (zh) * 2022-05-27 2023-07-21 四川大学 一种不对称催化合成手性1,4-二氢吡啶化合物的方法及其应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK161312C (da) * 1982-03-11 1991-12-09 Pfizer Analogifremgangsmaade til fremstilling af 2-aminoalkoxymethyl-4-phenyl-6-methyl-1,4-dihydropyridin-3,5-dicarboxylsyreestere eller syreadditionssalte deraf samt phthalimidoderivater til anvendelse som udgangsmateriale ved fremgangsmaaden
JPS6191185A (ja) 1984-10-11 1986-05-09 Sumitomo Seiyaku Kk 新規なオキサジアゾリル−１，４−ジヒドロピリジン誘導体
EP0225175A3 (de) * 1985-11-28 1988-12-28 FISONS plc Dihydropyridin-Derivate, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zusammensetzungen
NZ280378A (en) * 1995-11-01 1998-04-27 Apotex Inc 4-phenyl-1,4-dihydropyridine-3,5-dicarboxylic acid compounds, preparation, intermediate compounds

Also Published As

Publication number Publication date
WO1999025688A1 (en) 1999-05-27
HUP0100640A2 (hu) 2001-07-30
NO314900B1 (no) 2003-06-10
ATE277015T1 (de) 2004-10-15
NO20002490L (no) 2000-07-13
EP1030841B1 (de) 2004-09-22
HUP0100640A3 (en) 2001-11-28
ES2226185T3 (es) 2005-03-16
EP1030841A1 (de) 2000-08-30
AU1224799A (en) 1999-06-07
NO20002490D0 (no) 2000-05-12
RS49711B (sr) 2007-12-31
ZA9810320B (en) 2000-05-11
PT1030841E (pt) 2005-01-31
YU28500A (sh) 2002-10-18

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