JP2006512894A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2006512894A5 JP2006512894A5 JP2004511349A JP2004511349A JP2006512894A5 JP 2006512894 A5 JP2006512894 A5 JP 2006512894A5 JP 2004511349 A JP2004511349 A JP 2004511349A JP 2004511349 A JP2004511349 A JP 2004511349A JP 2006512894 A5 JP2006512894 A5 JP 2006512894A5
- Authority
- JP
- Japan
- Prior art keywords
- fusion protein
- pharmaceutical composition
- homodimeric
- nucleic acid
- domain
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP02012742.9 | 2002-06-07 | ||
| EP02012742A EP1369128A1 (en) | 2002-06-07 | 2002-06-07 | Inhibitors of glycoprotein VI and their therapeutic use |
| PCT/EP2003/005929 WO2003104282A2 (en) | 2002-06-07 | 2003-06-05 | Immunoadhesin comprising a glycoprotein vi domain |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2006512894A JP2006512894A (ja) | 2006-04-20 |
| JP2006512894A5 true JP2006512894A5 (https=) | 2006-07-06 |
| JP4722480B2 JP4722480B2 (ja) | 2011-07-13 |
Family
ID=29433140
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004511349A Expired - Lifetime JP4722480B2 (ja) | 2002-06-07 | 2003-06-05 | 糖タンパク質ｖｉドメインを含むイムノアドヘシン |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US7514543B2 (https=) |
| EP (4) | EP1369128A1 (https=) |
| JP (1) | JP4722480B2 (https=) |
| CN (1) | CN1668721B (https=) |
| AT (1) | ATE346095T1 (https=) |
| AU (2) | AU2003250825A1 (https=) |
| CA (1) | CA2488630C (https=) |
| DE (1) | DE60309865T2 (https=) |
| DK (1) | DK1860118T3 (https=) |
| ES (2) | ES2276078T3 (https=) |
| SI (1) | SI1511770T1 (https=) |
| WO (2) | WO2003104282A2 (https=) |
| ZA (1) | ZA200409776B (https=) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20070071744A1 (en) | 2002-06-07 | 2007-03-29 | Gotz Munch | Agents which bind to epitopes of glycoprotein VI |
| EP1369128A1 (en) | 2002-06-07 | 2003-12-10 | Procorde GmbH | Inhibitors of glycoprotein VI and their therapeutic use |
| GB0511590D0 (en) * | 2005-06-07 | 2005-07-13 | Procorde Gmbh | Anti-thrombotic agents |
| US7531178B2 (en) | 2002-06-07 | 2009-05-12 | Trigen Gmbh | Immunoadhesin comprising a glycoprotein VI domain |
| WO2006061650A2 (en) * | 2004-12-10 | 2006-06-15 | Trigen Gmbh | Methods, products and uses involving platelets and/or the vasculature |
| US7645592B2 (en) | 2004-04-29 | 2010-01-12 | Otsuka Pharmaceutical Co., Ltd. | Glycoprotein VI antibodies and methods of use thereof |
| KR101194446B1 (ko) | 2004-04-29 | 2012-10-24 | 오쓰까 세이야꾸 가부시키가이샤 | 당단백 ｖｉ에 특이적인 항체 및 그의 제조방법 |
| ATE548389T1 (de) | 2004-08-03 | 2012-03-15 | Innate Pharma | Therapeutische und diagnostische verfahren und zusammensetzungen zum targeting von 4ig-b7-h3 und dem entsprechenden nk-zellen-rezeptor |
| FR2884831B1 (fr) * | 2005-04-22 | 2007-08-10 | Merck Sante Soc Par Actions Si | Methode de criblage de composes inhibiteurs de la mtp |
| EP1876240B1 (en) * | 2005-04-28 | 2012-08-22 | Mochida Pharmaceutical Co., Ltd. | Anti-human platelet membrane glycoprotein vi monoclonal antibody |
| JP5224707B2 (ja) * | 2005-04-28 | 2013-07-03 | 持田製薬株式会社 | 抗血小板膜糖蛋白質ｖｉモノクローナル抗体 |
| WO2006117910A1 (ja) | 2005-04-28 | 2006-11-09 | Mochida Pharmaceutical Co., Ltd. | 抗血小板膜糖蛋白質ⅵモノクローナル抗体 |
| CN101341406A (zh) * | 2005-12-22 | 2009-01-07 | 盐野义制药株式会社 | 急性冠状综合征的预后预测方法 |
| SG185307A1 (en) * | 2007-10-31 | 2012-11-29 | Otsuka Pharma Co Ltd | Uses of a glycoprotein vi (gpvi) inhibitor |
| ES2569610T3 (es) * | 2008-12-04 | 2016-05-11 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Método para producir plaquetas |
| PL2995315T3 (pl) * | 2009-05-15 | 2024-04-22 | University Health Network | Kompozycje i sposoby leczenia nowotworów hematologicznych celujące w oddziaływanie sirp alfa-cd47 |
| EP2397495A1 (en) * | 2010-06-21 | 2011-12-21 | Sanofi | Novel antagonist antibodies and their Fab fragments against GPVI and uses thereof |
| EP2336188A1 (en) * | 2009-12-18 | 2011-06-22 | Sanofi-Aventis | Novel antagonist antibodies and their Fab fragments against GPVI and uses thereof |
| PT2513147T (pt) | 2009-12-18 | 2016-10-11 | Sanofi Sa | Novos anticorpos antagonistas e seus fragmentos fab contra gpvi e utilizações destes |
| EP2377888A1 (en) | 2010-04-07 | 2011-10-19 | Corimmun GmbH | Fusion protein |
| ES2914814T3 (es) | 2012-12-17 | 2022-06-16 | Pf Argentum Ip Holdings Llc | Tratamiento de células enfermas CD47+ con fusiones SIRP Alfa-Fc |
| US20150338330A1 (en) * | 2012-12-20 | 2015-11-26 | Fujimori Kogyo Co., Ltd., | Method for Comprehensive Assessment of Platelet Aggregation |
| EP3424957A1 (en) | 2017-07-03 | 2019-01-09 | advanceCOR GmbH | Fusion protein |
| CN110964119A (zh) * | 2019-12-05 | 2020-04-07 | 沣潮医药科技（上海）有限公司 | 抗疟二聚体免疫粘附素、药物组合物和用途 |
| CN115768784A (zh) * | 2020-02-06 | 2023-03-07 | 勃林格殷格翰动物保健有限公司 | 用于检测抗弹状病毒抗体的多肽 |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5156840A (en) * | 1982-03-09 | 1992-10-20 | Cytogen Corporation | Amine-containing porphyrin derivatives |
| ZA887365B (en) | 1987-10-02 | 1990-05-30 | Genentech Inc | Adheson variants |
| PT88641B (pt) | 1987-10-02 | 1993-04-30 | Genentech Inc | Metodo para a preparacao de uma variante de adesao |
| US6406697B1 (en) | 1989-02-23 | 2002-06-18 | Genentech, Inc. | Hybrid immunoglobulins |
| US5116964A (en) | 1989-02-23 | 1992-05-26 | Genentech, Inc. | Hybrid immunoglobulins |
| US5525491A (en) * | 1991-02-27 | 1996-06-11 | Creative Biomolecules, Inc. | Serine-rich peptide linkers |
| GB9806806D0 (en) | 1998-03-30 | 1998-05-27 | Univ Cambridge Tech | Peptides and uses thereof |
| GB9809951D0 (en) | 1998-05-08 | 1998-07-08 | Univ Cambridge Tech | Binding molecules |
| GB9810999D0 (en) * | 1998-05-21 | 1998-07-22 | Goken Joop | Materials and methods relating to the expression of genes |
| DE60038675T2 (de) | 1999-05-07 | 2009-07-02 | Sanofi-Aventis Deutschland Gmbh | Rekombinantes plättchenkollagenrezeptorglykoprotein und dessen pharmazeutische verwendung |
| US6245527B1 (en) * | 1999-06-30 | 2001-06-12 | Millennium Pharmaceuticals, Inc. | Nucleic acid molecules encoding glycoprotein VI and recombinant uses thereof |
| US20040001826A1 (en) | 1999-06-30 | 2004-01-01 | Millennium Pharmaceuticals, Inc. | Glycoprotein VI and uses thereof |
| US7291714B1 (en) * | 1999-06-30 | 2007-11-06 | Millennium Pharmaceuticals, Inc. | Glycoprotein VI and uses thereof |
| AU7097400A (en) | 1999-09-01 | 2001-03-26 | Otsuka Pharmaceutical Co., Ltd. | Platelet membrane glycoprotein vi (gpvi) dna and protein sequences, and uses thereof |
| EP1224942A1 (en) | 2001-01-23 | 2002-07-24 | Bernhard Dr. Nieswandt | Use of JAQ1 (monoclonal antibody anti GPVI) as a medicament for the protection against thrombotic diseases |
| US7300922B2 (en) | 2001-05-25 | 2007-11-27 | Duke University | Modulators of pharmacological agents |
| WO2003008454A2 (en) | 2001-07-18 | 2003-01-30 | Merck Patent Gmbh | Glycoprotein vi fusion proteins |
| GB0130543D0 (en) | 2001-12-20 | 2002-02-06 | Univ Cambridge Tech | Human antibodies and their use |
| GB0130832D0 (en) | 2001-12-22 | 2002-02-06 | Univ Reading | Modulation of the activity of the platelet endothelial cell adhesion molecule-1 (pecam-1) |
| GB0211750D0 (en) | 2002-05-22 | 2002-07-03 | Ouwehand Willem | Abnormal blood conditions |
| US7531178B2 (en) | 2002-06-07 | 2009-05-12 | Trigen Gmbh | Immunoadhesin comprising a glycoprotein VI domain |
| EP1369128A1 (en) | 2002-06-07 | 2003-12-10 | Procorde GmbH | Inhibitors of glycoprotein VI and their therapeutic use |
| EP1538165A1 (en) | 2003-12-03 | 2005-06-08 | Procorde GmbH | Inhibitors of glycoprotein VI based on monoclonal antibody hgp 5c4 |
-
2002
- 2002-06-07 EP EP02012742A patent/EP1369128A1/en not_active Withdrawn
-
2003
- 2003-06-05 ES ES03735562T patent/ES2276078T3/es not_active Expired - Lifetime
- 2003-06-05 JP JP2004511349A patent/JP4722480B2/ja not_active Expired - Lifetime
- 2003-06-05 US US10/489,053 patent/US7514543B2/en not_active Expired - Lifetime
- 2003-06-05 AU AU2003250825A patent/AU2003250825A1/en not_active Abandoned
- 2003-06-05 CA CA2488630A patent/CA2488630C/en not_active Expired - Lifetime
- 2003-06-05 AT AT03735562T patent/ATE346095T1/de not_active IP Right Cessation
- 2003-06-05 AU AU2003236704A patent/AU2003236704B2/en not_active Expired
- 2003-06-05 EP EP03735562A patent/EP1511770B1/en not_active Expired - Lifetime
- 2003-06-05 WO PCT/EP2003/005929 patent/WO2003104282A2/en not_active Ceased
- 2003-06-05 DE DE60309865T patent/DE60309865T2/de not_active Expired - Lifetime
- 2003-06-05 EP EP06023943.1A patent/EP1860118B1/en not_active Expired - Lifetime
- 2003-06-05 WO PCT/EP2003/005919 patent/WO2003103662A2/en not_active Ceased
- 2003-06-05 SI SI200330640T patent/SI1511770T1/sl unknown
- 2003-06-05 DK DK06023943.1T patent/DK1860118T3/en active
- 2003-06-05 CN CN038172798A patent/CN1668721B/zh not_active Expired - Lifetime
- 2003-06-05 EP EP03757030A patent/EP1511480A2/en not_active Withdrawn
- 2003-06-05 ES ES06023943.1T patent/ES2527717T3/es not_active Expired - Lifetime
-
2004
- 2004-12-02 ZA ZA200409776A patent/ZA200409776B/xx unknown
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2006512894A5 (https=) | ||
| JP3280376B2 (ja) | 多価抗原結合性蛋白質 | |
| JP6101638B2 (ja) | 多価ヘテロマルチマー足場設計及び構築物 | |
| US5767260A (en) | Antigen-binding fusion proteins | |
| US8431532B2 (en) | FZD8 extracellular domains and FZD8 extracellular domain fusion molecules and treatments using same | |
| KR100280069B1 (ko) | 면역글로불린 부분을 갖는 융합 단백질, 이의 제조방법 및 이를포함하는 약제학적 조성물 | |
| JP4255618B2 (ja) | 単鎖二官能性糖タンパク質ホルモン | |
| CN108112253B (zh) | 抗癌融合多肽 | |
| JP2003512011A5 (https=) | ||
| Utani et al. | Laminin chain assembly. Specific sequences at the C terminus of the long arm are required for the formation of specific double-and triple-stranded coiled-coil structures. | |
| JP2016528295A5 (https=) | ||
| JP2003501090A5 (https=) | ||
| JP2004523205A5 (https=) | ||
| AU691607B2 (en) | Afamin: a human serum albumin-like protein | |
| RS55609B1 (sr) | Fc fuzioni proteini koji sadrže nove linkere ili aranžmane | |
| JP2018515085A (ja) | 抗がん融合ポリペプチド | |
| JPH07508178A (ja) | レセプター活性化 | |
| JP2002500886A5 (https=) | ||
| JP2017518748A5 (https=) | ||
| JP2010504336A5 (https=) | ||
| KR20050007359A (ko) | 종양 치료를 위한 면역접합체 | |
| KR20200018781A (ko) | 반감기 연장 폴리펩티드를 갖는 융합 단백질 | |
| JP2002514418A5 (https=) | ||
| CN103391787A (zh) | uPAR拮抗剂及其应用 | |
| JP2008521426A5 (https=) |