DK1773884T3 - Terapeutiske og diagnostiske fremgangsmåder og sammensætninger til targeting af 4ig-b7-h3 og dets tilsvarende nk-celle-receptor - Google Patents
Terapeutiske og diagnostiske fremgangsmåder og sammensætninger til targeting af 4ig-b7-h3 og dets tilsvarende nk-celle-receptorInfo
- Publication number
- DK1773884T3 DK1773884T3 DK05775603.3T DK05775603T DK1773884T3 DK 1773884 T3 DK1773884 T3 DK 1773884T3 DK 05775603 T DK05775603 T DK 05775603T DK 1773884 T3 DK1773884 T3 DK 1773884T3
- Authority
- DK
- Denmark
- Prior art keywords
- targeting
- therapeutic
- compositions
- similar
- protein
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2827—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against B7 molecules, e.g. CD80, CD86
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Oncology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cell Biology (AREA)
- Biomedical Technology (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Communicable Diseases (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Hematology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US59872704P | 2004-08-03 | 2004-08-03 | |
PCT/IB2005/002688 WO2006016276A2 (en) | 2004-08-03 | 2005-08-02 | Therapeutic and diagnostic methods and compositions targeting 4ig-b7-h3 and its counterpart nk cell receptor |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1773884T3 true DK1773884T3 (da) | 2012-05-21 |
Family
ID=35241619
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK05775603.3T DK1773884T3 (da) | 2004-08-03 | 2005-08-02 | Terapeutiske og diagnostiske fremgangsmåder og sammensætninger til targeting af 4ig-b7-h3 og dets tilsvarende nk-celle-receptor |
DK11186925T DK2412728T3 (da) | 2004-08-03 | 2005-08-02 | Terapeutiske præparater mod cancer, der er rettet mod 4Ig-B7-H3 |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK11186925T DK2412728T3 (da) | 2004-08-03 | 2005-08-02 | Terapeutiske præparater mod cancer, der er rettet mod 4Ig-B7-H3 |
Country Status (9)
Country | Link |
---|---|
US (3) | US7732131B2 (da) |
EP (2) | EP1773884B1 (da) |
JP (2) | JP5130044B2 (da) |
AT (1) | ATE548389T1 (da) |
AU (1) | AU2005270918B2 (da) |
CA (1) | CA2575607C (da) |
DK (2) | DK1773884T3 (da) |
ES (2) | ES2534288T3 (da) |
WO (1) | WO2006016276A2 (da) |
Families Citing this family (28)
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WO2002010187A1 (en) | 2000-07-27 | 2002-02-07 | Mayo Foundation For Medical Education And Research | B7-h3 and b7-h4, novel immunoregulatory molecules |
EP1914242A1 (en) * | 2006-10-19 | 2008-04-23 | Sanofi-Aventis | Novel anti-CD38 antibodies for the treatment of cancer |
AU2007325872B2 (en) | 2006-11-08 | 2012-12-13 | Macrogenics West, Inc. | TES7 and antibodies that bind thereto |
US7989173B2 (en) | 2006-12-27 | 2011-08-02 | The Johns Hopkins University | Detection and diagnosis of inflammatory disorders |
WO2008100934A1 (en) * | 2007-02-14 | 2008-08-21 | Mayo Foundation For Medical Education And Research | B7-h3 in cancer |
EP2252631B1 (en) | 2008-04-02 | 2016-04-13 | MacroGenics, Inc. | Bcr-complex-specific antibodies and methods of using same |
US20110110940A1 (en) * | 2008-04-15 | 2011-05-12 | Oxigene, Inc. | Methods for Enhancing the Efficacy of Vascular Disrupting Agents |
FR2937470B1 (fr) | 2008-10-16 | 2010-12-10 | Fibercryst | Systeme amplificateur optique pour laser impulsionnel a base d'un milieu a gain guidant et laser impulisionnel le comprenant |
AU2010215838A1 (en) * | 2009-02-20 | 2010-08-26 | John Wayne Cancer Institute | B7-H3 antibody coupled bead assay for detection of circulating tumor cells |
CA2772199A1 (en) | 2009-08-31 | 2011-03-03 | Amplimmune, Inc. | B7-h4 fusion proteins and methods of use thereof |
DK2496720T3 (da) | 2009-11-06 | 2020-09-28 | Univ Leland Stanford Junior | Ikke-invasiv diagnose af transplantatafstødning i organ-transplanterede patienter |
US8802091B2 (en) | 2010-03-04 | 2014-08-12 | Macrogenics, Inc. | Antibodies reactive with B7-H3 and uses thereof |
BR112012022210B1 (pt) * | 2010-03-04 | 2021-08-17 | Macrogenics, Inc | Anticorpo isolado ou seu fragmento imunorreativo, molécula de ácido nucleico, composição farmacêutica, e, uso do anticorpo isolado |
WO2012004410A1 (en) * | 2010-07-09 | 2012-01-12 | Oslo Universitetssykehus Hf | B7-h3 antagonists and taxanes |
TWI561531B (en) * | 2011-04-25 | 2016-12-11 | Daiichi Sankyo Co Ltd | Anti b7-h3 antibody |
US9487587B2 (en) | 2013-03-05 | 2016-11-08 | Macrogenics, Inc. | Bispecific molecules that are immunoreactive with immune effector cells of a companion animal that express an activating receptor and cells that express B7-H3 and uses thereof |
US10100115B2 (en) | 2014-02-14 | 2018-10-16 | Macrogenics, Inc. | Methods for the treatment of vascularizing cancers |
US10676723B2 (en) | 2015-05-11 | 2020-06-09 | David Gordon Bermudes | Chimeric protein toxins for expression by therapeutic bacteria |
CA2990520C (en) | 2015-07-24 | 2023-06-27 | Innate Pharma | Methods for detecting tissue infiltrating nk cells |
CN108136010A (zh) | 2015-10-08 | 2018-06-08 | 宏观基因有限公司 | 用于治疗癌症的联合疗法 |
CN116059390A (zh) | 2016-03-24 | 2023-05-05 | 拜耳制药股份公司 | 具有酶促可裂解基团的细胞毒性活性物质的前药 |
CR20180484A (es) | 2016-04-15 | 2019-03-05 | Macrogenics Inc | Moléculas de unón b7-h3 novedosas, conjugados anticuerpos-fármaco de los mismos y métodos de uso de los mismos |
CA3027445A1 (en) | 2016-06-15 | 2017-12-21 | Bayer Pharma Aktiengesellschaft | Specific antibody-drug-conjugates (adcs) with ksp inhibitors and anti-cd123-antibodies |
KR20190068602A (ko) | 2016-10-21 | 2019-06-18 | 이나뜨 파르마 | 항-kir3dl2 작용제에 의한 치료 |
CN110312534B (zh) | 2016-12-21 | 2023-04-04 | 拜耳制药股份公司 | 具有酶促可裂解基团的抗体-药物-缀合物(adc) |
EP3558387B1 (de) | 2016-12-21 | 2021-10-20 | Bayer Pharma Aktiengesellschaft | Spezifische antikörper-wirkstoff-konjugate (adcs) mit ksp-inhibitoren |
CN110312533B (zh) | 2016-12-21 | 2023-11-03 | 拜耳公司 | 具有酶促可裂解的基团的细胞毒性活性剂的前药 |
WO2021136240A1 (zh) * | 2019-12-30 | 2021-07-08 | 白素梅 | 人4IgB7-H3的突变编码基因及其调节免疫的应用 |
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FR401702A (fr) | 1908-08-04 | 1909-09-13 | Charles Marenghi Et Cie Soc | Dispositif permettant d'imiter mécaniquement la mandoline |
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CN104645327A (zh) | 2003-07-24 | 2015-05-27 | 依奈特制药公司 | 使用nk细胞增效化合物提高治疗性抗体功效的方法和组合物 |
-
2005
- 2005-08-02 AU AU2005270918A patent/AU2005270918B2/en active Active
- 2005-08-02 DK DK05775603.3T patent/DK1773884T3/da active
- 2005-08-02 DK DK11186925T patent/DK2412728T3/da active
- 2005-08-02 EP EP05775603A patent/EP1773884B1/en active Active
- 2005-08-02 AT AT05775603T patent/ATE548389T1/de active
- 2005-08-02 WO PCT/IB2005/002688 patent/WO2006016276A2/en active Application Filing
- 2005-08-02 CA CA2575607A patent/CA2575607C/en active Active
- 2005-08-02 EP EP11186925.1A patent/EP2412728B1/en active Active
- 2005-08-02 US US11/659,175 patent/US7732131B2/en active Active
- 2005-08-02 JP JP2007524425A patent/JP5130044B2/ja active Active
- 2005-08-02 ES ES11186925.1T patent/ES2534288T3/es active Active
- 2005-08-02 ES ES05775603T patent/ES2381557T3/es active Active
-
2010
- 2010-05-07 US US12/775,531 patent/US8465931B2/en active Active
-
2012
- 2012-06-20 JP JP2012138816A patent/JP5560301B2/ja active Active
-
2013
- 2013-06-07 US US13/912,333 patent/US20130315892A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
JP5560301B2 (ja) | 2014-07-23 |
US20080081346A1 (en) | 2008-04-03 |
EP2412728B1 (en) | 2015-01-07 |
US20130315892A1 (en) | 2013-11-28 |
EP1773884B1 (en) | 2012-03-07 |
CA2575607C (en) | 2017-07-11 |
ES2534288T3 (es) | 2015-04-21 |
CA2575607A1 (en) | 2006-02-16 |
EP2412728A2 (en) | 2012-02-01 |
WO2006016276A3 (en) | 2006-05-04 |
ES2381557T3 (es) | 2012-05-29 |
US7732131B2 (en) | 2010-06-08 |
WO2006016276A2 (en) | 2006-02-16 |
JP2012197311A (ja) | 2012-10-18 |
DK2412728T3 (da) | 2015-04-07 |
EP1773884A2 (en) | 2007-04-18 |
JP2008509130A (ja) | 2008-03-27 |
ATE548389T1 (de) | 2012-03-15 |
JP5130044B2 (ja) | 2013-01-30 |
US8465931B2 (en) | 2013-06-18 |
AU2005270918B2 (en) | 2011-03-03 |
EP2412728A3 (en) | 2012-05-02 |
US20100285531A1 (en) | 2010-11-11 |
AU2005270918A1 (en) | 2006-02-16 |
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