JP2017518748A5 - - Google Patents
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- Publication number
- JP2017518748A5 JP2017518748A5 JP2016568907A JP2016568907A JP2017518748A5 JP 2017518748 A5 JP2017518748 A5 JP 2017518748A5 JP 2016568907 A JP2016568907 A JP 2016568907A JP 2016568907 A JP2016568907 A JP 2016568907A JP 2017518748 A5 JP2017518748 A5 JP 2017518748A5
- Authority
- JP
- Japan
- Prior art keywords
- polypeptide
- glu
- gly
- arg
- lipocalin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP14169488.5 | 2014-05-22 | ||
| EP14169488 | 2014-05-22 | ||
| PCT/EP2015/061034 WO2015177175A2 (en) | 2014-05-22 | 2015-05-20 | Novel specific-binding polypeptides and uses thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020139064A Division JP7084965B2 (ja) | 2014-05-22 | 2020-08-20 | 特異的結合ポリペプチドおよびその使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017518748A JP2017518748A (ja) | 2017-07-13 |
| JP2017518748A5 true JP2017518748A5 (https=) | 2018-06-28 |
| JP6753784B2 JP6753784B2 (ja) | 2020-09-09 |
Family
ID=50771150
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016568907A Expired - Fee Related JP6753784B2 (ja) | 2014-05-22 | 2015-05-20 | 特異的結合ポリペプチドおよびその使用 |
| JP2020139064A Expired - Fee Related JP7084965B2 (ja) | 2014-05-22 | 2020-08-20 | 特異的結合ポリペプチドおよびその使用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020139064A Expired - Fee Related JP7084965B2 (ja) | 2014-05-22 | 2020-08-20 | 特異的結合ポリペプチドおよびその使用 |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US10774119B2 (https=) |
| EP (2) | EP3145945B1 (https=) |
| JP (2) | JP6753784B2 (https=) |
| KR (1) | KR20170004011A (https=) |
| CN (2) | CN113621050A (https=) |
| AU (2) | AU2015261968B2 (https=) |
| BR (1) | BR112016027024A2 (https=) |
| CA (2) | CA2949405C (https=) |
| DK (1) | DK3145945T3 (https=) |
| ES (1) | ES2823563T3 (https=) |
| MX (2) | MX384363B (https=) |
| RU (1) | RU2723034C2 (https=) |
| SG (2) | SG11201609274SA (https=) |
| WO (1) | WO2015177175A2 (https=) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014076321A1 (en) | 2012-11-19 | 2014-05-22 | Pieris Ag | Novel specific-binding polypeptides and uses thereof |
| SG11201609274SA (en) | 2014-05-22 | 2016-12-29 | Pieris Pharmaceuticals Gmbh | Novel specific-binding polypeptides and uses thereof |
| CN108699162A (zh) * | 2015-11-30 | 2018-10-23 | 皮里斯澳大利亚有限公司 | 新型抗血管生成融合多肽 |
| BR112019016989A2 (pt) | 2017-02-17 | 2020-05-26 | Denali Therapeutics Inc. | Polipeptídeos de ligação ao receptor de transferrina manipulados |
| US11077199B2 (en) | 2017-08-09 | 2021-08-03 | Massachusetts Institute Of Technology | Albumin binding peptide conjugates and methods thereof |
| SMT202300347T1 (it) * | 2017-08-10 | 2023-11-13 | Denali Therapeutics Inc | Polipeptidi ingegnerizzati che si legano al recettore della transferrina |
| CA3092551A1 (en) | 2018-03-05 | 2019-09-12 | Janssen Biotech, Inc. | Methods of treating crohn's disease with anti-il23 specific antibody |
| EP4616911A3 (en) * | 2018-05-31 | 2025-12-24 | The Chinese University of Hong Kong | Arginase albumin binding domain fusion proteins and methods of use thereof |
| EP3599245A1 (en) * | 2018-07-27 | 2020-01-29 | Dompé farmaceutici S.p.A. | Il-17a binding polypeptides and medical uses thereof |
| CN109096373B (zh) * | 2018-09-27 | 2022-06-21 | 江苏亨瑞生物医药科技有限公司 | 合成寡肽及其用途 |
| CN109180789B (zh) * | 2018-09-27 | 2022-08-19 | 上海揽微赛尔生物科技有限公司 | 一种寡肽及制药应用 |
| CN109206485B (zh) * | 2018-09-27 | 2022-04-08 | 山东聚胜生物科技有限公司 | 一种防治肺癌转移的寡肽 |
| CN109096374B (zh) * | 2018-09-27 | 2022-11-18 | 深圳乐土沃森精准医疗有限公司 | 一种抑制肺癌转移的合成寡肽 |
| AU2020253034A1 (en) | 2019-03-29 | 2021-08-19 | Pieris Pharmaceuticals Gmbh | Inhaled administration of lipocalin muteins |
| EP4146273A4 (en) * | 2020-05-05 | 2024-07-31 | Janssen Biotech, Inc. | METHODS OF TREATING CROHN'S DISEASE USING A SPECIFIC ANTI-IL23 ANTIBODY |
| CN114805546B (zh) * | 2022-06-08 | 2024-05-28 | 宁波市健康口腔医学研究院 | 一种检测口腔癌的t细胞表位多肽及其应用 |
| WO2025170982A2 (en) | 2024-02-06 | 2025-08-14 | Paragon Therapeutics, Inc. | Il-23 antibody compositions and methods of use |
| WO2025226984A1 (en) * | 2024-04-24 | 2025-10-30 | Mopac Biologics, Inc. | Human il-17 binding polypeptides |
Family Cites Families (51)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2032831T5 (es) | 1986-08-19 | 2001-02-16 | Genentech Inc | Dispositivo y dispersion para suministro intrapulmonar de factores de crecimiento polipeptidos y citoquinas. |
| JPH01215289A (ja) | 1988-02-22 | 1989-08-29 | Toa Nenryo Kogyo Kk | 遺伝子組換えによる正常ヒト血清アルブミンａの製造方法 |
| FR2649991B2 (fr) | 1988-08-05 | 1994-03-04 | Rhone Poulenc Sante | Utilisation de derives stables du plasmide pkd1 pour l'expression et la secretion de proteines heterologues dans les levures du genre kluyveromyces |
| US5728553A (en) | 1992-09-23 | 1998-03-17 | Delta Biotechnology Limited | High purity albumin and method of producing |
| ES2245780T3 (es) | 1994-05-18 | 2006-01-16 | Nektar Therapeutics | Metodos y composiciones para la formulacion de interferones como un polvo seco. |
| DE4417598A1 (de) | 1994-05-19 | 1995-12-14 | Max Planck Gesellschaft | Verwendung des Tetracyclinpromotors zur stringent regulierten Produktion von rekombinanten Proteinen in prokaryontischen Zellen |
| AU5132096A (en) | 1995-01-30 | 1996-08-21 | Terrapin Technologies, Inc. | Glubodies - multiplicities of proteins capable of binding a variety of small molecules |
| US5908621A (en) | 1995-11-02 | 1999-06-01 | Schering Corporation | Polyethylene glycol modified interferon therapy |
| US6620413B1 (en) | 1995-12-27 | 2003-09-16 | Genentech, Inc. | OB protein-polymer chimeras |
| DE19641876B4 (de) | 1996-10-10 | 2011-09-29 | Iba Gmbh | Streptavidinmuteine |
| WO1998016873A1 (en) | 1996-10-14 | 1998-04-23 | Firm Forsat Ltd. | Method for preparing dispersions of chromogenic components |
| DE19742706B4 (de) | 1997-09-26 | 2013-07-25 | Pieris Proteolab Ag | Lipocalinmuteine |
| GB9722131D0 (en) | 1997-10-20 | 1997-12-17 | Medical Res Council | Method |
| CA2233725A1 (en) | 1998-03-31 | 1999-09-30 | Hemosol Inc. | Hemoglobin-hydroxyethyl starch complexes |
| CZ298681B6 (cs) | 1998-06-08 | 2007-12-19 | F. Hoffmann-La Roche Ag | Lécivo pro lécení infekcí chronické hepatitis C |
| US6403564B1 (en) | 1998-10-16 | 2002-06-11 | Schering Corporation | Ribavirin-interferon alfa combination therapy for eradicating detectable HCV-RNA in patients having chronic hepatitis C infection |
| DE19926068C1 (de) | 1999-06-08 | 2001-01-11 | Arne Skerra | Muteine des Bilin-Bindungsproteins |
| US7211395B2 (en) | 2001-03-09 | 2007-05-01 | Dyax Corp. | Serum albumin binding moieties |
| WO2003029462A1 (en) | 2001-09-27 | 2003-04-10 | Pieris Proteolab Ag | Muteins of human neutrophil gelatinase-associated lipocalin and related proteins |
| CA2464690A1 (en) | 2001-09-27 | 2003-04-10 | Pieris Proteolab Ag | Muteins of apolipoprotein d |
| WO2005019255A1 (en) | 2003-08-25 | 2005-03-03 | Pieris Proteolab Ag | Muteins of tear lipocalin |
| US7691970B2 (en) | 2003-08-25 | 2010-04-06 | Pieris Ag | Muteins of a bilin-binding protein with affinity for a given target |
| JP2007284351A (ja) | 2004-07-27 | 2007-11-01 | Osaka Bioscience Institute | アミロイド蛋白質の凝集を抑制する物質とその作用 |
| WO2006056464A2 (en) | 2004-11-26 | 2006-06-01 | Pieris Ag | Compound with affinity for the cytotoxic t lymphocyte-associated antigen (ctla-4) |
| EP1929073A4 (en) | 2005-09-27 | 2010-03-10 | Amunix Inc | PROTEIN MEDICAMENT AND ITS USE |
| JP2009540018A (ja) | 2006-06-13 | 2009-11-19 | ザイモジェネティクス， インコーポレイテッド | Ｉｌ−１７およびｉｌ−２３アンタゴニストならびにその使用方法 |
| TW200815469A (en) * | 2006-06-23 | 2008-04-01 | Astrazeneca Ab | Compounds |
| US8313924B2 (en) * | 2006-08-01 | 2012-11-20 | Pieris Ag | Muteins of tear lipocalin and methods for obtaining the same |
| CN101516907B (zh) * | 2006-08-01 | 2015-08-26 | 皮里斯股份公司 | 泪液脂质运载蛋白的突变蛋白及其获得方法 |
| AR065420A1 (es) | 2007-02-23 | 2009-06-03 | Schering Corp | Anticuerpos anti-il-23 p19 de ingenieria |
| AR068723A1 (es) | 2007-10-05 | 2009-12-02 | Glaxo Group Ltd | Proteina que se une a antigenos que se une a il-23 humana y sus usos |
| CA2702611A1 (en) | 2007-10-19 | 2009-04-23 | Abbott Laboratories | Immunoassays and kits for the detection of ngal |
| CN106986926A (zh) * | 2008-01-30 | 2017-07-28 | 皮里斯股份公司 | 具有对人c‑met受体酪氨酸激酶的亲和性的泪脂质运载蛋白的突变蛋白及其获得方法 |
| JP5711118B2 (ja) | 2008-06-24 | 2015-04-30 | テクニッシュ ウニヴェルジテート ミュンヘン | 所与の標的に対してアフィニティーを有するｈＮＧＡＬおよび類縁タンパク質のムテイン |
| EP2330897A4 (en) * | 2008-09-18 | 2013-11-27 | Univ Columbia | NGAL-BINDING SIDEROPHORES AND THEIR USE FOR THE TREATMENT OF IRON DEFICIENCY AND IRON SURPLUS |
| BR112012013662B1 (pt) | 2009-12-07 | 2022-08-02 | Pieris Pharmaceuticals Gmbh | Muteínas de lipocalina associada à gelatinase de neutrófilo humano (lcn2, hngal), seu uso e seus métodos de geração e produção, molécula de ácido nucleico, célula hospedeira, composição farmacêutica e kit de diagnóstico ou analítico |
| RU2569745C2 (ru) | 2010-06-08 | 2015-11-27 | Пиерис АГ | Мутеины липокалина слезы, связывающие альфа il-4 r |
| MX2013000314A (es) | 2010-07-09 | 2013-01-29 | Affibody Ab | Polipeptidos. |
| NZ606584A (en) | 2010-08-16 | 2014-10-31 | Pieris Ag | Binding proteins for hepcidin |
| US9260492B2 (en) | 2010-11-15 | 2016-02-16 | Pieris Ag | Muteins of human lipocalin 2 with affinity for glypican-3 (GPC-3) |
| GB201100282D0 (en) * | 2011-01-07 | 2011-02-23 | Ucb Pharma Sa | Biological methods |
| UA117218C2 (uk) * | 2011-05-05 | 2018-07-10 | Мерк Патент Гмбх | Поліпептид, спрямований проти il-17a, il-17f та/або il17-a/f |
| ES2710384T3 (es) * | 2011-12-13 | 2019-04-24 | Pieris Pharmaceuticals Gmbh | Procedimientos para la prevención o el tratamiento de determinados trastornos mediante la inhibición de la unión de IL-4 y/o IL-13 a sus respectivos receptores |
| WO2014076321A1 (en) * | 2012-11-19 | 2014-05-22 | Pieris Ag | Novel specific-binding polypeptides and uses thereof |
| EP3094650A2 (en) * | 2014-01-13 | 2016-11-23 | Pieris Pharmaceuticals GmbH | Multi-specific polypeptide useful for localized tumor immunomodulation |
| SG11201609274SA (en) | 2014-05-22 | 2016-12-29 | Pieris Pharmaceuticals Gmbh | Novel specific-binding polypeptides and uses thereof |
| JP6839087B2 (ja) | 2015-01-28 | 2021-03-03 | ピエリス ファーマシューティカルズ ゲーエムベーハー | 血管新生に特異的な新規のタンパク質 |
| TN2017000348A1 (en) | 2015-02-18 | 2019-01-16 | Sanofi Sa | Novel proteins specific for pyoverdine and pyochelin |
| KR102734408B1 (ko) | 2015-05-04 | 2024-11-27 | 피어이스 파마슈티컬즈 게엠베하 | Cd137에 특이적인 신규한 단백질 |
| AU2016262838B2 (en) | 2015-05-18 | 2020-10-08 | Pieris Pharmaceuticals Gmbh | Muteins of human lipocalin 2 with affinity for Glypican-3 (GPC3) |
| TW201725212A (zh) | 2015-12-10 | 2017-07-16 | 第一三共股份有限公司 | 特異性於降鈣素基因相關胜肽的新穎蛋白 |
-
2015
- 2015-05-20 SG SG11201609274SA patent/SG11201609274SA/en unknown
- 2015-05-20 EP EP15727573.6A patent/EP3145945B1/en active Active
- 2015-05-20 CA CA2949405A patent/CA2949405C/en active Active
- 2015-05-20 AU AU2015261968A patent/AU2015261968B2/en not_active Ceased
- 2015-05-20 WO PCT/EP2015/061034 patent/WO2015177175A2/en not_active Ceased
- 2015-05-20 RU RU2016149596A patent/RU2723034C2/ru active
- 2015-05-20 ES ES15727573T patent/ES2823563T3/es active Active
- 2015-05-20 CA CA3170782A patent/CA3170782A1/en active Pending
- 2015-05-20 DK DK15727573.6T patent/DK3145945T3/da active
- 2015-05-20 CN CN202110703906.XA patent/CN113621050A/zh active Pending
- 2015-05-20 EP EP20185401.5A patent/EP3789397B1/en active Active
- 2015-05-20 BR BR112016027024A patent/BR112016027024A2/pt not_active Application Discontinuation
- 2015-05-20 JP JP2016568907A patent/JP6753784B2/ja not_active Expired - Fee Related
- 2015-05-20 KR KR1020167035964A patent/KR20170004011A/ko not_active Ceased
- 2015-05-20 SG SG10201912019WA patent/SG10201912019WA/en unknown
- 2015-05-20 CN CN201580040321.7A patent/CN106573964B/zh not_active Expired - Fee Related
- 2015-05-20 MX MX2016015235A patent/MX384363B/es unknown
- 2015-05-20 US US15/312,094 patent/US10774119B2/en not_active Expired - Fee Related
-
2016
- 2016-11-18 MX MX2021008318A patent/MX2021008318A/es unknown
-
2019
- 2019-02-13 AU AU2019201007A patent/AU2019201007B2/en not_active Ceased
-
2020
- 2020-08-06 US US16/987,218 patent/US11345728B2/en active Active
- 2020-08-20 JP JP2020139064A patent/JP7084965B2/ja not_active Expired - Fee Related
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