JP2018532372A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2018532372A5 JP2018532372A5 JP2018501349A JP2018501349A JP2018532372A5 JP 2018532372 A5 JP2018532372 A5 JP 2018532372A5 JP 2018501349 A JP2018501349 A JP 2018501349A JP 2018501349 A JP2018501349 A JP 2018501349A JP 2018532372 A5 JP2018532372 A5 JP 2018532372A5
- Authority
- JP
- Japan
- Prior art keywords
- lipocalin mutein
- ala
- asp
- lipocalin
- glu
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP15176740.7 | 2015-07-15 | ||
| EP15176740 | 2015-07-15 | ||
| PCT/EP2016/066909 WO2017009456A1 (en) | 2015-07-15 | 2016-07-15 | Novel proteins specific for lag-3 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018532372A JP2018532372A (ja) | 2018-11-08 |
| JP2018532372A5 true JP2018532372A5 (https=) | 2019-08-22 |
| JP7108535B2 JP7108535B2 (ja) | 2022-07-28 |
Family
ID=53719645
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018501349A Expired - Fee Related JP7108535B2 (ja) | 2015-07-15 | 2016-07-15 | Ｌａｇ－３に特異的な新規タンパク質 |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US10501510B2 (https=) |
| EP (1) | EP3322433B1 (https=) |
| JP (1) | JP7108535B2 (https=) |
| KR (1) | KR20180029238A (https=) |
| CN (1) | CN108348573A (https=) |
| AU (1) | AU2016293101B2 (https=) |
| BR (1) | BR112017026292A2 (https=) |
| CA (1) | CA2988831A1 (https=) |
| EA (1) | EA201890198A1 (https=) |
| MX (1) | MX2018000447A (https=) |
| WO (1) | WO2017009456A1 (https=) |
| ZA (1) | ZA201708041B (https=) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2017009456A1 (en) | 2015-07-15 | 2017-01-19 | Pieris Pharmaceuticals Gmbh | Novel proteins specific for lag-3 |
| HRP20210602T1 (hr) | 2016-06-20 | 2021-05-14 | F-Star Delta Limited | Vezujuće molekule koje vežu pd-l1 i lag-3 |
| SG11201811184UA (en) | 2016-06-20 | 2019-01-30 | F Star Beta Ltd | Lag -3 binding members |
| GB201612520D0 (en) | 2016-07-19 | 2016-08-31 | F-Star Beta Ltd | Binding molecules |
| CA3050194A1 (en) * | 2017-01-18 | 2018-07-26 | Pieris Pharmaceuticals Gmbh | Lipocalin muteins with binding affinity for lag-3 |
| EP3728316B1 (en) | 2017-12-19 | 2025-02-26 | invoX Pharma Limited | Fc binding fragments comprising a pd-l1 antigen-binding site |
| ES3044118T3 (en) | 2018-07-12 | 2025-11-26 | Invox Pharma Ltd | Antibody molecules that bind cd137 and ox40 |
| GB201811410D0 (en) | 2018-07-12 | 2018-08-29 | F Star Beta Ltd | OX40 Binding molecules |
| GB201811415D0 (en) | 2018-07-12 | 2018-08-29 | F Star Beta Ltd | Anti-Mesothelin Anti bodies |
| GB201811403D0 (en) | 2018-07-12 | 2018-08-29 | F Star Beta Ltd | Antibody molecules |
| PT3820569T (pt) | 2018-07-12 | 2025-01-14 | Invox Pharma Ltd | Moléculas de anticorpo que se ligam a pd-l1 e cd137 |
| GB201811408D0 (en) | 2018-07-12 | 2018-08-29 | F Star Beta Ltd | CD137 Binding Molecules |
| GB201811404D0 (en) | 2018-07-12 | 2018-08-29 | F Star Beta Ltd | Anti-CD137 Antibodies |
| GB201811450D0 (en) | 2018-07-12 | 2018-08-29 | F Star Delta Ltd | Mesothelin and CD137 binding molecules |
| EP3946417A1 (en) * | 2019-03-29 | 2022-02-09 | Pieris Pharmaceuticals GmbH | Inhaled administration of lipocalin muteins |
| EP4161957A1 (en) | 2020-06-05 | 2023-04-12 | Pieris Pharmaceuticals GmbH | Multimeric immunomodulator targeting 4-1bb |
| WO2023118497A1 (en) | 2021-12-22 | 2023-06-29 | Pieris Pharmaceuticals Gmbh | Novel il-18 variants |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH01215289A (ja) | 1988-02-22 | 1989-08-29 | Toa Nenryo Kogyo Kk | 遺伝子組換えによる正常ヒト血清アルブミンａの製造方法 |
| FR2649991B2 (fr) | 1988-08-05 | 1994-03-04 | Rhone Poulenc Sante | Utilisation de derives stables du plasmide pkd1 pour l'expression et la secretion de proteines heterologues dans les levures du genre kluyveromyces |
| US5728553A (en) | 1992-09-23 | 1998-03-17 | Delta Biotechnology Limited | High purity albumin and method of producing |
| US5908621A (en) | 1995-11-02 | 1999-06-01 | Schering Corporation | Polyethylene glycol modified interferon therapy |
| US6620413B1 (en) | 1995-12-27 | 2003-09-16 | Genentech, Inc. | OB protein-polymer chimeras |
| DE19742706B4 (de) | 1997-09-26 | 2013-07-25 | Pieris Proteolab Ag | Lipocalinmuteine |
| GB9722131D0 (en) | 1997-10-20 | 1997-12-17 | Medical Res Council | Method |
| CA2233725A1 (en) | 1998-03-31 | 1999-09-30 | Hemosol Inc. | Hemoglobin-hydroxyethyl starch complexes |
| DK1087778T3 (da) | 1998-06-08 | 2005-12-19 | Hoffmann La Roche | Anvendelse af PEG-IFN-alfa og Ribavirin til behandling af kronisk hepatitis C |
| US6403564B1 (en) | 1998-10-16 | 2002-06-11 | Schering Corporation | Ribavirin-interferon alfa combination therapy for eradicating detectable HCV-RNA in patients having chronic hepatitis C infection |
| AU4505399A (en) | 1999-06-02 | 2000-12-28 | Abb Research Ltd | Coating composition for high temperature protection |
| AU2002335930B2 (en) | 2001-03-09 | 2005-07-28 | Morphosys Ag | Serum albumin binding moieties |
| WO2003029471A1 (en) | 2001-09-27 | 2003-04-10 | Pieris Proteolab Ag | Muteins of apolipoprotein d |
| PL1897548T5 (pl) * | 2003-02-28 | 2025-03-17 | The Johns Hopkins University | Regulacja komórek T |
| WO2005019255A1 (en) | 2003-08-25 | 2005-03-03 | Pieris Proteolab Ag | Muteins of tear lipocalin |
| US7892827B2 (en) | 2004-11-26 | 2011-02-22 | Pieris Ag | Compound with affinity for the cytotoxic T lymphocyte-associated antigen (CTLA-4) |
| JP2009509535A (ja) | 2005-09-27 | 2009-03-12 | アムニクス， インコーポレイテッド | タンパク様薬剤およびその使用 |
| US8598317B2 (en) | 2006-03-20 | 2013-12-03 | Technische Universitaet Muenchen | Muteins of tear lipocalin with affinity for the T-cell coreceptor CD4 |
| CN101932598B (zh) * | 2008-01-30 | 2016-12-21 | 皮里斯股份公司 | 具有对人c-met受体酪氨酸激酶的亲和性的泪脂质运载蛋白的突变蛋白及其获得方法 |
| EP3842058B1 (en) | 2011-12-13 | 2023-08-23 | Pieris Pharmaceuticals GmbH | Methods for preventing or treating certain disorders by inhibiting binding of il-4 and/or il-13 to their respective receptors |
| US9522940B2 (en) | 2012-05-23 | 2016-12-20 | Pieris Pharmaceuticals Gmbh | Lipocalin muteins with binding-affinity for glypican-3 (GPC-3) and use of lipocalin muteins for target-specific delivery to cells expressing GPC-3 |
| US10526384B2 (en) * | 2012-11-19 | 2020-01-07 | Pieris Pharmaceuticals Gmbh | Interleukin-17A-specific and interleukin-23-specific binding polypeptides and uses thereof |
| AU2015205530B8 (en) | 2014-01-13 | 2019-09-19 | Pieris Pharmaceuticals Gmbh | Multi-specific polypeptide useful for localized tumor immunomodulation |
| EP3298030B1 (en) | 2015-05-18 | 2023-01-18 | Pieris Pharmaceuticals GmbH | Anti-cancer fusion polypeptide |
| WO2017009456A1 (en) | 2015-07-15 | 2017-01-19 | Pieris Pharmaceuticals Gmbh | Novel proteins specific for lag-3 |
| CA3050194A1 (en) | 2017-01-18 | 2018-07-26 | Pieris Pharmaceuticals Gmbh | Lipocalin muteins with binding affinity for lag-3 |
-
2016
- 2016-07-15 WO PCT/EP2016/066909 patent/WO2017009456A1/en not_active Ceased
- 2016-07-15 EA EA201890198A patent/EA201890198A1/ru unknown
- 2016-07-15 CA CA2988831A patent/CA2988831A1/en active Pending
- 2016-07-15 BR BR112017026292A patent/BR112017026292A2/pt not_active IP Right Cessation
- 2016-07-15 EP EP16742220.3A patent/EP3322433B1/en active Active
- 2016-07-15 MX MX2018000447A patent/MX2018000447A/es unknown
- 2016-07-15 CN CN201680040702.XA patent/CN108348573A/zh active Pending
- 2016-07-15 AU AU2016293101A patent/AU2016293101B2/en not_active Ceased
- 2016-07-15 US US15/744,531 patent/US10501510B2/en active Active
- 2016-07-15 KR KR1020187004176A patent/KR20180029238A/ko not_active Ceased
- 2016-07-15 JP JP2018501349A patent/JP7108535B2/ja not_active Expired - Fee Related
-
2017
- 2017-11-27 ZA ZA2017/08041A patent/ZA201708041B/en unknown
-
2019
- 2019-10-30 US US16/669,281 patent/US10927156B2/en not_active Expired - Fee Related
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2018532372A5 (https=) | ||
| JP2018519802A5 (https=) | ||
| JP2018515084A5 (https=) | ||
| JP2014502149A5 (https=) | ||
| JP2017518748A5 (https=) | ||
| RU2016149596A (ru) | Новые полипептиды со специфическим связыванием и пути их применения | |
| Tai et al. | A bifunctional fusion protein containing Fc-binding fragment B of staphylococcal protein A amino-terminal to antidigoxin single-chain Fv | |
| CN109641046B (zh) | 单链可变片段cd3结合蛋白质 | |
| JP2020505948A5 (https=) | ||
| CN110437320B (zh) | 多肽 | |
| JP3474574B2 (ja) | 結合特異性を有する組換ジスルフィド安定化ポリペプチドフラグメント | |
| JP2018526989A5 (https=) | ||
| RU2019122482A (ru) | Мутеины липокалина с аффинностью связывания в отношении lag-3 | |
| JP2019506140A5 (https=) | ||
| CN114423284A (zh) | T细胞调节多肽及其使用方法 | |
| RU2017128105A (ru) | Новые белки, специфические в отношении ангиогенеза | |
| JP2018509887A5 (https=) | ||
| CN114539411B (zh) | 一种ror1抗体或其抗原结合片段 | |
| JP2013512683A5 (https=) | ||
| JP2017527272A5 (https=) | ||
| KR20160058085A (ko) | 고안정성의 t 세포 수용체 및 이의 제조방법과 응용 | |
| JP2002542157A5 (https=) | ||
| JP2018519803A5 (https=) | ||
| KR20150036700A (ko) | Cd22에 대해 특이적인 항체 및 이들의 사용 방법 | |
| CN113286609A (zh) | 多聚体t细胞调节多肽及其使用方法 |