JP2018532372A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2018532372A5 JP2018532372A5 JP2018501349A JP2018501349A JP2018532372A5 JP 2018532372 A5 JP2018532372 A5 JP 2018532372A5 JP 2018501349 A JP2018501349 A JP 2018501349A JP 2018501349 A JP2018501349 A JP 2018501349A JP 2018532372 A5 JP2018532372 A5 JP 2018532372A5
- Authority
- JP
- Japan
- Prior art keywords
- lipocalin mutein
- ala
- asp
- lipocalin
- glu
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP15176740 | 2015-07-15 | ||
| EP15176740.7 | 2015-07-15 | ||
| PCT/EP2016/066909 WO2017009456A1 (en) | 2015-07-15 | 2016-07-15 | Novel proteins specific for lag-3 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018532372A JP2018532372A (ja) | 2018-11-08 |
| JP2018532372A5 true JP2018532372A5 (https=) | 2019-08-22 |
| JP7108535B2 JP7108535B2 (ja) | 2022-07-28 |
Family
ID=53719645
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018501349A Expired - Fee Related JP7108535B2 (ja) | 2015-07-15 | 2016-07-15 | Ｌａｇ－３に特異的な新規タンパク質 |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US10501510B2 (https=) |
| EP (1) | EP3322433B1 (https=) |
| JP (1) | JP7108535B2 (https=) |
| KR (1) | KR20180029238A (https=) |
| CN (1) | CN108348573A (https=) |
| AU (1) | AU2016293101B2 (https=) |
| BR (1) | BR112017026292A2 (https=) |
| CA (1) | CA2988831A1 (https=) |
| EA (1) | EA201890198A1 (https=) |
| MX (1) | MX2018000447A (https=) |
| WO (1) | WO2017009456A1 (https=) |
| ZA (1) | ZA201708041B (https=) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20180029238A (ko) | 2015-07-15 | 2018-03-20 | 피어이스 파마슈티컬즈 게엠베하 | Lag-3에 특이적인 신규 단백질 |
| KR20190022632A (ko) | 2016-06-20 | 2019-03-06 | 에프-스타 베타 리미티드 | Lag-3 결합 구성원 |
| KR102664891B1 (ko) | 2016-06-20 | 2024-05-13 | 에프-스타 테라퓨틱스 리미티드 | Pd-l1 및 lag-3에 결합하는 결합 분자 |
| GB201612520D0 (en) | 2016-07-19 | 2016-08-31 | F-Star Beta Ltd | Binding molecules |
| WO2018134274A1 (en) | 2017-01-18 | 2018-07-26 | Pieris Pharmaceuticals Gmbh | Lipocalin muteins with binding affinity for lag-3 |
| WO2019121906A1 (en) | 2017-12-19 | 2019-06-27 | F-Star Beta Limited | Specific pd-l1 binding sequences inserted in a ch3 domain |
| GB201811450D0 (en) | 2018-07-12 | 2018-08-29 | F Star Delta Ltd | Mesothelin and CD137 binding molecules |
| GB201811410D0 (en) | 2018-07-12 | 2018-08-29 | F Star Beta Ltd | OX40 Binding molecules |
| GB201811408D0 (en) | 2018-07-12 | 2018-08-29 | F Star Beta Ltd | CD137 Binding Molecules |
| PL3820569T3 (pl) | 2018-07-12 | 2025-07-14 | Invox Pharma Limited | Cząsteczki przeciwciał, które wiążą PD-L1 oraz CD137 |
| GB201811404D0 (en) | 2018-07-12 | 2018-08-29 | F Star Beta Ltd | Anti-CD137 Antibodies |
| GB201811403D0 (en) | 2018-07-12 | 2018-08-29 | F Star Beta Ltd | Antibody molecules |
| GB201811415D0 (en) | 2018-07-12 | 2018-08-29 | F Star Beta Ltd | Anti-Mesothelin Anti bodies |
| BR112021000282A2 (pt) | 2018-07-12 | 2021-04-06 | F-Star Beta Limited | Moléculas de anticorpo que se ligam a cd137 e ox40 |
| AU2020253034A1 (en) | 2019-03-29 | 2021-08-19 | Pieris Pharmaceuticals Gmbh | Inhaled administration of lipocalin muteins |
| AU2021285201A1 (en) | 2020-06-05 | 2022-11-24 | Pieris Pharmaceuticals Gmbh | Multimeric immunomodulator targeting 4-1BB |
| WO2023118497A1 (en) | 2021-12-22 | 2023-06-29 | Pieris Pharmaceuticals Gmbh | Novel il-18 variants |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH01215289A (ja) | 1988-02-22 | 1989-08-29 | Toa Nenryo Kogyo Kk | 遺伝子組換えによる正常ヒト血清アルブミンａの製造方法 |
| FR2649991B2 (fr) | 1988-08-05 | 1994-03-04 | Rhone Poulenc Sante | Utilisation de derives stables du plasmide pkd1 pour l'expression et la secretion de proteines heterologues dans les levures du genre kluyveromyces |
| US5728553A (en) | 1992-09-23 | 1998-03-17 | Delta Biotechnology Limited | High purity albumin and method of producing |
| US5908621A (en) | 1995-11-02 | 1999-06-01 | Schering Corporation | Polyethylene glycol modified interferon therapy |
| US6620413B1 (en) | 1995-12-27 | 2003-09-16 | Genentech, Inc. | OB protein-polymer chimeras |
| DE19742706B4 (de) | 1997-09-26 | 2013-07-25 | Pieris Proteolab Ag | Lipocalinmuteine |
| GB9722131D0 (en) | 1997-10-20 | 1997-12-17 | Medical Res Council | Method |
| CA2233725A1 (en) | 1998-03-31 | 1999-09-30 | Hemosol Inc. | Hemoglobin-hydroxyethyl starch complexes |
| CZ298681B6 (cs) | 1998-06-08 | 2007-12-19 | F. Hoffmann-La Roche Ag | Lécivo pro lécení infekcí chronické hepatitis C |
| US6403564B1 (en) | 1998-10-16 | 2002-06-11 | Schering Corporation | Ribavirin-interferon alfa combination therapy for eradicating detectable HCV-RNA in patients having chronic hepatitis C infection |
| AU4505399A (en) | 1999-06-02 | 2000-12-28 | Abb Research Ltd | Coating composition for high temperature protection |
| US7211395B2 (en) | 2001-03-09 | 2007-05-01 | Dyax Corp. | Serum albumin binding moieties |
| CA2464690A1 (en) | 2001-09-27 | 2003-04-10 | Pieris Proteolab Ag | Muteins of apolipoprotein d |
| FI1897548T4 (fi) | 2003-02-28 | 2024-09-03 | The Johns Hopkins University | T-solujen säätely |
| WO2005019255A1 (en) | 2003-08-25 | 2005-03-03 | Pieris Proteolab Ag | Muteins of tear lipocalin |
| WO2006056464A2 (en) | 2004-11-26 | 2006-06-01 | Pieris Ag | Compound with affinity for the cytotoxic t lymphocyte-associated antigen (ctla-4) |
| EP1929073A4 (en) | 2005-09-27 | 2010-03-10 | Amunix Inc | PROTEIN MEDICAMENT AND ITS USE |
| WO2007107563A2 (en) * | 2006-03-20 | 2007-09-27 | Technische Universität München | Muteins of tear lipocalin with affinity for the t-cell coreceptor cd4 |
| CN106986926A (zh) * | 2008-01-30 | 2017-07-28 | 皮里斯股份公司 | 具有对人c‑met受体酪氨酸激酶的亲和性的泪脂质运载蛋白的突变蛋白及其获得方法 |
| ES2710384T3 (es) * | 2011-12-13 | 2019-04-24 | Pieris Pharmaceuticals Gmbh | Procedimientos para la prevención o el tratamiento de determinados trastornos mediante la inhibición de la unión de IL-4 y/o IL-13 a sus respectivos receptores |
| WO2013174783A1 (en) | 2012-05-23 | 2013-11-28 | Pieris Ag | Lipocalin muteins with binding-affinity for glypican-3 (gpc-3) and use of lipocalin muteins for target-specific delivery to cells expressing gpc-3 |
| WO2014076321A1 (en) * | 2012-11-19 | 2014-05-22 | Pieris Ag | Novel specific-binding polypeptides and uses thereof |
| EP3094650A2 (en) * | 2014-01-13 | 2016-11-23 | Pieris Pharmaceuticals GmbH | Multi-specific polypeptide useful for localized tumor immunomodulation |
| MX390894B (es) | 2015-05-18 | 2025-03-21 | Pieris Pharmaceuticals Gmbh | Polipéptido de fusión anti-cáncer. |
| KR20180029238A (ko) | 2015-07-15 | 2018-03-20 | 피어이스 파마슈티컬즈 게엠베하 | Lag-3에 특이적인 신규 단백질 |
| WO2018134274A1 (en) | 2017-01-18 | 2018-07-26 | Pieris Pharmaceuticals Gmbh | Lipocalin muteins with binding affinity for lag-3 |
-
2016
- 2016-07-15 KR KR1020187004176A patent/KR20180029238A/ko not_active Ceased
- 2016-07-15 BR BR112017026292A patent/BR112017026292A2/pt not_active IP Right Cessation
- 2016-07-15 CA CA2988831A patent/CA2988831A1/en active Pending
- 2016-07-15 EP EP16742220.3A patent/EP3322433B1/en active Active
- 2016-07-15 JP JP2018501349A patent/JP7108535B2/ja not_active Expired - Fee Related
- 2016-07-15 CN CN201680040702.XA patent/CN108348573A/zh active Pending
- 2016-07-15 EA EA201890198A patent/EA201890198A1/ru unknown
- 2016-07-15 AU AU2016293101A patent/AU2016293101B2/en not_active Ceased
- 2016-07-15 MX MX2018000447A patent/MX2018000447A/es unknown
- 2016-07-15 US US15/744,531 patent/US10501510B2/en active Active
- 2016-07-15 WO PCT/EP2016/066909 patent/WO2017009456A1/en not_active Ceased
-
2017
- 2017-11-27 ZA ZA2017/08041A patent/ZA201708041B/en unknown
-
2019
- 2019-10-30 US US16/669,281 patent/US10927156B2/en not_active Expired - Fee Related
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2018532372A5 (https=) | ||
| JP2018519802A5 (https=) | ||
| JP2018515084A5 (https=) | ||
| JP2014502149A5 (https=) | ||
| JP2017518748A5 (https=) | ||
| RU2016149596A (ru) | Новые полипептиды со специфическим связыванием и пути их применения | |
| Tai et al. | A bifunctional fusion protein containing Fc-binding fragment B of staphylococcal protein A amino-terminal to antidigoxin single-chain Fv | |
| CN109641046B (zh) | 单链可变片段cd3结合蛋白质 | |
| JP2020505948A5 (https=) | ||
| CN110437320B (zh) | 多肽 | |
| JP3474574B2 (ja) | 結合特異性を有する組換ジスルフィド安定化ポリペプチドフラグメント | |
| JP2018526989A5 (https=) | ||
| RU2019122482A (ru) | Мутеины липокалина с аффинностью связывания в отношении lag-3 | |
| JP2019506140A5 (https=) | ||
| CN114423284A (zh) | T细胞调节多肽及其使用方法 | |
| RU2017128105A (ru) | Новые белки, специфические в отношении ангиогенеза | |
| JP2018509887A5 (https=) | ||
| CN114539411B (zh) | 一种ror1抗体或其抗原结合片段 | |
| JP2013512683A5 (https=) | ||
| JP2017515457A (ja) | ＴＮＦαに対する結合メンバー | |
| JP2017527272A5 (https=) | ||
| KR20160058085A (ko) | 고안정성의 t 세포 수용체 및 이의 제조방법과 응용 | |
| JP2002542157A5 (https=) | ||
| JP2018519803A5 (https=) | ||
| KR20150036700A (ko) | Cd22에 대해 특이적인 항체 및 이들의 사용 방법 |