|
UA117466C2
(uk)
|
2012-12-13 |
2018-08-10 |
Мерк Шарп Енд Доме Корп. |
СТАБІЛЬНИЙ СКЛАД У ВИГЛЯДІ РОЗЧИНУ АНТИТІЛА ДО IL-23p19
|
|
US9974845B2
(en)
|
2013-02-22 |
2018-05-22 |
Curevac Ag |
Combination of vaccination and inhibition of the PD-1 pathway
|
|
MX383464B
(es)
|
2015-07-13 |
2025-03-14 |
Cytomx Therapeutics Inc |
Anticuerpos anti-pd-1, anticuerpos anti-pd-1 activables, y métodos de uso de los mismos.
|
|
SG11201811184UA
(en)
|
2016-06-20 |
2019-01-30 |
F Star Beta Ltd |
Lag -3 binding members
|
|
HRP20210602T1
(hr)
|
2016-06-20 |
2021-05-14 |
F-Star Delta Limited |
Vezujuće molekule koje vežu pd-l1 i lag-3
|
|
GB201612520D0
(en)
|
2016-07-19 |
2016-08-31 |
F-Star Beta Ltd |
Binding molecules
|
|
JP7066696B2
(ja)
|
2016-10-11 |
2022-05-13 |
アジェナス インコーポレイテッド |
抗lag-3抗体及びその使用方法
|
|
WO2018134279A1
(en)
*
|
2017-01-18 |
2018-07-26 |
Pieris Pharmaceuticals Gmbh |
Novel fusion polypeptides specific for lag-3 and pd-1
|
|
JP2020514370A
(ja)
*
|
2017-03-17 |
2020-05-21 |
キュアバック アーゲー |
組合せ抗癌療法のためのrnaワクチン及び免疫チェックポイント阻害剤
|
|
CN110678200B
(zh)
|
2017-05-30 |
2024-05-17 |
百时美施贵宝公司 |
包含抗lag-3抗体或抗lag-3抗体和抗pd-1或抗pd-l1抗体的组合物
|
|
ES2965352T3
(es)
|
2017-05-30 |
2024-04-12 |
Bristol Myers Squibb Co |
Tratamiento de tumores positivos a gen 3 de activación de linfocitos (LAG-3)
|
|
JP2020522495A
(ja)
|
2017-05-30 |
2020-07-30 |
ブリストル−マイヤーズ スクイブ カンパニーBristol−Myers Squibb Company |
抗lag−3抗体、pd−1経路阻害剤および免疫療法剤の組み合わせを含む組成物
|
|
EP3728316B1
(en)
|
2017-12-19 |
2025-02-26 |
invoX Pharma Limited |
Fc binding fragments comprising a pd-l1 antigen-binding site
|
|
WO2019149716A1
(en)
*
|
2018-01-31 |
2019-08-08 |
F. Hoffmann-La Roche Ag |
Bispecific antibodies comprising an antigen-binding site binding to lag3
|
|
FR3078536A1
(fr)
*
|
2018-03-05 |
2019-09-06 |
Peptinov Sas |
Composition vaccinale anti-pd-1
|
|
US20210115138A1
(en)
*
|
2018-03-20 |
2021-04-22 |
WuXi Biologics Ireland Limited |
Novel bispecific pd-1/lag-3 antibody molecules
|
|
TW202003567A
(zh)
|
2018-03-30 |
2020-01-16 |
大陸商南京傳奇生物科技有限公司 |
針對lag-3之單一結構域抗體及其用途
|
|
ES3044118T3
(en)
|
2018-07-12 |
2025-11-26 |
Invox Pharma Ltd |
Antibody molecules that bind cd137 and ox40
|
|
GB201811404D0
(en)
|
2018-07-12 |
2018-08-29 |
F Star Beta Ltd |
Anti-CD137 Antibodies
|
|
GB201811415D0
(en)
|
2018-07-12 |
2018-08-29 |
F Star Beta Ltd |
Anti-Mesothelin Anti bodies
|
|
GB201811450D0
(en)
|
2018-07-12 |
2018-08-29 |
F Star Delta Ltd |
Mesothelin and CD137 binding molecules
|
|
GB201811408D0
(en)
|
2018-07-12 |
2018-08-29 |
F Star Beta Ltd |
CD137 Binding Molecules
|
|
GB201811403D0
(en)
|
2018-07-12 |
2018-08-29 |
F Star Beta Ltd |
Antibody molecules
|
|
GB201811410D0
(en)
|
2018-07-12 |
2018-08-29 |
F Star Beta Ltd |
OX40 Binding molecules
|
|
PT3820569T
(pt)
|
2018-07-12 |
2025-01-14 |
Invox Pharma Ltd |
Moléculas de anticorpo que se ligam a pd-l1 e cd137
|
|
WO2020021061A1
(en)
*
|
2018-07-26 |
2020-01-30 |
Pieris Pharmaceuticals Gmbh |
Humanized anti-pd-1 antibodies and uses thereof
|
|
CN112739371A
(zh)
|
2018-07-26 |
2021-04-30 |
百时美施贵宝公司 |
用于治疗癌症的lag-3组合疗法
|
|
LT4445958T
(lt)
|
2018-10-19 |
2025-12-10 |
Bristol-Myers Squibb Company |
Kompleksinė terapija, skirta melanomai gydyti
|
|
MX2021004928A
(es)
|
2018-10-31 |
2021-06-08 |
Merck Sharp & Dohme Llc |
Cristales de anticuerpo anti-pd-1 humano y metodos de uso de los mismos.
|
|
EP3876990A4
(en)
|
2018-11-07 |
2023-09-06 |
Merck Sharp & Dohme LLC |
CO-FORMULATIONS OF ANTI-LAG3 ANTIBODIES AND ANTI-PD-1 ANTIBODIES
|
|
KR20210108978A
(ko)
*
|
2018-12-21 |
2021-09-03 |
오제 이뮈노테라프틱스 |
이작용성 항-pd-1/il-7 분자
|
|
WO2020127369A1
(en)
*
|
2018-12-21 |
2020-06-25 |
Ose Immunotherapeutics |
Bifunctional molecule directed against human pd-1
|
|
CN111423512B
(zh)
*
|
2019-01-10 |
2024-01-05 |
北京比洋生物技术有限公司 |
阻断血管内皮细胞生长且活化t细胞的多靶向融合蛋白和包含其的药物组合物
|
|
CN111454364B
(zh)
*
|
2019-03-04 |
2021-03-02 |
北京天广实生物技术股份有限公司 |
结合cd40的抗体及其用途
|
|
CN111763261B
(zh)
*
|
2019-04-02 |
2022-08-09 |
杭州尚健生物技术有限公司 |
一种融合蛋白及其用途
|
|
WO2020243570A1
(en)
|
2019-05-30 |
2020-12-03 |
Bristol-Myers Squibb Company |
Cell localization signature and combination therapy
|
|
KR20220016155A
(ko)
|
2019-05-30 |
2022-02-08 |
브리스톨-마이어스 스큅 컴퍼니 |
면역-종양학 (i-o) 요법에 적합한 대상체를 확인하는 방법
|
|
US20220363760A1
(en)
|
2019-05-30 |
2022-11-17 |
Bristol-Myers Squibb Company |
Multi-tumor gene signature for suitability to immuno-oncology therapy
|
|
CN112079925B
(zh)
*
|
2019-06-13 |
2025-04-25 |
上海健信生物医药科技有限公司 |
靶向lag-3的抗体和双特异性抗体及其用途
|
|
WO2021024020A1
(en)
|
2019-08-06 |
2021-02-11 |
Astellas Pharma Inc. |
Combination therapy involving antibodies against claudin 18.2 and immune checkpoint inhibitors for treatment of cancer
|
|
WO2021055994A1
(en)
|
2019-09-22 |
2021-03-25 |
Bristol-Myers Squibb Company |
Quantitative spatial profiling for lag-3 antagonist therapy
|
|
WO2021092220A1
(en)
|
2019-11-06 |
2021-05-14 |
Bristol-Myers Squibb Company |
Methods of identifying a subject with a tumor suitable for a checkpoint inhibitor therapy
|
|
WO2021092221A1
(en)
|
2019-11-06 |
2021-05-14 |
Bristol-Myers Squibb Company |
Methods of identifying a subject with a tumor suitable for a checkpoint inhibitor therapy
|
|
CN115038718B
(zh)
*
|
2019-11-08 |
2024-07-02 |
山东先声生物制药有限公司 |
抗人程序性死亡配体-1(pd-l1)的抗体及其用途
|
|
US20220411499A1
(en)
|
2019-11-08 |
2022-12-29 |
Bristol-Myers Squibb Company |
LAG-3 Antagonist Therapy for Melanoma
|
|
JP2023514152A
(ja)
|
2020-02-06 |
2023-04-05 |
ブリストル-マイヤーズ スクイブ カンパニー |
Il-10およびその使用
|
|
CN111533782A
(zh)
*
|
2020-05-08 |
2020-08-14 |
中国药科大学 |
一种靶向免疫检查点lag-3的活性多肽及其应用
|
|
CA3185657A1
(en)
*
|
2020-06-04 |
2021-12-09 |
Leidos, Inc. |
Immunomodulatory compounds
|
|
KR20230035576A
(ko)
|
2020-07-07 |
2023-03-14 |
비온테크 에스이 |
Hpv 양성 암 치료용 rna
|
|
IL300813A
(en)
|
2020-08-28 |
2023-04-01 |
Bristol Myers Squibb Co |
LAG-3 antagonist therapy for hepatocellular carcinoma
|
|
AU2021334361A1
(en)
|
2020-08-31 |
2023-05-11 |
Bristol-Myers Squibb Company |
Cell localization signature and immunotherapy
|
|
KR20230093282A
(ko)
|
2020-10-23 |
2023-06-27 |
브리스톨-마이어스 스큅 컴퍼니 |
폐암에 대한 lag-3 길항제 요법
|
|
WO2022120179A1
(en)
|
2020-12-03 |
2022-06-09 |
Bristol-Myers Squibb Company |
Multi-tumor gene signatures and uses thereof
|
|
WO2022135667A1
(en)
|
2020-12-21 |
2022-06-30 |
BioNTech SE |
Therapeutic rna for treating cancer
|
|
WO2022135666A1
(en)
|
2020-12-21 |
2022-06-30 |
BioNTech SE |
Treatment schedule for cytokine proteins
|
|
TW202245808A
(zh)
|
2020-12-21 |
2022-12-01 |
德商拜恩迪克公司 |
用於治療癌症之治療性rna
|
|
JP2024501029A
(ja)
|
2020-12-28 |
2024-01-10 |
ブリストル-マイヤーズ スクイブ カンパニー |
Pd1/pd-l1抗体の皮下投与
|
|
US20220233693A1
(en)
|
2020-12-28 |
2022-07-28 |
Bristol-Myers Squibb Company |
Antibody Compositions and Methods of Use Thereof
|
|
US20240384350A1
(en)
|
2021-01-29 |
2024-11-21 |
Board Of Regents, The University Of Texas System |
Methods of treating cancer with kinase inhibitors
|
|
CN112500489B
(zh)
*
|
2021-02-07 |
2021-05-04 |
天津一瑞生物科技股份有限公司 |
一种抗oxa-23型碳青霉烯酶杂交瘤细胞株,单克隆抗体及应用
|
|
CN117858719A
(zh)
|
2021-03-29 |
2024-04-09 |
朱诺治疗学股份有限公司 |
使用检查点抑制剂疗法和car t细胞疗法的组合进行给药和治疗的方法
|
|
EP4319755A4
(en)
|
2021-04-08 |
2025-03-26 |
Board of Regents, The University of Texas System |
Compounds and methods for theranostic targeting of parp activity
|
|
EP4337694A1
(en)
|
2021-05-12 |
2024-03-20 |
Dana-Farber Cancer Institute, Inc. |
Lag3 and gal3 inhibitory agents, xbp1, cs1, and cd138 peptides, and methods of use thereof
|
|
CA3225254A1
(en)
|
2021-07-13 |
2023-01-19 |
BioNTech SE |
Multispecific binding agents against cd40 and cd137 in combination therapy for cancer
|
|
TW202333802A
(zh)
|
2021-10-11 |
2023-09-01 |
德商拜恩迪克公司 |
用於肺癌之治療性rna(二)
|
|
CA3224890A1
(en)
|
2021-10-29 |
2023-05-04 |
Bristol-Myers Squibb Company |
Lag-3 antagonist therapy for hematological cancer
|
|
KR20240135661A
(ko)
|
2022-01-26 |
2024-09-11 |
브리스톨-마이어스 스큅 컴퍼니 |
간세포성 암종에 대한 조합 요법
|
|
WO2023164638A1
(en)
|
2022-02-25 |
2023-08-31 |
Bristol-Myers Squibb Company |
Combination therapy for colorectal carcinoma
|
|
WO2023168404A1
(en)
|
2022-03-04 |
2023-09-07 |
Bristol-Myers Squibb Company |
Methods of treating a tumor
|
|
JP2025508076A
(ja)
|
2022-03-08 |
2025-03-21 |
アレンティス・セラピューティクス・アクチェンゲゼルシャフト |
T細胞の利用能を向上させるための抗クローディン-1抗体の使用
|
|
WO2023178329A1
(en)
|
2022-03-18 |
2023-09-21 |
Bristol-Myers Squibb Company |
Methods of isolating polypeptides
|
|
KR20250022071A
(ko)
|
2022-06-02 |
2025-02-14 |
브리스톨-마이어스 스큅 컴퍼니 |
항체 조성물 및 이의 이용 방법
|
|
JPWO2024111633A1
(https=)
*
|
2022-11-24 |
2024-05-30 |
|
|
|
EP4626552A1
(en)
|
2022-12-01 |
2025-10-08 |
MedImmune Limited |
Combination therapy for treatment of cancer comprising anti-pd-l1 and anti-cd73 antibodies
|
|
JP2026501506A
(ja)
|
2022-12-14 |
2026-01-16 |
アステラス・ファーマ・ヨーロッパ・ベスローデン・フェンノートシャップ |
Cldn18.2及びcd3に結合する二重特異性結合剤並びに免疫チェックポイント阻害剤を含む併用療法
|
|
EP4638503A1
(en)
|
2022-12-21 |
2025-10-29 |
Bristol-Myers Squibb Company |
Combination therapy for lung cancer
|
|
CN115960269B
(zh)
*
|
2023-01-30 |
2026-04-03 |
上海甲贝医药科技有限公司 |
一种重组长效人cxcr4&pd-1双靶点抗体融合蛋白及其制备方法
|
|
WO2024196952A1
(en)
|
2023-03-20 |
2024-09-26 |
Bristol-Myers Squibb Company |
Tumor subtype assessment for cancer therapy
|
|
WO2025038763A1
(en)
|
2023-08-15 |
2025-02-20 |
Bristol-Myers Squibb Company |
Ceramic hydroxyapatite chromatography flow through method
|
|
WO2025120866A1
(en)
|
2023-12-08 |
2025-06-12 |
Astellas Pharma Inc. |
Combination therapy involving bispecific binding agents binding to cldn18.2 and cd3 and agents stabilizing or increasing expression of cldn18.2
|
|
WO2026033885A1
(en)
|
2024-08-08 |
2026-02-12 |
Astellas Pharma Inc. |
Combination therapy involving bispecific binding agents binding to cldn18.2 and cd3 and agents stabilizing or increasing expression of cldn18.2
|
|
TW202541837A
(zh)
|
2023-12-08 |
2025-11-01 |
日商安斯泰來製藥公司 |
含有結合至cldn18.2和cd3之雙特異性結合劑和穩定或增加cldn18.2表現之藥劑之組合療法
|
|
WO2025120867A1
(en)
|
2023-12-08 |
2025-06-12 |
Astellas Pharma Inc. |
Combination therapy involving bispecific binding agents binding to cldn18.2 and cd3 and anti-vegfr2 antibodies
|
|
WO2025145207A1
(en)
|
2023-12-29 |
2025-07-03 |
Bristol-Myers Squibb Company |
Combination therapy of kras inhibitor and treg-depleting agent
|
|
WO2025184208A1
(en)
|
2024-02-27 |
2025-09-04 |
Bristol-Myers Squibb Company |
Anti-ceacam5 antibodies and uses thereof
|
|
US12521446B2
(en)
|
2024-02-27 |
2026-01-13 |
Bristol-Myers Squibb Company |
Anti-CEACAM5 antibody drug conjugates
|
|
WO2025245489A1
(en)
|
2024-05-24 |
2025-11-27 |
Bristol-Myers Squibb Company |
Treatment of tumors in subjects having fgl-1 positive samples
|