|
UA67760C2
(uk)
*
|
1997-12-11 |
2004-07-15 |
Міннесота Майнінг Енд Мануфакчурінг Компані |
Імідазонафтиридин та тетрагідроімідазонафтиридин, фармацевтична композиція, спосіб індукування біосинтезу цитокінів та спосіб лікування вірусної інфекції, проміжні сполуки
|
|
WO2000061151A2
(en)
*
|
1999-04-12 |
2000-10-19 |
The Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services |
Oligodeoxynucleotide and its use to induce an immune response
|
|
US6977245B2
(en)
*
|
1999-04-12 |
2005-12-20 |
The United States Of America As Represented By The Department Of Health And Human Services |
Oligodeoxynucleotide and its use to induce an immune response
|
|
US6331539B1
(en)
*
|
1999-06-10 |
2001-12-18 |
3M Innovative Properties Company |
Sulfonamide and sulfamide substituted imidazoquinolines
|
|
US6756382B2
(en)
*
|
1999-06-10 |
2004-06-29 |
3M Innovative Properties Company |
Amide substituted imidazoquinolines
|
|
US20030129251A1
(en)
*
|
2000-03-10 |
2003-07-10 |
Gary Van Nest |
Biodegradable immunomodulatory formulations and methods for use thereof
|
|
US6660735B2
(en)
*
|
2000-12-08 |
2003-12-09 |
3M Innovative Properties Company |
Urea substituted imidazoquinoline ethers
|
|
US6545016B1
(en)
|
2000-12-08 |
2003-04-08 |
3M Innovative Properties Company |
Amide substituted imidazopyridines
|
|
US6667312B2
(en)
*
|
2000-12-08 |
2003-12-23 |
3M Innovative Properties Company |
Thioether substituted imidazoquinolines
|
|
UA75622C2
(en)
|
2000-12-08 |
2006-05-15 |
3M Innovative Properties Co |
Aryl ether substituted imidazoquinolines, pharmaceutical composition based thereon
|
|
AU2006216669A1
(en)
*
|
2000-12-08 |
2006-08-31 |
3M Innovative Properties Company |
Compositions and methods for targeted delivery of immune response modifiers
|
|
US6664264B2
(en)
*
|
2000-12-08 |
2003-12-16 |
3M Innovative Properties Company |
Thioether substituted imidazoquinolines
|
|
US6664265B2
(en)
|
2000-12-08 |
2003-12-16 |
3M Innovative Properties Company |
Amido ether substituted imidazoquinolines
|
|
US6677349B1
(en)
*
|
2001-12-21 |
2004-01-13 |
3M Innovative Properties Company |
Sulfonamide and sulfamide substituted imidazoquinolines
|
|
EP1478327B1
(en)
*
|
2002-02-22 |
2015-04-29 |
Meda AB |
Method of reducing and treating uvb-induced immunosuppression
|
|
CA2488801A1
(en)
|
2002-06-07 |
2003-12-18 |
3M Innovative Properties Company |
Ether substituted imidazopyridines
|
|
NZ540826A
(en)
|
2002-12-20 |
2008-07-31 |
3M Innovative Properties Co |
Aryl / hetaryl substituted imidazoquinolines
|
|
EP1613956A2
(en)
*
|
2003-03-25 |
2006-01-11 |
3M Innovative Properties Company |
Selective activation of cellular activities mediated through a common toll-like receptor
|
|
US20040265351A1
(en)
*
|
2003-04-10 |
2004-12-30 |
Miller Richard L. |
Methods and compositions for enhancing immune response
|
|
US6943255B2
(en)
*
|
2003-06-06 |
2005-09-13 |
3M Innovative Properties Company |
Process for imidazo[4,5-c]pyridin-4-amines
|
|
WO2004110992A2
(en)
*
|
2003-06-06 |
2004-12-23 |
3M Innovative Properties Company |
Process for imidazo[4,5-c] pyridin-4-amines
|
|
AU2004264336B2
(en)
*
|
2003-08-05 |
2010-12-23 |
3M Innovative Properties Company |
Formulations containing an immune response modifier
|
|
AU2004266641A1
(en)
|
2003-08-12 |
2005-03-03 |
3M Innovative Properties Company |
Oxime substituted imidazo-containing compounds
|
|
WO2005018555A2
(en)
*
|
2003-08-14 |
2005-03-03 |
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Lipid-modified immune response modifiers
|
|
CA2551075A1
(en)
*
|
2003-08-25 |
2005-03-03 |
3M Innovative Properties Company |
Immunostimulatory combinations and treatments
|
|
CA2536249A1
(en)
*
|
2003-08-25 |
2005-03-10 |
3M Innovative Properties Company |
Delivery of immune response modifier compounds
|
|
EP1658076B1
(en)
|
2003-08-27 |
2013-03-06 |
3M Innovative Properties Company |
Aryloxy and arylalkyleneoxy substituted imidazoquinolines
|
|
US20050054665A1
(en)
|
2003-09-05 |
2005-03-10 |
3M Innovative Properties Company |
Treatment for CD5+ B cell lymphoma
|
|
ES2544477T3
(es)
|
2003-10-03 |
2015-08-31 |
3M Innovative Properties Company |
Imidazoquinolinas sustituidas con alcoxi
|
|
KR20060120069A
(ko)
|
2003-10-03 |
2006-11-24 |
쓰리엠 이노베이티브 프로퍼티즈 컴파니 |
피라졸로피리딘 및 그의 유사체
|
|
US7544697B2
(en)
*
|
2003-10-03 |
2009-06-09 |
Coley Pharmaceutical Group, Inc. |
Pyrazolopyridines and analogs thereof
|
|
JP2007509987A
(ja)
*
|
2003-10-31 |
2007-04-19 |
スリーエム イノベイティブ プロパティズ カンパニー |
免疫応答調節剤化合物による好中球活性化
|
|
JP2007511535A
(ja)
|
2003-11-14 |
2007-05-10 |
スリーエム イノベイティブ プロパティズ カンパニー |
ヒドロキシルアミン置換イミダゾ環化合物
|
|
US7897767B2
(en)
|
2003-11-14 |
2011-03-01 |
3M Innovative Properties Company |
Oxime substituted imidazoquinolines
|
|
CA2547085A1
(en)
*
|
2003-11-25 |
2005-06-09 |
3M Innovative Properties Company |
Hydroxylamine and oxime substituted imidazoquinolines, imidazopyridines, and imidazonaphthyridines
|
|
RU2409576C2
(ru)
|
2003-11-25 |
2011-01-20 |
3М Инновейтив Пропертиз Компани |
Системы, содержащие имидазольное кольцо с заместителями, и способы их получения
|
|
US8940755B2
(en)
*
|
2003-12-02 |
2015-01-27 |
3M Innovative Properties Company |
Therapeutic combinations and methods including IRM compounds
|
|
US20050226878A1
(en)
*
|
2003-12-02 |
2005-10-13 |
3M Innovative Properties Company |
Therapeutic combinations and methods including IRM compounds
|
|
CA2549216A1
(en)
*
|
2003-12-04 |
2005-08-25 |
3M Innovative Properties Company |
Sulfone substituted imidazo ring ethers
|
|
FR2863890B1
(fr)
*
|
2003-12-19 |
2006-03-24 |
Aventis Pasteur |
Composition immunostimulante
|
|
WO2005066170A1
(en)
|
2003-12-29 |
2005-07-21 |
3M Innovative Properties Company |
Arylalkenyl and arylalkynyl substituted imidazoquinolines
|
|
EP1699792A1
(en)
*
|
2003-12-29 |
2006-09-13 |
3M Innovative Properties Company |
Piperazine, 1,4¨diazepane, 1,4¨diazocane, and 1,5¨diazocane fused imidazo ring compounds
|
|
CA2551399A1
(en)
|
2003-12-30 |
2005-07-21 |
3M Innovative Properties Company |
Imidazoquinolinyl, imidazopyridinyl, and imidazonaphthyridinyl sulfonamides
|
|
US20050239735A1
(en)
*
|
2003-12-30 |
2005-10-27 |
3M Innovative Properties Company |
Enhancement of immune responses
|
|
EP1730143A2
(en)
|
2004-03-24 |
2006-12-13 |
3M Innovative Properties Company |
Amide substituted imidazopyridines, imidazoquinolines, and imidazonaphthyridines
|
|
EP1735010A4
(en)
*
|
2004-04-09 |
2008-08-27 |
3M Innovative Properties Co |
METHODS, COMPOSITIONS AND PREPARATIONS FOR ADMINISTRATION OF IMMUNE RESPONSE MODIFIERS (MRI)
|
|
JP2008505857A
(ja)
*
|
2004-04-28 |
2008-02-28 |
スリーエム イノベイティブ プロパティズ カンパニー |
粘膜ワクチン接種のための組成物および方法
|
|
US20050267145A1
(en)
*
|
2004-05-28 |
2005-12-01 |
Merrill Bryon A |
Treatment for lung cancer
|
|
WO2005123079A2
(en)
*
|
2004-06-14 |
2005-12-29 |
3M Innovative Properties Company |
Urea substituted imidazopyridines, imidazoquinolines, and imidazonaphthyridines
|
|
WO2005123080A2
(en)
|
2004-06-15 |
2005-12-29 |
3M Innovative Properties Company |
Nitrogen-containing heterocyclyl substituted imidazoquinolines and imidazonaphthyridines
|
|
WO2006065280A2
(en)
|
2004-06-18 |
2006-06-22 |
3M Innovative Properties Company |
Isoxazole, dihydroisoxazole, and oxadiazole substituted imidazo ring compounds and methods
|
|
US20070259881A1
(en)
*
|
2004-06-18 |
2007-11-08 |
Dellaria Joseph F Jr |
Substituted Imidazo Ring Systems and Methods
|
|
WO2006009826A1
(en)
|
2004-06-18 |
2006-01-26 |
3M Innovative Properties Company |
Aryloxy and arylalkyleneoxy substituted thiazoloquinolines and thiazolonaphthyridines
|
|
US8541438B2
(en)
|
2004-06-18 |
2013-09-24 |
3M Innovative Properties Company |
Substituted imidazoquinolines, imidazopyridines, and imidazonaphthyridines
|
|
WO2006038923A2
(en)
|
2004-06-18 |
2006-04-13 |
3M Innovative Properties Company |
Aryl substituted imidazonaphthyridines
|
|
US7884207B2
(en)
*
|
2004-06-18 |
2011-02-08 |
3M Innovative Properties Company |
Substituted imidazoquinolines, imidazopyridines, and imidazonaphthyridines
|
|
US20060045885A1
(en)
*
|
2004-08-27 |
2006-03-02 |
Kedl Ross M |
Method of eliciting an immune response against HIV
|
|
US20060045886A1
(en)
*
|
2004-08-27 |
2006-03-02 |
Kedl Ross M |
HIV immunostimulatory compositions
|
|
PL1789042T3
(pl)
*
|
2004-09-02 |
2012-09-28 |
3M Innovative Properties Co |
Układy pierścieni 1-alkoksy 1H-imidazo i sposoby
|
|
CA2578975A1
(en)
|
2004-09-02 |
2006-03-16 |
3M Innovative Properties Company |
2-amino 1h imidazo ring systems and methods
|
|
US20070243215A1
(en)
*
|
2004-10-08 |
2007-10-18 |
Miller Richard L |
Adjuvant for Dna Vaccines
|
|
US9492400B2
(en)
|
2004-11-04 |
2016-11-15 |
Massachusetts Institute Of Technology |
Coated controlled release polymer particles as efficient oral delivery vehicles for biopharmaceuticals
|
|
EP1819364A4
(en)
*
|
2004-12-08 |
2010-12-29 |
3M Innovative Properties Co |
COMPOSITIONS, IMMUNOMODULATORY COMBINATIONS AND ASSOCIATED METHODS
|
|
EP1819226A4
(en)
*
|
2004-12-08 |
2010-12-29 |
3M Innovative Properties Co |
COMBINATIONS AND METHODS OF IMMUNOSTIMULATION
|
|
US8461174B2
(en)
*
|
2004-12-30 |
2013-06-11 |
3M Innovative Properties Company |
Treatment for cutaneous metastases
|
|
AU2005326708C1
(en)
|
2004-12-30 |
2012-08-30 |
3M Innovative Properties Company |
Substituted chiral fused [1,2]imidazo[4,5-c] ring compounds
|
|
CA2592904C
(en)
|
2004-12-30 |
2015-04-07 |
3M Innovative Properties Company |
Chiral fused [1,2]imidazo[4,5-c] ring compounds
|
|
US8436176B2
(en)
*
|
2004-12-30 |
2013-05-07 |
Medicis Pharmaceutical Corporation |
Process for preparing 2-methyl-1-(2-methylpropyl)-1H-imidazo[4,5-c][1,5]naphthyridin-4-amine
|
|
NZ556399A
(en)
*
|
2004-12-30 |
2009-03-31 |
Takeda Pharmaceutical |
1-(2-methylpropyl)-1H-imidazo[4,5-C][1,5]naphthyridin-4-amine ethanesulfonate and 1-(2-methylpropyl)-1H-imidazo[4,5-C][1,5]naphthyridin-4-amine methanesulfonate
|
|
CN107261127A
(zh)
*
|
2005-01-28 |
2017-10-20 |
盖伦生物公司 |
免疫活性组合物
|
|
US9248127B2
(en)
|
2005-02-04 |
2016-02-02 |
3M Innovative Properties Company |
Aqueous gel formulations containing immune response modifiers
|
|
WO2006086449A2
(en)
|
2005-02-09 |
2006-08-17 |
Coley Pharmaceutical Group, Inc. |
Alkyloxy substituted thiazoloquinolines and thiazolonaphthyridines
|
|
JP2008530252A
(ja)
|
2005-02-09 |
2008-08-07 |
コーリー ファーマシューティカル グループ,インコーポレイテッド |
オキシムおよびヒドロキシルアミンで置換されたチアゾロ[4,5−c]環化合物ならびに方法
|
|
WO2006091394A2
(en)
|
2005-02-11 |
2006-08-31 |
Coley Pharmaceutical Group, Inc. |
Substituted imidazoquinolines and imidazonaphthyridines
|
|
WO2006086634A2
(en)
|
2005-02-11 |
2006-08-17 |
Coley Pharmaceutical Group, Inc. |
Oxime and hydroxylamine substituted imidazo[4,5-c] ring compounds and methods
|
|
EP1851218A2
(en)
|
2005-02-23 |
2007-11-07 |
3M Innovative Properties Company |
Hydroxyalkyl substituted imidazoquinoline compounds and methods
|
|
WO2006098852A2
(en)
|
2005-02-23 |
2006-09-21 |
Coley Pharmaceutical Group, Inc. |
Hydroxyalkyl substituted imidazoquinolines
|
|
JP2008538203A
(ja)
|
2005-02-23 |
2008-10-16 |
コーリー ファーマシューティカル グループ,インコーポレイテッド |
インターフェロンの生合成を優先的に誘導する方法
|
|
EP1851220A2
(en)
|
2005-02-23 |
2007-11-07 |
3M Innovative Properties Company |
Hydroxyalkyl substituted imidazonaphthyridines
|
|
AU2006223148A1
(en)
|
2005-03-14 |
2006-09-21 |
3M Innovative Properties Company |
Method of treating actinic keratosis
|
|
AU2006232375A1
(en)
|
2005-04-01 |
2006-10-12 |
Coley Pharmaceutical Group, Inc. |
1-substituted pyrazolo (3,4-c) ring compounds as modulators of cytokine biosynthesis for the treatment of viral infections and neoplastic diseases
|
|
US7943610B2
(en)
|
2005-04-01 |
2011-05-17 |
3M Innovative Properties Company |
Pyrazolopyridine-1,4-diamines and analogs thereof
|
|
JP2008539252A
(ja)
*
|
2005-04-25 |
2008-11-13 |
スリーエム イノベイティブ プロパティズ カンパニー |
免疫活性化組成物
|
|
CA2621083C
(en)
*
|
2005-08-30 |
2017-04-11 |
University Of Miami |
Immunomodulating tumor necrosis factor receptor 25 (tnfr25) agonists, antagonists and immunotoxins
|
|
EA200800782A1
(ru)
|
2005-09-09 |
2008-08-29 |
Коли Фармасьютикал Груп, Инк. |
ПРОИЗВОДНЫЕ АМИДА И КАРБАМАТА N-{2-[4-АМИНО-2-(ЭТОКСИМЕТИЛ)-1Н-ИМИДАЗОЛО[4,5-c]ХИНОЛИН-1-IL]-1,1-ДИМЕТИЛЭТИЛ}МЕТАНСУЛЬФОНАМИДА И СПОСОБЫ
|
|
ZA200803029B
(en)
*
|
2005-09-09 |
2009-02-25 |
Coley Pharm Group Inc |
Amide and carbamate derivatives of alkyl substituted /V-[4-(4-amino-1H-imidazo[4,5-c] quinolin-1-yl)butyl] methane-sulfonamides and methods
|
|
US20080233105A1
(en)
*
|
2005-09-13 |
2008-09-25 |
Green William R |
Compositions and methods for preventing or treating a viral infection
|
|
GB0519303D0
(en)
*
|
2005-09-21 |
2005-11-02 |
Oxford Biomedica Ltd |
Chemo-immunotherapy method
|
|
DE602006014720D1
(de)
*
|
2005-10-07 |
2010-07-15 |
Proyecto Biomedicina Cima Sl |
Immunstimulatorische kombination zur vorbeugung und behandlung von hepatitis c
|
|
ES2334472B1
(es)
*
|
2006-06-09 |
2011-01-21 |
Proyecto De Biomedicina Cima, S.L. |
Combinacion inmunoestimuladora para profilaxis y tratamiento de hepatitis c.
|
|
WO2007056112A2
(en)
|
2005-11-04 |
2007-05-18 |
Coley Pharmaceutical Group, Inc. |
Hydroxy and alkoxy substituted 1h-imidazoquinolines and methods
|
|
US20090196877A1
(en)
*
|
2005-12-02 |
2009-08-06 |
The Johns Hopkins University |
Novel Method to Increase Memory T Lymphocytes and Enhance Their Functions
|
|
US9267937B2
(en)
|
2005-12-15 |
2016-02-23 |
Massachusetts Institute Of Technology |
System for screening particles
|
|
WO2007079146A1
(en)
*
|
2005-12-28 |
2007-07-12 |
Coley Pharmaceutical Group, Inc |
Treatment for non-hodgkin's lymphoma
|
|
WO2007079169A2
(en)
*
|
2005-12-28 |
2007-07-12 |
Coley Pharmaceutical Group, Inc. |
Treatment for acute myeloid leukemia
|
|
WO2007079203A2
(en)
*
|
2005-12-28 |
2007-07-12 |
3M Innovative Properties Company |
Treatment for cutaneous t cell lymphoma
|
|
WO2007079202A2
(en)
*
|
2005-12-28 |
2007-07-12 |
Coley Pharmaceutical Group, Inc. |
Treatment for acute lymhoblastic leukemia
|
|
WO2007079171A2
(en)
*
|
2005-12-28 |
2007-07-12 |
Coley Pharmaceutical Group, Inc. |
Treatment for hodgkin's lymphoma
|
|
WO2007120368A2
(en)
*
|
2006-01-09 |
2007-10-25 |
The Regents Of The University Of California |
Immunostimulatory combinations for vaccine adjuvants
|
|
CA2638865A1
(en)
*
|
2006-02-13 |
2007-10-18 |
Genentech, Inc. |
Methods and compositions for targeting relt
|
|
WO2007100634A2
(en)
|
2006-02-22 |
2007-09-07 |
3M Innovative Properties Company |
Immune response modifier conjugates
|
|
WO2007103048A2
(en)
*
|
2006-03-01 |
2007-09-13 |
Regents Of The University Of Colorado |
Tlr agonist (flagellin)/cd40 agonist/antigen protein and dna conjugates and use thereof for inducing synergistic enhancement in immunity
|
|
US8329721B2
(en)
|
2006-03-15 |
2012-12-11 |
3M Innovative Properties Company |
Hydroxy and alkoxy substituted 1H-imidazonaphthyridines and methods
|
|
WO2008105773A2
(en)
|
2006-03-31 |
2008-09-04 |
Massachusetts Institute Of Technology |
System for targeted delivery of therapeutic agents
|
|
WO2007122392A1
(en)
*
|
2006-04-20 |
2007-11-01 |
King's College London |
Composition comprising a cytotoxic t-cell - inducing adjuvant
|
|
JP5427027B2
(ja)
*
|
2006-05-03 |
2014-02-26 |
ザ・リージェンツ・オブ・ザ・ユニバーシティ・オブ・コロラド,ア・ボディー・コーポレイト |
Cd40アゴニスト抗体/i型インターフェロン相乗性アジュバントの結合体、それを含む複合体、および細胞性免疫を強化する治療としてのその使用
|
|
CA2652599C
(en)
*
|
2006-05-03 |
2019-09-24 |
Ross Kedl |
Cd40 agonist antibody/type1 interferon synergistic adjuvant combination, conjugates containing and use thereof as a therapeutic to enhance cellular immunity
|
|
JP5630998B2
(ja)
|
2006-05-15 |
2014-11-26 |
マサチューセッツ インスティテュート オブ テクノロジー |
機能的粒子のためのポリマー
|
|
WO2007150030A2
(en)
*
|
2006-06-23 |
2007-12-27 |
Massachusetts Institute Of Technology |
Microfluidic synthesis of organic nanoparticles
|
|
US7906506B2
(en)
|
2006-07-12 |
2011-03-15 |
3M Innovative Properties Company |
Substituted chiral fused [1,2] imidazo [4,5-c] ring compounds and methods
|
|
US20100144845A1
(en)
*
|
2006-08-04 |
2010-06-10 |
Massachusetts Institute Of Technology |
Oligonucleotide systems for targeted intracellular delivery
|
|
WO2008030511A2
(en)
|
2006-09-06 |
2008-03-13 |
Coley Pharmaceuticial Group, Inc. |
Substituted 3,4,6,7-tetrahydro-5h, 1,2a,4a,8-tetraazacyclopenta[cd]phenalenes
|
|
US20090074711A1
(en)
*
|
2006-09-07 |
2009-03-19 |
University Of Southhampton |
Human therapies using chimeric agonistic anti-human cd40 antibody
|
|
GB0620894D0
(en)
|
2006-10-20 |
2006-11-29 |
Univ Southampton |
Human immune therapies using a CD27 agonist alone or in combination with other immune modulators
|
|
US20080149123A1
(en)
*
|
2006-12-22 |
2008-06-26 |
Mckay William D |
Particulate material dispensing hairbrush with combination bristles
|
|
US9217129B2
(en)
|
2007-02-09 |
2015-12-22 |
Massachusetts Institute Of Technology |
Oscillating cell culture bioreactor
|
|
WO2008124639A2
(en)
*
|
2007-04-04 |
2008-10-16 |
Massachusetts Institute Of Technology |
Poly (amino acid) targeting moieties
|
|
WO2008133983A1
(en)
|
2007-04-25 |
2008-11-06 |
Immurx, Inc. |
Adjuvant combinations of nkt activator, cd40 agonist, and optional antigen, the use through inducing synergistic cellular immunity
|
|
MX2009013779A
(es)
*
|
2007-06-15 |
2010-05-20 |
Immurx Inc |
Uso de agonistas de tlr y/o interferonas tipo 1 para aliviar la toxicidad de los regimenes terapeuticos de agonistas de tnf-r.
|
|
WO2009006680A1
(en)
*
|
2007-07-06 |
2009-01-15 |
Sydney West Area Health Service |
Epitopes of herpes simplex virus
|
|
WO2009046313A2
(en)
*
|
2007-10-05 |
2009-04-09 |
University Of Maryland, Baltimore |
Novel compositions and methods for stimulating erythropoiesis in a mammal
|
|
BRPI0817664A2
(pt)
|
2007-10-12 |
2015-03-24 |
Massachusetts Inst Technology |
Nanopartículas, método para preparar nanopartículas e método para tratar terapeuticamente ou profilaticamente um indivíduo
|
|
KR100900837B1
(ko)
*
|
2007-12-07 |
2009-06-04 |
(주)두비엘 |
리포펩타이드와 폴리(i:c)를 아쥬반트로 포함하는 강력한백신 조성물
|
|
WO2009099643A1
(en)
*
|
2008-02-07 |
2009-08-13 |
The J. David Gladstone Institutes |
Use of sirt1 activators or inhibitors to modulate an immune response
|
|
US8343498B2
(en)
|
2008-10-12 |
2013-01-01 |
Massachusetts Institute Of Technology |
Adjuvant incorporation in immunonanotherapeutics
|
|
US8277812B2
(en)
|
2008-10-12 |
2012-10-02 |
Massachusetts Institute Of Technology |
Immunonanotherapeutics that provide IgG humoral response without T-cell antigen
|
|
US8343497B2
(en)
|
2008-10-12 |
2013-01-01 |
The Brigham And Women's Hospital, Inc. |
Targeting of antigen presenting cells with immunonanotherapeutics
|
|
US8591905B2
(en)
|
2008-10-12 |
2013-11-26 |
The Brigham And Women's Hospital, Inc. |
Nicotine immunonanotherapeutics
|
|
AU2009308707A1
(en)
*
|
2008-10-31 |
2010-05-06 |
Biogen Idec Ma Inc. |
LIGHT targeting molecules and uses thereof
|
|
CN102325790A
(zh)
|
2008-12-03 |
2012-01-18 |
西马生物医学计划公司 |
应用酚可溶性调控蛋白研制疫苗
|
|
CA2745096C
(en)
|
2008-12-09 |
2013-11-05 |
Coley Pharmaceutical Group, Inc. |
Immunostimulatory oligonucleotides
|
|
US8552165B2
(en)
*
|
2008-12-09 |
2013-10-08 |
Heather Davis |
Immunostimulatory oligonucleotides
|
|
MX2011010050A
(es)
|
2009-03-25 |
2011-12-14 |
Univ Texas |
Composiciones para estimulación de resistencia inmune innata de mamiferos a patógenos.
|
|
US9402917B2
(en)
|
2009-04-03 |
2016-08-02 |
Duke University |
Methods for the induction of broadly anti-HIV-1 neutralizing antibody responses employing liposome-MPER peptide compositions
|
|
DE102009034779A1
(de)
|
2009-07-25 |
2011-02-03 |
Emc Microcollections Gmbh |
Synthetische Analoga bakterieller Lipopeptide und ihre Anwendung zur Therapie und Prophylaxe allergischer Erkrankungen
|
|
WO2011072871A1
(en)
|
2009-12-18 |
2011-06-23 |
Bavarian Nordic A/S |
Production of ifn-lambda by conventional dendritic cells and uses thereof
|
|
US10238734B2
(en)
|
2010-03-23 |
2019-03-26 |
The Regents Of The University Of California |
Compositions and methods for self-adjuvanting vaccines against microbes and tumors
|
|
WO2011133867A2
(en)
|
2010-04-23 |
2011-10-27 |
The Regents Of The University Of Colorado, A Body Corporate |
Vaccines, methods of administering vaccines, methods and products for treating and/or delaying onset of dysplastic lesions, and wafers for oral administration
|
|
US20110274653A1
(en)
|
2010-05-07 |
2011-11-10 |
Baylor Research Institute |
Dendritic cell immunoreceptors (dcir)-mediated crosspriming of human cd8+ t cells
|
|
US20110293700A1
(en)
|
2010-05-26 |
2011-12-01 |
Selecta Biosciences, Inc. |
Nanocarrier compositions with uncoupled adjuvant
|
|
NZ604040A
(en)
|
2010-06-03 |
2015-02-27 |
Pharmacyclics Inc |
The use of inhibitors of bruton’s tyrosine kinase (btk)
|
|
CA2804550C
(en)
|
2010-07-09 |
2021-01-05 |
Bionovion Holding B.V. |
Agonistic antibody to cd27
|
|
HRP20170433T1
(hr)
|
2010-08-17 |
2017-05-05 |
3M Innovative Properties Company |
Pripravci spoja za izmjenu lipidiranog imunološkog odgovora, formulacije, i postupci
|
|
EP2640190A4
(en)
|
2010-11-05 |
2016-05-11 |
Selecta Biosciences Inc |
MODIFIED NICOTINIC COMPOUNDS AND ASSOCIATED METHODS
|
|
WO2012065755A1
(en)
|
2010-11-19 |
2012-05-24 |
Bavarian Nordic A/S |
Production of ifn-lambda by b cells
|
|
JP2014506576A
(ja)
*
|
2011-02-10 |
2014-03-17 |
ユニバーシティー オブ ルーイビル リサーチ ファンデーション,インコーポレーテッド |
4−1bblを含むアジュバント組成物
|
|
DE102011018499A1
(de)
|
2011-04-23 |
2012-10-25 |
Emc Microcollections Gmbh |
Topische Nanopartikel-Vakzine zur Immunstimulation der dendritischen Zellen in der Haut
|
|
WO2012167081A1
(en)
|
2011-06-03 |
2012-12-06 |
3M Innovative Properties Company |
Hydrazino 1h-imidazoquinolin-4-amines and conjugates made therefrom
|
|
CN103582496B
(zh)
|
2011-06-03 |
2016-05-11 |
3M创新有限公司 |
具有聚乙二醇链段的异双官能连接基以及由其制成的免疫应答调节剂缀合物
|
|
CN109172819A
(zh)
|
2011-07-29 |
2019-01-11 |
西莱克塔生物科技公司 |
产生体液和细胞毒性t淋巴细胞(ctl)免疫应答的合成纳米载体
|
|
KR20150032340A
(ko)
|
2012-07-24 |
2015-03-25 |
파마시클릭스, 인코포레이티드 |
브루톤 티로신 키나제(btk)의 억제제에 대한 내성과 관련된 돌연변이
|
|
US20150238586A1
(en)
|
2012-08-15 |
2015-08-27 |
California Stem Cell, Inc. |
Rapid Method Production High Purity Cancer Stem Cells and Population of High Purity Cancer Stem Cells
|
|
EA201590822A1
(ru)
|
2012-11-02 |
2016-01-29 |
Фармасайкликс, Инк. |
Адъювантная терапия ингибитором киназы семейства tec
|
|
EP2950788B1
(en)
*
|
2013-02-04 |
2019-01-09 |
University Of Huddersfield |
Composition comprising a tnfr agonist and at least one thioredoxin inhibitor for use in the treatment of carcinoma.
|
|
WO2014157692A1
(ja)
|
2013-03-29 |
2014-10-02 |
大日本住友製薬株式会社 |
Wt1抗原ペプチドコンジュゲートワクチン
|
|
WO2015013673A1
(en)
|
2013-07-25 |
2015-01-29 |
Aurasense Therapeutics, Llc |
Spherical nucleic acid-based constructs as immunostimulatory agents for prophylactic and therapeutic use
|
|
CN105682683A
(zh)
|
2013-08-02 |
2016-06-15 |
阿杜罗生物科技控股有限公司 |
结合cd27激动剂以及免疫检查点抑制以用于免疫刺激
|
|
WO2015048635A1
(en)
|
2013-09-27 |
2015-04-02 |
Duke University |
Mper-liposome conjugates and uses thereof
|
|
CR20160214A
(es)
|
2013-11-05 |
2016-10-11 |
3M Innovative Properties Co |
Formulaciones de inyección con base en aceite de sésamo
|
|
ES2754239T3
(es)
|
2014-03-12 |
2020-04-16 |
Curevac Ag |
Combinación de vacunación y agonistas de OX40
|
|
JP2017509336A
(ja)
|
2014-03-20 |
2017-04-06 |
ファーマサイクリックス エルエルシー |
ホスホリパーゼcガンマ2及び耐性に関連した変異
|
|
US10434064B2
(en)
|
2014-06-04 |
2019-10-08 |
Exicure, Inc. |
Multivalent delivery of immune modulators by liposomal spherical nucleic acids for prophylactic or therapeutic applications
|
|
CN106604932B
(zh)
|
2014-07-10 |
2024-12-10 |
苏黎世大学 |
人白细胞介素-2的免疫刺激单克隆抗体
|
|
KR20170060042A
(ko)
|
2014-09-13 |
2017-05-31 |
노파르티스 아게 |
Alk 억제제의 조합 요법
|
|
WO2016044839A2
(en)
|
2014-09-19 |
2016-03-24 |
The Board Of Regents Of The University Of Texas System |
Compositions and methods for treating viral infections through stimulated innate immunity in combination with antiviral compounds
|
|
EA201790737A1
(ru)
|
2014-10-03 |
2017-08-31 |
Новартис Аг |
Комбинированная терапия
|
|
JP6423889B2
(ja)
|
2014-10-07 |
2018-11-14 |
サイトリミック株式会社 |
Hsp70由来のペプチド、これを用いた癌の治療又は予防のための医薬組成物、免疫誘導剤、及び抗原提示細胞の製造方法
|
|
MA41044A
(fr)
|
2014-10-08 |
2017-08-15 |
Novartis Ag |
Compositions et procédés d'utilisation pour une réponse immunitaire accrue et traitement contre le cancer
|
|
MX389663B
(es)
|
2014-10-14 |
2025-03-20 |
Novartis Ag |
Moleculas de anticuerpo que se unen a pd-l1 y usos de las mismas.
|
|
CA2968531A1
(en)
|
2014-11-21 |
2016-05-26 |
Northwestern University |
The sequence-specific cellular uptake of spherical nucleic acid nanoparticle conjugates
|
|
WO2016100882A1
(en)
|
2014-12-19 |
2016-06-23 |
Novartis Ag |
Combination therapies
|
|
EP3269733B1
(en)
|
2015-03-09 |
2020-06-17 |
Cytlimic Inc. |
Peptide derived from gpc3, pharmaceutical composition for treatment or prevention of cancer using same, immunity inducer, and method for producing antigen-presenting cells
|
|
US10449211B2
(en)
|
2015-03-10 |
2019-10-22 |
Aduro Biotech, Inc. |
Compositions and methods for activating “stimulator of interferon gene”—dependent signalling
|
|
US10842848B2
(en)
|
2015-04-07 |
2020-11-24 |
Cytlimic Inc. |
Method for treating cancer by adminstering poly I:C and LAG-3-IgG fusion protein
|
|
TWI716405B
(zh)
|
2015-05-07 |
2021-01-21 |
美商艾吉納斯公司 |
抗ox40抗體及其使用方法
|
|
EP3299028B1
(en)
*
|
2015-05-20 |
2024-10-30 |
Sumitomo Pharma Co., Ltd. |
Combination of wt1 antigen peptide, immunomodulator and wt1 helper peptide
|
|
CA2992298A1
(en)
|
2015-07-23 |
2017-01-26 |
Inhibrx Lp |
Multivalent and multispecific gitr-binding fusion proteins
|
|
DK3317301T3
(da)
|
2015-07-29 |
2021-06-28 |
Immutep Sas |
Kombinationsterapier omfattende antistofmolekyler mod lag-3
|
|
EP3878465A1
(en)
|
2015-07-29 |
2021-09-15 |
Novartis AG |
Combination therapies comprising antibody molecules to tim-3
|
|
US20180222982A1
(en)
|
2015-07-29 |
2018-08-09 |
Novartis Ag |
Combination therapies comprising antibody molecules to pd-1
|
|
TW201716084A
(zh)
*
|
2015-08-06 |
2017-05-16 |
葛蘭素史克智慧財產發展有限公司 |
組合物及其用途與治療
|
|
EP3383430A4
(en)
|
2015-12-02 |
2019-12-18 |
Agenus Inc. |
ANTIBODIES AND METHOD FOR USE THEREOF
|
|
EP3389712B1
(en)
|
2015-12-17 |
2024-04-10 |
Novartis AG |
Antibody molecules to pd-1 and uses thereof
|
|
BR112018014150A2
(en)
|
2016-01-11 |
2018-12-11 |
Novartis Ag |
immunostimulating humanized monoclonal antibodies to human interleukin-2, and fusion proteins thereof
|
|
KR102617833B1
(ko)
|
2016-05-06 |
2023-12-27 |
엑시큐어 오퍼레이팅 컴퍼니 |
인터류킨 17 수용체 mRNA의 특이적 녹다운을 위한 안티센스 올리고뉴클레오티드 (ASO)를 제시하는 리포좀성 구형 핵산 (SNA) 구축물
|
|
DE102016005550B4
(de)
|
2016-05-09 |
2024-09-26 |
Hans-Georg Rammensee |
Adjuvans zur lnduzierung einer zellulären lmmunantwort
|
|
US11098077B2
(en)
|
2016-07-05 |
2021-08-24 |
Chinook Therapeutics, Inc. |
Locked nucleic acid cyclic dinucleotide compounds and uses thereof
|
|
IL263616B2
(en)
|
2016-07-07 |
2025-01-01 |
Univ Leland Stanford Junior |
Antibody-adjuvant conjugates
|
|
WO2018039629A2
(en)
|
2016-08-25 |
2018-03-01 |
Northwestern University |
Micellar spherical nucleic acids from thermoresponsive, traceless templates
|
|
JOP20190055A1
(ar)
|
2016-09-26 |
2019-03-24 |
Merck Sharp & Dohme |
أجسام مضادة ضد cd27
|
|
EP3522935A4
(en)
*
|
2016-10-06 |
2020-05-13 |
EnGeneIC Molecular Delivery Pty Ltd. |
BACTERIAL MINICELLS FOR THE DELIVERY OF NUCLEIC ACID ADJUVANTS AND METHODS OF USE THEREOF
|
|
EP3527216B1
(en)
|
2016-10-11 |
2024-02-14 |
NEC Corporation |
A medicine comprising a toll-like receptor agonist, lag-3 protein, a hsp70-derived peptide and a gpc3-derived peptide
|
|
MA46770A
(fr)
|
2016-11-09 |
2019-09-18 |
Agenus Inc |
Anticorps anti-ox40, anticorps anti-gitr, et leurs procédés d'utilisation
|
|
EP3549957A4
(en)
|
2016-11-30 |
2020-08-05 |
Sumitomo Dainippon Pharma Co., Ltd. |
AUXILIARY PEPTIDE WT1, AND COMBINATION OF DUDIT PEPTIDE AND CONJUGATE PEPTIDE ANTIGENIC FOR CANCER
|
|
BR112019017241A2
(pt)
|
2017-04-13 |
2020-04-14 |
Agenus Inc |
anticorpos anti-cd137 e métodos de uso dos mesmos
|
|
UY37695A
(es)
|
2017-04-28 |
2018-11-30 |
Novartis Ag |
Compuesto dinucleótido cíclico bis 2’-5’-rr-(3’f-a)(3’f-a) y usos del mismo
|
|
US11696954B2
(en)
|
2017-04-28 |
2023-07-11 |
Exicure Operating Company |
Synthesis of spherical nucleic acids using lipophilic moieties
|
|
CN110582300B
(zh)
*
|
2017-05-02 |
2024-08-02 |
尼克塔治疗公司 |
肿瘤免疫治疗性治疗方法
|
|
WO2018209270A1
(en)
|
2017-05-11 |
2018-11-15 |
Northwestern University |
Adoptive cell therapy using spherical nucleic acids (snas)
|
|
WO2018223004A1
(en)
|
2017-06-01 |
2018-12-06 |
Xencor, Inc. |
Bispecific antibodies that bind cd20 and cd3
|
|
US20200181274A1
(en)
|
2017-06-01 |
2020-06-11 |
Novartis Ag |
Bispecific antibodies that bind cd 123 cd3
|
|
EP3652209A2
(en)
|
2017-07-11 |
2020-05-20 |
Compass Therapeutics LLC |
Agonist antibodies that bind human cd137 and uses thereof
|
|
EP4257198A3
(en)
|
2017-08-22 |
2023-10-18 |
Dynavax Technologies Corporation |
Alkyl chain modified imidazoquinoline derivatives as tlr7/8 agonists and uses thereof
|
|
WO2019089753A2
(en)
|
2017-10-31 |
2019-05-09 |
Compass Therapeutics Llc |
Cd137 antibodies and pd-1 antagonists and uses thereof
|
|
EP3710059A1
(en)
|
2017-11-14 |
2020-09-23 |
Dynavax Technologies Corporation |
Cleavable conjugates of tlr7/8 agonist compounds, methods for preparation, and uses thereof
|
|
US11851497B2
(en)
|
2017-11-20 |
2023-12-26 |
Compass Therapeutics Llc |
CD137 antibodies and tumor antigen-targeting antibodies and uses thereof
|
|
EP3728255B1
(en)
|
2017-12-20 |
2022-01-26 |
3M Innovative Properties Company |
Amide substituted imidazo[4,5-c]quinoline compounds with a branched chain linking group for use as an immune response modifier
|
|
CN110305210B
(zh)
|
2018-03-27 |
2023-02-28 |
信达生物制药(苏州)有限公司 |
新型抗体分子、其制备方法及其用途
|
|
WO2019184909A1
(zh)
|
2018-03-27 |
2019-10-03 |
信达生物制药(苏州)有限公司 |
新型抗体分子、其制备方法及其用途
|
|
WO2019232528A1
(en)
|
2018-06-01 |
2019-12-05 |
Xencor, Inc. |
Dosing of a bispecific antibody that bind cd123 and cd3
|
|
AU2020241686A1
(en)
|
2019-03-15 |
2021-11-04 |
Bolt Biotherapeutics, Inc. |
Immunoconjugates targeting HER2
|
|
US11179473B2
(en)
|
2020-02-21 |
2021-11-23 |
Silverback Therapeutics, Inc. |
Nectin-4 antibody conjugates and uses thereof
|
|
TW202146452A
(zh)
|
2020-02-28 |
2021-12-16 |
瑞士商諾華公司 |
結合cd123和cd3之雙特異性抗體的給藥
|
|
CN116209678A
(zh)
|
2020-07-01 |
2023-06-02 |
安尔士制药公司 |
抗asgr1抗体缀合物及其用途
|
|
US20230381304A1
(en)
*
|
2020-09-15 |
2023-11-30 |
Bharat Biotech International Limited |
Novel agonist vaccine formulation
|
|
CN112972688A
(zh)
*
|
2021-02-08 |
2021-06-18 |
吉林大学第一医院 |
PPARδ抑制剂联合免疫治疗药物在制备抗肿瘤药物中的应用
|
|
KR20240112760A
(ko)
*
|
2023-01-12 |
2024-07-19 |
주식회사 이뮤노맥스 |
항암능이 우수한 기억 t 세포 유래 면역세포치료제의 제조방법
|