JP2010510218A5 - - Google Patents
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- Publication number
- JP2010510218A5 JP2010510218A5 JP2009537218A JP2009537218A JP2010510218A5 JP 2010510218 A5 JP2010510218 A5 JP 2010510218A5 JP 2009537218 A JP2009537218 A JP 2009537218A JP 2009537218 A JP2009537218 A JP 2009537218A JP 2010510218 A5 JP2010510218 A5 JP 2010510218A5
- Authority
- JP
- Japan
- Prior art keywords
- tissue
- mammal
- composition
- administration
- site
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 210000001519 tissue Anatomy 0.000 claims 16
- 241000124008 Mammalia Species 0.000 claims 13
- 239000000427 antigen Substances 0.000 claims 6
- 102000036639 antigens Human genes 0.000 claims 6
- 108091007433 antigens Proteins 0.000 claims 6
- 229960005486 vaccine Drugs 0.000 claims 6
- 102000039446 nucleic acids Human genes 0.000 claims 4
- 108020004707 nucleic acids Proteins 0.000 claims 4
- 150000007523 nucleic acids Chemical class 0.000 claims 4
- 210000004207 dermis Anatomy 0.000 claims 2
- 238000004520 electroporation Methods 0.000 claims 2
- 210000003205 muscle Anatomy 0.000 claims 2
- 229920001184 polypeptide Polymers 0.000 claims 2
- 102000004196 processed proteins & peptides Human genes 0.000 claims 2
- 108090000765 processed proteins & peptides Proteins 0.000 claims 2
- 210000003491 skin Anatomy 0.000 claims 2
- 210000002460 smooth muscle Anatomy 0.000 claims 2
- 210000003699 striated muscle Anatomy 0.000 claims 2
- 230000002708 enhancing effect Effects 0.000 claims 1
- 230000028993 immune response Effects 0.000 claims 1
- 230000003053 immunization Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US85972406P | 2006-11-17 | 2006-11-17 | |
| US60/859,724 | 2006-11-17 | ||
| PCT/US2007/024051 WO2008063555A2 (en) | 2006-11-17 | 2007-11-16 | Methods of enhancing immune response using electroporation-assisted vaccination and boosting |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010510218A JP2010510218A (ja) | 2010-04-02 |
| JP2010510218A5 true JP2010510218A5 (enExample) | 2010-11-25 |
| JP5646851B2 JP5646851B2 (ja) | 2014-12-24 |
Family
ID=39430332
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009537218A Active JP5646851B2 (ja) | 2006-11-17 | 2007-11-16 | エレクトロポレーション支援ワクチン投与及び追加投与を用いた免疫応答の増強方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20100285040A1 (enExample) |
| EP (1) | EP2091558B1 (enExample) |
| JP (1) | JP5646851B2 (enExample) |
| KR (1) | KR20090080941A (enExample) |
| CN (1) | CN101522211A (enExample) |
| AU (1) | AU2007322075B2 (enExample) |
| CA (1) | CA2668649A1 (enExample) |
| WO (1) | WO2008063555A2 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010148440A1 (en) | 2009-06-24 | 2010-12-29 | International Scientific Pty Ltd | An apparatus and method of treatment utilizing a varying electromagnetic energisation profile |
| KR101723605B1 (ko) * | 2014-10-21 | 2017-04-07 | 진원생명과학 주식회사 | 대상포진 예방 및 치료용 dna 백신 조성물 및 이를 이용한 vzv 항원에 대한 t세포 활성화 방법 |
| US10233419B2 (en) | 2016-06-30 | 2019-03-19 | Zymergen Inc. | Apparatuses and methods for electroporation |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US118956A (en) * | 1871-09-12 | Improvement in apparatus for the manufacture of extracts from hemlock and other | ||
| US5273525A (en) | 1992-08-13 | 1993-12-28 | Btx Inc. | Injection and electroporation apparatus for drug and gene delivery |
| US6009345A (en) | 1992-08-17 | 1999-12-28 | Genetronics, Inc. | Method and apparatus for a combination of electroporation and iontophoresis for the delivery of drugs and genes |
| US5439440A (en) | 1993-04-01 | 1995-08-08 | Genetronics, Inc. | Electroporation system with voltage control feedback for clinical applications |
| US6261281B1 (en) | 1997-04-03 | 2001-07-17 | Electrofect As | Method for genetic immunization and introduction of molecules into skeletal muscle and immune cells |
| US6110161A (en) | 1997-04-03 | 2000-08-29 | Electrofect As | Method for introducing pharmaceutical drugs and nucleic acids into skeletal muscle |
| TW368420B (en) | 1997-11-04 | 1999-09-01 | Genetronics Inc | Apparatus and method for transdermal molecular delivery by applying sufficient amplitude of electric field to induce migration of molecules through pores in the stratum corneum |
| US6972013B1 (en) | 1998-07-13 | 2005-12-06 | Genetronics, Inc. | Enhanced delivery of naked DNA to skin by non-invasive in vivo electroporation |
| EP1148885A4 (en) * | 1999-02-08 | 2002-05-08 | Chiron Corp | ELECTRICALLY INDUCED INCREASE IN IMMUNITY AND EFFECTIVENESS OF IN VIVO DNA VACCINES |
| US7171264B1 (en) * | 1999-05-10 | 2007-01-30 | Genetronics, Inc. | Intradermal delivery of active agents by needle-free injection and electroporation |
| GB9922361D0 (en) * | 1999-09-21 | 1999-11-24 | Isis Innovation | Generating an immune response to an antigen |
| ES2386884T3 (es) * | 2000-11-01 | 2012-09-04 | The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Vectores de expresión capaces de inducir respuesta inmunomejorada y métodos para usarlos |
| CA2478614C (en) | 2001-03-13 | 2013-01-15 | University Of South Florida | Electromanipulation device and method |
| WO2003072016A2 (en) * | 2001-11-19 | 2003-09-04 | Becton, Dickinson And Company | Pharmaceutical compositions in particulate form |
| EP1474153A4 (en) * | 2001-12-14 | 2005-12-14 | Genetronics Inc | PARTICLE-ASSISTED IMMUNIZATION METHODS BASED ON THE USE OF A PULSE ELECTRIC FIELD |
| US20060035853A1 (en) * | 2004-01-07 | 2006-02-16 | Biomedical Research Models, Inc. | Methods for tailoring the immune response to an antigen or immunogen |
| EP1981581B1 (en) | 2006-02-11 | 2016-04-13 | Genetronics, Inc. | Device for single-needle in vivo electroporation |
-
2007
- 2007-11-16 AU AU2007322075A patent/AU2007322075B2/en active Active
- 2007-11-16 CN CNA200780037742XA patent/CN101522211A/zh active Pending
- 2007-11-16 US US11/985,871 patent/US20100285040A1/en not_active Abandoned
- 2007-11-16 JP JP2009537218A patent/JP5646851B2/ja active Active
- 2007-11-16 KR KR1020097007135A patent/KR20090080941A/ko not_active Ceased
- 2007-11-16 EP EP07840065.2A patent/EP2091558B1/en active Active
- 2007-11-16 CA CA002668649A patent/CA2668649A1/en not_active Abandoned
- 2007-11-16 WO PCT/US2007/024051 patent/WO2008063555A2/en not_active Ceased
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