|
US4711955A
(en)
|
1981-04-17 |
1987-12-08 |
Yale University |
Modified nucleotides and methods of preparing and using same
|
|
US4603112A
(en)
|
1981-12-24 |
1986-07-29 |
Health Research, Incorporated |
Modified vaccinia virus
|
|
US4596556A
(en)
|
1985-03-25 |
1986-06-24 |
Bioject, Inc. |
Hypodermic injection apparatus
|
|
FI861417A0
(fi)
|
1985-04-15 |
1986-04-01 |
Endotronics Inc |
Hepatitis b ytantigen framstaelld med rekombinant-dna-teknik, vaccin, diagnostiskt medel och cellinjer samt foerfaranden foer framstaellning daerav.
|
|
FR2583429B1
(fr)
|
1985-06-18 |
1989-11-03 |
Transgene Sa |
Vecteur d'expression de l'interferon u dans les cellules de mammifere, procede pour sa mise en oeuvre et produit obtenu et composition pharmaceutique contenant l'interferon u
|
|
FR2606029B2
(fr)
|
1986-04-08 |
1989-02-03 |
Transgene Sa |
Vecteur viral et adn recombinant codant pour une glycoproteine du virus agent causal du s.i.d.a., culture cellulaire infectee par ce vecteur, procede de preparation de la glycoproteine, glycoproteine obtenue, vaccin et anticorps obtenus
|
|
FR2643817B1
(fr)
|
1989-03-06 |
1993-12-17 |
Transgene Sa |
Composition pharmaceutique, utile a titre preventif ou curatif contre les tumeurs induites par les papillomavirus
|
|
EP0304578B1
(en)
|
1987-06-22 |
2001-10-24 |
Medeva Holdings Bv |
Peptide comprising hepatitis B surface antigen
|
|
US4873316A
(en)
|
1987-06-23 |
1989-10-10 |
Biogen, Inc. |
Isolation of exogenous recombinant proteins from the milk of transgenic mammals
|
|
FR2632863B2
(fr)
|
1987-10-29 |
1990-08-31 |
Transgene Sa |
Virus du fowlpox recombinant et vaccins derives de ces virus
|
|
GB8819209D0
(en)
|
1988-08-12 |
1988-09-14 |
Research Corp Ltd |
Polypeptide & dna encoding same
|
|
EP0414374B1
(en)
|
1989-07-25 |
1997-10-08 |
Smithkline Biologicals S.A. |
Novel antigens and methods for their preparation
|
|
FR2650838A1
(fr)
|
1989-08-09 |
1991-02-15 |
Transgene Sa |
Vecteurs d'expression du facteur ix dans une cellule eucaryote superieure, procede de preparation de facteur ix par des animaux transgeniques et facteur ix obtenu
|
|
US5108910A
(en)
|
1989-08-22 |
1992-04-28 |
Immunex Corporation |
DNA sequences encoding fusion proteins comprising GM-CSF and IL-3
|
|
US5670488A
(en)
|
1992-12-03 |
1997-09-23 |
Genzyme Corporation |
Adenovirus vector for gene therapy
|
|
FR2668064B1
(fr)
|
1990-10-23 |
1994-12-16 |
Transgene Sa |
Composition pharmaceutique pour le traitement ou la prevention d'une tumeur maligne.
|
|
GB9105383D0
(en)
|
1991-03-14 |
1991-05-01 |
Immunology Ltd |
An immunotherapeutic for cervical cancer
|
|
DE69233639T2
(de)
|
1991-07-19 |
2007-05-31 |
Csl Ltd., Parkville |
Polynukleotidabschnitt des HPV16-Genoms
|
|
CA2123612C
(en)
|
1991-11-16 |
2002-06-25 |
Michel De Wilde |
Hybrid protein between cs from plasmodium and h bsag
|
|
PT647140E
(pt)
|
1992-06-25 |
2007-12-27 |
Univ Georgetown |
Vacinas de papilomavírus
|
|
US5786148A
(en)
|
1996-11-05 |
1998-07-28 |
Incyte Pharmaceuticals, Inc. |
Polynucleotides encoding a novel prostate-specific kallikrein
|
|
GB9223084D0
(en)
|
1992-11-04 |
1992-12-16 |
Imp Cancer Res Tech |
Compounds to target cells
|
|
JPH08503855A
(ja)
|
1992-12-03 |
1996-04-30 |
ジェンザイム・コーポレイション |
嚢胞性線維症に対する遺伝子治療
|
|
US5747323A
(en)
|
1992-12-31 |
1998-05-05 |
Institut National De La Sante Et De La Recherche Medicale (Inserm) |
Retroviral vectors comprising a VL30-derived psi region
|
|
US5801029A
(en)
|
1993-02-16 |
1998-09-01 |
Onyx Pharmaceuticals, Inc. |
Cytopathic viruses for therapy and prophylaxis of neoplasia
|
|
ATE296111T1
(de)
|
1993-03-09 |
2005-06-15 |
Univ Rochester |
Herstellung von menschlichem papillomavirus hüllprotein und virus-ähnlichen teilchen
|
|
FR2705686B1
(fr)
|
1993-05-28 |
1995-08-18 |
Transgene Sa |
Nouveaux adénovirus défectifs et lignées de complémentation correspondantes.
|
|
US6133028A
(en)
|
1993-05-28 |
2000-10-17 |
Transgene S.A. |
Defective adenoviruses and corresponding complementation lines
|
|
FR2707091B1
(fr)
|
1993-06-30 |
1997-04-04 |
Cohen Haguenauer Odile |
Vecteur rétroviral pour le transfert et l'expression de gènes dans des cellules eucaryotes.
|
|
FR2711523B1
(fr)
|
1993-10-26 |
1996-02-16 |
Transgene Sa |
Procédé de préparation d'un aérosol viral.
|
|
US5698443A
(en)
|
1995-06-27 |
1997-12-16 |
Calydon, Inc. |
Tissue specific viral vectors
|
|
US5635599A
(en)
|
1994-04-08 |
1997-06-03 |
The United States Of America As Represented By The Department Of Health And Human Services |
Fusion proteins comprising circularly permuted ligands
|
|
US5525711A
(en)
|
1994-05-18 |
1996-06-11 |
The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services |
Pteridine nucleotide analogs as fluorescent DNA probes
|
|
CA2193488A1
(en)
|
1994-05-20 |
1995-11-30 |
Michele P. Calos |
An autonomous replication system for mammalian cells
|
|
US5998205A
(en)
|
1994-11-28 |
1999-12-07 |
Genetic Therapy, Inc. |
Vectors for tissue-specific replication
|
|
US6638762B1
(en)
|
1994-11-28 |
2003-10-28 |
Genetic Therapy, Inc. |
Tissue-vectors specific replication and gene expression
|
|
FR2727689A1
(fr)
|
1994-12-01 |
1996-06-07 |
Transgene Sa |
Nouveau procede de preparation d'un vecteur viral
|
|
FR2730735B1
(fr)
|
1995-02-20 |
1997-05-09 |
Pasteur Institut |
Sequences amplificatrices, vecteurs portant ces sequences et leurs utilisations dans des compositions pour l'expression de sequences nucleotidiques dans des cellules transfectees, applications therapeutiques et vaccinales
|
|
US5837520A
(en)
|
1995-03-07 |
1998-11-17 |
Canji, Inc. |
Method of purification of viral vectors
|
|
US5759776A
(en)
|
1995-06-05 |
1998-06-02 |
California Pacific Medical Center |
Targets for breast cancer diagnosis and treatment
|
|
AU705035B2
(en)
|
1995-06-07 |
1999-05-13 |
Baylor College Of Medicine |
Nucleic acid transporters for delivery of nucleic acids into a cell
|
|
UA68327C2
(en)
|
1995-07-04 |
2004-08-16 |
Gsf Forschungszentrum Fur Unwe |
A recombinant mva virus, an isolated eukaryotic cell, infected with recombinant mva virus, a method for production in vitro of polypeptides with use of said cell, a method for production in vitro of virus parts (variants), vaccine containing the recombinant mva virus, a method for immunization of animals
|
|
FR2737222B1
(fr)
|
1995-07-24 |
1997-10-17 |
Transgene Sa |
Nouveaux vecteurs viraux et lignee pour la therapie genique
|
|
US6090618A
(en)
|
1996-10-07 |
2000-07-18 |
Arch Development Corporation |
DNA constructs and viral vectors comprising a smooth muscle promoter
|
|
US6225446B1
(en)
*
|
1995-12-06 |
2001-05-01 |
Schering Corporation |
Mutational variants of mammalian proteins
|
|
FR2746815A1
(fr)
|
1996-03-26 |
1997-10-03 |
Pasteur Institut |
Sequences en amont du gene sm 22, vecteurs les contenant et leurs utilisations therapeutiques, notamment dans le traitement des maladies vasculaires
|
|
US5776683A
(en)
|
1996-07-11 |
1998-07-07 |
California Pacific Medical Center |
Methods for identifying genes amplified in cancer cells
|
|
CZ438398A3
(cs)
|
1996-07-01 |
1999-03-17 |
Rhone-Poulenc Rorer S. A. |
Způsob přípravy rekombinantních adenovirů
|
|
JP2001500015A
(ja)
|
1996-09-06 |
2001-01-09 |
トラステイーズ・オブ・ザ・ユニバーシテイ・オブ・ペンシルベニア |
Ｔ７ポリメラーゼを利用する組換えアデノ随伴ウイルスの誘導可能な製造方法
|
|
US5955306A
(en)
|
1996-09-17 |
1999-09-21 |
Millenium Pharmaceuticals, Inc. |
Genes encoding proteins that interact with the tub protein
|
|
US5994132A
(en)
|
1996-10-23 |
1999-11-30 |
University Of Michigan |
Adenovirus vectors
|
|
WO1998022588A2
(en)
|
1996-11-20 |
1998-05-28 |
Introgen Therapeutics, Inc. |
An improved method for the production and purification of adenoviral vectors
|
|
ATE353956T1
(de)
|
1996-12-13 |
2007-03-15 |
Schering Corp |
Methoden zur virus-reinigung
|
|
US5993412A
(en)
|
1997-05-19 |
1999-11-30 |
Bioject, Inc. |
Injection apparatus
|
|
FR2763958A1
(fr)
|
1997-05-29 |
1998-12-04 |
Transgene Sa |
Produit de combinaison associant un acide nucleique a une substance desorganisant la matrice extracellulaire pour la therapie genique
|
|
FR2763959A1
(fr)
|
1997-06-02 |
1998-12-04 |
Transgene Sa |
Nouveaux vecteurs adenoviraux recombinants comprenant une sequence d'epissage
|
|
WO1998056415A1
(en)
|
1997-06-11 |
1998-12-17 |
Aquila Biopharmaceuticals, Inc. |
Purified saponins as oral adjuvants
|
|
CA2242035C
(en)
|
1997-07-01 |
2004-11-23 |
Transgene S.A. |
Compositions useful for transferring therapeutically active substances into a target cell, and their use in gene therapy
|
|
FR2766091A1
(fr)
|
1997-07-18 |
1999-01-22 |
Transgene Sa |
Composition antitumorale a base de polypeptide immunogene de localisation cellulaire modifiee
|
|
AU1606999A
(en)
|
1997-11-26 |
1999-06-15 |
Albert Einstein College Of Medicine Of Yeshiva University |
Mouse telomerase reverse transcriptase
|
|
CN1285753A
(zh)
|
1997-12-02 |
2001-02-28 |
鲍德杰克特疫苗公司 |
透皮给药微粒疫苗组合物
|
|
ATE513042T1
(de)
|
1998-02-05 |
2011-07-15 |
Glaxosmithkline Biolog Sa |
Tumorassoziierte antigenderivate der mage-familie,nukleinsäuresequenzen, die dafür kodieren, zur herstellung von fusionsproteinen und zusammensetzungen zur impfung
|
|
AU748850B2
(en)
*
|
1998-04-02 |
2002-06-13 |
Regents Of The University Of California, The |
Methods for enhancing antigen-presenting cells and anti-tumor responses in a human patient
|
|
US6838081B1
(en)
|
1998-04-02 |
2005-01-04 |
The Regents Of The University Of California |
Methods for enhancing antigen-presenting cells and anti-tumor responses in a human patient
|
|
WO1999053061A2
(en)
|
1998-04-15 |
1999-10-21 |
Ludwig Institute For Cancer Research |
Tumor associated nucleic acids and uses therefor
|
|
EP0996739A2
(en)
|
1998-05-06 |
2000-05-03 |
Transgene S.A. |
Improvments in gene therapy using compositions comprising a polynucleotide and a nuclease inhibitor or interleukin-10
|
|
CN1107604C
(zh)
*
|
1998-05-15 |
2003-05-07 |
李振东 |
防夜间会车眩目的后灯侧灯车体灯
|
|
JP3864610B2
(ja)
|
1998-05-21 |
2007-01-10 |
旭硝子株式会社 |
水分散型撥水撥油剤組成物およびその製造方法
|
|
ES2180258T3
(es)
|
1998-07-07 |
2003-02-01 |
Transgene Sa |
Utilizacion de pautas de lectura abierta adenovirales de e4 para mejorar la expresion de genes.
|
|
JP2002520054A
(ja)
|
1998-07-14 |
2002-07-09 |
コリクサ コーポレイション |
前立腺癌の治療及び診断のための組成物及び方法
|
|
FR2782732A1
(fr)
|
1998-08-28 |
2000-03-03 |
Transgene Sa |
Systeme d'expression inductible
|
|
US6900049B2
(en)
|
1998-09-10 |
2005-05-31 |
Cell Genesys, Inc. |
Adenovirus vectors containing cell status-specific response elements and methods of use thereof
|
|
EP0998945A1
(en)
|
1998-09-30 |
2000-05-10 |
Transgene S.A. |
Use of magnesium (Mg2+) for the enhancement of gene delivery in gene therapy
|
|
US20020037274A1
(en)
|
1998-10-26 |
2002-03-28 |
Angelica Williams |
Single agent method for killing tumor and tumor associated endothelial cells using adenoviral mutants
|
|
US7217421B1
(en)
|
1998-11-03 |
2007-05-15 |
Cell Genesys, Inc. |
Cancer-associated antigens and methods of their identification and use
|
|
FR2787465A1
(fr)
|
1998-12-21 |
2000-06-23 |
Transgene Sa |
Procede d'inactivation des virus enveloppes dans une preparation virale de virus non enveloppes
|
|
CN1258738A
(zh)
*
|
1998-12-31 |
2000-07-05 |
上海华晨生物技术研究所 |
表达人粒细胞巨噬细胞集落刺激因子的重组腺病毒及其制法和用途
|
|
HUP0104794A3
(en)
|
1998-12-31 |
2006-03-28 |
Centelion |
Method for separating viral particles
|
|
CA2362367C
(en)
|
1999-02-04 |
2004-08-03 |
Geron Corporation |
Telomerase reverse transcriptase transcriptional regulatory sequences
|
|
WO2000050573A1
(fr)
|
1999-02-22 |
2000-08-31 |
Transgene S.A. |
Procede d'obtention d'une preparation virale purifiee
|
|
US6492169B1
(en)
|
1999-05-18 |
2002-12-10 |
Crucell Holland, B.V. |
Complementing cell lines
|
|
BR0013231A
(pt)
|
1999-08-09 |
2002-07-23 |
Lexigen Pharm Corp |
Complexos citocina-anticorpo múltiplos
|
|
AU776061B2
(en)
|
1999-11-15 |
2004-08-26 |
Onyx Pharmaceuticals |
An oncolytic adenovirus
|
|
AU782912B2
(en)
|
1999-12-28 |
2005-09-08 |
Association Francaise Contre Les Myopathies |
Use of lithium (Li+) for the preparation of a composition for transfection of a polynucleotide into a cell and compositions useful in gene therapy
|
|
CA2341356C
(en)
|
2000-04-14 |
2011-10-11 |
Transgene S.A. |
Poxvirus with targeted infection specificity
|
|
WO2002053760A2
(en)
|
2000-12-18 |
2002-07-11 |
Geron Corporation |
Chimeric cytolytic viruses for cancer treatment
|
|
WO2002096939A2
(en)
|
2001-05-30 |
2002-12-05 |
Transgene S.A. |
Adenovirus protein ix, its domains involved in capsid assembly, transcriptional activity and nuclear reorganization
|
|
EP1440090A2
(en)
*
|
2001-10-23 |
2004-07-28 |
Centre for Translational Research in Cancer |
A synthetic chimeric fusion protein with immuno-therapeutic uses
|
|
EP1310561A1
(en)
|
2001-11-09 |
2003-05-14 |
Transgene S.A. |
Chimeric promoters for controlling expression in skeletal muscle cells
|
|
GB0201679D0
(en)
|
2002-01-25 |
2002-03-13 |
Asterion Ltd |
Polypeptide variants
|
|
US20050053777A1
(en)
|
2003-09-06 |
2005-03-10 |
Hilliard Donald Bennett |
Pellicle
|
|
FR2862866B1
(fr)
|
2003-11-28 |
2006-12-15 |
Gilles Voydeville |
Prothese discale intervertebrale postero-laterale
|
|
PT1699822E
(pt)
|
2003-12-30 |
2008-07-30 |
Merck Patent Gmbh |
Proteínas de fusão de il-7
|
|
PL1868642T3
(pl)
*
|
2005-03-18 |
2013-10-31 |
Cytos Biotechnology Ag |
Białka fuzyjne alergenów kocich i ich zastosowania
|
|
CA2693326A1
(en)
|
2006-08-02 |
2008-02-07 |
Mcgill University |
Gm-csf and il-15 fusokines and methods for modulation of the immune response
|
|
WO2008053573A1
(fr)
|
2006-10-30 |
2008-05-08 |
National University Corporation Hokkaido University |
Remède pour néoplasme malin
|
|
CA2704232C
(en)
*
|
2007-11-08 |
2017-05-02 |
Dana-Farber Cancer Institute, Inc. |
Stimulation of anti-tumor immunity using dendritic cell/tumor cell fusions and anti-cd3/cd28
|
|
WO2010058713A1
(ja)
|
2008-11-21 |
2010-05-27 |
Dic株式会社 |
ポリアリ－レンスルフィド樹脂の製造方法
|
|
JP5797190B2
(ja)
*
|
2009-05-15 |
2015-10-21 |
アイ アール エックス セーラピューティクス， インコーポレイテッド |
ワクチン免疫療法
|
|
JP2013537172A
(ja)
*
|
2010-09-09 |
2013-09-30 |
トリフォイリウム エーピーエス |
血管新生阻害剤の気道投与
|
|
EP3587455A1
(en)
|
2012-10-23 |
2020-01-01 |
Emory University |
Gm-csf and il-4 conjugates, compositions, and methods related thereto
|