|
US3149109A
(en)
|
1962-02-20 |
1964-09-15 |
Searle & Co |
Certain 4-trifluoromethyl-2-(oxy/thio) pyrimidines
|
|
GB1121922A
(en)
|
1966-06-17 |
1968-07-31 |
Ici Ltd |
Pyrimidine derivatives
|
|
US5474995A
(en)
|
1993-06-24 |
1995-12-12 |
Merck Frosst Canada, Inc. |
Phenyl heterocycles as cox-2 inhibitors
|
|
ES2141916T3
(es)
|
1993-11-30 |
2000-04-01 |
Searle & Co |
Pirazolil-bencenosulfonamidas sustituidas para el tratamiento de la inflamacion.
|
|
US5418254A
(en)
*
|
1994-05-04 |
1995-05-23 |
G. D. Searle & Co. |
Substituted cyclopentadienyl compounds for the treatment of inflammation
|
|
FI970967A7
(fi)
|
1994-09-09 |
1997-03-07 |
Nippon Shinyaku Co Ltd |
Heterosyklinen johdannainen ja lääkeaine
|
|
EP0723960B1
(en)
|
1995-01-26 |
2003-04-02 |
Basf Aktiengesellschaft |
Herbicidal 2,6-disubstituted pyridines and 2,4-disubstituted pyrimidines
|
|
US5849758A
(en)
|
1995-05-30 |
1998-12-15 |
American Cyanamid Company |
Herbicidal 2, 6-disubstituted pyridines and 2, 4-disubstituted pyrimidines
|
|
US5596008A
(en)
|
1995-02-10 |
1997-01-21 |
G. D. Searle & Co. |
3,4-Diaryl substituted pyridines for the treatment of inflammation
|
|
US5700816A
(en)
|
1995-06-12 |
1997-12-23 |
Isakson; Peter C. |
Treatment of inflammation and inflammation-related disorders with a combination of a cyclooxygenase-2 inhibitor and a leukotriene A4 hydrolase inhibitor
|
|
WO1996041645A1
(en)
|
1995-06-12 |
1996-12-27 |
G.D. Searle & Co. |
Combination of a cyclooxygenase-2 inhibitor and a leukotriene b4 receptor antagonist for the treatment of inflammations
|
|
WO1997004781A1
(en)
|
1995-08-02 |
1997-02-13 |
Smithkline Beecham Corporation |
Endothelin receptor antagonists
|
|
US6020343A
(en)
|
1995-10-13 |
2000-02-01 |
Merck Frosst Canada, Inc. |
(Methylsulfonyl)phenyl-2-(5H)-furanones as COX-2 inhibitors
|
|
JPH09241161A
(ja)
|
1996-03-08 |
1997-09-16 |
Nippon Shinyaku Co Ltd |
医 薬
|
|
DE19614858A1
(de)
|
1996-04-16 |
1997-10-23 |
Basf Ag |
Herbizide heterocyclisch substituierte Benzoylisothiazole
|
|
IL127441A
(en)
|
1996-07-18 |
2003-02-12 |
Merck Frosst Canada Inc |
Substituted pyridines, pharmaceutical compositions comprising them and their use in the preparation of anti-inflammatory medicaments or as selective cyclooxygenase-2 inhibitors
|
|
EP0820996A1
(en)
|
1996-07-24 |
1998-01-28 |
American Cyanamid Company |
Herbicidal cyanopyridines
|
|
CZ298022B6
(cs)
|
1996-10-15 |
2007-05-30 |
G. D. Searle & Co. |
Použití inhibitoru cyklooxygenázy-2 pro výrobu léciva pro lécení a prevenci neoplazie
|
|
AR038955A1
(es)
|
1996-12-05 |
2005-02-02 |
Amgen Inc |
Compuestos de pirimidinona y piridona sustituidos y metodos para su uso
|
|
DE19651099A1
(de)
|
1996-12-09 |
1998-06-10 |
Consortium Elektrochem Ind |
Mehrkomponentensystem zum Verändern, Abbau oder Bleichen von Lignin, ligninhaltigen Materialien oder ähnlichen Stoffen sowie Verfahren zu seiner Anwendung
|
|
US5972842A
(en)
|
1996-12-12 |
1999-10-26 |
American Cyanamid Company |
Herbicidal cyanopyridines
|
|
DE19708928A1
(de)
|
1997-03-05 |
1998-09-10 |
Bayer Ag |
Substituierte aromatische Aminoverbindungen
|
|
WO1999001439A1
(en)
|
1997-07-03 |
1999-01-14 |
Du Pont Pharmaceuticals Company |
Aryl-and arylamino-substituted heterocycles as corticotropin releasing hormone antagonists
|
|
ES2256817T3
(es)
|
1997-09-05 |
2006-07-16 |
Glaxo Group Limited |
Composiciones farmaceuticas que comprenden derivados de 2,3-diaril-pirazolo(1,5-b)piridazina.
|
|
US5972986A
(en)
|
1997-10-14 |
1999-10-26 |
G.D. Searle & Co. |
Method of using cyclooxygenase-2 inhibitors in the treatment and prevention of neoplasia
|
|
EP1030843A4
(en)
|
1997-10-27 |
2002-11-06 |
Isk Americas Inc |
SUBSTITUTED BENZENE COMPOUNDS, METHOD FOR THE PRODUCTION THEREOF AND HERBICIDES AND LEAVING COMPOSITIONS THAT CONTAIN THEM
|
|
US6121202A
(en)
|
1997-11-07 |
2000-09-19 |
American Cyanamid Company |
Thienyloxypyridines and-pyrimidines useful as herbicidal agents
|
|
JP2000026421A
(ja)
|
1998-01-29 |
2000-01-25 |
Kumiai Chem Ind Co Ltd |
ジアリ―ルスルフィド誘導体及び有害生物防除剤
|
|
US6306866B1
(en)
|
1998-03-06 |
2001-10-23 |
American Cyanamid Company |
Use of aryl-substituted pyrimidines as insecticidal and acaricidal agents
|
|
DE19909541A1
(de)
|
1998-03-06 |
1999-10-14 |
American Cyanamid Co |
Herbizide 2-Aryloxy- bzw. 2-Arylthio-6-arylpyrimidine
|
|
AU3536699A
(en)
|
1998-04-27 |
1999-11-16 |
Ihara Chemical Industry Co. Ltd. |
3-arylphenyl sulfide derivatives and insecticides and miticides
|
|
DE19831246A1
(de)
|
1998-07-11 |
2000-01-13 |
Clariant Gmbh |
Verfahren zur Herstellung von Arylpyridinen
|
|
HUP0104204A3
(en)
|
1998-11-03 |
2002-06-28 |
Glaxo Group Ltd |
Pyrazolopyridine derivatives as cox-2 inhibitors, process for their preparation and pharmaceutical compositions thereof
|
|
CA2361428A1
(en)
|
1999-02-11 |
2000-08-17 |
Cor Therapeutics, Inc. |
Inhibitors of factor xa
|
|
US6313072B1
(en)
|
1999-02-18 |
2001-11-06 |
American Cyanamid Company |
Herbicidal 2-aryloxy-or 2-arylthio-6-arylpyrimidines
|
|
US6498166B1
(en)
|
1999-02-27 |
2002-12-24 |
Smithkline Beecham Corporation |
Pyrazolopyridines
|
|
JP4570057B2
(ja)
|
1999-09-09 |
2010-10-27 |
三菱レイヨン株式会社 |
アリールピリジン誘導体の製造法
|
|
GB9927844D0
(en)
|
1999-11-26 |
2000-01-26 |
Glaxo Group Ltd |
Chemical compounds
|
|
PT1104760E
(pt)
*
|
1999-12-03 |
2003-06-30 |
Pfizer Prod Inc |
Compostos de sulfamoil-heteroarilpirazole como agentes analgesicos e anti-inflamatorios
|
|
ATE283048T1
(de)
|
1999-12-08 |
2004-12-15 |
Pharmacia Corp |
Cyclooxygenase-2 hemmer enthaltende zusammensetzungen mit schnellem wirkungseintritt
|
|
GB9930358D0
(en)
|
1999-12-22 |
2000-02-09 |
Glaxo Group Ltd |
Process for the preparation of chemical compounds
|
|
CA2393724A1
(en)
|
1999-12-23 |
2001-06-28 |
Nitromed, Inc. |
Nitrosated and nitrosylated cyclooxygenase-2 inhibitors, compositions and methods of use
|
|
GB0002312D0
(en)
|
2000-02-01 |
2000-03-22 |
Glaxo Group Ltd |
Medicaments
|
|
GB0002336D0
(en)
|
2000-02-01 |
2000-03-22 |
Glaxo Group Ltd |
Medicaments
|
|
GB0003224D0
(en)
|
2000-02-11 |
2000-04-05 |
Glaxo Group Ltd |
Chemical compounds
|
|
JP4064671B2
(ja)
|
2000-02-25 |
2008-03-19 |
エフ.ホフマン−ラ ロシュ アーゲー |
アデノシン受容体モジュレーター
|
|
AU2001232175B2
(en)
*
|
2000-03-03 |
2005-07-07 |
Pfizer Products Inc. |
Pyrazole ether derivatives as anti-inflammatory/analgesic agents
|
|
JP2001252044A
(ja)
|
2000-03-15 |
2001-09-18 |
Healthy Shokuhin Kk |
五大栄養素調合食品薬膳
|
|
JP2003531906A
(ja)
|
2000-04-28 |
2003-10-28 |
グラクソ グループ リミテッド |
ピラゾロピリジン誘導体の製造方法
|
|
EP1296982B1
(en)
|
2000-06-23 |
2007-09-19 |
Bristol-Myers Squibb Pharma Company |
1-(heteroaryl-phenyl)-condensed pyrazol derivatives as factor xa inhibitors
|
|
AU2001268711A1
(en)
|
2000-06-23 |
2002-01-08 |
Bristol-Myers Squibb Pharma Company |
Heteroaryl-phenyl substituted factor xa inhibitors
|
|
GB0021494D0
(en)
*
|
2000-09-01 |
2000-10-18 |
Glaxo Group Ltd |
Chemical comkpounds
|
|
DE10059418A1
(de)
|
2000-11-30 |
2002-06-20 |
Aventis Pharma Gmbh |
Ortho, meta-substituierte Bisarylverbindungen, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament sowie sie enthaltende pharmazeutische Zubereitungen
|
|
WO2002055484A1
(en)
|
2001-01-12 |
2002-07-18 |
Takeda Chemical Industries, Ltd. |
Biaryl compound, process for producing the same, and agent
|
|
WO2002059122A1
(en)
|
2001-01-24 |
2002-08-01 |
Auckland Uniservices Limited |
ANTI-CANCER 2,3-DIHYDRO-1H-PYRROLO[3,2-f]QUINOLINE COMPLEXES OF COBALT AND CHROMIUM
|
|
US6960595B2
(en)
|
2001-03-23 |
2005-11-01 |
Bristol-Myers Squibb Pharma Company |
5-6 to 5-7 Heterobicycles as factor Xa inhibitors
|
|
US6756498B2
(en)
|
2001-04-27 |
2004-06-29 |
Smithkline Beecham Corporation |
Process for the preparation of chemical compounds
|
|
GB0112803D0
(en)
|
2001-05-25 |
2001-07-18 |
Glaxo Group Ltd |
Pyrimidine derivatives
|
|
GB0112802D0
(en)
|
2001-05-25 |
2001-07-18 |
Glaxo Group Ltd |
Pyrimidine derivatives
|
|
GB0112810D0
(en)
|
2001-05-25 |
2001-07-18 |
Glaxo Group Ltd |
Pyrimidine derivatives
|
|
RU2003136151A
(ru)
|
2001-06-12 |
2005-05-20 |
Ньюроджин Корпорейшн (US) |
2, 5-диарилпиразины, 2, 5-диарилпиридины и 2, 5-диарилпиримидины в качестве модуляторов рецептора кортикотропин-рилизинг-фактора 1 (крф1)
|
|
SE0102439D0
(sv)
|
2001-07-05 |
2001-07-05 |
Astrazeneca Ab |
New compounds
|
|
GB0119477D0
(en)
|
2001-08-09 |
2001-10-03 |
Glaxo Group Ltd |
Pyrimidine derivatives
|
|
GB0119472D0
(en)
|
2001-08-09 |
2001-10-03 |
Astrazeneca Ab |
Compounds
|
|
US6667311B2
(en)
|
2001-09-11 |
2003-12-23 |
Albany Molecular Research, Inc. |
Nitrogen substituted biaryl purine derivatives as potent antiproliferative agents
|
|
GB0206200D0
(en)
|
2002-03-15 |
2002-05-01 |
Glaxo Group Ltd |
Pharmaceutical compositions
|
|
US6861249B1
(en)
|
2002-04-09 |
2005-03-01 |
David Kent |
Microbial spray for animal waste
|
|
ATE325115T1
(de)
|
2002-08-19 |
2006-06-15 |
Glaxo Group Ltd |
Pyrimidinderivate als selektive cox-2-inhibitoren
|
|
GB0221443D0
(en)
|
2002-09-16 |
2002-10-23 |
Glaxo Group Ltd |
Pyridine derivates
|
|
GB0227443D0
(en)
|
2002-11-25 |
2002-12-31 |
Glaxo Group Ltd |
Pyrimidine derivatives
|
|
GB0319037D0
(en)
|
2003-08-13 |
2003-09-17 |
Glaxo Group Ltd |
7-Azaindole Derivatives
|